Motif ID: SNAI1..3.p2

Z-value: 1.573


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SNAI2chr8_-_49833823-0.641.2e-04Click!
SNAI1chr20_+_48599511-0.241.9e-01Click!
SNAI3chr16_-_88752788-0.202.8e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_149363498 9.949 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr4_-_16085593 8.261 NM_001145847
NM_001145848
PROM1

prominin 1

chr4_-_16085309 8.248 PROM1
prominin 1
chr1_-_109656478 7.307 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr11_+_73358593 7.306 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr3_+_63638343 7.198 NM_001080537
SNTN
sentan, cilia apical structure protein
chr4_+_55523906 6.079 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr7_-_73184535 6.024 NM_001306
CLDN3
claudin 3
chr5_+_156693051 5.525 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr15_+_50474357 5.511 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr1_+_60280462 4.949 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr9_-_97401588 4.947 FBP1
fructose-1,6-bisphosphatase 1
chr16_-_52581713 4.812 NM_001146188
TOX3
TOX high mobility group box family member 3
chr16_+_67465019 4.748 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr3_-_121740968 4.639 NM_001199799
NM_001199800
NM_175924
ILDR1


immunoglobulin-like domain containing receptor 1


chr20_+_31823801 4.636 NM_001243193
NM_016583
NM_130852
BPIFA1


BPI fold containing family A, member 1


chr19_-_3028901 4.572 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr1_-_207119707 4.550 NM_002644
PIGR
polymeric immunoglobulin receptor
chr1_-_27339326 4.381 NM_052943
FAM46B
family with sequence similarity 46, member B
chr13_+_35516390 4.363 NM_015678
NBEA
neurobeachin
chr16_-_54318889 4.267 IRX3
iroquois homeobox 3
chr9_-_97401746 4.205 FBP1
fructose-1,6-bisphosphatase 1
chr4_-_16085666 4.028 PROM1
prominin 1
chr1_-_40782981 3.967 COL9A2
collagen, type IX, alpha 2
chr7_-_16921596 3.921 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr19_-_14316980 3.913 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr9_-_97401833 3.800 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr16_+_811049 3.644 NM_013404
MSLN
mesothelin
chr1_-_57285368 3.631 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr20_+_44098392 3.608 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr10_-_13043570 3.594 NM_031455
CCDC3
coiled-coil domain containing 3
chr1_+_151483861 3.457 NM_020770
CGN
cingulin
chr1_-_40782924 3.403 NM_001852
COL9A2
collagen, type IX, alpha 2
chr6_+_16129321 3.390 MYLIP
myosin regulatory light chain interacting protein
chr1_-_75139421 3.385 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr9_-_75567915 3.291 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr9_-_75568232 3.214 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr7_-_131241321 3.104 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr18_-_24765178 3.102 NM_031422
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr2_+_10861740 3.090 NM_001039362
NM_144583
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr17_+_73521744 3.024 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr11_+_111789600 2.972 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr8_-_110657025 2.940 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr9_+_17578952 2.897 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr11_+_111789658 2.885 C11orf52
chromosome 11 open reading frame 52
chr18_-_45663667 2.852 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr19_-_7990974 2.794 NM_206833
CTXN1
cortexin 1
chr1_-_40367539 2.786 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr2_+_121103670 2.782 NM_002193
INHBB
inhibin, beta B
chr2_+_223289212 2.750 SGPP2
sphingosine-1-phosphate phosphatase 2
chr2_+_223289285 2.742 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr14_-_61748193 2.715


chr14_-_106926393 2.708 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_29603499 2.681 PRR15
proline rich 15
chr11_+_27062508 2.679 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr14_-_100625931 2.659 NM_206918
DEGS2
delta(4)-desaturase, sphingolipid 2
chr2_+_71162995 2.652 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr19_+_17982753 2.575 NM_000453
SLC5A5
solute carrier family 5 (sodium iodide symporter), member 5
chr19_+_14544216 2.571 PKN1
protein kinase N1
chr1_+_46646199 2.559 TSPAN1
tetraspanin 1
chr7_+_106685007 2.526 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr20_-_3149070 2.526 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr1_-_22469414 2.510 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr5_-_101631965 2.490 NM_180991
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr1_+_118148506 2.480 NM_017709
FAM46C
family with sequence similarity 46, member C
chr9_+_976963 2.478 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr1_-_117746457 2.459 NM_001253849
VTCN1
V-set domain containing T cell activation inhibitor 1
chr1_-_27339448 2.436 FAM46B
family with sequence similarity 46, member B
chr8_-_17270800 2.419 MTMR7
myotubularin related protein 7
chr17_-_72968750 2.414


chr1_+_246887377 2.406 NM_016002
SCCPDH
saccharopine dehydrogenase (putative)
chr1_-_23885916 2.380 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr17_-_46035109 2.366 NM_024320
PRR15L
proline rich 15-like
chr8_+_99076749 2.296 NM_001170806
NM_173549
C8orf47

chromosome 8 open reading frame 47

chr1_+_118148668 2.269 FAM46C
family with sequence similarity 46, member C
chr22_-_50971007 2.268 NM_001014440
ODF3B
outer dense fiber of sperm tails 3B
chrX_+_13587693 2.258 NM_001167890
NM_015507
EGFL6

EGF-like-domain, multiple 6

chr11_-_2019070 2.256 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr2_+_205410465 2.249 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr15_+_74218962 2.232 LOXL1
lysyl oxidase-like 1
chr9_+_74764266 2.230 NM_001242505
NM_001242506
NM_004293
GDA


guanine deaminase


chr16_-_74808474 2.192 FA2H
fatty acid 2-hydroxylase
chr2_-_230579198 2.168 NM_139072
DNER
delta/notch-like EGF repeat containing
chr7_+_12610202 2.163 NM_001112706
SCIN
scinderin
chr1_+_104159953 2.159 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr4_-_147866963 2.134 NM_031956
TTC29
tetratricopeptide repeat domain 29
chr2_-_27712520 2.124 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr11_-_2018568 2.119 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr11_+_827584 2.112 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr6_-_90121966 2.111 NM_021244
RRAGD
Ras-related GTP binding D
chr10_+_94608224 2.081 NM_019053
EXOC6
exocyst complex component 6
chr6_-_90121656 2.066 RRAGD
Ras-related GTP binding D
chr17_-_4463816 2.039 NM_001122890
NM_153338
GGT6

gamma-glutamyltransferase 6

chr1_+_18807423 2.008 NM_152375
KLHDC7A
kelch domain containing 7A
chr1_-_85930610 1.998 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_-_51810693 1.989 NM_001144832
TTC39A
tetratricopeptide repeat domain 39A
chr15_+_75287829 1.986 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr11_-_2018703 1.981 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr16_-_74808699 1.979 NM_024306
FA2H
fatty acid 2-hydroxylase
chr22_+_31003069 1.943 NM_000355
NM_001184726
TCN2

transcobalamin II

chr17_-_72968790 1.941 NM_030630
C17orf28
chromosome 17 open reading frame 28
chr6_-_90121911 1.924 RRAGD
Ras-related GTP binding D
chr16_-_75529289 1.923


chr6_+_31783314 1.921 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr11_-_2018446 1.903 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr7_+_150065330 1.901 REPIN1
replication initiator 1
chrX_-_8700170 1.884 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr19_+_54042041 1.865 NM_001253800
ZNF331
zinc finger protein 331
chr20_+_56725982 1.850 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr7_-_124405029 1.850 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_-_40782826 1.828 COL9A2
collagen, type IX, alpha 2
chr9_+_74764382 1.828 GDA
guanine deaminase
chr5_-_134914968 1.827 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr10_+_71211215 1.818 NM_012339
TSPAN15
tetraspanin 15
chr4_-_25864430 1.815 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr9_+_74764394 1.814 GDA
guanine deaminase
chr17_-_40346427 1.800 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr12_+_56473944 1.795 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr6_+_31783530 1.786 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr11_-_2019007 1.770 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr9_+_977386 1.767 DMRT3
doublesex and mab-3 related transcription factor 3
chr5_+_131630065 1.762 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr11_-_9225780 1.756 DENND5A
DENN/MADD domain containing 5A
chr10_+_43867089 1.748 NM_001184963
NM_173160
FXYD4

FXYD domain containing ion transport regulator 4

chr9_-_126030792 1.740 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr19_+_5914192 1.736 NM_004058
NM_080590
CAPS

calcyphosine

chr13_+_24734788 1.732 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr22_-_36013303 1.724 NM_005368
NM_203378
MB

myoglobin

chr2_+_149894980 1.716 NM_177964
LYPD6B
LY6/PLAUR domain containing 6B
chr16_+_57392694 1.707 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr9_-_86432546 1.702 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr1_-_183622447 1.702 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr2_+_97481977 1.696 NM_017623
NM_199078
CNNM3

cyclin M3

chr7_-_122526781 1.695 NM_001009571
NM_001167940
NM_017954
CADPS2


Ca++-dependent secretion activator 2


chr11_+_86511490 1.677 NM_007173
PRSS23
protease, serine, 23
chr22_-_50970542 1.675 ODF3B
outer dense fiber of sperm tails 3B
chr5_-_149792370 1.674 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr5_-_149792276 1.668 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr20_-_55841090 1.667 BMP7
bone morphogenetic protein 7
chr11_-_2018334 1.666 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr16_-_23724820 1.665 NM_033266
ERN2
endoplasmic reticulum to nucleus signaling 2
chr2_-_154335181 1.656 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr3_-_120400957 1.643 HGD
homogentisate 1,2-dioxygenase
chr10_+_22634373 1.641 NM_001253854
NM_001253855
NM_012443
NM_172242
SPAG6



sperm associated antigen 6



chr19_-_9092017 1.640 NM_024690
MUC16
mucin 16, cell surface associated
chr8_-_17271015 1.625 NM_004686
MTMR7
myotubularin related protein 7
chr8_+_145722108 1.623 NM_032902
PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr1_+_154975201 1.622 NM_001252406
ZBTB7B
zinc finger and BTB domain containing 7B
chr5_-_134914447 1.621 CXCL14
chemokine (C-X-C motif) ligand 14
chr1_+_159750756 1.621 NM_017823
DUSP23
dual specificity phosphatase 23
chr7_+_29603388 1.618 NM_175887
PRR15
proline rich 15
chr4_-_54457723 1.612 NM_001126328
LNX1
ligand of numb-protein X 1
chr3_-_120401401 1.611 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr4_-_75719686 1.607 NM_001729
BTC
betacellulin
chr11_-_108464344 1.601 NM_015065
EXPH5
exophilin 5
chr11_+_61976139 1.601 NM_002407
SCGB2A1
secretoglobin, family 2A, member 1
chr12_+_56473808 1.595 NM_001982
NM_001005915
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr9_-_80263222 1.588 NM_004297
GNA14
guanine nucleotide binding protein (G protein), alpha 14
chr12_-_25348031 1.578 NM_001082972
NM_001082973
NM_001204101
NM_001204102
NM_018272
CASC1




cancer susceptibility candidate 1




chr22_+_29313376 1.572 NM_032173
ZNRF3
zinc and ring finger 3
chr12_+_51318743 1.562 METTL7A
methyltransferase like 7A
chr3_+_32148136 1.561 GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr13_-_52585472 1.555 NM_000053
NM_001005918
NM_001243182
ATP7B


ATPase, Cu++ transporting, beta polypeptide


chr10_+_92980507 1.552 PCGF5
polycomb group ring finger 5
chr5_+_140186658 1.552 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr5_+_140213968 1.549 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr9_-_126030854 1.548 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr15_-_52587851 1.548 NM_018728
MYO5C
myosin VC
chr4_-_54457628 1.538 LNX1
ligand of numb-protein X 1
chr11_+_2466171 1.535 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr20_-_20693122 1.513 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr11_-_62472901 1.512


chr19_-_18717631 1.510 NM_004750
CRLF1
cytokine receptor-like factor 1
chr5_+_140261792 1.509 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr5_+_169532900 1.508 NM_012188
NM_144769
FOXI1

forkhead box I1

chr11_+_120110902 1.508 NM_014352
POU2F3
POU class 2 homeobox 3
chr10_+_92980322 1.506 NM_032373
PCGF5
polycomb group ring finger 5
chr11_+_7618416 1.500 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_-_33890931 1.497 LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_34533117 1.493 NM_001243081
NM_198381
ELF5

E74-like factor 5 (ets domain transcription factor)

chr7_+_17338182 1.488 NM_001621
AHR
aryl hydrocarbon receptor
chr2_-_178257380 1.487 LOC100130691
uncharacterized LOC100130691
chr19_-_40440532 1.479 NM_003890
FCGBP
Fc fragment of IgG binding protein
chr11_-_33913835 1.478 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_+_3614609 1.465 NM_001204192
TP73
tumor protein p73
chr2_-_28113211 1.464 NM_022128
RBKS
ribokinase
chr17_-_8702438 1.457 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr19_-_18717577 1.457 CRLF1
cytokine receptor-like factor 1
chr3_-_50383009 1.451 NM_015896
ZMYND10
zinc finger, MYND-type containing 10
chr2_+_191273012 1.445 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr3_+_49449753 1.437 TCTA
T-cell leukemia translocation altered gene
chr21_+_34922923 1.436 SON
SON DNA binding protein
chr5_+_76114832 1.417 NM_005242
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr9_-_117160748 1.410 AKNA
AT-hook transcription factor
chr1_+_154975041 1.409 NM_001252405
NM_015872
ZBTB7B

zinc finger and BTB domain containing 7B

chr5_-_150603615 1.408 CCDC69
coiled-coil domain containing 69
chr9_+_135753711 1.406 C9orf9
chromosome 9 open reading frame 9
chr19_-_18717467 1.400 CRLF1
cytokine receptor-like factor 1
chr5_+_76114881 1.383 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr6_-_31845446 1.374 NM_001178045
SLC44A4
solute carrier family 44, member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 1.54e-03 GO:0008104 protein localization
1.24 3.63e-03 GO:0033036 macromolecule localization
1.29 5.85e-03 GO:0045184 establishment of protein localization
1.28 1.21e-02 GO:0015031 protein transport
2.06 2.73e-02 GO:0006818 hydrogen transport
1.07 4.75e-02 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 2.21e-10 GO:0044424 intracellular part
1.07 2.73e-10 GO:0005622 intracellular
1.09 2.88e-09 GO:0043231 intracellular membrane-bounded organelle
1.09 3.13e-09 GO:0043227 membrane-bounded organelle
1.10 1.04e-08 GO:0005737 cytoplasm
1.08 4.36e-07 GO:0043226 organelle
1.07 8.18e-07 GO:0043229 intracellular organelle
1.21 5.56e-06 GO:0031090 organelle membrane
1.10 3.06e-05 GO:0044444 cytoplasmic part
1.22 1.20e-03 GO:0005739 mitochondrion
1.26 1.52e-03 GO:0005794 Golgi apparatus
3.00 4.23e-03 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain
1.36 4.44e-03 GO:0000139 Golgi membrane
1.32 4.62e-03 GO:0044431 Golgi apparatus part
2.24 5.38e-03 GO:0016469 proton-transporting two-sector ATPase complex
1.28 9.31e-03 GO:0031967 organelle envelope
1.28 1.13e-02 GO:0031975 envelope
1.41 2.19e-02 GO:0005743 mitochondrial inner membrane
1.33 2.44e-02 GO:0005740 mitochondrial envelope
1.02 3.27e-02 GO:0044464 cell part
1.02 3.45e-02 GO:0005623 cell
1.38 4.23e-02 GO:0019866 organelle inner membrane
1.36 4.62e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.04 7.43e-03 GO:0005488 binding
1.07 1.78e-02 GO:0005515 protein binding