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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for RARB
Z-value: 0.38
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Transcription factors associated with RARB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RARB | hg19_v2_chr3_+_25469724_25469773 | -0.53 | 2.7e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_132286754 Show fit | 0.80 |
ENST00000434330.1
|
coiled-coil domain containing 74A |
|
| chr1_-_19186176 Show fit | 0.63 |
ENST00000375371.3
|
taste receptor, type 1, member 2 |
|
| chr2_+_132287237 Show fit | 0.56 |
ENST00000467992.2
|
coiled-coil domain containing 74A |
|
| chr12_-_10151773 Show fit | 0.55 |
ENST00000298527.6
ENST00000348658.4 |
C-type lectin domain family 1, member B |
|
| chr19_+_5914213 Show fit | 0.54 |
ENST00000222125.5
ENST00000452990.2 ENST00000588865.1 |
calcyphosine |
|
| chr5_-_35195338 Show fit | 0.52 |
ENST00000509839.1
|
prolactin receptor |
|
| chr6_-_150212029 Show fit | 0.44 |
ENST00000529948.1
ENST00000357183.4 ENST00000367363.3 |
retinoic acid early transcript 1E |
|
| chr5_+_53751445 Show fit | 0.41 |
ENST00000302005.1
|
heat shock 27kDa protein 3 |
|
| chr9_+_131217459 Show fit | 0.39 |
ENST00000497812.2
ENST00000393533.2 |
outer dense fiber of sperm tails 2 |
|
| chr13_+_73302047 Show fit | 0.37 |
ENST00000377814.2
ENST00000377815.3 ENST00000390667.5 |
bora, aurora kinase A activator |
Network of associatons between targets according to the STRING database.
First level regulatory network of RARB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.1 | 0.6 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.1 | 0.6 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.1 | 0.5 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.1 | 0.5 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.0 | 0.5 | GO:0030220 | platelet formation(GO:0030220) |
| 0.0 | 0.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.3 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 0.3 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.1 | 0.2 | GO:0070510 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.3 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.1 | 0.2 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 0.0 | 0.2 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.0 | 0.1 | GO:0005608 | laminin-3 complex(GO:0005608) |
| 0.0 | 0.1 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
| 0.0 | 0.1 | GO:0098536 | deuterosome(GO:0098536) |
| 0.0 | 0.1 | GO:0000125 | PCAF complex(GO:0000125) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.1 | 0.8 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.0 | 0.6 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.0 | 0.6 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.2 | 0.5 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 0.1 | 0.5 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 0.3 | GO:0035473 | lipase binding(GO:0035473) |
| 0.0 | 0.3 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 0.3 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.3 | GO:0042609 | CD4 receptor binding(GO:0042609) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | PID PLK1 PATHWAY | PLK1 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.6 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.6 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.5 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.4 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.4 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.3 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 0.3 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |