Motif ID: UUGGCAA

Z-value: 1.035


Mature miRNA associated with seed UUGGCAA:

NamemiRBase Accession
hsa-miR-182 MIMAT0000259



Activity profile for motif UUGGCAA.

activity profile for motif UUGGCAA


Sorted Z-values histogram for motif UUGGCAA

Sorted Z-values for motif UUGGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_52580805 6.517 NM_001080430
TOX3
TOX high mobility group box family member 3
chr16_-_52581713 6.225 NM_001146188
TOX3
TOX high mobility group box family member 3
chr7_-_131241321 4.166 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr2_-_99771186 4.101 NM_025244
TSGA10
testis specific, 10
chr20_+_9049660 4.076 NM_001172646
PLCB4
phospholipase C, beta 4
chr2_-_99758034 4.040 NM_182911
TSGA10
testis specific, 10
chr6_-_10838712 3.892 NM_001242385
NM_001242957
NM_005906
MAK


male germ cell-associated kinase


chr20_+_9288446 3.841 NM_000933
PLCB4
phospholipase C, beta 4
chr7_-_158380360 3.726 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr6_+_135502445 3.693 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr5_-_16509106 3.636 NM_019000
FAM134B
family with sequence similarity 134, member B
chr20_+_9198036 3.591 NM_182797
PLCB4
phospholipase C, beta 4
chr13_+_24734788 3.381 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr11_+_111848008 3.305 NM_033425
DIXDC1
DIX domain containing 1
chr3_-_9994057 3.224 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr2_-_86564632 2.949 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr3_+_186739643 2.932 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr8_+_17354562 2.898 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr5_-_16617085 2.842 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr2_-_86565205 2.806 NM_001164730
REEP1
receptor accessory protein 1
chr3_+_186648273 2.764 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr19_+_32897021 2.541 NM_207325
DPY19L3
dpy-19-like 3 (C. elegans)
chr20_+_51588945 2.515 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr5_+_50678957 2.482 NM_002202
ISL1
ISL LIM homeobox 1
chr19_+_32896515 2.430 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr12_-_94853696 2.428 NM_001042399
NM_016122
CCDC41

coiled-coil domain containing 41

chr19_-_14316980 2.417 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr20_+_51801821 2.360 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr8_+_17396285 2.336 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr14_-_90085325 2.298 NM_001085471
FOXN3
forkhead box N3
chr7_+_114055048 2.208 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr2_+_85980600 2.179 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr1_-_217262946 2.140 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr8_-_103136486 2.139 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
NCALD





neurocalcin delta





chr2_+_97481977 2.126 NM_017623
NM_199078
CNNM3

cyclin M3

chr11_+_111807857 2.125 NM_001037954
DIXDC1
DIX domain containing 1
chr1_+_3607232 2.115 NM_001126240
NM_001126241
NM_001126242
NM_001204189
NM_001204190
NM_001204191
TP73





tumor protein p73





chr1_+_3569098 2.099 NM_001204184
NM_001204185
NM_001204186
NM_001204187
NM_001204188
NM_005427
TP73





tumor protein p73





chr8_-_103137134 2.070 NM_001040630
NCALD
neurocalcin delta
chrX_+_16964730 2.039 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr17_+_68165660 2.035 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_+_3614609 2.031 NM_001204192
TP73
tumor protein p73
chr14_-_89883306 2.031 NM_005197
FOXN3
forkhead box N3
chr10_-_62703822 2.008 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr1_-_217311095 2.002 NM_001134285
ESRRG
estrogen-related receptor gamma
chr1_-_216896640 1.929 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr8_-_102803438 1.926 NM_032041
NCALD
neurocalcin delta
chr3_+_238274 1.871 NM_001253387
NM_006614
CHL1

cell adhesion molecule with homology to L1CAM (close homolog of L1)

chr7_-_130080823 1.870 NM_018718
CEP41
centrosomal protein 41kDa
chr15_-_49255640 1.824 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chrX_+_9431314 1.802 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr6_+_138483024 1.777 NM_020340
KIAA1244
KIAA1244
chr11_+_46299161 1.735 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr1_-_86043932 1.687 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_-_85930733 1.660 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr14_+_74111577 1.647 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr4_+_95679075 1.637 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr9_+_131217433 1.635 NM_153436
ODF2
outer dense fiber of sperm tails 2
chr9_+_131219185 1.613 NM_153437
ODF2
outer dense fiber of sperm tails 2
chr3_+_179370779 1.599 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr10_+_124768401 1.549 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr8_+_120885899 1.528 NM_022783
DEPTOR
DEP domain containing MTOR-interacting protein
chr19_-_33555757 1.488 NM_033103
RHPN2
rhophilin, Rho GTPase binding protein 2
chr9_-_139922705 1.487 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr7_+_30174343 1.484 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr2_-_213403280 1.478 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr2_-_62733475 1.470 NM_198276
TMEM17
transmembrane protein 17
chr6_+_1312674 1.464 NM_033260
FOXQ1
forkhead box Q1
chr1_-_227505796 1.458 NM_003607
NM_014826
CDC42BPA

CDC42 binding protein kinase alpha (DMPK-like)

chrX_+_9432980 1.455 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr9_+_131218678 1.444 NM_153433
NM_153440
ODF2

outer dense fiber of sperm tails 2

chr3_-_161089747 1.425 NM_001040100
SPTSSB
serine palmitoyltransferase, small subunit B
chr5_+_153825497 1.419 NM_001131062
NM_001131063
NM_024632
SAP30L


SAP30-like


chr3_+_14444083 1.418 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr11_+_76777926 1.386 NM_004055
CAPN5
calpain 5
chr17_+_72322350 1.380 NM_153209
KIF19
kinesin family member 19
chr3_+_69812961 1.364 NM_006722
MITF
microphthalmia-associated transcription factor
chr6_-_109762373 1.360 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr12_+_110906203 1.338 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr21_-_34852282 1.337 NM_006134
TMEM50B
transmembrane protein 50B
chr3_-_37034609 1.298 NM_014805
EPM2AIP1
EPM2A (laforin) interacting protein 1
chrY_+_16634487 1.290 NM_001206850
NLGN4Y
neuroligin 4, Y-linked
chr16_+_14164879 1.266 NM_014048
MKL2
MKL/myocardin-like 2
chr9_-_139923214 1.229 NM_212533
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_-_234614848 1.213 NM_005646
TARBP1
TAR (HIV-1) RNA binding protein 1
chr6_+_36164528 1.203 NM_015695
BRPF3
bromodomain and PHD finger containing, 3
chr2_+_54952148 1.199 NM_001039753
EML6
echinoderm microtubule associated protein like 6
chr5_+_127419407 1.190 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr10_+_72163860 1.185 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr6_-_79787939 1.161 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr3_+_69915374 1.158 NM_198177
MITF
microphthalmia-associated transcription factor
chr4_+_75858205 1.151 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr3_+_69788562 1.143 NM_198159
MITF
microphthalmia-associated transcription factor
chr9_+_131218279 1.139 NM_001242352
NM_001242353
NM_001242354
NM_002540
NM_153432
NM_153435
NM_153439
ODF2






outer dense fiber of sperm tails 2






chr20_-_21494663 1.134 NM_002509
NKX2-2
NK2 homeobox 2
chr3_+_23986735 1.126 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chrX_-_106449543 1.124 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr14_-_39901619 1.118 NM_203301
FBXO33
F-box protein 33
chr12_-_56652118 1.100 NM_173595
ANKRD52
ankyrin repeat domain 52
chr3_+_69812620 1.098 NM_001184967
MITF
microphthalmia-associated transcription factor
chr3_+_23987514 1.096 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr2_-_152955502 1.095 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr2_+_61292999 1.083 NM_001129993
KIAA1841
KIAA1841
chr7_+_17338182 1.080 NM_001621
AHR
aryl hydrocarbon receptor
chr16_-_19896105 1.069 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr1_+_109656570 1.066 NM_020775
KIAA1324
KIAA1324
chr8_-_93978264 1.055 NM_001191035
NM_001171795
NM_001171796
NM_001171797
NM_001171798
NM_001171799
C8orf83





chromosome 8 open reading frame 83





chrX_+_77166178 1.037 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr1_+_57110745 1.029 NM_006252
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr14_-_65438794 1.028 NM_198686
RAB15
RAB15, member RAS onocogene family
chr14_+_64682671 1.023 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr2_+_45878912 1.018 NM_005400
PRKCE
protein kinase C, epsilon
chrX_+_17393537 1.016 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_-_152955208 1.015 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr22_-_44893903 1.013 NM_032287
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr9_+_115983807 1.004 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chrX_+_17653412 0.991 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr14_+_105331581 0.981 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr3_-_133614421 0.972 NM_016577
RAB6B
RAB6B, member RAS oncogene family
chr2_-_44587812 0.969 NM_006036
PREPL
prolyl endopeptidase-like
chr3_-_46037299 0.962 NM_024513
FYCO1
FYVE and coiled-coil domain containing 1
chr5_-_179498995 0.956 NM_018434
RNF130
ring finger protein 130
chr6_-_80247103 0.952 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr6_+_80340971 0.950 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr10_+_104613966 0.935 NM_001136200
NM_144591
C10orf32-AS3MT
C10orf32

C10orf32-AS3MT readthrough
chromosome 10 open reading frame 32

chr5_-_9546157 0.929 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chrY_+_16635625 0.921 NM_014893
NLGN4Y
neuroligin 4, Y-linked
chr9_+_976963 0.917 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr17_-_1532109 0.914 NM_152346
SLC43A2
solute carrier family 43, member 2
chr5_+_131705353 0.905 NM_003060
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr3_+_181429711 0.905 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr10_-_62149487 0.895 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_61900659 0.894 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_25164902 0.889 NM_018947
CYCS
cytochrome c, somatic
chr2_-_44586854 0.879 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr7_-_112726143 0.877 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chrX_-_34675366 0.864 NM_031442
TMEM47
transmembrane protein 47
chr5_-_90679115 0.862 NM_020801
ARRDC3
arrestin domain containing 3
chr19_-_33793429 0.862 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chrX_+_72782961 0.861 NM_001039840
CHIC1
cysteine-rich hydrophobic domain 1
chr10_-_116418056 0.860 NM_002313
ABLIM1
actin binding LIM protein 1
chr14_-_81405883 0.853 NM_152446
CEP128
centrosomal protein 128kDa
chr20_+_278200 0.849 NM_033089
ZCCHC3
zinc finger, CCHC domain containing 3
chr10_-_116444374 0.844 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr10_-_62332666 0.836 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_+_64680858 0.834 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr9_+_119449573 0.830 NM_001099679
NM_012210
TRIM32

tripartite motif containing 32

chr7_-_47621741 0.826 NM_022748
TNS3
tensin 3
chr2_-_158731622 0.822 NM_001105
ACVR1
activin A receptor, type I
chr18_-_47721165 0.818 NM_001080467
MYO5B
myosin VB
chr22_-_39548448 0.817 NM_175709
CBX7
chromobox homolog 7
chr10_-_62493282 0.814 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr8_+_28351694 0.813 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr8_+_101170510 0.810 NM_003114
SPAG1
sperm associated antigen 1
chr13_+_115079943 0.809 NM_001164144
NM_001164145
NM_032436
CHAMP1


chromosome alignment maintaining phosphoprotein 1


chr8_+_110346549 0.798 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr12_+_52345437 0.797 NM_004302
NM_020328
ACVR1B

activin A receptor, type IB

chr14_+_58765209 0.794 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr9_-_80646150 0.794 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr8_+_101170231 0.790 NM_172218
SPAG1
sperm associated antigen 1
chr10_-_116286661 0.780 NM_006720
ABLIM1
actin binding LIM protein 1
chr2_-_152830448 0.778 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr11_-_79151694 0.773 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chrX_+_70752911 0.768 NM_181672
NM_181673
OGT

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr7_-_95225802 0.768 NM_002612
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr14_+_56046796 0.766 NM_001079521
NM_001079522
NM_004986
NM_182926
KTN1



kinectin 1 (kinesin receptor)



chr12_-_106533810 0.763 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr10_-_61469322 0.760 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr17_-_27621163 0.757 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr6_+_52285804 0.754 NM_001172420
EFHC1
EF-hand domain (C-terminal) containing 1
chr9_+_79056581 0.751 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr4_-_88141614 0.745 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr7_+_94536926 0.740 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr9_+_71320105 0.736 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr9_-_79520878 0.735 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr4_+_108745718 0.732 NM_001136258
SGMS2
sphingomyelin synthase 2
chr10_+_92980322 0.726 NM_032373
PCGF5
polycomb group ring finger 5
chr20_-_50384899 0.725 NM_006045
ATP9A
ATPase, class II, type 9A
chr4_-_16228097 0.718 NM_153365
TAPT1
transmembrane anterior posterior transformation 1
chr7_+_43966007 0.713 NM_015983
UBE2D4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr2_+_39103102 0.710 NM_001145450
MORN2
MORN repeat containing 2
chr7_-_112727832 0.704 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr3_+_69985750 0.703 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr1_-_202858225 0.700 NM_002871
RABIF
RAB interacting factor
chr9_+_4490193 0.699 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr4_+_108814419 0.698 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr2_-_218808705 0.695 NM_022648
TNS1
tensin 1
chr6_+_30295007 0.688 NM_172016
TRIM39
tripartite motif containing 39
chr2_-_158732341 0.682 NM_001111067
ACVR1
activin A receptor, type I
chr4_-_37687932 0.679 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr2_-_174828775 0.675 NM_001017371
SP3
Sp3 transcription factor
chr6_+_18155535 0.664 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr8_+_92082423 0.662 NM_016023
OTUD6B
OTU domain containing 6B
chr17_+_61699786 0.661 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr2_-_68479481 0.657 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr2_-_96931744 0.651 NM_001193304
NM_017849
TMEM127

transmembrane protein 127

chr6_-_90121966 0.644 NM_021244
RRAGD
Ras-related GTP binding D
chr5_+_67511578 0.637 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr2_+_32288579 0.637 NM_014946
NM_199436
SPAST

spastin

chr12_-_56727446 0.637 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.68 4.79e-05 GO:0006464 protein modification process
1.62 2.34e-04 GO:0043412 macromolecule modification
1.33 4.36e-03 GO:0044260 cellular macromolecule metabolic process
1.90 1.53e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.44 1.64e-02 GO:0044267 cellular protein metabolic process
1.96 2.68e-02 GO:0045893 positive regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.02 1.57e-04 GO:0044451 nucleoplasm part
1.47 3.15e-03 GO:0044428 nuclear part
1.52 3.36e-03 GO:0031981 nuclear lumen
1.62 4.29e-03 GO:0005654 nucleoplasm
1.11 7.77e-03 GO:0005622 intracellular
1.24 1.06e-02 GO:0005634 nucleus
1.12 1.22e-02 GO:0044424 intracellular part
1.13 4.78e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.90 3.21e-02 GO:0046332 SMAD binding
9.41 4.87e-02 GO:0032452 histone demethylase activity