Motif ID: SRY.p2

Z-value: 1.339


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SRYchrY_-_2655478-0.441.6e-02Click!


Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_151488214 9.714 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr19_+_13134782 9.015 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr5_+_94727047 8.633 NM_152548
FAM81B
family with sequence similarity 81, member B
chr13_-_39564857 8.522 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr8_-_110655418 8.397 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr5_+_121465214 7.918 NM_207317
ZNF474
zinc finger protein 474
chr20_+_9288446 7.293 NM_000933
PLCB4
phospholipase C, beta 4
chr20_+_9198036 6.842 NM_182797
PLCB4
phospholipase C, beta 4
chr5_+_140247767 6.631 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr11_+_36317724 6.533 NM_001160167
PRR5L
proline rich 5 like
chr5_-_149792370 6.454 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr4_-_70518964 6.238 NM_001252274
NM_001252275
NM_006798
UGT2A1


UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus


chr3_+_171561138 6.053 NM_001164436
TMEM212
transmembrane protein 212
chr6_-_32557431 6.038 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr3_+_63638343 6.012 NM_001080537
SNTN
sentan, cilia apical structure protein
chr4_+_36285643 5.658 NM_001170700
DTHD1
death domain containing 1
chr4_+_81256873 5.329 NM_001206997
NM_152770
C4orf22

chromosome 4 open reading frame 22

chr6_-_52668599 5.247 NM_145740
GSTA1
glutathione S-transferase alpha 1
chr6_-_76203256 5.085 NM_015687
FILIP1
filamin A interacting protein 1
chr1_-_161337663 5.073 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr7_-_16921596 4.794 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr6_-_32497925 4.759 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr10_+_115511212 4.745 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81


chr7_+_142829169 4.735 NM_002652
PIP
prolactin-induced protein
chr13_+_36050885 4.381 NM_001204197
NBEA
neurobeachin
chr11_+_6897855 4.380 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr4_-_38806410 4.372 NM_003263
TLR1
toll-like receptor 1
chr13_+_50589389 4.336 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr4_-_100356449 4.230 NM_000673
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr16_-_52581713 4.213 NM_001146188
TOX3
TOX high mobility group box family member 3
chr1_+_104292439 4.210 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr11_+_73359734 4.167 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr18_-_45663667 4.164 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr16_-_21314371 4.144 NM_001014444
NM_001888
CRYM

crystallin, mu

chr6_-_29527477 4.131 UBD
ubiquitin D
chr14_-_89883306 3.988 NM_005197
FOXN3
forkhead box N3
chr6_-_29527701 3.933 NM_006398
UBD
ubiquitin D
chr6_-_32920812 3.818 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr20_-_3762060 3.784 NM_015417
SPEF1
sperm flagellar 1
chr3_-_120400957 3.775 HGD
homogentisate 1,2-dioxygenase
chr4_-_100273831 3.751 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr6_+_163149001 3.704 NM_001080379
PACRG
PARK2 co-regulated
chr11_-_26593667 3.652 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr1_-_75139421 3.642 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr1_+_244214576 3.641 ZNF238
zinc finger protein 238
chr7_+_114055048 3.636 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr17_+_36861398 3.535 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr6_-_130031278 3.513 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr4_-_186300151 3.511 NM_018409
LRP2BP
LRP2 binding protein
chr9_+_124922189 3.507 NM_198469
MORN5
MORN repeat containing 5
chr12_+_69742130 3.494 NM_000239
LYZ
lysozyme
chr1_+_12806162 3.453 NM_152290
C1orf158
chromosome 1 open reading frame 158
chr6_-_52710892 3.409 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr5_-_110062365 3.378 NM_001039763
TMEM232
transmembrane protein 232
chr5_+_140186658 3.359 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr4_+_15480833 3.278 CC2D2A
coiled-coil and C2 domain containing 2A
chr6_-_52774460 3.260 NM_000847
GSTA3
glutathione S-transferase alpha 3
chr18_+_61370193 3.252 NM_080475
SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr8_-_110620220 3.201 SYBU
syntabulin (syntaxin-interacting)
chr3_-_148939784 3.191 NM_000096
CP
ceruloplasmin (ferroxidase)
chr10_-_123356158 3.186 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr5_+_140220811 3.128 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr12_-_10151689 3.115 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr4_+_41614911 3.091 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_+_61547388 3.090 NM_001145512
NFIA
nuclear factor I/A
chr2_-_86564632 3.082 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr3_-_167371288 3.057 NM_178824
WDR49
WD repeat domain 49
chr5_+_36606667 3.052 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_31681845 3.034


chr1_-_207095198 2.996 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr14_-_23288912 2.992 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_-_16085666 2.968 PROM1
prominin 1
chr11_+_71791376 2.947 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr18_-_53071225 2.939 NM_001243232
TCF4
transcription factor 4
chr16_-_53737713 2.909 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr18_-_53177999 2.890 NM_001243231
TCF4
transcription factor 4
chr17_+_17876126 2.879 NM_001130090
NM_001130091
NM_001130092
NM_031294
LRRC48



leucine rich repeat containing 48



chr2_-_135782246 2.868 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr1_+_244214552 2.839 NM_205768
ZNF238
zinc finger protein 238
chr3_-_114343052 2.838 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_122512526 2.836 NM_024610
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr10_-_116444374 2.755 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr18_-_52988916 2.737 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr22_-_50971007 2.731 NM_001014440
ODF3B
outer dense fiber of sperm tails 3B
chr3_+_113616317 2.719 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr1_+_244216506 2.717 NM_006352
ZNF238
zinc finger protein 238
chr6_-_139613114 2.714 NM_153235
TXLNB
taxilin beta
chr5_+_156820161 2.708 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_+_41614933 2.668 LIMCH1
LIM and calponin homology domains 1
chr5_+_36606456 2.638 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr13_+_24144402 2.636 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr3_+_113557679 2.620 NM_017577
GRAMD1C
GRAM domain containing 1C
chr3_-_169530451 2.619 NM_001172779
NM_001172780
NM_153353
LRRC34


leucine rich repeat containing 34


chr6_+_32407618 2.596 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr1_+_236686738 2.590 NM_006499
NM_201543
LGALS8

lectin, galactoside-binding, soluble, 8

chr12_+_69742140 2.570 LYZ
lysozyme
chr6_-_52628272 2.562 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr20_+_56725982 2.539 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr6_-_29012951 2.516 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr1_+_104198301 2.506 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr4_+_70861647 2.502 NM_001009181
NM_003154
STATH

statherin

chr3_-_149510609 2.467 NM_001144960
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr4_-_70505359 2.460 NM_001105677
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr12_+_41831484 2.433 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr1_-_60392461 2.395 CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr7_-_99145988 2.333 FAM200A
family with sequence similarity 200, member A
chr1_-_60392324 2.325 NM_000775
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr8_+_105352050 2.308 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr3_-_167371701 2.307 WDR49
WD repeat domain 49
chr1_+_104292278 2.303 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr15_-_55800431 2.298 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr1_-_104239071 2.286 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr6_-_134498973 2.269 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_68100994 2.267 NM_170742
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_104198140 2.264 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr15_-_40401041 2.248 NM_001003940
BMF
Bcl2 modifying factor
chr5_-_41213513 2.246 NM_000065
C6
complement component 6
chr4_-_105416050 2.209 CXXC4
CXXC finger protein 4
chr1_-_57045129 2.198 PPAP2B
phosphatidic acid phosphatase type 2B
chr16_+_19467771 2.151 NM_024780
TMC5
transmembrane channel-like 5
chr16_-_46782104 2.139 NM_182493
MYLK3
myosin light chain kinase 3
chr1_-_57045235 2.139 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr10_-_62332666 2.135 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_61389628 2.133 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr4_-_100356290 2.130 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_39072412 2.120 C6orf64
chromosome 6 open reading frame 64
chr9_-_3223007 2.120


chr8_-_72273965 2.081 EYA1
eyes absent homolog 1 (Drosophila)
chr1_+_183605207 2.079 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_-_207119707 2.074 NM_002644
PIGR
polymeric immunoglobulin receptor
chr4_+_72204769 2.073 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr3_-_120401401 2.044 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr2_-_31030271 2.039 NM_144575
CAPN13
calpain 13
chr19_-_44831907 2.032 ZFP112
zinc finger protein 112 homolog (mouse)
chr5_-_160279045 2.014 NM_025153
ATP10B
ATPase, class V, type 10B
chrX_-_117107700 2.004 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chr7_-_117513466 1.987 CTTNBP2
cortactin binding protein 2
chr1_-_108231122 1.983 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr16_-_21289637 1.974 CRYM
crystallin, mu
chr1_+_84768333 1.973 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr1_+_47489239 1.963 NM_178033
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chrX_-_112066353 1.950 NM_001113490
AMOT
angiomotin
chr14_-_92413738 1.941 FBLN5
fibulin 5
chr1_+_61547625 1.922 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr9_+_135753711 1.914 C9orf9
chromosome 9 open reading frame 9
chr6_-_116381765 1.890 NM_002031
FRK
fyn-related kinase
chr7_-_99573637 1.881 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr10_-_61900659 1.879 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_116444112 1.862 ABLIM1
actin binding LIM protein 1
chr5_+_10441973 1.842 NM_001201466
NM_031916
ROPN1L

rhophilin associated tail protein 1-like

chr14_-_53019036 1.840 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr17_-_56406120 1.839 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr4_+_52917440 1.832 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr14_-_92414004 1.832 NM_006329
FBLN5
fibulin 5
chr15_+_78558522 1.830 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr3_-_11623829 1.830 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr9_-_117150217 1.828 AKNA
AT-hook transcription factor
chr11_-_85397215 1.824 NM_152723
CCDC89
coiled-coil domain containing 89
chrX_-_48693934 1.806 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr22_-_36019363 1.803 NM_203377
MB
myoglobin
chr4_-_104020964 1.802 NM_020139
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr11_+_17332454 1.774


chr1_+_174844655 1.773 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr3_+_129159075 1.765 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr1_-_217311095 1.762 NM_001134285
ESRRG
estrogen-related receptor gamma
chr5_-_13944588 1.759 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr14_+_91580713 1.756 C14orf159
chromosome 14 open reading frame 159
chr18_-_53257033 1.747 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr1_+_161068150 1.742 NM_001007255
NM_152366
KLHDC9

kelch domain containing 9

chr14_+_91580467 1.732 C14orf159
chromosome 14 open reading frame 159
chr12_-_111358353 1.732 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr14_+_91580967 1.722 NM_001102367
C14orf159
chromosome 14 open reading frame 159
chr1_-_57044980 1.721 PPAP2B
phosphatidic acid phosphatase type 2B
chr9_+_66553254 1.719 MGC21881
uncharacterized locus MGC21881
chr1_-_217250230 1.715 NM_001243507
NM_001243509
ESRRG

estrogen-related receptor gamma

chr20_-_39317875 1.699 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr22_-_50970542 1.696 ODF3B
outer dense fiber of sperm tails 3B
chr3_+_132318980 1.695 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr9_-_117156684 1.694 NM_030767
AKNA
AT-hook transcription factor
chr3_-_97754147 1.679 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr3_-_187454247 1.672 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr3_-_93782066 1.670 NM_001195643
DHFRL1
dihydrofolate reductase-like 1
chr18_+_3594056 1.660 FLJ35776
uncharacterized LOC649446
chr19_+_13135745 1.645 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_+_24266873 1.640 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr2_-_86565205 1.638 NM_001164730
REEP1
receptor accessory protein 1
chr9_+_74729510 1.628 NM_001242507
GDA
guanine deaminase
chr19_-_14260728 1.628 LPHN1
latrophilin 1
chr7_+_89874487 1.609 NM_001039706
NM_001160138
C7orf63

chromosome 7 open reading frame 63

chr6_+_43612766 1.609 NM_001193341
NM_152732
RSPH9

radial spoke head 9 homolog (Chlamydomonas)

chr7_+_107110501 1.595 NM_005295
GPR22
G protein-coupled receptor 22
chr5_-_121814781 1.591


chr19_+_41430123 1.578 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr20_+_10415949 1.571 NM_001009608
C20orf94
chromosome 20 open reading frame 94
chr11_+_36397534 1.569 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr2_-_160472960 1.568 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr9_-_130712866 1.565 NM_203305
FAM102A
family with sequence similarity 102, member A
chr9_-_75567915 1.559 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr7_+_30960914 1.548 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr5_+_42565562 1.542 NM_001242406
GHR
growth hormone receptor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.30 3.39e-03 GO:0007156 homophilic cell adhesion
2.10 4.51e-03 GO:0016569 covalent chromatin modification
1.74 7.00e-03 GO:0016568 chromatin modification
2.09 7.00e-03 GO:0016570 histone modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 7.49e-04 GO:0005634 nucleus
1.24 1.54e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 1.11e-03 GO:0043169 cation binding
1.19 1.51e-03 GO:0043167 ion binding
1.19 1.79e-03 GO:0046872 metal ion binding
1.07 2.07e-03 GO:0005488 binding
1.24 3.76e-02 GO:0008270 zinc ion binding
1.22 4.42e-02 GO:0046914 transition metal ion binding