Motif ID: SPIB.p2

Z-value: 1.942


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPIBchr19_+_509221940.144.7e-01Click!


Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_113885145 9.707 IL1RN
interleukin 1 receptor antagonist
chr2_+_113885137 9.342 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr19_-_51472003 8.288 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr19_-_51472816 7.289 NM_002774
KLK6
kallikrein-related peptidase 6
chr12_+_4382882 6.274 NM_001759
CCND2
cyclin D2
chr10_+_102107074 5.677 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr10_+_102107001 5.274 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_+_40610940 4.953 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr10_+_102107256 4.754


chr17_+_40610897 4.693 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_+_40610875 4.648 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr12_-_89746238 4.583 DUSP6
dual specificity phosphatase 6
chr17_+_2699731 4.569 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr19_+_35645614 4.290 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_89745997 4.220 DUSP6
dual specificity phosphatase 6
chr12_-_89746244 4.200 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr19_-_41859253 4.179 TGFB1
transforming growth factor, beta 1
chr17_+_40610905 4.165 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_+_40610857 4.083 NM_001130020
NM_001130021
NM_005177
ATP6V0A1


ATPase, H+ transporting, lysosomal V0 subunit a1


chr10_+_102106958 3.958 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr8_+_7752198 3.882 NM_004942
DEFB4A
defensin, beta 4A
chr19_-_43031343 3.799 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr2_-_31440378 3.653 NM_001145122
CAPN14
calpain 14
chr2_-_192015733 3.594 STAT4
signal transducer and activator of transcription 4
chr17_+_7942351 3.398 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr12_+_47610244 3.383 FAM113B
family with sequence similarity 113, member B
chr17_+_40610915 3.362 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr11_-_58343308 3.265 NM_004811
LPXN
leupaxin
chr10_+_102121371 3.236 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr2_-_69098502 3.165 NM_014482
BMP10
bone morphogenetic protein 10
chr6_+_130339715 3.055 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr2_+_233925104 3.047 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr17_+_40610899 3.030 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr7_+_143079354 2.953 ZYX
zyxin
chr1_-_24469571 2.916 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chrX_+_69509878 2.897 NM_012310
KIF4A
kinesin family member 4A
chr1_-_20812271 2.830 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_-_41859519 2.824 TGFB1
transforming growth factor, beta 1
chr6_-_30654978 2.802 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr2_-_31352489 2.747 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_-_41859332 2.720 TGFB1
transforming growth factor, beta 1
chr11_+_118827007 2.701 NM_006760
UPK2
uroplakin 2
chr1_+_84609941 2.698 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_51845377 2.657 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr19_-_36019194 2.638 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr7_-_23509972 2.539 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_192016293 2.533 NM_001243835
STAT4
signal transducer and activator of transcription 4
chr5_-_127873734 2.525 NM_001999
FBN2
fibrillin 2
chr1_+_206138909 2.488 NM_001123168
FAM72B
FAM72A
family with sequence similarity 72, member B
family with sequence similarity 72, member A
chr19_-_41859830 2.483 NM_000660
TGFB1
transforming growth factor, beta 1
chr10_+_102106771 2.440 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr2_+_239756672 2.435 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr21_+_30517897 2.394 C21orf7
chromosome 21 open reading frame 7
chr2_+_233925035 2.372 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr3_+_136537860 2.333 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr1_+_24645811 2.332 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr12_-_122240827 2.296


chr11_-_64851556 2.294 NM_080668
CDCA5
cell division cycle associated 5
chr12_+_47610051 2.272 NM_138371
FAM113B
family with sequence similarity 113, member B
chr8_-_23177481 2.235 LOXL2
lysyl oxidase-like 2
chr8_+_26435920 2.205 NM_001244604
DPYSL2
dihydropyrimidinase-like 2
chr1_+_24645914 2.168 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_39553796 2.151 NM_002277
KRT31
keratin 31
chr1_-_20812727 2.150 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_54371150 2.144 MYADM
myeloid-associated differentiation marker
chr14_-_75422466 2.129 NM_001207012
NM_002632
PGF

placental growth factor

chr10_+_99400441 2.123 NM_018425
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr19_+_10381516 2.112 NM_000201
ICAM1
intercellular adhesion molecule 1
chr12_-_76425375 2.110 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr16_+_8806825 2.107 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr8_-_7274353 2.097 NM_001205266
DEFB4B
defensin, beta 4B
chr22_-_36236264 2.082 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr13_-_20805371 2.073 NM_006783
GJB6
gap junction protein, beta 6, 30kDa
chr15_-_72598655 2.065 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr11_-_64851449 2.050 CDCA5
cell division cycle associated 5
chr10_-_33623978 2.030 NRP1
neuropilin 1
chr8_+_22462267 2.029 KIAA1967
KIAA1967
chr14_-_69354900 2.027 ACTN1
actinin, alpha 1
chr15_+_74833517 1.981 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr6_-_41130820 1.977 TREM2
triggering receptor expressed on myeloid cells 2
chr5_+_96211643 1.962 NM_001130140
NM_022350
ERAP2

endoplasmic reticulum aminopeptidase 2

chr3_-_12800739 1.956 NM_018306
TMEM40
transmembrane protein 40
chr14_-_64194692 1.949 NM_030791
SGPP1
sphingosine-1-phosphate phosphatase 1
chr10_+_99400469 1.948 PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr6_+_106534188 1.920 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr16_+_30194925 1.898 CORO1A
coronin, actin binding protein, 1A
chr12_-_6745087 1.897 NM_020400
LPAR5
lysophosphatidic acid receptor 5
chr2_-_113542970 1.896 NM_000575
IL1A
interleukin 1, alpha
chr19_+_54371125 1.895 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr2_+_102508333 1.882 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_210444364 1.871 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr8_+_124194751 1.868 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr12_-_76425207 1.856 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr4_-_57547845 1.836 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr19_+_41725098 1.825 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr12_-_54813002 1.811 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr8_-_124408665 1.811 ATAD2
ATPase family, AAA domain containing 2
chr2_+_113239812 1.809 TTL
tubulin tyrosine ligase
chr6_+_31126114 1.793 NM_001077511
NM_007109
TCF19

transcription factor 19

chr2_+_102953716 1.776 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr9_+_27109138 1.767 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr22_-_37640187 1.762 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_+_31553955 1.759 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr11_-_118966103 1.755 H2AFX
H2A histone family, member X
chr6_-_41130864 1.754 TREM2
triggering receptor expressed on myeloid cells 2
chr2_-_216300770 1.754 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr7_+_134464417 1.737 CALD1
caldesmon 1
chr1_-_162381805 1.733 NM_053282
SH2D1B
SH2 domain containing 1B
chr1_+_152881022 1.721 NM_005547
IVL
involucrin
chr11_-_28129701 1.720 NM_031217
KIF18A
kinesin family member 18A
chr19_+_54371170 1.712 MYADM
myeloid-associated differentiation marker
chr20_+_361938 1.707 TRIB3
tribbles homolog 3 (Drosophila)
chr6_+_116782555 1.704 NM_001010919
FAM26F
family with sequence similarity 26, member F
chr2_+_28616360 1.701 FOSL2
FOS-like antigen 2
chr5_+_86563594 1.692 RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr12_-_57634474 1.686 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr15_+_93447702 1.680 CHD2
chromodomain helicase DNA binding protein 2
chr22_-_36236330 1.668 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr9_+_116343169 1.655 RGS3
regulator of G-protein signaling 3
chr2_-_42991201 1.651 NM_148962
OXER1
oxoeicosanoid (OXE) receptor 1
chr10_-_33623771 1.627 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr1_-_153029987 1.625 NM_005988
SPRR2A
small proline-rich protein 2A
chr9_-_107690526 1.613 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr22_-_37640287 1.612 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_+_38810461 1.608 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr1_-_155948206 1.601 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr9_+_116342939 1.592 NM_021106
RGS3
regulator of G-protein signaling 3
chr12_+_56915587 1.575 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr12_+_120105656 1.552 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_-_149908098 1.551 NM_181873
MTMR11
myotubularin related protein 11
chr11_-_118966175 1.546 NM_002105
H2AFX
H2A histone family, member X
chr15_-_59665069 1.531 NM_004998
MYO1E
myosin IE
chr19_+_38810540 1.518 KCNK6
potassium channel, subfamily K, member 6
chr11_-_64647136 1.517 EHD1
EH-domain containing 1
chr12_-_48499840 1.509 SENP1
SUMO1/sentrin specific peptidase 1
chr19_-_14887623 1.467 EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr8_+_22022677 1.463 BMP1
bone morphogenetic protein 1
chr12_+_53442732 1.455 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_40428672 1.448 NM_001248
ENTPD3
ectonucleoside triphosphate diphosphohydrolase 3
chr8_-_101964248 1.442 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr2_+_28616346 1.436 FOSL2
FOS-like antigen 2
chr1_-_43855448 1.434 MED8
mediator complex subunit 8
chr15_-_73661141 1.427 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr7_+_106505696 1.422 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr6_-_30652434 1.416 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr12_+_53443834 1.406 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr11_-_117166247 1.398 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr12_-_48152180 1.397 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr22_-_36236421 1.395 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr4_-_103998169 1.395 NM_178833
SLC9B2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
chr1_-_155948317 1.389 NM_001162383
NM_001162384
ARHGEF2

Rho/Rac guanine nucleotide exchange factor (GEF) 2

chr8_+_22022872 1.384 BMP1
bone morphogenetic protein 1
chr12_+_1800146 1.382 ADIPOR2
adiponectin receptor 2
chr12_-_53242716 1.381 NM_173352
KRT78
keratin 78
chr1_-_153521717 1.378 NM_002960
S100A3
S100 calcium binding protein A3
chr11_-_28129687 1.374 KIF18A
kinesin family member 18A
chr6_+_15246299 1.365 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr11_+_61560401 1.365 FEN1
flap structure-specific endonuclease 1
chr6_+_12290528 1.364 NM_001168319
NM_001955
EDN1

endothelin 1

chr1_-_231560789 1.361 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr8_-_101964334 1.361 NM_145690
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr10_+_91498724 1.360 KIF20B
kinesin family member 20B
chr11_-_28129646 1.358 KIF18A
kinesin family member 18A
chr2_-_238322770 1.346 COL6A3
collagen, type VI, alpha 3
chrX_-_48815582 1.342 OTUD5
OTU domain containing 5
chr6_-_41130921 1.335 NM_018965
TREM2
triggering receptor expressed on myeloid cells 2
chr13_+_98605928 1.312 NM_002271
IPO5
importin 5
chr5_-_59995938 1.312 NM_001145208
NM_018369
DEPDC1B

DEP domain containing 1B

chr1_+_120839004 1.310 NM_001100910
FAM72B
family with sequence similarity 72, member B
chr21_+_41029253 1.309 NM_006057
NM_033170
NM_033171
NM_033172
NM_033173
B3GALT5




UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5




chr1_-_209825673 1.309 NM_001127641
LAMB3
laminin, beta 3
chr7_-_99006215 1.308 PDAP1
PDGFA associated protein 1
chr11_-_88781039 1.304 NM_001143831
GRM5
glutamate receptor, metabotropic 5
chr18_+_21452981 1.301 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr6_-_30655078 1.301 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr9_+_35906188 1.298 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr5_-_39203061 1.296 FYB
FYN binding protein
chr12_+_105501556 1.295


chr10_+_13203547 1.293 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr9_+_4985243 1.293 NM_004972
JAK2
Janus kinase 2
chr8_+_26435339 1.292 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr1_+_230202966 1.290 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr19_+_35645640 1.287 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr8_+_26435466 1.287 DPYSL2
dihydropyrimidinase-like 2
chr17_-_37350051 1.286 CACNB1
calcium channel, voltage-dependent, beta 1 subunit
chrX_-_40594949 1.285 MED14
mediator complex subunit 14
chr11_+_57365026 1.280 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr7_+_106505876 1.280 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr4_-_139163222 1.270 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr11_+_61560352 1.269 FEN1
flap structure-specific endonuclease 1
chr2_+_113239733 1.266 NM_153712
TTL
tubulin tyrosine ligase
chr18_-_28681885 1.264 NM_004949
NM_024422
DSC2

desmocollin 2

chrX_+_17755562 1.263 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr2_-_31637553 1.259 XDH
xanthine dehydrogenase
chr17_+_39969200 1.250 FKBP10
FK506 binding protein 10, 65 kDa
chr2_-_192015751 1.249 STAT4
signal transducer and activator of transcription 4
chr1_-_21113758 1.243 HP1BP3
heterochromatin protein 1, binding protein 3
chr11_+_124933197 1.241 SLC37A2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr7_+_143078608 1.239 ZYX
zyxin
chr17_+_39969205 1.239 FKBP10
FK506 binding protein 10, 65 kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 1.65e-15 GO:0009987 cellular process
1.25 5.97e-13 GO:0007165 signal transduction
1.22 7.33e-12 GO:0023052 signaling
1.12 2.82e-10 GO:0065007 biological regulation
1.19 4.72e-10 GO:0051716 cellular response to stimulus
1.61 5.57e-09 GO:0007599 hemostasis
1.61 5.83e-09 GO:0007596 blood coagulation
1.61 5.83e-09 GO:0050817 coagulation
1.12 9.84e-09 GO:0050789 regulation of biological process
1.37 1.61e-08 GO:0002376 immune system process
1.55 1.63e-08 GO:0042060 wound healing
1.12 3.36e-08 GO:0050794 regulation of cellular process
1.40 6.17e-07 GO:0009611 response to wounding
1.13 7.15e-07 GO:0050896 response to stimulus
1.27 8.05e-07 GO:0007166 cell surface receptor linked signaling pathway
1.51 8.76e-07 GO:0050878 regulation of body fluid levels
1.21 1.08e-06 GO:0048518 positive regulation of biological process
1.65 1.04e-05 GO:0006412 translation
1.21 2.27e-05 GO:0048522 positive regulation of cellular process
1.17 5.09e-05 GO:0071840 cellular component organization or biogenesis
1.20 7.17e-05 GO:0006950 response to stress
1.17 9.48e-05 GO:0016043 cellular component organization
1.23 1.37e-04 GO:0010467 gene expression
1.76 1.79e-04 GO:0022411 cellular component disassembly
1.76 1.79e-04 GO:0071845 cellular component disassembly at cellular level
1.23 1.90e-04 GO:0048583 regulation of response to stimulus
1.46 2.90e-04 GO:0001775 cell activation
1.26 4.77e-04 GO:0035556 intracellular signal transduction
1.96 5.94e-04 GO:0032984 macromolecular complex disassembly
1.96 5.94e-04 GO:0034623 cellular macromolecular complex disassembly
1.81 6.15e-04 GO:0050900 leukocyte migration
1.13 9.67e-04 GO:0044260 cellular macromolecule metabolic process
1.99 1.35e-03 GO:0043241 protein complex disassembly
1.99 1.35e-03 GO:0043624 cellular protein complex disassembly
1.36 1.95e-03 GO:0002682 regulation of immune system process
1.39 2.15e-03 GO:0071822 protein complex subunit organization
1.29 2.75e-03 GO:0032879 regulation of localization
2.09 3.39e-03 GO:0002576 platelet degranulation
1.31 3.98e-03 GO:0040011 locomotion
1.15 4.01e-03 GO:0048856 anatomical structure development
1.16 5.94e-03 GO:0048731 system development
1.35 6.15e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.21 6.26e-03 GO:0034645 cellular macromolecule biosynthetic process
1.21 7.89e-03 GO:0009059 macromolecule biosynthetic process
1.28 8.61e-03 GO:0009605 response to external stimulus
1.98 9.15e-03 GO:0019080 viral genome expression
1.98 9.15e-03 GO:0019083 viral transcription
1.18 9.17e-03 GO:0065008 regulation of biological quality
1.96 9.74e-03 GO:0006415 translational termination
1.11 9.94e-03 GO:0043170 macromolecule metabolic process
1.13 1.13e-02 GO:0051179 localization
1.89 1.16e-02 GO:0006414 translational elongation
1.41 1.44e-02 GO:0002684 positive regulation of immune system process
1.57 1.47e-02 GO:0030168 platelet activation
1.15 1.64e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.31 1.69e-02 GO:0006955 immune response
1.13 1.70e-02 GO:0007275 multicellular organismal development
1.38 2.16e-02 GO:0034621 cellular macromolecular complex subunit organization
1.24 2.25e-02 GO:0044085 cellular component biogenesis
1.38 2.33e-02 GO:0006935 chemotaxis
1.38 2.33e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.38 2.33e-02 GO:0042330 taxis
1.23 2.83e-02 GO:0051641 cellular localization
1.49 3.12e-02 GO:0030029 actin filament-based process
1.28 3.70e-02 GO:0043933 macromolecular complex subunit organization
1.15 4.90e-02 GO:0071842 cellular component organization at cellular level
1.19 4.98e-02 GO:0016070 RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 6.78e-12 GO:0005829 cytosol
1.09 9.21e-07 GO:0005737 cytoplasm
1.12 1.98e-06 GO:0044444 cytoplasmic part
1.58 4.60e-05 GO:0015629 actin cytoskeleton
1.14 4.73e-04 GO:0032991 macromolecular complex
1.05 9.95e-04 GO:0005622 intracellular
1.05 1.42e-03 GO:0044424 intracellular part
2.17 2.65e-03 GO:0031091 platelet alpha granule
2.28 3.47e-03 GO:0031093 platelet alpha granule lumen
1.15 4.65e-03 GO:0043228 non-membrane-bounded organelle
1.15 4.65e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.61 5.39e-03 GO:0031252 cell leading edge
1.91 5.65e-03 GO:0030027 lamellipodium
2.23 5.82e-03 GO:0034774 secretory granule lumen
1.16 6.78e-03 GO:0044459 plasma membrane part
1.58 1.04e-02 GO:0005840 ribosome
2.14 1.53e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
1.89 2.74e-02 GO:0022626 cytosolic ribosome
1.32 3.50e-02 GO:0030529 ribonucleoprotein complex
2.06 3.69e-02 GO:0031983 vesicle lumen
1.40 4.34e-02 GO:0044433 cytoplasmic vesicle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 7.33e-24 GO:0005515 protein binding
1.08 2.09e-12 GO:0005488 binding
1.39 2.47e-04 GO:0005198 structural molecule activity
1.32 6.88e-04 GO:0003723 RNA binding
1.51 8.63e-04 GO:0003779 actin binding
1.68 9.27e-03 GO:0003735 structural constituent of ribosome
1.25 1.32e-02 GO:0005102 receptor binding
1.28 2.08e-02 GO:0042802 identical protein binding
1.33 2.09e-02 GO:0008092 cytoskeletal protein binding