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Motif ID: SRF.p3

Z-value: 2.198

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_137801166	21.770		EGR1	early growth response 1
chr5_+_137801178	14.083	NM_001964	EGR1	early growth response 1
chr11_-_65667858	12.953		FOSL1	FOS-like antigen 1
chr22_+_31480981	12.344	NM_001207018	SMTN	smoothelin
chr6_+_151561094	12.175	NM_005100	AKAP12	A kinase (PRKA) anchor protein 12
chr14_-_94443065	10.295	NM_001202429	ASB2	ankyrin repeat and SOCS box containing 2
chr11_-_65667860	9.390	NM_005438	FOSL1	FOS-like antigen 1
chr2_+_74120132	9.374		ACTG2	actin, gamma 2, smooth muscle, enteric
chr2_+_74120092	9.331	NM_001199893 NM_001615	ACTG2	actin, gamma 2, smooth muscle, enteric
chr2_-_161056762	8.831		ITGB6	integrin, beta 6
chr11_-_65667809	8.594		FOSL1	FOS-like antigen 1
chr14_-_94442894	7.681		ASB2	ankyrin repeat and SOCS box containing 2
chr19_+_16178170	6.821	NM_001145160	TPM4	tropomyosin 4
chr10_+_112257624	6.767	NM_004419	DUSP5	dual specificity phosphatase 5
chr2_-_161056573	6.174	NM_000888	ITGB6	integrin, beta 6
chr12_+_75874512	5.935	NM_006851	GLIPR1	GLI pathogenesis-related 1
chrX_-_153602928	5.475		FLNA	filamin A, alpha
chr19_+_54372659	5.156	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr1_-_168106810	5.051		GPR161	G protein-coupled receptor 161
chr3_-_123339423	4.821	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr6_+_151561508	4.697		AKAP12	A kinase (PRKA) anchor protein 12
chr1_-_168106727	4.616		GPR161	G protein-coupled receptor 161
chr1_-_153433104	4.535	NM_002963	S100A7	S100 calcium binding protein A7
chr1_-_168106535	4.514		GPR161	G protein-coupled receptor 161
chr9_+_116356199	4.396	NM_144489	RGS3	regulator of G-protein signaling 3
chr14_+_75745480	4.395	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr1_+_167599329	4.287	NM_052862	RCSD1	RCSD domain containing 1
chr10_-_29923900	4.269	NM_021738	SVIL	supervillin
chr10_-_90712510	4.259	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr20_+_35169876	4.143	NM_006097 NM_181526	MYL9	myosin, light chain 9, regulatory
chr7_-_107643330	4.141	NM_002291	LAMB1	laminin, beta 1
chr3_-_123339178	4.062		MYLK	myosin light chain kinase
chr14_-_53417808	3.939	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chrX_-_153602998	3.841	NM_001110556 NM_001456	FLNA	filamin A, alpha
chr20_+_35169897	3.744		MYL9	myosin, light chain 9, regulatory
chr6_-_88411948	3.724		AKIRIN2	akirin 2
chr1_-_229569839	3.697	NM_001100	ACTA1	actin, alpha 1, skeletal muscle
chr15_+_45406518	3.609	NM_207581	DUOXA2	dual oxidase maturation factor 2
chr19_-_15343767	3.573	NM_001142886	EPHX3	epoxide hydrolase 3
chr4_+_87928083	3.490	NM_005935	AFF1	AF4/FMR2 family, member 1
chr6_-_109775423	3.306		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr7_+_143078399	3.303		ZYX	zyxin
chr1_+_16085245	3.273	NM_017556	FBLIM1	filamin binding LIM protein 1
chr7_+_143078358	3.248	NM_001010972 NM_003461	ZYX	zyxin
chr19_+_17666457	3.220		GLT25D1	glycosyltransferase 25 domain containing 1
chr5_+_92918924	3.155	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr7_+_134464161	3.010	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr12_-_11548485	2.964	NM_006248	PRB1 PRB2	proline-rich protein BstNI subfamily 1 proline-rich protein BstNI subfamily 2
chr1_+_153388999	2.863	NM_176823	S100A7A	S100 calcium binding protein A7A
chr3_-_99594915	2.800	NM_014890	FILIP1L	filamin A interacting protein 1-like
chr7_+_143078395	2.775		ZYX	zyxin
chr7_+_143078444	2.748		ZYX	zyxin
chr19_+_1026608	2.733		CNN2	calponin 2
chr7_+_143078447	2.704		ZYX	zyxin
chr15_-_70390226	2.679		TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr19_+_45971249	2.659	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr12_-_50616425	2.530	NM_001113547	LIMA1	LIM domain and actin binding 1
chr1_+_11994710	2.506	NM_000302	PLOD1	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr17_-_72357957	2.395	NM_001080466	BTBD17	BTB (POZ) domain containing 17
chr12_+_4382882	2.389	NM_001759	CCND2	cyclin D2
chr7_+_143078457	2.371		ZYX	zyxin
chr6_-_88411649	2.286		AKIRIN2	akirin 2
chr17_-_4890664	2.261	NM_001171167 NM_001171168	CAMTA2	calmodulin binding transcription activator 2
chr15_+_33603162	2.251	NM_001036 NM_001243996	RYR3	ryanodine receptor 3
chr6_-_88411872	2.248		AKIRIN2	akirin 2
chr15_-_59665069	2.241	NM_004998	MYO1E	myosin IE
chr12_-_91505541	2.229	NM_002345	LUM	lumican
chr12_-_11508509	2.209	NM_005039 NM_199353 NM_199354	PRB1	proline-rich protein BstNI subfamily 1
chr6_-_117150197	2.158	NM_148963	GPRC6A	G protein-coupled receptor, family C, group 6, member A
chr2_+_219283809	2.153	NM_007127	VIL1	villin 1
chr19_+_45417576	2.148		APOC1	apolipoprotein C-I
chr11_+_66314373	2.048	NM_001104	ACTN3	actinin, alpha 3
chrX_-_153599719	2.012		FLNA	filamin A, alpha
chr17_-_4890920	2.012	NM_001171166 NM_015099	CAMTA2	calmodulin binding transcription activator 2
chr16_-_11375094	1.968	NM_002761	PRM1	protamine 1
chr10_-_16859389	1.934		RSU1	Ras suppressor protein 1
chr22_-_36784055	1.871	NM_002473	MYH9	myosin, heavy chain 9, non-muscle
chr19_+_16187306	1.766		TPM4	tropomyosin 4
chr2_+_87754991	1.761		LINC00152	long intergenic non-protein coding RNA 152
chr4_-_10118460	1.749		WDR1	WD repeat domain 1
chr10_-_16859336	1.695		RSU1	Ras suppressor protein 1
chr7_+_143078608	1.691		ZYX	zyxin
chr11_-_123065836	1.656		CLMP	CXADR-like membrane protein
chr9_+_116356407	1.650		RGS3	regulator of G-protein signaling 3
chr1_+_50574601	1.611		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_+_26348488	1.588	NM_005086	SSPN	sarcospan (Kras oncogene-associated gene)
chr2_-_208031570	1.572		KLF7	Kruppel-like factor 7 (ubiquitous)
chr4_-_10118444	1.536		WDR1	WD repeat domain 1
chr11_+_62432778	1.529	NM_001043229	METTL12	methyltransferase like 12
chr17_-_41132019	1.528	NM_025267	AARSD1	alanyl-tRNA synthetase domain containing 1
chr5_-_179050635	1.491		HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr19_+_1026627	1.475		CNN2	calponin 2
chr20_-_656443	1.457
chr2_-_172087823	1.452	NM_001136554	TLK1	tousled-like kinase 1
chr7_-_27183225	1.439	NM_019102	HOXA5	homeobox A5
chr10_+_75757847	1.438	NM_003373 NM_014000	VCL	vinculin
chr11_+_117070039	1.429	NM_001001522 NM_003186	TAGLN	transgelin
chr18_-_44544606	1.407	NM_001242907	LOC100506888	transcription elongation factor B polypeptide 3C-like
chr4_+_156680125	1.389	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr21_-_28217272	1.369		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr13_-_46742678	1.352		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_11994778	1.345		PLOD1	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr2_-_106015423	1.313	NM_001039492 NM_001450 NM_201555	FHL2	four and a half LIM domains 2
chr17_+_39868577	1.310	NM_000805	GAST	gastrin
chr16_+_31483066	1.303	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr11_+_66188474	1.290	NM_178864	NPAS4	neuronal PAS domain protein 4
chr19_+_16187047	1.244	NM_003290	TPM4	tropomyosin 4
chr1_-_242162364	1.167	NM_001004343	MAP1LC3C	microtubule-associated protein 1 light chain 3 gamma
chr5_-_33892292	1.158		ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr7_-_559479	1.145	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr15_-_59665053	1.145		MYO1E	myosin IE
chr17_-_37350051	1.144		CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr9_+_139249251	1.132	NM_001200003	GPSM1	G-protein signaling modulator 1
chr2_+_108602978	1.125	NM_021815	SLC5A7	solute carrier family 5 (choline transporter), member 7
chr18_-_44556448	1.107	NM_145653	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)
chr5_-_179050675	1.080	NM_005520	HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr1_-_111174095	1.053	NM_001204269	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2
chr4_+_155665150	1.047	NM_004744	LRAT	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr3_-_46904879	1.043	NM_000258	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr18_-_44550533	1.042	NM_001242907 NM_145653	LOC100506888 TCEB3C	transcription elongation factor B polypeptide 3C-like transcription elongation factor B polypeptide 3C (elongin A3)
chr6_+_43139201	1.031		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr18_-_44556208	0.997	NM_001100817	TCEB3C TCEB3CL	transcription elongation factor B polypeptide 3C (elongin A3) transcription elongation factor B polypeptide 3C-like
chr5_-_142000899	0.979	NM_001144892	FGF1	fibroblast growth factor 1 (acidic)
chr4_+_6695565	0.979	NM_005980	S100P	S100 calcium binding protein P
chr14_-_74226890	0.977	NM_194278	C14orf43	chromosome 14 open reading frame 43
chr6_+_167525294	0.952	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr5_-_33891967	0.950	NM_030955	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr10_-_98119058	0.937	NM_001040102 NM_001040103 NM_033207	OPALIN	oligodendrocytic myelin paranodal and inner loop protein
chr15_-_35087748	0.937	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr19_-_47975244	0.908	NM_015063	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chrX_-_37706816	0.906	NM_006520	DYNLT3	dynein, light chain, Tctex-type 3
chr6_+_158402928	0.862		SYNJ2	synaptojanin 2
chr1_-_11907741	0.859	NM_006172	NPPA	natriuretic peptide A
chr9_+_140772228	0.854	NM_000718 NM_001243812	CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr7_+_93551015	0.852	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr7_+_112120907	0.851	NM_001134468 NM_182597	C7orf53	chromosome 7 open reading frame 53
chr7_-_44180911	0.833	NM_021223	MYL7	myosin, light chain 7, regulatory
chr12_-_11463353	0.832	NM_002723	PRB4	proline-rich protein BstNI subfamily 4
chr16_+_68877492	0.823	NM_024562	TMCO7	transmembrane and coiled-coil domains 7
chr6_-_123957941	0.804	NM_001251987 NM_006073	TRDN	triadin
chr8_-_22550708	0.800	NM_004430	EGR3	early growth response 3
chr1_-_154164551	0.767	NM_152263	TPM3	tropomyosin 3
chr17_+_33914320	0.760		AP2B1	adaptor-related protein complex 2, beta 1 subunit
chr2_+_87755059	0.753		LINC00152	long intergenic non-protein coding RNA 152
chr12_-_8765438	0.753	NM_020661	AICDA	activation-induced cytidine deaminase
chr2_+_139259476	0.749
chr12_+_62654120	0.742	NM_001252078 NM_001252079 NM_006313	USP15	ubiquitin specific peptidase 15
chr2_+_26915390	0.737	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr7_-_5570188	0.722	NM_001101	ACTB	actin, beta
chr6_-_105584982	0.713	NM_001199563	BVES	blood vessel epicardial substance
chr1_+_181057835	0.710		IER5	immediate early response 5
chr19_+_42082530	0.687	NM_001098506 NM_033543	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21
chr3_-_101405400	0.667	NM_000986	RPL24	ribosomal protein L24
chr16_+_70657894	0.653	NM_001172772	IL34	interleukin 34
chr2_-_96811138	0.650	NM_004418	DUSP2	dual specificity phosphatase 2
chr1_-_150552077	0.649		MCL1	myeloid cell leukemia sequence 1 (BCL2-related)
chr4_+_24797084	0.647	NM_003102	SOD3	superoxide dismutase 3, extracellular
chr15_-_45406345	0.646	NM_014080	DUOX2	dual oxidase 2
chr15_+_40674921	0.643	NM_001142761 NM_001142762 NM_033286	C15orf23	chromosome 15 open reading frame 23
chrX_-_152939256	0.640		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr11_+_63580922	0.639	NM_138471	C11orf84	chromosome 11 open reading frame 84
chr18_+_61144143	0.632	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr15_+_40675187	0.619		C15orf23	chromosome 15 open reading frame 23
chr15_-_65360297	0.615	NM_016563	RASL12	RAS-like, family 12
chr2_-_231989755	0.611	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr16_-_67977956	0.602	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr6_-_88411984	0.595	NM_018064	AKIRIN2	akirin 2
chr19_+_45417920	0.590	NM_001645	APOC1	apolipoprotein C-I
chr6_+_158402916	0.589		SYNJ2	synaptojanin 2
chr4_-_10118500	0.587	NM_005112 NM_017491	WDR1	WD repeat domain 1
chr16_+_30077120	0.586		ALDOA	aldolase A, fructose-bisphosphate
chr20_-_42815732	0.582		JPH2	junctophilin 2
chr9_-_19102906	0.577		HAUS6	HAUS augmin-like complex, subunit 6
chr6_+_158402887	0.566	NM_003898	SYNJ2	synaptojanin 2
chr8_-_101965096	0.553		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr17_+_3379295	0.545	NM_000049	ASPA	aspartoacylase
chr7_+_115863004	0.539	NM_152829	TES	testis derived transcript (3 LIM domains)
chr11_-_75921785	0.537		WNT11	wingless-type MMTV integration site family, member 11
chrX_-_103499559	0.527	NM_153448	ESX1	ESX homeobox 1
chr7_-_94285426	0.526		SGCE	sarcoglycan, epsilon
chr18_-_47806361	0.521	NM_001204151	MBD1	methyl-CpG binding domain protein 1
chr7_-_94285477	0.518	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr20_-_33872505	0.514	NM_181468	EIF6	eukaryotic translation initiation factor 6
chr8_-_101965601	0.508	NM_003406	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr17_-_1389013	0.505	NM_001080950	MYO1C	myosin IC
chrX_+_99839789	0.498	NM_022144	TNMD	tenomodulin
chr11_+_18416111	0.491		LDHA	lactate dehydrogenase A
chr7_-_94285372	0.491		SGCE	sarcoglycan, epsilon
chr13_-_78549663	0.483	NM_000115	EDNRB	endothelin receptor type B
chr7_-_121944485	0.477	NM_001024613 NM_001160264	FEZF1	FEZ family zinc finger 1
chr17_+_32612686	0.472	NM_002986	CCL11	chemokine (C-C motif) ligand 11
chr16_+_30077146	0.468		ALDOA	aldolase A, fructose-bisphosphate
chr11_-_16430425	0.459	NM_001145811	SOX6	SRY (sex determining region Y)-box 6
chr10_+_114043413	0.456	NM_058222	TECTB	tectorin beta
chr11_+_18416106	0.450		LDHA	lactate dehydrogenase A
chr6_+_43139190	0.446		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr18_-_44544366	0.445	NM_001100817	TCEB3C TCEB3CL	transcription elongation factor B polypeptide 3C (elongin A3) transcription elongation factor B polypeptide 3C-like
chr10_+_106034886	0.439	NM_001191014 NM_001191015	GSTO2	glutathione S-transferase omega 2
chr10_+_6186758	0.438	NM_001145443	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr18_-_65182507	0.437		DSEL	dermatan sulfate epimerase-like

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
9.94	1.19e-15	GO:0003012	muscle system process
10.40	1.83e-15	GO:0006936	muscle contraction
1.77	3.31e-10	GO:0032501	multicellular organismal process
16.75	5.82e-10	GO:0030048	actin filament-based movement
5.84	4.51e-09	GO:0030029	actin filament-based process
17.30	2.13e-07	GO:0070252	actin-mediated cell contraction
15.99	3.81e-06	GO:0030049	muscle filament sliding
15.99	3.81e-06	GO:0033275	actin-myosin filament sliding
1.76	9.28e-06	GO:0032502	developmental process
1.81	1.14e-05	GO:0007275	multicellular organismal development
1.84	2.51e-05	GO:0048856	anatomical structure development
2.17	1.17e-04	GO:0003008	system process
5.36	1.73e-04	GO:0007517	muscle organ development
8.65	2.58e-04	GO:0007015	actin filament organization
1.81	3.86e-04	GO:0048731	system development
4.32	5.77e-04	GO:0061061	muscle structure development
4.52	6.90e-04	GO:0030036	actin cytoskeleton organization
3.24	1.70e-03	GO:0007010	cytoskeleton organization
1.98	1.80e-03	GO:0048513	organ development
4.06	2.78e-03	GO:0010035	response to inorganic substance
6.38	4.45e-03	GO:0032970	regulation of actin filament-based process
1.81	8.42e-03	GO:0042221	response to chemical stimulus
1.21	9.94e-03	GO:0009987	cellular process
4.82	2.21e-02	GO:0040017	positive regulation of locomotion
2.22	2.49e-02	GO:0022607	cellular component assembly
5.92	2.52e-02	GO:0032956	regulation of actin cytoskeleton organization
1.30	4.04e-02	GO:0065007	biological regulation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
7.36	2.12e-16	GO:0015629	actin cytoskeleton
9.62	1.08e-10	GO:0043292	contractile fiber
9.89	3.07e-10	GO:0044449	contractile fiber part
9.63	4.77e-10	GO:0030016	myofibril
21.91	3.05e-09	GO:0032432	actin filament bundle
19.92	9.02e-09	GO:0042641	actomyosin
2.52	3.07e-08	GO:0005856	cytoskeleton
21.12	4.82e-08	GO:0001725	stress fiber
8.72	7.04e-07	GO:0030017	sarcomere
7.30	7.50e-05	GO:0005925	focal adhesion
2.44	1.12e-04	GO:0044430	cytoskeletal part
9.24	1.19e-04	GO:0016459	myosin complex
6.95	1.24e-04	GO:0005924	cell-substrate adherens junction
6.70	1.82e-04	GO:0030055	cell-substrate junction
1.76	3.23e-04	GO:0043228	non-membrane-bounded organelle
1.76	3.23e-04	GO:0043232	intracellular non-membrane-bounded organelle
5.30	7.10e-04	GO:0005912	adherens junction
4.78	2.04e-03	GO:0070161	anchoring junction
11.60	2.58e-03	GO:0005884	actin filament
20.22	7.83e-03	GO:0005865	striated muscle thin filament
20.22	7.83e-03	GO:0031672	A band
1.76	1.02e-02	GO:0005576	extracellular region
8.22	1.97e-02	GO:0031674	I band
1.68	2.88e-02	GO:0044459	plasma membrane part
14.61	3.15e-02	GO:0005859	muscle myosin complex
6.06	3.65e-02	GO:0033267	axon part
2.44	3.96e-02	GO:0030054	cell junction
13.15	4.88e-02	GO:0016460	myosin II complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
4.82	1.36e-07	GO:0003779	actin binding
13.76	3.44e-06	GO:0008307	structural constituent of muscle
3.45	6.05e-06	GO:0008092	cytoskeletal protein binding
2.74	2.15e-03	GO:0005198	structural molecule activity
8.85	3.25e-03	GO:0051015	actin filament binding
1.32	4.76e-03	GO:0005515	protein binding
13.15	8.08e-03	GO:0017022	myosin binding
4.73	1.34e-02	GO:0005516	calmodulin binding
16.43	2.05e-02	GO:0000146	microfilament motor activity