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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXC9

Z-value: 0.59

Motif logo

Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
ENSG00000180806.4 homeobox C9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC9hg19_v2_chr12_+_54393880_54393962-0.346.5e-02Click!

Activity profile of HOXC9 motif

Sorted Z-values of HOXC9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_25055177 1.17 ENST00000538118.1
branched chain amino-acid transaminase 1, cytosolic
chr2_-_216878305 0.97 ENST00000263268.6
melanoregulin
chr11_+_125496400 0.91 ENST00000524737.1
checkpoint kinase 1
chr18_+_34124507 0.84 ENST00000591635.1
formin homology 2 domain containing 3
chr1_-_197115818 0.80 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr8_+_94241867 0.77 ENST00000598428.1
Uncharacterized protein
chr14_+_31046959 0.75 ENST00000547532.1
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr7_+_138915102 0.73 ENST00000486663.1
ubinuclein 2
chr11_+_125496619 0.70 ENST00000532669.1
ENST00000278916.3
checkpoint kinase 1
chr7_+_130126165 0.70 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chr12_-_30887948 0.68 ENST00000433722.2
caprin family member 2
chr7_+_130126012 0.68 ENST00000341441.5
mesoderm specific transcript
chr12_-_95945246 0.66 ENST00000258499.3
ubiquitin specific peptidase 44
chr13_-_24007815 0.64 ENST00000382298.3
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr3_+_149191723 0.62 ENST00000305354.4
transmembrane 4 L six family member 4
chr11_-_107729887 0.61 ENST00000525815.1
solute carrier family 35, member F2
chr19_-_47975417 0.59 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_-_113478603 0.59 ENST00000443580.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr7_-_41742697 0.57 ENST00000242208.4
inhibin, beta A
chr22_-_32767017 0.56 ENST00000400234.1
RFPL3 antisense
chr10_+_5238793 0.54 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr4_-_69111401 0.53 ENST00000332644.5
transmembrane protease, serine 11B
chr11_+_125496124 0.53 ENST00000533778.2
ENST00000534070.1
checkpoint kinase 1
chr18_-_19994830 0.52 ENST00000525417.1
cutaneous T-cell lymphoma-associated antigen 1
chr3_-_108672609 0.51 ENST00000393963.3
ENST00000471108.1
guanylate cyclase activator 1C
chr21_-_31859755 0.51 ENST00000334055.3
keratin associated protein 19-2
chr11_-_5323226 0.50 ENST00000380224.1
olfactory receptor, family 51, subfamily B, member 4
chr4_-_156787425 0.50 ENST00000537611.2
acid-sensing (proton-gated) ion channel family member 5
chr17_-_39254391 0.48 ENST00000333822.4
keratin associated protein 4-8
chr10_+_76871229 0.47 ENST00000372690.3
sterile alpha motif domain containing 8
chr2_+_48541776 0.47 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr2_+_108994466 0.45 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr2_+_108994633 0.45 ENST00000409309.3
sulfotransferase family, cytosolic, 1C, member 4
chr19_-_48753064 0.45 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
caspase recruitment domain family, member 8
chr15_+_52155001 0.44 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chr3_+_122785895 0.44 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr15_+_40987327 0.43 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51 recombinase
chr7_+_141811539 0.43 ENST00000550469.2
ENST00000477922.3
Putative inactive maltase-glucoamylase-like protein LOC93432
chr12_+_113354341 0.42 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_76871353 0.42 ENST00000542569.1
sterile alpha motif domain containing 8
chr19_-_48759119 0.42 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
caspase recruitment domain family, member 8
chr2_+_37571845 0.41 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr2_+_37571717 0.41 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr12_+_104235229 0.41 ENST00000551650.1
Uncharacterized protein
chr11_+_89764274 0.41 ENST00000448984.1
ENST00000432771.1
tripartite motif containing 49C
chr2_+_158114051 0.40 ENST00000259056.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr3_-_108672742 0.40 ENST00000261047.3
guanylate cyclase activator 1C
chr14_+_57671888 0.40 ENST00000391612.1
AL391152.1
chr16_-_74734672 0.40 ENST00000306247.7
ENST00000575686.1
mixed lineage kinase domain-like
chr1_+_244515930 0.39 ENST00000366537.1
ENST00000308105.4
chromosome 1 open reading frame 100
chr2_+_210444142 0.38 ENST00000360351.4
ENST00000361559.4
microtubule-associated protein 2
chr19_+_55014013 0.38 ENST00000301202.2
leukocyte-associated immunoglobulin-like receptor 2
chrX_+_43515467 0.38 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr19_+_55014085 0.37 ENST00000351841.2
leukocyte-associated immunoglobulin-like receptor 2
chr5_-_16738451 0.37 ENST00000274203.9
ENST00000515803.1
myosin X
chr11_-_89541743 0.36 ENST00000329758.1
tripartite motif containing 49
chr1_+_178694300 0.36 ENST00000367635.3
Ral GEF with PH domain and SH3 binding motif 2
chr1_-_173176452 0.35 ENST00000281834.3
tumor necrosis factor (ligand) superfamily, member 4
chr16_-_74734742 0.35 ENST00000308807.7
ENST00000573267.1
mixed lineage kinase domain-like
chr11_-_114466471 0.35 ENST00000424261.2
neurexophilin and PC-esterase domain family, member 4
chr18_-_12656715 0.35 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
spire-type actin nucleation factor 1
chr1_+_192127578 0.35 ENST00000367460.3
regulator of G-protein signaling 18
chr9_+_80912059 0.34 ENST00000347159.2
ENST00000376588.3
phosphoserine aminotransferase 1
chr13_-_36050819 0.34 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr9_+_77112244 0.34 ENST00000376896.3
RAR-related orphan receptor B
chr2_-_17981462 0.33 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr19_+_16940198 0.33 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3 transcription regulator family member B
chr4_+_70916119 0.32 ENST00000246896.3
ENST00000511674.1
histatin 1
chr12_+_75874580 0.31 ENST00000456650.3
GLI pathogenesis-related 1
chr2_-_208031943 0.31 ENST00000421199.1
ENST00000457962.1
Kruppel-like factor 7 (ubiquitous)
chr12_-_8803128 0.30 ENST00000543467.1
microfibrillar associated protein 5
chr18_+_44812072 0.30 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
chr2_+_161993465 0.30 ENST00000457476.1
TRAF family member-associated NFKB activator
chr18_+_22040620 0.30 ENST00000426880.2
histamine receptor H4
chr21_-_31869451 0.30 ENST00000334058.2
keratin associated protein 19-4
chr11_-_55703876 0.29 ENST00000301532.3
olfactory receptor, family 5, subfamily I, member 1
chr5_-_16916624 0.29 ENST00000513882.1
myosin X
chr6_-_26189304 0.29 ENST00000340756.2
histone cluster 1, H4d
chr4_-_39979576 0.29 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr6_+_130339710 0.29 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr2_+_162016827 0.28 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr15_+_26360970 0.28 ENST00000556159.1
ENST00000557523.1
long intergenic non-protein coding RNA 929
chr5_-_125930929 0.28 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr13_-_52027134 0.28 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr22_-_32766972 0.28 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr13_-_33760216 0.28 ENST00000255486.4
StAR-related lipid transfer (START) domain containing 13
chr18_+_12407895 0.27 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
slowmo homolog 1 (Drosophila)
chr10_+_32873190 0.27 ENST00000375025.4
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr4_+_56814968 0.27 ENST00000422247.2
centrosomal protein 135kDa
chr18_+_29027696 0.27 ENST00000257189.4
desmoglein 3
chr19_-_48753028 0.27 ENST00000522431.1
caspase recruitment domain family, member 8
chr2_-_134326009 0.26 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr1_-_204183071 0.25 ENST00000308302.3
golgi transport 1A
chr17_-_39306054 0.25 ENST00000343246.4
keratin associated protein 4-5
chr22_+_22676808 0.25 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr2_+_143635222 0.25 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr4_-_119759795 0.24 ENST00000419654.2
SEC24 family member D
chr4_+_71600144 0.24 ENST00000502653.1
RUN and FYVE domain containing 3
chr8_-_81083731 0.24 ENST00000379096.5
tumor protein D52
chr19_+_9296279 0.24 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr15_-_55541227 0.24 ENST00000566877.1
RAB27A, member RAS oncogene family
chr17_-_9694614 0.23 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr19_-_54850417 0.23 ENST00000291759.4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
chr1_-_158656488 0.23 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr3_+_50606901 0.23 ENST00000455834.1
HemK methyltransferase family member 1
chr4_+_123844225 0.23 ENST00000274008.4
spermatogenesis associated 5
chr7_-_22539771 0.23 ENST00000406890.2
ENST00000424363.1
STEAP family member 1B
chr6_+_13272904 0.22 ENST00000379335.3
ENST00000379329.1
phosphatase and actin regulator 1
chr7_+_110731062 0.22 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr15_-_41836441 0.22 ENST00000567866.1
ENST00000561603.1
ENST00000304330.4
ENST00000566863.1
RNA polymerase II associated protein 1
chr14_-_57272366 0.21 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
orthodenticle homeobox 2
chr14_+_73706308 0.21 ENST00000554301.1
ENST00000555445.1
papilin, proteoglycan-like sulfated glycoprotein
chr4_+_106631966 0.21 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr2_-_169887827 0.21 ENST00000263817.6
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr18_-_59274139 0.21 ENST00000586949.1
RP11-879F14.2
chr8_-_81083890 0.21 ENST00000518937.1
tumor protein D52
chr1_+_151735431 0.21 ENST00000321531.5
ENST00000315067.8
ornithine decarboxylase antizyme 3
chr17_-_9862772 0.20 ENST00000580865.1
ENST00000583882.1
growth arrest-specific 7
chr1_-_19426149 0.20 ENST00000429347.2
ubiquitin protein ligase E3 component n-recognin 4
chrX_+_153775821 0.20 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr17_-_39324424 0.20 ENST00000391356.2
keratin associated protein 4-3
chr17_-_39646116 0.19 ENST00000328119.6
keratin 36
chr1_-_47069955 0.19 ENST00000341183.5
ENST00000496619.1
MAP kinase interacting serine/threonine kinase 1
chr22_-_27456361 0.19 ENST00000453934.1
CTA-992D9.6
chr17_+_67498538 0.19 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr7_-_113559104 0.19 ENST00000284601.3
protein phosphatase 1, regulatory subunit 3A
chr3_-_48130707 0.19 ENST00000360240.6
ENST00000383737.4
microtubule-associated protein 4
chrX_+_15525426 0.19 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr2_+_105050794 0.19 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr12_-_31743901 0.18 ENST00000354285.4
DENN/MADD domain containing 5B
chr15_-_76304731 0.18 ENST00000394907.3
neuregulin 4
chr22_-_24126145 0.18 ENST00000598975.1
Uncharacterized protein
chr17_+_33914276 0.18 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr11_-_114430570 0.18 ENST00000251921.2
neurexophilin and PC-esterase domain family, member 1
chr4_+_88529681 0.18 ENST00000399271.1
dentin sialophosphoprotein
chr12_-_52828147 0.18 ENST00000252245.5
keratin 75
chr19_-_41985048 0.17 ENST00000599801.1
ENST00000595063.1
ENST00000598215.1
AC011526.1
chr6_+_28249299 0.17 ENST00000405948.2
piggyBac transposable element derived 1
chr3_-_170588163 0.17 ENST00000295830.8
ribosomal protein L22-like 1
chr10_-_96829246 0.17 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr14_+_72399833 0.17 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr16_-_56553882 0.17 ENST00000568104.1
Bardet-Biedl syndrome 2
chr17_+_76494911 0.17 ENST00000598378.1
DNAH17 antisense RNA 1
chr20_+_36373032 0.17 ENST00000373473.1
catenin, beta like 1
chr8_+_66955648 0.16 ENST00000522619.1
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr6_+_28249332 0.16 ENST00000259883.3
piggyBac transposable element derived 1
chr11_+_19798964 0.16 ENST00000527559.2
neuron navigator 2
chr12_-_27167233 0.16 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
transmembrane 7 superfamily member 3
chr4_+_56815102 0.16 ENST00000257287.4
centrosomal protein 135kDa
chr15_-_90222642 0.16 ENST00000430628.2
perilipin 1
chr15_-_90222610 0.16 ENST00000300055.5
perilipin 1
chr8_-_93029865 0.16 ENST00000422361.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_21187598 0.16 ENST00000421715.1
interferon, alpha 4
chr10_-_71169031 0.15 ENST00000373307.1
tachykinin receptor 2
chr2_+_161993412 0.15 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr2_+_202047596 0.15 ENST00000286186.6
ENST00000360132.3
caspase 10, apoptosis-related cysteine peptidase
chr2_-_105030466 0.15 ENST00000449772.1
AC068535.3
chr3_+_87276407 0.15 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
charged multivesicular body protein 2B
chr20_+_68306 0.15 ENST00000382410.2
defensin, beta 125
chr11_+_73498898 0.15 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
mitochondrial ribosomal protein L48
chr7_+_80275752 0.15 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr7_+_80275953 0.15 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr3_+_97887544 0.14 ENST00000356526.2
olfactory receptor, family 5, subfamily H, member 15
chr14_+_67291158 0.14 ENST00000555456.1
gephyrin
chr4_-_69536346 0.14 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr17_-_72772462 0.14 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr2_+_219472488 0.14 ENST00000450993.2
phospholipase C, delta 4
chr6_-_22297730 0.14 ENST00000306482.1
prolactin
chr7_-_44122063 0.14 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
polymerase (DNA directed), mu
chr2_-_200715834 0.14 ENST00000420128.1
ENST00000416668.1
formiminotransferase cyclodeaminase N-terminal like
chr3_+_112709804 0.14 ENST00000383677.3
GTP-binding protein 8 (putative)
chr14_+_22386325 0.13 ENST00000390439.2
T cell receptor alpha variable 13-2
chr1_+_96457545 0.13 ENST00000413825.2
Uncharacterized protein
chr9_-_98079965 0.13 ENST00000289081.3
Fanconi anemia, complementation group C
chr3_+_16306691 0.13 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
oxidoreductase NAD-binding domain containing 1
chr6_+_47749718 0.13 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
opsin 5
chr1_+_22962948 0.13 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr2_+_233390890 0.13 ENST00000258385.3
ENST00000536614.1
ENST00000457943.2
cholinergic receptor, nicotinic, delta (muscle)
chr10_+_78078088 0.13 ENST00000496424.2
chromosome 10 open reading frame 11
chrX_-_9734004 0.13 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr1_-_7913089 0.13 ENST00000361696.5
urotensin 2
chr1_+_32379174 0.12 ENST00000391369.1
HCG2032337; PRO1848; Uncharacterized protein
chr3_+_16306837 0.12 ENST00000606098.1
oxidoreductase NAD-binding domain containing 1
chr12_-_104234966 0.12 ENST00000392876.3
5'-nucleotidase domain containing 3
chr1_+_40506392 0.12 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr1_-_622053 0.12 ENST00000332831.2
olfactory receptor, family 4, subfamily F, member 16
chr15_-_20193370 0.12 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr9_-_95055956 0.12 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chr9_-_95056010 0.12 ENST00000443024.2
isoleucyl-tRNA synthetase
chr4_+_71248795 0.12 ENST00000304915.3
submaxillary gland androgen regulated protein 3B
chr2_-_200715573 0.12 ENST00000420922.2
formiminotransferase cyclodeaminase N-terminal like
chrX_-_119077695 0.11 ENST00000371410.3
NFKB activating protein
chr1_-_226926864 0.11 ENST00000429204.1
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr2_+_162016804 0.11 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator
chr5_+_61874562 0.11 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr6_+_29079668 0.11 ENST00000377169.1
olfactory receptor, family 2, subfamily J, member 3
chr15_+_43425672 0.11 ENST00000260403.2
transmembrane protein 62
chr2_+_162016916 0.11 ENST00000405852.1
TRAF family member-associated NFKB activator
chr7_+_80275621 0.11 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr12_-_11091862 0.11 ENST00000537503.1
taste receptor, type 2, member 14

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 0.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.3 0.8 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 0.6 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2 1.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.6 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 1.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.3 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.4 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 1.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.1 0.4 GO:0072564 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.3 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.0 1.0 GO:0032402 melanosome transport(GO:0032402)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.7 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 1.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 2.4 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0030849 Y chromosome(GO:0000806) autosome(GO:0030849)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.8 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 2.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 0.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 0.6 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 1.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.1 GO:0032089 NACHT domain binding(GO:0032089)
0.2 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators