Motif ID: POU5F1.p2

Z-value: 0.922


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_311346140.346.9e-02Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_67410825 2.344 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr20_-_7921068 2.143 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr12_-_57634474 1.902 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr7_+_141463896 1.704 NM_016943
TAS2R3
taste receptor, type 2, member 3
chr3_-_123603144 1.516 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr11_-_115088628 1.309 CADM1
cell adhesion molecule 1
chr2_-_119605758 1.291 NM_001426
EN1
engrailed homeobox 1
chr11_-_115375065 1.284 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr2_+_210444364 1.158 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr17_-_41276112 1.128 NM_007298
BRCA1
breast cancer 1, early onset
chr8_+_26435339 1.084 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr12_-_16757944 1.029 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_17575592 1.028 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr8_-_23712297 1.013 NM_003155
STC1
stanniocalcin 1
chr13_-_60325073 1.001


chr12_+_107712151 0.961 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr6_+_31126734 0.954 TCF19
transcription factor 19
chr10_+_91498724 0.930 KIF20B
kinesin family member 20B
chr3_+_158787040 0.923 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr12_+_7942025 0.903 NANOG
Nanog homeobox
chr3_-_57234279 0.873 NM_003865
HESX1
HESX homeobox 1
chr20_+_361938 0.870 TRIB3
tribbles homolog 3 (Drosophila)
chr1_+_24840800 0.828 NM_001251980
NM_001251982
NM_001251985
RCAN3


RCAN family member 3


chr10_-_98031154 0.800 NM_001114094
NM_013314
BLNK

B-cell linker

chr8_-_72268720 0.781 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr8_+_26435466 0.779 DPYSL2
dihydropyrimidinase-like 2
chr3_-_64211111 0.764 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr11_-_568419 0.758 MIR210HG
MIR210 host gene (non-protein coding)
chr17_-_36105005 0.753 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr6_-_26124130 0.737 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr1_-_68962679 0.714 DEPDC1
DEP domain containing 1
chr1_-_200589856 0.711 NM_014875
KIF14
kinesin family member 14
chr4_+_1902352 0.705 NM_133334
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr20_+_361675 0.704 TRIB3
tribbles homolog 3 (Drosophila)
chr10_+_115312777 0.699 NM_004132
HABP2
hyaluronan binding protein 2
chr7_-_56101830 0.680 PSPH
phosphoserine phosphatase
chr16_+_23690234 0.674 PLK1
polo-like kinase 1
chr15_-_80263460 0.673 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr1_+_116654375 0.672 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chrX_-_33357725 0.663 NM_000109
DMD
dystrophin
chr6_-_11232901 0.661 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr18_+_47088400 0.660 NM_006033
LIPG
lipase, endothelial
chr11_-_3663484 0.650 NM_053017
NM_001079536
ART5

ADP-ribosyltransferase 5

chr2_+_210444154 0.647 MAP2
microtubule-associated protein 2
chr21_-_32201926 0.644 NM_181606
KRTAP7-1
keratin associated protein 7-1 (gene/pseudogene)
chr11_-_10673832 0.642 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr12_-_16758312 0.638 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_27695543 0.627 PBK
PDZ binding kinase
chr20_+_361272 0.619 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr8_+_25316714 0.618 CDCA2
cell division cycle associated 2
chr4_-_139163222 0.614 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chrX_-_80457440 0.608 NM_030763
HMGN5
high mobility group nucleosome binding domain 5
chr16_+_23690212 0.607 PLK1
polo-like kinase 1
chr5_+_126112819 0.605 NM_001198557
LMNB1
lamin B1
chr6_-_11232883 0.603 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr2_-_192015934 0.596 NM_003151
STAT4
signal transducer and activator of transcription 4
chr1_-_217262946 0.590 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr12_-_95945226 0.587 NM_032147
USP44
ubiquitin specific peptidase 44
chr2_-_192015706 0.587 STAT4
signal transducer and activator of transcription 4
chr5_+_126112847 0.586 LMNB1
lamin B1
chr1_-_68962726 0.577 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr13_-_103054027 0.565 NM_175929
FGF14
fibroblast growth factor 14
chr1_-_153044083 0.565 NM_001017418
SPRR2B
small proline-rich protein 2B
chr3_-_150690785 0.563 NM_001195794
NM_174878
CLRN1

clarin 1

chr1_-_217263195 0.557 NM_001243505
ESRRG
estrogen-related receptor gamma
chr2_+_233734993 0.556 NM_206895
C2orf82
chromosome 2 open reading frame 82
chr9_-_35079751 0.553 NM_004629
FANCG
Fanconi anemia, complementation group G
chr1_-_153013593 0.553 NM_006945
SPRR2D
small proline-rich protein 2D
chr11_-_102496049 0.551 NM_004771
MMP20
matrix metallopeptidase 20
chr2_-_113594325 0.545 NM_000576
IL1B
interleukin 1, beta
chr6_-_131291480 0.545 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_+_63428752 0.537 NM_144642
SYNPR
synaptoporin
chr6_-_114384008 0.532 NM_153612
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr12_-_16760935 0.532 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr7_+_94292737 0.523 PEG10
paternally expressed 10
chr9_-_124990706 0.522 NM_001242333
LHX6
LIM homeobox 6
chr2_+_174219537 0.521 NM_031942
NM_145810
CDCA7

cell division cycle associated 7

chr12_+_7941994 0.517 NM_024865
NANOG
Nanog homeobox
chr17_-_38859976 0.516 NM_019016
KRT24
keratin 24
chr1_-_247921707 0.514 NM_012353
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr1_+_6052758 0.513 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_+_6052699 0.512 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr8_-_122653493 0.508 NM_005328
HAS2
hyaluronan synthase 2
chr2_-_192015751 0.502 STAT4
signal transducer and activator of transcription 4
chr8_+_25316736 0.501 CDCA2
cell division cycle associated 2
chr11_+_131240370 0.499 NM_001048209
NTM
neurotrimin
chr18_+_42260774 0.496 NM_015559
SETBP1
SET binding protein 1
chr11_-_62369250 0.495 NM_004739
MTA2
metastasis associated 1 family, member 2
chr2_+_29038862 0.494 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr1_+_174417211 0.491 NM_005684
GPR52
G protein-coupled receptor 52
chr22_+_22735202 0.489


chr6_-_11232900 0.488 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr11_-_31832592 0.487 PAX6
paired box 6
chr5_-_146833150 0.481 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr1_+_214776582 0.481 CENPF
centromere protein F, 350/400kDa (mitosin)
chr13_+_109281569 0.478 NM_001198950
MYO16
myosin XVI
chr16_+_23690190 0.475 PLK1
polo-like kinase 1
chr11_-_119599253 0.470 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr14_+_62462540 0.469 NM_031914
SYT16
synaptotagmin XVI
chr16_+_23690191 0.469 NM_005030
PLK1
polo-like kinase 1
chr21_-_36252872 0.468 RUNX1
runt-related transcription factor 1
chr10_+_106113513 0.466 NM_001008723
CCDC147
coiled-coil domain containing 147
chr20_+_9494995 0.464 NM_001199897
NM_012261
LAMP5

lysosomal-associated membrane protein family, member 5

chr16_+_23847321 0.463 PRKCB
protein kinase C, beta
chr11_-_31832758 0.458 PAX6
paired box 6
chr11_-_62369213 0.457 MTA2
metastasis associated 1 family, member 2
chr19_-_55919324 0.457 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr8_-_72274466 0.456 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_83824216 0.454 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_7818467 0.450 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr3_+_6902797 0.449 NM_000844
NM_181874
GRM7

glutamate receptor, metabotropic 7

chr22_+_38035683 0.448 NM_018957
SH3BP1
SH3-domain binding protein 1
chr12_-_8043743 0.444 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr12_-_16759430 0.444 LMO3
LIM domain only 3 (rhombotin-like 2)
chr15_+_67358161 0.443 SMAD3
SMAD family member 3
chr3_-_71294229 0.443 NM_001244814
FOXP1
forkhead box P1
chr11_-_62369097 0.443 MTA2
metastasis associated 1 family, member 2
chr12_-_16759531 0.443 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_-_42419782 0.441 NM_033502
TRERF1
transcriptional regulating factor 1
chr13_-_30881141 0.441 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr20_-_54967221 0.441 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr11_-_31832784 0.439 PAX6
paired box 6
chr19_-_36004553 0.435 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr1_-_153029987 0.434 NM_005988
SPRR2A
small proline-rich protein 2A
chr16_+_3405888 0.432 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr7_+_31003635 0.432 NM_000823
GHRHR
growth hormone releasing hormone receptor
chr11_-_28129646 0.430 KIF18A
kinesin family member 18A
chrX_+_22050920 0.429 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr20_+_44441334 0.423 UBE2C
ubiquitin-conjugating enzyme E2C
chr12_-_16759733 0.422 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_+_7589388 0.421 NM_001143990
WRAP53
WD repeat containing, antisense to TP53
chr2_+_74120092 0.420 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr22_-_46449972 0.420 NM_018280
C22orf26
chromosome 22 open reading frame 26
chr10_+_94352960 0.419 KIF11
kinesin family member 11
chr17_-_46692300 0.417 NM_024016
HOXB8
homeobox B8
chr19_+_6135650 0.408 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr9_-_124990949 0.408 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr7_+_36429388 0.404 NM_018685
ANLN
anillin, actin binding protein
chr9_+_35732498 0.399 CREB3
cAMP responsive element binding protein 3
chr12_+_28410132 0.397 NM_018318
CCDC91
coiled-coil domain containing 91
chr5_-_39270708 0.390 NM_001243093
FYB
FYN binding protein
chr6_+_55039070 0.389 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr7_+_18535351 0.388 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr12_-_11286842 0.387 NM_001097643
TAS2R30
taste receptor, type 2, member 30
chr2_+_74120132 0.386 ACTG2
actin, gamma 2, smooth muscle, enteric
chrY_+_16635625 0.385 NM_014893
NLGN4Y
neuroligin 4, Y-linked
chr17_-_37381920 0.384 NM_198993
STAC2
SH3 and cysteine rich domain 2
chr4_-_164534656 0.383 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr1_+_38158189 0.380 CDCA8
cell division cycle associated 8
chr5_-_59995938 0.378 NM_001145208
NM_018369
DEPDC1B

DEP domain containing 1B

chr8_-_134115309 0.378 NM_001045556
NM_001045557
SLA

Src-like-adaptor

chr16_+_23690160 0.373 PLK1
polo-like kinase 1
chr19_+_50169080 0.372 BCL2L12
BCL2-like 12 (proline rich)
chr6_+_80714389 0.369 TTK
TTK protein kinase
chr3_+_46395224 0.368 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr6_+_163984574 0.367 QKI
QKI, KH domain containing, RNA binding
chr4_-_95263986 0.360 NM_014485
HPGDS
hematopoietic prostaglandin D synthase
chr14_-_94442894 0.360 ASB2
ankyrin repeat and SOCS box containing 2
chr5_-_13944588 0.360 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr22_+_22758538 0.359


chr12_-_16759939 0.359 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_41742666 0.357 NM_002192
INHBA
inhibin, beta A
chr2_+_54785453 0.357 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr5_-_39203061 0.353 FYB
FYN binding protein
chr2_-_50574891 0.352 NM_138735
NRXN1
neurexin 1
chr3_-_112359547 0.348 CCDC80
coiled-coil domain containing 80
chr2_+_90077732 0.344


chr10_+_95256348 0.343 NM_001127182
NM_018131
CEP55

centrosomal protein 55kDa

chr14_+_32798478 0.340 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr6_+_34204647 0.338 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr20_+_56136136 0.337 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chrY_+_16634487 0.337 NM_001206850
NLGN4Y
neuroligin 4, Y-linked
chr3_+_158991035 0.336 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr10_+_91461333 0.333 NM_016195
KIF20B
kinesin family member 20B
chr10_+_77542518 0.329 NM_032024
C10orf11
chromosome 10 open reading frame 11
chrX_-_132095422 0.328 NM_001077188
NM_147175
HS6ST2

heparan sulfate 6-O-sulfotransferase 2

chr15_-_22473092 0.327


chr4_+_184020343 0.326 NM_024949
WWC2
WW and C2 domain containing 2
chr9_+_35732207 0.326 NM_006368
CREB3
cAMP responsive element binding protein 3
chr12_-_102591547 0.325 NM_002674
PMCH
pro-melanin-concentrating hormone
chr16_+_31366519 0.325 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr10_+_49609641 0.320 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr1_+_32538497 0.318 NM_018056
TMEM39B
transmembrane protein 39B
chr12_+_111471827 0.317 NM_015267
CUX2
cut-like homeobox 2
chr14_-_107013122 0.315 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_+_105953531 0.312 CRIP1
cysteine-rich protein 1 (intestinal)
chr1_+_179575361 0.310 NM_001199092
TDRD5
tudor domain containing 5
chr11_-_28129687 0.309 KIF18A
kinesin family member 18A
chr20_+_44441247 0.308 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr6_+_34204663 0.307 HMGA1
high mobility group AT-hook 1
chr3_-_149086884 0.305 TM4SF1
transmembrane 4 L six family member 1
chr6_+_34205029 0.299 HMGA1
high mobility group AT-hook 1
chr20_+_17207680 0.297 PCSK2
proprotein convertase subtilisin/kexin type 2
chr14_-_57272344 0.297 NM_172337
OTX2
orthodenticle homeobox 2
chr11_+_77774902 0.296 NM_003251
THRSP
thyroid hormone responsive
chr22_+_38035718 0.295 SH3BP1
SH3-domain binding protein 1
chr11_-_95657255 0.294 NM_001243571
NM_016156
NM_201278
NM_201281
MTMR2



myotubularin related protein 2



chr4_+_88896868 0.293 SPP1
secreted phosphoprotein 1
chr15_+_59397276 0.292 NM_004701
CCNB2
cyclin B2
chr6_+_47749774 0.291 NM_181744
OPN5
opsin 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.47 1.07e-16 GO:0032502 developmental process
1.26 1.48e-16 GO:0065007 biological regulation
1.52 3.49e-16 GO:0048856 anatomical structure development
1.54 2.10e-15 GO:0048731 system development
1.47 3.34e-15 GO:0007275 multicellular organismal development
1.26 7.70e-15 GO:0050789 regulation of biological process
1.28 9.54e-15 GO:0050794 regulation of cellular process
1.34 3.85e-14 GO:0032501 multicellular organismal process
1.75 2.69e-13 GO:0007399 nervous system development
1.14 1.73e-11 GO:0009987 cellular process
1.56 7.94e-11 GO:0030154 cell differentiation
1.55 1.15e-10 GO:0048869 cellular developmental process
1.56 1.25e-09 GO:0048513 organ development
1.36 1.78e-09 GO:0023052 signaling
1.84 2.32e-09 GO:0022008 neurogenesis
1.37 1.50e-08 GO:0060255 regulation of macromolecule metabolic process
1.35 4.63e-08 GO:0080090 regulation of primary metabolic process
1.36 6.48e-08 GO:0007165 signal transduction
1.32 8.87e-08 GO:0019222 regulation of metabolic process
1.31 1.83e-07 GO:0051716 cellular response to stimulus
1.34 2.04e-07 GO:0031323 regulation of cellular metabolic process
1.23 2.32e-07 GO:0050896 response to stimulus
1.46 2.50e-07 GO:0048523 negative regulation of cellular process
1.88 2.50e-07 GO:0030182 neuron differentiation
1.44 3.66e-07 GO:0051252 regulation of RNA metabolic process
1.77 4.79e-07 GO:0048699 generation of neurons
1.45 5.71e-07 GO:0006355 regulation of transcription, DNA-dependent
1.39 7.02e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.71 7.32e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.42 7.85e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.40 8.26e-07 GO:0010468 regulation of gene expression
1.38 1.58e-06 GO:0009889 regulation of biosynthetic process
1.38 1.72e-06 GO:0031326 regulation of cellular biosynthetic process
1.37 2.20e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.38 2.83e-06 GO:0071842 cellular component organization at cellular level
1.70 4.87e-06 GO:0048468 cell development
1.39 5.04e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.32 5.43e-06 GO:0016043 cellular component organization
1.97 5.55e-06 GO:0007417 central nervous system development
1.40 9.43e-06 GO:0048519 negative regulation of biological process
1.51 1.36e-05 GO:0009653 anatomical structure morphogenesis
1.36 1.51e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.87 1.60e-05 GO:0048666 neuron development
1.30 2.53e-05 GO:0071840 cellular component organization or biogenesis
1.38 4.89e-05 GO:0042221 response to chemical stimulus
1.79 7.01e-05 GO:0030030 cell projection organization
1.34 8.32e-05 GO:0048518 positive regulation of biological process
1.79 8.67e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.74 1.38e-04 GO:0010628 positive regulation of gene expression
1.90 1.59e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.95 1.81e-04 GO:0007409 axonogenesis
1.85 3.74e-04 GO:0031175 neuron projection development
1.57 4.26e-04 GO:0009605 response to external stimulus
1.83 5.34e-04 GO:0032990 cell part morphogenesis
1.88 6.67e-04 GO:0048812 neuron projection morphogenesis
1.61 6.79e-04 GO:0040011 locomotion
1.88 7.33e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.33 7.35e-04 GO:0048522 positive regulation of cellular process
1.82 7.73e-04 GO:0048858 cell projection morphogenesis
1.80 9.93e-04 GO:0006935 chemotaxis
1.80 9.93e-04 GO:0042330 taxis
1.69 1.20e-03 GO:0051254 positive regulation of RNA metabolic process
1.53 1.31e-03 GO:0010646 regulation of cell communication
4.11 1.44e-03 GO:0050909 sensory perception of taste
1.67 1.56e-03 GO:0031327 negative regulation of cellular biosynthetic process
4.02 2.08e-03 GO:0048663 neuron fate commitment
1.62 2.87e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 3.52e-03 GO:0007166 cell surface receptor linked signaling pathway
1.60 3.63e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.52 3.74e-03 GO:0007154 cell communication
1.69 3.84e-03 GO:0009887 organ morphogenesis
1.64 3.96e-03 GO:0009890 negative regulation of biosynthetic process
1.61 4.13e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.68 4.14e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.76 4.97e-03 GO:0000904 cell morphogenesis involved in differentiation
1.56 5.67e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.55 7.31e-03 GO:0009891 positive regulation of biosynthetic process
1.66 8.67e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.41 9.40e-03 GO:0045165 cell fate commitment
1.58 1.09e-02 GO:2000026 regulation of multicellular organismal development
1.64 1.36e-02 GO:0032989 cellular component morphogenesis
1.85 1.39e-02 GO:0007420 brain development
1.53 1.50e-02 GO:0006351 transcription, DNA-dependent
1.61 1.52e-02 GO:0045595 regulation of cell differentiation
1.51 1.88e-02 GO:0050793 regulation of developmental process
1.63 1.88e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.64 2.01e-02 GO:0000902 cell morphogenesis
1.36 2.28e-02 GO:0023051 regulation of signaling
1.77 2.69e-02 GO:0009968 negative regulation of signal transduction
1.42 2.81e-02 GO:0009893 positive regulation of metabolic process
1.44 2.86e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.43 3.16e-02 GO:0031325 positive regulation of cellular metabolic process
1.59 3.34e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.21 3.36e-02 GO:0030900 forebrain development
1.80 3.43e-02 GO:0009792 embryo development ending in birth or egg hatching
1.73 3.76e-02 GO:0023057 negative regulation of signaling
1.72 4.08e-02 GO:0010648 negative regulation of cell communication
1.47 4.12e-02 GO:0032879 regulation of localization
1.68 4.18e-02 GO:0048585 negative regulation of response to stimulus
1.84 4.75e-02 GO:0007411 axon guidance
5.24 4.88e-02 GO:0048665 neuron fate specification
1.79 4.94e-02 GO:0043009 chordate embryonic development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 2.72e-06 GO:0005634 nucleus
1.39 7.85e-04 GO:0005856 cytoskeleton
1.82 9.38e-04 GO:0043005 neuron projection
2.14 7.25e-03 GO:0030424 axon
1.46 1.53e-02 GO:0042995 cell projection
1.23 3.26e-02 GO:0043228 non-membrane-bounded organelle
1.23 3.26e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.38 4.20e-02 GO:0044430 cytoskeletal part
1.52 4.95e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.82 6.28e-11 GO:0001071 nucleic acid binding transcription factor activity
1.82 6.28e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
2.01 7.38e-11 GO:0043565 sequence-specific DNA binding
1.11 5.56e-08 GO:0005488 binding
1.68 1.13e-07 GO:0030528 transcription regulator activity
1.19 2.78e-07 GO:0005515 protein binding
2.08 3.25e-05 GO:0003779 actin binding
1.34 1.09e-04 GO:0003677 DNA binding
6.63 8.18e-04 GO:0008527 taste receptor activity
1.63 9.23e-03 GO:0008092 cytoskeletal protein binding
1.83 1.15e-02 GO:0016563 transcription activator activity
1.22 1.19e-02 GO:0003676 nucleic acid binding
1.97 4.14e-02 GO:0000975 regulatory region DNA binding
1.97 4.14e-02 GO:0001067 regulatory region nucleic acid binding
1.97 4.14e-02 GO:0044212 transcription regulatory region DNA binding