Motif ID: UAAUGCU

Z-value: 0.572


Mature miRNA associated with seed UAAUGCU:

NamemiRBase Accession
hsa-miR-155 MIMAT0000646



Activity profile for motif UAAUGCU.

activity profile for motif UAAUGCU


Sorted Z-values histogram for motif UAAUGCU

Sorted Z-values for motif UAAUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAAUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_135502445 0.747 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr20_-_39317875 0.531 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr6_-_56112315 0.521 NM_030820
COL21A1
collagen, type XXI, alpha 1
chr7_+_94285620 0.472 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr7_+_94285676 0.460 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr15_-_89089792 0.408 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr11_-_27721975 0.350 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr17_+_4613780 0.342 NM_004313
NM_199004
ARRB2

arrestin, beta 2

chr11_-_27742224 0.335 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr11_-_27741192 0.333 NM_001143807
BDNF
brain-derived neurotrophic factor
chr17_-_47439326 0.332 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr11_+_111848008 0.331 NM_033425
DIXDC1
DIX domain containing 1
chr1_+_183605207 0.328 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr2_-_233877920 0.327 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr6_-_134373618 0.319 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr11_-_27723061 0.319 NM_170733
BDNF
brain-derived neurotrophic factor
chr18_-_53255734 0.317 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr10_+_83637442 0.315 NM_001165973
NRG3
neuregulin 3
chr11_-_27743604 0.314 NM_170731
BDNF
brain-derived neurotrophic factor
chr11_-_27722599 0.311 NM_001143808
NM_001143809
NM_001143810
NM_001143811
BDNF



brain-derived neurotrophic factor



chr11_-_27722446 0.309 NM_001143812
BDNF
brain-derived neurotrophic factor
chr16_+_5008317 0.302 NM_014692
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr11_-_27721179 0.301 NM_170734
BDNF
brain-derived neurotrophic factor
chr12_+_104458235 0.286 NM_013320
HCFC2
host cell factor C2
chr10_+_83635069 0.280 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr4_-_149363498 0.277 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr18_+_67956136 0.275 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr2_-_217560247 0.267 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr1_+_61547625 0.267 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr11_-_27681195 0.258 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr1_+_61542928 0.251 NM_001145511
NFIA
nuclear factor I/A
chr14_+_31028328 0.248 NM_017769
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr17_+_4981721 0.245 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr12_-_51717905 0.237 NM_016293
BIN2
bridging integrator 2
chr11_+_111807857 0.235 NM_001037954
DIXDC1
DIX domain containing 1
chr1_+_244214552 0.234 NM_205768
ZNF238
zinc finger protein 238
chr11_+_9595183 0.231 NM_003390
WEE1
WEE1 homolog (S. pombe)
chr3_-_123603144 0.229 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr7_-_139876718 0.228 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr16_-_8962842 0.224 NM_014316
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr9_+_119449573 0.222 NM_001099679
NM_012210
TRIM32

tripartite motif containing 32

chr4_+_85504056 0.219 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr16_-_8962247 0.218 NM_001042476
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr11_+_9596233 0.217 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr12_+_72233486 0.211 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr1_+_244216506 0.207 NM_006352
ZNF238
zinc finger protein 238
chr10_+_69644938 0.199 NM_001142498
SIRT1
sirtuin 1
chr17_-_67323185 0.195 NM_172232
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr13_-_37494370 0.192 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr20_+_51588945 0.192 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr6_-_143266283 0.190 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr2_+_61292999 0.189 NM_001129993
KIAA1841
KIAA1841
chr20_+_51801821 0.189 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr15_+_49715374 0.187 NM_002009
FGF7
fibroblast growth factor 7
chr11_-_70507911 0.186 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr17_-_49337370 0.176 NM_017643
MBTD1
mbt domain containing 1
chr10_+_69644341 0.175 NM_012238
SIRT1
sirtuin 1
chr3_-_123339423 0.175 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr12_+_46123495 0.173 NM_152641
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr6_-_80247103 0.172 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr6_+_143999058 0.171 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr6_+_143929316 0.170 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr2_-_233792825 0.170 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr17_-_67311773 0.165 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr6_+_149068148 0.165 NM_005715
UST
uronyl-2-sulfotransferase
chr1_+_61547388 0.164 NM_001145512
NFIA
nuclear factor I/A
chr19_+_1248548 0.161 NM_177401
MIDN
midnolin
chr17_+_35849950 0.157 NM_007026
DUSP14
dual specificity phosphatase 14
chr9_-_15510209 0.156 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr3_+_180630054 0.155 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr5_+_153825497 0.155 NM_001131062
NM_001131063
NM_024632
SAP30L


SAP30-like


chr19_-_31840118 0.150 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr1_-_197169635 0.148 NM_194314
ZBTB41
zinc finger and BTB domain containing 41
chr20_+_11898536 0.147 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr13_+_20532906 0.147 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr9_-_14314036 0.146 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chrX_+_16964730 0.146 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr20_+_48807119 0.145 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr9_-_14398981 0.145 NM_001190738
NFIB
nuclear factor I/B
chr11_-_70935807 0.145 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr7_-_130080823 0.144 NM_018718
CEP41
centrosomal protein 41kDa
chr4_+_129730772 0.142 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr18_-_45456925 0.141 NM_005901
SMAD2
SMAD family member 2
chr22_+_29279573 0.140 NM_001206998
ZNRF3
zinc and ring finger 3
chr10_+_18948276 0.140 NM_178815
ARL5B
ADP-ribosylation factor-like 5B
chr9_-_120177307 0.140 NM_014010
ASTN2
astrotactin 2
chr16_+_70147528 0.138 NM_017990
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr17_-_31203889 0.137 NM_015194
MYO1D
myosin ID
chr17_-_56065596 0.135 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr11_+_35684342 0.134 NM_017583
TRIM44
tripartite motif containing 44
chr15_-_60884615 0.133 NM_134262
RORA
RAR-related orphan receptor A
chr3_+_185000714 0.133 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr13_+_20532788 0.133 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr1_+_60280462 0.133 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr9_+_82186846 0.131 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_-_240322620 0.127 NM_006037
HDAC4
histone deacetylase 4
chr17_-_44302716 0.126 NM_001193465
KIAA1267
KIAA1267
chr18_-_45457454 0.125 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr8_-_57123858 0.125 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr1_-_91487013 0.122 NM_016620
ZNF644
zinc finger protein 644
chr2_+_208394615 0.122 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr17_-_43394326 0.121 NM_003954
MAP3K14
mitogen-activated protein kinase kinase kinase 14
chr10_-_105614952 0.121 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr7_+_29603388 0.120 NM_175887
PRR15
proline rich 15
chr1_+_206643585 0.119 NM_001193321
NM_001193322
NM_014002
IKBKE


inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon


chr1_+_100326765 0.119 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chrX_-_20284708 0.118 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_+_100315631 0.118 NM_000642
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr3_-_18466759 0.116 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr3_-_50608421 0.116 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr5_+_112312392 0.115 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr3_+_120627026 0.115 NM_014980
STXBP5L
syntaxin binding protein 5-like
chr10_-_62703822 0.114 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr20_+_11871364 0.114 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr1_-_202777545 0.113 NM_006618
KDM5B
lysine (K)-specific demethylase 5B
chr10_-_115613858 0.112 NM_014881
DCLRE1A
DNA cross-link repair 1A
chrX_+_55744049 0.111 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr11_+_76156059 0.111 NM_020193
C11orf30
chromosome 11 open reading frame 30
chr1_+_100315806 0.110 NM_000028
NM_000643
NM_000644
AGL


amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase


chr15_+_96869156 0.110 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_-_50605062 0.109 NM_001171740
NM_001171743
NM_016210
C3orf18


chromosome 3 open reading frame 18


chr12_+_124118312 0.108 NM_001516
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
chr14_-_45431121 0.107 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr3_+_23986735 0.106 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr5_-_9546157 0.105 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr15_-_61521478 0.105 NM_134261
RORA
RAR-related orphan receptor A
chrX_-_150067127 0.104 NM_001184808
NM_001242614
NM_031462
NM_134445
NM_134446
CD99L2




CD99 molecule-like 2




chr8_+_67624652 0.104 NM_001033578
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr1_+_33283042 0.104 NM_001017406
NM_022753
S100PBP

S100P binding protein

chrX_-_19988381 0.104 NM_198279
CXorf23
chromosome X open reading frame 23
chr2_-_48132656 0.102 NM_001190274
FBXO11
F-box protein 11
chr3_+_185080835 0.102 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr3_+_23987514 0.101 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr2_-_203736223 0.100 NM_138468
ICA1L
islet cell autoantigen 1,69kDa-like
chr14_-_39901619 0.099 NM_203301
FBXO33
F-box protein 33
chr17_-_44270255 0.098 NM_015443
KIAA1267
KIAA1267
chr14_+_58765209 0.097 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr11_-_72852957 0.097 NM_014824
FCHSD2
FCH and double SH3 domains 2
chr15_-_60919642 0.095 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr15_+_96876568 0.095 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_+_67687415 0.095 NM_013257
NM_170709
SGK3

serum/glucocorticoid regulated kinase family, member 3

chr17_-_44270144 0.095 NM_001193466
KIAA1267
KIAA1267
chr15_+_50716568 0.094 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr2_-_152955502 0.094 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr1_+_204913353 0.091 NM_001160331
NFASC
neurofascin
chr10_+_104503724 0.089 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr17_-_19770988 0.087 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr7_-_112726143 0.085 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr22_+_29313376 0.085 NM_032173
ZNRF3
zinc and ring finger 3
chr8_-_66701175 0.084 NM_002603
PDE7A
phosphodiesterase 7A
chr6_+_34857021 0.084 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr9_-_10612722 0.083 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr2_+_205410465 0.083 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr8_-_103136486 0.083 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
NCALD





neurocalcin delta





chr4_+_38665587 0.082 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr8_-_66753968 0.082 NM_001242318
PDE7A
phosphodiesterase 7A
chr1_+_100316530 0.082 NM_000646
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr8_+_57124314 0.082 NM_001011667
NM_001011668
NM_001011669
NM_001011670
NM_001011671
NM_024300
CHCHD7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr8_-_103137134 0.082 NM_001040630
NCALD
neurocalcin delta
chr8_-_102803438 0.082 NM_032041
NCALD
neurocalcin delta
chr12_-_51477299 0.080 NM_030809
CSRNP2
cysteine-serine-rich nuclear protein 2
chr21_+_30671217 0.080 NM_001186
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr9_-_8733893 0.079 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr3_-_148804122 0.079 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr11_+_121322848 0.078 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_+_227751218 0.078 NM_178549
ZNF678
zinc finger protein 678
chr15_+_89631380 0.078 NM_007011
NM_152924
ABHD2

abhydrolase domain containing 2

chr6_+_28109611 0.077 NM_006298
ZNF192
zinc finger protein 192
chr1_-_155881163 0.077 NM_006912
RIT1
Ras-like without CAAX 1
chr2_-_180129245 0.076 NM_178123
SESTD1
SEC14 and spectrin domains 1
chr4_+_76439653 0.076 NM_144721
THAP6
THAP domain containing 6
chr2_-_152955208 0.076 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr5_+_135468522 0.074 NM_001001419
NM_001001420
NM_005903
SMAD5


SMAD family member 5


chr4_+_30721865 0.074 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr11_-_22647329 0.074 NM_022725
FANCF
Fanconi anemia, complementation group F
chr3_-_18480203 0.074 NM_001131010
SATB1
SATB homeobox 1
chr14_+_74111577 0.073 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr5_-_38595506 0.073 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr1_-_91487769 0.072 NM_032186
NM_201269
ZNF644

zinc finger protein 644

chr16_+_69599868 0.072 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr3_+_38495778 0.072 NM_001106
ACVR2B
activin A receptor, type IIB
chr2_-_48115846 0.071 NM_025133
FBXO11
F-box protein 11
chr5_+_173315313 0.071 NM_030627
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr5_-_38556682 0.071 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr14_+_96968698 0.071 NM_001252006
NM_001252007
NM_032632
PAPOLA


poly(A) polymerase alpha


chr2_-_202316227 0.071 NM_015049
TRAK2
trafficking protein, kinesin binding 2
chr5_-_132073143 0.071 NM_007054
KIF3A
kinesin family member 3A
chr10_+_104535887 0.070 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr12_-_15038724 0.070 NM_000900
NM_001190839
MGP

matrix Gla protein

chr10_-_119805673 0.069 NM_014904
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr1_+_53527723 0.069 NM_001199080
NM_001199082
NM_153703
PODN


podocan


chr1_+_28052467 0.069 NM_001143912
NM_001143913
NM_001143914
NM_001143915
NM_152660
FAM76A




family with sequence similarity 76, member A




chr11_-_85780899 0.068 NM_001206947
PICALM
phosphatidylinositol binding clathrin assembly protein
chr11_-_47400096 0.068 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr7_-_98030426 0.067 NM_018842
BAIAP2L1
BAI1-associated protein 2-like 1
chr17_-_63052884 0.067 NM_006572
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr1_+_53527822 0.067 NM_001199081
PODN
podocan
chr3_-_107809754 0.066 NM_001777
NM_198793
CD47

CD47 molecule

chr2_-_24149899 0.066 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chr12_+_93771607 0.066 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.88 2.11e-06 GO:0010468 regulation of gene expression
1.90 3.46e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.93 8.69e-06 GO:0006355 regulation of transcription, DNA-dependent
1.91 9.38e-06 GO:0051252 regulation of RNA metabolic process
3.75 1.07e-05 GO:0016568 chromatin modification
1.85 1.21e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.69 1.67e-05 GO:0060255 regulation of macromolecule metabolic process
2.89 2.56e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.76 7.96e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76 7.96e-05 GO:0031326 regulation of cellular biosynthetic process
3.16 1.11e-04 GO:0006325 chromatin organization
1.74 1.33e-04 GO:0009889 regulation of biosynthetic process
1.37 1.93e-04 GO:0050794 regulation of cellular process
1.60 2.63e-04 GO:0080090 regulation of primary metabolic process
1.71 3.07e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.58 5.27e-04 GO:0031323 regulation of cellular metabolic process
2.26 1.27e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.50 3.13e-03 GO:0019222 regulation of metabolic process
1.30 5.39e-03 GO:0050789 regulation of biological process
2.52 6.85e-03 GO:0051276 chromosome organization
2.21 9.90e-03 GO:0006351 transcription, DNA-dependent
2.59 1.87e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.26 3.06e-02 GO:0065007 biological regulation
2.40 3.38e-02 GO:0010629 negative regulation of gene expression
36.29 4.14e-02 GO:0034983 peptidyl-lysine deacetylation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.58 5.14e-10 GO:0005634 nucleus
2.09 2.25e-07 GO:0031981 nuclear lumen
1.91 2.02e-06 GO:0044428 nuclear part
1.21 2.24e-05 GO:0044424 intracellular part
1.20 2.38e-05 GO:0005622 intracellular
2.13 2.56e-05 GO:0005654 nucleoplasm
2.57 5.50e-05 GO:0044451 nucleoplasm part
1.76 1.11e-04 GO:0043233 organelle lumen
1.27 1.38e-04 GO:0043231 intracellular membrane-bounded organelle
1.27 1.52e-04 GO:0043227 membrane-bounded organelle
1.75 2.09e-04 GO:0070013 intracellular organelle lumen
1.73 2.13e-04 GO:0031974 membrane-enclosed lumen
1.23 3.59e-04 GO:0043229 intracellular organelle
1.23 4.26e-04 GO:0043226 organelle
3.39 3.05e-03 GO:0005667 transcription factor complex
6.05 3.41e-02 GO:0016605 PML body

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.07 9.50e-10 GO:0003677 DNA binding
2.66 5.00e-08 GO:0001071 nucleic acid binding transcription factor activity
2.66 5.00e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.75 1.12e-07 GO:0003676 nucleic acid binding
1.20 1.01e-05 GO:0005488 binding
1.84 4.90e-05 GO:0008270 zinc ion binding
38.71 2.56e-04 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
1.30 1.07e-03 GO:0005515 protein binding
1.67 1.61e-03 GO:0046914 transition metal ion binding
5.33 2.04e-03 GO:0005057 receptor signaling protein activity
1.46 2.61e-03 GO:0043167 ion binding
2.34 3.50e-03 GO:0043565 sequence-specific DNA binding
1.45 3.98e-03 GO:0043169 cation binding
1.45 4.05e-03 GO:0046872 metal ion binding
19.36 9.88e-03 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
6.92 1.80e-02 GO:0004702 receptor signaling protein serine/threonine kinase activity
1.93 2.43e-02 GO:0030528 transcription regulator activity