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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for CUX2

Z-value: 1.17

Motif logo

Transcription factors associated with CUX2

Gene Symbol Gene ID Gene Info
ENSG00000111249.9 cut like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX2hg19_v2_chr12_+_111471828_1114719750.019.7e-01Click!

Activity profile of CUX2 motif

Sorted Z-values of CUX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_100354442 3.94 ENST00000475887.1
G protein-coupled receptor 128
chr7_-_23510086 2.73 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chr1_-_109618566 2.68 ENST00000338366.5
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr2_-_216257849 2.61 ENST00000456923.1
fibronectin 1
chr22_+_38071615 1.95 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr7_+_80231466 1.76 ENST00000309881.7
ENST00000534394.1
CD36 molecule (thrombospondin receptor)
chr19_-_22379753 1.69 ENST00000397121.2
zinc finger protein 676
chr9_+_35673853 1.63 ENST00000378357.4
carbonic anhydrase IX
chr9_+_105757590 1.61 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr8_-_62559366 1.59 ENST00000522919.1
aspartate beta-hydroxylase
chr4_+_69681710 1.53 ENST00000265403.7
ENST00000458688.2
UDP glucuronosyltransferase 2 family, polypeptide B10
chrX_+_55246818 1.44 ENST00000374952.1
P antigen family, member 5 (prostate associated)
chr6_+_151561085 1.39 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr17_+_7942335 1.36 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
arachidonate 15-lipoxygenase, type B
chr16_+_30064411 1.33 ENST00000338110.5
aldolase A, fructose-bisphosphate
chr12_-_10978957 1.33 ENST00000240619.2
taste receptor, type 2, member 10
chr8_-_91095099 1.31 ENST00000265431.3
calbindin 1, 28kDa
chr10_-_90751038 1.29 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr19_+_45409011 1.28 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr19_+_46003056 1.27 ENST00000401593.1
ENST00000396736.2
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr19_-_19729725 1.20 ENST00000251203.9
pre-B-cell leukemia homeobox 4
chr2_+_102456277 1.20 ENST00000421882.1
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_192016316 1.16 ENST00000358470.4
ENST00000432798.1
ENST00000450994.1
signal transducer and activator of transcription 4
chr16_+_30064444 1.14 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
aldolase A, fructose-bisphosphate
chr19_-_4535233 1.14 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr8_+_54764346 1.13 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr10_-_73975657 1.12 ENST00000394919.1
ENST00000526751.1
activating signal cointegrator 1 complex subunit 1
chr1_-_186649543 1.12 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_8378140 1.11 ENST00000377479.2
solute carrier family 45, member 1
chr2_+_95691445 1.10 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
mal, T-cell differentiation protein
chr2_+_95691417 1.10 ENST00000309988.4
mal, T-cell differentiation protein
chr2_+_211342432 1.09 ENST00000430249.2
carbamoyl-phosphate synthase 1, mitochondrial
chr14_-_81425828 1.08 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
centrosomal protein 128kDa
chr10_-_121296045 1.04 ENST00000392865.1
regulator of G-protein signaling 10
chr17_-_53809473 0.92 ENST00000575734.1
transmembrane protein 100
chr12_-_51718436 0.92 ENST00000544402.1
bridging integrator 2
chr6_-_27880174 0.91 ENST00000303324.2
olfactory receptor, family 2, subfamily B, member 2
chr19_+_41882466 0.90 ENST00000436170.2
transmembrane protein 91
chr13_-_46756351 0.89 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr22_+_45148432 0.88 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
Rho GTPase activating protein 8
chrX_-_107682702 0.88 ENST00000372216.4
collagen, type IV, alpha 6
chr9_+_125133315 0.87 ENST00000223423.4
ENST00000362012.2
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_131321863 0.87 ENST00000528282.1
erythrocyte membrane protein band 4.1-like 2
chr2_-_187713891 0.85 ENST00000295131.2
zinc finger, SWIM-type containing 2
chr19_+_7011509 0.84 ENST00000377296.3
Uncharacterized protein
chr17_-_39526052 0.84 ENST00000251646.3
keratin 33B
chr4_+_69962185 0.84 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr3_+_8543393 0.84 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr4_+_69962212 0.82 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_-_90756769 0.82 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr19_+_48216600 0.82 ENST00000263277.3
ENST00000538399.1
EH-domain containing 2
chr6_+_26273144 0.81 ENST00000377733.2
histone cluster 1, H2bi
chr3_+_26735991 0.81 ENST00000456208.2
leucine rich repeat containing 3B
chr19_+_15052301 0.80 ENST00000248072.3
olfactory receptor, family 7, subfamily C, member 2
chr13_-_46679185 0.80 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr1_-_54303949 0.78 ENST00000234725.8
NDC1 transmembrane nucleoporin
chr1_-_54303934 0.77 ENST00000537333.1
NDC1 transmembrane nucleoporin
chr6_+_121756809 0.76 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr15_+_40674963 0.76 ENST00000448395.2
kinetochore-localized astrin/SPAG5 binding protein
chr4_-_100575781 0.76 ENST00000511828.1
Protein LOC285556
chr15_+_40674920 0.76 ENST00000416151.2
ENST00000249776.8
kinetochore-localized astrin/SPAG5 binding protein
chr4_+_70916119 0.75 ENST00000246896.3
ENST00000511674.1
histatin 1
chr17_+_56315936 0.75 ENST00000543544.1
lactoperoxidase
chr19_+_41882598 0.74 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr11_+_35201826 0.74 ENST00000531873.1
CD44 molecule (Indian blood group)
chr4_+_109571740 0.73 ENST00000361564.4
oligosaccharyltransferase complex subunit (non-catalytic)
chr4_+_74275057 0.73 ENST00000511370.1
albumin
chr4_+_71200681 0.72 ENST00000273936.5
calcium-binding protein, spermatid-specific 1
chr5_-_146302078 0.72 ENST00000508545.2
protein phosphatase 2, regulatory subunit B, beta
chr12_+_31226779 0.72 ENST00000542838.1
ENST00000407793.2
ENST00000251758.5
ENST00000228264.6
ENST00000438391.2
ENST00000415475.2
ENST00000545668.1
ENST00000350437.4
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr10_+_6779326 0.72 ENST00000417112.1
RP11-554I8.2
chr3_+_130650738 0.70 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chr3_-_165555200 0.69 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr19_-_7040190 0.69 ENST00000381394.4
methyl-CpG binding domain protein 3-like 4
chrX_-_47489244 0.68 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
complement factor properdin
chr3_+_44916098 0.68 ENST00000296125.4
transglutaminase 4
chr19_+_7030589 0.68 ENST00000329753.5
methyl-CpG binding domain protein 3-like 5
chr1_-_146068184 0.67 ENST00000604894.1
ENST00000369323.3
ENST00000479926.2
neuroblastoma breakpoint family, member 11
chr13_-_46679144 0.66 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr14_-_64194745 0.66 ENST00000247225.6
sphingosine-1-phosphate phosphatase 1
chr11_+_44117099 0.66 ENST00000533608.1
exostosin glycosyltransferase 2
chr11_+_57365150 0.65 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr2_+_120687335 0.65 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr5_-_16742330 0.65 ENST00000505695.1
ENST00000427430.2
myosin X
chr6_-_131277510 0.65 ENST00000525193.1
ENST00000527659.1
erythrocyte membrane protein band 4.1-like 2
chr6_-_27114577 0.65 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr3_-_172859017 0.63 ENST00000351008.3
spermatogenesis associated 16
chr3_+_157827841 0.63 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
arginine/serine-rich coiled-coil 1
chr12_-_89413456 0.63 ENST00000500381.2
RP11-13A1.1
chr22_-_29949680 0.63 ENST00000397873.2
ENST00000490103.1
THO complex 5
chr1_-_197036364 0.63 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr2_+_102413726 0.63 ENST00000350878.4
mitogen-activated protein kinase kinase kinase kinase 4
chr5_+_173472607 0.62 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr11_+_44117260 0.62 ENST00000358681.4
exostosin glycosyltransferase 2
chr17_-_64216748 0.62 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_13910479 0.61 ENST00000509009.1
podoplanin
chr19_-_49243845 0.61 ENST00000222145.4
Ras interacting protein 1
chr1_-_100231349 0.61 ENST00000287474.5
ENST00000414213.1
ferric-chelate reductase 1
chr4_+_70796784 0.60 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr16_+_16326352 0.60 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
NODAL modulator 3
chr6_+_31105426 0.60 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr5_+_162887556 0.59 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
hyaluronan-mediated motility receptor (RHAMM)
chr1_+_16083154 0.59 ENST00000375771.1
filamin binding LIM protein 1
chr1_-_151804314 0.59 ENST00000318247.6
RAR-related orphan receptor C
chr11_+_55578854 0.59 ENST00000333973.2
olfactory receptor, family 5, subfamily L, member 1
chr5_+_60933634 0.58 ENST00000505642.1
chromosome 5 open reading frame 64
chr16_-_18573396 0.58 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NODAL modulator 2
chr12_+_15475331 0.58 ENST00000281171.4
protein tyrosine phosphatase, receptor type, O
chr20_+_62492566 0.57 ENST00000369916.3
abhydrolase domain containing 16B
chr11_+_5410607 0.56 ENST00000328611.3
olfactory receptor, family 51, subfamily M, member 1
chr12_+_43086018 0.56 ENST00000550177.1
RP11-25I15.3
chr2_+_211421262 0.56 ENST00000233072.5
carbamoyl-phosphate synthase 1, mitochondrial
chr2_+_133874577 0.55 ENST00000596384.1
HCG2006742; Protein LOC100996685
chr7_-_36764142 0.54 ENST00000258749.5
ENST00000535891.1
acyloxyacyl hydrolase (neutrophil)
chr16_-_69788816 0.54 ENST00000268802.5
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr1_-_147610081 0.54 ENST00000369226.3
neuroblastoma breakpoint family, member 24
chr18_+_45778672 0.54 ENST00000600091.1
HCG1818186; Uncharacterized protein
chr4_-_159956333 0.54 ENST00000434826.2
chromosome 4 open reading frame 45
chr5_-_11589131 0.54 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr5_-_180665195 0.53 ENST00000509148.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr10_+_5238793 0.53 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr1_-_13052998 0.53 ENST00000436041.1
Uncharacterized protein
chr2_+_102953608 0.53 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr1_+_87458692 0.53 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr1_+_155179012 0.53 ENST00000609421.1
metaxin 1
chr11_+_62623544 0.52 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chrX_+_85969626 0.52 ENST00000484479.1
dachshund homolog 2 (Drosophila)
chr4_+_71587669 0.52 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr4_+_187187098 0.52 ENST00000403665.2
ENST00000264692.4
coagulation factor XI
chr11_-_89653576 0.52 ENST00000420869.1
tripartite motif containing 49D1
chr22_-_50523760 0.51 ENST00000395876.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr19_-_13710678 0.51 ENST00000592864.1
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr8_-_124037890 0.51 ENST00000519018.1
ENST00000523036.1
derlin 1
chr1_-_85097431 0.50 ENST00000327308.3
chromosome 1 open reading frame 180
chr11_+_18230685 0.50 ENST00000340135.3
ENST00000534640.1
Putative mitochondrial carrier protein LOC494141
chr1_-_151804222 0.50 ENST00000392697.3
RAR-related orphan receptor C
chr2_-_214016314 0.50 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr19_-_52674896 0.50 ENST00000322146.8
ENST00000597065.1
zinc finger protein 836
chr3_+_159557637 0.50 ENST00000445224.2
schwannomin interacting protein 1
chr20_-_43150601 0.49 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr3_+_136676851 0.49 ENST00000309741.5
interleukin 20 receptor beta
chr3_+_122785895 0.49 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr12_+_26348429 0.49 ENST00000242729.2
sarcospan
chr17_+_68071389 0.49 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr5_-_156390230 0.49 ENST00000407087.3
ENST00000274532.2
T-cell immunoglobulin and mucin domain containing 4
chr1_-_54304212 0.48 ENST00000540001.1
NDC1 transmembrane nucleoporin
chr4_-_10686475 0.48 ENST00000226951.6
cytokine-dependent hematopoietic cell linker
chr1_+_115572415 0.48 ENST00000256592.1
thyroid stimulating hormone, beta
chr3_+_35682913 0.48 ENST00000449196.1
cAMP-regulated phosphoprotein, 21kDa
chr12_+_100041527 0.47 ENST00000324341.1
family with sequence similarity 71, member C
chr1_+_45265897 0.47 ENST00000372201.4
polo-like kinase 3
chr1_-_110933611 0.47 ENST00000472422.2
ENST00000437429.2
solute carrier family 16, member 4
chr12_-_122879969 0.47 ENST00000540304.1
CAP-GLY domain containing linker protein 1
chr8_+_110098850 0.46 ENST00000518632.1
thyrotropin-releasing hormone receptor
chr1_+_57320437 0.46 ENST00000361249.3
complement component 8, alpha polypeptide
chr22_+_24198890 0.46 ENST00000345044.6
solute carrier family 2 (facilitated glucose transporter), member 11
chr8_+_71485681 0.46 ENST00000391684.1
AC120194.1
chr1_+_144146808 0.46 ENST00000369190.5
ENST00000412624.2
ENST00000369365.3
neuroblastoma breakpoint family, member 8
chr7_-_92777606 0.46 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chrX_+_54947229 0.45 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
trophinin
chr3_+_136676707 0.45 ENST00000329582.4
interleukin 20 receptor beta
chr5_-_115910630 0.45 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_-_11588907 0.44 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr20_-_45142154 0.44 ENST00000347606.4
ENST00000457685.2
zinc finger protein 334
chr1_-_110933663 0.44 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
solute carrier family 16, member 4
chr6_+_106534192 0.44 ENST00000369091.2
ENST00000369096.4
PR domain containing 1, with ZNF domain
chr12_-_64784471 0.43 ENST00000333722.5
chromosome 12 open reading frame 56
chr21_+_43619796 0.43 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr1_+_196743912 0.43 ENST00000367425.4
complement factor H-related 3
chr4_-_143227088 0.43 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_+_15341442 0.43 ENST00000397700.2
ENST00000295297.4
C1q and tumor necrosis factor related protein 7
chrX_-_65253506 0.43 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr11_+_55944094 0.42 ENST00000312298.1
olfactory receptor, family 5, subfamily J, member 2
chr1_+_145293371 0.42 ENST00000342960.5
neuroblastoma breakpoint family, member 10
chr12_+_26348246 0.42 ENST00000422622.2
sarcospan
chr3_+_157828152 0.42 ENST00000476899.1
arginine/serine-rich coiled-coil 1
chr19_+_48248779 0.42 ENST00000246802.5
glioma tumor suppressor candidate region gene 2
chrX_+_11311533 0.42 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
amelogenin, X-linked
chr11_-_35547151 0.41 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
peptidase domain containing associated with muscle regeneration 1
chr16_+_446713 0.41 ENST00000397722.1
ENST00000454619.1
NME/NM23 nucleoside diphosphate kinase 4
chr15_-_64673665 0.41 ENST00000300035.4
KIAA0101
chr4_+_174818390 0.41 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
chr8_-_110986918 0.41 ENST00000297404.1
potassium channel, subfamily V, member 1
chr2_+_90077680 0.41 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr5_-_101834617 0.41 ENST00000513675.1
ENST00000379807.3
solute carrier organic anion transporter family, member 6A1
chr12_-_10605929 0.41 ENST00000347831.5
ENST00000359151.3
killer cell lectin-like receptor subfamily C, member 1
chr17_+_3118915 0.41 ENST00000304094.1
olfactory receptor, family 1, subfamily A, member 1
chr3_+_130279178 0.40 ENST00000358511.6
ENST00000453409.2
collagen, type VI, alpha 6
chr2_-_228497888 0.40 ENST00000264387.4
ENST00000409066.1
chromosome 2 open reading frame 83
chr9_-_21187598 0.40 ENST00000421715.1
interferon, alpha 4
chr11_+_60260248 0.40 ENST00000526784.1
ENST00000016913.4
ENST00000537076.1
ENST00000530007.1
membrane-spanning 4-domains, subfamily A, member 12
chr2_+_48796120 0.40 ENST00000394754.1
STON1-GTF2A1L readthrough
chr18_-_70532906 0.40 ENST00000299430.2
ENST00000397929.1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_+_1727755 0.40 ENST00000424383.2
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr4_+_90800656 0.39 ENST00000394980.1
multimerin 1
chr10_+_70980051 0.39 ENST00000354624.5
ENST00000395086.2
hexokinase domain containing 1
chr4_-_70826725 0.39 ENST00000353151.3
casein beta
chr2_+_58655461 0.39 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr9_+_71939488 0.39 ENST00000455972.1
family with sequence similarity 189, member A2
chr19_+_507299 0.39 ENST00000359315.5
tubulin polyglutamylase complex subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.7 2.0 GO:0071789 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.4 1.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.3 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.4 1.6 GO:0071400 cellular response to oleic acid(GO:0071400)
0.4 0.4 GO:1903487 regulation of lactation(GO:1903487)
0.4 1.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 1.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 1.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 1.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3 1.0 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3 0.8 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.3 1.8 GO:0072564 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.7 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 0.9 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 0.7 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.9 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 2.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.7 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 0.8 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.5 GO:2000777 endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 1.3 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.7 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1 0.4 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.1 2.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.8 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:0060356 leucine import(GO:0060356)
0.1 0.9 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 1.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.4 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.2 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 0.3 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.8 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 1.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.5 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 1.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 2.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.5 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.7 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 1.6 GO:0036315 cellular response to sterol(GO:0036315)
0.1 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.1 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0098907 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) regulation of AV node cell action potential(GO:0098904) regulation of SA node cell action potential(GO:0098907)
0.1 0.3 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.2 GO:1902725 trans-synaptic signaling by trans-synaptic complex(GO:0099545) negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 1.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 4.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 1.0 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.9 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 1.4 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 2.5 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.9 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.5 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 1.4 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.2 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.6 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.5 1.6 GO:0033150 cytoskeletal calyx(GO:0033150)
0.4 1.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 2.9 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 1.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.5 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 0.4 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.4 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.5 GO:0008091 spectrin(GO:0008091)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 2.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.6 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 2.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 4.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 2.9 GO:0043679 axon terminus(GO:0043679)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.5 1.6 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.5 2.5 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.5 1.9 GO:0030395 lactose binding(GO:0030395)
0.3 1.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 1.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3 1.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 0.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 1.3 GO:0005499 vitamin D binding(GO:0005499)
0.2 1.8 GO:0004111 creatine kinase activity(GO:0004111)
0.2 2.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.1 GO:0035473 lipase binding(GO:0035473)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.5 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 2.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 1.1 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 3.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 1.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 1.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 1.3 GO:0005549 odorant binding(GO:0005549)
0.1 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 2.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 2.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 3.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.7 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 1.1 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.4 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 2.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 3.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 5.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 3.3 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators