Motif ID: ZNF423.p2

Z-value: 1.516


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_498609170.261.7e-01Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151561653 4.679 AKAP12
A kinase (PRKA) anchor protein 12
chr19_-_11689765 4.482 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr5_+_150399980 4.467 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr2_-_224903933 4.267 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr5_+_150400132 4.248 GPX3
glutathione peroxidase 3 (plasma)
chr5_-_136834887 4.086 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr12_-_125348266 3.934 SCARB1
scavenger receptor class B, member 1
chr11_+_60691911 3.740 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr1_+_20915440 3.728 NM_001785
CDA
cytidine deaminase
chr19_-_11689591 3.665 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr11_-_107729523 3.621 SLC35F2
solute carrier family 35, member F2
chr6_-_30654978 3.570 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr11_+_61595633 3.432 NM_004265
FADS2
fatty acid desaturase 2
chr11_-_107729492 3.338 SLC35F2
solute carrier family 35, member F2
chr11_-_61062697 3.253 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr17_+_39969205 3.253 FKBP10
FK506 binding protein 10, 65 kDa
chr12_-_125348422 3.237 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr1_-_204121144 3.231 NM_018208
ETNK2
ethanolamine kinase 2
chr12_-_125348346 3.226 SCARB1
scavenger receptor class B, member 1
chr17_+_39969200 3.222 FKBP10
FK506 binding protein 10, 65 kDa
chr7_+_48128225 3.210 NM_181597
UPP1
uridine phosphorylase 1
chr8_+_22022644 3.206 NM_001199
NM_006129
BMP1

bone morphogenetic protein 1

chr8_+_22022677 3.199 BMP1
bone morphogenetic protein 1
chr6_+_151561094 3.085 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_11200124 3.063 LDLR
low density lipoprotein receptor
chr13_+_110959592 3.025 NM_001846
COL4A2
collagen, type IV, alpha 2
chr1_-_204120909 3.009 ETNK2
ethanolamine kinase 2
chr7_-_50860665 2.977 GRB10
growth factor receptor-bound protein 10
chr8_+_22022872 2.969 BMP1
bone morphogenetic protein 1
chr4_+_75310852 2.959 NM_001657
AREG
amphiregulin
chr18_+_33877630 2.941 NM_025135
FHOD3
formin homology 2 domain containing 3
chr4_+_4388804 2.916 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr9_-_131486371 2.902 NM_032799
ZDHHC12
zinc finger, DHHC-type containing 12
chr3_-_52567708 2.888 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr3_-_52567809 2.822 NT5DC2
5'-nucleotidase domain containing 2
chr11_+_844111 2.601 TSPAN4
tetraspanin 4
chr22_-_37823503 2.601 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr10_-_108924287 2.593 NM_001013031
NM_001206569
NM_001206570
NM_001206571
NM_001206572
NM_052918
SORCS1





sortilin-related VPS10 domain containing receptor 1





chr1_-_200589856 2.562 NM_014875
KIF14
kinesin family member 14
chr19_+_11200146 2.538 LDLR
low density lipoprotein receptor
chr10_+_17271341 2.508 VIM
vimentin
chrX_+_152954965 2.507 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_-_97601654 2.461


chr16_-_56459371 2.446 NM_001144
AMFR
autocrine motility factor receptor
chr19_-_2041862 2.421 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr10_-_121296044 2.415 NM_002925
RGS10
regulator of G-protein signaling 10
chr10_+_17271276 2.406 VIM
vimentin
chr15_+_41523465 2.362 CHP
calcium binding protein P22
chr5_-_134369841 2.355 NM_002653
PITX1
paired-like homeodomain 1
chr10_+_17271302 2.348 VIM
vimentin
chr17_+_74380676 2.345 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr9_+_112542496 2.324 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr4_+_4388717 2.299 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr1_-_22263676 2.276 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr11_+_69455978 2.273 CCND1
cyclin D1
chr10_+_17271277 2.269 VIM
vimentin
chr6_+_151186884 2.264 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr18_-_21242592 2.251 NM_173505
ANKRD29
ankyrin repeat domain 29
chr4_+_75480628 2.236 NM_001657
AREG
amphiregulin
chr1_+_32050510 2.228 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr19_+_11200037 2.213 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr16_+_55543044 2.208 LPCAT2
lysophosphatidylcholine acyltransferase 2
chr4_+_8582216 2.166 NM_080819
GPR78
G protein-coupled receptor 78
chr6_+_151187064 2.165 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr19_+_38810751 2.148 KCNK6
potassium channel, subfamily K, member 6
chr19_-_41858948 2.125 TGFB1
transforming growth factor, beta 1
chr3_-_195808980 2.091 TFRC
transferrin receptor (p90, CD71)
chr17_+_6347733 2.076 NM_001195228
NM_019013
FAM64A

family with sequence similarity 64, member A

chr11_+_61595772 2.064 FADS2
fatty acid desaturase 2
chr19_+_45147207 2.061 PVR
poliovirus receptor
chr17_-_76921205 2.055 TIMP2
TIMP metallopeptidase inhibitor 2
chr21_+_30452872 2.052 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr6_+_151561508 2.049 AKAP12
A kinase (PRKA) anchor protein 12
chr3_+_6902797 2.030 NM_000844
NM_181874
GRM7

glutamate receptor, metabotropic 7

chr19_+_4910339 2.017 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr19_+_38810461 2.007 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chrX_-_107019001 2.006 NM_198057
TSC22D3
TSC22 domain family, member 3
chr16_+_71392615 1.991 NM_001740
NM_007088
CALB2

calbindin 2

chr6_+_151186814 1.945 NM_001242767
NM_001242769
NM_015440
MTHFD1L


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr19_+_38810540 1.942 KCNK6
potassium channel, subfamily K, member 6
chr3_-_16555128 1.938 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr1_+_27320132 1.931 NM_001013642
TRNP1
TMF1-regulated nuclear protein 1
chr5_-_137667453 1.927 NM_001790
NM_022809
CDC25C

cell division cycle 25 homolog C (S. pombe)

chr17_+_76210276 1.924 NM_001012270
NM_001012271
NM_001168
BIRC5


baculoviral IAP repeat containing 5


chrX_-_51239426 1.907 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr6_-_131384321 1.906 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chrX_-_51239295 1.877 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr3_-_48594209 1.865 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr19_+_8429010 1.847 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chr19_-_2042022 1.840 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr17_-_76921453 1.840 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr16_+_58498216 1.828 NDRG4
NDRG family member 4
chrX_-_109561427 1.802 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_-_23053732 1.797 NM_032581
FAM126A
family with sequence similarity 126, member A
chr2_-_220094354 1.797 NM_001077198
NM_024085
ATG9A

ATG9 autophagy related 9 homolog A (S. cerevisiae)

chr10_-_135090325 1.783 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr1_+_109419748 1.773 GPSM2
G-protein signaling modulator 2
chr16_+_28986024 1.760 NM_001142448
NM_001142449
NM_001142450
NM_001142451
NM_032038
SPIN1
SPNS1




spindlin 1
spinster homolog 1 (Drosophila)




chr21_-_46962281 1.734 NM_001205206
NM_194255
SLC19A1

solute carrier family 19 (folate transporter), member 1

chrX_+_49028183 1.729 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr1_+_109419601 1.720 NM_013296
GPSM2
G-protein signaling modulator 2
chr8_-_125486808 1.704


chr8_-_121823696 1.691 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr3_-_16554992 1.677 RFTN1
raftlin, lipid raft linker 1
chr1_+_55505148 1.672 NM_174936
PCSK9
proprotein convertase subtilisin/kexin type 9
chr17_+_74381419 1.661 SPHK1
sphingosine kinase 1
chr19_-_15311773 1.660 NM_000435
NOTCH3
notch 3
chr1_-_155177685 1.644 NM_001252607
NM_001252608
NM_007112
THBS3


thrombospondin 3


chr3_+_171758289 1.628 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr17_+_76210329 1.623 BIRC5
baculoviral IAP repeat containing 5
chr1_-_6580068 1.617 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_+_48128738 1.613 NM_003364
UPP1
uridine phosphorylase 1
chr11_+_844062 1.606 NM_001025234
TSPAN4
tetraspanin 4
chr17_-_76183074 1.604 NM_003258
TK1
thymidine kinase 1, soluble
chr7_+_100797685 1.587 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr11_-_61062534 1.585 VWCE
von Willebrand factor C and EGF domains
chr1_+_100731797 1.578 RTCD1
RNA terminal phosphate cyclase domain 1
chr1_-_193028389 1.571 UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr7_-_23053674 1.548 FAM126A
family with sequence similarity 126, member A
chr4_+_4387982 1.546 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr21_-_44496423 1.544 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr10_-_76995685 1.523 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr6_+_11094265 1.513 NM_001135575
C6orf228
chromosome 6 open reading frame 228
chr1_+_55505207 1.510 PCSK9
proprotein convertase subtilisin/kexin type 9
chrX_+_64887534 1.495 MSN
moesin
chr10_+_3109708 1.487 NM_002627
PFKP
phosphofructokinase, platelet
chr1_+_155278677 1.472 NM_001135821
FDPS
farnesyl diphosphate synthase
chr20_+_361272 1.464 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr19_-_51472003 1.460 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr1_-_6546013 1.441 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_+_45147090 1.440 NM_001135768
NM_001135769
NM_001135770
NM_006505
PVR



poliovirus receptor



chr16_+_27325244 1.435 NM_000418
NM_001008699
IL4R

interleukin 4 receptor

chr17_+_36584692 1.429 NM_001199417
ARHGAP23
Rho GTPase activating protein 23
chr19_+_42817434 1.427 NM_173633
TMEM145
transmembrane protein 145
chrX_-_109561314 1.417 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr14_-_103995336 1.413


chr1_+_155278727 1.411 FDPS
farnesyl diphosphate synthase
chr19_+_56154973 1.410 NM_016535
ZNF581
zinc finger protein 581
chr19_+_45147180 1.408 PVR
poliovirus receptor
chr16_+_71392637 1.401 CALB2
calbindin 2
chr9_+_116638544 1.397 NM_133374
ZNF618
zinc finger protein 618
chr2_-_219157207 1.366 NM_022152
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr11_-_18127584 1.364 NM_138421
SAAL1
serum amyloid A-like 1
chr3_-_50374875 1.363 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr9_-_37904098 1.362 MCART1
mitochondrial carrier triple repeat 1
chr3_-_195808934 1.355 TFRC
transferrin receptor (p90, CD71)
chr3_-_195808958 1.351 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr22_+_38599026 1.347 NM_001161573
MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr10_+_102106771 1.346 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr11_-_66725790 1.336 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr5_-_134369571 1.336 PITX1
paired-like homeodomain 1
chr3_-_50374795 1.335 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr3_-_50374749 1.332 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr2_-_74669005 1.332 RTKN
rhotekin
chr19_+_36024313 1.324 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr5_+_169010637 1.322 NM_017785
CCDC99
coiled-coil domain containing 99
chr11_-_441995 1.316 NM_001012302
ANO9
anoctamin 9
chr19_-_10420220 1.306 NM_001103167
ZGLP1
zinc finger, GATA-like protein 1
chr19_-_11266451 1.299 NM_182513
SPC24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr11_-_47207938 1.295 NM_001184974
NM_016223
PACSIN3

protein kinase C and casein kinase substrate in neurons 3

chr11_-_61584228 1.286 FADS1
fatty acid desaturase 1
chr19_-_10679620 1.284 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chr7_-_73133917 1.280 NM_001165903
NM_004603
STX1A

syntaxin 1A (brain)

chr19_+_45582469 1.279 NM_001007270
NM_001007269
NM_024707
GEMIN7


gem (nuclear organelle) associated protein 7


chr3_-_98620452 1.272 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr2_+_14772839 1.262 FAM84A
family with sequence similarity 84, member A
chr17_-_74581934 1.260 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr11_-_61658853 1.253 NM_021727
FADS3
fatty acid desaturase 3
chr17_+_80190107 1.243 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chrX_+_118533324 1.241 SLC25A43
solute carrier family 25, member 43
chr3_+_156392714 1.239 NM_001184717
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr12_-_120554551 1.238 RAB35
RAB35, member RAS oncogene family
chr19_+_45174723 1.237 NM_001127893
NM_020219
CEACAM19

carcinoembryonic antigen-related cell adhesion molecule 19

chr1_+_55271735 1.234 NM_001110533
NM_152607
C1orf177

chromosome 1 open reading frame 177

chrX_+_56258785 1.232 NM_007250
NM_001159296
KLF8

Kruppel-like factor 8

chr14_-_71275732 1.217 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr19_+_45971249 1.215 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr6_-_43596764 1.213 GTPBP2
GTP binding protein 2
chr2_-_47142939 1.211 MCFD2
multiple coagulation factor deficiency 2
chr11_+_76745434 1.204 NM_138706
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr1_-_17307107 1.200 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr19_-_4103200 1.191 MAP2K2
mitogen-activated protein kinase kinase 2
chr19_+_54385429 1.187 NM_002739
PRKCG
protein kinase C, gamma
chr9_-_37904331 1.185 NM_033412
MCART1
mitochondrial carrier triple repeat 1
chr2_+_62932786 1.180 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr3_-_195808997 1.178 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr12_-_120554453 1.178 RAB35
RAB35, member RAS oncogene family
chr11_-_61584451 1.174 NM_013402
FADS1
fatty acid desaturase 1
chr8_+_41386765 1.170 GINS4
GINS complex subunit 4 (Sld5 homolog)
chrX_+_64887510 1.169 NM_002444
MSN
moesin
chr2_-_47142950 1.150 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr17_-_37764165 1.149 NM_006160
NEUROD2
neurogenic differentiation 2
chr19_+_18391252 1.140


chr1_+_100731696 1.135 NM_001130841
NM_003729
RTCD1

RNA terminal phosphate cyclase domain 1

chr19_-_4123871 1.134 MAP2K2
mitogen-activated protein kinase kinase 2
chr9_+_125133322 1.134 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chrX_-_152939764 1.130 NM_001039582
PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr7_+_76139744 1.130 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr7_-_27192201 1.128


chr1_+_150480584 1.127 ECM1
extracellular matrix protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 1.24e-05 GO:0023052 signaling
1.30 4.28e-04 GO:0007165 signal transduction
1.10 1.37e-03 GO:0009987 cellular process
1.15 3.15e-03 GO:0065007 biological regulation
1.24 7.00e-03 GO:0051716 cellular response to stimulus
1.14 4.95e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 3.08e-06 GO:0005737 cytoplasm
1.16 8.06e-03 GO:0044444 cytoplasmic part
1.31 8.50e-03 GO:0044459 plasma membrane part
1.50 1.21e-02 GO:0042995 cell projection
2.10 3.32e-02 GO:0031252 cell leading edge
1.71 4.53e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 6.45e-04 GO:0005515 protein binding