Motif ID: TFDP1.p2

Z-value: 2.092


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFDP1chr13_+_114239587,
chr13_+_114238978
0.761.3e-06Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_48673559 5.354 NM_000234
LIG1
ligase I, DNA, ATP-dependent
chr7_-_148581377 4.761 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581359 4.730 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr19_-_14247267 4.609 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr7_-_148581403 4.473 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr19_-_14247400 4.199 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr7_-_148581379 4.064 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr11_-_64851449 3.821 CDCA5
cell division cycle associated 5
chr7_-_148581297 3.781 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr18_+_657674 3.666 TYMS
thymidylate synthetase
chr6_+_34205029 3.637 HMGA1
high mobility group AT-hook 1
chr1_+_212208918 3.315 NM_016448
DTL
denticleless homolog (Drosophila)
chr8_+_26435339 3.263 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr6_+_31126114 3.238 NM_001077511
NM_007109
TCF19

transcription factor 19

chr19_-_14201230 3.202 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr11_-_64851556 3.186 NM_080668
CDCA5
cell division cycle associated 5
chr8_+_26435466 3.057 DPYSL2
dihydropyrimidinase-like 2
chr11_-_19263144 3.044 E2F8
E2F transcription factor 8
chr6_+_37137882 2.945 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr20_+_37555055 2.910 FAM83D
family with sequence similarity 83, member D
chr2_-_215674292 2.848 NM_000465
BARD1
BRCA1 associated RING domain 1
chr4_-_83350829 2.791 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr11_-_118966103 2.746 H2AFX
H2A histone family, member X
chr10_-_129924467 2.733 NM_001145966
NM_002417
MKI67

antigen identified by monoclonal antibody Ki-67

chr9_-_123639566 2.726 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr6_+_31126340 2.713 TCF19
transcription factor 19
chr4_+_1873035 2.694 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr6_+_34204928 2.655 HMGA1
high mobility group AT-hook 1
chr17_+_30813928 2.627 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr1_-_53793743 2.580 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr5_+_172068188 2.573 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr6_-_153304590 2.556 NM_001142522
FBXO5
F-box protein 5
chr5_+_52776263 2.508 NM_006350
NM_013409
FST

follistatin

chr3_-_52090090 2.493 NM_001947
DUSP7
dual specificity phosphatase 7
chr18_+_657633 2.488 TYMS
thymidylate synthetase
chr7_-_99698916 2.480 MCM7
minichromosome maintenance complex component 7
chr1_+_212209129 2.476 DTL
denticleless homolog (Drosophila)
chr16_+_46723577 2.298 ORC6
PPA2
origin recognition complex, subunit 6
pyrophosphatase (inorganic) 2
chr12_+_57610577 2.279 NM_007224
NXPH4
neurexophilin 4
chr5_-_16936290 2.219 MYO10
myosin X
chr14_-_91282760 2.218 NM_001010854
TTC7B
tetratricopeptide repeat domain 7B
chr4_-_122744978 2.215 NM_001237
CCNA2
cyclin A2
chr11_-_118966175 2.211 NM_002105
H2AFX
H2A histone family, member X
chr1_+_212209112 2.209 DTL
denticleless homolog (Drosophila)
chr5_+_126112819 2.187 NM_001198557
LMNB1
lamin B1
chr17_+_30814708 2.171


chr7_-_150864866 2.166 NM_001098834
GBX1
gastrulation brain homeobox 1
chr16_+_2479417 2.146 CCNF
cyclin F
chr20_+_42295747 2.114 MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr7_-_28220146 2.086 JAZF1
JAZF zinc finger 1
chr7_-_99698993 2.081 MCM7
minichromosome maintenance complex component 7
chr2_+_239756672 2.076 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr9_-_99180661 2.068 NM_153695
ZNF367
zinc finger protein 367
chr2_-_136288768 2.054 NM_032143
ZRANB3
zinc finger, RAN-binding domain containing 3
chr6_+_31126734 2.046 TCF19
transcription factor 19
chr19_+_17666381 2.014 GLT25D1
glycosyltransferase 25 domain containing 1
chr16_+_2479387 2.008 NM_001761
CCNF
cyclin F
chr2_+_174219537 1.989 NM_031942
NM_145810
CDCA7

cell division cycle associated 7

chr12_-_120554453 1.988 RAB35
RAB35, member RAS oncogene family
chrX_-_109561427 1.971 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr5_+_52776408 1.918 FST
follistatin
chr7_+_24612714 1.914 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chrX_-_109561298 1.884 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr12_-_120554558 1.860 RAB35
RAB35, member RAS oncogene family
chr1_+_2160133 1.836 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr13_+_100633977 1.830 NM_007129
ZIC2
Zic family member 2
chr7_-_50861114 1.829 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr20_+_42295708 1.807 NM_002466
MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr5_+_52776479 1.806 FST
follistatin
chr2_+_48541767 1.797 NM_002158
FOXN2
forkhead box N2
chr4_+_128802064 1.792 NM_001190801
PLK4
polo-like kinase 4
chr12_+_98909405 1.774 TMPO
thymopoietin
chr19_+_34287662 1.768 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr11_-_61584228 1.766 FADS1
fatty acid desaturase 1
chr14_+_105941061 1.746 NM_001312
CRIP2
cysteine-rich protein 2
chr10_+_14920781 1.728 NM_001193424
NM_001193426
NM_001193425
NM_001193427
NM_024670
SUV39H2




suppressor of variegation 3-9 homolog 2 (Drosophila)




chr18_+_33877630 1.728 NM_025135
FHOD3
formin homology 2 domain containing 3
chr1_-_21113758 1.704 HP1BP3
heterochromatin protein 1, binding protein 3
chr10_+_112257624 1.668 NM_004419
DUSP5
dual specificity phosphatase 5
chr17_-_74449220 1.659 UBE2O
ubiquitin-conjugating enzyme E2O
chr12_-_120554551 1.650 RAB35
RAB35, member RAS oncogene family
chr6_+_34204690 1.650 HMGA1
high mobility group AT-hook 1
chr16_-_3030473 1.637 NM_004203
NM_182687
PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

chr9_-_94186140 1.632 NM_005384
NFIL3
nuclear factor, interleukin 3 regulated
chr9_+_103189494 1.616 NM_001198807
NM_080655
NM_001198805
C9orf30


chromosome 9 open reading frame 30


chr2_+_23608297 1.616 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr12_+_111471827 1.615 NM_015267
CUX2
cut-like homeobox 2
chr12_-_77459198 1.613 NM_203394
E2F7
E2F transcription factor 7
chr16_+_29817810 1.610 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr7_-_99699426 1.605 NM_005916
MCM7
minichromosome maintenance complex component 7
chr5_+_126112847 1.604 LMNB1
lamin B1
chr17_-_17726855 1.591 SREBF1
sterol regulatory element binding transcription factor 1
chrX_+_48555124 1.586 NM_003173
SUV39H1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr14_-_50154920 1.578 POLE2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr12_+_98909331 1.562 NM_001032283
NM_001032284
NM_003276
TMPO


thymopoietin


chr19_-_6424536 1.556 KHSRP
KH-type splicing regulatory protein
chr5_-_134369571 1.553 PITX1
paired-like homeodomain 1
chr6_-_18264638 1.551 NM_001134709
NM_003472
DEK

DEK oncogene

chr20_+_37554954 1.548 NM_030919
FAM83D
family with sequence similarity 83, member D
chr3_-_53290099 1.542 NM_001064
NM_001135055
TKT

transketolase

chr4_-_83350548 1.542 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr6_+_34204576 1.530 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr9_-_126692184 1.521 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr12_+_98909410 1.508 TMPO
thymopoietin
chr6_+_34205369 1.499 HMGA1
high mobility group AT-hook 1
chr12_+_118454505 1.496 NM_001130112
NM_001206801
NM_007370
NM_181578
RFC5



replication factor C (activator 1) 5, 36.5kDa



chr17_-_26926044 1.482 NM_006461
SPAG5
sperm associated antigen 5
chr14_-_50155097 1.482 NM_001197330
NM_001197331
NM_002692
POLE2


polymerase (DNA directed), epsilon 2 (p59 subunit)


chr6_+_69344939 1.479 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr14_-_69445978 1.478 ACTN1
actinin, alpha 1
chr17_-_26926015 1.475 SPAG5
sperm associated antigen 5
chr9_+_128509616 1.471 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr2_-_1748240 1.470 PXDN
peroxidasin homolog (Drosophila)
chr6_+_34204647 1.459 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr10_-_15210610 1.459 NM_004808
NMT2
N-myristoyltransferase 2
chr4_+_1873149 1.459 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chrX_-_109561314 1.453 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr15_+_66797632 1.447 ZWILCH
Zwilch, kinetochore associated, homolog (Drosophila)
chr18_+_56338783 1.445 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr14_-_69445974 1.441 ACTN1
actinin, alpha 1
chr16_-_85722587 1.429 NM_016095
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr14_-_69446008 1.425 ACTN1
actinin, alpha 1
chr4_+_128982483 1.422 LARP1B
La ribonucleoprotein domain family, member 1B
chr6_-_31869768 1.404 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr12_-_2986095 1.403 FOXM1
forkhead box M1
chr22_+_20105076 1.400 RANBP1
RAN binding protein 1
chr6_+_20404033 1.393 NM_001243076
E2F3
E2F transcription factor 3
chr17_+_76210276 1.388 NM_001012270
NM_001012271
NM_001168
BIRC5


baculoviral IAP repeat containing 5


chr4_-_122744782 1.388 CCNA2
cyclin A2
chr1_+_145477018 1.387 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr2_-_235405692 1.386 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr1_-_53793583 1.384 LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr14_-_69446038 1.375 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr19_+_16187306 1.359 TPM4
tropomyosin 4
chr7_+_155089614 1.341 INSIG1
insulin induced gene 1
chr19_+_16187266 1.335 TPM4
tropomyosin 4
chr11_-_19262424 1.330 NM_024680
E2F8
E2F transcription factor 8
chr17_+_30814552 1.327 CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr7_-_50860665 1.325 GRB10
growth factor receptor-bound protein 10
chr22_+_38142245 1.322 TRIOBP
TRIO and F-actin binding protein
chr7_-_99699030 1.319 MCM7
minichromosome maintenance complex component 7
chr1_+_41445402 1.315 CTPS
CTP synthase
chr10_-_25012543 1.311 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr19_-_14228560 1.304 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr15_+_66797430 1.302 NM_017975
ZWILCH
Zwilch, kinetochore associated, homolog (Drosophila)
chr10_+_105127709 1.293 NM_006951
TAF5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
chr1_-_93426998 1.293 NM_001006605
NM_001252269
NM_001252270
NM_001252273
FAM69A



family with sequence similarity 69, member A



chr3_-_13921617 1.288 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr11_+_66624875 1.284 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_-_6321034 1.284 NM_207370
GPR153
G protein-coupled receptor 153
chr5_-_65017874 1.276 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr9_+_36572844 1.264 NM_014791
MELK
maternal embryonic leucine zipper kinase
chr13_+_114238978 1.262 TFDP1
transcription factor Dp-1
chr12_+_123873602 1.261 SETD8
SET domain containing (lysine methyltransferase) 8
chr8_-_124408688 1.260 NM_014109
ATAD2
ATPase family, AAA domain containing 2
chr4_-_83350452 1.247 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_-_174828775 1.244 NM_001017371
SP3
Sp3 transcription factor
chr9_-_94185959 1.238 NFIL3
nuclear factor, interleukin 3 regulated
chr13_-_80915041 1.236 NM_005842
SPRY2
sprouty homolog 2 (Drosophila)
chr1_+_9648931 1.232 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chrX_-_15872905 1.229


chr3_-_52567708 1.227 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr13_+_114239047 1.226 NM_007111
TFDP1
transcription factor Dp-1
chr19_+_4910339 1.225 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr2_-_136633934 1.222 MCM6
minichromosome maintenance complex component 6
chr17_-_62658175 1.217 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr2_-_27632522 1.216 PPM1G
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr1_+_46713433 1.213 RAD54L
RAD54-like (S. cerevisiae)
chr19_-_2456954 1.209 NM_032737
LMNB2
lamin B2
chr2_-_1748285 1.206 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr16_+_22825806 1.203 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr11_-_115375065 1.194 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr16_+_838645 1.187 CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr10_-_44880452 1.187 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr16_-_87903028 1.184 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr6_+_34204663 1.177 HMGA1
high mobility group AT-hook 1
chr11_+_69924407 1.175 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr14_-_100070442 1.172 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr15_+_73976720 1.169 CD276
CD276 molecule
chr19_-_17186229 1.163 NM_001011699
NM_033417
HAUS8

HAUS augmin-like complex, subunit 8

chr19_+_30302861 1.162 NM_001238
CCNE1
cyclin E1
chr1_-_11120001 1.160 SRM
spermidine synthase
chr17_-_42907606 1.158 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr20_-_5100443 1.157 NM_182649
PCNA
proliferating cell nuclear antigen
chr1_-_26232643 1.156 NM_203401
STMN1
stathmin 1
chr7_+_150811719 1.154 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr15_-_83876165 1.149 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr13_-_60738078 1.140 NM_001042517
DIAPH3
diaphanous homolog 3 (Drosophila)
chr14_-_69445948 1.139 ACTN1
actinin, alpha 1
chr9_-_123639462 1.136 PHF19
PHD finger protein 19
chr8_-_131455833 1.135 NM_001247996
NM_018482
ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

chr4_-_100871431 1.135 H2AFZ
H2A histone family, member Z
chr13_+_110959592 1.135 NM_001846
COL4A2
collagen, type IV, alpha 2
chr17_+_76210329 1.132 BIRC5
baculoviral IAP repeat containing 5
chr16_+_838610 1.126 NM_022092
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr19_+_16187315 1.124 TPM4
tropomyosin 4
chr20_-_31172874 1.122 LOC284804
uncharacterized LOC284804
chr2_+_208576239 1.121 NM_001142300
NM_152523
CCNYL1

cyclin Y-like 1

chr10_+_124220990 1.117 NM_002775
HTRA1
HtrA serine peptidase 1
chr12_-_120554612 1.117 NM_001167606
NM_006861
RAB35

RAB35, member RAS oncogene family


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 2.38e-49 GO:0009987 cellular process
1.30 5.08e-49 GO:0044260 cellular macromolecule metabolic process
1.22 2.88e-42 GO:0044237 cellular metabolic process
1.23 1.16e-33 GO:0043170 macromolecule metabolic process
1.18 2.44e-30 GO:0044238 primary metabolic process
1.16 5.12e-28 GO:0008152 metabolic process
1.31 6.83e-27 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 2.70e-26 GO:0006464 protein modification process
1.30 5.41e-25 GO:0071842 cellular component organization at cellular level
1.31 1.66e-24 GO:0044267 cellular protein metabolic process
1.26 2.24e-24 GO:0016043 cellular component organization
1.29 3.60e-24 GO:0071841 cellular component organization or biogenesis at cellular level
1.35 9.50e-24 GO:0043412 macromolecule modification
1.26 1.89e-23 GO:0034641 cellular nitrogen compound metabolic process
1.26 2.15e-23 GO:0006807 nitrogen compound metabolic process
1.25 3.13e-23 GO:0071840 cellular component organization or biogenesis
1.38 1.59e-22 GO:0034645 cellular macromolecule biosynthetic process
1.32 2.04e-22 GO:0090304 nucleic acid metabolic process
1.37 5.45e-22 GO:0009059 macromolecule biosynthetic process
1.15 7.06e-21 GO:0050794 regulation of cellular process
1.46 2.95e-20 GO:0007049 cell cycle
1.28 8.10e-19 GO:0044249 cellular biosynthetic process
1.13 2.03e-18 GO:0050789 regulation of biological process
1.12 4.08e-18 GO:0065007 biological regulation
1.27 1.42e-17 GO:0009058 biosynthetic process
1.21 3.11e-17 GO:0031323 regulation of cellular metabolic process
1.29 1.31e-16 GO:0048869 cellular developmental process
1.22 1.61e-16 GO:0060255 regulation of macromolecule metabolic process
1.21 2.86e-16 GO:0080090 regulation of primary metabolic process
1.33 4.22e-16 GO:0006996 organelle organization
1.47 6.72e-16 GO:0022402 cell cycle process
1.19 1.12e-15 GO:0019222 regulation of metabolic process
1.55 2.41e-15 GO:0000278 mitotic cell cycle
1.27 2.50e-14 GO:0030154 cell differentiation
1.19 2.65e-14 GO:0032502 developmental process
1.49 2.68e-14 GO:0022403 cell cycle phase
1.68 6.96e-14 GO:0051301 cell division
1.29 1.03e-13 GO:0016070 RNA metabolic process
1.23 1.37e-13 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 1.49e-13 GO:0007399 nervous system development
1.21 5.86e-13 GO:0019538 protein metabolic process
1.25 9.06e-13 GO:0048523 negative regulation of cellular process
1.22 9.35e-13 GO:0051171 regulation of nitrogen compound metabolic process
1.41 1.34e-12 GO:0048699 generation of neurons
1.31 1.73e-12 GO:0009653 anatomical structure morphogenesis
1.40 2.40e-12 GO:0022008 neurogenesis
1.38 2.48e-12 GO:0032774 RNA biosynthetic process
1.23 1.26e-11 GO:0048519 negative regulation of biological process
1.26 1.30e-11 GO:0010467 gene expression
1.23 3.04e-11 GO:0051252 regulation of RNA metabolic process
1.18 3.16e-11 GO:0007275 multicellular organismal development
1.22 3.51e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.36 5.72e-11 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.19 6.54e-11 GO:0048856 anatomical structure development
1.21 8.21e-11 GO:0010468 regulation of gene expression
1.45 1.58e-10 GO:0051726 regulation of cell cycle
1.27 3.41e-10 GO:0023051 regulation of signaling
1.20 4.14e-10 GO:0031326 regulation of cellular biosynthetic process
1.37 5.86e-10 GO:0006351 transcription, DNA-dependent
1.21 6.45e-10 GO:0048522 positive regulation of cellular process
1.28 1.00e-09 GO:0009966 regulation of signal transduction
1.20 1.12e-09 GO:0009889 regulation of biosynthetic process
1.34 1.26e-09 GO:0006793 phosphorus metabolic process
1.34 1.26e-09 GO:0006796 phosphate metabolic process
1.62 1.43e-09 GO:0051325 interphase
1.20 2.10e-09 GO:0010556 regulation of macromolecule biosynthetic process
1.22 2.34e-09 GO:0006355 regulation of transcription, DNA-dependent
1.61 2.89e-09 GO:0051329 interphase of mitotic cell cycle
1.40 3.37e-09 GO:0030182 neuron differentiation
1.18 5.81e-09 GO:0048731 system development
1.41 1.09e-08 GO:0030030 cell projection organization
1.41 1.65e-08 GO:0051276 chromosome organization
1.19 1.77e-08 GO:0048518 positive regulation of biological process
1.42 1.95e-08 GO:0000902 cell morphogenesis
1.59 2.35e-08 GO:0048285 organelle fission
1.68 3.99e-08 GO:0048011 nerve growth factor receptor signaling pathway
1.59 5.83e-08 GO:0000280 nuclear division
1.59 5.83e-08 GO:0007067 mitosis
1.57 8.64e-08 GO:0000087 M phase of mitotic cell cycle
1.40 1.02e-07 GO:0032989 cellular component morphogenesis
1.32 1.07e-07 GO:0048468 cell development
1.41 1.13e-07 GO:0048666 neuron development
1.43 1.86e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.72 2.07e-07 GO:0006260 DNA replication
1.27 2.33e-07 GO:0051641 cellular localization
1.46 3.55e-07 GO:0000279 M phase
1.43 4.02e-07 GO:0031175 neuron projection development
1.43 4.14e-07 GO:0000904 cell morphogenesis involved in differentiation
1.34 5.43e-07 GO:0031399 regulation of protein modification process
1.25 5.83e-07 GO:0035556 intracellular signal transduction
1.26 6.09e-07 GO:0033036 macromolecule localization
1.37 1.38e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.38 1.95e-06 GO:0006259 DNA metabolic process
1.34 1.97e-06 GO:0006468 protein phosphorylation
1.30 2.11e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.37 2.17e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.41 2.40e-06 GO:0032990 cell part morphogenesis
1.28 2.60e-06 GO:0008104 protein localization
1.41 3.01e-06 GO:0048858 cell projection morphogenesis
1.28 6.34e-06 GO:0009892 negative regulation of metabolic process
1.41 8.05e-06 GO:0045859 regulation of protein kinase activity
1.33 1.24e-05 GO:0009890 negative regulation of biosynthetic process
1.34 1.26e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.25 1.32e-05 GO:0031325 positive regulation of cellular metabolic process
1.35 1.52e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 1.53e-05 GO:0048812 neuron projection morphogenesis
1.29 1.61e-05 GO:0031324 negative regulation of cellular metabolic process
1.42 1.67e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.39 1.72e-05 GO:0043549 regulation of kinase activity
1.30 1.90e-05 GO:0016310 phosphorylation
1.27 2.49e-05 GO:0032268 regulation of cellular protein metabolic process
1.47 2.81e-05 GO:0070647 protein modification by small protein conjugation or removal
1.33 3.16e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.34 3.80e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.32 4.44e-05 GO:0019220 regulation of phosphate metabolic process
1.32 4.44e-05 GO:0051174 regulation of phosphorus metabolic process
1.30 4.61e-05 GO:0046907 intracellular transport
1.26 4.96e-05 GO:0010646 regulation of cell communication
1.29 5.09e-05 GO:0051128 regulation of cellular component organization
1.33 5.49e-05 GO:0001932 regulation of protein phosphorylation
1.50 5.98e-05 GO:0032446 protein modification by small protein conjugation
1.37 6.77e-05 GO:0051338 regulation of transferase activity
1.41 6.78e-05 GO:0007409 axonogenesis
1.42 6.81e-05 GO:0007264 small GTPase mediated signal transduction
1.25 8.39e-05 GO:0051246 regulation of protein metabolic process
1.12 9.61e-05 GO:0051716 cellular response to stimulus
1.36 1.04e-04 GO:0034613 cellular protein localization
1.23 1.13e-04 GO:0009893 positive regulation of metabolic process
1.32 1.14e-04 GO:0042325 regulation of phosphorylation
1.36 1.16e-04 GO:0070727 cellular macromolecule localization
1.18 1.49e-04 GO:0048583 regulation of response to stimulus
1.25 1.66e-04 GO:0022607 cellular component assembly
1.50 1.67e-04 GO:0016567 protein ubiquitination
1.29 2.00e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.28 2.00e-04 GO:0043933 macromolecular complex subunit organization
1.28 2.07e-04 GO:0033554 cellular response to stress
1.28 2.44e-04 GO:0044093 positive regulation of molecular function
1.12 2.45e-04 GO:0023052 signaling
1.29 2.85e-04 GO:0071844 cellular component assembly at cellular level
1.29 2.96e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 3.11e-04 GO:0034621 cellular macromolecular complex subunit organization
1.37 3.16e-04 GO:0006325 chromatin organization
1.12 4.09e-04 GO:0007165 signal transduction
1.20 4.50e-04 GO:0065009 regulation of molecular function
1.22 4.86e-04 GO:0044085 cellular component biogenesis
1.23 4.86e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.33 5.74e-04 GO:0051253 negative regulation of RNA metabolic process
1.34 5.92e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.25 1.18e-03 GO:0050793 regulation of developmental process
1.40 1.22e-03 GO:0010564 regulation of cell cycle process
1.42 1.38e-03 GO:0060284 regulation of cell development
1.25 1.56e-03 GO:0045184 establishment of protein localization
1.22 1.59e-03 GO:0051649 establishment of localization in cell
1.32 1.73e-03 GO:0016071 mRNA metabolic process
1.40 1.74e-03 GO:0018193 peptidyl-amino acid modification
1.31 1.84e-03 GO:0071822 protein complex subunit organization
1.68 2.10e-03 GO:0007265 Ras protein signal transduction
1.27 2.17e-03 GO:2000026 regulation of multicellular organismal development
1.28 2.21e-03 GO:0045595 regulation of cell differentiation
1.39 2.53e-03 GO:0016568 chromatin modification
1.28 2.87e-03 GO:0009790 embryo development
1.64 2.96e-03 GO:0006470 protein dephosphorylation
1.30 3.04e-03 GO:0010629 negative regulation of gene expression
1.46 3.61e-03 GO:0000165 MAPKKK cascade
1.57 3.70e-03 GO:0022415 viral reproductive process
1.27 5.25e-03 GO:0065003 macromolecular complex assembly
1.39 5.39e-03 GO:0007411 axon guidance
1.21 5.47e-03 GO:0044248 cellular catabolic process
1.28 5.50e-03 GO:0051254 positive regulation of RNA metabolic process
1.26 5.98e-03 GO:0016192 vesicle-mediated transport
1.24 6.33e-03 GO:0015031 protein transport
1.40 1.00e-02 GO:0006366 transcription from RNA polymerase II promoter
1.49 1.01e-02 GO:0045664 regulation of neuron differentiation
1.32 1.06e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.57 1.27e-02 GO:0000082 G1/S transition of mitotic cell cycle
1.51 1.37e-02 GO:0051169 nuclear transport
1.27 1.42e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.43 1.49e-02 GO:0050767 regulation of neurogenesis
1.66 1.50e-02 GO:0007059 chromosome segregation
1.51 1.54e-02 GO:0006913 nucleocytoplasmic transport
1.23 1.89e-02 GO:0016265 death
1.50 2.09e-02 GO:0016569 covalent chromatin modification
1.33 2.25e-02 GO:0009968 negative regulation of signal transduction
1.22 2.25e-02 GO:0008219 cell death
1.40 2.46e-02 GO:0051960 regulation of nervous system development
1.39 2.49e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.56 2.82e-02 GO:0019058 viral infectious cycle
1.55 2.85e-02 GO:0016311 dephosphorylation
1.32 2.92e-02 GO:0007243 intracellular protein kinase cascade
1.32 2.92e-02 GO:0023014 signal transduction via phosphorylation event
1.69 2.97e-02 GO:0030326 embryonic limb morphogenesis
1.69 2.97e-02 GO:0035113 embryonic appendage morphogenesis
1.44 3.09e-02 GO:0045786 negative regulation of cell cycle
1.33 3.19e-02 GO:0006397 mRNA processing
1.10 3.25e-02 GO:0051179 localization
2.14 3.36e-02 GO:0042733 embryonic digit morphogenesis
1.63 3.41e-02 GO:0048736 appendage development
1.63 3.41e-02 GO:0060173 limb development
1.66 3.41e-02 GO:0042176 regulation of protein catabolic process
1.31 3.43e-02 GO:0008283 cell proliferation
1.49 3.55e-02 GO:0016570 histone modification
1.47 3.60e-02 GO:0022411 cellular component disassembly
1.47 3.60e-02 GO:0071845 cellular component disassembly at cellular level
1.19 3.70e-02 GO:0050790 regulation of catalytic activity
1.25 3.75e-02 GO:0043085 positive regulation of catalytic activity
1.49 3.99e-02 GO:0043687 post-translational protein modification
1.31 4.31e-02 GO:0023057 negative regulation of signaling
1.32 4.35e-02 GO:0016032 viral reproduction
1.54 4.46e-02 GO:0006184 GTP catabolic process
1.41 4.51e-02 GO:0006195 purine nucleotide catabolic process
1.25 4.57e-02 GO:0010628 positive regulation of gene expression
1.34 4.58e-02 GO:0034622 cellular macromolecular complex assembly
1.29 4.67e-02 GO:0048585 negative regulation of response to stimulus
1.57 4.92e-02 GO:0006403 RNA localization
1.57 4.92e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 2.85e-81 GO:0005622 intracellular
1.16 1.96e-80 GO:0044424 intracellular part
1.17 1.96e-59 GO:0043229 intracellular organelle
1.16 2.35e-59 GO:0043226 organelle
1.18 1.24e-57 GO:0043231 intracellular membrane-bounded organelle
1.18 2.18e-57 GO:0043227 membrane-bounded organelle
1.25 5.06e-48 GO:0005634 nucleus
1.17 1.33e-44 GO:0005737 cytoplasm
1.20 1.97e-30 GO:0044446 intracellular organelle part
1.19 9.79e-30 GO:0044422 organelle part
1.34 2.41e-27 GO:0044428 nuclear part
1.36 1.31e-24 GO:0031981 nuclear lumen
1.33 1.97e-24 GO:0005829 cytosol
1.17 2.20e-23 GO:0044444 cytoplasmic part
1.40 3.56e-21 GO:0005654 nucleoplasm
1.30 6.53e-21 GO:0070013 intracellular organelle lumen
1.04 1.19e-19 GO:0044464 cell part
1.04 1.37e-19 GO:0005623 cell
1.28 2.88e-19 GO:0043233 organelle lumen
1.28 3.28e-19 GO:0031974 membrane-enclosed lumen
1.18 6.81e-13 GO:0032991 macromolecular complex
1.20 1.32e-12 GO:0043234 protein complex
1.46 1.02e-10 GO:0005694 chromosome
1.48 1.30e-09 GO:0044427 chromosomal part
1.18 2.48e-09 GO:0043228 non-membrane-bounded organelle
1.18 2.48e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.38 5.62e-09 GO:0015630 microtubule cytoskeleton
1.24 2.00e-08 GO:0012505 endomembrane system
1.30 3.47e-08 GO:0005794 Golgi apparatus
1.61 3.76e-07 GO:0000228 nuclear chromosome
1.32 2.37e-06 GO:0044451 nucleoplasm part
1.35 2.69e-06 GO:0044431 Golgi apparatus part
1.65 2.95e-06 GO:0044454 nuclear chromosome part
1.45 5.26e-06 GO:0005815 microtubule organizing center
1.43 1.30e-05 GO:0048471 perinuclear region of cytoplasm
1.60 1.69e-05 GO:0005819 spindle
1.36 4.45e-05 GO:0000139 Golgi membrane
1.56 8.92e-05 GO:0031252 cell leading edge
1.15 2.11e-04 GO:0031090 organelle membrane
1.47 2.96e-04 GO:0000785 chromatin
1.18 3.09e-04 GO:0005856 cytoskeleton
1.58 4.64e-04 GO:0005912 adherens junction
2.08 6.67e-04 GO:0000792 heterochromatin
1.76 1.24e-03 GO:0000790 nuclear chromatin
1.52 2.03e-03 GO:0070161 anchoring junction
1.38 3.69e-03 GO:0005874 microtubule
1.54 5.12e-03 GO:0000775 chromosome, centromeric region
2.01 5.92e-03 GO:0008287 protein serine/threonine phosphatase complex
1.40 7.56e-03 GO:0005635 nuclear envelope
1.53 8.91e-03 GO:0000793 condensed chromosome
1.65 1.12e-02 GO:0001726 ruffle
1.73 1.85e-02 GO:0034399 nuclear periphery
1.40 1.86e-02 GO:0005813 centrosome
2.18 1.88e-02 GO:0005637 nuclear inner membrane
1.74 2.01e-02 GO:0030117 membrane coat
1.74 2.01e-02 GO:0048475 coated membrane
2.13 2.08e-02 GO:0005720 nuclear heterochromatin
1.21 2.19e-02 GO:0031982 vesicle
1.18 2.50e-02 GO:0044430 cytoskeletal part
1.77 2.57e-02 GO:0000123 histone acetyltransferase complex
1.21 3.08e-02 GO:0031410 cytoplasmic vesicle
1.58 3.85e-02 GO:0005925 focal adhesion
1.19 3.98e-02 GO:0042995 cell projection
1.87 4.31e-02 GO:0017053 transcriptional repressor complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 1.19e-54 GO:0005515 protein binding
1.10 2.80e-39 GO:0005488 binding
1.26 6.14e-16 GO:0000166 nucleotide binding
1.18 2.43e-12 GO:0003676 nucleic acid binding
1.23 1.02e-09 GO:0017076 purine nucleotide binding
1.23 1.62e-09 GO:0032553 ribonucleotide binding
1.23 1.62e-09 GO:0032555 purine ribonucleotide binding
1.22 5.21e-09 GO:0035639 purine ribonucleoside triphosphate binding
1.19 3.16e-08 GO:0003677 DNA binding
1.30 5.29e-08 GO:0030528 transcription regulator activity
1.23 6.29e-08 GO:0030554 adenyl nucleotide binding
1.22 9.82e-08 GO:0016740 transferase activity
1.23 1.32e-07 GO:0032559 adenyl ribonucleotide binding
1.28 5.21e-07 GO:0001071 nucleic acid binding transcription factor activity
1.28 5.21e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.22 7.44e-07 GO:0005524 ATP binding
1.29 1.28e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.31 4.04e-06 GO:0019899 enzyme binding
1.10 9.09e-06 GO:0003824 catalytic activity
1.50 1.70e-05 GO:0016881 acid-amino acid ligase activity
1.29 2.66e-05 GO:0016301 kinase activity
1.29 4.76e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.62 6.57e-05 GO:0004721 phosphoprotein phosphatase activity
1.37 7.25e-05 GO:0019904 protein domain specific binding
1.45 7.25e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.27 1.03e-04 GO:0003723 RNA binding
1.47 5.84e-04 GO:0019787 small conjugating protein ligase activity
1.34 7.53e-04 GO:0004674 protein serine/threonine kinase activity
1.28 1.29e-03 GO:0004672 protein kinase activity
1.36 1.73e-03 GO:0000988 protein binding transcription factor activity
1.36 1.73e-03 GO:0000989 transcription factor binding transcription factor activity
1.47 1.73e-03 GO:0004842 ubiquitin-protein ligase activity
1.35 2.37e-03 GO:0003712 transcription cofactor activity
1.25 5.84e-03 GO:0043565 sequence-specific DNA binding
1.42 7.11e-03 GO:0019900 kinase binding
1.30 9.27e-03 GO:0016874 ligase activity
1.29 1.19e-02 GO:0030695 GTPase regulator activity
1.44 1.39e-02 GO:0019901 protein kinase binding
1.39 1.94e-02 GO:0003702 RNA polymerase II transcription factor activity
1.94 2.34e-02 GO:0004722 protein serine/threonine phosphatase activity
1.28 2.41e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.50 2.64e-02 GO:0003714 transcription corepressor activity
1.39 2.71e-02 GO:0016791 phosphatase activity
1.68 4.00e-02 GO:0003729 mRNA binding