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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TP63

Z-value: 1.34

Motif logo

Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
ENSG00000073282.8 tumor protein p63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189349162_1893493050.761.0e-06Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51504411 14.45 ENST00000593490.1
kallikrein-related peptidase 8
chr19_-_51471381 8.57 ENST00000594641.1
kallikrein-related peptidase 6
chr19_-_19051103 5.60 ENST00000542541.2
ENST00000433218.2
homer homolog 3 (Drosophila)
chr2_-_216003127 4.94 ENST00000412081.1
ENST00000272895.7
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_+_151030234 4.78 ENST00000368921.3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr12_-_52845910 4.54 ENST00000252252.3
keratin 6B
chr20_-_43280325 4.51 ENST00000537820.1
adenosine deaminase
chr4_-_10023095 4.43 ENST00000264784.3
solute carrier family 2 (facilitated glucose transporter), member 9
chr12_+_119616447 4.17 ENST00000281938.2
heat shock 22kDa protein 8
chr2_-_31361543 4.00 ENST00000349752.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr3_-_50340996 3.96 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
hyaluronoglucosaminidase 1
chr1_+_17575584 3.88 ENST00000375460.3
peptidyl arginine deiminase, type III
chr1_-_26197744 3.79 ENST00000374296.3
progestin and adipoQ receptor family member VII
chr20_-_43280361 3.63 ENST00000372874.4
adenosine deaminase
chr10_+_102106829 3.61 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chrX_-_153602991 3.50 ENST00000369850.3
ENST00000422373.1
filamin A, alpha
chr1_+_86889769 3.43 ENST00000370565.4
chloride channel accessory 2
chr18_+_34124507 3.42 ENST00000591635.1
formin homology 2 domain containing 3
chr1_-_47655686 3.33 ENST00000294338.2
PDZK1 interacting protein 1
chr1_-_228603694 3.27 ENST00000366697.2
tripartite motif containing 17
chr19_+_18496957 3.17 ENST00000252809.3
growth differentiation factor 15
chr22_+_31489344 3.05 ENST00000404574.1
smoothelin
chr7_+_80267973 2.95 ENST00000394788.3
ENST00000447544.2
CD36 molecule (thrombospondin receptor)
chr20_-_52790512 2.89 ENST00000216862.3
cytochrome P450, family 24, subfamily A, polypeptide 1
chr10_+_99344104 2.73 ENST00000555577.1
ENST00000370649.3
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr18_+_61143994 2.49 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr20_-_6103666 2.47 ENST00000536936.1
fermitin family member 1
chr19_-_11688447 2.43 ENST00000590420.1
acid phosphatase 5, tartrate resistant
chr22_+_38302285 2.38 ENST00000215957.6
MICAL-like 1
chr12_-_125348329 2.35 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
scavenger receptor class B, member 1
chr1_+_38158090 2.34 ENST00000373055.1
ENST00000327331.2
cell division cycle associated 8
chr6_+_106546808 2.27 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr10_-_90751038 2.24 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr17_+_26662597 2.23 ENST00000544907.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr6_+_121756809 2.20 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chrX_+_2670066 2.19 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
Xg blood group
chr12_+_120105558 2.16 ENST00000229328.5
ENST00000541640.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr8_-_23021533 2.12 ENST00000312584.3
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr19_-_11688500 2.04 ENST00000433365.2
acid phosphatase 5, tartrate resistant
chr8_+_22960426 2.00 ENST00000540813.1
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr19_+_535835 1.97 ENST00000607527.1
ENST00000606065.1
cell division cycle 34
chr7_+_102389434 1.96 ENST00000409231.3
ENST00000418198.1
family with sequence similarity 185, member A
chr17_+_26662730 1.96 ENST00000226225.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chrX_+_150148976 1.96 ENST00000419110.1
high mobility group box 3
chr12_-_125348448 1.95 ENST00000339570.5
scavenger receptor class B, member 1
chr8_-_22926526 1.94 ENST00000347739.3
ENST00000542226.1
tumor necrosis factor receptor superfamily, member 10b
chr1_+_24645865 1.90 ENST00000342072.4
grainyhead-like 3 (Drosophila)
chr1_+_24645807 1.87 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr1_+_24646002 1.85 ENST00000356046.2
grainyhead-like 3 (Drosophila)
chr14_+_51955831 1.80 ENST00000356218.4
FERM domain containing 6
chr9_+_35906176 1.78 ENST00000354323.2
histidine rich carboxyl terminus 1
chr6_-_30712313 1.78 ENST00000376377.2
ENST00000259874.5
immediate early response 3
chr11_-_111782484 1.77 ENST00000533971.1
crystallin, alpha B
chr15_-_89456630 1.74 ENST00000268150.8
milk fat globule-EGF factor 8 protein
chr11_+_77899920 1.71 ENST00000528910.1
ENST00000529308.1
ubiquitin specific peptidase 35
chr10_-_105212059 1.69 ENST00000260743.5
calcium homeostasis modulator 2
chr2_-_165698662 1.69 ENST00000194871.6
ENST00000445474.2
cordon-bleu WH2 repeat protein-like 1
chrX_+_152086373 1.63 ENST00000318529.8
zinc finger protein 185 (LIM domain)
chr11_+_65686728 1.61 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_+_48824711 1.61 ENST00000599704.1
epithelial membrane protein 3
chr2_+_234600253 1.58 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr14_-_94595993 1.58 ENST00000238609.3
interferon, alpha-inducible protein 27-like 2
chr17_+_75450075 1.55 ENST00000592951.1
septin 9
chr15_-_89456593 1.50 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
milk fat globule-EGF factor 8 protein
chr17_+_80332153 1.49 ENST00000313135.2
urotensin 2 receptor
chr22_+_24999114 1.48 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
gamma-glutamyltransferase 1
chr8_-_49833978 1.47 ENST00000020945.1
snail family zinc finger 2
chr12_-_96184533 1.47 ENST00000343702.4
ENST00000344911.4
netrin 4
chr10_-_105212141 1.43 ENST00000369788.3
calcium homeostasis modulator 2
chr1_-_19229248 1.43 ENST00000375341.3
aldehyde dehydrogenase 4 family, member A1
chr4_-_21546272 1.42 ENST00000509207.1
Kv channel interacting protein 4
chr1_-_93426998 1.42 ENST00000370310.4
family with sequence similarity 69, member A
chr1_-_19229014 1.39 ENST00000538839.1
ENST00000290597.5
aldehyde dehydrogenase 4 family, member A1
chr1_-_153588334 1.29 ENST00000476873.1
S100 calcium binding protein A14
chr9_+_116298778 1.28 ENST00000462143.1
regulator of G-protein signaling 3
chr3_+_136676851 1.27 ENST00000309741.5
interleukin 20 receptor beta
chr9_+_139553306 1.26 ENST00000371699.1
EGF-like-domain, multiple 7
chr8_-_22926623 1.25 ENST00000276431.4
tumor necrosis factor receptor superfamily, member 10b
chr3_-_45017609 1.25 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
zinc finger, DHHC-type containing 3
chr1_-_209824643 1.23 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr15_-_42448788 1.21 ENST00000382396.4
ENST00000397272.3
phospholipase A2, group IVF
chr3_+_136676707 1.17 ENST00000329582.4
interleukin 20 receptor beta
chr1_-_152552980 1.15 ENST00000368787.3
late cornified envelope 3D
chr16_+_23652773 1.15 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
dynactin 5 (p25)
chr3_+_44379611 1.12 ENST00000383746.3
ENST00000417237.1
T cell activation inhibitor, mitochondrial
chr4_+_3388057 1.11 ENST00000538395.1
regulator of G-protein signaling 12
chr12_-_52887034 1.11 ENST00000330722.6
keratin 6A
chr2_-_165698521 1.10 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
cordon-bleu WH2 repeat protein-like 1
chr2_-_47168850 1.09 ENST00000409207.1
multiple coagulation factor deficiency 2
chr11_+_18287801 1.08 ENST00000532858.1
ENST00000405158.2
serum amyloid A1
chr11_+_18287721 1.07 ENST00000356524.4
serum amyloid A1
chr1_-_94312706 1.07 ENST00000370244.1
breast cancer anti-estrogen resistance 3
chr5_+_153570319 1.06 ENST00000377661.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr16_+_8807419 1.06 ENST00000565016.1
ENST00000567812.1
4-aminobutyrate aminotransferase
chr4_+_2794750 1.02 ENST00000452765.2
ENST00000389838.2
SH3-domain binding protein 2
chr4_+_8321882 1.02 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
chr8_+_22853345 1.01 ENST00000522948.1
Rho-related BTB domain containing 2
chr19_+_49458107 1.00 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr3_-_33700589 1.00 ENST00000461133.3
ENST00000496954.2
cytoplasmic linker associated protein 2
chr6_+_54711533 1.00 ENST00000306858.7
family with sequence similarity 83, member B
chr13_+_42846272 0.98 ENST00000025301.2
A kinase (PRKA) anchor protein 11
chr20_+_30467600 0.97 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chr6_+_134758827 0.96 ENST00000431422.1
long intergenic non-protein coding RNA 1010
chr16_+_1832902 0.96 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
nucleotide binding protein 2
chr15_+_68570062 0.95 ENST00000306917.4
fem-1 homolog b (C. elegans)
chr7_+_23145884 0.94 ENST00000409689.1
ENST00000410047.1
kelch-like family member 7
chr21_+_44313375 0.94 ENST00000354250.2
ENST00000340344.4
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr19_+_35861831 0.92 ENST00000454971.1
G protein-coupled receptor 42 (gene/pseudogene)
chr19_+_35862192 0.92 ENST00000597214.1
G protein-coupled receptor 42 (gene/pseudogene)
chr1_+_154300217 0.90 ENST00000368489.3
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr6_-_44923160 0.89 ENST00000371458.1
suppressor of Ty 3 homolog (S. cerevisiae)
chr19_+_35849362 0.88 ENST00000327809.4
free fatty acid receptor 3
chr11_+_61891445 0.87 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
inner centromere protein antigens 135/155kDa
chr6_-_101329157 0.84 ENST00000369143.2
activating signal cointegrator 1 complex subunit 3
chr15_-_55700216 0.84 ENST00000569205.1
cell cycle progression 1
chr8_-_117778494 0.84 ENST00000276682.4
eukaryotic translation initiation factor 3, subunit H
chr2_+_131369054 0.84 ENST00000409602.1
POTE ankyrin domain family, member J
chr3_-_57113314 0.83 ENST00000338458.4
ENST00000468727.1
Rho guanine nucleotide exchange factor (GEF) 3
chr2_+_47168630 0.83 ENST00000263737.6
tetratricopeptide repeat domain 7A
chr19_+_42364460 0.82 ENST00000593863.1
ribosomal protein S19
chr20_+_57264187 0.82 ENST00000525967.1
ENST00000525817.1
aminopeptidase-like 1
chr16_+_30007524 0.81 ENST00000567254.1
ENST00000567705.1
INO80 complex subunit E
chr16_+_30006997 0.81 ENST00000304516.7
INO80 complex subunit E
chr19_-_46288917 0.81 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
dystrophia myotonica, WD repeat containing
Uncharacterized protein
chr3_+_184080387 0.80 ENST00000455712.1
polymerase (RNA) II (DNA directed) polypeptide H
chr22_+_50628999 0.80 ENST00000395827.1
TraB domain containing
chr5_+_153570285 0.79 ENST00000425427.2
ENST00000297107.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr19_+_35849723 0.79 ENST00000594310.1
free fatty acid receptor 3
chr11_-_111782696 0.77 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr18_+_21033239 0.77 ENST00000581585.1
ENST00000577501.1
RIO kinase 3
chr14_-_37642016 0.76 ENST00000331299.5
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr11_-_8190534 0.75 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3 acetylcholine receptor chaperone
chr10_+_75532028 0.73 ENST00000372841.3
ENST00000394790.1
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr6_-_101329191 0.72 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr11_+_18433840 0.72 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr10_+_90750493 0.72 ENST00000357339.2
ENST00000355279.2
Fas cell surface death receptor
chr19_+_42364313 0.71 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
ribosomal protein S19
chr2_-_130878140 0.70 ENST00000360967.5
ENST00000361163.4
ENST00000357462.5
POTE ankyrin domain family, member F
chr21_-_27462351 0.70 ENST00000448850.1
amyloid beta (A4) precursor protein
chr12_+_69202975 0.70 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2 oncogene, E3 ubiquitin protein ligase
chr17_-_74707037 0.70 ENST00000355797.3
ENST00000375036.2
ENST00000449428.2
matrix-remodelling associated 7
chr7_-_72742085 0.69 ENST00000333149.2
tripartite motif containing 50
chr10_+_11059826 0.69 ENST00000450189.1
CUGBP, Elav-like family member 2
chr12_-_126467906 0.68 ENST00000507313.1
ENST00000545784.1
long intergenic non-protein coding RNA 939
chr15_+_32907691 0.68 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
Rho GTPase activating protein 11A
chr2_-_47168906 0.66 ENST00000444761.2
ENST00000409147.1
multiple coagulation factor deficiency 2
chr8_+_126442563 0.66 ENST00000311922.3
tribbles pseudokinase 1
chr12_+_69202795 0.66 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2 oncogene, E3 ubiquitin protein ligase
chr16_-_68000717 0.63 ENST00000541864.2
solute carrier family 12 (potassium/chloride transporter), member 4
chr17_+_79859985 0.62 ENST00000333383.7
neuropeptide B
chr3_+_45017722 0.60 ENST00000265564.7
exosome component 7
chr16_-_47493041 0.59 ENST00000565940.2
integrin alpha FG-GAP repeat containing 1
chr19_+_19779686 0.59 ENST00000415784.2
zinc finger protein 101
chr2_+_108994466 0.59 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr2_-_112614424 0.58 ENST00000427997.1
anaphase promoting complex subunit 1
chr5_+_170814803 0.58 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr16_+_30006615 0.58 ENST00000563197.1
INO80 complex subunit E
chr20_+_35234137 0.58 ENST00000344795.3
ENST00000373852.5
chromosome 20 open reading frame 24
chr17_-_14140166 0.57 ENST00000420162.2
ENST00000431716.2
CMT1A duplicated region transcript 15
chr7_+_23145366 0.57 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
kelch-like family member 7
chr14_+_24779376 0.57 ENST00000530080.1
leukotriene B4 receptor 2
chr22_-_38577782 0.56 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
phospholipase A2, group VI (cytosolic, calcium-independent)
chr16_-_34740829 0.56 ENST00000562591.1
RP11-80F22.15
chr7_-_142207004 0.56 ENST00000426318.2
T cell receptor beta variable 10-2
chr20_+_35234223 0.56 ENST00000342422.3
chromosome 20 open reading frame 24
chr3_+_47844399 0.55 ENST00000446256.2
ENST00000445061.1
DEAH (Asp-Glu-Ala-His) box helicase 30
chr10_+_124913793 0.54 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3 mitotic checkpoint protein
chr6_+_31691121 0.53 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
chromosome 6 open reading frame 25
chr9_+_93589734 0.53 ENST00000375746.1
spleen tyrosine kinase
chr4_-_144826682 0.53 ENST00000358615.4
ENST00000437468.2
glycophorin E (MNS blood group)
chr7_+_72742178 0.52 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr1_+_12040238 0.52 ENST00000444836.1
ENST00000235329.5
mitofusin 2
chr17_+_49230897 0.52 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr10_+_103113840 0.51 ENST00000393441.4
ENST00000408038.2
beta-transducin repeat containing E3 ubiquitin protein ligase
chr16_+_23652700 0.51 ENST00000300087.2
dynactin 5 (p25)
chr16_+_28834531 0.51 ENST00000570200.1
ataxin 2-like
chr3_+_19189946 0.51 ENST00000328405.2
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr9_-_136605042 0.50 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
sarcosine dehydrogenase
chrX_+_48334549 0.50 ENST00000019019.2
ENST00000348411.2
ENST00000396894.4
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr16_+_58010339 0.49 ENST00000290871.5
ENST00000441824.2
testis, prostate and placenta expressed
chr9_-_35619539 0.49 ENST00000396757.1
CD72 molecule
chr22_-_50946113 0.49 ENST00000216080.5
ENST00000474879.2
ENST00000380796.3
lipase maturation factor 2
chr4_+_15376165 0.48 ENST00000382383.3
ENST00000429690.1
C1q and tumor necrosis factor related protein 7
chr1_-_20987982 0.48 ENST00000375048.3
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr21_+_43823983 0.48 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr11_-_1330834 0.47 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
toll interacting protein
chr10_+_103113802 0.47 ENST00000370187.3
beta-transducin repeat containing E3 ubiquitin protein ligase
chrX_-_129244454 0.47 ENST00000308167.5
E74-like factor 4 (ets domain transcription factor)
chr1_-_114447620 0.47 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
adaptor-related protein complex 4, beta 1 subunit
chr19_-_10420459 0.46 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr17_-_79818354 0.46 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
prolyl 4-hydroxylase, beta polypeptide
chr17_+_21279509 0.45 ENST00000583088.1
potassium inwardly-rectifying channel, subfamily J, member 12
chr7_+_72742162 0.45 ENST00000431982.2
FK506 binding protein 6, 36kDa
chr5_-_179051579 0.45 ENST00000505811.1
ENST00000515714.1
ENST00000513225.1
ENST00000503664.1
ENST00000356731.5
ENST00000523137.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr22_-_38577731 0.45 ENST00000335539.3
phospholipase A2, group VI (cytosolic, calcium-independent)
chr20_+_816695 0.43 ENST00000246100.3
family with sequence similarity 110, member A
chrX_-_153637612 0.43 ENST00000369807.1
ENST00000369808.3
deoxyribonuclease I-like 1
chr1_-_114447683 0.43 ENST00000256658.4
ENST00000369564.1
adaptor-related protein complex 4, beta 1 subunit
chr5_-_64920115 0.43 ENST00000381018.3
ENST00000274327.7
tripartite motif containing 23
chr3_-_9005118 0.42 ENST00000264926.2
RAD18 homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
1.8 14.4 GO:0031642 negative regulation of myelination(GO:0031642)
1.4 4.3 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.2 4.9 GO:0035627 ceramide transport(GO:0035627)
1.2 3.6 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.0 4.0 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.0 2.9 GO:0042369 vitamin D catabolic process(GO:0042369)
0.9 2.7 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.9 4.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.8 3.9 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.7 2.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.6 2.4 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.6 3.5 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.5 1.5 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.5 1.5 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.5 2.5 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.5 1.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 0.5 GO:0051604 protein maturation(GO:0051604)
0.5 2.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 2.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.5 1.4 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.4 2.9 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.4 1.7 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4 8.7 GO:0016540 protein autoprocessing(GO:0016540)
0.4 6.2 GO:0051639 actin filament network formation(GO:0051639)
0.4 2.2 GO:0090131 mesenchyme migration(GO:0090131)
0.3 1.0 GO:1903521 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3 5.6 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 1.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 1.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 1.1 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.3 1.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 1.8 GO:0003383 apical constriction(GO:0003383)
0.3 4.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 4.4 GO:0046415 urate metabolic process(GO:0046415)
0.2 1.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 5.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.7 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.0 GO:0038127 epidermal growth factor receptor signaling pathway(GO:0007173) ERBB signaling pathway(GO:0038127)
0.2 0.2 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.2 0.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 2.0 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.2 1.5 GO:0090237 regulation of arachidonic acid secretion(GO:0090237)
0.2 3.9 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.2 0.5 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.6 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 1.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 2.2 GO:0035878 nail development(GO:0035878)
0.1 2.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 4.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.4 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 4.1 GO:0007398 ectoderm development(GO:0007398)
0.1 0.8 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 3.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.7 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 2.9 GO:0036010 protein localization to endosome(GO:0036010)
0.1 1.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.9 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.3 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
0.1 0.5 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.4 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.1 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.6 GO:0032439 endosome localization(GO:0032439)
0.1 1.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.1 2.9 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 0.6 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.1 0.2 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 5.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 1.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 1.6 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 1.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.1 GO:1902903 regulation of fibril organization(GO:1902903)
0.1 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 3.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.2 GO:0044828 negative regulation of CREB transcription factor activity(GO:0032792) negative regulation by host of viral genome replication(GO:0044828)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.4 GO:0018095 sperm axoneme assembly(GO:0007288) protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0018202 UTP biosynthetic process(GO:0006228) peptidyl-histidine modification(GO:0018202)
0.0 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 2.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.2 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 1.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.4 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 1.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 3.7 GO:0048477 oogenesis(GO:0048477)
0.0 4.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.3 GO:0097503 sialylation(GO:0097503)
0.0 1.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 1.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.7 GO:0060976 coronary vasculature development(GO:0060976)
0.0 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.7 GO:0036065 fucosylation(GO:0036065)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 3.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 3.0 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.8 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 2.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 4.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.4 GO:0034204 lipid translocation(GO:0034204)
0.0 1.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 1.1 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.3 GO:0007517 muscle organ development(GO:0007517)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0031523 Myb complex(GO:0031523)
0.7 4.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.6 2.9 GO:0035838 growing cell tip(GO:0035838)
0.4 2.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 2.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 1.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 8.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 0.7 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.2 0.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.2 4.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.2 GO:0005916 fascia adherens(GO:0005916)
0.1 1.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 10.0 GO:0045178 basal part of cell(GO:0045178)
0.1 2.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0000801 central element(GO:0000801)
0.1 0.9 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 2.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 3.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 5.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.6 GO:0031105 septin complex(GO:0031105)
0.1 2.5 GO:0031941 filamentous actin(GO:0031941)
0.1 1.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.9 GO:0000124 SAGA complex(GO:0000124)
0.0 4.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 2.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 2.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 4.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 31.3 GO:0005615 extracellular space(GO:0005615)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 2.0 GO:0005694 chromosome(GO:0005694)
0.0 0.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
1.2 4.9 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
1.2 7.3 GO:0045569 TRAIL binding(GO:0045569)
1.0 4.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 3.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.8 3.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.7 3.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.7 2.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.6 2.9 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.5 2.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 8.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.5 1.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.4 2.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 5.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 1.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 4.5 GO:0008199 ferric iron binding(GO:0008199)
0.3 4.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 2.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 1.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 5.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 3.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 4.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.2 0.5 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.2 0.7 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.2 1.5 GO:0043237 laminin-1 binding(GO:0043237)
0.2 0.5 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.4 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 2.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 3.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.8 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.0 GO:0004673 protein histidine kinase activity(GO:0004673)
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 2.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 1.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 2.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.9 GO:0089720 caspase binding(GO:0089720)
0.1 0.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 19.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 2.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.2 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.1 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0055103 ligase regulator activity(GO:0055103)
0.0 3.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 7.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.8 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.0 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 2.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 3.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.3 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 3.0 GO:0005496 steroid binding(GO:0005496)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 3.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.8 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.4 GO:0005261 cation channel activity(GO:0005261)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 23.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 9.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 7.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.8 PID AURORA B PATHWAY Aurora B signaling
0.1 3.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 4.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 4.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 4.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 4.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 5.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 4.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 3.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 3.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 2.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 2.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling