Motif ID: SMAD1..7,9.p2

Z-value: 2.105


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMAD9chr13_-_37494370-0.742.9e-06Click!
SMAD3chr15_+_673581940.675.4e-05Click!
SMAD4chr18_+_48556483-0.667.7e-05Click!
SMAD1chr4_+_146403955-0.622.9e-04Click!
SMAD2chr18_-_45457454-0.551.7e-03Click!
SMAD6chr15_+_67000929-0.384.1e-02Click!
SMAD7chr18_-_464757020.291.2e-01Click!
SMAD5chr5_+_1354685380.077.3e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_48328601 15.040 NM_033518
SLC38A5
solute carrier family 38, member 5
chrX_-_48328564 9.589 SLC38A5
solute carrier family 38, member 5
chr5_-_151066445 9.460 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_-_50349811 8.748 NM_153281
HYAL1
hyaluronoglucosaminidase 1
chr19_-_51472816 7.422 NM_002774
KLK6
kallikrein-related peptidase 6
chr12_-_47473424 6.925 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr5_-_151066492 6.682 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr19_-_36019194 6.592 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr17_+_70117154 6.271 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr11_-_125366048 6.157 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr22_+_38035683 6.116 NM_018957
SH3BP1
SH3-domain binding protein 1
chr7_+_134464417 5.691 CALD1
caldesmon 1
chr19_-_11689591 5.409 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr1_-_6445737 5.339 NM_181864
ACOT7
acyl-CoA thioesterase 7
chrX_-_106959597 4.987 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr15_-_90039776 4.877 NM_016321
RHCG
Rh family, C glycoprotein
chr9_+_35673852 4.818 NM_001216
CA9
carbonic anhydrase IX
chr9_-_123639566 4.776 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr9_-_139890984 4.739 NM_004669
CLIC3
chloride intracellular channel 3
chr19_-_44285012 4.704 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr8_-_6735438 4.669 NM_005218
DEFB1
defensin, beta 1
chr8_-_143867931 4.660 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr17_-_5138049 4.542 NM_207103
SCIMP
SLP adaptor and CSK interacting membrane protein
chr19_-_44285407 4.540 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr4_-_111119752 4.418 NM_001130721
NM_024090
ELOVL6

ELOVL fatty acid elongase 6

chr19_-_11689765 4.315 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr8_+_32504250 4.276 NM_013959
NRG1
neuregulin 1
chr7_+_134464161 4.238 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr2_+_95691428 4.169 NM_002371
NM_022438
NM_022439
NM_022440
MAL



mal, T-cell differentiation protein



chr19_-_41934634 4.071 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr15_-_83953465 4.028 NM_001717
BNC1
basonuclin 1
chrX_-_132095422 3.991 NM_001077188
NM_147175
HS6ST2

heparan sulfate 6-O-sulfotransferase 2

chr22_+_31477231 3.868 NM_006932
NM_134269
NM_134270
SMTN


smoothelin


chr1_-_24469571 3.843 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr12_+_53443834 3.798 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chrX_-_106960028 3.770 TSC22D3
TSC22 domain family, member 3
chr1_+_65991357 3.760 NM_001198687
NM_001198688
NM_001198689
LEPR


leptin receptor


chr1_+_183155173 3.738 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr19_-_41933255 3.710


chr11_+_66824308 3.674 RHOD
ras homolog gene family, member D
chr19_+_48828627 3.666 NM_001425
EMP3
epithelial membrane protein 3
chr22_+_31489343 3.662 SMTN
smoothelin
chr19_+_48828820 3.651 EMP3
epithelial membrane protein 3
chr9_+_140119643 3.587 NM_199001
C9orf169
chromosome 9 open reading frame 169
chr1_-_26680620 3.583 NM_001039775
AIM1L
absent in melanoma 1-like
chr19_-_51472003 3.525 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr9_-_123639462 3.405 PHF19
PHD finger protein 19
chr2_-_110874142 3.326 NM_005434
MALL
mal, T-cell differentiation protein-like
chr1_-_109825683 3.325 PSRC1
proline/serine-rich coiled-coil 1
chr1_-_120190389 3.316 NM_001080470
ZNF697
zinc finger protein 697
chr19_-_35992798 3.286 NM_001035516
DMKN
dermokine
chr12_-_76425207 3.226 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr1_+_183155393 3.190 LAMC2
laminin, gamma 2
chr7_+_134464372 3.142 CALD1
caldesmon 1
chr1_-_149908098 3.106 NM_181873
MTMR11
myotubularin related protein 11
chr1_+_183155361 3.089 LAMC2
laminin, gamma 2
chr14_-_94423766 3.052 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chr7_-_41742666 3.049 NM_002192
INHBA
inhibin, beta A
chr19_-_51456159 3.013 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr22_+_40390935 3.002 NM_138435
FAM83F
family with sequence similarity 83, member F
chr20_+_30598244 2.993 NM_080625
C20orf160
chromosome 20 open reading frame 160
chr12_+_47473367 2.988 FAM113B
family with sequence similarity 113, member B
chr11_+_117075682 2.981 TAGLN
transgelin
chr18_+_21269528 2.945 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr8_-_8239188 2.871 NM_001080826
SGK223
homolog of rat pragma of Rnd2
chr1_-_109825767 2.843 NM_001005290
NM_001032291
NM_032636
PSRC1


proline/serine-rich coiled-coil 1


chr12_+_53491417 2.825 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr1_+_65991390 2.792 LEPR
leptin receptor
chrX_+_153029578 2.782 NM_001163257
NM_005393
PLXNB3

plexin B3

chr17_-_1395950 2.743 NM_001080779
MYO1C
myosin IC
chr3_+_136537860 2.718 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr12_+_107712151 2.714 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr3_+_50316517 2.660 NM_153215
C3orf45
chromosome 3 open reading frame 45
chr4_-_139163222 2.624 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_+_37571752 2.601 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr12_+_53491448 2.592 IGFBP6
insulin-like growth factor binding protein 6
chr19_+_45281125 2.564 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chr5_+_31193761 2.558 NM_004932
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr15_-_74495093 2.518 NM_001199042
NM_022369
STRA6

stimulated by retinoic acid gene 6 homolog (mouse)

chr7_-_1199822 2.506 NM_182491
ZFAND2A
zinc finger, AN1-type domain 2A
chr15_-_74494780 2.490 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr17_-_74581934 2.477 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr20_+_44441671 2.462 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr17_+_26662547 2.461 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr2_-_102003923 2.448 NM_153836
CREG2
cellular repressor of E1A-stimulated genes 2
chr5_-_136834887 2.433 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr13_-_20806533 2.406 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr21_+_39628869 2.371 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_43919345 2.353 HYI
hydroxypyruvate isomerase (putative)
chr19_-_7040183 2.333 NM_001164419
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr20_-_32899607 2.313 NM_001161766
AHCY
adenosylhomocysteinase
chr2_+_219472487 2.312 NM_032726
PLCD4
phospholipase C, delta 4
chr2_-_110873638 2.308 MALL
mal, T-cell differentiation protein-like
chr11_-_66103874 2.273 NM_004292
RIN1
Ras and Rab interactor 1
chr5_+_87564729 2.266 LOC100505894
uncharacterized LOC100505894
chr15_-_74494851 2.264 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr22_+_33197678 2.262 TIMP3
TIMP metallopeptidase inhibitor 3
chr12_-_122231554 2.256 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr7_-_1199785 2.252 ZFAND2A
zinc finger, AN1-type domain 2A
chr1_-_155177685 2.247 NM_001252607
NM_001252608
NM_007112
THBS3


thrombospondin 3


chr15_-_74502045 2.239 NM_001199040
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr7_+_76139744 2.227 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr2_+_30454396 2.226 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr17_-_80044975 2.226 FASN
fatty acid synthase
chr8_-_144654921 2.217 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chrX_-_8700132 2.203 KAL1
Kallmann syndrome 1 sequence
chr3_+_50304989 2.198 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chrX_-_13062720 2.178 NM_174901
FAM9C
family with sequence similarity 9, member C
chr11_+_43963809 2.172 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr22_+_22988781 2.165 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr1_-_43919547 2.161 NM_001190880
NM_001243526
NM_031207
HYI


hydroxypyruvate isomerase (putative)


chr15_-_73661141 2.160 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr7_-_1199813 2.155 ZFAND2A
zinc finger, AN1-type domain 2A
chr16_+_88705000 2.153 NM_013278
IL17C
interleukin 17C
chr19_+_10381516 2.144 NM_000201
ICAM1
intercellular adhesion molecule 1
chr11_-_568419 2.136 MIR210HG
MIR210 host gene (non-protein coding)
chr19_+_2249112 2.124 NM_000479
AMH
anti-Mullerian hormone
chr17_-_39092714 2.122 KRT23
keratin 23 (histone deacetylase inducible)
chrX_-_106960268 2.113 NM_004089
TSC22D3
TSC22 domain family, member 3
chr2_+_219472631 2.106 PLCD4
phospholipase C, delta 4
chr2_+_219472618 2.104 PLCD4
phospholipase C, delta 4
chr20_-_23967431 2.095 NM_178312
GGTLC1
gamma-glutamyltransferase light chain 1
chr16_+_8806825 2.079 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr19_+_7049349 2.065 NM_144614
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr1_+_109792640 2.052 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr10_+_11784355 2.051 NM_024693
ECHDC3
enoyl CoA hydratase domain containing 3
chr3_+_52350334 2.050 NM_015512
DNAH1
dynein, axonemal, heavy chain 1
chr11_+_35160666 2.030 CD44
CD44 molecule (Indian blood group)
chr20_+_361675 2.028 TRIB3
tribbles homolog 3 (Drosophila)
chr12_-_54778456 2.012 NM_015481
ZNF385A
zinc finger protein 385A
chr13_+_43136871 2.011 NM_033012
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr1_+_37940074 2.010 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr11_-_61062534 2.002 VWCE
von Willebrand factor C and EGF domains
chr7_-_102283237 1.995 NM_001114403
UPK3BL
uroplakin 3B-like
chr4_+_2813966 1.986 SH3BP2
SH3-domain binding protein 2
chr2_-_85637473 1.971 CAPG
capping protein (actin filament), gelsolin-like
chr7_+_134233848 1.971 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr1_+_16091458 1.969 NM_001024216
FBLIM1
filamin binding LIM protein 1
chr21_+_39628663 1.959 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_+_135614310 1.952 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr20_+_34700257 1.952 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_-_139652685 1.894 NM_178469
LCN8
lipocalin 8
chr4_-_175443601 1.886 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr4_-_175443791 1.886 NM_000860
NM_001145816
HPGD

hydroxyprostaglandin dehydrogenase 15-(NAD)

chr17_-_39968145 1.880 LEPREL4
leprecan-like 4
chr9_+_126118447 1.878 NM_173689
CRB2
crumbs homolog 2 (Drosophila)
chr1_+_37940129 1.870 ZC3H12A
zinc finger CCCH-type containing 12A
chr7_+_1580009 1.868 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr15_-_72598655 1.864 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr17_-_80054216 1.857 FASN
fatty acid synthase
chr15_+_33603162 1.852 NM_001036
NM_001243996
RYR3

ryanodine receptor 3

chr7_-_99766238 1.846 NM_024637
GAL3ST4
galactose-3-O-sulfotransferase 4
chr1_+_37940180 1.846 ZC3H12A
zinc finger CCCH-type containing 12A
chr15_-_30114336 1.844 TJP1
tight junction protein 1 (zona occludens 1)
chr4_+_156680603 1.843 GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr7_+_74188308 1.836 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chrX_+_44703248 1.832 NM_022076
DUSP21
dual specificity phosphatase 21
chr17_-_7297826 1.818 PLSCR3
phospholipid scramblase 3
chr15_+_81071708 1.816 NM_018689
KIAA1199
KIAA1199
chr10_-_5541401 1.815 NM_017422
CALML5
calmodulin-like 5
chr11_+_126275947 1.806 ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr10_+_88718287 1.784 NM_003087
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr20_+_361938 1.783 TRIB3
tribbles homolog 3 (Drosophila)
chr14_+_37126772 1.783 NM_006194
PAX9
paired box 9
chr7_-_1595746 1.777 NM_001097620
TMEM184A
transmembrane protein 184A
chr2_+_17721806 1.768 NM_003385
VSNL1
visinin-like 1
chr16_+_46919101 1.753 NM_001142466
GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr1_+_156863522 1.735 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr9_-_35111534 1.729 FAM214B
family with sequence similarity 214, member B
chr3_-_52569021 1.722 NM_022908
NT5DC2
5'-nucleotidase domain containing 2
chr8_+_22409423 1.717 SORBS3
sorbin and SH3 domain containing 3
chr19_-_43709692 1.717 NM_002780
NM_213633
PSG4

pregnancy specific beta-1-glycoprotein 4

chr16_-_79634610 1.715 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr2_+_158114109 1.707 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr6_+_106534188 1.703 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr11_+_66824285 1.700 NM_014578
RHOD
ras homolog gene family, member D
chrX_+_152086408 1.700 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr8_+_128748476 1.694 MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
chr16_-_10912456 1.688 NM_001079512
FAM18A
family with sequence similarity 18, member A
chr7_-_100860615 1.684 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr3_+_9944295 1.683 NM_153483
IL17RE
interleukin 17 receptor E
chr4_+_37828270 1.682 NM_018290
PGM2
phosphoglucomutase 2
chr8_+_128748312 1.681 NM_002467
MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
chrX_-_107019001 1.679 NM_198057
TSC22D3
TSC22 domain family, member 3
chrX_-_107018889 1.675 TSC22D3
TSC22 domain family, member 3
chrX_-_153602928 1.672 FLNA
filamin A, alpha
chr2_+_17721983 1.669 VSNL1
visinin-like 1
chr12_+_53440809 1.660 NM_198316
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_11196213 1.655 NM_001098212
HRH1
histamine receptor H1
chr13_+_111138079 1.641 COL4A2
collagen, type IV, alpha 2
chr7_-_44228880 1.636 NM_000162
GCK
glucokinase (hexokinase 4)
chr17_-_74582144 1.635 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr12_+_13043955 1.631 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr6_-_30655671 1.627 NM_133471
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr2_+_113885137 1.615 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr2_+_233404436 1.614 NM_005199
CHRNG
cholinergic receptor, nicotinic, gamma
chr19_-_2038937 1.613 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr3_-_195619451 1.612 TNK2
tyrosine kinase, non-receptor, 2
chrX_+_100663205 1.609 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr11_+_117857123 1.579 IL10RA
interleukin 10 receptor, alpha

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 1.24e-11 GO:0023052 signaling
1.12 3.04e-11 GO:0009987 cellular process
1.18 3.25e-11 GO:0065007 biological regulation
1.32 6.98e-10 GO:0007165 signal transduction
1.18 7.74e-10 GO:0050789 regulation of biological process
1.51 3.45e-08 GO:0051239 regulation of multicellular organismal process
1.18 3.87e-08 GO:0050794 regulation of cellular process
1.24 3.76e-07 GO:0051716 cellular response to stimulus
1.31 4.43e-07 GO:0048731 system development
1.34 2.69e-06 GO:0065008 regulation of biological quality
1.26 2.83e-06 GO:0007275 multicellular organismal development
1.32 4.93e-06 GO:0048519 negative regulation of biological process
1.24 5.29e-06 GO:0032502 developmental process
1.27 5.88e-06 GO:0048856 anatomical structure development
1.17 7.09e-06 GO:0050896 response to stimulus
1.55 1.11e-05 GO:0040011 locomotion
1.33 2.72e-05 GO:0030154 cell differentiation
1.49 2.87e-05 GO:0007154 cell communication
1.35 3.01e-05 GO:0048513 organ development
1.32 4.84e-05 GO:0048523 negative regulation of cellular process
3.55 7.44e-05 GO:0007422 peripheral nervous system development
1.51 7.49e-05 GO:0009611 response to wounding
1.50 8.25e-05 GO:0050793 regulation of developmental process
1.32 8.53e-05 GO:0048869 cellular developmental process
1.76 1.25e-04 GO:0016477 cell migration
1.37 1.91e-04 GO:0009653 anatomical structure morphogenesis
1.66 2.04e-04 GO:0008284 positive regulation of cell proliferation
1.47 2.18e-04 GO:0009605 response to external stimulus
1.66 2.19e-04 GO:0006935 chemotaxis
1.66 2.19e-04 GO:0042330 taxis
1.26 3.39e-04 GO:0048518 positive regulation of biological process
1.62 4.75e-04 GO:0006928 cellular component movement
1.46 4.98e-04 GO:0042127 regulation of cell proliferation
1.45 6.31e-04 GO:0032879 regulation of localization
1.46 6.96e-04 GO:0048468 cell development
1.42 9.18e-04 GO:0051246 regulation of protein metabolic process
1.28 1.03e-03 GO:0042221 response to chemical stimulus
5.32 1.08e-03 GO:0030513 positive regulation of BMP signaling pathway
5.32 1.08e-03 GO:0048484 enteric nervous system development
1.91 1.32e-03 GO:0051241 negative regulation of multicellular organismal process
1.37 1.40e-03 GO:0035556 intracellular signal transduction
1.47 1.46e-03 GO:0009888 tissue development
1.16 1.68e-03 GO:0032501 multicellular organismal process
1.65 1.78e-03 GO:0048870 cell motility
1.65 1.78e-03 GO:0051674 localization of cell
1.49 2.13e-03 GO:0007267 cell-cell signaling
2.22 2.36e-03 GO:0048589 developmental growth
1.32 2.38e-03 GO:0023051 regulation of signaling
1.56 2.45e-03 GO:0042060 wound healing
1.75 2.55e-03 GO:0051240 positive regulation of multicellular organismal process
1.90 2.64e-03 GO:0040007 growth
1.49 2.98e-03 GO:2000026 regulation of multicellular organismal development
6.45 4.07e-03 GO:0048880 sensory system development
6.45 4.07e-03 GO:0048892 lateral line nerve development
6.45 4.07e-03 GO:0048895 lateral line nerve glial cell differentiation
6.45 4.07e-03 GO:0048925 lateral line system development
6.45 4.07e-03 GO:0048937 lateral line nerve glial cell development
6.45 4.07e-03 GO:0050935 iridophore differentiation
3.43 5.73e-03 GO:0021675 nerve development
1.40 6.97e-03 GO:0032268 regulation of cellular protein metabolic process
1.24 7.17e-03 GO:0048522 positive regulation of cellular process
3.03 8.11e-03 GO:0060560 developmental growth involved in morphogenesis
5.45 1.05e-02 GO:0048846 axon extension involved in axon guidance
1.42 1.10e-02 GO:0022008 neurogenesis
1.47 1.13e-02 GO:0051049 regulation of transport
3.76 1.20e-02 GO:0048483 autonomic nervous system development
3.42 1.24e-02 GO:0014032 neural crest cell development
1.70 1.32e-02 GO:0007411 axon guidance
3.25 1.46e-02 GO:0014033 neural crest cell differentiation
1.94 1.49e-02 GO:0006874 cellular calcium ion homeostasis
1.66 1.62e-02 GO:0090066 regulation of anatomical structure size
1.69 1.69e-02 GO:0044057 regulation of system process
1.91 1.71e-02 GO:0055074 calcium ion homeostasis
1.91 1.71e-02 GO:0072503 cellular divalent inorganic cation homeostasis
1.27 1.74e-02 GO:0048583 regulation of response to stimulus
1.52 1.94e-02 GO:0050878 regulation of body fluid levels
1.56 1.96e-02 GO:0007599 hemostasis
1.42 1.97e-02 GO:0048699 generation of neurons
2.26 2.03e-02 GO:0061138 morphogenesis of a branching epithelium
2.14 2.03e-02 GO:0001763 morphogenesis of a branching structure
1.37 2.29e-02 GO:0010646 regulation of cell communication
1.88 2.30e-02 GO:0072507 divalent inorganic cation homeostasis
1.19 2.32e-02 GO:0080090 regulation of primary metabolic process
1.47 2.35e-02 GO:0045595 regulation of cell differentiation
6.35 2.62e-02 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
1.58 3.12e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.19 3.18e-02 GO:0016043 cellular component organization
1.18 3.37e-02 GO:0051179 localization
1.57 3.54e-02 GO:0048812 neuron projection morphogenesis
1.54 3.79e-02 GO:0000904 cell morphogenesis involved in differentiation
1.30 4.05e-02 GO:0007399 nervous system development
1.54 4.10e-02 GO:0019226 transmission of nerve impulse
1.54 4.10e-02 GO:0031175 neuron projection development
1.54 4.10e-02 GO:0035637 multicellular organismal signaling
1.50 4.31e-02 GO:0048666 neuron development
1.58 4.33e-02 GO:0007409 axonogenesis
1.27 4.35e-02 GO:0007166 cell surface receptor linked signaling pathway
1.54 4.50e-02 GO:0007596 blood coagulation
1.54 4.50e-02 GO:0050817 coagulation
1.45 4.85e-02 GO:0030182 neuron differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.11 1.30e-04 GO:0070161 anchoring junction
2.14 2.56e-04 GO:0005912 adherens junction
1.78 4.79e-04 GO:0015629 actin cytoskeleton
1.25 1.08e-03 GO:0044459 plasma membrane part
1.50 2.21e-03 GO:0030054 cell junction
2.27 3.22e-03 GO:0005925 focal adhesion
1.16 5.55e-03 GO:0071944 cell periphery
2.15 8.24e-03 GO:0030055 cell-substrate junction
1.39 8.40e-03 GO:0005626 insoluble fraction
2.16 9.75e-03 GO:0005924 cell-substrate adherens junction
1.15 1.65e-02 GO:0005886 plasma membrane
1.23 2.00e-02 GO:0005829 cytosol
1.31 3.10e-02 GO:0000267 cell fraction
1.79 4.29e-02 GO:0031252 cell leading edge

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 7.21e-09 GO:0005515 protein binding
1.64 3.89e-05 GO:0008092 cytoskeletal protein binding
1.78 2.23e-04 GO:0003779 actin binding