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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SPZ1.p2

Z-value: 1.404

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_125133322	2.772		PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_76425207	2.492		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr1_-_20812271	2.300		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_+_37137882	2.283	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr20_+_33759773	2.227	NM_006404	PROCR	protein C receptor, endothelial
chr18_-_28681885	2.193	NM_004949 NM_024422	DSC2	desmocollin 2
chr4_+_75480628	2.190	NM_001657	AREG	amphiregulin
chr12_+_41086189	2.131	NM_001843 NM_175038	CNTN1	contactin 1
chr4_+_75310852	2.029	NM_001657	AREG	amphiregulin
chr3_-_197024879	2.009		DLG1	discs, large homolog 1 (Drosophila)
chr2_-_9143742	1.983	NM_138799	MBOAT2	membrane bound O-acyltransferase domain containing 2
chrX_-_46618596	1.880		SLC9A7	solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr2_-_208031570	1.846		KLF7	Kruppel-like factor 7 (ubiquitous)
chr2_+_30454396	1.817	NM_030915	LBH	limb bud and heart development homolog (mouse)
chr16_+_31483066	1.706	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr7_-_100860865	1.684		PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr22_+_31477231	1.670	NM_006932 NM_134269 NM_134270	SMTN	smoothelin
chr6_-_30654406	1.664		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr6_-_30654978	1.653		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr22_+_30792929	1.645	NM_001204204 NM_012429 NM_033382	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr9_+_125133228	1.626	NM_000962 NM_080591	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_30652434	1.612		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr15_-_75017710	1.592	NM_000499	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1
chr17_+_7905911	1.591	NM_000180	GUCY2D	guanylate cyclase 2D, membrane (retina-specific)
chr19_+_45281125	1.566	NM_001130852 NM_012116	CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c
chr9_+_131183225	1.561		CERCAM	cerebral endothelial cell adhesion molecule
chr2_+_33172368	1.548	NM_206943	LTBP1	latent transforming growth factor beta binding protein 1
chr6_+_34204928	1.493		HMGA1	high mobility group AT-hook 1
chr17_-_76921076	1.484		TIMP2	TIMP metallopeptidase inhibitor 2
chrX_-_46618471	1.451	NM_032591	SLC9A7	solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr7_-_100860719	1.443		PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr15_+_63340314	1.424	NM_001018008	TPM1	tropomyosin 1 (alpha)
chr1_+_15736387	1.369	NM_024329	EFHD2	EF-hand domain family, member D2
chr14_+_24867926	1.368	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr11_+_72929392	1.320	NM_176071	P2RY2	purinergic receptor P2Y, G-protein coupled, 2
chr17_-_39222126	1.319	NM_033184	KRTAP2-4	keratin associated protein 2-4
chr18_+_21269528	1.309	NM_001127717 NM_198129	LAMA3	laminin, alpha 3
chr17_+_73717596	1.276		ITGB4	integrin, beta 4
chr19_+_35645614	1.263	NM_014164	FXYD5	FXYD domain containing ion transport regulator 5
chr12_+_107712151	1.258	NM_001018072	BTBD11	BTB (POZ) domain containing 11
chr15_-_34629941	1.241	NM_001042494 NM_001042496	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr20_+_62328068	1.235		TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy
chr18_+_33877630	1.234	NM_025135	FHOD3	formin homology 2 domain containing 3
chr17_+_73717556	1.217		ITGB4	integrin, beta 4
chr19_+_35645640	1.215	NM_144779 NM_001164605	FXYD5	FXYD domain containing ion transport regulator 5
chr19_-_51143091	1.188	NM_001160328 NM_001160329	SYT3	synaptotagmin III
chr9_-_35115844	1.188	NM_025182	FAM214B	family with sequence similarity 214, member B
chr6_-_35109003	1.180	NM_001093728 NM_018679	TCP11	t-complex 11 homolog (mouse)
chr11_-_64646053	1.170	NM_006795	EHD1	EH-domain containing 1
chr1_+_16083132	1.169		FBLIM1	filamin binding LIM protein 1
chr1_+_150521786	1.167	NM_019032 NM_025008	ADAMTSL4	ADAMTS-like 4
chr9_+_140119643	1.148	NM_199001	C9orf169	chromosome 9 open reading frame 169
chr2_-_216300770	1.136	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr7_-_75623888	1.120		TMEM120A	transmembrane protein 120A
chr17_+_73717515	1.101	NM_000213 NM_001005731	ITGB4	integrin, beta 4
chr12_-_76425375	1.099	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr11_+_33061291	1.091		TCP11L1	t-complex 11 (mouse)-like 1
chr3_-_182833859	1.091		MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)
chr11_+_33061560	1.087	NM_001145541	TCP11L1	t-complex 11 (mouse)-like 1
chr21_-_44846927	1.076	NM_173354	SIK1	salt-inducible kinase 1
chr1_-_149908721	1.071		MTMR11	myotubularin related protein 11
chr6_+_42531951	1.062		UBR2	ubiquitin protein ligase E3 component n-recognin 2
chr14_-_60337350	1.061	NM_021136	RTN1	reticulon 1
chr1_-_50489489	1.060		AGBL4	ATP/GTP binding protein-like 4
chr19_+_49055421	1.051	NM_177973	SULT2B1	sulfotransferase family, cytosolic, 2B, member 1
chr18_+_21269404	1.048		LAMA3	laminin, alpha 3
chr11_-_64645925	1.046		EHD1	EH-domain containing 1
chr19_-_19051112	1.026	NM_001145722 NM_001145721	HOMER3	homer homolog 3 (Drosophila)
chr12_+_57522247	1.023	NM_002332	LRP1	low density lipoprotein receptor-related protein 1
chr12_+_113659287	1.020		TPCN1	two pore segment channel 1
chr12_-_49351263	1.019
chr17_-_80009237	1.017		RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_+_70117168	1.014		SOX9	SRY (sex determining region Y)-box 9
chr15_-_34630203	1.011	NM_001042495	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr8_+_22022677	1.009		BMP1	bone morphogenetic protein 1
chrX_+_56258785	1.004	NM_007250 NM_001159296	KLF8	Kruppel-like factor 8
chr8_-_144654921	1.003	NM_001100878	C8orf73	chromosome 8 open reading frame 73
chr2_-_165477986	0.998		GRB14	growth factor receptor-bound protein 14
chr17_+_70117154	0.998	NM_000346	SOX9	SRY (sex determining region Y)-box 9
chr7_-_100860841	0.995		PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr7_-_93519990	0.986	NM_006528	TFPI2	tissue factor pathway inhibitor 2
chr3_+_8543508	0.978	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr19_-_41933255	0.977
chr7_-_100860615	0.970		PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr6_-_13711643	0.963	NM_005493	RANBP9	RAN binding protein 9
chr3_-_119812512	0.960		GSK3B	glycogen synthase kinase 3 beta
chr5_+_148520985	0.959	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chr6_-_111894897	0.944	NM_001164282	TRAF3IP2	TRAF3 interacting protein 2
chr14_+_105173953	0.928		INF2	inverted formin, FH2 and WH2 domain containing
chr10_+_75910908	0.926	NM_001202450 NM_006721	ADK	adenosine kinase
chr17_+_70117177	0.923		SOX9	SRY (sex determining region Y)-box 9
chr19_+_54371150	0.923		MYADM	myeloid-associated differentiation marker
chr16_+_28834407	0.921	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr19_+_54385429	0.921	NM_002739	PRKCG	protein kinase C, gamma
chr7_-_100860991	0.914	NM_001084	PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_-_165477818	0.906		GRB14	growth factor receptor-bound protein 14
chrX_-_109561427	0.897		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr11_+_77300679	0.895	NM_173039	AQP11	aquaporin 11
chr8_-_125740378	0.893		MTSS1	metastasis suppressor 1
chr13_-_40177355	0.892	NM_005780	LHFP	lipoma HMGIC fusion partner
chr2_-_26205327	0.888		KIF3C	kinesin family member 3C
chr21_+_27107731	0.877		GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr16_+_28834372	0.876		ATXN2L	ataxin 2-like
chr16_+_58498182	0.875		NDRG4	NDRG family member 4
chr16_+_89696775	0.865		DPEP1	dipeptidase 1 (renal)
chr8_-_22089850	0.864	NM_001099335 NM_014759	PHYHIP	phytanoyl-CoA 2-hydroxylase interacting protein
chr17_+_45608443	0.854	NM_006310	NPEPPS	aminopeptidase puromycin sensitive
chr8_-_125740650	0.854	NM_014751	MTSS1	metastasis suppressor 1
chr22_-_30234253	0.847	NM_001242906 NM_032204	ASCC2	activating signal cointegrator 1 complex subunit 2
chr1_+_203595897	0.839	NM_001001396 NM_001684	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr7_+_143079925	0.838		ZYX	zyxin
chr19_-_41934634	0.837	NM_198540	B3GNT8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr16_+_28834360	0.823		ATXN2L	ataxin 2-like
chr6_+_74405933	0.821		CD109	CD109 molecule
chr12_+_120972155	0.817		RNF10	ring finger protein 10
chr6_+_74405909	0.809		CD109	CD109 molecule
chr12_-_72057676	0.808	NM_144982	ZFC3H1	zinc finger, C3H1-type containing
chr2_+_28616360	0.801		FOSL2	FOS-like antigen 2
chr6_-_109775423	0.800		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr9_-_95527002	0.800	NM_001003800 NM_015250	BICD2	bicaudal D homolog 2 (Drosophila)
chr20_+_1876006	0.799		SIRPA	signal-regulatory protein alpha
chr2_-_85637486	0.798	NM_001747	CAPG	capping protein (actin filament), gelsolin-like
chr2_+_28616346	0.798		FOSL2	FOS-like antigen 2
chr13_+_110959592	0.798	NM_001846	COL4A2	collagen, type IV, alpha 2
chr19_+_54371125	0.793	NM_001020819 NM_138373	MYADM	myeloid-associated differentiation marker
chr16_-_90085786	0.788	NM_001042610	DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1
chr9_+_131183122	0.785		CERCAM	cerebral endothelial cell adhesion molecule
chr7_-_45128492	0.780	NM_001146334	NACAD	NAC alpha domain containing
chr6_-_30655078	0.778	NM_001134870	PPP1R18	protein phosphatase 1, regulatory subunit 18
chr1_-_39325317	0.777	NM_022157	RRAGC	Ras-related GTP binding C
chr20_+_1875825	0.772	NM_001040023	SIRPA	signal-regulatory protein alpha
chr12_+_104850641	0.770	NM_001173982 NM_018413	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr1_+_955536	0.766
chr7_+_5632453	0.764		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr19_-_10679328	0.763		CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr7_-_25019625	0.762	NM_015550 NM_145320 NM_145321 NM_145322	OSBPL3	oxysterol binding protein-like 3
chr5_+_92920592	0.761		NR2F1 NR2F2	nuclear receptor subfamily 2, group F, member 1 nuclear receptor subfamily 2, group F, member 2
chr12_+_53440809	0.756	NM_198316	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_65991357	0.755	NM_001198687 NM_001198688 NM_001198689	LEPR	leptin receptor
chr4_+_99182520	0.754	NM_001100426 NM_001100427 NM_001100428 NM_001100429 NM_001100430 NM_021159	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1
chrX_+_49126326	0.751		PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr17_+_40610897	0.751		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_+_15736422	0.750		EFHD2	EF-hand domain family, member D2
chr2_-_228029274	0.743	NM_000092	COL4A4	collagen, type IV, alpha 4
chr11_-_2160199	0.741	NM_000612	IGF2	insulin-like growth factor 2 (somatomedin A)
chr7_+_40174594	0.740		C7orf10	chromosome 7 open reading frame 10
chr19_+_45349560	0.736		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr12_-_109915127	0.733	NM_031954	KCTD10	potassium channel tetramerisation domain containing 10
chr16_+_89696674	0.728		DPEP1	dipeptidase 1 (renal)
chr6_-_32160637	0.728		GPSM3	G-protein signaling modulator 3
chr8_-_23177481	0.727		LOXL2	lysyl oxidase-like 2
chr9_+_33240165	0.727	NM_014471	SPINK4	serine peptidase inhibitor, Kazal type 4
chr3_+_25469749	0.727	NM_016152	RARB	retinoic acid receptor, beta
chr2_-_85637473	0.726		CAPG	capping protein (actin filament), gelsolin-like
chr19_-_1174263	0.720	NM_014963	SBNO2	strawberry notch homolog 2 (Drosophila)
chr15_+_91411884	0.720	NM_002569	FURIN	furin (paired basic amino acid cleaving enzyme)
chr12_-_49351240	0.714		ARF3	ADP-ribosylation factor 3
chr20_+_361938	0.709		TRIB3	tribbles homolog 3 (Drosophila)
chr17_+_40610875	0.708		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr2_+_79740059	0.707	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chr4_+_142557722	0.704	NM_000585 NM_172175	IL15	interleukin 15
chr1_-_149908759	0.700	NM_001145862	MTMR11	myotubularin related protein 11
chr19_-_45909566	0.696	NM_001142502	PPP1R13L	protein phosphatase 1, regulatory subunit 13 like
chr1_+_109792640	0.693	NM_001408	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr9_-_107690526	0.692	NM_005502	ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr1_-_109825683	0.691		PSRC1	proline/serine-rich coiled-coil 1
chr5_+_95998678	0.691		CAST	calpastatin
chr2_+_23608297	0.688	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr2_+_201676597	0.687		BZW1	basic leucine zipper and W2 domains 1
chr7_+_143079354	0.685		ZYX	zyxin
chr17_-_36955676	0.684		PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr1_-_109825767	0.682	NM_001005290 NM_001032291 NM_032636	PSRC1	proline/serine-rich coiled-coil 1
chr17_+_37894161	0.680	NM_005310	GRB7	growth factor receptor-bound protein 7
chr1_+_152956563	0.679	NM_001199828 NM_005987	SPRR1A	small proline-rich protein 1A
chr6_-_11382501	0.678	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr18_-_57364643	0.675	NM_133459	CCBE1	collagen and calcium binding EGF domains 1
chr7_+_40174480	0.673	NM_001193311 NM_001193312 NM_001193313 NM_024728	C7orf10	chromosome 7 open reading frame 10
chrX_-_109561298	0.670		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr9_+_131102786	0.669	NM_005094	SLC27A4	solute carrier family 27 (fatty acid transporter), member 4
chr9_+_128509616	0.669	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr18_+_51795848	0.665	NM_007195	POLI	polymerase (DNA directed) iota
chrX_+_43515441	0.664		MAOA	monoamine oxidase A
chr5_+_150400132	0.662		GPX3	glutathione peroxidase 3 (plasma)
chr2_+_201676659	0.660		BZW1	basic leucine zipper and W2 domains 1
chr17_+_45286713	0.660	NM_002476	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr2_-_43019675	0.655	NM_012205	HAAO	3-hydroxyanthranilate 3,4-dioxygenase
chr2_-_26205437	0.653	NM_002254	KIF3C	kinesin family member 3C
chr17_-_73840422	0.645		UNC13D	unc-13 homolog D (C. elegans)
chr1_+_203595929	0.645		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr19_+_46195740	0.642	NM_001163377 NM_017659	QPCTL	glutaminyl-peptide cyclotransferase-like
chr2_-_165478357	0.640	NM_004490	GRB14	growth factor receptor-bound protein 14
chr17_-_40333190	0.639	NM_012285	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_+_5617330	0.638	NM_058166	TRIM6	tripartite motif containing 6
chr5_+_87564729	0.636		LOC100505894	uncharacterized LOC100505894
chr19_+_925984	0.635	NM_005224	ARID3A	AT rich interactive domain 3A (BRIGHT-like)
chr1_-_153521717	0.635	NM_002960	S100A3	S100 calcium binding protein A3
chr17_-_41856180	0.632	NM_004090	DUSP3	dual specificity phosphatase 3
chr17_-_34122547	0.632	NM_001032278 NM_024302	MMP28	matrix metallopeptidase 28
chr1_+_153651050	0.630	NM_000906	NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr8_-_25315941	0.629	NM_017634	KCTD9	potassium channel tetramerisation domain containing 9

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.30	7.59e-20	GO:0023052	signaling
1.30	1.64e-17	GO:0007165	signal transduction
1.15	3.87e-15	GO:0065007	biological regulation
1.17	1.15e-14	GO:0050794	regulation of cellular process
1.15	2.00e-13	GO:0050789	regulation of biological process
1.09	1.45e-12	GO:0009987	cellular process
1.22	6.91e-12	GO:0051716	cellular response to stimulus
1.49	1.26e-09	GO:0022008	neurogenesis
1.29	1.30e-09	GO:0048519	negative regulation of biological process
1.26	4.62e-09	GO:0048518	positive regulation of biological process
1.49	1.06e-08	GO:0048699	generation of neurons
1.65	1.33e-08	GO:0000904	cell morphogenesis involved in differentiation
1.28	3.21e-08	GO:0048523	negative regulation of cellular process
1.64	4.27e-08	GO:0031175	neuron projection development
1.31	5.02e-08	GO:0007166	cell surface receptor linked signaling pathway
1.67	5.14e-08	GO:0048812	neuron projection morphogenesis
1.58	6.22e-08	GO:0048666	neuron development
1.26	6.26e-08	GO:0048522	positive regulation of cellular process
1.66	1.11e-07	GO:0048667	cell morphogenesis involved in neuron differentiation
1.14	1.36e-07	GO:0050896	response to stimulus
1.32	1.46e-07	GO:0023051	regulation of signaling
1.34	2.20e-07	GO:0009653	anatomical structure morphogenesis
1.34	3.69e-07	GO:0009966	regulation of signal transduction
1.29	8.10e-07	GO:0048583	regulation of response to stimulus
1.49	8.57e-07	GO:0030182	neuron differentiation
1.26	9.03e-07	GO:0065008	regulation of biological quality
1.64	1.06e-06	GO:0007409	axonogenesis
1.42	1.42e-06	GO:0048468	cell development
1.34	1.43e-06	GO:0035556	intracellular signal transduction
1.51	1.78e-06	GO:0030030	cell projection organization
1.87	2.08e-06	GO:0048011	nerve growth factor receptor signaling pathway
1.71	2.26e-06	GO:0007411	axon guidance
1.56	2.94e-06	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.31	3.81e-06	GO:0007399	nervous system development
1.49	5.43e-06	GO:0007167	enzyme linked receptor protein signaling pathway
1.50	1.18e-05	GO:0000902	cell morphogenesis
1.48	1.70e-05	GO:0032989	cellular component morphogenesis
2.01	2.37e-05	GO:0034330	cell junction organization
1.43	2.99e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.48	3.62e-05	GO:0042060	wound healing
1.53	3.72e-05	GO:0048858	cell projection morphogenesis
1.17	4.60e-05	GO:0032502	developmental process
1.24	4.76e-05	GO:0030154	cell differentiation
1.51	7.09e-05	GO:0032990	cell part morphogenesis
1.53	9.35e-05	GO:0045859	regulation of protein kinase activity
1.34	9.64e-05	GO:0010646	regulation of cell communication
1.39	1.01e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.48	1.13e-04	GO:0050878	regulation of body fluid levels
1.38	1.16e-04	GO:0009891	positive regulation of biosynthetic process
1.23	1.78e-04	GO:0048869	cellular developmental process
1.22	2.08e-04	GO:0042221	response to chemical stimulus
1.43	2.09e-04	GO:0010628	positive regulation of gene expression
1.50	2.74e-04	GO:0043549	regulation of kinase activity
1.41	2.87e-04	GO:0019220	regulation of phosphate metabolic process
1.41	2.87e-04	GO:0051174	regulation of phosphorus metabolic process
1.44	3.29e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.42	3.48e-04	GO:0042325	regulation of phosphorylation
1.37	4.51e-04	GO:0051128	regulation of cellular component organization
1.34	4.52e-04	GO:0032879	regulation of localization
1.17	4.77e-04	GO:0048856	anatomical structure development
1.16	5.09e-04	GO:0007275	multicellular organismal development
1.29	5.56e-04	GO:0051239	regulation of multicellular organismal process
1.63	6.49e-04	GO:0030029	actin filament-based process
1.48	6.79e-04	GO:0007599	hemostasis
1.54	6.80e-04	GO:0007264	small GTPase mediated signal transduction
1.38	6.91e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.41	7.22e-04	GO:0051254	positive regulation of RNA metabolic process
1.38	7.50e-04	GO:2000026	regulation of multicellular organismal development
1.48	7.64e-04	GO:0007596	blood coagulation
1.48	7.64e-04	GO:0050817	coagulation
1.30	8.29e-04	GO:0031325	positive regulation of cellular metabolic process
1.29	9.42e-04	GO:0009893	positive regulation of metabolic process
1.38	9.54e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.94	9.69e-04	GO:0034329	cell junction assembly
1.18	9.70e-04	GO:0048731	system development
1.35	1.00e-03	GO:0040011	locomotion
1.41	1.23e-03	GO:0001932	regulation of protein phosphorylation
1.46	1.66e-03	GO:0051338	regulation of transferase activity
1.32	1.78e-03	GO:0042127	regulation of cell proliferation
1.29	2.29e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.16	2.34e-03	GO:0016043	cellular component organization
1.15	2.46e-03	GO:0051179	localization
1.33	2.54e-03	GO:0050793	regulation of developmental process
1.96	2.59e-03	GO:0007265	Ras protein signal transduction
1.45	3.13e-03	GO:0048585	negative regulation of response to stimulus
1.30	3.99e-03	GO:0032268	regulation of cellular protein metabolic process
1.29	6.19e-03	GO:0051246	regulation of protein metabolic process
1.58	6.50e-03	GO:0071900	regulation of protein serine/threonine kinase activity
1.30	6.98e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.30	7.95e-03	GO:0006793	phosphorus metabolic process
1.30	7.95e-03	GO:0006796	phosphate metabolic process
1.61	9.00e-03	GO:0030036	actin cytoskeleton organization
1.42	9.35e-03	GO:0006935	chemotaxis
1.42	9.35e-03	GO:0042330	taxis
1.11	9.81e-03	GO:0032501	multicellular organismal process
1.55	1.03e-02	GO:0022603	regulation of anatomical structure morphogenesis
1.69	1.24e-02	GO:0048732	gland development
1.14	1.34e-02	GO:0071840	cellular component organization or biogenesis
1.47	1.49e-02	GO:0009968	negative regulation of signal transduction
1.42	1.64e-02	GO:0019226	transmission of nerve impulse
1.42	1.64e-02	GO:0035637	multicellular organismal signaling
1.32	1.79e-02	GO:0031399	regulation of protein modification process
1.46	1.80e-02	GO:0007243	intracellular protein kinase cascade
1.46	1.80e-02	GO:0023014	signal transduction via phosphorylation event
1.44	2.00e-02	GO:0046903	secretion
1.53	2.16e-02	GO:0045860	positive regulation of protein kinase activity
1.52	2.45e-02	GO:0060284	regulation of cell development
1.61	2.69e-02	GO:0051129	negative regulation of cellular component organization
1.33	2.84e-02	GO:0006468	protein phosphorylation
2.49	2.85e-02	GO:0048145	regulation of fibroblast proliferation
1.54	2.95e-02	GO:0051270	regulation of cellular component movement
1.38	3.09e-02	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.51	3.24e-02	GO:0033674	positive regulation of kinase activity
1.40	3.90e-02	GO:0007010	cytoskeleton organization
1.13	4.31e-02	GO:0031323	regulation of cellular metabolic process
1.39	4.65e-02	GO:0008284	positive regulation of cell proliferation
1.27	4.92e-02	GO:0007154	cell communication

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	8.88e-15	GO:0005737	cytoplasm
1.27	4.37e-08	GO:0005829	cytosol
1.06	3.72e-06	GO:0005622	intracellular
1.12	3.86e-06	GO:0044444	cytoplasmic part
1.06	4.75e-06	GO:0044424	intracellular part
1.22	1.81e-05	GO:0044459	plasma membrane part
1.44	3.17e-05	GO:0030054	cell junction
1.15	3.19e-05	GO:0071944	cell periphery
1.14	2.78e-04	GO:0005886	plasma membrane
1.24	2.95e-04	GO:0005856	cytoskeleton
1.58	4.70e-04	GO:0015629	actin cytoskeleton
1.49	4.71e-04	GO:0043005	neuron projection
1.77	4.74e-04	GO:0070161	anchoring junction
1.81	6.14e-04	GO:0005912	adherens junction
1.03	6.89e-04	GO:0044464	cell part
1.03	7.29e-04	GO:0005623	cell
1.84	1.10e-03	GO:0005938	cell cortex
1.32	1.61e-03	GO:0031982	vesicle
1.33	1.65e-03	GO:0031410	cytoplasmic vesicle
1.30	2.88e-03	GO:0042995	cell projection
1.32	4.33e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
2.82	4.92e-03	GO:0001725	stress fiber
1.77	5.70e-03	GO:0043235	receptor complex
1.88	6.32e-03	GO:0005924	cell-substrate adherens junction
1.31	7.02e-03	GO:0031988	membrane-bounded vesicle
1.88	1.00e-02	GO:0005925	focal adhesion
1.63	1.06e-02	GO:0031252	cell leading edge
2.63	1.75e-02	GO:0032432	actin filament bundle
1.81	1.87e-02	GO:0030055	cell-substrate junction
2.53	2.06e-02	GO:0042641	actomyosin
1.58	4.76e-02	GO:0030424	axon

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.20	1.14e-24	GO:0005515	protein binding
1.07	6.58e-10	GO:0005488	binding
1.57	5.93e-08	GO:0008092	cytoskeletal protein binding
1.43	3.29e-06	GO:0019899	enzyme binding
1.55	7.01e-04	GO:0003779	actin binding
1.34	1.23e-03	GO:0016301	kinase activity
1.35	1.39e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.37	4.05e-03	GO:0004672	protein kinase activity
1.17	5.68e-03	GO:0000166	nucleotide binding
1.27	2.37e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.25	3.20e-02	GO:0005102	receptor binding
1.18	3.21e-02	GO:0032553	ribonucleotide binding
1.18	3.21e-02	GO:0032555	purine ribonucleotide binding
1.49	4.45e-02	GO:0032403	protein complex binding
1.17	4.46e-02	GO:0017076	purine nucleotide binding
2.09	4.85e-02	GO:0035591	signaling adaptor activity