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Motif ID: bHLH_family.p2

Z-value: 1.245

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_58146110	5.154		CDK4	cyclin-dependent kinase 4
chr12_-_58146118	5.107	NM_000075	CDK4	cyclin-dependent kinase 4
chr12_-_58146025	4.872		CDK4	cyclin-dependent kinase 4
chr12_-_58146108	3.512		CDK4	cyclin-dependent kinase 4
chr11_+_61560401	2.840		FEN1	flap structure-specific endonuclease 1
chr2_-_10588451	2.520	NM_002539	ODC1	ornithine decarboxylase 1
chr17_+_39382878	2.500	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr5_-_172755195	2.319		STC2	stanniocalcin 2
chr11_+_61560352	2.284		FEN1	flap structure-specific endonuclease 1
chr16_+_89778242	1.999		LOC100128881	uncharacterized LOC100128881
chr11_+_61560108	1.988	NM_004111	FEN1	flap structure-specific endonuclease 1
chr3_+_99536667	1.933	NM_032359	C3orf26	chromosome 3 open reading frame 26
chr5_-_172755418	1.883		STC2	stanniocalcin 2
chr2_+_172864803	1.872	NM_199227	METAP1D	methionyl aminopeptidase type 1D (mitochondrial)
chr5_+_150827138	1.860	NM_078483	SLC36A1	solute carrier family 36 (proton/amino acid symporter), member 1
chr2_-_10588273	1.830		ODC1	ornithine decarboxylase 1
chrX_-_100603956	1.789	NM_004085	TIMM8A	translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr17_+_39261640	1.737	NM_001146041	KRTAP4-9	keratin associated protein 4-9
chr1_-_26233367	1.720	NM_203399	STMN1	stathmin 1
chr14_-_20923266	1.686	NM_017807	OSGEP	O-sialoglycoprotein endopeptidase
chr4_-_54232007	1.670	NM_152540	SCFD2	sec1 family domain containing 2
chr7_-_105162551	1.596	NM_019042	PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)
chr1_+_1167622	1.480	NM_080605	B3GALT6	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr1_-_26232643	1.462	NM_203401	STMN1	stathmin 1
chr3_-_49967194	1.433	NM_001142501 NM_032355	MON1A	MON1 homolog A (yeast)
chr11_-_116663106	1.427	NM_001166598 NM_052968	APOA5	apolipoprotein A-V
chr4_-_657424	1.414
chr1_-_109656478	1.387	NM_001122961	C1orf194	chromosome 1 open reading frame 194
chr16_+_23690190	1.366		PLK1	polo-like kinase 1
chr1_-_11120001	1.363		SRM	spermidine synthase
chr9_-_131709783	1.357	NM_014908	DOLK	dolichol kinase
chr5_+_149737296	1.350		TCOF1	Treacher Collins-Franceschetti syndrome 1
chr9_-_135545327	1.343		DDX31	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr6_-_97345747	1.341		NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr14_-_20922969	1.334		OSGEP	O-sialoglycoprotein endopeptidase
chr6_+_41889191	1.299		BYSL	bystin-like
chr16_+_23690160	1.292		PLK1	polo-like kinase 1
chr2_+_216176818	1.291		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr21_-_44299605	1.277		WDR4	WD repeat domain 4
chr7_-_99698993	1.252		MCM7	minichromosome maintenance complex component 7
chr2_+_216176808	1.251		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_-_120980912	1.236		TMEM185B	transmembrane protein 185B
chr17_-_4458618	1.234	NM_001105538 NM_014520	MYBBP1A	MYB binding protein (P160) 1a
chr7_-_99699030	1.215		MCM7	minichromosome maintenance complex component 7
chr14_-_20922841	1.214		OSGEP	O-sialoglycoprotein endopeptidase
chr16_+_23690234	1.212		PLK1	polo-like kinase 1
chr7_-_99698916	1.184		MCM7	minichromosome maintenance complex component 7
chr1_-_11120081	1.149	NM_003132	SRM	spermidine synthase
chr5_+_126112847	1.131		LMNB1	lamin B1
chr16_+_23690191	1.127	NM_005030	PLK1	polo-like kinase 1
chr5_+_110427869	1.091	NM_139281	WDR36	WD repeat domain 36
chr2_+_216176678	1.087	NM_004044	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr5_-_132948222	1.075	NM_015082	FSTL4	follistatin-like 4
chr15_-_83316621	1.067	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr16_-_5083933	1.055	NM_016256	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr18_+_12407894	1.055	NM_001142405 NM_006553	SLMO1	slowmo homolog 1 (Drosophila)
chr8_-_110657025	1.054	NM_001099753 NM_001099754 NM_001099755	SYBU	syntabulin (syntaxin-interacting)
chr3_-_50329702	1.051	NM_006764	IFRD2	interferon-related developmental regulator 2
chr16_-_5083913	1.043		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chrX_-_15872921	1.042		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr1_+_214776494	1.023	NM_016343	CENPF	centromere protein F, 350/400kDa (mitosin)
chr1_+_214776582	1.019		CENPF	centromere protein F, 350/400kDa (mitosin)
chr15_-_68521921	1.011	NM_017882	CLN6	ceroid-lipofuscinosis, neuronal 6, late infantile, variant
chr16_+_23690212	1.003		PLK1	polo-like kinase 1
chr8_+_67341244	0.996	NM_015169	RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr5_+_149340437	0.993		SLC26A2	solute carrier family 26 (sulfate transporter), member 2
chr11_+_118958696	0.989	NM_001024382	HMBS	hydroxymethylbilane synthase
chr17_+_40985444	0.986		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr2_-_71221833	0.985		TEX261	testis expressed 261
chrX_+_16804531	0.983	NM_001168683 NM_018360	TXLNG	taxilin gamma
chrX_+_152908819	0.983		DUSP9	dual specificity phosphatase 9
chr4_+_140222668	0.977	NM_057175	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_-_39280377	0.971	NM_031854	KRTAP4-12	keratin associated protein 4-12
chr9_-_34637623	0.971		SIGMAR1	sigma non-opioid intracellular receptor 1
chr9_+_131709991	0.971		NUP188	nucleoporin 188kDa
chr19_-_41903226	0.970	NM_020158	EXOSC5	exosome component 5
chr19_+_7587436	0.969	NM_020533	MCOLN1	mucolipin 1
chr5_+_149737201	0.968	NM_000356 NM_001008657 NM_001135243 NM_001135244 NM_001135245 NM_001195141	TCOF1	Treacher Collins-Franceschetti syndrome 1
chr9_+_131709970	0.956	NM_015354	NUP188	nucleoporin 188kDa
chr11_+_20409212	0.944		PRMT3	protein arginine methyltransferase 3
chr8_-_126104004	0.937		KIAA0196	KIAA0196
chr16_-_4897265	0.934	NM_032569	GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr2_+_29117503	0.933	NM_015131	WDR43	WD repeat domain 43
chr5_+_149340287	0.929	NM_000112	SLC26A2	solute carrier family 26 (sulfate transporter), member 2
chr3_+_49059046	0.926	NM_199069 NM_199070	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr9_-_33473846	0.923		NOL6	nucleolar protein family 6 (RNA-associated)
chr4_-_57301643	0.920	NM_002703	PPAT	phosphoribosyl pyrophosphate amidotransferase
chr8_+_22224997	0.916	NM_001135153	SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr19_+_50180408	0.915	NM_001207042 NM_001536 NM_198318	PRMT1	protein arginine methyltransferase 1
chr20_+_2633177	0.911	NM_006392	NOP56	NOP56 ribonucleoprotein homolog (yeast)
chr1_-_42921676	0.910		ZMYND12	zinc finger, MYND-type containing 12
chr8_-_126104021	0.904		KIAA0196	KIAA0196
chr2_+_113403433	0.898	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chrX_-_15872882	0.895		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr1_-_36184392	0.894		C1orf216	chromosome 1 open reading frame 216
chr5_-_94620277	0.890	NM_024717	MCTP1	multiple C2 domains, transmembrane 1
chr22_-_42343079	0.887	NM_001002876 NM_024053	CENPM	centromere protein M
chr17_-_39211462	0.886	NM_033032	KRTAP2-2	keratin associated protein 2-2
chr11_+_20409075	0.881	NM_001145166 NM_001145167 NM_005788	PRMT3	protein arginine methyltransferase 3
chr6_-_153304590	0.880	NM_001142522	FBXO5	F-box protein 5
chrX_+_106871739	0.875		PRPS1	phosphoribosyl pyrophosphate synthetase 1
chr8_-_126103926	0.874		KIAA0196	KIAA0196
chr16_-_1525020	0.872		CLCN7	chloride channel 7
chr3_+_49059490	0.866		NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr2_-_219925237	0.864	NM_002181	IHH	Indian hedgehog
chr9_-_130890401	0.855	NM_025072	PTGES2	prostaglandin E synthase 2
chr12_+_54393876	0.852	NM_006897	HOXC9	homeobox C9
chr9_-_33473876	0.843		NOL6	nucleolar protein family 6 (RNA-associated)
chr9_-_33473919	0.835	NM_022917 NM_139235	NOL6	nucleolar protein family 6 (RNA-associated)
chr1_-_53164014	0.832		SELRC1	Sel1 repeat containing 1
chr1_-_52831817	0.831	NM_032449	CC2D1B	coiled-coil and C2 domain containing 1B
chr17_+_72270385	0.823	NM_001172810 NM_023036	DNAI2	dynein, axonemal, intermediate chain 2
chr14_-_24657986	0.818		IPO4	importin 4
chr8_-_126104045	0.811	NM_014846	KIAA0196	KIAA0196
chr17_-_57184034	0.809		TRIM37	tripartite motif containing 37
chr11_+_60223281	0.803	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr10_-_102988688	0.801	NM_006562	LBX1	ladybird homeobox 1
chr1_+_218458628	0.790	NM_016052	RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)
chr19_+_33685140	0.790		LRP3	low density lipoprotein receptor-related protein 3
chr17_+_40985434	0.787		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr14_-_24658010	0.784	NM_024658	IPO4	importin 4
chr6_-_97345676	0.773		NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr11_+_126081618	0.769	NM_024556	FAM118B	family with sequence similarity 118, member B
chrX_-_15872905	0.768
chr7_+_150759633	0.767	NM_001199693 NM_001199694	SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr17_+_46018888	0.765	NM_018129	PNPO	pyridoxamine 5'-phosphate oxidase
chr3_-_49941300	0.764	NM_001244937 NM_002447	MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr6_-_4079390	0.764	NM_173563	C6orf146	chromosome 6 open reading frame 146
chr22_+_19467467	0.762		CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr1_+_89990396	0.761	NM_001134476	LRRC8B	leucine rich repeat containing 8 family, member B
chr1_+_218458646	0.760		RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)
chr6_+_80714389	0.759		TTK	TTK protein kinase
chr5_-_159739482	0.756	NM_024565	CCNJL	cyclin J-like
chr4_+_128651518	0.756	NM_031291	SLC25A31	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr17_-_39203423	0.754	NM_001123387	KRTAP2-1	keratin associated protein 2-1
chr1_+_11333244	0.752	NM_013319	UBIAD1	UbiA prenyltransferase domain containing 1
chrX_+_152770083	0.748		BGN	biglycan
chr22_+_19467413	0.746	NM_001178010 NM_001178011 NM_003504	CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr6_-_97345760	0.745	NM_014165	NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr2_-_120980971	0.742	NM_024121	TMEM185B	transmembrane protein 185B
chr1_-_36184727	0.741	NM_152374	C1orf216	chromosome 1 open reading frame 216
chr15_-_52587851	0.739	NM_018728	MYO5C	myosin VC
chr1_-_212873306	0.738	NM_018664	BATF3	basic leucine zipper transcription factor, ATF-like 3
chr17_+_39405938	0.737	NM_033191	KRTAP9-4	keratin associated protein 9-4
chr5_+_150827204	0.734		SLC36A1	solute carrier family 36 (proton/amino acid symporter), member 1
chr6_+_80714321	0.733	NM_001166691 NM_003318	TTK	TTK protein kinase
chr12_-_85306569	0.732		SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15
chr8_-_126104007	0.730		KIAA0196	KIAA0196
chr9_-_34637752	0.728	NM_005866 NM_147157	SIGMAR1	sigma non-opioid intracellular receptor 1
chr12_-_2986299	0.726	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr19_+_10812111	0.724	NM_031209	QTRT1	queuine tRNA-ribosyltransferase 1
chr12_+_101673895	0.723	NM_014503	UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)
chr3_+_119187782	0.721	NM_152305	POGLUT1	protein O-glucosyltransferase 1
chr5_-_133706717	0.720		CDKL3	cyclin-dependent kinase-like 3
chr9_-_15510899	0.719	NM_001128217 NM_033222	PSIP1	PC4 and SFRS1 interacting protein 1
chr1_-_42921923	0.714	NM_001146192 NM_032257	ZMYND12	zinc finger, MYND-type containing 12
chr4_-_3957141	0.713		FAM86EP	family with sequence similarity 86, member A pseudogene
chr6_+_41888993	0.712		BYSL	bystin-like
chr11_+_63706433	0.705	NM_024771	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr3_-_170626381	0.704		EIF5A2	eukaryotic translation initiation factor 5A2
chr6_+_41888964	0.703	NM_004053	BYSL	bystin-like
chr19_-_14316980	0.702	NM_001008701 NM_014921	LPHN1	latrophilin 1
chr4_+_129732427	0.702		PHF17	PHD finger protein 17
chr3_+_183967469	0.698		ECE2	endothelin converting enzyme 2
chr8_-_126103873	0.696		KIAA0196	KIAA0196
chr15_-_41408329	0.695	NM_017553	INO80	INO80 homolog (S. cerevisiae)
chr17_+_49230929	0.694		NME1	non-metastatic cells 1, protein (NM23A) expressed in
chr19_-_55791490	0.686		HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_+_50180492	0.683		PRMT1	protein arginine methyltransferase 1
chr12_-_2986095	0.681		FOXM1	forkhead box M1
chr1_-_154531083	0.680	NM_017582	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr18_+_56807115	0.678	NM_033280	SEC11C	SEC11 homolog C (S. cerevisiae)
chr1_-_207119707	0.675	NM_002644	PIGR	polymeric immunoglobulin receptor
chr17_+_40985425	0.674		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr8_-_91657739	0.674		TMEM64	transmembrane protein 64
chr10_+_115939018	0.672	NM_198795	TDRD1	tudor domain containing 1
chr1_-_28559513	0.672	NM_014280	DNAJC8	DnaJ (Hsp40) homolog, subfamily C, member 8
chr12_-_104234968	0.669	NM_001031701	NT5DC3	5'-nucleotidase domain containing 3
chr13_+_51483901	0.668		RNASEH2B	ribonuclease H2, subunit B
chr1_+_229761988	0.668		URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr2_-_71221951	0.666		TEX261	testis expressed 261
chrX_+_24712063	0.664	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr8_+_99129488	0.663	NM_001145860 NM_001145861	POP1	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
chr13_+_51483912	0.663		RNASEH2B	ribonuclease H2, subunit B
chr16_+_103827	0.658	NM_024571	SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr6_-_43197178	0.657	NM_006443 NM_199184	C6orf108	chromosome 6 open reading frame 108
chr5_+_141016987	0.654		RELL2	RELT-like 2
chr16_+_103859	0.653		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr9_+_130159383	0.649	NM_014580	SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8
chr22_+_29313376	0.647	NM_032173	ZNRF3	zinc and ring finger 3
chr17_+_49230938	0.647		NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr2_+_203130435	0.645		NOP58	NOP58 ribonucleoprotein homolog (yeast)
chr10_-_120925157	0.644	NM_213649	SFXN4	sideroflexin 4
chr21_-_44299660	0.644	NM_018669 NM_033661	WDR4	WD repeat domain 4
chr16_+_103009	0.643		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr6_-_8102753	0.641	NM_001135650 NM_004280	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1
chr1_-_11120047	0.640		SRM	spermidine synthase
chr9_-_130890026	0.639		PTGES2	prostaglandin E synthase 2
chr12_-_85306539	0.639		SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15
chr19_+_18391252	0.635

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.11	1.82e-12	GO:0009987	cellular process
1.52	2.46e-06	GO:0055085	transmembrane transport
1.23	4.55e-06	GO:0006807	nitrogen compound metabolic process
1.24	7.21e-06	GO:0034641	cellular nitrogen compound metabolic process
1.25	1.94e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	2.92e-05	GO:0044260	cellular macromolecule metabolic process
1.28	3.63e-05	GO:0090304	nucleic acid metabolic process
1.13	3.34e-04	GO:0044238	primary metabolic process
1.51	3.44e-04	GO:0006396	RNA processing
1.80	4.13e-04	GO:0034660	ncRNA metabolic process
2.19	4.77e-04	GO:0042254	ribosome biogenesis
1.15	7.08e-04	GO:0043170	macromolecule metabolic process
1.29	1.04e-03	GO:0016070	RNA metabolic process
1.92	1.11e-03	GO:0034470	ncRNA processing
1.19	1.17e-03	GO:0051179	localization
1.27	1.46e-03	GO:0010467	gene expression
1.12	1.52e-03	GO:0044237	cellular metabolic process
1.11	1.62e-03	GO:0008152	metabolic process
1.20	3.02e-03	GO:0051234	establishment of localization
1.20	3.78e-03	GO:0006810	transport
1.98	9.19e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
2.02	1.33e-02	GO:0006403	RNA localization
1.80	1.57e-02	GO:0022613	ribonucleoprotein complex biogenesis
3.21	1.72e-02	GO:0015682	ferric iron transport
3.21	1.72e-02	GO:0033572	transferrin transport
1.77	1.92e-02	GO:0071843	cellular component biogenesis at cellular level
1.47	2.31e-02	GO:0016071	mRNA metabolic process
1.99	3.55e-02	GO:0050657	nucleic acid transport
1.99	3.55e-02	GO:0050658	RNA transport
1.99	3.55e-02	GO:0051236	establishment of RNA localization
1.58	4.98e-02	GO:0015672	monovalent inorganic cation transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.36	8.34e-12	GO:0031974	membrane-enclosed lumen
1.10	2.45e-11	GO:0005622	intracellular
1.10	3.42e-11	GO:0044424	intracellular part
1.36	5.76e-11	GO:0070013	intracellular organelle lumen
1.40	7.12e-11	GO:0031981	nuclear lumen
1.35	8.83e-11	GO:0043233	organelle lumen
1.36	1.37e-10	GO:0044428	nuclear part
1.73	1.28e-08	GO:0005730	nucleolus
1.17	2.47e-08	GO:0044422	organelle part
1.17	3.26e-08	GO:0044446	intracellular organelle part
1.10	8.41e-08	GO:0043226	organelle
1.10	1.22e-07	GO:0043229	intracellular organelle
1.38	1.22e-06	GO:0005654	nucleoplasm
1.10	2.86e-06	GO:0043227	membrane-bounded organelle
1.10	3.24e-06	GO:0043231	intracellular membrane-bounded organelle
1.11	3.56e-06	GO:0005737	cytoplasm
1.14	8.22e-05	GO:0005634	nucleus
1.19	9.34e-05	GO:0032991	macromolecular complex
1.21	3.86e-04	GO:0043228	non-membrane-bounded organelle
1.21	3.86e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.18	2.04e-03	GO:0043234	protein complex
3.37	5.15e-03	GO:0044452	nucleolar part
1.11	1.29e-02	GO:0044444	cytoplasmic part
4.38	3.55e-02	GO:0005732	small nucleolar ribonucleoprotein complex
1.34	4.22e-02	GO:0031967	organelle envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	4.02e-11	GO:0005515	protein binding
1.07	2.10e-05	GO:0005488	binding
1.36	4.30e-03	GO:0022891	substrate-specific transmembrane transporter activity
1.31	2.46e-02	GO:0022857	transmembrane transporter activity
1.30	2.69e-02	GO:0022892	substrate-specific transporter activity
1.27	3.98e-02	GO:0005215	transporter activity