• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: YY1.p2

Z-value: 2.047

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_211751953	3.145		SLC30A1	solute carrier family 30 (zinc transporter), member 1
chr13_+_96204941	2.594	NM_006984	CLDN10	claudin 10
chr17_+_26369935	2.362		NLK	nemo-like kinase
chr3_-_197676755	2.033	NM_001134435	IQCG	IQ motif containing G
chr2_-_216241321	1.994		FN1	fibronectin 1
chr5_-_1494872	1.792		LPCAT1	lysophosphatidylcholine acyltransferase 1
chr3_+_133494275	1.761		TF	transferrin
chr17_+_26369617	1.579	NM_016231	NLK	nemo-like kinase
chr10_+_94833646	1.520	NM_000783	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1
chr1_-_149858114	1.443	NM_003528	HIST2H2BE	histone cluster 2, H2be
chr1_-_211752052	1.387	NM_021194	SLC30A1	solute carrier family 30 (zinc transporter), member 1
chr19_-_5622794	1.347	NM_014649	SAFB2	scaffold attachment factor B2
chr10_-_61666184	1.321		CCDC6	coiled-coil domain containing 6
chr6_+_33168602	1.288	NM_001077516 NM_006979	SLC39A7	solute carrier family 39 (zinc transporter), member 7
chr17_+_7487125	1.257		MPDU1	mannose-P-dolichol utilization defect 1
chr20_-_21378046	1.226	NM_033176	NKX2-4	NK2 homeobox 4
chr2_+_149402559	1.173	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr9_-_89562103	1.146	NM_002048	GAS1	growth arrest-specific 1
chr5_-_158635080	1.139	NM_001199381	RNF145	ring finger protein 145
chr16_-_87903028	1.131	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr5_-_158634641	1.122	NM_001199382	RNF145	ring finger protein 145
chr6_+_26217145	1.083	NM_021052	HIST1H2AE	histone cluster 1, H2ae
chr6_-_26216871	1.053	NM_003518	HIST1H2BG NCALD	histone cluster 1, H2bg neurocalcin delta
chr2_+_149402321	1.036		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr5_-_158634833	1.022	NM_144726	RNF145	ring finger protein 145
chr12_+_102091399	1.021	NM_020244	CHPT1	choline phosphotransferase 1
chr6_-_29595746	1.010		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr19_-_13044459	0.994		FARSA	phenylalanyl-tRNA synthetase, alpha subunit
chr5_-_158636489	0.989	NM_001199383	RNF145	ring finger protein 145
chr8_-_110655418	0.967	NM_001099756	SYBU	syntabulin (syntaxin-interacting)
chr17_+_14204326	0.960	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_-_29527701	0.954	NM_006398	UBD	ubiquitin D
chr15_-_52587851	0.941	NM_018728	MYO5C	myosin VC
chr5_+_148206155	0.936	NM_000024	ADRB2	adrenergic, beta-2-, receptor, surface
chr7_+_106685007	0.934	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr15_-_75248925	0.934		RPP25	ribonuclease P/MRP 25kDa subunit
chr22_-_36013303	0.933	NM_005368 NM_203378	MB	myoglobin
chr19_-_41903226	0.924	NM_020158	EXOSC5	exosome component 5
chr19_-_13044528	0.922	NM_004461	FARSA	phenylalanyl-tRNA synthetase, alpha subunit
chr20_-_3765747	0.915		CENPB	centromere protein B, 80kDa
chr3_-_179322410	0.892	NM_020409 NM_177988	MRPL47	mitochondrial ribosomal protein L47
chr8_+_40010986	0.883	NM_020130	C8orf4	chromosome 8 open reading frame 4
chr19_-_13044524	0.878		FARSA	phenylalanyl-tRNA synthetase, alpha subunit
chr12_-_120554558	0.865		RAB35	RAB35, member RAS oncogene family
chr14_-_50583194	0.862	NM_001040662 NM_024558	METTL21D	methyltransferase like 21D
chr1_+_231114839	0.856
chr17_-_61904262	0.848		FTSJ3	FtsJ homolog 3 (E. coli)
chr1_-_154193044	0.837		C1orf43	chromosome 1 open reading frame 43
chr6_-_47254143	0.836		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr10_+_105005643	0.834	NM_001143909	LOC729020	rcRPE
chr1_-_44820939	0.831		ERI3	ERI1 exoribonuclease family member 3
chr19_-_5622725	0.830		SAFB2	scaffold attachment factor B2
chr13_-_20357125	0.827	NM_001042414	PSPC1	paraspeckle component 1
chr10_-_123353330	0.825	NM_001144913 NM_001144914	FGFR2	fibroblast growth factor receptor 2
chr17_+_7486964	0.824	NM_004870	MPDU1	mannose-P-dolichol utilization defect 1
chr6_-_26271588	0.821	NM_003534	HIST1H3G	histone cluster 1, H3g
chr16_+_57406398	0.820	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr6_+_36562089	0.810	NM_003017	SRSF3	serine/arginine-rich splicing factor 3
chr12_-_105322056	0.805	NM_032148	SLC41A2	solute carrier family 41, member 2
chr10_-_123353771	0.801	NM_001144916	FGFR2	fibroblast growth factor receptor 2
chr1_+_46049659	0.796	NM_001195193 NM_002482 NM_152298	NASP	nuclear autoantigenic sperm protein (histone-binding)
chr17_-_1531543	0.787		SLC43A2	solute carrier family 43, member 2
chr1_-_44820923	0.785		ERI3	ERI1 exoribonuclease family member 3
chr11_+_6411637	0.773	NM_000543 NM_001007593	SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal
chr1_-_200377488	0.773		ZNF281	zinc finger protein 281
chr1_+_101361649	0.770		SLC30A7	solute carrier family 30 (zinc transporter), member 7
chr1_+_161195832	0.766	NM_032174	TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr15_-_77363519	0.751	NM_001168412 NM_005724 NM_198902	TSPAN3	tetraspanin 3
chr4_+_75858205	0.748	NM_015393	PARM1	prostate androgen-regulated mucin-like protein 1
chr6_-_29527477	0.733		UBD	ubiquitin D
chr11_-_34937831	0.722	NM_015957	APIP	APAF1 interacting protein
chr1_-_44820935	0.717	NM_024066	ERI3	ERI1 exoribonuclease family member 3
chr12_-_108954942	0.717		SART3	squamous cell carcinoma antigen recognized by T cells 3
chr9_-_130497617	0.712	NM_001085347 NM_001134430 NM_001134431 NM_001252018 NM_001252021 NM_001252023 NM_130459	TOR2A	torsin family 2, member A
chr2_-_164592512	0.709	NM_018086	FIGN	fidgetin
chr12_-_108954952	0.708		SART3	squamous cell carcinoma antigen recognized by T cells 3
chr2_+_236403290	0.702		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_-_60780404	0.700	NM_018014 NM_022893 NM_138559	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr2_+_68384986	0.697	NM_020143	PNO1	partner of NOB1 homolog (S. cerevisiae)
chr5_-_149669187	0.694		CAMK2A	calcium/calmodulin-dependent protein kinase II alpha
chr6_+_21593963	0.691	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr9_-_130497551	0.686		TOR2A	torsin family 2, member A
chr19_-_50380451	0.681	NM_032375 NM_001098633 NM_001098632	AKT1S1	AKT1 substrate 1 (proline-rich)
chr19_-_50413063	0.659		NUP62	nucleoporin 62kDa
chr1_+_154192654	0.656	NM_001127320	UBAP2L	ubiquitin associated protein 2-like
chr11_+_109964086	0.655	NM_033390	ZC3H12C	zinc finger CCCH-type containing 12C
chr5_+_156820161	0.651		CYFIP2	cytoplasmic FMR1 interacting protein 2
chr11_-_9225780	0.648		DENND5A	DENN/MADD domain containing 5A
chr20_+_42086533	0.644		SRSF6	serine/arginine-rich splicing factor 6
chr3_-_128840343	0.640		RAB43	RAB43, member RAS oncogene family
chr19_+_46850245	0.640	NM_001204284 NM_006247	PPP5C	protein phosphatase 5, catalytic subunit
chr11_+_101918168	0.632	NM_001195005 NM_032930	C11orf70	chromosome 11 open reading frame 70
chr6_-_47253962	0.629		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr2_+_183989082	0.629	NM_138285	NUP35	nucleoporin 35kDa
chr1_-_117753476	0.629	NM_001253850 NM_024626	VTCN1	V-set domain containing T cell activation inhibitor 1
chr19_+_49376488	0.625		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr19_+_507475	0.623	NM_033513	TPGS1	tubulin polyglutamylase complex subunit 1
chr1_+_164528914	0.622		PBX1	pre-B-cell leukemia homeobox 1
chr14_-_21852085	0.622		SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)
chr21_+_34922923	0.621		SON	SON DNA binding protein
chr12_-_49392909	0.619	NM_015086	DDN	dendrin
chr10_-_14816895	0.608	NM_031453	FAM107B	family with sequence similarity 107, member B
chr7_-_111846384	0.607	NM_014705	DOCK4	dedicator of cytokinesis 4
chr10_-_129691202	0.605	NM_152311	CLRN3	clarin 3
chr6_-_82461857	0.604		FAM46A	family with sequence similarity 46, member A
chr2_+_236402948	0.602		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr3_-_190040192	0.597	NM_021101	CLDN1	claudin 1
chr16_-_30621628	0.596	NM_138447	ZNF689	zinc finger protein 689
chr2_+_135676409	0.596		CCNT2	cyclin T2
chr20_-_34243118	0.593		RBM12	RNA binding motif protein 12
chr19_+_35630391	0.593	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr13_-_20356788	0.592		PSPC1	paraspeckle component 1
chr2_+_178257371	0.591	NM_003659	AGPS	alkylglycerone phosphate synthase
chr5_+_131409484	0.591	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr5_-_79950783	0.591	NM_000791	DHFR	dihydrofolate reductase
chr14_-_21852161	0.590		SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)
chr1_+_107599266	0.589	NM_018137	PRMT6	protein arginine methyltransferase 6
chr6_+_27775898	0.589	NM_003509	HIST1H2AI HIST1H2AM HIST1H3F	histone cluster 1, H2ai histone cluster 1, H2am histone cluster 1, H3f
chr12_-_50222144	0.586	NM_001037806	NCKAP5L	NCK-associated protein 5-like
chr1_+_16693582	0.583	NM_001114600 NM_015609	C1orf144	chromosome 1 open reading frame 144
chr1_+_101361688	0.578		SLC30A7	solute carrier family 30 (zinc transporter), member 7
chr13_-_20357043	0.576		PSPC1	paraspeckle component 1
chr6_-_31745048	0.574	NM_025258	C6orf27	chromosome 6 open reading frame 27
chr6_-_46825942	0.573		GPR116	G protein-coupled receptor 116
chr13_-_26625164	0.573	NM_001007538	SHISA2	shisa homolog 2 (Xenopus laevis)
chr11_-_116968986	0.570	NM_025164	SIK3	SIK family kinase 3
chr1_+_110577219	0.566	NM_033088	FAM40A	family with sequence similarity 40, member A
chr1_-_232651227	0.566	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr1_+_101361589	0.565	NM_001144884 NM_133496	SLC30A7	solute carrier family 30 (zinc transporter), member 7
chr1_+_110577248	0.562		FAM40A	family with sequence similarity 40, member A
chr1_+_87797371	0.562		LMO4	LIM domain only 4
chr3_+_47866474	0.562		DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr1_+_110577241	0.562		FAM40A	family with sequence similarity 40, member A
chr14_-_55369163	0.558	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr3_-_23958396	0.558		NKIRAS1	NFKB inhibitor interacting Ras-like 1
chr9_-_34397786	0.555	NM_032596	C9orf24	chromosome 9 open reading frame 24
chr13_-_31735718	0.554		HSPH1	heat shock 105kDa/110kDa protein 1
chr6_-_132939208	0.554	NM_014626	TAAR2	trace amine associated receptor 2
chr1_-_200377262	0.551		ZNF281	zinc finger protein 281
chr6_+_135502521	0.546		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr3_-_23958500	0.545	NM_020345	NKIRAS1	NFKB inhibitor interacting Ras-like 1
chr9_+_129724503	0.545	NM_001190728	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1
chr1_-_211848820	0.544	NM_001204182 NM_001204183 NM_002497	NEK2	NIMA (never in mitosis gene a)-related kinase 2
chr10_+_14880137	0.542	NM_016299	HSPA14	heat shock 70kDa protein 14
chr7_+_114055048	0.542	NM_001172766 NM_014491 NM_148898 NM_148900	FOXP2	forkhead box P2
chr15_+_74218962	0.542		LOXL1	lysyl oxidase-like 1
chr6_-_31509769	0.540		DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr1_+_161719540	0.539	NM_007240	DUSP12	dual specificity phosphatase 12
chr8_-_121824015	0.538
chr9_-_86322593	0.537		UBQLN1	ubiquilin 1
chr1_+_6268919	0.533		RNF207	ring finger protein 207
chr1_+_11333502	0.532		UBIAD1	UbiA prenyltransferase domain containing 1
chr20_+_10415949	0.532	NM_001009608	C20orf94	chromosome 20 open reading frame 94
chr18_-_52988916	0.531	NM_001243234 NM_001243235	TCF4	transcription factor 4
chr1_-_44820700	0.531		ERI3	ERI1 exoribonuclease family member 3
chr4_-_83295136	0.531	NM_001003810 NM_002138 NM_031369 NM_031370	HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr17_+_20108298	0.528		SPECC1	sperm antigen with calponin homology and coiled-coil domains 1
chr12_-_108954929	0.528		SART3	squamous cell carcinoma antigen recognized by T cells 3
chrX_-_153236621	0.527	NM_005334	HCFC1	host cell factor C1 (VP16-accessory protein)
chr11_+_72525352	0.526	NM_033388	ATG16L2	ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr20_+_48429375	0.524		SLC9A8	solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr3_-_48229328	0.524		CDC25A	cell division cycle 25 homolog A (S. pombe)
chr20_+_42086468	0.521	NM_006275	SRSF6	serine/arginine-rich splicing factor 6
chr14_-_21270537	0.521	NM_198232	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)
chr12_-_108955164	0.517	NM_014706	SART3	squamous cell carcinoma antigen recognized by T cells 3
chr5_-_172755195	0.517		STC2	stanniocalcin 2
chr20_-_34329872	0.516		RBM39	RNA binding motif protein 39
chr16_+_3019466	0.508		PAQR4	progestin and adipoQ receptor family member IV
chr8_+_9953061	0.508	NM_001135671 NM_001199729	MSRA	methionine sulfoxide reductase A
chr1_+_36023389	0.508	NM_001014839 NM_001014841 NM_014284	NCDN	neurochondrin
chr1_-_11120001	0.507		SRM	spermidine synthase
chr5_+_70944968	0.507		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr14_-_20774129	0.506	NM_138376	TTC5	tetratricopeptide repeat domain 5
chr17_+_45908992	0.505	NM_033413	LRRC46	leucine rich repeat containing 46
chr17_-_27621076	0.504		NUFIP2	nuclear fragile X mental retardation protein interacting protein 2
chr11_+_111385509	0.503	NM_001100388 NM_207430	C11orf88	chromosome 11 open reading frame 88
chr12_+_8234796	0.502	NM_015509	NECAP1	NECAP endocytosis associated 1
chr1_+_224301790	0.501	NM_001136115 NM_015176	FBXO28	F-box protein 28
chr2_-_128283845	0.498	NM_017969	IWS1	IWS1 homolog (S. cerevisiae)
chr20_-_34330179	0.494	NM_001242599 NM_001242600 NM_004902 NM_184234	RBM39	RNA binding motif protein 39
chr3_+_49449753	0.493		TCTA	T-cell leukemia translocation altered gene
chr13_-_107187312	0.493	NM_004093	EFNB2	ephrin-B2
chr1_+_11333244	0.493	NM_013319	UBIAD1	UbiA prenyltransferase domain containing 1
chr10_-_53459309	0.492	NM_015235	CSTF2T	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr3_-_185655648	0.490		TRA2B	transformer 2 beta homolog (Drosophila)
chr3_+_128199744	0.489
chr17_+_42634598	0.489	NM_001466	FZD2	frizzled family receptor 2
chr16_+_67226098	0.488		E2F4	E2F transcription factor 4, p107/p130-binding
chr7_+_116660291	0.488		ST7	suppression of tumorigenicity 7
chr7_+_150065968	0.486		REPIN1	replication initiator 1
chr12_-_49960221	0.485	NM_001012300	MCRS1	microspherule protein 1
chr9_-_131709783	0.482	NM_014908	DOLK	dolichol kinase
chr13_-_21476849	0.482		XPO4	exportin 4
chr17_-_76719671	0.480		CYTH1	cytohesin 1
chr6_+_43484776	0.479	NM_203290	POLR1C	polymerase (RNA) I polypeptide C, 30kDa
chr1_+_38022514	0.479	NM_003462	DNALI1	dynein, axonemal, light intermediate chain 1
chr4_-_83294806	0.479		HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr6_+_36562139	0.478		SRSF3	serine/arginine-rich splicing factor 3
chrX_+_70752911	0.477	NM_181672 NM_181673	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr11_-_124670283	0.476	NM_024631	C11orf61	chromosome 11 open reading frame 61

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.28	6.18e-36	GO:0044260	cellular macromolecule metabolic process
1.20	3.71e-31	GO:0044237	cellular metabolic process
1.22	3.62e-25	GO:0043170	macromolecule metabolic process
1.40	2.26e-24	GO:0010467	gene expression
1.41	2.63e-23	GO:0016070	RNA metabolic process
1.70	2.83e-23	GO:0006396	RNA processing
1.35	5.97e-23	GO:0090304	nucleic acid metabolic process
1.09	6.41e-23	GO:0009987	cellular process
1.74	7.12e-22	GO:0016071	mRNA metabolic process
1.15	1.34e-21	GO:0008152	metabolic process
1.30	3.54e-21	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16	2.63e-20	GO:0044238	primary metabolic process
1.25	5.91e-18	GO:0034641	cellular nitrogen compound metabolic process
1.24	1.25e-17	GO:0006807	nitrogen compound metabolic process
1.79	1.65e-17	GO:0006397	mRNA processing
1.28	6.61e-17	GO:0044267	cellular protein metabolic process
1.87	1.67e-16	GO:0008380	RNA splicing
1.94	1.84e-12	GO:0000375	RNA splicing, via transesterification reactions
1.61	2.90e-12	GO:0006325	chromatin organization
1.52	5.49e-12	GO:0051276	chromosome organization
1.92	1.63e-11	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.92	1.63e-11	GO:0000398	nuclear mRNA splicing, via spliceosome
1.30	2.85e-11	GO:0006996	organelle organization
1.53	1.93e-10	GO:0044265	cellular macromolecule catabolic process
1.21	6.23e-10	GO:0071841	cellular component organization or biogenesis at cellular level
1.19	8.58e-09	GO:0019538	protein metabolic process
1.59	2.30e-08	GO:0016568	chromatin modification
1.20	2.60e-08	GO:0071842	cellular component organization at cellular level
1.21	4.96e-08	GO:0044249	cellular biosynthetic process
1.26	5.08e-08	GO:0009059	macromolecule biosynthetic process
1.25	1.10e-07	GO:0034645	cellular macromolecule biosynthetic process
1.20	1.94e-07	GO:0009058	biosynthetic process
1.55	3.01e-07	GO:0034622	cellular macromolecular complex assembly
1.59	3.19e-07	GO:0043632	modification-dependent macromolecule catabolic process
1.16	3.48e-07	GO:0071840	cellular component organization or biogenesis
1.59	3.83e-07	GO:0019941	modification-dependent protein catabolic process
1.58	3.99e-07	GO:0051603	proteolysis involved in cellular protein catabolic process
1.47	4.55e-07	GO:0034621	cellular macromolecular complex subunit organization
1.57	4.95e-07	GO:0044257	cellular protein catabolic process
1.31	9.18e-07	GO:0008104	protein localization
1.27	1.00e-06	GO:0033036	macromolecule localization
1.57	1.43e-06	GO:0006511	ubiquitin-dependent protein catabolic process
1.80	2.05e-06	GO:0010498	proteasomal protein catabolic process
1.80	2.05e-06	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.16	2.11e-06	GO:0016043	cellular component organization
1.34	3.15e-06	GO:0015031	protein transport
1.28	4.12e-06	GO:0044248	cellular catabolic process
1.39	4.74e-06	GO:0009057	macromolecule catabolic process
1.32	7.47e-06	GO:0045184	establishment of protein localization
1.92	1.23e-05	GO:0051028	mRNA transport
1.87	1.66e-05	GO:0050657	nucleic acid transport
1.87	1.66e-05	GO:0050658	RNA transport
1.87	1.66e-05	GO:0051236	establishment of RNA localization
1.68	1.90e-05	GO:0022613	ribonucleoprotein complex biogenesis
1.49	2.06e-05	GO:0030163	protein catabolic process
1.20	3.20e-05	GO:0043412	macromolecule modification
2.14	3.29e-05	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.05	3.40e-05	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.83	3.49e-05	GO:0006403	RNA localization
1.64	4.25e-05	GO:0071843	cellular component biogenesis at cellular level
1.96	5.15e-05	GO:0051438	regulation of ubiquitin-protein ligase activity
2.10	5.65e-05	GO:0051352	negative regulation of ligase activity
2.10	5.65e-05	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.28	9.96e-05	GO:0007049	cell cycle
2.07	1.06e-04	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.37	1.15e-04	GO:0000278	mitotic cell cycle
1.25	1.45e-04	GO:0044085	cellular component biogenesis
1.19	2.08e-04	GO:0006464	protein modification process
1.31	2.31e-04	GO:0046907	intracellular transport
1.99	2.57e-04	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.63	2.58e-04	GO:0034470	ncRNA processing
1.30	2.71e-04	GO:0043933	macromolecular complex subunit organization
1.95	3.26e-04	GO:0051351	positive regulation of ligase activity
1.73	3.68e-04	GO:0006333	chromatin assembly or disassembly
1.96	3.81e-04	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.61	3.84e-04	GO:0006457	protein folding
1.88	3.93e-04	GO:0051340	regulation of ligase activity
1.49	4.21e-04	GO:0006412	translation
1.75	4.33e-04	GO:0022900	electron transport chain
1.30	4.41e-04	GO:0022402	cell cycle process
1.52	4.62e-04	GO:0034660	ncRNA metabolic process
1.64	4.68e-04	GO:0016569	covalent chromatin modification
1.83	5.91e-04	GO:0034728	nucleosome organization
1.32	6.30e-04	GO:0065003	macromolecular complex assembly
1.48	6.37e-04	GO:0051325	interphase
1.70	7.79e-04	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.33	9.54e-04	GO:0051726	regulation of cell cycle
1.79	9.85e-04	GO:0031398	positive regulation of protein ubiquitination
1.40	1.18e-03	GO:0016032	viral reproduction
1.31	1.25e-03	GO:0022403	cell cycle phase
1.88	1.25e-03	GO:0031397	negative regulation of protein ubiquitination
1.68	1.33e-03	GO:0031396	regulation of protein ubiquitination
1.85	1.42e-03	GO:0006334	nucleosome assembly
1.85	1.42e-03	GO:0022904	respiratory electron transport chain
1.82	1.57e-03	GO:0031497	chromatin assembly
1.72	1.95e-03	GO:0045333	cellular respiration
1.61	2.12e-03	GO:0016570	histone modification
1.46	2.55e-03	GO:0051329	interphase of mitotic cell cycle
2.01	2.59e-03	GO:0031124	mRNA 3'-end processing
1.76	3.23e-03	GO:0065004	protein-DNA complex assembly
1.23	3.59e-03	GO:0010604	positive regulation of macromolecule metabolic process
2.20	4.14e-03	GO:0042773	ATP synthesis coupled electron transport
2.20	4.14e-03	GO:0042775	mitochondrial ATP synthesis coupled electron transport
1.68	4.87e-03	GO:0006323	DNA packaging
1.73	4.91e-03	GO:0071824	protein-DNA complex subunit organization
1.42	5.18e-03	GO:0010564	regulation of cell cycle process
1.28	6.09e-03	GO:0071844	cellular component assembly at cellular level
1.44	7.84e-03	GO:0006366	transcription from RNA polymerase II promoter
1.68	8.49e-03	GO:0042254	ribosome biogenesis
1.24	9.00e-03	GO:0032774	RNA biosynthetic process
1.21	9.30e-03	GO:0031325	positive regulation of cellular metabolic process
1.59	1.04e-02	GO:0031400	negative regulation of protein modification process
1.97	1.07e-02	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
1.97	1.07e-02	GO:0072395	signal transduction involved in cell cycle checkpoint
1.97	1.07e-02	GO:0072401	signal transduction involved in DNA integrity checkpoint
1.97	1.07e-02	GO:0072404	signal transduction involved in G1/S transition checkpoint
1.97	1.07e-02	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
1.97	1.07e-02	GO:0072422	signal transduction involved in DNA damage checkpoint
1.97	1.07e-02	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
1.97	1.07e-02	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
1.91	1.10e-02	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
1.20	1.15e-02	GO:0009893	positive regulation of metabolic process
2.42	1.36e-02	GO:0043484	regulation of RNA splicing
1.45	1.46e-02	GO:0007346	regulation of mitotic cell cycle
1.24	1.65e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.61	2.04e-02	GO:0000082	G1/S transition of mitotic cell cycle
1.24	2.10e-02	GO:0006351	transcription, DNA-dependent
1.70	2.17e-02	GO:0000077	DNA damage checkpoint
1.64	2.37e-02	GO:0007093	mitotic cell cycle checkpoint
1.20	2.55e-02	GO:0051641	cellular localization
2.04	2.61e-02	GO:0006119	oxidative phosphorylation
1.24	2.99e-02	GO:0008219	cell death
1.82	3.21e-02	GO:0031123	RNA 3'-end processing
1.21	4.01e-02	GO:0022607	cellular component assembly
1.65	4.30e-02	GO:0031570	DNA integrity checkpoint
1.23	4.75e-02	GO:0016265	death
1.24	4.82e-02	GO:0033554	cellular response to stress
1.88	4.90e-02	GO:0071158	positive regulation of cell cycle arrest

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.19	1.68e-53	GO:0043227	membrane-bounded organelle
1.19	5.80e-53	GO:0043231	intracellular membrane-bounded organelle
1.13	9.57e-52	GO:0044424	intracellular part
1.16	2.20e-51	GO:0043226	organelle
1.16	4.45e-51	GO:0043229	intracellular organelle
1.13	6.84e-51	GO:0005622	intracellular
1.25	4.61e-42	GO:0044422	organelle part
1.25	8.02e-42	GO:0044446	intracellular organelle part
1.25	1.55e-40	GO:0005634	nucleus
1.44	2.52e-37	GO:0044428	nuclear part
1.32	1.97e-36	GO:0032991	macromolecular complex
1.39	6.29e-32	GO:0070013	intracellular organelle lumen
1.39	9.89e-32	GO:0031974	membrane-enclosed lumen
1.39	1.64e-31	GO:0043233	organelle lumen
1.43	6.28e-30	GO:0031981	nuclear lumen
1.15	1.66e-28	GO:0005737	cytoplasm
1.46	1.39e-23	GO:0005654	nucleoplasm
1.26	6.40e-19	GO:0043234	protein complex
1.68	7.50e-19	GO:0030529	ribonucleoprotein complex
1.16	3.16e-18	GO:0044444	cytoplasmic part
1.50	3.71e-14	GO:0044451	nucleoplasm part
1.04	4.64e-13	GO:0044464	cell part
1.04	5.19e-13	GO:0005623	cell
2.09	2.93e-12	GO:0005681	spliceosomal complex
1.21	9.17e-11	GO:0043228	non-membrane-bounded organelle
1.21	9.17e-11	GO:0043232	intracellular non-membrane-bounded organelle
1.46	3.81e-09	GO:0005694	chromosome
1.29	7.27e-09	GO:0005739	mitochondrion
2.24	7.34e-09	GO:0071013	catalytic step 2 spliceosome
1.40	1.09e-08	GO:0031967	organelle envelope
1.38	3.71e-08	GO:0031975	envelope
1.20	1.22e-06	GO:0005829	cytosol
1.44	2.01e-06	GO:0044427	chromosomal part
1.61	2.54e-06	GO:0000785	chromatin
1.19	5.47e-06	GO:0031090	organelle membrane
1.38	3.23e-05	GO:0005730	nucleolus
1.33	3.47e-05	GO:0044429	mitochondrial part
1.46	6.36e-05	GO:0019866	organelle inner membrane
1.55	1.04e-04	GO:0016604	nuclear body
2.07	1.09e-04	GO:0000502	proteasome complex
1.52	2.14e-04	GO:0005635	nuclear envelope
2.31	3.50e-04	GO:0005747	mitochondrial respiratory chain complex I
2.31	3.50e-04	GO:0030964	NADH dehydrogenase complex
2.31	3.50e-04	GO:0045271	respiratory chain complex I
1.44	4.52e-04	GO:0005743	mitochondrial inner membrane
2.02	4.74e-04	GO:0005746	mitochondrial respiratory chain
1.97	6.16e-04	GO:0070469	respiratory chain
1.93	8.92e-04	GO:0005643	nuclear pore
1.70	9.40e-04	GO:0044455	mitochondrial membrane part
2.00	9.71e-04	GO:0000123	histone acetyltransferase complex
1.67	2.30e-03	GO:0016607	nuclear speck
1.34	3.11e-03	GO:0031966	mitochondrial membrane
1.52	4.08e-03	GO:0005840	ribosome
1.33	4.09e-03	GO:0005740	mitochondrial envelope
1.89	1.10e-02	GO:0000786	nucleosome
1.82	1.62e-02	GO:0034399	nuclear periphery
1.73	1.84e-02	GO:0046930	pore complex
1.54	2.69e-02	GO:0031965	nuclear membrane
1.15	4.48e-02	GO:0012505	endomembrane system

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	1.14e-27	GO:0005515	protein binding
1.59	1.21e-23	GO:0003723	RNA binding
1.08	1.21e-20	GO:0005488	binding
1.22	3.90e-10	GO:0000166	nucleotide binding
1.16	3.50e-08	GO:0003676	nucleic acid binding
1.17	5.94e-04	GO:0035639	purine ribonucleoside triphosphate binding
2.34	6.46e-04	GO:0003954	NADH dehydrogenase activity
2.34	6.46e-04	GO:0008137	NADH dehydrogenase (ubiquinone) activity
2.34	6.46e-04	GO:0050136	NADH dehydrogenase (quinone) activity
1.17	6.89e-04	GO:0017076	purine nucleotide binding
1.17	1.11e-03	GO:0032553	ribonucleotide binding
1.17	1.11e-03	GO:0032555	purine ribonucleotide binding
1.19	1.26e-03	GO:0030554	adenyl nucleotide binding
1.18	1.82e-03	GO:0005524	ATP binding
1.18	1.89e-03	GO:0032559	adenyl ribonucleotide binding
1.61	3.33e-03	GO:0003714	transcription corepressor activity
1.37	4.16e-03	GO:0000988	protein binding transcription factor activity
1.37	4.16e-03	GO:0000989	transcription factor binding transcription factor activity
1.37	5.81e-03	GO:0003712	transcription cofactor activity
2.09	1.11e-02	GO:0016655	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
1.64	4.32e-02	GO:0008026	ATP-dependent helicase activity
1.64	4.32e-02	GO:0070035	purine NTP-dependent helicase activity