Motif ID: RREB1.p2

Z-value: 2.424


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RREB1chr6_+_71077990.365.1e-02Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_152486073 7.412 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr10_-_135150474 6.816 NM_015722
CALY
calcyon neuron-specific vesicular protein
chrX_+_151903218 6.523 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chr10_-_135150368 5.139 CALY
calcyon neuron-specific vesicular protein
chr19_-_55658310 4.696 TNNT1
troponin T type 1 (skeletal, slow)
chr7_-_752083 4.341 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr6_-_30654406 4.179 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr11_-_125366048 3.770 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr3_-_48632592 3.747 NM_000094
COL7A1
collagen, type VII, alpha 1
chr21_-_47604360 3.671 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr21_-_47604340 3.604 C21orf56
chromosome 21 open reading frame 56
chr21_-_47604300 3.562 C21orf56
chromosome 21 open reading frame 56
chr19_-_51456159 3.448 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr2_-_216300770 3.383 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr3_-_106959476 3.321


chr22_-_43583132 3.309 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr8_+_86376130 3.052 NM_000067
CA2
carbonic anhydrase II
chr22_-_43583058 2.867 TTLL12
tubulin tyrosine ligase-like family, member 12
chr5_-_136834887 2.753 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chrX_-_153881757 2.701 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chr12_-_122231554 2.671 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr19_-_55660557 2.642 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr2_-_31352489 2.641 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr7_+_44143945 2.638 NM_001129
AEBP1
AE binding protein 1
chr21_-_44495894 2.593 NM_000071
CBS
cystathionine-beta-synthase
chr3_+_50654589 2.573 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr12_+_70759974 2.554 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr1_+_32043745 2.529 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr7_+_44144002 2.461 AEBP1
AE binding protein 1
chr3_-_15140623 2.457 ZFYVE20
zinc finger, FYVE domain containing 20
chr6_-_109776832 2.390 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr6_+_151561653 2.329 AKAP12
A kinase (PRKA) anchor protein 12
chr6_-_109776942 2.326 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr1_-_17307107 2.321 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr7_-_767286 2.319 NM_001164758
NM_001164759
PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

chrX_-_151903100 2.303 NM_001166386
NM_001166387
NM_005367
MAGEA12


melanoma antigen family A, 12


chr19_-_19052032 2.296 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr4_+_191008565 2.262 NM_012147
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX2
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr6_-_109776946 2.253 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr19_-_19051899 2.244 HOMER3
homer homolog 3 (Drosophila)
chr1_-_236030170 2.234


chr11_-_59436366 2.183 PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr21_-_45682098 2.170 NM_013369
NM_175867
DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

chr9_+_139560243 2.167 EGFL7
EGF-like-domain, multiple 7
chr16_-_4588379 2.162 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr5_+_156887204 2.120 NIPAL4
NIPA-like domain containing 4
chr3_+_50654558 2.119 NM_001243925
NM_004635
MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3

chr2_-_128432642 2.102 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chrX_+_151867244 2.099 NM_005363
NM_175868
MAGEA2
MAGEA6

melanoma antigen family A, 2
melanoma antigen family A, 6

chr7_-_766875 2.098 NM_001164760
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr18_-_21242592 2.096 NM_173505
ANKRD29
ankyrin repeat domain 29
chr1_+_1950745 2.092 NM_000815
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr7_-_27135524 2.092 NM_005522
NM_153620
HOXA1

homeobox A1

chr14_+_105173953 2.091 INF2
inverted formin, FH2 and WH2 domain containing
chr17_+_70117168 2.091 SOX9
SRY (sex determining region Y)-box 9
chr6_-_109777085 2.079 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr1_+_1076275 2.041 LOC254099
uncharacterized LOC254099
chr4_+_190998678 2.038 NM_012147
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX2
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr19_-_15343767 2.028 NM_001142886
EPHX3
epoxide hydrolase 3
chr1_-_20812727 2.020 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_+_70117154 2.007 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chrX_+_153813417 2.001 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr6_+_151646634 1.994 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr9_+_35906188 1.947 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr4_+_191001978 1.947 NM_001177376
DUX4L4
double homeobox 4 like 4
chr9_-_123639462 1.929 PHF19
PHD finger protein 19
chr22_-_38794853 1.921 LOC400927
TPTE and PTEN homologous inositol lipid phosphatase pseudogene
chr17_-_76921205 1.916 TIMP2
TIMP metallopeptidase inhibitor 2
chr10_-_134145333 1.912 STK32C
serine/threonine kinase 32C
chr12_+_4382882 1.884 NM_001759
CCND2
cyclin D2
chr1_-_228604582 1.870 NM_001024940
NM_001134855
NM_016102
TRIM17


tripartite motif containing 17


chrX_+_17755562 1.869 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr5_+_92920592 1.867 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr17_-_76921076 1.861 TIMP2
TIMP metallopeptidase inhibitor 2
chr10_+_17271276 1.856 VIM
vimentin
chr11_+_57365026 1.852 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr11_+_72929392 1.848 NM_176071
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr7_-_102920665 1.827 DPY19L2P2
dpy-19-like 2 pseudogene 2 (C. elegans)
chr7_-_143059144 1.818 NM_014690
FAM131B
family with sequence similarity 131, member B
chr4_+_190992092 1.817 NM_001177376
NM_001127388
NM_001127389
NM_001164467
DUX4L4
DUX4L6
DUX4L5
DUX4L3
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
chr4_+_191011859 1.800 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_191005266 1.800 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_190995385 1.797 NM_012147
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX2
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr18_-_28681429 1.796 DSC2
desmocollin 2
chr12_-_48152860 1.780 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr3_+_50654600 1.775 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr6_-_109777171 1.775 NM_001159291
NM_022765
MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr2_-_128433330 1.768 LIMS2
LIM and senescent cell antigen-like domains 2
chr20_+_44637539 1.758 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr1_-_228604305 1.754 TRIM17
tripartite motif containing 17
chr2_-_224903933 1.746 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr10_+_135493659 1.735 NM_012147
DUX2
double homeobox 2
chr1_-_41131113 1.712 RIMS3
regulating synaptic membrane exocytosis 3
chr1_-_153348057 1.706 NM_005621
S100A12
S100 calcium binding protein A12
chr15_+_63335086 1.657 TPM1
tropomyosin 1 (alpha)
chr22_+_30792929 1.653 NM_001204204
NM_012429
NM_033382
SEC14L2


SEC14-like 2 (S. cerevisiae)


chr4_+_190988866 1.652 NM_012147
DUX2
double homeobox 2
chr10_+_135480367 1.638 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chrX_+_135229536 1.635 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr7_+_27135672 1.605 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr21_-_47648715 1.597 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr2_-_165477986 1.583 GRB14
growth factor receptor-bound protein 14
chr10_+_135483677 1.581 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr9_-_139890984 1.563 NM_004669
CLIC3
chloride intracellular channel 3
chr21_-_44496423 1.549 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr20_+_361938 1.541 TRIB3
tribbles homolog 3 (Drosophila)
chr7_-_102920840 1.541 DPY19L2P2
dpy-19-like 2 pseudogene 2 (C. elegans)
chr2_+_73144603 1.533 NM_004097
EMX1
empty spiracles homeobox 1
chr11_+_69455978 1.531 CCND1
cyclin D1
chr17_-_76124767 1.528 TMC6
transmembrane channel-like 6
chr10_+_135490278 1.523 NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr1_-_231175971 1.507 NM_198552
FAM89A
family with sequence similarity 89, member A
chr8_-_145047639 1.500 NM_201378
PLEC
plectin
chr9_-_123639566 1.492 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr15_-_74726000 1.489 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr1_-_154943001 1.486 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr1_+_16085245 1.478 NM_017556
FBLIM1
filamin binding LIM protein 1
chr2_+_30454396 1.474 NM_030915
LBH
limb bud and heart development homolog (mouse)
chrX_-_119249774 1.459 NM_139282
RHOXF1
Rhox homeobox family, member 1
chr2_-_228029274 1.452 NM_000092
COL4A4
collagen, type IV, alpha 4
chr16_+_66638212 1.446 NM_144601
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr11_-_34379526 1.434 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr12_+_6937570 1.433 NM_014262
LEPREL2
leprecan-like 2
chr8_-_121823696 1.433 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr3_-_13921617 1.431 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr14_+_24867926 1.417 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr7_-_20826503 1.416 NM_182700
NM_198956
SP8

Sp8 transcription factor

chr11_-_59436488 1.415 NM_152716
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr18_+_33877630 1.414 NM_025135
FHOD3
formin homology 2 domain containing 3
chr19_-_14049167 1.413 NM_024825
PODNL1
podocan-like 1
chr16_+_66638530 1.408 NM_181553
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr5_-_142065586 1.405 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr20_-_62103815 1.402 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr12_-_48152180 1.400 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr6_+_32121775 1.399 NM_001204103
NM_005155
PPT2-EGFL8
PPT2

PPT2-EGFL8 readthrough
palmitoyl-protein thioesterase 2

chr21_-_47648685 1.398 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr2_+_115919512 1.394 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr12_-_54785018 1.386 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr19_-_409169 1.382 NM_001136263
C2CD4C
C2 calcium-dependent domain containing 4C
chr4_-_111119752 1.376 NM_001130721
NM_024090
ELOVL6

ELOVL fatty acid elongase 6

chr16_-_4588738 1.375 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr17_-_76124791 1.375 NM_001127198
TMC6
transmembrane channel-like 6
chr21_-_47648618 1.375 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chrX_-_153847390 1.371 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr16_+_66638652 1.365 CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr21_-_44846927 1.359 NM_173354
SIK1
salt-inducible kinase 1
chrX_+_135230736 1.357 NM_001159700
FHL1
four and a half LIM domains 1
chr11_-_134281725 1.353 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr10_-_98945379 1.349 SLIT1
slit homolog 1 (Drosophila)
chr1_-_6557448 1.349 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_+_4776826 1.348 CDYL
chromodomain protein, Y-like
chr2_-_163695028 1.348 KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr3_+_50654868 1.339 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr11_+_57365577 1.337 NM_001032295
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr7_-_102257199 1.334 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr19_-_51504799 1.328 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chrX_-_100872926 1.317 NM_001009584
NM_001184768
NM_019007
ARMCX6


armadillo repeat containing, X-linked 6


chr19_-_51472003 1.316 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr10_+_120967094 1.313 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr11_-_72353435 1.310 NM_001143839
NM_001243784
PDE2A

phosphodiesterase 2A, cGMP-stimulated

chr19_-_14887623 1.305 EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr12_-_54982271 1.303 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr6_+_34204647 1.299 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr6_+_34204663 1.297 HMGA1
high mobility group AT-hook 1
chr19_+_54926721 1.292 TTYH1
tweety homolog 1 (Drosophila)
chr9_+_72658735 1.285 MAMDC2
MAM domain containing 2
chr8_-_60031545 1.284 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr17_+_7942351 1.281 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr20_-_50159037 1.280 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr19_-_8675559 1.279 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr21_-_28217692 1.275 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_-_161520412 1.274 NM_001127593
NM_001127595
NM_001127596
FCGR3A


Fc fragment of IgG, low affinity IIIa, receptor (CD16a)


chr7_+_143058794 1.270 ZYX
zyxin
chr22_-_17747520 1.253 CECR3
cat eye syndrome chromosome region, candidate 3 (non-protein coding)
chr22_+_44319685 1.253 PNPLA3
patatin-like phospholipase domain containing 3
chr21_-_47648672 1.249 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr7_-_128045995 1.241 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr20_+_35974458 1.240 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr12_+_79258794 1.232 SYT1
synaptotagmin I
chr7_-_28220342 1.232 NM_175061
JAZF1
JAZF zinc finger 1
chr16_+_56225301 1.225 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr7_-_752132 1.224 NM_002735
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr14_-_24047428 1.216 JPH4
junctophilin 4
chr16_+_46919101 1.215 NM_001142466
GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr20_-_50159247 1.203 NM_012340
NM_173091
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr19_+_17862285 1.200 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr13_+_47127312 1.195 LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr2_-_165477818 1.194 GRB14
growth factor receptor-bound protein 14
chr17_-_46655544 1.192 NM_024015
HOXB4
homeobox B4
chr7_-_102257135 1.189 RASA4
RAS p21 protein activator 4
chr14_+_93813536 1.188 NM_182971
COX8C
cytochrome c oxidase subunit VIIIC
chr6_-_48036385 1.186 NM_001013732
NM_207499
C6orf138

chromosome 6 open reading frame 138

chr12_-_12715244 1.185 NM_030640
DUSP16
dual specificity phosphatase 16
chr5_-_39424930 1.185 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_+_145718586 1.184 NM_002700
POU4F3
POU class 4 homeobox 3
chr1_-_85358851 1.182 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr16_+_81478774 1.181 NM_198390
CMIP
c-Maf inducing protein
chr21_+_45161343 1.181 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr3_+_12329332 1.177 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr14_-_94595925 1.174 NM_032036
IFI27L2
interferon, alpha-inducible protein 27-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 1.50e-22 GO:0032502 developmental process
1.40 3.78e-22 GO:0048731 system development
1.35 7.18e-22 GO:0007275 multicellular organismal development
1.37 2.08e-21 GO:0048856 anatomical structure development
1.55 2.40e-19 GO:0007399 nervous system development
1.17 5.43e-18 GO:0065007 biological regulation
1.30 3.44e-17 GO:0023052 signaling
1.42 1.05e-16 GO:0030154 cell differentiation
1.44 1.19e-16 GO:0048513 organ development
1.41 5.12e-16 GO:0048869 cellular developmental process
1.50 8.32e-16 GO:0009653 anatomical structure morphogenesis
1.70 1.37e-13 GO:0030182 neuron differentiation
1.63 1.45e-13 GO:0048699 generation of neurons
1.61 1.49e-13 GO:0022008 neurogenesis
1.16 1.54e-13 GO:0050789 regulation of biological process
1.44 2.87e-13 GO:0023051 regulation of signaling
1.17 7.06e-13 GO:0050794 regulation of cellular process
1.82 9.86e-13 GO:0019226 transmission of nerve impulse
1.82 9.86e-13 GO:0035637 multicellular organismal signaling
1.57 3.60e-12 GO:0048468 cell development
1.47 1.22e-11 GO:0051239 regulation of multicellular organismal process
1.30 1.51e-11 GO:0048518 positive regulation of biological process
1.53 1.79e-11 GO:0007154 cell communication
1.20 3.12e-11 GO:0032501 multicellular organismal process
1.26 3.70e-11 GO:0007165 signal transduction
1.55 5.41e-11 GO:0050793 regulation of developmental process
1.81 1.10e-10 GO:0007268 synaptic transmission
1.09 1.14e-10 GO:0009987 cellular process
1.31 1.18e-10 GO:0048522 positive regulation of cellular process
1.60 1.82e-10 GO:0007267 cell-cell signaling
1.31 2.37e-10 GO:0048519 negative regulation of biological process
1.33 4.72e-10 GO:0048523 negative regulation of cellular process
1.62 8.62e-10 GO:0045595 regulation of cell differentiation
1.67 1.33e-09 GO:0048666 neuron development
1.47 1.98e-09 GO:0010646 regulation of cell communication
1.40 2.63e-09 GO:0009966 regulation of signal transduction
1.56 4.60e-09 GO:2000026 regulation of multicellular organismal development
1.69 4.76e-09 GO:0007417 central nervous system development
1.70 7.23e-09 GO:0031175 neuron projection development
1.69 9.22e-09 GO:0000904 cell morphogenesis involved in differentiation
1.63 1.10e-08 GO:0009887 organ morphogenesis
1.33 1.11e-08 GO:0048583 regulation of response to stimulus
1.72 2.92e-08 GO:0048812 neuron projection morphogenesis
1.72 3.23e-08 GO:0048667 cell morphogenesis involved in neuron differentiation
1.20 3.38e-08 GO:0051716 cellular response to stimulus
1.73 3.92e-08 GO:0007409 axonogenesis
1.49 1.31e-07 GO:0009888 tissue development
1.80 1.75e-07 GO:0007411 axon guidance
1.37 4.20e-07 GO:0035556 intracellular signal transduction
1.28 4.23e-07 GO:0042221 response to chemical stimulus
1.74 5.21e-07 GO:0007420 brain development
2.08 7.07e-07 GO:0030900 forebrain development
1.61 1.03e-06 GO:0006935 chemotaxis
1.61 1.03e-06 GO:0042330 taxis
1.43 1.24e-06 GO:0032879 regulation of localization
1.56 1.28e-06 GO:0000902 cell morphogenesis
1.61 1.37e-06 GO:0009967 positive regulation of signal transduction
1.30 1.43e-06 GO:0007166 cell surface receptor linked signaling pathway
1.37 1.71e-06 GO:0009893 positive regulation of metabolic process
1.52 1.77e-06 GO:0010628 positive regulation of gene expression
1.27 2.52e-06 GO:0065008 regulation of biological quality
1.53 2.82e-06 GO:0032989 cellular component morphogenesis
1.45 2.98e-06 GO:0040011 locomotion
1.14 3.68e-06 GO:0050896 response to stimulus
1.20 4.12e-06 GO:0031323 regulation of cellular metabolic process
1.59 4.38e-06 GO:0048858 cell projection morphogenesis
1.74 4.90e-06 GO:0051093 negative regulation of developmental process
1.20 6.38e-06 GO:0080090 regulation of primary metabolic process
1.57 6.52e-06 GO:0023056 positive regulation of signaling
1.41 7.44e-06 GO:0009605 response to external stimulus
1.57 7.60e-06 GO:0010647 positive regulation of cell communication
1.18 8.39e-06 GO:0019222 regulation of metabolic process
1.58 8.50e-06 GO:0032990 cell part morphogenesis
1.51 9.17e-06 GO:0030030 cell projection organization
1.36 1.15e-05 GO:0031325 positive regulation of cellular metabolic process
1.46 1.23e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 1.78e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.46 2.19e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.45 2.19e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.51 2.22e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.39 3.33e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.48 4.11e-05 GO:0051254 positive regulation of RNA metabolic process
1.42 4.20e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.42 4.44e-05 GO:0009891 positive regulation of biosynthetic process
1.57 4.57e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.63 5.56e-05 GO:0010627 regulation of intracellular protein kinase cascade
1.77 5.92e-05 GO:0045596 negative regulation of cell differentiation
1.67 6.44e-05 GO:0044057 regulation of system process
1.71 2.37e-04 GO:0061061 muscle structure development
1.45 2.60e-04 GO:0042325 regulation of phosphorylation
1.40 3.57e-04 GO:0051128 regulation of cellular component organization
1.40 3.83e-04 GO:0048584 positive regulation of response to stimulus
1.70 3.93e-04 GO:0010740 positive regulation of intracellular protein kinase cascade
1.84 4.45e-04 GO:0043408 regulation of MAPKKK cascade
1.66 4.51e-04 GO:0022603 regulation of anatomical structure morphogenesis
2.04 4.87e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.18 5.40e-04 GO:0060255 regulation of macromolecule metabolic process
2.02 6.61e-04 GO:0022604 regulation of cell morphogenesis
1.42 8.49e-04 GO:0019220 regulation of phosphate metabolic process
1.42 8.49e-04 GO:0051174 regulation of phosphorus metabolic process
1.48 8.51e-04 GO:0051253 negative regulation of RNA metabolic process
1.43 1.03e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.62 1.15e-03 GO:0060284 regulation of cell development
1.44 1.25e-03 GO:0001932 regulation of protein phosphorylation
1.36 1.51e-03 GO:0009611 response to wounding
1.47 1.97e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.65 2.15e-03 GO:0051960 regulation of nervous system development
1.40 2.19e-03 GO:0051049 regulation of transport
1.51 2.32e-03 GO:0051094 positive regulation of developmental process
1.47 2.73e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.08 3.45e-03 GO:0043410 positive regulation of MAPKKK cascade
1.76 4.77e-03 GO:0007517 muscle organ development
1.19 4.92e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.87 5.38e-03 GO:0034330 cell junction organization
1.18 6.01e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.49 6.20e-03 GO:0008283 cell proliferation
1.52 6.62e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.48 6.97e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.67 8.90e-03 GO:0051129 negative regulation of cellular component organization
1.25 9.27e-03 GO:0065009 regulation of molecular function
1.40 9.46e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.38 9.74e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.40 1.11e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 1.25e-02 GO:0051270 regulation of cellular component movement
1.40 1.55e-02 GO:0042060 wound healing
1.37 1.57e-02 GO:0009890 negative regulation of biosynthetic process
1.40 1.86e-02 GO:0010629 negative regulation of gene expression
1.56 2.13e-02 GO:0007610 behavior
1.53 2.17e-02 GO:0045597 positive regulation of cell differentiation
1.62 2.38e-02 GO:0050767 regulation of neurogenesis
1.36 2.78e-02 GO:0009790 embryo development
1.56 2.85e-02 GO:0048729 tissue morphogenesis
1.44 2.93e-02 GO:0045859 regulation of protein kinase activity
1.38 3.70e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.56 3.79e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.56 3.82e-02 GO:0040012 regulation of locomotion
1.14 3.86e-02 GO:0051179 localization
1.36 3.89e-02 GO:0009719 response to endogenous stimulus
1.28 4.07e-02 GO:0051246 regulation of protein metabolic process
1.49 4.37e-02 GO:0048598 embryonic morphogenesis
1.30 4.37e-02 GO:0070887 cellular response to chemical stimulus
1.62 4.39e-02 GO:0032101 regulation of response to external stimulus
1.38 4.43e-02 GO:0009725 response to hormone stimulus
1.17 4.67e-02 GO:0031326 regulation of cellular biosynthetic process
1.58 4.91e-02 GO:0030334 regulation of cell migration

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 5.87e-06 GO:0044459 plasma membrane part
1.38 6.24e-05 GO:0005626 insoluble fraction
1.38 1.03e-04 GO:0005624 membrane fraction
1.31 2.54e-04 GO:0000267 cell fraction
1.84 8.83e-04 GO:0005912 adherens junction
1.40 1.07e-03 GO:0030054 cell junction
1.36 1.44e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.20 1.85e-03 GO:0005829 cytosol
1.48 2.31e-03 GO:0043005 neuron projection
1.75 2.80e-03 GO:0070161 anchoring junction
1.49 3.17e-03 GO:0009986 cell surface
1.34 3.42e-03 GO:0031988 membrane-bounded vesicle
1.32 7.51e-03 GO:0031410 cytoplasmic vesicle
1.12 9.60e-03 GO:0071944 cell periphery
1.31 1.35e-02 GO:0031982 vesicle
1.07 1.80e-02 GO:0005737 cytoplasm
1.42 2.10e-02 GO:0045202 synapse
1.12 2.18e-02 GO:0005886 plasma membrane
1.50 2.26e-02 GO:0015629 actin cytoskeleton
2.24 2.88e-02 GO:0005901 caveola
2.49 3.55e-02 GO:0005581 collagen
1.46 4.21e-02 GO:0044433 cytoplasmic vesicle part
1.42 4.42e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 1.71e-18 GO:0005515 protein binding
1.59 3.47e-10 GO:0043565 sequence-specific DNA binding
1.47 2.21e-09 GO:0001071 nucleic acid binding transcription factor activity
1.47 2.21e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.07 3.41e-08 GO:0005488 binding
1.39 2.11e-06 GO:0030528 transcription regulator activity
1.41 6.61e-05 GO:0042802 identical protein binding
1.58 6.28e-04 GO:0003779 actin binding
1.46 3.52e-03 GO:0042803 protein homodimerization activity
1.46 3.96e-03 GO:0019904 protein domain specific binding
1.53 5.53e-03 GO:0016563 transcription activator activity
1.40 7.07e-03 GO:0008092 cytoskeletal protein binding
1.58 1.09e-02 GO:0005096 GTPase activator activity
1.33 1.23e-02 GO:0019899 enzyme binding
1.46 1.32e-02 GO:0008047 enzyme activator activity
1.35 1.40e-02 GO:0046983 protein dimerization activity
1.75 2.23e-02 GO:0022843 voltage-gated cation channel activity
4.42 2.24e-02 GO:0005283 sodium:amino acid symporter activity
2.38 2.59e-02 GO:0001948 glycoprotein binding
1.28 2.70e-02 GO:0030234 enzyme regulator activity
1.40 3.03e-02 GO:0030695 GTPase regulator activity