Motif ID: SOX2.p2

Z-value: 1.557


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_181430075-0.824.1e-08Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153029987 12.999 NM_005988
SPRR2A
small proline-rich protein 2A
chr1_-_153044083 9.089 NM_001017418
SPRR2B
small proline-rich protein 2B
chr1_+_171154387 7.786 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chr1_+_84647342 7.166 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_161056762 6.283 ITGB6
integrin, beta 6
chr1_-_153085963 5.128 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr2_+_102508333 4.996 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_26205437 4.924 NM_002254
KIF3C
kinesin family member 3C
chr7_+_26400503 4.872 NM_001199837
SNX10
sorting nexin 10
chr7_-_41742666 4.810 NM_002192
INHBA
inhibin, beta A
chr1_-_153013593 4.744 NM_006945
SPRR2D
small proline-rich protein 2D
chr7_+_134464417 4.734 CALD1
caldesmon 1
chr7_-_83824216 4.357 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_-_26205327 4.345 KIF3C
kinesin family member 3C
chr8_-_124553253 3.904 FBXO32
F-box protein 32
chr2_+_102314162 3.893 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr12_-_67072881 3.889 NM_001178074
NM_021150
GRIP1

glutamate receptor interacting protein 1

chr6_+_114178516 3.778 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr8_+_32504250 3.651 NM_013959
NRG1
neuregulin 1
chr7_+_134464372 3.534 CALD1
caldesmon 1
chr11_-_16424391 3.516 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr8_+_124194751 3.515 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr15_-_34610928 3.509 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr7_-_107643330 3.489 NM_002291
LAMB1
laminin, beta 1
chr2_+_102508377 3.472 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_100805415 3.409 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr14_+_85996454 3.405 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr2_-_72374919 3.377 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr6_-_30655671 3.363 NM_133471
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr8_-_7274353 3.259 NM_001205266
DEFB4B
defensin, beta 4B
chr14_-_57272344 3.222 NM_172337
OTX2
orthodenticle homeobox 2
chr2_+_210444364 3.211 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr1_+_151032880 3.203 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr12_+_53491417 3.195 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr1_-_26233367 3.184 NM_203399
STMN1
stathmin 1
chr15_-_74494780 3.169 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr22_+_31477231 3.167 NM_006932
NM_134269
NM_134270
SMTN


smoothelin


chr1_+_151032866 3.161 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_-_161056573 3.157 NM_000888
ITGB6
integrin, beta 6
chr6_+_100054649 3.129 NM_021620
PRDM13
PR domain containing 13
chr15_-_74495093 3.124 NM_001199042
NM_022369
STRA6

stimulated by retinoic acid gene 6 homolog (mouse)

chr6_+_130339715 3.119 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr10_+_102732285 3.096 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr5_+_137514416 3.086 NM_005733
KIF20A
kinesin family member 20A
chr8_+_54764367 3.014 NM_170587
RGS20
regulator of G-protein signaling 20
chr15_-_74494851 3.006 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr8_+_7752198 2.986 NM_004942
DEFB4A
defensin, beta 4A
chr1_+_151032683 2.976 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr5_+_137514753 2.964 KIF20A
kinesin family member 20A
chr2_-_31352489 2.921 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr7_+_5632435 2.909 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr12_+_53491448 2.907 IGFBP6
insulin-like growth factor binding protein 6
chr2_+_33359607 2.900 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chrX_+_135251454 2.866 NM_001159704
FHL1
four and a half LIM domains 1
chr12_-_95611023 2.865 NM_018351
FGD6
FYVE, RhoGEF and PH domain containing 6
chr7_+_5632453 2.817 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chrX_+_135251795 2.802 NM_001167819
FHL1
four and a half LIM domains 1
chr18_+_29027731 2.801 NM_001944
DSG3
desmoglein 3
chr4_+_110749149 2.791 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr17_-_49124128 2.777 NM_001251971
SPAG9
sperm associated antigen 9
chr1_+_87012758 2.777 NM_012128
CLCA4
chloride channel accessory 4
chr8_-_29206321 2.708 NM_057158
DUSP4
dual specificity phosphatase 4
chr17_+_16945766 2.704 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr2_+_169923531 2.670 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr10_+_105005643 2.646 NM_001143909
LOC729020
rcRPE
chr21_-_32931289 2.643 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr2_-_208031570 2.569 KLF7
Kruppel-like factor 7 (ubiquitous)
chr5_-_39203061 2.561 FYB
FYN binding protein
chr10_-_105845619 2.527 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr10_+_97759847 2.480 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr3_-_139258373 2.410 RBP1
retinol binding protein 1, cellular
chr3_-_139258477 2.397 RBP1
retinol binding protein 1, cellular
chr2_-_113594325 2.378 NM_000576
IL1B
interleukin 1, beta
chr4_-_47983430 2.371 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_-_17308072 2.370 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr10_+_17271302 2.348 VIM
vimentin
chr8_+_124194873 2.340 FAM83A
family with sequence similarity 83, member A
chr10_-_105845556 2.312 COL17A1
collagen, type XVII, alpha 1
chr2_-_31637598 2.262 NM_000379
XDH
xanthine dehydrogenase
chr10_+_17271276 2.258 VIM
vimentin
chr2_+_10262694 2.234 NM_001165931
RRM2
ribonucleotide reductase M2
chr18_-_29340698 2.232 NM_001034172
MCART2
mitochondrial carrier triple repeat 2
chr10_+_17271277 2.215 VIM
vimentin
chr4_+_54966197 2.194 NM_133267
GSX2
GS homeobox 2
chr14_+_23305816 2.175 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr20_+_30326903 2.140 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr10_+_17270469 2.109 VIM
vimentin
chr6_-_131291480 2.094 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr4_-_139163222 2.089 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_-_122240827 2.067


chr5_-_157002739 2.031 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr3_+_172472246 2.028 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr4_-_57547845 2.027 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chrX_-_107682600 2.023 NM_001847
COL4A6
collagen, type IV, alpha 6
chr2_+_10262853 2.000 NM_001034
RRM2
ribonucleotide reductase M2
chr14_+_23305792 1.993 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr10_+_102106771 1.988 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr2_+_62934030 1.970 NM_001142614
EHBP1
EH domain binding protein 1
chr18_+_56530677 1.958 ZNF532
zinc finger protein 532
chr3_+_39509069 1.955 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr4_-_20985547 1.954 KCNIP4
Kv channel interacting protein 4
chr2_+_228678556 1.942 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr14_+_32798478 1.939 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chrX_+_123234462 1.936 STAG2
stromal antigen 2
chr14_-_94423766 1.925 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chr11_-_64647136 1.924 EHD1
EH-domain containing 1
chr20_-_56284945 1.920 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_+_18535351 1.918 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr13_-_25745620 1.918 FAM123A
family with sequence similarity 123A
chrX_+_135229536 1.913 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr7_+_18548899 1.903 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr7_+_139528951 1.900 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr14_-_65409445 1.872 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr7_-_148581297 1.857 EZH2
enhancer of zeste homolog 2 (Drosophila)
chrX_-_153599581 1.845 FLNA
filamin A, alpha
chr10_+_54074037 1.843 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr1_-_6479880 1.842 NM_019089
HES2
hairy and enhancer of split 2 (Drosophila)
chr15_-_70390226 1.842 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr7_+_106505696 1.827 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_-_165424993 1.824 GRB14
growth factor receptor-bound protein 14
chr11_+_125496123 1.821 NM_001274
CHEK1
checkpoint kinase 1
chr3_+_19189969 1.821 NM_144633
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr11_-_61584228 1.812 FADS1
fatty acid desaturase 1
chr3_-_123339178 1.808 MYLK
myosin light chain kinase
chr16_-_75529278 1.805


chr5_+_126112847 1.795 LMNB1
lamin B1
chr2_-_2334887 1.781 NM_015025
MYT1L
myelin transcription factor 1-like
chr2_+_208576446 1.773 CCNYL1
cyclin Y-like 1
chr5_+_31193761 1.762 NM_004932
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr9_+_27109138 1.759 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr14_-_73493744 1.757 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr2_+_75061234 1.750 HK2
hexokinase 2
chr1_+_90098643 1.749 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr12_-_28124915 1.748 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr3_-_149095458 1.746 TM4SF1
transmembrane 4 L six family member 1
chr4_-_69111333 1.740 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr9_-_72287097 1.734 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr11_+_129991582 1.734 APLP2
amyloid beta (A4) precursor-like protein 2
chr5_-_16936290 1.732 MYO10
myosin X
chr7_+_28452143 1.720 NM_182898
CREB5
cAMP responsive element binding protein 5
chr13_+_111137249 1.711 COL4A2
collagen, type IV, alpha 2
chr1_-_36097137 1.708 NM_001199780
PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr7_+_80267782 1.707 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr3_-_123339423 1.703 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr12_-_8815479 1.697 MFAP5
microfibrillar associated protein 5
chr5_+_126112819 1.694 NM_001198557
LMNB1
lamin B1
chr19_-_49865638 1.692 NM_003598
TEAD2
TEA domain family member 2
chr1_-_155177685 1.663 NM_001252607
NM_001252608
NM_007112
THBS3


thrombospondin 3


chr2_-_190044330 1.655 NM_000393
COL5A2
collagen, type V, alpha 2
chr15_-_56209305 1.646 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr12_+_48876285 1.643 NM_152319
C12orf54
chromosome 12 open reading frame 54
chr4_-_57522469 1.643 NM_001145459
NM_139211
HOPX

HOP homeobox

chr1_+_84630575 1.642 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr3_+_189507448 1.637 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr6_+_12290528 1.633 NM_001168319
NM_001955
EDN1

endothelin 1

chr21_-_32201926 1.629 NM_181606
KRTAP7-1
keratin associated protein 7-1 (gene/pseudogene)
chr10_-_29754478 1.619 SVIL
supervillin
chr21_+_35190586 1.612 ITSN1
intersectin 1 (SH3 domain protein)
chr5_+_149865310 1.589 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr7_-_148581359 1.586 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr2_-_166060552 1.568 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr7_-_143059144 1.559 NM_014690
FAM131B
family with sequence similarity 131, member B
chr1_-_153067000 1.558 NM_001024209
SPRR2E
small proline-rich protein 2E
chr7_+_94297448 1.558 PEG10
paternally expressed 10
chr6_-_64029847 1.555 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr7_-_14030864 1.552 NM_001163149
ETV1
ets variant 1
chr16_+_55600583 1.550 NM_032330
CAPNS2
calpain, small subunit 2
chr12_+_93963597 1.547 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr3_+_189349215 1.539 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr8_-_124553448 1.539 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr7_-_148581377 1.536 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr13_+_78109808 1.524 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr5_-_39424930 1.518 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr2_+_208576239 1.508 NM_001142300
NM_152523
CCNYL1

cyclin Y-like 1

chr4_+_156680125 1.506 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr20_-_5591487 1.503 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr15_+_67358194 1.500 NM_005902
SMAD3
SMAD family member 3
chr11_-_71752099 1.486 NUMA1
nuclear mitotic apparatus protein 1
chr16_+_58497548 1.473 NM_020465
NDRG4
NDRG family member 4
chr19_-_42931500 1.472 NM_005357
LIPE
lipase, hormone-sensitive
chr7_-_14031049 1.469 NM_001163148
ETV1
ets variant 1
chr3_-_192635933 1.467 NM_178496
MB21D2
Mab-21 domain containing 2
chr21_+_30517897 1.463 C21orf7
chromosome 21 open reading frame 7
chr7_+_111846642 1.460 NM_021994
ZNF277
zinc finger protein 277
chr16_-_90085786 1.443 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr9_+_116342939 1.442 NM_021106
RGS3
regulator of G-protein signaling 3
chr9_-_95298251 1.436 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr17_-_7297826 1.425 PLSCR3
phospholipid scramblase 3
chr9_+_116343169 1.424 RGS3
regulator of G-protein signaling 3
chr6_+_80714389 1.418 TTK
TTK protein kinase
chrX_+_41548225 1.409 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr19_+_41257086 1.407 SNRPA
small nuclear ribonucleoprotein polypeptide A
chr5_-_114515733 1.405 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr13_-_25745778 1.401 NM_152704
NM_199138
FAM123A

family with sequence similarity 123A

chr5_-_132161863 1.392 NM_133456
SHROOM1
shroom family member 1
chr12_+_49212253 1.388 NM_000725
NM_001206915
CACNB3

calcium channel, voltage-dependent, beta 3 subunit

chr16_+_58497628 1.387 NDRG4
NDRG family member 4
chr17_-_10452939 1.386 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr3_-_119582422 1.384 GSK3B
glycogen synthase kinase 3 beta
chr15_-_70390229 1.381 NM_001105192
NM_005078
NM_020908
TLE3


transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 2.86e-13 GO:0032502 developmental process
1.34 3.12e-13 GO:0007275 multicellular organismal development
1.25 1.06e-12 GO:0032501 multicellular organismal process
1.37 5.97e-12 GO:0048731 system development
1.33 7.74e-11 GO:0048856 anatomical structure development
1.46 6.17e-08 GO:0007399 nervous system development
1.38 7.31e-08 GO:0030154 cell differentiation
1.14 1.77e-07 GO:0065007 biological regulation
1.36 1.96e-07 GO:0048869 cellular developmental process
1.24 7.66e-07 GO:0023052 signaling
1.74 4.72e-06 GO:0000904 cell morphogenesis involved in differentiation
1.81 5.26e-06 GO:0007409 axonogenesis
1.79 5.26e-06 GO:0048812 neuron projection morphogenesis
1.35 7.29e-06 GO:0048513 organ development
1.78 8.74e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.24 1.13e-05 GO:0007165 signal transduction
1.52 1.42e-05 GO:0022008 neurogenesis
1.13 1.82e-05 GO:0050789 regulation of biological process
1.72 2.06e-05 GO:0031175 neuron projection development
1.88 2.44e-05 GO:0007411 axon guidance
1.08 2.61e-05 GO:0009987 cellular process
1.23 4.57e-05 GO:0016043 cellular component organization
1.57 5.41e-05 GO:0030182 neuron differentiation
1.50 8.31e-05 GO:0040011 locomotion
1.50 1.18e-04 GO:0048699 generation of neurons
1.62 1.45e-04 GO:0048666 neuron development
1.22 1.61e-04 GO:0071840 cellular component organization or biogenesis
1.13 1.67e-04 GO:0050794 regulation of cellular process
1.60 2.07e-04 GO:0000902 cell morphogenesis
1.57 4.07e-04 GO:0032989 cellular component morphogenesis
1.35 5.94e-04 GO:0009653 anatomical structure morphogenesis
1.62 6.57e-04 GO:0032990 cell part morphogenesis
1.62 7.84e-04 GO:0048858 cell projection morphogenesis
1.25 8.65e-04 GO:0071842 cellular component organization at cellular level
1.44 9.81e-04 GO:0048468 cell development
1.49 1.31e-03 GO:0007155 cell adhesion
1.49 1.31e-03 GO:0022610 biological adhesion
1.60 1.43e-03 GO:0006935 chemotaxis
1.60 1.43e-03 GO:0042330 taxis
1.18 2.55e-03 GO:0051716 cellular response to stimulus
1.23 3.17e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.77 5.33e-03 GO:0030029 actin filament-based process
1.58 6.23e-03 GO:0007010 cytoskeleton organization
1.48 1.36e-02 GO:0030030 cell projection organization
1.12 1.67e-02 GO:0050896 response to stimulus
2.02 2.36e-02 GO:0034330 cell junction organization
1.42 4.01e-02 GO:2000026 regulation of multicellular organismal development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 2.54e-03 GO:0030054 cell junction
1.28 3.49e-03 GO:0005856 cytoskeleton
1.90 3.49e-03 GO:0030424 axon
1.67 6.29e-03 GO:0015629 actin cytoskeleton
2.08 1.12e-02 GO:0044420 extracellular matrix part
1.91 1.44e-02 GO:0005912 adherens junction
1.85 1.60e-02 GO:0070161 anchoring junction
1.60 1.77e-02 GO:0005578 proteinaceous extracellular matrix
3.08 4.71e-02 GO:0032432 actin filament bundle
1.52 4.71e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.64 1.25e-05 GO:0008092 cytoskeletal protein binding
1.11 3.61e-04 GO:0005515 protein binding
1.52 7.15e-04 GO:0005198 structural molecule activity
3.05 7.61e-04 GO:0005070 SH3/SH2 adaptor activity
1.70 1.60e-03 GO:0003779 actin binding
2.61 9.26e-03 GO:0035591 signaling adaptor activity
2.09 9.45e-03 GO:0030674 protein binding, bridging
2.02 1.75e-02 GO:0060090 binding, bridging