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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for OVOL1

Z-value: 0.28

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Transcription factors associated with OVOL1

Gene Symbol Gene ID Gene Info
OVOL1
ENSG00000172818.5 ovo like transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OVOL1hg19_v2_chr11_+_65554493_65554546-0.144.7e-01Click!

Activity profile of OVOL1 motif

Sorted Z-values of OVOL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_16509101 0.86 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr5_+_140261703 0.61 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr3_-_165555200 0.55 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr1_-_19186176 0.49 ENST00000375371.3
TAS1R2
taste receptor, type 1, member 2
chrX_-_117107680 0.45 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chrX_-_117107542 0.44 ENST00000371878.1
KLHL13
kelch-like family member 13
chr11_-_75017734 0.30 ENST00000532525.1
ARRB1
arrestin, beta 1
chr19_+_6772710 0.24 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1
vav 1 guanine nucleotide exchange factor
chr4_+_76481258 0.19 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr14_+_29241910 0.17 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr10_-_73848086 0.17 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_73848531 0.17 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_174846570 0.15 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr11_-_130786333 0.15 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr7_+_119913688 0.14 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr10_-_73848764 0.13 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr15_-_64386120 0.12 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr4_-_68620053 0.11 ENST00000420975.2
ENST00000226413.4
GNRHR
gonadotropin-releasing hormone receptor
chr17_-_7145475 0.10 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr15_-_64385981 0.09 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr13_-_50367057 0.08 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr6_-_84419101 0.07 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
SNAP91
synaptosomal-associated protein, 91kDa
chr16_-_67260691 0.06 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr11_+_71710973 0.05 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr15_+_75335604 0.05 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr20_+_54823788 0.02 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr4_+_39408470 0.00 ENST00000257408.4
KLB
klotho beta
chr2_-_183387430 0.00 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent

Network of associatons between targets according to the STRING database.

First level regulatory network of OVOL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway