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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SP1.p2

Z-value: 1.856

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_-_51487070	11.779	NM_139277 NM_001207053 NM_001243126 NM_005046	KLK7	kallikrein-related peptidase 7
chr6_-_4135701	8.856	NM_001166010 NM_006117 NM_206836	ECI2	enoyl-CoA delta isomerase 2
chr8_-_144650998	8.417		C8orf73	chromosome 8 open reading frame 73
chrX_+_43514157	7.940		MAOA	monoamine oxidase A
chr19_+_54371150	7.098		MYADM	myeloid-associated differentiation marker
chr6_+_37137882	7.074	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr19_+_54371125	6.371	NM_001020819 NM_138373	MYADM	myeloid-associated differentiation marker
chr8_+_86376130	6.299	NM_000067	CA2	carbonic anhydrase II
chr9_+_131183225	6.130		CERCAM	cerebral endothelial cell adhesion molecule
chr19_+_54371170	5.953		MYADM	myeloid-associated differentiation marker
chr9_+_131183122	5.836		CERCAM	cerebral endothelial cell adhesion molecule
chr17_-_76921076	5.350		TIMP2	TIMP metallopeptidase inhibitor 2
chr10_-_15210610	5.292	NM_004808	NMT2	N-myristoyltransferase 2
chr22_-_43583132	5.262	NM_015140	TTLL12	tubulin tyrosine ligase-like family, member 12
chr20_+_31870940	5.144	NM_033197	BPIFB1	BPI fold containing family B, member 1
chr6_+_34205029	5.125		HMGA1	high mobility group AT-hook 1
chr22_-_43583058	5.080		TTLL12	tubulin tyrosine ligase-like family, member 12
chr19_-_55658310	4.936		TNNT1	troponin T type 1 (skeletal, slow)
chr8_-_144650884	4.746		C8orf73	chromosome 8 open reading frame 73
chr11_+_65686727	4.727	NM_006442	DRAP1	DR1-associated protein 1 (negative cofactor 2 alpha)
chr18_+_33877630	4.702	NM_025135	FHOD3	formin homology 2 domain containing 3
chr19_-_51472003	4.644	NM_001012964 NM_001012965	KLK6	kallikrein-related peptidase 6
chr10_+_11784355	4.556	NM_024693	ECHDC3	enoyl CoA hydratase domain containing 3
chr4_-_16085309	4.553		PROM1	prominin 1
chr6_-_30654978	4.514		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr19_+_41620336	4.513	NM_000774	CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1
chr19_-_15343767	4.487	NM_001142886	EPHX3	epoxide hydrolase 3
chr12_+_53491448	4.478		IGFBP6	insulin-like growth factor binding protein 6
chr4_-_16085666	4.445		PROM1	prominin 1
chr4_-_16085593	4.437	NM_001145847 NM_001145848	PROM1	prominin 1
chr20_+_56725982	4.427	NM_178456	C20orf85	chromosome 20 open reading frame 85
chr19_+_54372659	4.405	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr12_+_53491417	4.346	NM_002178	IGFBP6	insulin-like growth factor binding protein 6
chr21_-_44495894	4.343	NM_000071	CBS	cystathionine-beta-synthase
chr1_-_20812727	4.279	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_-_76183074	4.181	NM_003258	TK1	thymidine kinase 1, soluble
chr21_-_44496423	4.177	NM_001178008 NM_001178009	CBS	cystathionine-beta-synthase
chr19_-_51504799	4.156	NM_007196 NM_144505 NM_144506 NM_144507	KLK8	kallikrein-related peptidase 8
chr15_+_80445177	4.069	NM_000137	FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr6_+_34204928	4.012		HMGA1	high mobility group AT-hook 1
chr9_+_139560193	3.982	NM_201446	EGFL7	EGF-like-domain, multiple 7
chr3_-_50336662	3.935	NM_001200016 NM_012191 NM_001200030 NM_001200031 NM_001200032 NM_003549	NAT6 HYAL3	N-acetyltransferase 6 (GCN5-related) hyaluronoglucosaminidase 3
chr1_-_20812271	3.935		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_+_80574853	3.881	NM_130897	DYNLRB2	dynein, light chain, roadblock-type 2
chr1_-_6557448	3.879		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chrX_-_134232663	3.853		LINC00087	long intergenic non-protein coding RNA 87
chr9_+_131182690	3.841	NM_016174	CERCAM	cerebral endothelial cell adhesion molecule
chr9_+_72435730	3.837	NM_001010940	C9orf135	chromosome 9 open reading frame 135
chr2_-_216300770	3.820	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr19_-_41859830	3.760	NM_000660	TGFB1	transforming growth factor, beta 1
chr1_-_6545521	3.750		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_+_150632612	3.739	NM_000405 NM_001167607	GM2A	GM2 ganglioside activator
chr22_-_30685485	3.618	NM_001037666	GATSL3	GATS protein-like 3
chr16_-_90085786	3.608	NM_001042610	DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1
chr15_+_80445340	3.586		FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr1_+_182992329	3.585	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chrX_-_153775427	3.486		G6PD	glucose-6-phosphate dehydrogenase
chr19_+_30302861	3.477	NM_001238	CCNE1	cyclin E1
chr6_-_30655078	3.453	NM_001134870	PPP1R18	protein phosphatase 1, regulatory subunit 18
chr2_+_64681610	3.416		LGALSL	lectin, galactoside-binding-like
chr11_-_66725790	3.415	NM_000920 NM_001040716	PC	pyruvate carboxylase
chr5_+_10441973	3.413	NM_001201466 NM_031916	ROPN1L	rhophilin associated tail protein 1-like
chr3_-_53290099	3.385	NM_001064 NM_001135055	TKT	transketolase
chr21_-_47648672	3.374		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr9_-_123639566	3.373	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr9_+_139560243	3.361		EGFL7	EGF-like-domain, multiple 7
chr2_-_235405692	3.327	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr17_+_79989485	3.302	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr21_-_47648715	3.295	NM_001001438 NM_001145436 NM_001145437 NM_002340	LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr17_-_17726855	3.292		SREBF1	sterol regulatory element binding transcription factor 1
chr19_-_51472816	3.276	NM_002774	KLK6	kallikrein-related peptidase 6
chr17_+_1633754	3.273		WDR81	WD repeat domain 81
chr1_-_6321034	3.270	NM_207370	GPR153	G protein-coupled receptor 153
chr19_-_41859519	3.237		TGFB1	transforming growth factor, beta 1
chr22_+_31477231	3.233	NM_006932 NM_134269 NM_134270	SMTN	smoothelin
chr7_+_77166331	3.203		PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr11_+_65686908	3.193		DRAP1	DR1-associated protein 1 (negative cofactor 2 alpha)
chr10_+_22634373	3.177	NM_001253854 NM_001253855 NM_012443 NM_172242	SPAG6	sperm associated antigen 6
chr7_-_98741375	3.149		SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr16_+_66638652	3.127		CMTM3	CKLF-like MARVEL transmembrane domain containing 3
chr2_+_24272583	3.120	NM_004116 NM_054033	FKBP1B	FK506 binding protein 1B, 12.6 kDa
chrX_+_134555867	3.113		LINC00086	long intergenic non-protein coding RNA 86
chr6_-_32551993	3.080		HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr19_-_11689591	3.074	NM_001111034	ACP5	acid phosphatase 5, tartrate resistant
chr9_-_123639462	3.073		PHF19	PHD finger protein 19
chr7_-_128050006	3.035	NM_000883 NM_001102605 NM_001142576 NM_183243	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr8_+_26371461	3.010	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr2_+_24272627	3.009		FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr21_-_44846927	3.004	NM_173354	SIK1	salt-inducible kinase 1
chr22_-_36784001	3.002		MYH9	myosin, heavy chain 9, non-muscle
chrX_+_30671602	2.996		GK	glycerol kinase
chr9_-_34397786	2.991	NM_032596	C9orf24	chromosome 9 open reading frame 24
chr4_-_819879	2.981	NM_006651	CPLX1	complexin 1
chr22_+_31487315	2.962		SMTN	smoothelin
chr3_-_197686837	2.942	NM_032263	IQCG	IQ motif containing G
chr19_-_42928152	2.939		LIPE	lipase, hormone-sensitive
chr6_-_131384321	2.934		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr3_-_197676755	2.927	NM_001134435	IQCG	IQ motif containing G
chr17_-_76921205	2.924		TIMP2	TIMP metallopeptidase inhibitor 2
chr17_-_882905	2.923	NM_022463	NXN	nucleoredoxin
chr20_+_34203746	2.894	NM_003116	SPAG4	sperm associated antigen 4
chr10_+_63422718	2.888	NM_173554	C10orf107	chromosome 10 open reading frame 107
chr3_-_52567708	2.887	NM_001134231	NT5DC2	5'-nucleotidase domain containing 2
chr3_-_52567809	2.886		NT5DC2	5'-nucleotidase domain containing 2
chr3_-_48130283	2.877		MAP4	microtubule-associated protein 4
chr11_-_62314199	2.873		AHNAK	AHNAK nucleoprotein
chr3_-_13921617	2.853	NM_004625	WNT7A	wingless-type MMTV integration site family, member 7A
chr9_-_138391696	2.852	NM_001048265 NM_144654	C9orf116	chromosome 9 open reading frame 116
chr1_-_26232643	2.851	NM_203401	STMN1	stathmin 1
chr2_-_208031570	2.847		KLF7	Kruppel-like factor 7 (ubiquitous)
chr11_+_61595633	2.839	NM_004265	FADS2	fatty acid desaturase 2
chr14_+_94640648	2.836	NM_020958 NM_058237	PPP4R4	protein phosphatase 4, regulatory subunit 4
chr9_+_128509616	2.835	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr21_-_47648618	2.829		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr11_-_568419	2.820		MIR210HG	MIR210 host gene (non-protein coding)
chr20_+_25228698	2.818	NM_002862	PYGB	phosphorylase, glycogen; brain
chr7_-_128045995	2.811	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr1_-_204121144	2.792	NM_018208	ETNK2	ethanolamine kinase 2
chr7_-_143059696	2.770	NM_001031690	FAM131B	family with sequence similarity 131, member B
chr1_+_233463513	2.762	NM_032435	KIAA1804	mixed lineage kinase 4
chr21_-_47648685	2.760		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr2_+_64681270	2.757	NM_014181	LGALSL	lectin, galactoside-binding-like
chrX_+_30671537	2.739		GK	glycerol kinase
chr2_+_106682111	2.725	NM_032411	C2orf40	chromosome 2 open reading frame 40
chr7_+_143078358	2.724	NM_001010972 NM_003461	ZYX	zyxin
chr1_-_204120909	2.715		ETNK2	ethanolamine kinase 2
chr20_+_62371218	2.715		SLC2A4RG	SLC2A4 regulator
chr1_+_15736422	2.706		EFHD2	EF-hand domain family, member D2
chr3_-_128840856	2.705	NM_001204884 NM_001204883	RAB43	RAB43, member RAS oncogene family
chr19_+_45349560	2.694		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr7_-_143059144	2.686	NM_014690	FAM131B	family with sequence similarity 131, member B
chr19_+_41594367	2.659	NM_000766	CYP2A13	cytochrome P450, family 2, subfamily A, polypeptide 13
chr7_+_48075107	2.638	NM_001100159	C7orf57	chromosome 7 open reading frame 57
chr3_-_50340979	2.636	NM_007312 NM_033159 NM_153282 NM_153283 NM_153285	HYAL1	hyaluronoglucosaminidase 1
chr2_-_9143742	2.635	NM_138799	MBOAT2	membrane bound O-acyltransferase domain containing 2
chr1_+_15736387	2.615	NM_024329	EFHD2	EF-hand domain family, member D2
chr12_+_70759974	2.597	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr19_-_10679328	2.592		CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chrX_-_153599719	2.588		FLNA	filamin A, alpha
chr15_-_30114336	2.578		TJP1	tight junction protein 1 (zona occludens 1)
chr7_+_48128939	2.574		UPP1	uridine phosphorylase 1
chr6_+_31126340	2.555		TCF19	transcription factor 19
chr3_-_128840605	2.538	NM_001204886 NM_001204887 NM_001204888 NM_198490 NM_001204885	RAB43	RAB43, member RAS oncogene family
chr19_+_16187266	2.538		TPM4	tropomyosin 4
chr11_+_101918168	2.538	NM_001195005 NM_032930	C11orf70	chromosome 11 open reading frame 70
chr7_+_48128738	2.534	NM_003364	UPP1	uridine phosphorylase 1
chr14_-_21270537	2.532	NM_198232	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)
chr22_-_36783851	2.529		MYH9	myosin, heavy chain 9, non-muscle
chr19_+_4910339	2.521	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr12_-_71551778	2.519	NM_004616	TSPAN8	tetraspanin 8
chr2_+_23608297	2.508	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr15_-_56757239	2.493	NM_018365	MNS1	meiosis-specific nuclear structural 1
chr12_+_49297892	2.487	NM_033124	CCDC65	coiled-coil domain containing 65
chr6_-_131384387	2.485	NM_001135554 NM_001135555 NM_001199388 NM_001431	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr1_+_46713385	2.476		RAD54L	RAD54-like (S. cerevisiae)
chr7_+_143078608	2.471		ZYX	zyxin
chr12_-_71551564	2.469		TSPAN8	tetraspanin 8
chr12_-_109125275	2.464		CORO1C	coronin, actin binding protein, 1C
chr7_+_143078399	2.461		ZYX	zyxin
chr19_-_50143350	2.461	NM_006270	RRAS	related RAS viral (r-ras) oncogene homolog
chr8_-_25315941	2.461	NM_017634	KCTD9	potassium channel tetramerisation domain containing 9
chr12_-_125348266	2.455		SCARB1	scavenger receptor class B, member 1
chr16_-_87903028	2.446	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr2_-_72374919	2.444	NM_019885	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr9_-_33167084	2.443		B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr6_-_24911194	2.436	NM_014722	FAM65B	family with sequence similarity 65, member B
chr12_-_120554551	2.436		RAB35	RAB35, member RAS oncogene family
chr19_-_16582810	2.435		EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1
chrX_+_106449861	2.435	NM_001169154 NM_173494	CXorf41	chromosome X open reading frame 41
chr6_+_31126114	2.418	NM_001077511 NM_007109	TCF19	transcription factor 19
chr8_+_22022644	2.417	NM_001199 NM_006129	BMP1	bone morphogenetic protein 1
chr10_+_121485593	2.416		INPP5F	inositol polyphosphate-5-phosphatase F
chr19_+_2096930	2.414		IZUMO4	IZUMO family member 4
chr2_-_130902568	2.411	NM_207310	CCDC74B	coiled-coil domain containing 74B
chr6_+_151815174	2.409	NM_025059	C6orf97	chromosome 6 open reading frame 97
chr16_+_66638530	2.405	NM_181553	CMTM3	CKLF-like MARVEL transmembrane domain containing 3
chr5_+_156696351	2.399	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr1_+_37940180	2.389		ZC3H12A	zinc finger CCCH-type containing 12A
chr19_+_54369610	2.385	NM_001020820	MYADM	myeloid-associated differentiation marker
chr1_+_78956727	2.383	NM_000959 NM_001039585	PTGFR	prostaglandin F receptor (FP)
chr16_+_58497548	2.383	NM_020465	NDRG4	NDRG family member 4
chr10_-_101380160	2.380		SLC25A28	solute carrier family 25, member 28
chr10_+_102106771	2.378	NM_005063	SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr1_+_37940074	2.376	NM_025079	ZC3H12A	zinc finger CCCH-type containing 12A
chr19_-_19051112	2.375	NM_001145722 NM_001145721	HOMER3	homer homolog 3 (Drosophila)
chr1_+_182992694	2.373
chr1_+_37940129	2.365		ZC3H12A	zinc finger CCCH-type containing 12A
chr19_+_8429010	2.365	NM_001039667 NM_139314	ANGPTL4	angiopoietin-like 4
chr7_+_48128225	2.363	NM_181597	UPP1	uridine phosphorylase 1
chr10_-_17659365	2.362	NM_014241	PTPLA	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr19_+_16187306	2.351		TPM4	tropomyosin 4
chr14_-_53417636	2.349		FERMT2	fermitin family member 2
chr19_+_2096792	2.348	NM_001031735 NM_001039846	IZUMO4	IZUMO family member 4
chr7_+_105603656	2.345	NM_152750	CDHR3	cadherin-related family member 3
chr17_-_34329083	2.342	NM_032965	CCL15	chemokine (C-C motif) ligand 15
chr9_+_103235634	2.337		TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_+_119076974	2.333	NM_005188	CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr22_-_50946020	2.323		LMF2	lipase maturation factor 2
chr4_+_1723212	2.323	NM_006342	TACC3	transforming, acidic coiled-coil containing protein 3
chr19_-_41859332	2.315		TGFB1	transforming growth factor, beta 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.09	3.14e-32	GO:0009987	cellular process
1.14	8.79e-26	GO:0044237	cellular metabolic process
1.12	2.10e-22	GO:0008152	metabolic process
1.11	2.66e-21	GO:0065007	biological regulation
1.11	3.01e-21	GO:0050789	regulation of biological process
1.12	4.10e-21	GO:0050794	regulation of cellular process
1.12	1.25e-18	GO:0044238	primary metabolic process
1.15	4.33e-18	GO:0044260	cellular macromolecule metabolic process
1.13	6.04e-16	GO:0043170	macromolecule metabolic process
1.19	1.90e-11	GO:0048523	negative regulation of cellular process
1.17	2.40e-11	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15	4.52e-11	GO:0060255	regulation of macromolecule metabolic process
1.18	1.08e-10	GO:0048519	negative regulation of biological process
1.14	3.63e-10	GO:0016043	cellular component organization
1.14	5.09e-10	GO:0031323	regulation of cellular metabolic process
1.17	6.57e-10	GO:0048522	positive regulation of cellular process
1.14	6.71e-10	GO:0006807	nitrogen compound metabolic process
1.14	1.08e-09	GO:0080090	regulation of primary metabolic process
1.14	1.14e-09	GO:0034641	cellular nitrogen compound metabolic process
1.13	1.19e-09	GO:0019222	regulation of metabolic process
1.14	1.23e-09	GO:0071840	cellular component organization or biogenesis
1.13	3.71e-09	GO:0023052	signaling
1.21	1.71e-08	GO:0009966	regulation of signal transduction
1.15	3.78e-08	GO:0048518	positive regulation of biological process
1.19	4.90e-08	GO:0023051	regulation of signaling
1.13	9.03e-08	GO:0007165	signal transduction
1.12	9.88e-08	GO:0051179	localization
1.24	1.26e-07	GO:0032268	regulation of cellular protein metabolic process
1.18	1.42e-07	GO:0006464	protein modification process
1.15	2.83e-07	GO:0044267	cellular protein metabolic process
1.11	2.97e-07	GO:0051716	cellular response to stimulus
1.14	8.41e-07	GO:0071842	cellular component organization at cellular level
1.23	8.89e-07	GO:0051246	regulation of protein metabolic process
1.17	1.73e-06	GO:0010467	gene expression
1.13	2.05e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.15	5.02e-06	GO:0090304	nucleic acid metabolic process
1.17	5.62e-06	GO:0016070	RNA metabolic process
1.16	5.79e-06	GO:0043412	macromolecule modification
1.25	6.04e-06	GO:0031399	regulation of protein modification process
1.12	1.38e-05	GO:0019538	protein metabolic process
1.12	1.90e-05	GO:0051234	establishment of localization
1.16	2.32e-05	GO:0048583	regulation of response to stimulus
1.19	3.47e-05	GO:0051641	cellular localization
1.13	4.34e-05	GO:0010468	regulation of gene expression
1.34	6.80e-05	GO:0007264	small GTPase mediated signal transduction
1.19	6.88e-05	GO:0031325	positive regulation of cellular metabolic process
1.43	7.91e-05	GO:0051129	negative regulation of cellular component organization
1.13	8.16e-05	GO:0051252	regulation of RNA metabolic process
1.23	8.29e-05	GO:0051128	regulation of cellular component organization
1.26	8.63e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.29	8.68e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.12	9.38e-05	GO:0006810	transport
1.23	9.78e-05	GO:0033554	cellular response to stress
1.12	1.00e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.26	1.12e-04	GO:0001932	regulation of protein phosphorylation
1.13	1.14e-04	GO:0044249	cellular biosynthetic process
1.19	1.22e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.19	1.43e-04	GO:0044248	cellular catabolic process
1.12	1.71e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	1.86e-04	GO:0006351	transcription, DNA-dependent
1.16	1.90e-04	GO:0006996	organelle organization
1.18	2.13e-04	GO:0009893	positive regulation of metabolic process
1.13	2.55e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.23	2.74e-04	GO:0046907	intracellular transport
1.21	2.85e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.42	3.21e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.20	4.26e-04	GO:0006793	phosphorus metabolic process
1.20	4.26e-04	GO:0006796	phosphate metabolic process
1.12	4.54e-04	GO:0031326	regulation of cellular biosynthetic process
1.12	4.74e-04	GO:0009058	biosynthetic process
1.23	4.81e-04	GO:0016192	vesicle-mediated transport
1.15	5.19e-04	GO:0034645	cellular macromolecule biosynthetic process
1.17	6.43e-04	GO:0033036	macromolecule localization
1.11	6.47e-04	GO:0009889	regulation of biosynthetic process
1.31	7.34e-04	GO:0006397	mRNA processing
1.23	7.54e-04	GO:0019220	regulation of phosphate metabolic process
1.23	7.54e-04	GO:0051174	regulation of phosphorus metabolic process
1.30	7.85e-04	GO:0009968	negative regulation of signal transduction
1.24	8.09e-04	GO:0042325	regulation of phosphorylation
1.13	8.20e-04	GO:0065008	regulation of biological quality
1.55	8.51e-04	GO:0007265	Ras protein signal transduction
1.27	8.94e-04	GO:0051338	regulation of transferase activity
1.12	1.10e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.19	1.10e-03	GO:0010646	regulation of cell communication
1.19	1.60e-03	GO:0032774	RNA biosynthetic process
1.12	1.66e-03	GO:0006355	regulation of transcription, DNA-dependent
1.16	1.74e-03	GO:0035556	intracellular signal transduction
1.19	1.78e-03	GO:0009892	negative regulation of metabolic process
1.14	1.86e-03	GO:0009059	macromolecule biosynthetic process
1.27	2.46e-03	GO:0045859	regulation of protein kinase activity
1.26	3.08e-03	GO:0048585	negative regulation of response to stimulus
1.25	3.65e-03	GO:0016071	mRNA metabolic process
1.19	3.99e-03	GO:0022008	neurogenesis
1.18	4.03e-03	GO:0008104	protein localization
1.17	4.28e-03	GO:0051649	establishment of localization in cell
1.15	5.17e-03	GO:0009653	anatomical structure morphogenesis
1.23	5.39e-03	GO:0051726	regulation of cell cycle
1.15	5.68e-03	GO:0009056	catabolic process
1.49	5.90e-03	GO:0022604	regulation of cell morphogenesis
1.26	6.39e-03	GO:0043549	regulation of kinase activity
1.19	6.53e-03	GO:0048699	generation of neurons
1.53	6.83e-03	GO:0031098	stress-activated protein kinase signaling cascade
1.09	6.96e-03	GO:0032502	developmental process
1.49	8.88e-03	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.17	9.90e-03	GO:0042981	regulation of apoptosis
1.18	1.03e-02	GO:0031324	negative regulation of cellular metabolic process
1.18	1.05e-02	GO:0032879	regulation of localization
1.26	1.10e-02	GO:0010648	negative regulation of cell communication
1.19	1.25e-02	GO:0008219	cell death
1.16	1.26e-02	GO:0050790	regulation of catalytic activity
1.17	1.29e-02	GO:0043067	regulation of programmed cell death
1.32	1.43e-02	GO:0071900	regulation of protein serine/threonine kinase activity
1.45	1.60e-02	GO:0006184	GTP catabolic process
1.30	1.74e-02	GO:0009259	ribonucleotide metabolic process
1.17	1.85e-02	GO:0010941	regulation of cell death
1.43	1.92e-02	GO:0031344	regulation of cell projection organization
1.20	1.98e-02	GO:0012501	programmed cell death
1.17	2.06e-02	GO:0007049	cell cycle
1.22	2.19e-02	GO:0042060	wound healing
1.14	2.20e-02	GO:0065009	regulation of molecular function
1.30	2.22e-02	GO:0009150	purine ribonucleotide metabolic process
1.26	2.26e-02	GO:0023057	negative regulation of signaling
1.17	2.40e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.18	2.42e-02	GO:0016265	death
1.24	2.46e-02	GO:0048858	cell projection morphogenesis
1.09	2.53e-02	GO:0007275	multicellular organismal development
1.14	2.61e-02	GO:0007399	nervous system development
1.25	2.80e-02	GO:0061024	membrane organization
1.25	2.81e-02	GO:0016044	cellular membrane organization
1.33	2.81e-02	GO:0030036	actin cytoskeleton organization
1.30	2.89e-02	GO:0060284	regulation of cell development
1.24	3.01e-02	GO:0006753	nucleoside phosphate metabolic process
1.24	3.01e-02	GO:0009117	nucleotide metabolic process
1.42	3.07e-02	GO:0046039	GTP metabolic process
1.22	3.22e-02	GO:0000902	cell morphogenesis
1.20	3.34e-02	GO:0051254	positive regulation of RNA metabolic process
1.12	3.48e-02	GO:0044281	small molecule metabolic process
1.23	3.75e-02	GO:0032990	cell part morphogenesis
1.33	3.79e-02	GO:0000165	MAPKKK cascade
1.28	3.95e-02	GO:0051301	cell division
1.22	4.61e-02	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.30	4.65e-02	GO:0030029	actin filament-based process
1.46	4.68e-02	GO:0010975	regulation of neuron projection development
1.23	4.90e-02	GO:0007010	cytoskeleton organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	3.88e-53	GO:0005622	intracellular
1.10	1.15e-52	GO:0044424	intracellular part
1.13	1.90e-42	GO:0005737	cytoplasm
1.12	3.88e-35	GO:0043227	membrane-bounded organelle
1.12	3.90e-35	GO:0043231	intracellular membrane-bounded organelle
1.10	6.66e-34	GO:0043229	intracellular organelle
1.10	1.47e-33	GO:0043226	organelle
1.15	8.87e-28	GO:0044444	cytoplasmic part
1.13	6.41e-20	GO:0044446	intracellular organelle part
1.13	9.71e-19	GO:0044422	organelle part
1.22	6.12e-17	GO:0005829	cytosol
1.11	4.46e-14	GO:0005634	nucleus
1.19	4.09e-13	GO:0031974	membrane-enclosed lumen
1.18	4.29e-12	GO:0043233	organelle lumen
1.18	6.20e-12	GO:0070013	intracellular organelle lumen
1.18	3.07e-11	GO:0044428	nuclear part
1.17	8.16e-10	GO:0031090	organelle membrane
1.22	1.41e-09	GO:0005654	nucleoplasm
1.03	2.09e-09	GO:0044464	cell part
1.03	2.39e-09	GO:0005623	cell
1.18	2.39e-09	GO:0031981	nuclear lumen
1.11	2.59e-07	GO:0032991	macromolecular complex
1.12	5.23e-07	GO:0043234	protein complex
1.16	6.57e-06	GO:0012505	endomembrane system
1.19	3.57e-05	GO:0005783	endoplasmic reticulum
1.22	1.65e-04	GO:0031975	envelope
1.22	1.75e-04	GO:0031967	organelle envelope
1.18	2.85e-04	GO:0005794	Golgi apparatus
1.21	8.25e-04	GO:0044451	nucleoplasm part
1.26	9.65e-04	GO:0005768	endosome
1.19	4.59e-03	GO:0031410	cytoplasmic vesicle
1.32	4.64e-03	GO:0044440	endosomal part
1.19	7.33e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.31	8.23e-03	GO:0010008	endosome membrane
1.18	1.41e-02	GO:0044432	endoplasmic reticulum part
1.17	1.49e-02	GO:0031982	vesicle
1.18	1.58e-02	GO:0031988	membrane-bounded vesicle
1.20	2.46e-02	GO:0044431	Golgi apparatus part
1.72	3.68e-02	GO:0008287	protein serine/threonine phosphatase complex
1.21	4.80e-02	GO:0005740	mitochondrial envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	2.84e-36	GO:0005515	protein binding
1.07	2.54e-29	GO:0005488	binding
1.39	1.50e-09	GO:0019904	protein domain specific binding
1.16	2.60e-09	GO:0000166	nucleotide binding
1.09	1.37e-08	GO:0003824	catalytic activity
1.16	8.61e-07	GO:0032553	ribonucleotide binding
1.16	8.61e-07	GO:0032555	purine ribonucleotide binding
1.16	1.47e-06	GO:0017076	purine nucleotide binding
1.16	2.41e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.15	2.52e-04	GO:0032559	adenyl ribonucleotide binding
1.15	3.15e-04	GO:0030554	adenyl nucleotide binding
1.19	4.38e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.14	5.34e-04	GO:0016740	transferase activity
1.15	7.17e-04	GO:0005524	ATP binding
1.20	7.65e-04	GO:0016301	kinase activity
1.20	1.84e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.26	4.00e-03	GO:0004674	protein serine/threonine kinase activity
1.21	7.53e-03	GO:0004672	protein kinase activity
1.23	1.71e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.18	1.75e-02	GO:0019899	enzyme binding
1.46	2.26e-02	GO:0017124	SH3 domain binding
1.21	3.51e-02	GO:0008092	cytoskeletal protein binding
1.22	4.17e-02	GO:0030695	GTPase regulator activity