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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NR4A2

Z-value: 0.51

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Transcription factors associated with NR4A2

Gene Symbol Gene ID Gene Info
NR4A2
ENSG00000153234.9 nuclear receptor subfamily 4 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A2hg19_v2_chr2_-_157198860_1571989780.719.4e-06Click!

Activity profile of NR4A2 motif

Sorted Z-values of NR4A2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_67427389 2.97 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3
tubulin polymerization-promoting protein family member 3
chr5_-_149792295 2.91 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr2_+_120189422 2.05 ENST00000306406.4
TMEM37
transmembrane protein 37
chr1_-_104238912 1.54 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr1_-_104239076 1.51 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr20_+_31755934 1.37 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr4_+_41614909 1.14 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr19_+_35629702 1.01 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr2_-_27712583 0.95 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr4_+_15471489 0.93 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
CC2D2A
coiled-coil and C2 domain containing 2A
chr22_+_32149927 0.81 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5
DEP domain containing 5
chr22_-_27620603 0.80 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
RP5-1172A22.1
chr6_+_149068464 0.78 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr12_-_81992111 0.77 ENST00000443686.3
ENST00000407050.4
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr10_+_81107271 0.71 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr22_-_37880543 0.66 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_41614720 0.61 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr11_+_66624527 0.61 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_-_226129083 0.60 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr1_-_226129189 0.59 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr1_+_196621156 0.57 ENST00000359637.2
CFH
complement factor H
chr14_+_21498666 0.54 ENST00000481535.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr1_+_9648921 0.52 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
TMEM201
transmembrane protein 201
chr20_+_58179582 0.50 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr22_+_31518938 0.50 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr18_-_12377283 0.50 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr14_-_61190754 0.49 ENST00000216513.4
SIX4
SIX homeobox 4
chr10_+_81107216 0.47 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr16_-_28937027 0.45 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr14_-_21492251 0.44 ENST00000554398.1
NDRG2
NDRG family member 2
chr14_-_21492113 0.43 ENST00000554094.1
NDRG2
NDRG family member 2
chr22_-_24110063 0.42 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr9_+_115983808 0.42 ENST00000374210.6
ENST00000374212.4
SLC31A1
solute carrier family 31 (copper transporter), member 1
chr5_-_169626104 0.40 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
CTB-27N1.1
chr5_+_149569520 0.39 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chr8_+_21911054 0.39 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr13_+_97928395 0.38 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr16_-_28936493 0.37 ENST00000544477.1
ENST00000357573.6
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr2_+_219135115 0.37 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr9_+_95997205 0.37 ENST00000411624.1
WNK2
WNK lysine deficient protein kinase 2
chrX_+_13587712 0.37 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr1_-_20141763 0.37 ENST00000375121.2
RNF186
ring finger protein 186
chr14_+_21498360 0.36 ENST00000321760.6
ENST00000460647.2
ENST00000530140.2
ENST00000472458.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr2_+_191334212 0.36 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr10_-_50970382 0.35 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr1_+_16062820 0.34 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr2_-_220110111 0.34 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L
galactosidase, beta 1-like
chr14_-_24911868 0.34 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr10_-_50970322 0.34 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr7_-_72936608 0.33 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr16_+_691792 0.33 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr1_+_196621002 0.33 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr6_+_107077435 0.33 ENST00000369046.4
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr2_-_207024233 0.33 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr20_+_37590942 0.29 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr16_-_4466565 0.28 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr3_+_52813932 0.28 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr7_-_150777874 0.27 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr22_+_51176624 0.27 ENST00000216139.5
ENST00000529621.1
ACR
acrosin
chr2_-_25194963 0.26 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr22_+_30163340 0.25 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr11_-_64511789 0.25 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_-_30457048 0.25 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr1_-_20126365 0.25 ENST00000294543.6
ENST00000375122.2
TMCO4
transmembrane and coiled-coil domains 4
chr22_+_23213658 0.24 ENST00000390318.2
IGLV4-3
immunoglobulin lambda variable 4-3
chr17_-_1553346 0.24 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr15_+_43885252 0.24 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr11_-_110583912 0.24 ENST00000533353.1
ENST00000527598.1
ARHGAP20
Rho GTPase activating protein 20
chr10_+_76586348 0.24 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr3_-_179322436 0.24 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr1_+_169075554 0.23 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_+_1248547 0.23 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr5_-_137911049 0.23 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr3_-_179322416 0.23 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr14_+_23791159 0.22 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr7_-_150777949 0.22 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr7_-_150777920 0.22 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr8_-_70745575 0.22 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr4_-_74088800 0.21 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr15_+_43985084 0.21 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr7_+_129007964 0.21 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr1_+_212738676 0.20 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr7_-_27169801 0.20 ENST00000511914.1
HOXA4
homeobox A4
chr12_-_108954933 0.20 ENST00000431469.2
ENST00000546815.1
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr16_-_69368774 0.20 ENST00000562949.1
RP11-343C2.12
Conserved oligomeric Golgi complex subunit 8
chr17_-_79167828 0.20 ENST00000570817.1
AZI1
5-azacytidine induced 1
chr7_-_81399411 0.19 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr9_-_138853156 0.19 ENST00000371756.3
UBAC1
UBA domain containing 1
chr16_-_66952742 0.19 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chrX_+_44732757 0.19 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr7_-_91875358 0.19 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr12_-_46121554 0.19 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr2_-_176046391 0.18 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr1_-_157108130 0.18 ENST00000368192.4
ETV3
ets variant 3
chr1_+_206858328 0.18 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr12_+_120875910 0.18 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr17_-_2614927 0.18 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr14_-_55369525 0.18 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr11_+_3876859 0.17 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr15_-_42783303 0.17 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr19_+_45394477 0.17 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr10_-_51623203 0.17 ENST00000444743.1
ENST00000374065.3
ENST00000374064.3
ENST00000260867.4
TIMM23
translocase of inner mitochondrial membrane 23 homolog (yeast)
chr16_+_4674787 0.17 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr4_-_71705082 0.17 ENST00000439371.1
ENST00000499044.2
GRSF1
G-rich RNA sequence binding factor 1
chr16_-_70729496 0.17 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr22_-_43036607 0.17 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr14_+_27342334 0.16 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1
RP11-384J4.1
chr16_+_30675654 0.16 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr3_-_49459878 0.16 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr5_-_176981417 0.16 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B
family with sequence similarity 193, member B
chr3_-_46000064 0.15 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr15_+_43985725 0.15 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr7_+_73245193 0.15 ENST00000340958.2
CLDN4
claudin 4
chr10_+_14880287 0.15 ENST00000437161.2
HSPA14
heat shock 70kDa protein 14
chr3_+_51741072 0.15 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr3_+_128968437 0.15 ENST00000314797.6
COPG1
coatomer protein complex, subunit gamma 1
chr4_+_146560245 0.15 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr8_+_145149930 0.14 ENST00000318911.4
CYC1
cytochrome c-1
chr3_+_179322481 0.14 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr20_+_30865429 0.14 ENST00000375712.3
KIF3B
kinesin family member 3B
chr1_-_241683001 0.14 ENST00000366560.3
FH
fumarate hydratase
chr6_-_31628512 0.14 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr3_-_49459865 0.13 ENST00000427987.1
AMT
aminomethyltransferase
chr12_+_7169887 0.13 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr1_-_154164534 0.13 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr1_-_1711508 0.13 ENST00000378625.1
NADK
NAD kinase
chr9_-_115983641 0.13 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr22_+_50354104 0.13 ENST00000360612.4
PIM3
pim-3 oncogene
chr2_+_119981384 0.13 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP3
STEAP family member 3, metalloreductase
chr10_+_22605374 0.13 ENST00000448361.1
COMMD3
COMM domain containing 3
chr12_+_120875887 0.12 ENST00000229379.2
COX6A1
cytochrome c oxidase subunit VIa polypeptide 1
chr17_+_45973516 0.12 ENST00000376741.4
SP2
Sp2 transcription factor
chr2_+_220299547 0.12 ENST00000312358.7
SPEG
SPEG complex locus
chr17_+_79670386 0.12 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr3_+_138340049 0.12 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr2_+_219745020 0.12 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr4_-_40517984 0.12 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr3_-_52860850 0.12 ENST00000441637.2
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr20_-_33999766 0.12 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
UQCC1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr22_+_30821732 0.11 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr4_+_20255123 0.11 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr3_-_10028366 0.11 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chr8_+_134125727 0.11 ENST00000521107.1
TG
thyroglobulin
chr10_+_5932174 0.11 ENST00000362091.4
FBXO18
F-box protein, helicase, 18
chr14_+_22320634 0.11 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr2_+_198365122 0.11 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr17_+_79679299 0.11 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr10_-_50122277 0.11 ENST00000374160.3
LRRC18
leucine rich repeat containing 18
chr2_-_25194476 0.10 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr4_-_140527848 0.10 ENST00000608795.1
ENST00000608958.1
SETD7
SET domain containing (lysine methyltransferase) 7
chr3_+_113465866 0.10 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr2_+_198365095 0.10 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chrX_+_69454505 0.10 ENST00000374521.3
AWAT1
acyl-CoA wax alcohol acyltransferase 1
chr6_-_76072719 0.10 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr10_+_22605304 0.10 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr2_+_109237717 0.10 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr10_+_14880157 0.09 ENST00000378372.3
HSPA14
heat shock 70kDa protein 14
chr3_-_49377499 0.09 ENST00000265560.4
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr3_+_138340067 0.09 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chrX_-_63005405 0.09 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr7_-_91875109 0.09 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1
KRIT1, ankyrin repeat containing
chr12_-_114843889 0.08 ENST00000405440.2
TBX5
T-box 5
chr20_+_44421137 0.08 ENST00000415790.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr12_-_56753858 0.08 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr10_-_51371321 0.08 ENST00000602930.1
AGAP8
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
chr16_-_68269971 0.08 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr17_-_56358287 0.08 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr14_-_92572894 0.08 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr8_+_145582633 0.08 ENST00000540505.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr7_+_148287657 0.08 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr5_+_218356 0.08 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr16_-_30537839 0.08 ENST00000380412.5
ZNF768
zinc finger protein 768
chr4_-_140216948 0.08 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr8_-_100905850 0.08 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C
cytochrome c oxidase subunit VIc
chr10_-_120938303 0.07 ENST00000356951.3
ENST00000298510.2
PRDX3
peroxiredoxin 3
chr3_+_129247479 0.07 ENST00000296271.3
RHO
rhodopsin
chr19_+_54606145 0.07 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr7_-_105029812 0.07 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr10_+_51371390 0.07 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
TIMM23B
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr16_+_11038345 0.07 ENST00000409790.1
CLEC16A
C-type lectin domain family 16, member A
chr1_-_205719295 0.07 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr8_-_100905925 0.07 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr6_-_87804815 0.07 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr5_-_131347583 0.07 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr1_+_45140360 0.07 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr1_+_201924619 0.07 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr12_-_57039739 0.06 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr9_+_33629119 0.06 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr11_+_34938119 0.06 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X
chr18_-_19284724 0.06 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr17_+_79679369 0.06 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr12_+_51818586 0.06 ENST00000394856.1
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr22_-_30783075 0.06 ENST00000215798.6
RNF215
ring finger protein 215
chr6_-_107077347 0.06 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr6_+_136172820 0.06 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr18_-_43678241 0.06 ENST00000593152.2
ENST00000589252.1
ENST00000590665.1
ENST00000398752.6
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr3_-_167452298 0.06 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr22_-_38506619 0.05 ENST00000332536.5
ENST00000381669.3
BAIAP2L2
BAI1-associated protein 2-like 2
chr19_+_45251804 0.05 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr19_+_4153598 0.05 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.4 1.2 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 1.0 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 0.5 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.4 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.3 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 1.0 GO:0061525 hindgut development(GO:0061525)
0.1 0.8 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.4 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0021966 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance(GO:0021966) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 3.5 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 1.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.9 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.4 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.3 2.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.8 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.9 GO:0036038 MKS complex(GO:0036038)
0.0 1.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.2 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.8 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.7 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0015266 protein channel activity(GO:0015266)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237) Roundabout binding(GO:0048495)
0.0 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 3.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs