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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP2B.p2

Z-value: 1.879

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_22469414	7.726	NM_030761	WNT4	wingless-type MMTV integration site family, member 4
chr5_-_180018465	6.201	NM_052863	SCGB3A1	secretoglobin, family 3A, member 1
chr16_-_52580805	4.725	NM_001080430	TOX3	TOX high mobility group box family member 3
chr7_+_152161119	4.622		LOC100128822	uncharacterized LOC100128822
chr2_+_97481977	4.423	NM_017623 NM_199078	CNNM3	cyclin M3
chr6_+_19837599	4.344	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr7_-_158380360	4.007	NM_002847 NM_130842 NM_130843	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr1_+_205538164	3.787		MFSD4	major facilitator superfamily domain containing 4
chr1_+_205538111	3.684	NM_181644	MFSD4	major facilitator superfamily domain containing 4
chr19_+_708766	3.494	NM_001040134 NM_002579	PALM	paralemmin
chr19_+_45504686	3.459	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr16_+_67465019	3.321	NM_000196	HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2
chr19_-_3028901	2.984	NM_003260	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr2_+_121103670	2.845	NM_002193	INHBB	inhibin, beta B
chr1_+_228871109	2.776		RHOU	ras homolog gene family, member U
chr19_+_34972866	2.718	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr7_+_4722091	2.623		FOXK1	forkhead box K1
chr11_-_33890931	2.479		LMO2	LIM domain only 2 (rhombotin-like 1)
chr12_+_102091399	2.457	NM_020244	CHPT1	choline phosphotransferase 1
chr8_+_136469557	2.448	NM_006558	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr4_+_75858205	2.410	NM_015393	PARM1	prostate androgen-regulated mucin-like protein 1
chr17_+_14204326	2.379	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr19_-_14316980	2.336	NM_001008701 NM_014921	LPHN1	latrophilin 1
chr7_+_106685007	2.292	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr2_+_236402948	2.275		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr20_-_3154169	2.264		ProSAPiP1	ProSAPiP1 protein
chr2_+_8822112	2.262	NM_002166	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr2_+_39892637	2.249	NM_001167959	TMEM178	transmembrane protein 178
chr22_+_39853534	2.237		MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_87794548	2.219		LMO4	LIM domain only 4
chr1_-_231175971	2.144	NM_198552	FAM89A	family with sequence similarity 89, member A
chr11_-_33891361	2.135	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr8_+_136470108	2.135		KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr1_+_25944610	2.120		MAN1C1	mannosidase, alpha, class 1C, member 1
chr10_-_100027943	2.108	NM_032211	LOXL4	lysyl oxidase-like 4
chr19_-_18717467	2.102		CRLF1	cytokine receptor-like factor 1
chr7_-_117513527	2.094	NM_033427	CTTNBP2	cortactin binding protein 2
chr7_-_117513466	2.068		CTTNBP2	cortactin binding protein 2
chr17_+_8924822	1.977	NM_004822	NTN1	netrin 1
chr6_+_135502477	1.968		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr4_-_1722978	1.961	NM_001127266 NM_138385	TMEM129	transmembrane protein 129
chr19_-_18717631	1.958	NM_004750	CRLF1	cytokine receptor-like factor 1
chr11_-_695402	1.942	NM_021008	DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr20_-_39317875	1.928	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr22_+_29279573	1.927	NM_001206998	ZNRF3	zinc and ring finger 3
chr19_+_33685489	1.910	NM_002333	LRP3	low density lipoprotein receptor-related protein 3
chr3_+_72937168	1.894	NM_001080393	GXYLT2	glucoside xylosyltransferase 2
chr7_-_131241321	1.878	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr22_+_51113069	1.868	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr1_+_113933474	1.866	NM_001142782 NM_152900	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3
chr2_-_7005764	1.840	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_+_72732958	1.839	NM_001163989	RAB37	RAB37, member RAS oncogene family
chr11_-_93276513	1.801	NM_020179	C11orf75	chromosome 11 open reading frame 75
chr1_+_87794576	1.776		LMO4	LIM domain only 4
chr19_-_4065467	1.765		ZBTB7A	zinc finger and BTB domain containing 7A
chr18_-_45935627	1.759		ZBTB7C	zinc finger and BTB domain containing 7C
chr6_+_135502445	1.751	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr11_-_61348290	1.747	NM_001252065 NM_004200	SYT7	synaptotagmin VII
chr11_-_33891258	1.734		LMO2	LIM domain only 2 (rhombotin-like 1)
chr4_-_25864430	1.732	NM_015187	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr7_+_101459092	1.725	NM_001202543 NM_001202544 NM_001202545 NM_001913 NM_181500 NM_001202546	CUX1	cut-like homeobox 1
chr4_+_41362750	1.711	NM_001112717 NM_001112718 NM_014988	LIMCH1	LIM and calponin homology domains 1
chr9_+_140513451	1.688		EHMT1	euchromatic histone-lysine N-methyltransferase 1
chr14_-_65438794	1.674	NM_198686	RAB15	RAB15, member RAS onocogene family
chr11_-_33891485	1.672	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr4_-_2263808	1.658		MXD4	MAX dimerization protein 4
chr22_+_39745757	1.656	NM_004711 NM_145731	SYNGR1	synaptogyrin 1
chr17_+_72733350	1.635	NM_001006638 NM_001163990	RAB37	RAB37, member RAS oncogene family
chr16_-_56459371	1.628	NM_001144	AMFR	autocrine motility factor receptor
chr19_-_3029611	1.627	NM_001144762	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr9_-_33167084	1.590		B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr15_-_45480160	1.585		SHF	Src homology 2 domain containing F
chr3_+_42544094	1.585	NM_001251883 NM_001251884 NM_001251885 NM_004624	VIPR1	vasoactive intestinal peptide receptor 1
chr3_+_42544131	1.581		VIPR1	vasoactive intestinal peptide receptor 1
chr4_+_72052354	1.572	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr4_-_2263706	1.572	NM_006454	MXD4	MAX dimerization protein 4
chr9_-_130679210	1.546	NM_175039 NM_175040	ST6GALNAC4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr4_+_1005609	1.539	NM_001004356 NM_001004358	FGFRL1	fibroblast growth factor receptor-like 1
chr13_-_36705432	1.528		DCLK1	doublecortin-like kinase 1
chr22_+_39853316	1.518	NM_002409	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr8_-_121824015	1.513
chr19_-_18717577	1.502		CRLF1	cytokine receptor-like factor 1
chr17_-_78194085	1.499	NM_000199	SGSH	N-sulfoglucosamine sulfohydrolase
chr17_+_78194090	1.499	NM_001166347 NM_001166348 NM_001166349 NM_173626	SLC26A11	solute carrier family 26, member 11
chr6_+_135502521	1.491		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr5_+_139027955	1.490		CXXC5	CXXC finger protein 5
chr1_-_23810721	1.486	NM_001143778 NM_017707	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr10_+_93170086	1.483	NM_173497 NM_182765	HECTD2	HECT domain containing 2
chr2_+_85766100	1.474	NM_005911	MAT2A	methionine adenosyltransferase II, alpha
chr5_+_10442065	1.470		ROPN1L	rhophilin associated tail protein 1-like
chr7_+_44788175	1.469		ZMIZ2	zinc finger, MIZ-type containing 2
chr9_+_17578952	1.466	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr3_+_113666544	1.463	NM_173570	ZDHHC23	zinc finger, DHHC-type containing 23
chr19_+_50706868	1.463	NM_001077186 NM_001145809 NM_024729	MYH14	myosin, heavy chain 14, non-muscle
chr5_+_10441973	1.451	NM_001201466 NM_031916	ROPN1L	rhophilin associated tail protein 1-like
chr11_+_45944155	1.449		GYLTL1B	glycosyltransferase-like 1B
chr10_+_12391471	1.449	NM_020397 NM_153498	CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr14_-_89883306	1.447	NM_005197	FOXN3	forkhead box N3
chr7_-_150946031	1.441		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr20_-_32031425	1.428	NM_003098	SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr7_-_152133071	1.414	NM_170606	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr22_-_31741761	1.413		PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr8_-_121824268	1.409		SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr1_+_87794150	1.395	NM_006769	LMO4	LIM domain only 4
chr2_-_145090028	1.394		GTDC1	glycosyltransferase-like domain containing 1
chr15_-_27018108	1.394		GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chr11_+_61276271	1.381	NM_001145077	LRRC10B	leucine rich repeat containing 10B
chr19_-_460995	1.379	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr3_+_141595512	1.374		ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide
chr14_+_105266878	1.373	NM_001137601	ZBTB42	zinc finger and BTB domain containing 42
chr19_+_3094528	1.371		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr2_+_39893021	1.361	NM_152390	TMEM178	transmembrane protein 178
chr2_+_236403290	1.350		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr8_-_110657025	1.337	NM_001099753 NM_001099754 NM_001099755	SYBU	syntabulin (syntaxin-interacting)
chr19_+_33685140	1.333		LRP3	low density lipoprotein receptor-related protein 3
chr5_+_139028025	1.323	NM_016463	CXXC5	CXXC finger protein 5
chr3_+_41240922	1.300	NM_001098209 NM_001098210 NM_001904	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
chr9_+_140513443	1.294	NM_001145527 NM_024757	EHMT1	euchromatic histone-lysine N-methyltransferase 1
chr7_+_94139331	1.288		CASD1	CAS1 domain containing 1
chr15_-_93632161	1.281	NM_020211	RGMA	RGM domain family, member A
chr1_+_64936475	1.241	NM_020925	CACHD1	cache domain containing 1
chr17_-_31386	1.235	NM_003585	DOC2B	double C2-like domains, beta
chr6_+_157099041	1.235	NM_017519 NM_020732	ARID1B	AT rich interactive domain 1B (SWI1-like)
chr21_+_44073650	1.229	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr16_+_58059469	1.225		MMP15	matrix metallopeptidase 15 (membrane-inserted)
chr19_+_50016500	1.215		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr12_+_69633316	1.214	NM_007007	CPSF6	cleavage and polyadenylation specific factor 6, 68kDa
chr19_-_1863425	1.211		KLF16	Kruppel-like factor 16
chr5_-_57755787	1.210	NM_001252226 NM_006622	PLK2	polo-like kinase 2
chr7_+_48075107	1.206	NM_001100159	C7orf57	chromosome 7 open reading frame 57
chr2_+_242641310	1.199	NM_032329	ING5	inhibitor of growth family, member 5
chr22_-_43116796	1.197	NM_017436	A4GALT	alpha 1,4-galactosyltransferase
chr19_+_7580987	1.196	NM_018083	ZNF358	zinc finger protein 358
chr11_+_94277566	1.192		FUT4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr12_+_110152186	1.178	NM_032829	C12orf34	chromosome 12 open reading frame 34
chr5_+_139027907	1.176		CXXC5	CXXC finger protein 5
chr11_+_289113	1.173	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr3_-_158450230	1.172		RARRES1	retinoic acid receptor responder (tazarotene induced) 1
chr6_+_126111782	1.165	NM_001122842 NM_001199621 NM_181782	NCOA7	nuclear receptor coactivator 7
chr20_-_4982133	1.165	NM_005116	SLC23A2	solute carrier family 23 (nucleobase transporters), member 2
chr9_-_89562103	1.159	NM_002048	GAS1	growth arrest-specific 1
chr2_-_113191106	1.157	NM_001164463 NM_005054	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr9_+_96338671	1.155	NM_005392	PHF2	PHD finger protein 2
chrX_+_16964730	1.149	NM_001080975 NM_004726	REPS2	RALBP1 associated Eps domain containing 2
chr2_+_132285469	1.149	NM_138770	CCDC74A	coiled-coil domain containing 74A
chr12_+_108523464	1.147	NM_014653	WSCD2	WSC domain containing 2
chr4_+_1795004	1.146	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr2_+_18059923	1.142	NM_002252	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr15_-_27018160	1.136		GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chr16_+_69600110	1.134		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_3094266	1.131	NM_002067	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr14_-_105261850	1.130		AKT1	v-akt murine thymoma viral oncogene homolog 1
chr20_-_50384861	1.128		ATP9A	ATPase, class II, type 9A
chr22_+_20067732	1.128	NM_001190326 NM_022720	DGCR8	DiGeorge syndrome critical region gene 8
chr10_+_94608224	1.127	NM_019053	EXOC6	exocyst complex component 6
chr15_+_41786055	1.126	NM_002220	ITPKA	inositol-trisphosphate 3-kinase A
chr20_-_40246991	1.120	NM_032221	CHD6	chromodomain helicase DNA binding protein 6
chr3_-_45267068	1.109		TMEM158	transmembrane protein 158 (gene/pseudogene)
chrX_+_68725077	1.108	NM_015686	FAM155B	family with sequence similarity 155, member B
chr7_-_51384458	1.104	NM_015198	COBL	cordon-bleu homolog (mouse)
chr2_-_145090038	1.103	NM_001164629	GTDC1	glycosyltransferase-like domain containing 1
chr10_-_123357503	1.101	NM_000141 NM_001144917 NM_001144918 NM_001144919 NM_022970	FGFR2	fibroblast growth factor receptor 2
chr2_+_102759184	1.101		IL1R1	interleukin 1 receptor, type I
chr1_+_27153130	1.099	NM_032283	ZDHHC18	zinc finger, DHHC-type containing 18
chr19_-_7990974	1.097	NM_206833	CTXN1	cortexin 1
chr20_-_25038501	1.096	NM_001252675 NM_001252677 NM_032501	ACSS1	acyl-CoA synthetase short-chain family member 1
chr12_-_29936685	1.095	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr2_-_220436010	1.093		OBSL1	obscurin-like 1
chr9_-_112260529	1.093	NM_001145368 NM_002829	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr10_-_28591844	1.092		MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_+_211500147	1.091	NM_001033910	TRAF5	TNF receptor-associated factor 5
chr5_+_139027868	1.086		CXXC5	CXXC finger protein 5
chr1_+_21835915	1.086		ALPL	alkaline phosphatase, liver/bone/kidney
chr3_-_197686837	1.083	NM_032263	IQCG	IQ motif containing G
chr3_+_41240995	1.080		CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
chr22_-_19137795	1.073	NM_005315	GSC2	goosecoid homeobox 2
chr2_+_223289212	1.073		SGPP2	sphingosine-1-phosphate phosphatase 2
chr8_-_121824287	1.071	NM_021021	SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr22_-_31742217	1.067	NM_014323 NM_032050 NM_032051 NM_032052	PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr14_+_100259445	1.066	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr3_+_43732358	1.064	NM_016006	ABHD5	abhydrolase domain containing 5
chr5_+_139028483	1.062		CXXC5	CXXC finger protein 5
chr16_-_1464634	1.060	NM_001037125 NM_001193388	UNKL	unkempt homolog (Drosophila)-like
chr16_+_88519917	1.047	NM_153813	ZFPM1	zinc finger protein, multitype 1
chr3_+_141595368	1.044	NM_001679	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide
chr5_+_127419407	1.037	NM_001046	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr11_+_86511490	1.036	NM_007173	PRSS23	protease, serine, 23
chr5_-_159739482	1.036	NM_024565	CCNJL	cyclin J-like
chr6_+_148663953	1.033		SASH1	SAM and SH3 domain containing 1
chr4_-_7044664	1.031	NM_153376	CCDC96	coiled-coil domain containing 96
chr12_-_63328663	1.025	NM_020700	PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_+_7045222	1.025		TADA2B	transcriptional adaptor 2B
chr9_+_114659023	1.021	NM_003358	UGCG	UDP-glucose ceramide glucosyltransferase
chr1_-_27339326	1.018	NM_052943	FAM46B	family with sequence similarity 46, member B
chr1_-_92351476	1.015		TGFBR3	transforming growth factor, beta receptor III
chr15_-_102029872	1.002		PCSK6	proprotein convertase subtilisin/kexin type 6
chr5_-_179498598	1.001		RNF130	ring finger protein 130
chr16_+_67596309	0.998	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr6_+_4776826	0.998		CDYL	chromodomain protein, Y-like
chr6_-_90121656	0.997		RRAGD	Ras-related GTP binding D

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.09	1.47e-18	GO:0009987	cellular process
1.13	1.81e-12	GO:0044237	cellular metabolic process
1.22	4.19e-10	GO:0048519	negative regulation of biological process
1.23	1.45e-09	GO:0048523	negative regulation of cellular process
1.15	4.02e-09	GO:0044260	cellular macromolecule metabolic process
1.10	1.75e-07	GO:0050794	regulation of cellular process
1.09	1.01e-06	GO:0008152	metabolic process
1.15	1.44e-06	GO:0071840	cellular component organization or biogenesis
1.15	1.56e-06	GO:0016043	cellular component organization
1.30	1.85e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.09	3.03e-06	GO:0050789	regulation of biological process
1.21	1.10e-05	GO:0006464	protein modification process
1.22	1.46e-05	GO:0023051	regulation of signaling
1.16	3.53e-05	GO:0048518	positive regulation of biological process
1.08	6.11e-05	GO:0065007	biological regulation
1.25	7.69e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.17	7.74e-05	GO:0048522	positive regulation of cellular process
1.11	1.01e-04	GO:0043170	macromolecule metabolic process
1.09	1.44e-04	GO:0044238	primary metabolic process
1.18	1.84e-04	GO:0043412	macromolecule modification
1.22	2.12e-04	GO:0009966	regulation of signal transduction
1.13	2.86e-04	GO:0031323	regulation of cellular metabolic process
1.15	3.42e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.15	3.99e-04	GO:0071842	cellular component organization at cellular level
1.43	5.36e-04	GO:0016568	chromatin modification
1.31	7.67e-04	GO:0010628	positive regulation of gene expression
1.27	7.78e-04	GO:0006351	transcription, DNA-dependent
1.44	8.79e-04	GO:0051098	regulation of binding
1.32	9.01e-04	GO:0010629	negative regulation of gene expression
1.22	9.79e-04	GO:0009893	positive regulation of metabolic process
1.31	1.09e-03	GO:0051254	positive regulation of RNA metabolic process
1.15	1.22e-03	GO:0044267	cellular protein metabolic process
1.15	1.29e-03	GO:0044249	cellular biosynthetic process
1.47	1.62e-03	GO:0032446	protein modification by small protein conjugation
1.20	1.63e-03	GO:0007399	nervous system development
1.26	1.67e-03	GO:0031324	negative regulation of cellular metabolic process
1.23	1.81e-03	GO:0010646	regulation of cell communication
1.19	1.83e-03	GO:0006996	organelle organization
1.42	2.18e-03	GO:0070647	protein modification by small protein conjugation or removal
1.28	2.19e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24	2.35e-03	GO:0009892	negative regulation of metabolic process
1.37	2.45e-03	GO:0032583	regulation of gene-specific transcription
1.14	2.59e-03	GO:0009058	biosynthetic process
1.25	2.66e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.88	3.77e-03	GO:0007173	epidermal growth factor receptor signaling pathway
1.30	4.02e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.12	4.04e-03	GO:0080090	regulation of primary metabolic process
1.11	4.66e-03	GO:0019222	regulation of metabolic process
1.21	4.69e-03	GO:0031325	positive regulation of cellular metabolic process
1.32	5.26e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.26	6.24e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.13	7.12e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13	8.92e-03	GO:0031326	regulation of cellular biosynthetic process
1.28	1.01e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.45	1.08e-02	GO:0016567	protein ubiquitination
1.31	1.15e-02	GO:0051253	negative regulation of RNA metabolic process
1.11	1.26e-02	GO:0060255	regulation of macromolecule metabolic process
1.13	1.31e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.45	1.32e-02	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
1.27	1.63e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.28	1.64e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.35	1.89e-02	GO:0009968	negative regulation of signal transduction
1.28	1.97e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43	2.14e-02	GO:0051101	regulation of DNA binding
1.13	2.22e-02	GO:0009889	regulation of biosynthetic process
2.05	2.35e-02	GO:0045767	regulation of anti-apoptosis
1.17	2.63e-02	GO:0009653	anatomical structure morphogenesis
1.26	2.71e-02	GO:0045595	regulation of cell differentiation
1.36	2.73e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.36	2.75e-02	GO:0009792	embryo development ending in birth or egg hatching
1.47	2.93e-02	GO:0043193	positive regulation of gene-specific transcription
1.13	2.94e-02	GO:0010468	regulation of gene expression
1.27	2.98e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.52	3.05e-02	GO:0045646	regulation of erythrocyte differentiation
1.27	3.09e-02	GO:0051726	regulation of cell cycle
1.26	3.18e-02	GO:0009890	negative regulation of biosynthetic process
1.13	3.34e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.11	3.36e-02	GO:0034641	cellular nitrogen compound metabolic process
1.14	3.39e-02	GO:0051252	regulation of RNA metabolic process
1.43	3.49e-02	GO:0090046	regulation of transcription regulator activity
1.12	3.52e-02	GO:0051234	establishment of localization
1.27	3.54e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.30	3.80e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.32	4.54e-02	GO:0023057	negative regulation of signaling
1.22	4.56e-02	GO:0022008	neurogenesis
1.11	4.57e-02	GO:0006807	nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	5.33e-39	GO:0005622	intracellular
1.11	7.29e-38	GO:0044424	intracellular part
1.13	7.21e-27	GO:0043231	intracellular membrane-bounded organelle
1.13	1.01e-26	GO:0043227	membrane-bounded organelle
1.12	6.91e-26	GO:0043229	intracellular organelle
1.11	1.50e-25	GO:0043226	organelle
1.13	5.40e-25	GO:0005737	cytoplasm
1.15	1.28e-14	GO:0005634	nucleus
1.13	7.49e-13	GO:0044444	cytoplasmic part
1.04	8.97e-13	GO:0044464	cell part
1.04	1.01e-12	GO:0005623	cell
1.13	1.99e-11	GO:0044446	intracellular organelle part
1.13	2.61e-11	GO:0044422	organelle part
1.19	3.22e-07	GO:0044428	nuclear part
1.19	1.81e-05	GO:0031981	nuclear lumen
1.20	2.56e-05	GO:0012505	endomembrane system
1.16	1.82e-04	GO:0070013	intracellular organelle lumen
1.21	2.30e-04	GO:0005654	nucleoplasm
1.16	2.65e-04	GO:0005829	cytosol
1.16	3.23e-04	GO:0031090	organelle membrane
1.15	4.21e-04	GO:0031974	membrane-enclosed lumen
1.15	5.43e-04	GO:0043233	organelle lumen
1.27	9.80e-04	GO:0044451	nucleoplasm part
1.12	9.82e-04	GO:0043234	protein complex
1.53	1.22e-03	GO:0031252	cell leading edge
1.22	1.64e-03	GO:0005794	Golgi apparatus
1.80	1.54e-02	GO:0031256	leading edge membrane
1.26	1.62e-02	GO:0044431	Golgi apparatus part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	1.43e-26	GO:0005515	protein binding
1.08	2.56e-18	GO:0005488	binding
1.19	7.44e-05	GO:0016740	transferase activity
1.56	2.72e-04	GO:0010843	promoter binding
1.54	3.27e-04	GO:0000975	regulatory region DNA binding
1.54	3.27e-04	GO:0001067	regulatory region nucleic acid binding
1.54	3.27e-04	GO:0044212	transcription regulatory region DNA binding
1.24	9.66e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.14	1.50e-03	GO:0000166	nucleotide binding
1.34	2.38e-03	GO:0019904	protein domain specific binding
2.07	3.23e-03	GO:0046332	SMAD binding
1.25	4.32e-03	GO:0016301	kinase activity
1.37	9.80e-03	GO:0016563	transcription activator activity
1.41	1.02e-02	GO:0016881	acid-amino acid ligase activity
1.24	1.17e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.20	1.43e-02	GO:0030528	transcription regulator activity
1.37	1.85e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.13	1.87e-02	GO:0003677	DNA binding
1.42	1.91e-02	GO:0019787	small conjugating protein ligase activity
1.10	2.02e-02	GO:0003676	nucleic acid binding
1.08	2.23e-02	GO:0003824	catalytic activity
1.37	2.39e-02	GO:0008134	transcription factor binding
1.22	4.85e-02	GO:0019899	enzyme binding
1.64	4.93e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity