Motif ID: TEAD1.p2

Z-value: 1.022


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD3chr6_-_354647160.451.2e-02Click!
TEAD1chr11_+_129607930.384.0e-02Click!
TEAD2chr19_-_498656380.281.3e-01Click!
TEAD4chr12_+_3068989-0.001.0e+00Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51472003 5.294 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr19_-_51456159 3.944 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr19_-_51504799 3.429 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr18_-_21242592 3.398 NM_173505
ANKRD29
ankyrin repeat domain 29
chr15_+_39873276 3.087 NM_003246
THBS1
thrombospondin 1
chr1_+_32043745 2.932 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr9_+_125137600 2.623 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_-_90712510 2.566 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr15_+_63335086 2.435 TPM1
tropomyosin 1 (alpha)
chr17_+_73717596 2.217 ITGB4
integrin, beta 4
chr17_+_73717556 2.146 ITGB4
integrin, beta 4
chr19_-_51512803 2.128 NM_012315
KLK9
kallikrein-related peptidase 9
chr5_-_151066445 2.107 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr4_-_57547845 1.920 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr3_-_149086884 1.884 TM4SF1
transmembrane 4 L six family member 1
chr15_+_63334753 1.881 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr2_-_190044330 1.862 NM_000393
COL5A2
collagen, type V, alpha 2
chr17_-_39093671 1.861 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr12_-_57634474 1.844 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_183155393 1.803 LAMC2
laminin, gamma 2
chr11_-_6341708 1.783 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr1_+_183155173 1.749 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr17_-_40575117 1.654 NM_012232
PTRF
polymerase I and transcript release factor
chr5_-_151066492 1.641 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_-_7682741 1.629 ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr1_-_214724844 1.614 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr12_-_54813002 1.591 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_-_1513187 1.561 NM_213604
ADAMTSL5
ADAMTS-like 5
chr20_-_23967431 1.529 NM_178312
GGTLC1
gamma-glutamyltransferase light chain 1
chr1_+_183155361 1.525 LAMC2
laminin, gamma 2
chr6_-_42110714 1.509 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr19_+_45409003 1.490 NM_000041
APOE
apolipoprotein E
chr17_+_73717515 1.455 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr7_+_134464161 1.421 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr1_-_149908721 1.409 MTMR11
myotubularin related protein 11
chr19_-_14887623 1.390 EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr12_-_54812936 1.374 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_+_27677044 1.276 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr19_-_1512997 1.274 ADAMTSL5
ADAMTS-like 5
chr1_+_150521786 1.274 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr1_-_149908759 1.232 NM_001145862
MTMR11
myotubularin related protein 11
chr16_+_77225094 1.223 MON1B
MON1 homolog B (yeast)
chr12_-_122240827 1.202


chr4_+_158141735 1.198 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr7_+_134464417 1.185 CALD1
caldesmon 1
chr1_-_17307107 1.164 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr17_+_57232859 1.141 NM_018304
PRR11
proline rich 11
chr3_+_50306578 1.135 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr11_-_2170792 1.122 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_-_40828078 1.120 PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_-_209825673 1.109 NM_001127641
LAMB3
laminin, beta 3
chr15_+_75941347 1.101 NM_153271
SNX33
sorting nexin 33
chr11_+_66824285 1.094 NM_014578
RHOD
ras homolog gene family, member D
chr1_-_152386727 1.072 NM_016190
CRNN
cornulin
chr12_-_54813010 1.072 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr6_-_75915566 1.069 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr16_+_28889808 1.049 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr7_+_134464372 1.042 CALD1
caldesmon 1
chr3_+_9944511 1.027 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr12_+_53442732 1.020 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr5_-_39425030 1.005 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr20_-_44540685 1.005 PLTP
phospholipid transfer protein
chr4_-_152149042 0.988 NM_001243349
SH3D19
SH3 domain containing 19
chr12_+_26348488 0.980 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr11_+_66824308 0.980 RHOD
ras homolog gene family, member D
chr1_+_24649529 0.976 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr9_+_34990715 0.951 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_+_136537860 0.941 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr16_-_88851371 0.928 NM_001142864
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr1_-_209825797 0.923 NM_000228
LAMB3
laminin, beta 3
chr2_+_113829894 0.900 NM_032556
IL1F10
interleukin 1 family, member 10 (theta)
chr19_-_55658310 0.890 TNNT1
troponin T type 1 (skeletal, slow)
chr4_-_186733372 0.884 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr3_+_50306305 0.872 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr12_-_8815479 0.869 MFAP5
microfibrillar associated protein 5
chr8_+_70378858 0.861 NM_001128204
NM_015170
SULF1

sulfatase 1

chr13_+_111138079 0.855 COL4A2
collagen, type IV, alpha 2
chr12_-_8815266 0.851 MFAP5
microfibrillar associated protein 5
chr8_+_144816287 0.841 LOC100128338
uncharacterized LOC100128338
chr19_+_34972866 0.839 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr16_+_29823557 0.836 PRRT2
proline-rich transmembrane protein 2
chr16_+_29823408 0.833 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr2_-_20212448 0.832 NM_002381
MATN3
matrilin 3
chr17_-_15554809 0.827 TRIM16
tripartite motif containing 16
chr11_+_2924504 0.824 SLC22A18
solute carrier family 22, member 18
chr1_-_162381805 0.812 NM_053282
SH2D1B
SH2 domain containing 1B
chr1_-_6557448 0.810 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_+_155006281 0.809 NM_001143687
NM_152494
DCST1

DC-STAMP domain containing 1

chr16_-_69788798 0.802 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr12_-_120687956 0.797 NM_025157
PXN
paxillin
chr7_-_155604815 0.796 NM_000193
SHH
sonic hedgehog
chr18_+_21693316 0.780 TTC39C
tetratricopeptide repeat domain 39C
chr6_+_83073501 0.775 TPBG
trophoblast glycoprotein
chr2_-_215896809 0.766 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr2_-_220407818 0.760 NM_001195731
CHPF
chondroitin polymerizing factor
chr15_-_59665053 0.759 MYO1E
myosin IE
chr17_+_4901199 0.737 NM_006612
KIF1C
kinesin family member 1C
chr2_-_20212408 0.728 MATN3
matrilin 3
chr19_+_54372659 0.712 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr5_-_177423242 0.709 NM_006261
PROP1
PROP paired-like homeobox 1
chr10_+_35625608 0.707 NM_145012
CCNY
cyclin Y
chr6_-_30899926 0.707 NM_205854
SFTA2
surfactant associated 2
chr1_-_156675237 0.703 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chrX_+_48620153 0.702 NM_001080489
GLOD5
glyoxalase domain containing 5
chr12_-_96184510 0.702 NM_021229
NTN4
netrin 4
chr3_+_9944295 0.698 NM_153483
IL17RE
interleukin 17 receptor E
chr1_-_214724974 0.696 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chrX_+_53111482 0.696 NM_022117
TSPYL2
TSPY-like 2
chr10_-_99446899 0.695 NM_021732
AVPI1
arginine vasopressin-induced 1
chr14_-_57272344 0.691 NM_172337
OTX2
orthodenticle homeobox 2
chr17_+_9729380 0.690 NM_004246
GLP2R
glucagon-like peptide 2 receptor
chr20_+_33759773 0.688 NM_006404
PROCR
protein C receptor, endothelial
chrX_-_74376075 0.683 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr5_+_96294154 0.679 NM_175920
LNPEP
leucyl/cystinyl aminopeptidase
chr1_-_201438150 0.678 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr19_-_38397233 0.658 NM_031951
WDR87
WD repeat domain 87
chr15_-_59665069 0.655 NM_004998
MYO1E
myosin IE
chr1_-_25291474 0.640 NM_001031680
RUNX3
runt-related transcription factor 3
chr6_+_53883713 0.630 NM_138569
MLIP
muscular LMNA-interacting protein
chr12_-_8815370 0.614 NM_003480
MFAP5
microfibrillar associated protein 5
chr5_-_148442606 0.613 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr18_+_56338818 0.612 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr1_+_16259046 0.603


chr16_-_47495095 0.601 ITFG1
integrin alpha FG-GAP repeat containing 1
chr1_-_115238091 0.594 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr8_+_7783858 0.590 NM_001193630
LOC100132396
zinc finger protein 705D-like
chr5_+_34687663 0.590 NM_001145523
RAI14
retinoic acid induced 14
chr10_-_11574273 0.588 NM_001080491
USP6NL
USP6 N-terminal like
chr11_-_46939908 0.588 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr3_+_47029453 0.587 NBEAL2
neurobeachin-like 2
chr19_+_54369610 0.578 NM_001020820
MYADM
myeloid-associated differentiation marker
chr8_+_1772095 0.575 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr5_+_31193761 0.573 NM_004932
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr2_-_15701445 0.562 NM_015909
NBAS
neuroblastoma amplified sequence
chr18_+_21033263 0.558 RIOK3
RIO kinase 3 (yeast)
chr6_+_83072922 0.557 NM_006670
TPBG
trophoblast glycoprotein
chrX_+_111125124 0.556 NM_001195577
LOC100329135
uncharacterized LOC100329135
chr1_-_12677347 0.555 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr8_-_110986923 0.551 NM_014379
KCNV1
potassium channel, subfamily V, member 1
chr1_-_3447974 0.547 MEGF6
multiple EGF-like-domains 6
chr1_-_27732069 0.545 WASF2
WAS protein family, member 2
chr22_-_36635999 0.541 NM_145637
APOL2
apolipoprotein L, 2
chr6_+_134210264 0.540 TCF21
transcription factor 21
chr6_+_134210247 0.539 NM_198392
NM_003206
TCF21

transcription factor 21

chr12_-_47219734 0.533 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chrX_-_107682600 0.532 NM_001847
COL4A6
collagen, type IV, alpha 6
chrX_+_106163605 0.531 NM_020384
CLDN2
claudin 2
chr1_+_47137496 0.529 NM_001145474
ATPAF1-AS1
ATPAF1 antisense RNA 1 (non-protein coding)
chr1_+_86046434 0.529 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr19_-_14049167 0.529 NM_024825
PODNL1
podocan-like 1
chrX_-_31526414 0.528 NM_004014
DMD
dystrophin
chr2_+_95940195 0.519 NM_001165977
NM_001165978
NM_144707
PROM2


prominin 2


chr16_-_68002455 0.518 NM_001145961
NM_001145962
NM_005072
SLC12A4


solute carrier family 12 (potassium/chloride transporters), member 4


chr16_-_31146992 0.512 PRSS8
protease, serine, 8
chr1_-_109935869 0.512 NM_001205228
SORT1
sortilin 1
chr6_-_41254392 0.510 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr16_+_33261514 0.510 NM_016212
TP53TG3
TP53 target 3
chr19_-_14048877 0.509 PODNL1
podocan-like 1
chr1_-_201346804 0.500 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr9_+_112887780 0.500 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr10_+_6244839 0.489 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr22_-_39095991 0.488 NM_014876
JOSD1
Josephin domain containing 1
chr20_-_23062786 0.487 CD93
CD93 molecule
chr6_+_167525294 0.485 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chrX_+_48368063 0.485 NM_203474
NM_203475
PORCN

porcupine homolog (Drosophila)

chr19_+_17186569 0.483 NM_001130065
NM_004145
MYO9B

myosin IXB

chr19_-_14606939 0.478 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
GIPC1





GIPC PDZ domain containing family, member 1





chr5_-_9630462 0.478 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr19_-_14606893 0.478 GIPC1
GIPC PDZ domain containing family, member 1
chr22_-_36635666 0.475 NM_030882
APOL2
apolipoprotein L, 2
chr3_-_20053618 0.474 NM_001252657
PP2D1
protein phosphatase 2C-like domain containing 1
chr8_-_37727937 0.472 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr15_+_42566365 0.467 NM_198141
GANC
glucosidase, alpha; neutral C
chr18_+_56338678 0.463 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr20_+_34203746 0.459 NM_003116
SPAG4
sperm associated antigen 4
chr6_+_158402928 0.459 SYNJ2
synaptojanin 2
chr11_-_64377332 0.455


chr12_-_498256 0.455 KDM5A
lysine (K)-specific demethylase 5A
chr3_-_12800739 0.455 NM_018306
TMEM40
transmembrane protein 40
chr1_-_153521717 0.454 NM_002960
S100A3
S100 calcium binding protein A3
chr1_+_230202928 0.454 NM_004481
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chrX_+_48367346 0.454 NM_022825
NM_203473
PORCN

porcupine homolog (Drosophila)

chr2_-_192711651 0.452 SDPR
serum deprivation response
chr12_-_53601051 0.451 ITGB7
integrin, beta 7
chr12_-_13153200 0.450 NM_015987
HEBP1
heme binding protein 1
chr8_-_144815888 0.447 NM_198488
FAM83H
family with sequence similarity 83, member H
chr3_+_25469749 0.446 NM_016152
RARB
retinoic acid receptor, beta
chr19_+_1450208 0.441 APC2
adenomatosis polyposis coli 2
chr1_+_230202966 0.438 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr18_+_21032786 0.436 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr5_-_140012730 0.434 CD14
CD14 molecule
chr10_-_33247178 0.428 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr22_+_22988781 0.427 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr16_+_47495166 0.425 NM_000293
NM_001031835
PHKB

phosphorylase kinase, beta

chr1_-_150780705 0.423 NM_000396
CTSK
cathepsin K
chr19_-_51327003 0.419 NM_002257
KLK1
kallikrein 1
chr12_+_13153337 0.419 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr5_+_176562084 0.419 NSD1
nuclear receptor binding SET domain protein 1
chr1_-_161519526 0.419 FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr1_-_161279724 0.418 NM_000530
MPZ
myelin protein zero

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.58 4.15e-04 GO:0030029 actin filament-based process
5.31 4.27e-04 GO:0030048 actin filament-based movement
1.77 1.82e-03 GO:0048468 cell development
4.64 1.49e-02 GO:0043244 regulation of protein complex disassembly
2.05 1.57e-02 GO:0048812 neuron projection morphogenesis
1.47 1.76e-02 GO:0007166 cell surface receptor linked signaling pathway
2.06 2.24e-02 GO:0007409 axonogenesis
2.20 2.30e-02 GO:0007411 axon guidance
2.03 2.33e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.94 3.77e-02 GO:0031175 neuron projection development
1.81 4.08e-02 GO:0030030 cell projection organization
2.02 4.51e-02 GO:0007243 intracellular protein kinase cascade
2.02 4.51e-02 GO:0023014 signal transduction via phosphorylation event
2.69 4.90e-02 GO:0006936 muscle contraction
1.92 4.97e-02 GO:0000904 cell morphogenesis involved in differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.57 3.50e-05 GO:0015629 actin cytoskeleton
4.53 2.50e-04 GO:0016459 myosin complex
3.47 4.34e-03 GO:0001726 ruffle
1.49 4.54e-03 GO:0005856 cytoskeleton
2.59 6.74e-03 GO:0031252 cell leading edge
3.08 7.20e-03 GO:0044420 extracellular matrix part
1.24 2.22e-02 GO:0071944 cell periphery
1.98 2.27e-02 GO:0031012 extracellular matrix
2.59 3.21e-02 GO:0005912 adherens junction
12.88 3.56e-02 GO:0005587 collagen type IV
2.02 4.80e-02 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.46 7.00e-05 GO:0003779 actin binding
2.03 3.38e-04 GO:0008092 cytoskeletal protein binding
1.85 4.61e-03 GO:0005198 structural molecule activity
1.79 7.16e-03 GO:0005509 calcium ion binding
3.38 2.80e-02 GO:0005201 extracellular matrix structural constituent