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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for VAX2_RHOXF2

Z-value: 0.43

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Transcription factors associated with VAX2_RHOXF2

Gene Symbol Gene ID Gene Info
ENSG00000116035.2 ventral anterior homeobox 2
ENSG00000131721.4 Rhox homeobox family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VAX2hg19_v2_chr2_+_71127699_711277440.291.3e-01Click!
RHOXF2hg19_v2_chrX_+_119292467_1192924670.001.0e+00Click!

Activity profile of VAX2_RHOXF2 motif

Sorted Z-values of VAX2_RHOXF2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_101661887 1.22 ENST00000311812.2
sorting nexin 31
chr1_-_152386732 1.10 ENST00000271835.3
cornulin
chr19_-_36001113 1.09 ENST00000434389.1
dermokine
chr9_+_125133315 0.84 ENST00000223423.4
ENST00000362012.2
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_+_130339710 0.77 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr8_-_91095099 0.75 ENST00000265431.3
calbindin 1, 28kDa
chr16_-_30122717 0.73 ENST00000566613.1
glycerophosphodiester phosphodiesterase domain containing 3
chr1_+_62439037 0.66 ENST00000545929.1
InaD-like (Drosophila)
chr4_-_69111401 0.59 ENST00000332644.5
transmembrane protease, serine 11B
chr11_-_5323226 0.57 ENST00000380224.1
olfactory receptor, family 51, subfamily B, member 4
chr17_-_40337470 0.57 ENST00000293330.1
hypocretin (orexin) neuropeptide precursor
chr3_-_141747950 0.56 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_+_56584414 0.49 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr9_+_125132803 0.49 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_+_7783859 0.48 ENST00000400120.3
zinc finger protein 705B
chr11_+_33061543 0.47 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr4_+_88896819 0.45 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr8_-_42623747 0.42 ENST00000534622.1
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr17_+_40610862 0.37 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr11_-_107729887 0.37 ENST00000525815.1
solute carrier family 35, member F2
chr15_-_89755034 0.34 ENST00000563254.1
retinaldehyde binding protein 1
chr6_+_34204642 0.34 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr19_+_11071546 0.33 ENST00000358026.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_-_211307404 0.32 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr11_-_121986923 0.32 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr13_-_36050819 0.31 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr12_+_26348246 0.30 ENST00000422622.2
sarcospan
chrX_-_21676442 0.30 ENST00000379499.2
kelch-like family member 34
chr11_-_111794446 0.29 ENST00000527950.1
crystallin, alpha B
chr7_-_121944491 0.29 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr1_-_169429690 0.28 ENST00000445428.1
RP1-206D15.3
chr2_-_40680578 0.27 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chrX_+_43515467 0.27 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr2_+_113763031 0.27 ENST00000259211.6
interleukin 36, alpha
chrX_+_7137475 0.26 ENST00000217961.4
steroid sulfatase (microsomal), isozyme S
chr10_+_6779326 0.24 ENST00000417112.1
RP11-554I8.2
chrX_-_18690210 0.23 ENST00000379984.3
retinoschisin 1
chr4_-_159956333 0.23 ENST00000434826.2
chromosome 4 open reading frame 45
chr9_+_12693336 0.22 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr12_-_118797475 0.22 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr6_+_53883708 0.22 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
muscular LMNA-interacting protein
chr1_+_54569968 0.21 ENST00000391366.1
Uncharacterized protein
chr7_-_100860851 0.21 ENST00000223127.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr12_-_10022735 0.20 ENST00000228438.2
C-type lectin domain family 2, member B
chr6_-_82957433 0.20 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr1_-_67266939 0.20 ENST00000304526.2
insulin-like 5
chr16_+_12059050 0.19 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr14_+_32798547 0.19 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr7_+_50348268 0.18 ENST00000438033.1
ENST00000439701.1
IKAROS family zinc finger 1 (Ikaros)
chr14_+_32798462 0.18 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr2_-_214016314 0.18 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr6_-_137494775 0.17 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
interleukin 22 receptor, alpha 2
chr2_+_169926047 0.17 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr1_-_201140673 0.17 ENST00000367333.2
transmembrane protein 9
chr2_+_90248739 0.16 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr1_+_46972668 0.16 ENST00000371956.4
ENST00000360032.3
diencephalon/mesencephalon homeobox 1
chr4_-_186696425 0.16 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr14_+_72399833 0.15 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr2_-_74619152 0.15 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr8_-_7243080 0.15 ENST00000400156.4
zinc finger protein 705G
chr6_+_29079668 0.15 ENST00000377169.1
olfactory receptor, family 2, subfamily J, member 3
chr21_-_37914898 0.14 ENST00000399136.1
claudin 14
chr17_-_18430160 0.14 ENST00000392176.3
family with sequence similarity 106, member A
chr12_+_26348429 0.14 ENST00000242729.2
sarcospan
chr15_+_58430567 0.13 ENST00000536493.1
aquaporin 9
chr7_-_111032971 0.13 ENST00000450877.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr4_-_77328458 0.13 ENST00000388914.3
ENST00000434846.2
coiled-coil domain containing 158
chr2_-_89292422 0.13 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr17_-_38545799 0.13 ENST00000577541.1
topoisomerase (DNA) II alpha 170kDa
chr4_+_88754113 0.13 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr15_+_58430368 0.12 ENST00000558772.1
ENST00000219919.4
aquaporin 9
chr17_-_33390667 0.12 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr14_+_103851712 0.12 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MAP/microtubule affinity-regulating kinase 3
chr6_-_133035185 0.12 ENST00000367928.4
vanin 1
chr4_+_88571429 0.12 ENST00000339673.6
ENST00000282479.7
dentin matrix acidic phosphoprotein 1
chr4_+_151503077 0.11 ENST00000317605.4
mab-21-like 2 (C. elegans)
chr20_-_50722183 0.11 ENST00000371523.4
ZFP64 zinc finger protein
chrX_-_77225135 0.11 ENST00000458128.1
phosphoglycerate mutase family member 4
chr7_-_44122063 0.11 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
polymerase (DNA directed), mu
chr18_-_67624160 0.10 ENST00000581982.1
ENST00000280200.4
CD226 molecule
chr4_+_70796784 0.10 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr14_-_39639523 0.10 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
trafficking protein particle complex 6B
chr12_-_10955226 0.10 ENST00000240687.2
taste receptor, type 2, member 7
chr15_+_58702742 0.09 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr2_-_74618964 0.09 ENST00000417090.1
ENST00000409868.1
dynactin 1
chr8_+_92261516 0.09 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr14_-_53258314 0.09 ENST00000216410.3
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr3_+_115342349 0.09 ENST00000393780.3
growth associated protein 43
chr3_+_186353756 0.09 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
fetuin B
chr10_-_92681033 0.08 ENST00000371697.3
ankyrin repeat domain 1 (cardiac muscle)
chr18_-_44181442 0.08 ENST00000398722.4
lipoxygenase homology domains 1
chr20_-_33735070 0.08 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr4_+_169418255 0.08 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr19_-_3557570 0.08 ENST00000355415.2
major facilitator superfamily domain containing 12
chr5_+_89770664 0.08 ENST00000503973.1
ENST00000399107.1
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr5_+_89770696 0.08 ENST00000504930.1
ENST00000514483.1
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr17_-_39203519 0.08 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr10_-_99205607 0.07 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr12_-_22063787 0.07 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr11_-_117747434 0.07 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr11_-_117747607 0.07 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr15_+_80351910 0.07 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr7_+_120628731 0.07 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr7_+_12727250 0.07 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr5_-_149829244 0.07 ENST00000312037.5
ribosomal protein S14
chr11_-_117748138 0.07 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr7_+_100860949 0.06 ENST00000305105.2
zinc finger, HIT-type containing 1
chr6_+_167536230 0.06 ENST00000341935.5
ENST00000349984.4
chemokine (C-C motif) receptor 6
chr7_+_6655225 0.06 ENST00000457543.3
zinc finger protein 853
chr3_+_185431080 0.06 ENST00000296270.1
chromosome 3 open reading frame 65
chr1_-_24151903 0.06 ENST00000436439.2
ENST00000374490.3
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr10_+_99205959 0.06 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr10_+_99205894 0.06 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr10_-_17171817 0.06 ENST00000377833.4
cubilin (intrinsic factor-cobalamin receptor)
chr10_+_18549645 0.06 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr10_-_50396407 0.06 ENST00000374153.2
ENST00000374151.3
chromosome 10 open reading frame 128
chr16_+_69345243 0.05 ENST00000254950.11
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr3_+_157154578 0.05 ENST00000295927.3
pentraxin 3, long
chr5_-_149829294 0.05 ENST00000401695.3
ribosomal protein S14
chr5_+_121297650 0.05 ENST00000339397.4
serum response factor binding protein 1
chr4_+_80584903 0.05 ENST00000506460.1
RP11-452C8.1
chr3_-_151034734 0.05 ENST00000260843.4
G protein-coupled receptor 87
chr5_-_149829314 0.05 ENST00000407193.1
ribosomal protein S14
chr3_-_112127981 0.04 ENST00000486726.2
RP11-231E6.1
chrX_+_153533275 0.04 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
transketolase-like 1
chr9_-_21202204 0.04 ENST00000239347.3
interferon, alpha 7
chr21_+_17443521 0.04 ENST00000456342.1
long intergenic non-protein coding RNA 478
chr6_+_3259148 0.03 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome (prosome, macropain) assembly chaperone 4
chr5_+_176811431 0.03 ENST00000512593.1
ENST00000324417.5
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr17_-_38821373 0.03 ENST00000394052.3
keratin 222
chr20_-_29978383 0.03 ENST00000339144.3
ENST00000376321.3
defensin, beta 119
chr15_+_80351977 0.03 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
zinc finger, AN1-type domain 6
chr12_-_78753496 0.03 ENST00000548512.1
RP11-38F22.1
chr11_+_60383204 0.03 ENST00000412599.1
ENST00000320202.4
long intergenic non-protein coding RNA 301
chrX_-_70326455 0.03 ENST00000374251.5
chromosome X open reading frame 65
chr4_-_138453606 0.03 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr19_+_12175504 0.03 ENST00000439326.3
zinc finger protein 844
chr21_+_17442799 0.03 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
long intergenic non-protein coding RNA 478
chr7_-_92777606 0.02 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr1_+_75600567 0.02 ENST00000356261.3
LIM homeobox 8
chr12_+_82347498 0.02 ENST00000550506.1
RP11-362A1.1
chr14_+_22670455 0.02 ENST00000390460.1
T cell receptor alpha variable 26-2
chr7_+_115862858 0.02 ENST00000393481.2
testis derived transcript (3 LIM domains)
chr12_-_50643664 0.02 ENST00000550592.1
LIM domain and actin binding 1
chr12_+_16500037 0.02 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr17_+_43238438 0.02 ENST00000593138.1
ENST00000586681.1
hexamethylene bis-acetamide inducible 2
chr1_-_190446759 0.02 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr16_-_55866997 0.01 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr9_-_95166841 0.01 ENST00000262551.4
osteoglycin
chr21_+_17443434 0.01 ENST00000400178.2
long intergenic non-protein coding RNA 478
chr9_-_95166884 0.01 ENST00000375561.5
osteoglycin
chr12_-_6233828 0.00 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr16_+_72088376 0.00 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr7_-_44580861 0.00 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 0.5 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.7 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.3 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases