Motif ID: ZIC1..3.p2

Z-value: 1.202


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZIC3chrX_+_1366483130.479.2e-03Click!
ZIC1chr3_+_1471271510.202.9e-01Click!
ZIC2chr13_+_100633977,
chr13_+_100634257
-0.009.9e-01Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_26205327 3.433 KIF3C
kinesin family member 3C
chrX_-_15872921 2.318 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr19_-_51456159 2.220 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chrX_-_15872905 2.142


chr16_+_3405888 2.066 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr19_-_41859519 1.855 TGFB1
transforming growth factor, beta 1
chr2_-_26205437 1.817 NM_002254
KIF3C
kinesin family member 3C
chr15_+_39873276 1.565 NM_003246
THBS1
thrombospondin 1
chrX_-_15872882 1.492 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr17_+_39968961 1.387 NM_021939
FKBP10
FK506 binding protein 10, 65 kDa
chr2_+_70142303 1.332 MXD1
MAX dimerization protein 1
chr1_+_150521786 1.253 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr22_-_37823503 1.246 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr19_-_44285012 1.224 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_-_90712510 1.185 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_-_205391180 1.166 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr5_-_157002739 1.157 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr1_+_38158176 1.133 CDCA8
cell division cycle associated 8
chr1_+_38158129 1.126 NM_018101
CDCA8
cell division cycle associated 8
chr21_-_28217692 1.125 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr8_+_37887990 1.125 NM_004095
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr19_+_676346 1.113 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr21_-_28217272 1.069 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr6_-_109777171 1.043 NM_001159291
NM_022765
MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr19_-_44285407 1.040 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_52751114 1.021 PRKG1
protein kinase, cGMP-dependent, type I
chr19_-_41859332 1.018 TGFB1
transforming growth factor, beta 1
chrX_-_15872938 1.005 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_70142236 0.999 MXD1
MAX dimerization protein 1
chr22_+_19467467 0.996 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr11_-_123525300 0.987 NM_001040151
NM_018400
SCN3B

sodium channel, voltage-gated, type III, beta

chr19_+_4910339 0.961 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr20_+_62328002 0.941 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr19_-_41859253 0.933 TGFB1
transforming growth factor, beta 1
chr19_-_41858948 0.923 TGFB1
transforming growth factor, beta 1
chr17_-_74533623 0.920 NM_134268
CYGB
cytoglobin
chr5_-_44388666 0.903 NM_004465
FGF10
fibroblast growth factor 10
chr16_+_30194730 0.889 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr6_-_109776946 0.881 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr19_+_2096930 0.872 IZUMO4
IZUMO family member 4
chr3_-_73673978 0.868 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr1_-_236030170 0.867


chr22_+_45098091 0.864 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr9_+_131183225 0.859 CERCAM
cerebral endothelial cell adhesion molecule
chr11_-_123524881 0.858 SCN3B
sodium channel, voltage-gated, type III, beta
chr22_+_19467413 0.857 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr1_-_200589856 0.844 NM_014875
KIF14
kinesin family member 14
chr16_+_31483066 0.822 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr9_-_35958095 0.812 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr15_-_75017710 0.803 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr4_-_174450529 0.796 HAND2
heart and neural crest derivatives expressed 2
chr14_+_64971417 0.794 ZBTB1
zinc finger and BTB domain containing 1
chrX_-_15873094 0.788 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_9983570 0.779 NM_005680
TAF1B
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
chr7_-_27135524 0.778 NM_005522
NM_153620
HOXA1

homeobox A1

chr9_+_131183122 0.767 CERCAM
cerebral endothelial cell adhesion molecule
chr10_-_86001197 0.757 NM_015613
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr6_-_53213699 0.734 ELOVL5
ELOVL fatty acid elongase 5
chr19_-_14629227 0.725 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr12_+_54943176 0.719 NM_000924
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr10_-_43762366 0.719 NM_145313
RASGEF1A
RasGEF domain family, member 1A
chr6_-_109777085 0.718 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr12_+_54943358 0.706 PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr16_+_725679 0.701 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr1_+_183155361 0.699 LAMC2
laminin, gamma 2
chr14_+_21525980 0.696 NM_138331
RNASE8
ribonuclease, RNase A family, 8
chr8_+_31497267 0.689 NM_013962
NRG1
neuregulin 1
chr8_+_19796840 0.688 LPL
lipoprotein lipase
chr12_+_79258794 0.685 SYT1
synaptotagmin I
chr1_+_183155173 0.683 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr20_+_43030005 0.678 HNF4A
hepatocyte nuclear factor 4, alpha
chr11_-_123065836 0.676 CLMP
CXADR-like membrane protein
chr12_-_95942570 0.674 NM_001042403
USP44
ubiquitin specific peptidase 44
chr22_+_22569155 0.671


chr12_-_6798419 0.667 ZNF384
zinc finger protein 384
chr20_-_52790511 0.666 NM_000782
NM_001128915
CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

chr22_-_30685485 0.663 NM_001037666
GATSL3
GATS protein-like 3
chr9_+_112810877 0.660 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr12_+_49716970 0.659 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr2_-_28113954 0.655 LOC100302650
uncharacterized LOC100302650
chr11_+_65554504 0.653 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr1_+_43824598 0.652 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr13_-_30881556 0.652 NM_032116
KATNAL1
katanin p60 subunit A-like 1
chr11_+_15133969 0.648 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr13_-_30881141 0.648 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr11_+_131780537 0.642 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr6_-_109776942 0.640 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr22_+_31489343 0.639 SMTN
smoothelin
chr17_-_39280377 0.638 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr20_+_44441334 0.631 UBE2C
ubiquitin-conjugating enzyme E2C
chr8_+_103563847 0.630 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr17_-_44895962 0.627 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr21_+_34100388 0.627 GCFC1-AS1
GCFC1 antisense RNA 1 (non-protein coding)
chr21_+_34442550 0.621 OLIG1
oligodendrocyte transcription factor 1
chr5_-_39270708 0.620 NM_001243093
FYB
FYN binding protein
chr6_+_34205029 0.612 HMGA1
high mobility group AT-hook 1
chrX_+_151903218 0.611 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chr12_+_96588000 0.610 NM_005230
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr3_+_63263814 0.603 NM_001130003
SYNPR
synaptoporin
chr20_-_23030141 0.603 NM_000361
THBD
thrombomodulin
chr1_+_38158189 0.602 CDCA8
cell division cycle associated 8
chr7_+_130131921 0.602 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr12_+_56522043 0.598 ESYT1
extended synaptotagmin-like protein 1
chr14_-_105444693 0.598 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr12_+_56521953 0.595 NM_001184796
NM_015292
ESYT1

extended synaptotagmin-like protein 1

chrX_-_15872871 0.594 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_+_156863522 0.593 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr3_+_49591897 0.593 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr12_+_96588254 0.588 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr6_+_151561508 0.587 AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_64527369 0.585 PYGM
phosphorylase, glycogen, muscle
chr4_-_159092509 0.585 FAM198B
family with sequence similarity 198, member B
chr21_+_34442446 0.579 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr7_+_27135672 0.577 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr21_-_47648618 0.576 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr5_+_157158322 0.575 NM_017872
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr10_+_8097350 0.570 GATA3
GATA binding protein 3
chr9_-_113800243 0.569 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr7_+_139478033 0.569 NM_001130966
NM_001166254
TBXAS1

thromboxane A synthase 1 (platelet)

chr17_-_50237160 0.569 NM_001082533
CA10
carbonic anhydrase X
chr16_+_30194925 0.568 CORO1A
coronin, actin binding protein, 1A
chr12_-_6798528 0.567 NM_133476
ZNF384
zinc finger protein 384
chr7_-_37488408 0.566 ELMO1
engulfment and cell motility 1
chr12_+_56522049 0.565 ESYT1
extended synaptotagmin-like protein 1
chr20_+_62328068 0.563 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr10_+_75673346 0.562 PLAU
plasminogen activator, urokinase
chr19_+_2096792 0.560 NM_001031735
NM_001039846
IZUMO4

IZUMO family member 4

chr1_+_182992694 0.560


chr2_+_70142152 0.556 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr10_-_69455926 0.556 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr19_-_50143350 0.551 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr17_+_39261640 0.550 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr17_-_50237342 0.548 NM_001082534
CA10
carbonic anhydrase X
chr20_+_44441247 0.548 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr11_-_70963619 0.547 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr2_+_16082148 0.545 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr12_+_56522202 0.544 ESYT1
extended synaptotagmin-like protein 1
chr7_-_56119115 0.541 NM_004577
PSPH
phosphoserine phosphatase
chr17_-_8059637 0.528 PER1
period homolog 1 (Drosophila)
chr19_+_47105327 0.526 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr11_-_61658853 0.526 NM_021727
FADS3
fatty acid desaturase 3
chr3_+_10068139 0.524 FANCD2
Fanconi anemia, complementation group D2
chr12_+_26348488 0.520 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr7_+_77166750 0.520 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr13_-_74707913 0.519 NM_007249
KLF12
Kruppel-like factor 12
chr6_-_109776832 0.517 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr6_+_151561653 0.513 AKAP12
A kinase (PRKA) anchor protein 12
chr5_+_52776408 0.512 FST
follistatin
chr8_+_38965049 0.511 NM_145004
ADAM32
ADAM metallopeptidase domain 32
chr1_+_65991357 0.510 NM_001198687
NM_001198688
NM_001198689
LEPR


leptin receptor


chr3_+_50306578 0.509 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr16_+_88705000 0.505 NM_013278
IL17C
interleukin 17C
chr16_+_67282774 0.495 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr17_+_1959512 0.495 NM_001098202
HIC1
hypermethylated in cancer 1
chr17_-_3461288 0.493 NM_145068
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr7_-_37488554 0.490 NM_014800
ELMO1
engulfment and cell motility 1
chr19_-_14629235 0.490


chr1_+_183155393 0.489 LAMC2
laminin, gamma 2
chr7_+_103969103 0.489 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr12_-_58160823 0.487 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr20_-_35201677 0.486


chr11_+_65554566 0.485 OVOL1
ovo-like 1(Drosophila)
chr10_-_116164514 0.483 NM_001001936
NM_032550
AFAP1L2

actin filament associated protein 1-like 2

chr10_-_25012168 0.480 ARHGAP21
Rho GTPase activating protein 21
chr8_+_22225173 0.479 SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr17_-_43209681 0.478 NM_133373
PLCD3
phospholipase C, delta 3
chr17_+_40834571 0.478 NM_003632
CNTNAP1
contactin associated protein 1
chr17_-_37307694 0.474 PLXDC1
plexin domain containing 1
chr6_+_34205369 0.473 HMGA1
high mobility group AT-hook 1
chr20_+_25228698 0.473 NM_002862
PYGB
phosphorylase, glycogen; brain
chr4_+_24797203 0.471 SOD3
superoxide dismutase 3, extracellular
chr19_+_45417576 0.468 APOC1
apolipoprotein C-I
chr5_+_161275541 0.466 NM_001127645
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr16_+_67686813 0.464 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr5_+_52776263 0.457 NM_006350
NM_013409
FST

follistatin

chr12_+_54366909 0.456 NM_014212
HOXC11
homeobox C11
chr11_+_111783459 0.455 NM_001541
HSPB2-C11orf52
HSPB2
HSPB2-C11orf52 readthrough (non-protein coding)
heat shock 27kDa protein 2
chr2_+_16081945 0.454 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr11_-_19262424 0.454 NM_024680
E2F8
E2F transcription factor 8
chr6_-_33756905 0.454 NM_181336
LEMD2
LEM domain containing 2
chr20_+_44441671 0.453 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr7_+_27225009 0.452 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr19_+_33622997 0.452 NM_173479
WDR88
WD repeat domain 88
chr6_-_33756885 0.450 LEMD2
LEM domain containing 2
chr18_-_6414900 0.449 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr17_-_39274587 0.446 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr11_+_369723 0.446 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr2_-_99347430 0.446 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_152881022 0.444 NM_005547
IVL
involucrin
chr4_+_24797084 0.440 NM_003102
SOD3
superoxide dismutase 3, extracellular
chr17_-_33416238 0.439 RFFL
ring finger and FYVE-like domain containing 1
chr3_+_47021146 0.439 NM_015175
NBEAL2
neurobeachin-like 2
chr6_+_26204779 0.438 NM_003545
HIST1H4E
histone cluster 1, H4e
chr2_-_219925237 0.438 NM_002181
IHH
Indian hedgehog
chr11_-_12030539 0.438 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr14_+_85996512 0.435 FLRT2
fibronectin leucine rich transmembrane protein 2
chr5_+_86563594 0.434 RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr19_-_46999149 0.434 NM_020709
PNMAL2
PNMA-like 2
chr12_-_6798619 0.433 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr20_+_43029973 0.432 HNF4A
hepatocyte nuclear factor 4, alpha

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 8.47e-16 GO:0032502 developmental process
1.38 1.87e-15 GO:0023052 signaling
1.43 4.61e-14 GO:0048731 system development
1.40 6.69e-14 GO:0048856 anatomical structure development
1.38 9.17e-14 GO:0007275 multicellular organismal development
1.22 2.88e-13 GO:0050794 regulation of cellular process
1.51 3.56e-13 GO:0030154 cell differentiation
1.20 6.74e-13 GO:0065007 biological regulation
1.49 1.59e-12 GO:0048869 cellular developmental process
1.59 3.97e-12 GO:0007399 nervous system development
1.20 9.62e-12 GO:0050789 regulation of biological process
1.12 2.32e-11 GO:0009987 cellular process
1.77 5.78e-11 GO:0048699 generation of neurons
1.73 2.14e-10 GO:0022008 neurogenesis
1.54 4.72e-10 GO:0009653 anatomical structure morphogenesis
1.33 5.54e-10 GO:0007165 signal transduction
1.47 4.91e-08 GO:0023051 regulation of signaling
1.75 6.11e-08 GO:0030182 neuron differentiation
1.22 9.00e-08 GO:0032501 multicellular organismal process
1.30 9.09e-08 GO:0016043 cellular component organization
1.80 4.26e-07 GO:0048666 neuron development
1.48 7.58e-07 GO:0009966 regulation of signal transduction
1.28 1.12e-06 GO:0071840 cellular component organization or biogenesis
1.60 1.15e-06 GO:0048468 cell development
1.24 1.51e-06 GO:0051716 cellular response to stimulus
1.88 2.67e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.39 3.52e-06 GO:0048583 regulation of response to stimulus
2.00 4.74e-06 GO:0007411 axon guidance
1.86 9.28e-06 GO:0007409 axonogenesis
1.78 1.50e-05 GO:0000904 cell morphogenesis involved in differentiation
1.37 1.56e-05 GO:0048513 organ development
1.78 1.68e-05 GO:0019226 transmission of nerve impulse
1.78 1.68e-05 GO:0035637 multicellular organismal signaling
1.81 3.21e-05 GO:0048812 neuron projection morphogenesis
1.76 3.47e-05 GO:0031175 neuron projection development
2.13 4.42e-05 GO:0051129 negative regulation of cellular component organization
1.28 1.15e-04 GO:0048518 positive regulation of biological process
1.29 1.20e-04 GO:0071842 cellular component organization at cellular level
1.97 2.10e-04 GO:0051960 regulation of nervous system development
1.47 2.29e-04 GO:0010646 regulation of cell communication
1.48 2.49e-04 GO:0007154 cell communication
1.56 3.17e-04 GO:0007267 cell-cell signaling
4.43 4.13e-04 GO:0009954 proximal/distal pattern formation
1.87 5.59e-04 GO:0060284 regulation of cell development
1.26 6.52e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 6.95e-04 GO:0031323 regulation of cellular metabolic process
1.52 7.42e-04 GO:0051128 regulation of cellular component organization
1.54 8.41e-04 GO:2000026 regulation of multicellular organismal development
1.61 8.80e-04 GO:0000902 cell morphogenesis
2.27 9.37e-04 GO:0031344 regulation of cell projection organization
1.98 9.83e-04 GO:0050767 regulation of neurogenesis
1.66 1.03e-03 GO:0032990 cell part morphogenesis
1.28 1.13e-03 GO:0048522 positive regulation of cellular process
1.66 1.29e-03 GO:0048858 cell projection morphogenesis
1.58 1.48e-03 GO:0030030 cell projection organization
1.85 1.73e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.06 1.88e-03 GO:0045664 regulation of neuron differentiation
2.35 1.91e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.64 2.12e-03 GO:0006935 chemotaxis
1.64 2.12e-03 GO:0042330 taxis
2.33 2.37e-03 GO:0022604 regulation of cell morphogenesis
1.48 2.44e-03 GO:0009891 positive regulation of biosynthetic process
1.46 3.78e-03 GO:0050793 regulation of developmental process
1.68 3.89e-03 GO:0007268 synaptic transmission
1.56 4.00e-03 GO:0032989 cellular component morphogenesis
1.48 4.06e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.19 4.09e-03 GO:0019222 regulation of metabolic process
1.51 4.36e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.73 5.18e-03 GO:0048598 embryonic morphogenesis
1.56 6.71e-03 GO:0009887 organ morphogenesis
1.35 7.75e-03 GO:0035556 intracellular signal transduction
2.26 1.08e-02 GO:0010975 regulation of neuron projection development
1.51 1.18e-02 GO:0045595 regulation of cell differentiation
1.23 1.33e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 1.51e-02 GO:0032879 regulation of localization
1.20 1.57e-02 GO:0080090 regulation of primary metabolic process
1.26 1.58e-02 GO:0048523 negative regulation of cellular process
2.04 1.83e-02 GO:0071902 positive regulation of protein serine/threonine kinase activity
1.47 1.84e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 1.87e-02 GO:0009888 tissue development
1.51 1.99e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.46 2.01e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.57 2.33e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.34 2.54e-02 GO:0051239 regulation of multicellular organismal process
1.43 2.76e-02 GO:0040011 locomotion
2.09 2.89e-02 GO:0034330 cell junction organization
1.48 3.04e-02 GO:0009790 embryo development
2.11 3.08e-02 GO:0043406 positive regulation of MAP kinase activity
1.65 3.30e-02 GO:0007264 small GTPase mediated signal transduction
1.19 3.63e-02 GO:0060255 regulation of macromolecule metabolic process
1.24 3.73e-02 GO:0048519 negative regulation of biological process
1.60 3.82e-02 GO:0023057 negative regulation of signaling
1.79 3.99e-02 GO:0045596 negative regulation of cell differentiation
1.48 4.01e-02 GO:0010628 positive regulation of gene expression
1.60 4.20e-02 GO:0010648 negative regulation of cell communication
1.35 4.65e-02 GO:0031325 positive regulation of cellular metabolic process
1.59 4.93e-02 GO:0061024 membrane organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.36 1.81e-07 GO:0044459 plasma membrane part
1.72 5.56e-07 GO:0030054 cell junction
1.41 2.07e-06 GO:0005856 cytoskeleton
1.08 6.01e-05 GO:0005622 intracellular
2.25 1.36e-04 GO:0005912 adherens junction
2.13 3.89e-04 GO:0070161 anchoring junction
2.50 4.14e-04 GO:0005925 focal adhesion
1.11 4.62e-04 GO:0005737 cytoplasm
1.08 5.22e-04 GO:0044424 intracellular part
2.36 1.08e-03 GO:0030055 cell-substrate junction
2.38 1.34e-03 GO:0005924 cell-substrate adherens junction
2.18 1.43e-03 GO:0034703 cation channel complex
1.21 4.50e-03 GO:0043234 protein complex
1.60 8.16e-03 GO:0045202 synapse
1.84 9.80e-03 GO:0034702 ion channel complex
5.31 1.00e-02 GO:0001518 voltage-gated sodium channel complex
1.70 1.09e-02 GO:0015629 actin cytoskeleton
1.67 1.17e-02 GO:0044433 cytoplasmic vesicle part
1.90 1.38e-02 GO:0030424 axon
1.58 1.66e-02 GO:0043005 neuron projection
1.70 1.95e-02 GO:0012506 vesicle membrane
1.15 1.96e-02 GO:0071944 cell periphery
1.23 2.27e-02 GO:0005829 cytosol
1.37 2.56e-02 GO:0042995 cell projection
1.70 2.76e-02 GO:0030659 cytoplasmic vesicle membrane
1.15 3.49e-02 GO:0005886 plasma membrane
1.33 3.96e-02 GO:0044430 cytoskeletal part
1.88 4.19e-02 GO:0030136 clathrin-coated vesicle
1.78 4.85e-02 GO:0030135 coated vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 4.85e-13 GO:0005515 protein binding
1.08 3.13e-06 GO:0005488 binding
1.52 4.19e-06 GO:0001071 nucleic acid binding transcription factor activity
1.52 4.19e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 2.71e-04 GO:0043565 sequence-specific DNA binding
1.87 5.47e-04 GO:0005261 cation channel activity
2.13 3.17e-03 GO:0022843 voltage-gated cation channel activity
2.59 3.67e-03 GO:0005262 calcium channel activity
1.38 6.83e-03 GO:0030528 transcription regulator activity
5.12 7.21e-03 GO:0005248 voltage-gated sodium channel activity
1.42 2.14e-02 GO:0042802 identical protein binding
1.66 2.61e-02 GO:0016563 transcription activator activity