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• Activity deltas table
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Motif ID: PBX1.p2

Z-value: 0.883

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_-_39190103	4.848		DNAL4	dynein, axonemal, light chain 4
chr22_-_39190146	4.526	NM_005740	DNAL4	dynein, axonemal, light chain 4
chr1_+_85527992	3.779	NM_145172	WDR63	WD repeat domain 63
chr10_+_63422718	3.559	NM_173554	C10orf107	chromosome 10 open reading frame 107
chr9_+_140135738	3.193		TUBB4B	tubulin, beta 4B class IVb
chr12_-_113658826	3.006	NM_138451	IQCD	IQ motif containing D
chr3_+_129158949	2.987	NM_018262 NM_052985 NM_052989 NM_052990	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159075	2.946		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159150	2.945		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159138	2.908		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159089	2.899		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr9_+_140135698	2.833	NM_006088	TUBB4B	tubulin, beta 4B class IVb
chr4_-_186300151	2.796	NM_018409	LRP2BP	LRP2 binding protein
chr8_+_99076749	2.635	NM_001170806 NM_173549	C8orf47	chromosome 8 open reading frame 47
chr9_+_140135742	2.548		TUBB4B	tubulin, beta 4B class IVb
chr7_-_138363789	2.495	NM_001139456	SVOPL	SVOP-like
chr3_-_121553907	1.761	NM_001023570 NM_001023571	IQCB1	IQ motif containing B1
chr6_-_32557431	1.718	NM_001243965 NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr3_-_121553836	1.685		IQCB1	IQ motif containing B1
chr13_-_61989209	1.631		PCDH20	protocadherin 20
chr2_-_154335181	1.553	NM_019845	RPRM	reprimo, TP53 dependent G2 arrest mediator candidate
chr5_+_140018998	1.525	NM_018502	TMCO6	transmembrane and coiled-coil domains 6
chr11_+_73661363	1.477	NM_153614	DNAJB13	DnaJ (Hsp40) homolog, subfamily B, member 13
chr15_+_43809805	1.474	NM_002373	MAP1A	microtubule-associated protein 1A
chr6_+_135502477	1.430		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr12_+_21168629	1.408	NM_001009562	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_-_167040700	1.360	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_149858114	1.317	NM_003528	HIST2H2BE	histone cluster 2, H2be
chr2_+_219135114	1.312	NM_001077399 NM_015488	PNKD	paroxysmal nonkinesigenic dyskinesia
chr15_-_37391893	1.295		MEIS2	Meis homeobox 2
chr4_-_69886112	1.292	NM_001075 NM_001144767	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10
chr17_+_58755158	1.272	NM_001099432 NM_017679	BCAS3	breast carcinoma amplified sequence 3
chr13_-_61989654	1.267	NM_022843	PCDH20	protocadherin 20
chr3_-_112564789	1.253	NM_001008784 NM_001199215	CD200R1L	CD200 receptor 1-like
chr1_+_151630710	1.227		SNX27	sorting nexin family member 27
chr18_+_44526786	1.221	NM_031303	KATNAL2	katanin p60 subunit A-like 2
chr2_+_12856813	1.197	NM_021643	TRIB2	tribbles homolog 2 (Drosophila)
chr5_+_43602738	1.184	NM_012343	NNT	nicotinamide nucleotide transhydrogenase
chr13_+_97928414	1.184		MBNL2	muscleblind-like 2 (Drosophila)
chr16_+_30907927	1.176	NM_001142544 NM_001330	CTF1	cardiotrophin 1
chr13_+_36050885	1.156	NM_001204197	NBEA	neurobeachin
chr7_+_29603388	1.141	NM_175887	PRR15	proline rich 15
chr10_+_69869249	1.126	NM_032578	MYPN	myopalladin
chr14_+_76127550	1.070	NM_015072	TTLL5	tubulin tyrosine ligase-like family, member 5
chr18_-_53177999	1.058	NM_001243231	TCF4	transcription factor 4
chr14_+_24584321	1.031		DCAF11	DDB1 and CUL4 associated factor 11
chr13_+_43355685	1.030	NM_182508	C13orf30	chromosome 13 open reading frame 30
chr2_+_183943468	1.005		DUSP19	dual specificity phosphatase 19
chr5_+_43603216	1.000	NM_182977	NNT	nicotinamide nucleotide transhydrogenase
chr5_+_43603312	0.990		NNT	nicotinamide nucleotide transhydrogenase
chr16_+_15596122	0.960	NM_001142469	C16orf45	chromosome 16 open reading frame 45
chr9_-_99382073	0.947	NM_003671 NM_033331	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr6_+_135502521	0.921		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr15_-_93616308	0.920		RGMA	RGM domain family, member A
chr3_+_63638343	0.907	NM_001080537	SNTN	sentan, cilia apical structure protein
chr1_+_60280462	0.905	NM_015888	HOOK1	hook homolog 1 (Drosophila)
chr2_+_183943286	0.892	NM_001142314 NM_080876	DUSP19	dual specificity phosphatase 19
chr17_+_1619816	0.887	NM_001163673 NM_152348	WDR81	WD repeat domain 81
chr19_-_50528683	0.865	NM_001025778 NM_016440	VRK3	vaccinia related kinase 3
chr20_+_57022460	0.857		VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr1_-_217250230	0.855	NM_001243507 NM_001243509	ESRRG	estrogen-related receptor gamma
chr15_-_93616358	0.842	NM_001166286	RGMA	RGM domain family, member A
chr14_+_76127656	0.829		TTLL5	tubulin tyrosine ligase-like family, member 5
chr15_-_37393364	0.820	NM_001220482 NM_002399	MEIS2	Meis homeobox 2
chr19_-_41870001	0.820	NM_030578	B9D2	B9 protein domain 2
chr19_+_49375677	0.819		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr9_-_37465384	0.812	NM_014872	ZBTB5	zinc finger and BTB domain containing 5
chr4_-_84035888	0.807		PLAC8	placenta-specific 8
chr19_+_49375679	0.806		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr17_+_21030236	0.789	NM_015510	DHRS7B	dehydrogenase/reductase (SDR family) member 7B
chr5_+_43603287	0.787		NNT	nicotinamide nucleotide transhydrogenase
chr2_-_219134795	0.782		AAMP	angio-associated, migratory cell protein
chr2_-_219134865	0.769	NM_001087	AAMP	angio-associated, migratory cell protein
chr19_+_49375638	0.769	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr4_+_77356252	0.763	NM_020859	SHROOM3	shroom family member 3
chr16_+_78062985	0.762	NM_001244755	CLEC3A	C-type lectin domain family 3, member A
chr1_+_118148506	0.761	NM_017709	FAM46C	family with sequence similarity 46, member C
chr18_-_59854179	0.751		PIGN	phosphatidylinositol glycan anchor biosynthesis, class N
chr19_-_50528627	0.748		VRK3	vaccinia related kinase 3
chr17_+_17876126	0.736	NM_001130090 NM_001130091 NM_001130092 NM_031294	LRRC48	leucine rich repeat containing 48
chr2_-_219134846	0.714		AAMP	angio-associated, migratory cell protein
chr18_-_59854288	0.713	NM_012327 NM_176787	PIGN	phosphatidylinositol glycan anchor biosynthesis, class N
chr16_+_67927170	0.712	NM_006742	PSKH1	protein serine kinase H1
chr2_+_183943511	0.711		DUSP19	dual specificity phosphatase 19
chr1_+_104159953	0.703	NM_000699	AMY2A	amylase, alpha 2A (pancreatic)
chr10_+_99498233	0.689	NM_001002261	ZFYVE27	zinc finger, FYVE domain containing 27
chr6_+_27114860	0.682	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chrX_-_10645726	0.675	NM_001098624	MID1	midline 1 (Opitz/BBB syndrome)
chr17_-_41977966	0.672		MPP2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr10_+_76586299	0.650	NM_012330	KAT6B	K(lysine) acetyltransferase 6B
chr7_-_77325539	0.630
chr14_-_93673360	0.629	NM_032490	C14orf142	chromosome 14 open reading frame 142
chr16_+_19078958	0.627		COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr6_-_167040659	0.619		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_+_18079176	0.619	NM_001160174	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr2_-_135782246	0.615	NM_001018046 NM_025052	YSK4	YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
chr12_+_41831484	0.614	NM_013377	PDZRN4	PDZ domain containing ring finger 4
chr16_-_3493489	0.608	NM_152457	ZNF597	zinc finger protein 597
chr15_-_77712436	0.608	NM_024776	PEAK1	NKF3 kinase family member
chr14_+_24584009	0.605		DCAF11	DDB1 and CUL4 associated factor 11
chr11_-_85397215	0.604	NM_152723	CCDC89	coiled-coil domain containing 89
chr6_-_31239489	0.603		HLA-B HLA-C	major histocompatibility complex, class I, B major histocompatibility complex, class I, C
chr6_+_16129285	0.596	NM_013262	MYLIP	myosin regulatory light chain interacting protein
chr14_+_24583979	0.592	NM_025230	DCAF11	DDB1 and CUL4 associated factor 11
chr6_+_29910308	0.591		HLA-A	major histocompatibility complex, class I, A
chr12_+_55248298	0.587	NM_058173	MUCL1	mucin-like 1
chr6_+_26217145	0.585	NM_021052	HIST1H2AE	histone cluster 1, H2ae
chr18_-_59854215	0.582		PIGN	phosphatidylinositol glycan anchor biosynthesis, class N
chr1_+_149858466	0.581	NM_003517	HIST2H2AC	histone cluster 2, H2ac
chr1_-_38397417	0.577		INPP5B	inositol polyphosphate-5-phosphatase, 75kDa
chr6_-_46620229	0.577	NM_016593	CYP39A1	cytochrome P450, family 39, subfamily A, polypeptide 1
chrX_+_9431314	0.573	NM_001139466 NM_001139467 NM_001139468	TBL1X	transducin (beta)-like 1X-linked
chr16_+_19078916	0.558	NM_016138	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_181429711	0.555	NM_003106	SOX2	SRY (sex determining region Y)-box 2
chr19_+_39882018	0.554		MED29	mediator complex subunit 29
chrY_+_14813159	0.553	NM_004654	USP9Y	ubiquitin specific peptidase 9, Y-linked
chr5_+_172483285	0.550	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr9_-_3223007	0.545
chr6_-_26271588	0.545	NM_003534	HIST1H3G	histone cluster 1, H3g
chr19_+_9434447	0.543	NM_001202406 NM_001202407 NM_001202408 NM_001202409 NM_001202410 NM_001202411 NM_032497	ZNF559	zinc finger protein 559
chr4_-_84035908	0.540	NM_001130715 NM_016619	PLAC8	placenta-specific 8
chr6_+_31430955	0.539		HCP5	HLA complex P5 (non-protein coding)
chr7_+_77325729	0.537	NM_198467	RSBN1L	round spermatid basic protein 1-like
chrX_+_69674914	0.534	NM_001166278	DLG3	discs, large homolog 3 (Drosophila)
chr14_+_64971504	0.533		ZBTB1	zinc finger and BTB domain containing 1
chr14_+_24583905	0.530	NM_001163484	DCAF11	DDB1 and CUL4 associated factor 11
chr6_-_167040506	0.530		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_15091441	0.529	NM_152321	ERP27	endoplasmic reticulum protein 27
chr1_+_164528586	0.528	NM_001204961 NM_001204963 NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr13_+_97928196	0.527		MBNL2	muscleblind-like 2 (Drosophila)
chr5_-_75013209	0.521	NM_001099271	POC5	POC5 centriolar protein homolog (Chlamydomonas)
chr5_+_140186658	0.520	NM_018907 NM_031500	PCDHA4	protocadherin alpha 4
chr14_+_23938883	0.513	NM_001042635 NM_015514	NGDN	neuroguidin, EIF4E binding protein
chr3_-_148804122	0.507	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr16_+_57769667	0.504		KATNB1	katanin p80 (WD repeat containing) subunit B 1
chr17_+_57408907	0.503	NM_001005404	YPEL2	yippee-like 2 (Drosophila)
chr1_+_12806162	0.495	NM_152290	C1orf158	chromosome 1 open reading frame 158
chr1_+_118148668	0.494		FAM46C	family with sequence similarity 46, member C
chr1_+_6845381	0.490	NM_001195563 NM_001242701 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr8_-_79717540	0.485	NM_000880 NM_001199886 NM_001199887 NM_001199888	IL7	interleukin 7
chr3_-_148939784	0.480	NM_000096	CP	ceruloplasmin (ferroxidase)
chr16_+_82068830	0.477	NM_002153	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr18_+_32073343	0.476		DTNA	dystrobrevin, alpha
chr19_+_39881950	0.472	NM_017592	MED29	mediator complex subunit 29
chr3_-_149510609	0.469	NM_001144960	ANKUB1	ankyrin repeat and ubiquitin domain containing 1
chr6_-_31324898	0.467		HLA-B	major histocompatibility complex, class I, B
chr14_-_75530716	0.467	NM_001107 NM_203488	ACYP1	acylphosphatase 1, erythrocyte (common) type
chr1_+_14075917	0.466		PRDM2	PR domain containing 2, with ZNF domain
chr6_-_42713822	0.459		TBCC	tubulin folding cofactor C
chr10_-_72142344	0.458	NM_018205 NM_018239	LRRC20	leucine rich repeat containing 20
chr15_-_86338017	0.453		KLHL25	kelch-like 25 (Drosophila)
chr1_+_104292439	0.451	NM_004038 NM_001008218 NM_001008219	AMY1A AMY1B AMY1C	amylase, alpha 1A (salivary) amylase, alpha 1B (salivary) amylase, alpha 1C (salivary)
chr5_+_142149970	0.447		ARHGAP26	Rho GTPase activating protein 26
chr14_+_23938902	0.443		NGDN	neuroguidin, EIF4E binding protein
chr1_+_14075861	0.430	NM_001007257	PRDM2	PR domain containing 2, with ZNF domain
chr4_+_69681709	0.429	NM_001075 NM_001144767	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_-_174829951	0.426		SP3	Sp3 transcription factor
chr1_+_151227209	0.424		PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr1_+_226250413	0.423		H3F3A	H3 histone, family 3A
chr14_-_58764805	0.423		FLJ31306	uncharacterized LOC379025
chr8_-_38008332	0.418	NM_000349	STAR	steroidogenic acute regulatory protein
chr7_-_95225802	0.411	NM_002612	PDK4	pyruvate dehydrogenase kinase, isozyme 4
chr6_+_135502445	0.409	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr8_+_107738239	0.408	NM_001198534 NM_001198535	OXR1	oxidation resistance 1
chr5_+_67511601	0.406		PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr14_-_74551073	0.403		ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr2_+_200323088	0.403
chr7_+_21467572	0.401	NM_003112	SP4	Sp4 transcription factor
chr6_+_31783280	0.401	NM_005345	HSPA1A	heat shock 70kDa protein 1A
chr14_-_91526912	0.399	NM_004755 NM_182398	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr1_-_183560010	0.394	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr16_+_15031299	0.394	NM_006985	NPIP	nuclear pore complex interacting protein
chr16_+_639668	0.390	NM_001172664	RAB40C	RAB40C, member RAS oncogene family
chr1_-_28241233	0.389	NM_002946	RPA2	replication protein A2, 32kDa
chr22_+_29138018	0.388	NM_172002	HSCB	HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr6_-_33041266	0.385	NM_033554	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1
chr6_-_31324955	0.383		HLA-B	major histocompatibility complex, class I, B
chr2_+_24807345	0.383	NM_003743 NM_147223 NM_147233	NCOA1	nuclear receptor coactivator 1
chr13_+_24734788	0.381	NM_001166271 NM_153023	SPATA13	spermatogenesis associated 13
chr5_-_89705477	0.380	NM_004365	CETN3	centrin, EF-hand protein, 3
chr16_+_82068910	0.377		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr6_+_31783314	0.371		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr1_-_228645517	0.371	NM_033445	HIST3H2A	histone cluster 3, H2a
chr19_+_41770273	0.366		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr7_+_105603656	0.365	NM_152750	CDHR3	cadherin-related family member 3
chr17_-_73511626	0.365	NM_020753	CASKIN2	CASK interacting protein 2
chr9_-_124989755	0.364	NM_001242334	LHX6	LIM homeobox 6
chr12_+_121124958	0.362		MLEC	malectin
chr1_+_15990300	0.362
chr6_+_16129321	0.358		MYLIP	myosin regulatory light chain interacting protein
chr9_-_84304378	0.353		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr16_+_19079220	0.345	NM_001190983	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr1_+_161136180	0.343	NM_000309 NM_001122764	PPOX	protoporphyrinogen oxidase
chr6_-_26235160	0.341	NM_005320	HIST1H1D	histone cluster 1, H1d
chr1_+_151227188	0.340	NM_002810	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr19_+_41430123	0.338		CYP2B7P1	cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr9_+_1050333	0.338	NM_006557 NM_001130865	DMRT2	doublesex and mab-3 related transcription factor 2
chr12_+_58138663	0.337	NM_005981	TSPAN31	tetraspanin 31
chr3_-_52931341	0.337		TMEM110	transmembrane protein 110
chr8_+_98788014	0.334		LAPTM4B	lysosomal protein transmembrane 4 beta

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.13	4.11e-05	GO:0065004	protein-DNA complex assembly
4.86	9.52e-05	GO:0071824	protein-DNA complex subunit organization
4.95	4.44e-04	GO:0031497	chromatin assembly
4.87	1.35e-03	GO:0006334	nucleosome assembly
4.03	1.48e-03	GO:0006333	chromatin assembly or disassembly
4.39	4.80e-03	GO:0034728	nucleosome organization
1.68	6.00e-03	GO:0006996	organelle organization
2.39	6.95e-03	GO:0006325	chromatin organization
2.18	7.77e-03	GO:0051276	chromosome organization
3.78	1.43e-02	GO:0006323	DNA packaging
1.47	1.85e-02	GO:0071842	cellular component organization at cellular level
3.46	2.26e-02	GO:0071103	DNA conformation change
2.47	3.06e-02	GO:0034622	cellular macromolecular complex assembly
1.45	3.27e-02	GO:0071841	cellular component organization or biogenesis at cellular level

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.21	5.19e-06	GO:0043229	intracellular organelle
1.20	6.66e-06	GO:0043226	organelle
1.23	8.26e-06	GO:0043231	intracellular membrane-bounded organelle
1.23	9.49e-06	GO:0043227	membrane-bounded organelle
6.40	7.01e-05	GO:0000786	nucleosome
1.32	1.25e-04	GO:0005634	nucleus
1.31	1.63e-04	GO:0044422	organelle part
1.14	2.47e-04	GO:0044424	intracellular part
1.31	3.25e-04	GO:0044446	intracellular organelle part
4.72	3.63e-04	GO:0032993	protein-DNA complex
1.13	3.84e-04	GO:0005622	intracellular
1.56	6.48e-04	GO:0070013	intracellular organelle lumen
1.54	8.99e-04	GO:0043233	organelle lumen
1.53	1.07e-03	GO:0031974	membrane-enclosed lumen
1.60	1.48e-03	GO:0031981	nuclear lumen
1.54	2.03e-03	GO:0044428	nuclear part
2.78	9.44e-03	GO:0000785	chromatin
2.08	1.19e-02	GO:0005694	chromosome
2.74	1.21e-02	GO:0005792	microsome
1.64	1.45e-02	GO:0005654	nucleoplasm
2.65	1.93e-02	GO:0042598	vesicular fraction

Nothing significant found in function category.