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• Activity deltas table
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Motif ID: PAX6.p2

Z-value: 0.458

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_150480584	1.961		ECM1	extracellular matrix protein 1
chr7_+_80267972	1.733		CD36	CD36 molecule (thrombospondin receptor)
chr11_-_58343308	1.657	NM_004811	LPXN	leupaxin
chr6_-_131291480	1.081	NM_001199389	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr6_-_42162693	0.981	NM_002098	GUCA1B	guanylate cyclase activator 1B (retina)
chr1_-_6580068	0.913	NM_198681	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_-_73123431	0.894		STX1A	syntaxin 1A (brain)
chr5_+_147691988	0.796	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr12_+_56915587	0.786	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr1_+_150480486	0.760	NM_001202858 NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr4_-_68749698	0.714	NM_004262	TMPRSS11D	transmembrane protease, serine 11D
chr18_+_61420276	0.679	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr7_+_80267922	0.603		CD36	CD36 molecule (thrombospondin receptor)
chr4_-_174320616	0.561	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr1_-_153044083	0.520	NM_001017418	SPRR2B	small proline-rich protein 2B
chr6_-_131321868	0.461	NM_001252660	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chrX_-_65259839	0.433	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr16_+_72088507	0.337	NM_001126102 NM_005143	HP	haptoglobin
chrX_-_130423199	0.333		IGSF1	immunoglobulin superfamily, member 1
chr21_+_39644428	0.329	NM_170737	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_113236679	0.325		MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_209878135	0.315	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr6_-_46703429	0.292	NM_001168357	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_+_58499854	0.286	NM_181707	C17orf64	chromosome 17 open reading frame 64
chr7_+_80267782	0.280	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr1_-_12908141	0.272	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr7_+_155250705	0.265	NM_001427	EN2	engrailed homeobox 2
chr11_+_117947785	0.263		TMPRSS4	transmembrane protease, serine 4
chr20_-_1309809	0.261	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr5_-_142077508	0.248	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr17_-_9694613	0.246	NM_001105571 NM_001220493	DHRS7C	dehydrogenase/reductase (SDR family) member 7C
chr11_+_844445	0.245	NM_001025237	TSPAN4	tetraspanin 4
chr2_+_115822246	0.243	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr6_+_152126807	0.231	NM_001122741	ESR1	estrogen receptor 1
chr11_+_117947726	0.225	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr12_-_70093064	0.214	NM_032735	BEST3	bestrophin 3
chr2_+_62934030	0.206	NM_001142614	EHBP1	EH domain binding protein 1
chr4_+_113970784	0.200	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr5_+_57787260	0.199	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr2_-_171923482	0.198	NM_001136555	TLK1	tousled-like kinase 1
chr21_+_39628869	0.196	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chrX_-_138914384	0.186	NM_001010986 NM_173694	ATP11C	ATPase, class VI, type 11C
chr4_-_10686314	0.184	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr8_+_124194873	0.176		FAM83A	family with sequence similarity 83, member A
chr13_-_110802708	0.176		COL4A1	collagen, type IV, alpha 1
chr6_+_42896859	0.170	NM_006586	CNPY3	canopy 3 homolog (zebrafish)
chr10_+_35894337	0.166	NM_153368	GJD4	gap junction protein, delta 4, 40.1kDa
chrX_+_148769902	0.160	NM_001011544	MAGEA11	melanoma antigen family A, 11
chr5_-_114938060	0.156	NM_021649	TICAM2	toll-like receptor adaptor molecule 2
chr4_-_65275000	0.155	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chrX_+_2670092	0.146	NM_001141919 NM_001141920 NM_175569	XGPY2 XG	Xg pseudogene, Y-linked 2 Xg blood group
chr12_-_2986299	0.143	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr2_-_163008913	0.138	NM_002054	GCG	glucagon
chr7_+_80275634	0.137	NM_001127443 NM_001127444	CD36	CD36 molecule (thrombospondin receptor)
chr17_+_9745847	0.137		GLP2R	glucagon-like peptide 2 receptor
chr2_-_133539627	0.131		NCKAP5	NCK-associated protein 5
chr6_-_48078909	0.131		C6orf138	chromosome 6 open reading frame 138
chr17_-_34503914	0.130	NM_001001417	TBC1D3B TBC1D3C TBC1D3G	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G
chr3_-_128186090	0.126	NM_153330	DNAJB8	DnaJ (Hsp40) homolog, subfamily B, member 8
chr4_+_187148624	0.126	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr6_+_101846668	0.122		GRIK2	glutamate receptor, ionotropic, kainate 2
chr3_-_147123306	0.119	NM_001168379	ZIC4	Zic family member 4
chrX_-_124097601	0.117	NM_001163278 NM_001163279 NM_014253	ODZ1	odz, odd Oz/ten-m homolog 1 (Drosophila)
chrX_-_53461291	0.116	NM_001037811 NM_004493	HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10
chr12_+_18414473	0.114	NM_004570	PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide
chr3_-_119379269	0.111	NM_022135	POPDC2	popeye domain containing 2
chr7_-_108142934	0.105		PNPLA8	patatin-like phospholipase domain containing 8
chr8_-_62602285	0.103	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr17_-_36348585	0.102	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chr5_-_141338626	0.101	NM_016580	PCDH12	protocadherin 12
chr12_-_80329234	0.100	NM_001143885 NM_001244990	PPP1R12A	protein phosphatase 1, regulatory subunit 12A
chr3_+_133495925	0.097		TF	transferrin
chr3_+_136649316	0.096	NM_001190796	NCK1	NCK adaptor protein 1
chr17_-_34756980	0.096	NM_001123392	TBC1D3C TBC1D3G TBC1D3 TBC1D3H	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H
chr15_-_50405512	0.092		ATP8B4	ATPase, class I, type 8B, member 4
chr6_-_155777036	0.091	NM_015718	NOX3	NADPH oxidase 3
chrX_-_130423387	0.090	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chrX_+_49832214	0.089	NM_000084	CLCN5	chloride channel 5
chr11_+_14926542	0.088		CALCB	calcitonin-related polypeptide beta
chr3_-_195310770	0.087		APOD	apolipoprotein D
chr4_+_88896801	0.086	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr6_+_167704802	0.086	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr17_+_36283959	0.085	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chr5_+_40909558	0.082	NM_000587	C7	complement component 7
chr3_-_194188967	0.079	NM_024524	ATP13A3	ATPase type 13A3
chr7_+_110731061	0.078	NM_001099658 NM_001099660 NM_018334	LRRN3	leucine rich repeat neuronal 3
chr14_-_88737160	0.078	NM_138318	KCNK10	potassium channel, subfamily K, member 10
chr2_-_200325200	0.073		SATB2	SATB homeobox 2
chr19_+_7968820	0.071		MAP2K7	mitogen-activated protein kinase kinase 7
chr17_-_39023461	0.071	NM_000223	KRT12	keratin 12
chr6_+_30691151	0.070		TUBB	tubulin, beta class I
chr17_-_34591958	0.070	NM_001001418	TBC1D3C TBC1D3G	TBC1 domain family, member 3C TBC1 domain family, member 3G
chr6_-_64029847	0.068	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr11_-_117747331	0.065		FXYD6	FXYD domain containing ion transport regulator 6
chrY_-_27198250	0.059	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chr1_+_97260515	0.058
chr8_-_93111915	0.057	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_139349818	0.057	NM_021243	C6orf115	chromosome 6 open reading frame 115
chr13_+_53602829	0.057	NM_006418	OLFM4	olfactomedin 4
chr2_-_162931051	0.055	NM_001935	DPP4	dipeptidyl-peptidase 4
chr8_-_95487284	0.054	NM_001205262 NM_012415	RAD54B	RAD54 homolog B (S. cerevisiae)
chr11_+_76883823	0.053		MYO7A	myosin VIIA
chr7_+_45067232	0.053	NM_001029835	CCM2	cerebral cavernous malformation 2
chr1_-_211666258	0.053	NM_001164688 NM_183059	RD3	retinal degeneration 3
chr4_+_56261763	0.052
chr6_-_10412606	0.052	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_-_94224601	0.051		MCTP1	multiple C2 domains, transmembrane 1
chrX_+_103357106	0.050	NM_001143978	ZCCHC18	zinc finger, CCHC domain containing 18
chr4_-_26491888	0.049	NM_000730	CCKAR	cholecystokinin A receptor
chrY_+_25130409	0.047	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chrY_+_26764150	0.047	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chr3_+_111717585	0.046	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr17_-_39041436	0.045	NM_019010	KRT20	keratin 20
chr3_-_36781351	0.045	NM_033403	DCLK3	doublecortin-like kinase 3
chr3_+_119500930	0.043		NR1I2	nuclear receptor subfamily 1, group I, member 2
chr1_+_184356186	0.042		C1orf21	chromosome 1 open reading frame 21
chr5_+_85913755	0.041		COX7C	cytochrome c oxidase subunit VIIc
chr12_-_133215775	0.041		POLE	polymerase (DNA directed), epsilon
chr12_+_8666135	0.040	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr9_-_16870664	0.040		BNC2	basonuclin 2
chr5_+_175223519	0.039	NM_006650	CPLX2	complexin 2
chr18_-_47806361	0.039	NM_001204151	MBD1	methyl-CpG binding domain protein 1
chr19_-_54327428	0.038	NM_144687	NLRP12	NLR family, pyrin domain containing 12
chr4_+_71263598	0.037	NM_021225	PROL1	proline rich, lacrimal 1
chr10_+_83637442	0.036	NM_001165973	NRG3	neuregulin 3
chr6_-_75994631	0.036	NM_001143958 NM_018247	TMEM30A	transmembrane protein 30A
chr11_+_124095343	0.034	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chr1_+_203766650	0.034	NM_001174108	ZBED6	zinc finger, BED-type containing 6
chr10_+_102222797	0.032	NM_003393	WNT8B	wingless-type MMTV integration site family, member 8B
chr20_-_45927496	0.032		ZMYND8	zinc finger, MYND-type containing 8
chr9_-_95244750	0.031	NM_001193335 NM_017680	ASPN	asporin
chr19_+_55249973	0.031	NM_015868	KIR2DL3	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
chr1_+_186798031	0.030	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr9_-_14779530	0.030	NM_001177704	FREM1	FRAS1 related extracellular matrix 1
chr10_-_46030798	0.029	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr6_-_35480635	0.029	NM_003322	TULP1	tubby like protein 1
chr3_-_108248168	0.028	NM_014981	MYH15	myosin, heavy chain 15
chr3_-_14583587	0.025	NM_001080423	GRIP2	glutamate receptor interacting protein 2
chr10_+_124030820	0.025	NM_144587	BTBD16	BTB (POZ) domain containing 16
chr21_-_39870303	0.024	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr5_-_142815076	0.024	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_+_160147200	0.024	NM_001001734	ATP1A4	ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr5_-_58882274	0.023	NM_006203	PDE4D	phosphodiesterase 4D, cAMP-specific
chr1_+_159409511	0.022	NM_012351	OR10J1	olfactory receptor, family 10, subfamily J, member 1
chr8_-_87755880	0.021	NM_019098	CNGB3	cyclic nucleotide gated channel beta 3
chr20_-_44144263	0.021	NM_006652	SPINT3	serine peptidase inhibitor, Kunitz type, 3
chr4_+_71226477	0.021	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr12_-_7848324	0.020	NM_020634	GDF3	growth differentiation factor 3
chr7_+_73275488	0.019	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr16_-_51184507	0.019	NM_001127892	SALL1	sal-like 1 (Drosophila)
chr12_+_10460416	0.018	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr7_-_26232148	0.014		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr4_+_15429628	0.014	NM_031911	C1QTNF7	C1q and tumor necrosis factor related protein 7
chr1_+_147374945	0.013	NM_005267	GJA8	gap junction protein, alpha 8, 50kDa
chr5_+_152870083	0.013	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chr14_+_102276125	0.013	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr2_-_99871569	0.013	NM_175735	LYG2	lysozyme G-like 2
chr9_-_95166827	0.012	NM_014057 NM_033014	OGN	osteoglycin
chr3_+_119501556	0.012	NM_022002	NR1I2	nuclear receptor subfamily 1, group I, member 2
chr15_+_29213839	0.012	NM_001130414 NM_005503	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2
chr10_-_94257470	0.012	NM_001165946	IDE	insulin-degrading enzyme
chr5_-_169724734	0.011		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr18_+_18822168	0.011	NM_001142966	GREB1L	growth regulation by estrogen in breast cancer-like
chr5_-_169724817	0.010	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_35851101	0.010		ZMYM4	zinc finger, MYM-type 4
chr1_-_154832187	0.009	NM_170782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr9_-_85946875	0.009	NM_001244961	FRMD3	FERM domain containing 3
chr11_+_19372270	0.009	NM_001111018	NAV2	neuron navigator 2
chr1_+_158901336	0.009	NM_152501 NM_198928 NM_198929 NM_198930	PYHIN1	pyrin and HIN domain family, member 1
chr16_+_70147528	0.008	NM_017990	PDPR	pyruvate dehydrogenase phosphatase regulatory subunit
chrX_-_131573638	0.007	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chr11_+_59824054	0.007	NM_001031666 NM_001031809 NM_006138	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr5_+_143191725	0.006	NM_021182	HMHB1	histocompatibility (minor) HB-1
chr1_-_182922504	0.005	NM_030933	SHCBP1L	SHC SH2-domain binding protein 1-like
chr3_+_49506079	0.005	NM_001177643	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr2_-_99279935	0.005	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr3_+_25470067	0.004		RARB	retinoic acid receptor, beta
chr8_+_7705401	0.004	NM_058203 NM_001081552	SPAG11B SPAG11A	sperm associated antigen 11B sperm associated antigen 11A
chr2_-_175499275	0.004	NM_003387	WIPF1	WAS/WASL interacting protein family, member 1
chr5_-_35048239	0.004	NM_031900	AGXT2	alanine--glyoxylate aminotransferase 2
chr12_-_57504088	0.003	NM_001178079	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr13_+_24844846	0.003		SPATA13	spermatogenesis associated 13
chr14_+_29241989	0.002		C14orf23	chromosome 14 open reading frame 23
chrX_-_15333726	0.001	NM_001201583 NM_080873	ASB11	ankyrin repeat and SOCS box containing 11
chr1_-_89458256	0.001		RBMXL1 CCBL2	RNA binding motif protein, X-linked-like 1 cysteine conjugate-beta lyase 2
chr6_-_136788012	0.001	NM_001198615	MAP7	microtubule-associated protein 7
chr12_-_71031174	0.001	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr5_+_140734767	0.000	NM_018917 NM_032053	PCDHGA4	protocadherin gamma subfamily A, 4
chr6_+_14117486	0.000	NM_001251901	CD83	CD83 molecule

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
11.79	7.63e-03	GO:0032313	regulation of Rab GTPase activity
11.79	7.63e-03	GO:0032483	regulation of Rab protein signal transduction

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.01	1.42e-03	GO:0005576	extracellular region

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
11.56	2.17e-03	GO:0005097	Rab GTPase activator activity