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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for POU5F1_POU2F3

Z-value: 0.98

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.11 POU class 5 homeobox 1
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F3hg19_v2_chr11_+_120107344_120107351-0.596.1e-04Click!
POU5F1hg19_v2_chr6_-_31138439_311384750.402.7e-02Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153044083 6.33 ENST00000341611.2
small proline-rich protein 2B
chr1_-_153029980 6.08 ENST00000392653.2
small proline-rich protein 2A
chr1_-_153066998 5.25 ENST00000368750.3
small proline-rich protein 2E
chr1_-_153013588 4.66 ENST00000360379.3
small proline-rich protein 2D
chr2_-_113594279 4.35 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr9_+_132099158 3.75 ENST00000444125.1
RP11-65J3.1
chr19_-_50143452 3.43 ENST00000246792.3
related RAS viral (r-ras) oncogene homolog
chr1_+_17575584 2.71 ENST00000375460.3
peptidyl arginine deiminase, type III
chr20_+_361890 2.62 ENST00000449710.1
ENST00000422053.2
tribbles pseudokinase 3
chr17_+_62461569 2.61 ENST00000603557.1
ENST00000605096.1
mast cell immunoglobulin-like receptor 1
chr8_+_7752151 2.55 ENST00000302247.2
defensin, beta 4A
chr20_+_361261 2.38 ENST00000217233.3
tribbles pseudokinase 3
chr6_+_26183958 2.23 ENST00000356530.3
histone cluster 1, H2be
chr12_+_107712173 2.09 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr1_-_153085984 2.05 ENST00000468739.1
small proline-rich protein 2F
chr6_-_35656685 2.05 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr3_+_130650738 1.93 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chr4_-_139163491 1.91 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr6_-_35656712 1.91 ENST00000357266.4
ENST00000542713.1
FK506 binding protein 5
chr6_+_26251835 1.88 ENST00000356350.2
histone cluster 1, H2bh
chr6_-_26124138 1.85 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr19_+_39903185 1.83 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr6_-_27114577 1.83 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr1_+_228645796 1.83 ENST00000369160.2
histone cluster 3, H2bb
chr9_+_33750667 1.82 ENST00000457896.1
ENST00000342836.4
ENST00000429677.3
protease, serine, 3
chr9_+_33750515 1.80 ENST00000361005.5
protease, serine, 3
chr15_+_45406519 1.77 ENST00000323030.5
dual oxidase maturation factor 2
chr2_+_174219548 1.71 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
cell division cycle associated 7
chr2_+_89890533 1.65 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr6_+_37137939 1.61 ENST00000373509.5
pim-1 oncogene
chr8_+_39759794 1.57 ENST00000518804.1
ENST00000519154.1
ENST00000522495.1
ENST00000522840.1
indoleamine 2,3-dioxygenase 1
chr8_+_85618155 1.54 ENST00000523850.1
ENST00000521376.1
RALY RNA binding protein-like
chr12_-_10978957 1.54 ENST00000240619.2
taste receptor, type 2, member 10
chr1_-_153113927 1.53 ENST00000368752.4
small proline-rich protein 2B
chr12_-_123201337 1.52 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr12_-_123187890 1.52 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr4_-_39034542 1.51 ENST00000344606.6
transmembrane protein 156
chr5_-_39270725 1.51 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr2_+_89998789 1.51 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr8_+_25316707 1.47 ENST00000380665.3
cell division cycle associated 2
chr12_-_57634475 1.46 ENST00000393825.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr16_+_32077386 1.46 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr1_+_152975488 1.45 ENST00000542696.1
small proline-rich protein 3
chr2_+_210444748 1.45 ENST00000392194.1
microtubule-associated protein 2
chr8_+_25316489 1.44 ENST00000330560.3
cell division cycle associated 2
chr16_-_79634595 1.40 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr14_-_107095662 1.34 ENST00000390630.2
immunoglobulin heavy variable 4-61
chr5_-_39203093 1.33 ENST00000515010.1
FYN binding protein
chr2_+_90077680 1.32 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr17_-_45908875 1.32 ENST00000351111.2
ENST00000414011.1
mitochondrial ribosomal protein L10
chr14_-_57272366 1.32 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
orthodenticle homeobox 2
chr1_-_153348067 1.32 ENST00000368737.3
S100 calcium binding protein A12
chr2_-_89521942 1.31 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr22_+_44319619 1.31 ENST00000216180.3
patatin-like phospholipase domain containing 3
chr19_+_52873166 1.29 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr7_+_18535786 1.25 ENST00000406072.1
histone deacetylase 9
chr14_-_107083690 1.25 ENST00000455737.1
ENST00000390629.2
immunoglobulin heavy variable 4-59
chr22_+_44319648 1.25 ENST00000423180.2
patatin-like phospholipase domain containing 3
chr6_-_11779403 1.24 ENST00000414691.3
androgen-dependent TFPI-regulating protein
chr22_+_21987005 1.24 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
coiled-coil domain containing 116
chr12_-_67072714 1.22 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
glutamate receptor interacting protein 1
chr20_-_54967187 1.21 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr12_+_113344755 1.19 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_89442621 1.19 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr2_+_89975669 1.19 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr2_-_89545079 1.18 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr11_-_64085533 1.15 ENST00000544844.1
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr11_-_64084959 1.15 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr2_-_208030647 1.14 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr2_+_90060377 1.12 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr15_+_67458357 1.12 ENST00000537194.2
SMAD family member 3
chr3_-_48594248 1.11 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr2_+_105050794 1.11 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr7_-_41742697 1.09 ENST00000242208.4
inhibin, beta A
chr7_-_93520259 1.09 ENST00000222543.5
tissue factor pathway inhibitor 2
chr6_+_26124373 1.08 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr14_-_106830057 1.08 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr11_+_111126707 1.07 ENST00000280325.4
chromosome 11 open reading frame 53
chr4_+_5526883 1.07 ENST00000195455.2
chromosome 4 open reading frame 6
chr10_-_29811456 1.07 ENST00000535393.1
supervillin
chr15_-_80263506 1.05 ENST00000335661.6
BCL2-related protein A1
chr2_-_188419078 1.03 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_-_190044480 1.03 ENST00000374866.3
collagen, type V, alpha 2
chr4_-_159094194 1.02 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr7_+_143174966 1.02 ENST00000408916.1
taste receptor, type 2, member 41
chr1_-_197115818 1.01 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr20_+_306177 1.01 ENST00000544632.1
SRY (sex determining region Y)-box 12
chr17_-_7307358 1.00 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr4_-_99578776 1.00 ENST00000515287.1
tetraspanin 5
chr7_+_80275953 0.99 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr10_-_3827417 0.98 ENST00000497571.1
ENST00000542957.1
Kruppel-like factor 6
chr11_-_568369 0.97 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210 host gene (non-protein coding)
chr3_-_111314230 0.97 ENST00000317012.4
zinc finger, BED-type containing 2
chr2_+_90108504 0.95 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_234600253 0.94 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_+_34204642 0.94 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr11_+_125495862 0.93 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
checkpoint kinase 1
chr6_-_39290316 0.93 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
potassium channel, subfamily K, member 16
chr21_+_10862622 0.93 ENST00000302092.5
ENST00000559480.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_-_188419200 0.93 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_136343820 0.93 ENST00000410054.1
R3H domain containing 1
chr1_-_68962805 0.92 ENST00000370966.5
DEP domain containing 1
chr4_-_99578789 0.92 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr18_+_47088401 0.92 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr19_-_1132207 0.91 ENST00000438103.2
strawberry notch homolog 2 (Drosophila)
chr11_-_2906979 0.90 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr7_-_93520191 0.90 ENST00000545378.1
tissue factor pathway inhibitor 2
chr1_-_68962782 0.90 ENST00000456315.2
DEP domain containing 1
chr22_+_23089870 0.89 ENST00000390311.2
immunoglobulin lambda variable 3-16
chr3_+_50192537 0.89 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_-_125577940 0.89 ENST00000519168.1
ENST00000395508.2
metastasis suppressor 1
chr17_+_38171681 0.88 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
colony stimulating factor 3 (granulocyte)
chr6_-_108145499 0.88 ENST00000369020.3
ENST00000369022.2
sex comb on midleg-like 4 (Drosophila)
chr1_+_6052700 0.88 ENST00000378092.1
ENST00000445501.1
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr20_-_60982330 0.88 ENST00000279101.5
Cdk5 and Abl enzyme substrate 2
chr15_-_56209306 0.87 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr1_-_149783914 0.87 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
histone cluster 2, H2bf
chr3_+_50192499 0.86 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr20_+_34556488 0.86 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
cyclic nucleotide binding domain containing 2
chr22_-_28197486 0.86 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr14_-_106573756 0.86 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr14_+_32798547 0.85 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr14_+_32798462 0.85 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr3_+_130569592 0.84 ENST00000533801.2
ATPase, Ca++ transporting, type 2C, member 1
chr11_-_31832581 0.84 ENST00000379111.2
paired box 6
chr22_+_38093005 0.84 ENST00000406386.3
TRIO and F-actin binding protein
chr6_+_27861190 0.83 ENST00000303806.4
histone cluster 1, H2bo
chr17_+_38171614 0.83 ENST00000583218.1
ENST00000394149.3
colony stimulating factor 3 (granulocyte)
chr15_-_72612470 0.82 ENST00000287202.5
CUGBP, Elav-like family member 6
chr6_-_26043885 0.82 ENST00000357905.2
histone cluster 1, H2bb
chr14_-_106610852 0.82 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr2_+_210444142 0.82 ENST00000360351.4
ENST00000361559.4
microtubule-associated protein 2
chr19_+_926000 0.81 ENST00000263620.3
AT rich interactive domain 3A (BRIGHT-like)
chr5_+_96212185 0.81 ENST00000379904.4
endoplasmic reticulum aminopeptidase 2
chr7_-_3083573 0.80 ENST00000396946.4
caspase recruitment domain family, member 11
chr5_+_96211643 0.80 ENST00000437043.3
ENST00000510373.1
endoplasmic reticulum aminopeptidase 2
chr14_-_106552755 0.80 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr14_+_79745682 0.79 ENST00000557594.1
neurexin 3
chr14_-_106494587 0.77 ENST00000390597.2
immunoglobulin heavy variable 2-5
chr15_-_45406385 0.77 ENST00000389039.6
dual oxidase 2
chr3_-_33686925 0.77 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chrX_-_106960285 0.76 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chrX_-_73072534 0.76 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr3_+_63428752 0.76 ENST00000295894.5
synaptoporin
chr22_-_27456361 0.76 ENST00000453934.1
CTA-992D9.6
chr14_-_106478603 0.76 ENST00000390596.2
immunoglobulin heavy variable 4-4
chr1_-_40157345 0.76 ENST00000372844.3
hippocalcin like 4
chr15_+_63334831 0.75 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
tropomyosin 1 (alpha)
chr3_+_63428982 0.75 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
synaptoporin
chr6_-_131291572 0.75 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr4_+_5527117 0.75 ENST00000505296.1
chromosome 4 open reading frame 6
chr12_+_113344811 0.75 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr3_+_57882024 0.74 ENST00000494088.1
sarcolemma associated protein
chr13_-_30881134 0.74 ENST00000380617.3
ENST00000441394.1
katanin p60 subunit A-like 1
chr2_+_201173667 0.74 ENST00000409755.3
spermatogenesis associated, serine-rich 2-like
chr14_-_106791536 0.74 ENST00000390613.2
immunoglobulin heavy variable 3-30
chr11_-_31832862 0.73 ENST00000379115.4
paired box 6
chr22_-_24096562 0.73 ENST00000398465.3
pre-B lymphocyte 3
chr7_-_50860565 0.71 ENST00000403097.1
growth factor receptor-bound protein 10
chr18_+_657578 0.71 ENST00000323274.10
thymidylate synthetase
chr11_-_78140882 0.70 ENST00000513207.2
RP11-452H21.4
chr3_-_113918254 0.70 ENST00000460779.1
dopamine receptor D3
chr20_+_306221 0.70 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr11_-_31832785 0.70 ENST00000241001.8
paired box 6
chr7_-_128049955 0.70 ENST00000419067.2
ENST00000378717.4
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr12_-_50419177 0.70 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
Rac GTPase activating protein 1
chr4_-_47983519 0.70 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chrX_-_65259900 0.69 ENST00000412866.2
V-set and immunoglobulin domain containing 4
chr9_-_36276966 0.69 ENST00000543356.2
ENST00000396594.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr6_+_27782788 0.69 ENST00000359465.4
histone cluster 1, H2bm
chr1_+_87012753 0.69 ENST00000370563.3
chloride channel accessory 4
chr16_+_23690138 0.69 ENST00000300093.4
polo-like kinase 1
chr2_-_89327228 0.69 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr14_-_107049312 0.68 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr13_-_36050819 0.68 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr2_-_89247338 0.68 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr6_-_110501200 0.68 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WAS protein family, member 1
chr7_+_141463897 0.68 ENST00000247879.2
taste receptor, type 2, member 3
chr21_+_30502806 0.68 ENST00000399928.1
ENST00000399926.1
MAP3K7 C-terminal like
chr2_+_90211643 0.68 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr22_+_23063100 0.67 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr16_-_79633799 0.67 ENST00000569649.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr4_-_100065419 0.67 ENST00000504125.1
ENST00000505590.1
alcohol dehydrogenase 4 (class II), pi polypeptide
chr2_+_196521458 0.67 ENST00000409086.3
solute carrier family 39 (zinc transporter), member 10
chr3_-_87040233 0.67 ENST00000398399.2
vestigial like 3 (Drosophila)
chr1_+_116654376 0.66 ENST00000369500.3
mab-21-like 3 (C. elegans)
chr1_-_26185844 0.66 ENST00000538789.1
ENST00000374298.3
aurora kinase A and ninein interacting protein
chr22_-_24096630 0.66 ENST00000248948.3
pre-B lymphocyte 3
chr22_-_20367797 0.66 ENST00000424787.2
gamma-glutamyltransferase light chain 3
chr4_+_70796784 0.65 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr4_+_41258786 0.65 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr17_+_43213004 0.65 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
acyl-CoA binding domain containing 4
chr5_-_39425290 0.65 ENST00000545653.1
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chrX_-_65259914 0.65 ENST00000374737.4
ENST00000455586.2
V-set and immunoglobulin domain containing 4
chrX_+_150148976 0.65 ENST00000419110.1
high mobility group box 3
chr2_+_113816215 0.65 ENST00000346807.3
interleukin 36 receptor antagonist
chr11_+_69455855 0.65 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr12_-_122240792 0.65 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
ras homolog family member F (in filopodia)
chr6_-_32784687 0.64 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr19_+_17858509 0.64 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCH domain only 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.5 2.7 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 3.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.5 2.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.5 1.8 GO:0036269 swimming behavior(GO:0036269)
0.5 2.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.4 1.2 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.4 1.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 28.3 GO:0018149 peptide cross-linking(GO:0018149)
0.4 1.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.4 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3 1.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.3 1.6 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 1.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 0.9 GO:1902534 single-organism membrane invagination(GO:1902534)
0.3 2.3 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.3 1.4 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.3 1.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 1.4 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.3 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 0.5 GO:0010165 response to X-ray(GO:0010165)
0.2 2.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.9 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 1.8 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.2 1.8 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.2 2.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 5.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 0.7 GO:0007412 axon target recognition(GO:0007412)
0.2 1.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.2 1.1 GO:0071105 response to interleukin-11(GO:0071105)
0.2 0.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 0.2 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843)
0.2 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 0.7 GO:0019860 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.2 1.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 0.7 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 0.7 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 2.6 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.2 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 0.8 GO:0030047 actin modification(GO:0030047)
0.2 1.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 1.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.2 0.9 GO:0030035 microspike assembly(GO:0030035)
0.2 1.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 6.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 1.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 0.1 GO:0005984 maltose metabolic process(GO:0000023) disaccharide metabolic process(GO:0005984)
0.1 1.6 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.6 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.7 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 3.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.5 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.1 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.5 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.4 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 1.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.6 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 4.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 2.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.3 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.1 0.2 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 3.4 GO:0060325 face morphogenesis(GO:0060325)
0.1 14.0 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.4 GO:0021650 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.1 1.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.4 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.4 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 5.8 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.7 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.1 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.3 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.8 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.6 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 1.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.6 GO:0002544 chronic inflammatory response(GO:0002544)
0.1 0.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.5 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.6 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.1 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 0.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 4.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.3 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 2.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.8 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 3.5 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 1.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.3 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.3 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.1 0.2 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.1 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.2 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 0.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:0090042 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.1 0.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.1 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1 0.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 1.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.7 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.3 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.5 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 1.1 GO:0031033 myosin filament organization(GO:0031033)
0.1 0.2 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 1.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.2 GO:0035549 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.7 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 7.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 6.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.9 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:2000547 myeloid dendritic cell chemotaxis(GO:0002408) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.3 GO:0050966 neuronal action potential propagation(GO:0019227) detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) action potential propagation(GO:0098870)
0.0 0.4 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:1900157 positive regulation of osteoclast proliferation(GO:0090290) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.3 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.7 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.8 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.0 0.3 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.8 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.3 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.4 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 2.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0097254 renal tubular secretion(GO:0097254)
0.0 0.1 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.3 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.3 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0032352 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 2.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720) guanine metabolic process(GO:0046098) response to fungicide(GO:0060992)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.1 GO:1901256 macrophage colony-stimulating factor production(GO:0036301) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of coagulation(GO:0050818) regulation of hemostasis(GO:1900046)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0034091 regulation of maintenance of sister chromatid cohesion(GO:0034091) positive regulation of maintenance of sister chromatid cohesion(GO:0034093) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.7 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0010889 regulation of sequestering of triglyceride(GO:0010889)
0.0 0.9 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:1903121 negative regulation of ribosome biogenesis(GO:0090071) postsynaptic density assembly(GO:0097107) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 2.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.3 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.5 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.2 GO:0003360 brainstem development(GO:0003360)
0.0 0.0 GO:0071338 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.2 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.9 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.2 GO:0007625 grooming behavior(GO:0007625)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 2.9 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.3 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 1.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0030097 hemopoiesis(GO:0030097) hematopoietic or lymphoid organ development(GO:0048534)
0.0 0.1 GO:0043654 complement activation, lectin pathway(GO:0001867) recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.0 GO:0060459 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.4 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.4 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.3 GO:0016358 dendrite development(GO:0016358)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.6 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0006953 acute-phase response(GO:0006953)
0.0 0.0 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 1.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0043066 negative regulation of apoptotic process(GO:0043066)
0.0 0.3 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.5 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.4 GO:0006935 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 1.9 GO:0008064 regulation of actin polymerization or depolymerization(GO:0008064)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 1.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.0 0.3 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0035904 aorta development(GO:0035904)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0021543 pallium development(GO:0021543)
0.0 0.3 GO:0042220 response to cocaine(GO:0042220)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.0 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.7 GO:0021549 cerebellum development(GO:0021549)
0.0 0.0 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 26.7 GO:0001533 cornified envelope(GO:0001533)
0.4 1.2 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.4 1.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.0 GO:0035841 new growing cell tip(GO:0035841)
0.3 1.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 0.9 GO:1990031 pinceau fiber(GO:1990031)
0.3 1.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 2.1 GO:0036449 microtubule minus-end(GO:0036449)
0.2 0.9 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 1.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 1.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 1.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.5 GO:1990032 parallel fiber(GO:1990032)
0.2 2.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.7 GO:0097149 centralspindlin complex(GO:0097149)
0.1 8.9 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:0044308 axonal spine(GO:0044308)
0.1 0.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.3 GO:0036452 ESCRT I complex(GO:0000813) ESCRT complex(GO:0036452)
0.1 1.3 GO:0032059 bleb(GO:0032059)
0.1 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.1 GO:1990923 PET complex(GO:1990923)
0.1 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 1.0 GO:0032982 myosin filament(GO:0032982)
0.0 2.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 2.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 2.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0043204 perikaryon(GO:0043204)
0.0 4.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0043005 neuron projection(GO:0043005)
0.0 3.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 1.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 2.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0000791 euchromatin(GO:0000791)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 16.0 GO:0005615 extracellular space(GO:0005615)
0.0 1.2 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.1 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.3 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 2.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 1.6 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.5 3.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.4 1.9 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.4 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 5.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 1.6 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 0.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 6.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.3 5.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 0.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 2.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 5.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 0.6 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2 1.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 0.7 GO:0005503 all-trans retinal binding(GO:0005503)
0.2 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 2.6 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.7 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 3.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.6 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 3.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 1.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 1.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.5 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 17.1 GO:0003823 antigen binding(GO:0003823)
0.1 3.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 1.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.1 GO:0019862 IgA binding(GO:0019862)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.7 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.3 GO:0051400 BH domain binding(GO:0051400)
0.1 0.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.9 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 3.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.5 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 1.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0043295 glutathione binding(GO:0043295)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 2.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 22.9 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.0 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 2.3 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.2 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 3.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0034191 GBD domain binding(GO:0032427) apolipoprotein A-I receptor binding(GO:0034191) GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.3 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 3.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.5 PID IGF1 PATHWAY IGF1 pathway
0.0 1.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 2.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 5.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 4.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 10.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 3.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 4.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 1.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 3.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.0 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 3.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 3.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 1.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 4.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport