Motif ID: TGIF1.p2

Z-value: 0.927


Transcription factors associated with TGIF1.p2:

Gene SymbolEntrez IDGene Name
TGIF1 7050 TGFB-induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TGIF1chr18_+_3449972-0.154.3e-01Click!


Activity profile for motif TGIF1.p2.

activity profile for motif TGIF1.p2


Sorted Z-values histogram for motif TGIF1.p2

Sorted Z-values for motif TGIF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TGIF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_60325073 2.491


chr1_-_24469571 1.994 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr4_+_69313166 1.896 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr1_+_17531619 1.805 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr1_-_152386727 1.753 NM_016190
CRNN
cornulin
chr17_-_39092714 1.495 KRT23
keratin 23 (histone deacetylase inducible)
chr12_+_53442732 1.477 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr9_+_125133322 1.469 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_113594325 1.339 NM_000576
IL1B
interleukin 1, beta
chr22_-_37640187 1.303 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_-_175443601 1.300 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr6_-_41130820 1.273 TREM2
triggering receptor expressed on myeloid cells 2
chr4_-_175443791 1.263 NM_000860
NM_001145816
HPGD

hydroxyprostaglandin dehydrogenase 15-(NAD)

chr1_+_32043745 1.174 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr6_-_41130864 1.122 TREM2
triggering receptor expressed on myeloid cells 2
chr9_+_125133228 1.103 NM_000962
NM_080591
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr9_+_34652125 1.101 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr3_-_189840225 1.100 NM_001134418
LEPREL1
leprecan-like 1
chr16_+_69139466 1.088 NM_001199280
HAS3
hyaluronan synthase 3
chr10_+_102123420 1.076


chr5_+_147691988 1.072 NM_032566
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr17_+_57232859 1.059 NM_018304
PRR11
proline rich 11
chr13_+_78109808 1.053 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr14_-_24732344 1.045 NM_000359
TGM1
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
chr22_-_37640287 1.038 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_-_205391180 1.037 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr1_+_153388999 1.034 NM_176823
S100A7A
S100 calcium binding protein A7A
chr4_+_88896838 1.019 SPP1
secreted phosphoprotein 1
chr3_-_127541975 1.012 NM_001003794
MGLL
monoglyceride lipase
chr17_+_76210329 1.000 BIRC5
baculoviral IAP repeat containing 5
chr4_+_88896801 0.995 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr2_+_27719702 0.988 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr4_+_88896899 0.974 SPP1
secreted phosphoprotein 1
chr4_+_88896868 0.957 SPP1
secreted phosphoprotein 1
chr6_-_41130921 0.949 NM_018965
TREM2
triggering receptor expressed on myeloid cells 2
chrX_-_153775427 0.945 G6PD
glucose-6-phosphate dehydrogenase
chr9_+_116207010 0.930 NM_144488
RGS3
regulator of G-protein signaling 3
chr9_-_72287097 0.893 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr10_+_94352960 0.831 KIF11
kinesin family member 11
chr2_+_239756672 0.828 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr22_+_44395090 0.811 NM_001003828
PARVB
parvin, beta
chr17_+_4402128 0.790 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr12_+_107078476 0.780 NM_032491
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr12_-_117747214 0.776 NM_001204214
NOS1
nitric oxide synthase 1 (neuronal)
chr3_-_127541160 0.773 NM_007283
MGLL
monoglyceride lipase
chr18_+_61420276 0.773 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr2_-_216003068 0.761 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chrX_-_38079980 0.761 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr11_+_129245834 0.757 NM_003658
BARX2
BARX homeobox 2
chr1_+_156252725 0.753 TMEM79
transmembrane protein 79
chr2_+_233925104 0.746 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr1_-_153433104 0.727 NM_002963
S100A7
S100 calcium binding protein A7
chr19_-_36643770 0.727 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr17_-_39728304 0.724 NM_000226
KRT9
keratin 9
chr19_-_14228560 0.723 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr5_-_127873734 0.715 NM_001999
FBN2
fibrillin 2
chr6_+_80714389 0.710 TTK
TTK protein kinase
chr1_+_24645914 0.694 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr6_+_80714321 0.690 NM_001166691
NM_003318
TTK

TTK protein kinase

chr12_+_15475190 0.686 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chrX_+_70443055 0.682 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr17_-_39768939 0.680 NM_005557
KRT16
keratin 16
chr22_-_30234253 0.672 NM_001242906
NM_032204
ASCC2

activating signal cointegrator 1 complex subunit 2

chr17_-_39661803 0.656 NM_002274
NM_153490
KRT13

keratin 13

chr2_+_238536183 0.656 NM_001137550
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr11_-_123756339 0.638 NM_001013743
TMEM225
transmembrane protein 225
chr1_-_150978879 0.637 NM_001163259
NM_001163260
NM_001040217
FAM63A


family with sequence similarity 63, member A


chr17_-_39525873 0.633 NM_002279
KRT33B
keratin 33B
chr1_+_156254069 0.633 NM_032323
TMEM79
transmembrane protein 79
chr2_+_33359607 0.631 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr22_-_50523853 0.629 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_+_233925035 0.625 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr6_-_41863086 0.621 NM_018561
USP49
ubiquitin specific peptidase 49
chr19_-_44285407 0.602 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr12_+_53497287 0.601 SOAT2
sterol O-acyltransferase 2
chr5_-_127873477 0.596 FBN2
fibrillin 2
chr10_-_90750955 0.594 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_-_41934634 0.585 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr14_-_107078578 0.585


chr7_+_139528951 0.582 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr9_-_36276930 0.581 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr4_+_5526882 0.580 NM_005750
C4orf6
chromosome 4 open reading frame 6
chr18_-_67872897 0.579 NM_173630
RTTN
rotatin
chr11_-_74442185 0.578 NM_015424
CHRDL2
chordin-like 2
chr8_-_144654921 0.577 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr9_+_35673852 0.574 NM_001216
CA9
carbonic anhydrase IX
chr4_-_47983430 0.571 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr7_+_77469446 0.569 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr9_+_34990715 0.568 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr19_+_45409003 0.564 NM_000041
APOE
apolipoprotein E
chr13_+_28494136 0.563 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr11_+_842821 0.562 NM_001025238
NM_001025239
NM_003271
NM_001025235
NM_001025236
TSPAN4




tetraspanin 4




chrX_-_153775774 0.552 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr10_+_124220990 0.541 NM_002775
HTRA1
HtrA serine peptidase 1
chr19_-_49865638 0.541 NM_003598
TEAD2
TEA domain family member 2
chr5_-_149682447 0.540 NM_001012301
ARSI
arylsulfatase family, member I
chr11_-_2018568 0.540 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr4_-_143767603 0.537 NM_001101669
NM_003866
INPP4B

inositol polyphosphate-4-phosphatase, type II, 105kDa

chr11_-_568419 0.532 MIR210HG
MIR210 host gene (non-protein coding)
chr1_-_169599349 0.532 NM_003005
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr4_-_114682340 0.529 CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr16_+_71392615 0.527 NM_001740
NM_007088
CALB2

calbindin 2

chr16_-_3030473 0.523 NM_004203
NM_182687
PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

chr16_+_71392637 0.521 CALB2
calbindin 2
chr11_-_119187811 0.521 NM_006500
MCAM
melanoma cell adhesion molecule
chr22_+_31487315 0.520 SMTN
smoothelin
chr1_-_208417635 0.517 NM_025179
PLXNA2
plexin A2
chr19_-_44285012 0.513 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr4_-_156787377 0.512 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chr6_+_24775154 0.510 NM_001251989
NM_001251990
NM_015895
GMNN


geminin, DNA replication inhibitor


chr1_+_6615337 0.504 NM_138697
NM_177540
TAS1R1

taste receptor, type 1, member 1

chr12_+_53497273 0.501 NM_003578
SOAT2
sterol O-acyltransferase 2
chr11_-_64825992 0.499 NM_005468
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr12_+_56325788 0.496 NM_201444
NM_201445
NM_201554
DGKA


diacylglycerol kinase, alpha 80kDa


chr12_+_119616594 0.493 NM_014365
HSPB8
heat shock 22kDa protein 8
chr8_-_125580745 0.489 MTSS1
metastasis suppressor 1
chr3_-_9595412 0.489 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr20_+_20037289 0.484 NM_001167816
C20orf26
chromosome 20 open reading frame 26
chr10_-_88853826 0.478 GLUD1
glutamate dehydrogenase 1
chr4_-_82126200 0.476 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chrX_+_101380659 0.475 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chr16_-_67217403 0.469 KIAA0895L
KIAA0895-like
chr1_+_24645811 0.467 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr14_+_24600674 0.466 NM_203402
FITM1
fat storage-inducing transmembrane protein 1
chr1_+_207002221 0.465 NM_013371
IL19
interleukin 19
chr1_+_74701070 0.463 NM_015978
TNNI3K
TNNI3 interacting kinase
chr19_-_39826676 0.462 NM_004877
GMFG
glia maturation factor, gamma
chr4_+_55095263 0.461 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr22_-_50523737 0.459 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr8_+_28174648 0.459 NM_006228
PNOC
prepronociceptin
chr22_-_50523780 0.458 NM_139202
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_+_46692637 0.457 NM_016426
GTSE1
G-2 and S-phase expressed 1
chr6_+_24775640 0.457 NM_001251991
GMNN
geminin, DNA replication inhibitor
chr7_+_141490016 0.456 NM_018980
TAS2R5
taste receptor, type 2, member 5
chr16_-_67217825 0.453 NM_001040715
KIAA0895L
KIAA0895-like
chr17_+_16945766 0.453 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr2_+_220436953 0.452 NM_002191
INHA
inhibin, alpha
chr4_-_114682594 0.451 CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr5_-_95748688 0.451 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chr1_-_11907741 0.446 NM_006172
NPPA
natriuretic peptide A
chr5_-_112824526 0.445 NM_001085377
MCC
mutated in colorectal cancers
chr7_-_27192201 0.444


chr2_+_33661392 0.443 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr9_-_123639462 0.441 PHF19
PHD finger protein 19
chr2_+_233243243 0.440 NM_001632
ALPP
alkaline phosphatase, placental
chr2_+_211421322 0.439 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr11_+_2924504 0.433 SLC22A18
solute carrier family 22, member 18
chr22_+_25615611 0.432 NM_000496
CRYBB2
crystallin, beta B2
chr5_+_115298136 0.432 NM_173800
AQPEP
laeverin
chr17_-_57232799 0.425 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr4_+_186990308 0.421 NM_003265
TLR3
toll-like receptor 3
chr16_+_69141442 0.418 NM_005329
HAS3
hyaluronan synthase 3
chr9_+_706744 0.412 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr17_+_57233100 0.411 PRR11
proline rich 11
chr17_-_39023461 0.409 NM_000223
KRT12
keratin 12
chr3_-_48632592 0.408 NM_000094
COL7A1
collagen, type VII, alpha 1
chr8_+_38243958 0.407 NM_001199659
NM_144652
LETM2

leucine zipper-EF-hand containing transmembrane protein 2

chr9_+_128510477 0.406 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr17_-_34122547 0.401 NM_001032278
NM_024302
MMP28

matrix metallopeptidase 28

chrX_+_41306686 0.391 NM_022567
NYX
nyctalopin
chr9_+_2622134 0.387 VLDLR
very low density lipoprotein receptor
chr9_-_132805456 0.384 NM_015033
FNBP1
formin binding protein 1
chr4_+_147560042 0.384 NM_004575
POU4F2
POU class 4 homeobox 2
chr20_+_33759773 0.384 NM_006404
PROCR
protein C receptor, endothelial
chr9_+_125132823 0.377 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_-_14372807 0.377 NM_018027
FRMD4A
FERM domain containing 4A
chr10_+_115310589 0.375 NM_001177660
HABP2
hyaluronan binding protein 2
chr22_-_50524357 0.375 NM_015166
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_-_37225360 0.371 NM_145316
TMEM217
transmembrane protein 217
chr9_+_2622099 0.369 VLDLR
very low density lipoprotein receptor
chr15_+_63336274 0.368 TPM1
tropomyosin 1 (alpha)
chr9_+_2622052 0.367 VLDLR
very low density lipoprotein receptor
chr8_-_124408688 0.366 NM_014109
ATAD2
ATPase family, AAA domain containing 2
chr4_-_176923572 0.366 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr4_-_185747051 0.366 ACSL1
acyl-CoA synthetase long-chain family member 1
chr2_+_234668914 0.360 NM_000463
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
chr17_-_7493389 0.355 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr18_+_61144143 0.353 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr14_-_100842637 0.351 WARS
tryptophanyl-tRNA synthetase
chr15_-_42840992 0.349 NM_153260
LRRC57
leucine rich repeat containing 57
chr6_+_151186884 0.347 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr6_-_131384387 0.346 NM_001135554
NM_001135555
NM_001199388
NM_001431
EPB41L2



erythrocyte membrane protein band 4.1-like 2



chr3_+_113251217 0.344 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr17_-_3499124 0.343 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr12_-_53074172 0.341 NM_006121
KRT1
keratin 1
chr7_+_76139744 0.340 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr6_+_31674639 0.340 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr8_-_49833823 0.337 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr17_-_57232524 0.334 SKA2
spindle and kinetochore associated complex subunit 2
chr19_-_11565612 0.331


chr10_+_91498724 0.331 KIF20B
kinesin family member 20B
chr19_-_48547180 0.331 NM_019855
CABP5
calcium binding protein 5
chr7_-_99766191 0.329 GAL3ST4
galactose-3-O-sulfotransferase 4
chr12_+_13043955 0.326 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr20_+_43344005 0.326 WISP2
WNT1 inducible signaling pathway protein 2
chr7_-_99766238 0.325 NM_024637
GAL3ST4
galactose-3-O-sulfotransferase 4
chr13_-_34250899 0.324 NM_001243476
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_119605758 0.322 NM_001426
EN1
engrailed homeobox 1
chr1_-_42384370 0.320 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr19_-_39826625 0.318 GMFG
glia maturation factor, gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 3.35e-05 GO:0023052 signaling
1.31 1.18e-04 GO:0007165 signal transduction
1.26 6.00e-04 GO:0051716 cellular response to stimulus
1.73 1.11e-02 GO:0050878 regulation of body fluid levels
1.09 1.31e-02 GO:0009987 cellular process
1.14 2.14e-02 GO:0065007 biological regulation
1.33 2.17e-02 GO:0065008 regulation of biological quality
1.31 3.56e-02 GO:0048519 negative regulation of biological process
1.16 3.69e-02 GO:0050896 response to stimulus
1.32 3.98e-02 GO:0048523 negative regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 4.21e-05 GO:0005856 cytoskeleton
2.65 1.42e-03 GO:0043292 contractile fiber
2.71 1.51e-03 GO:0030016 myofibril
2.91 7.29e-03 GO:0045095 keratin filament
1.93 7.38e-03 GO:0015629 actin cytoskeleton
2.69 9.66e-03 GO:0030017 sarcomere
2.56 9.74e-03 GO:0044449 contractile fiber part
2.56 1.43e-02 GO:0030055 cell-substrate junction
2.54 2.45e-02 GO:0005924 cell-substrate adherens junction
2.16 2.68e-02 GO:0005882 intermediate filament
2.06 2.83e-02 GO:0045111 intermediate filament cytoskeleton
2.54 3.60e-02 GO:0005925 focal adhesion
2.19 4.71e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.89e-04 GO:0005515 protein binding
1.76 1.34e-03 GO:0008092 cytoskeletal protein binding
4.09 2.38e-03 GO:0008307 structural constituent of muscle
1.92 6.56e-03 GO:0003779 actin binding