Motif ID: EP300.p2

Z-value: 0.039


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EP300chr22_+_41487787-0.782.2e-02Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_54867372 0.971 NM_144594
GTSF1
gametocyte specific factor 1
chr10_-_21462987 0.577 NEBL
nebulette
chr1_-_161008733 0.526 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr6_+_89790412 0.401 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr10_-_21463019 0.377 NM_001173484
NM_213569
NEBL

nebulette

chr19_+_16296211 0.367 NM_014077
FAM32A
family with sequence similarity 32, member A
chr6_+_89790464 0.366 PNRC1
proline-rich nuclear receptor coactivator 1
chr10_+_111985628 0.354 NM_005962
MXI1
MAX interactor 1
chr5_-_149535309 0.320 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_+_122793061 0.308 NM_181794
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chrX_-_140271293 0.299 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr12_+_72057676 0.289 NM_031435
THAP2
THAP domain containing, apoptosis associated protein 2
chr6_-_31698033 0.277 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr2_-_99224868 0.271 NM_001008215
COA5
cytochrome C oxidase assembly factor 5
chr2_-_27294491 0.269 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr1_+_26146446 0.266 FAM54B
family with sequence similarity 54, member B
chr15_-_81616439 0.265 NM_181900
STARD5
StAR-related lipid transfer (START) domain containing 5
chr11_-_93276513 0.263 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr6_+_46655611 0.261 NM_001010870
NM_001168359
TDRD6

tudor domain containing 6

chr15_-_82338348 0.260 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr3_+_169755733 0.256 NM_014373
GPR160
G protein-coupled receptor 160
chr1_+_184356186 0.255 C1orf21
chromosome 1 open reading frame 21
chr22_+_27053392 0.251 MIAT
myocardial infarction associated transcript (non-protein coding)
chr6_-_31697953 0.246 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr3_+_169755782 0.246 GPR160
G protein-coupled receptor 160
chr15_-_82338459 0.244 MEX3B
mex-3 homolog B (C. elegans)
chr16_-_67260720 0.240 NM_012163
LRRC29
leucine rich repeat containing 29
chr5_-_149535138 0.236 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_+_26146622 0.235 NM_019557
FAM54B
family with sequence similarity 54, member B
chr19_-_49828434 0.234 NM_014037
SLC6A16
solute carrier family 6, member 16
chr2_+_217498082 0.229 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chrX_-_140271275 0.227 LDOC1
leucine zipper, down-regulated in cancer 1
chrX_+_135229536 0.222 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr6_+_72596405 0.218 RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_47082529 0.218 NM_201403
MOB3C
MOB kinase activator 3C
chr5_+_56111379 0.212 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr19_-_1401474 0.209 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr1_-_23694497 0.205 NM_030634
ZNF436
zinc finger protein 436
chr9_-_98270321 0.203 NM_001083604
NM_001083605
PTCH1

patched 1

chr19_+_19627018 0.201 NM_015965
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr1_+_184356227 0.200 C1orf21
chromosome 1 open reading frame 21
chr16_-_10275743 0.200 NM_001134408
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr12_+_70759974 0.199 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr11_+_47269850 0.198 NM_001251934
NM_001251935
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr11_-_104035023 0.198 NM_025208
NM_033135
PDGFD

platelet derived growth factor D

chr11_-_104905849 0.196 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr1_+_26146376 0.195 NM_001099625
NM_001099627
FAM54B

family with sequence similarity 54, member B

chr8_+_123794043 0.194 ZHX2
zinc fingers and homeoboxes 2
chr4_-_84030995 0.192 NM_001130716
PLAC8
placenta-specific 8
chr2_+_74153987 0.191 DGUOK
deoxyguanosine kinase
chr7_+_142552547 0.191 NM_004445
EPHB6
EPH receptor B6
chr15_+_65134081 0.190 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr10_-_81205091 0.190 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr11_-_104034685 0.188 PDGFD
platelet derived growth factor D
chr5_-_81046943 0.185 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr11_+_706607 0.183 EPS8L2
EPS8-like 2
chr2_-_25016214 0.183 NM_001013663
PTRHD1
peptidyl-tRNA hydrolase domain containing 1
chr2_+_74154015 0.182 DGUOK
deoxyguanosine kinase
chr2_+_74685526 0.180 NM_012477
WBP1
WW domain binding protein 1
chr6_-_31697568 0.179 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_-_184006491 0.177 GLT25D2
glycosyltransferase 25 domain containing 2
chr15_+_42787850 0.177 SNAP23
synaptosomal-associated protein, 23kDa
chr10_-_105212149 0.176 NM_015916
CALHM2
calcium homeostasis modulator 2
chr10_+_120789227 0.175 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr2_+_74153931 0.175 NM_080916
NM_080918
DGUOK

deoxyguanosine kinase

chr3_-_51996855 0.175 NM_033010
PCBP4
poly(rC) binding protein 4
chr12_-_51717941 0.174 BIN2
bridging integrator 2
chr16_+_85646923 0.174 NM_014615
KIAA0182
KIAA0182
chr1_-_46598250 0.173 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr7_-_150974179 0.173 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_68516311 0.173 NM_004675
DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr11_-_77899640 0.172 NM_001029859
KCTD21
potassium channel tetramerisation domain containing 21
chr7_-_93633527 0.172 NM_005868
BET1
blocked early in transport 1 homolog (S. cerevisiae)
chr11_-_130184314 0.171 ZBTB44
zinc finger and BTB domain containing 44
chr2_+_30369868 0.171 YPEL5
yippee-like 5 (Drosophila)
chr13_-_114103452 0.168 NM_199162
ADPRHL1
ADP-ribosylhydrolase like 1
chr11_-_2925174 0.168 NM_007105
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr8_+_17434700 0.167 PDGFRL
platelet-derived growth factor receptor-like
chr17_-_19290471 0.167 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr16_-_2336874 0.167


chr11_-_46722160 0.166 ARHGAP1
Rho GTPase activating protein 1
chr13_+_42031525 0.164 NM_014059
C13orf15
chromosome 13 open reading frame 15
chr17_+_78388979 0.163 ENDOV
endonuclease V
chr13_+_42031679 0.162 C13orf15
chromosome 13 open reading frame 15
chr19_-_3047632 0.162 NM_001144761
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr1_-_161008710 0.161 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr3_-_151987332 0.161 LOC401093
uncharacterized LOC401093
chr20_+_44034632 0.161 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr17_+_43238263 0.161 NM_144608
HEXIM2
hexamethylene bis-acetamide inducible 2
chr21_+_27011588 0.160 NM_021219
JAM2
junctional adhesion molecule 2
chr11_-_46722139 0.159 ARHGAP1
Rho GTPase activating protein 1
chr4_-_142054431 0.159 NM_020724
RNF150
ring finger protein 150
chr15_-_68724434 0.158 NM_001004439
ITGA11
integrin, alpha 11
chr2_+_23608297 0.158 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr13_+_42031690 0.155 C13orf15
chromosome 13 open reading frame 15
chr1_+_38022514 0.154 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr11_-_120008738 0.152 TRIM29
tripartite motif containing 29
chr5_+_139028483 0.152 CXXC5
CXXC finger protein 5
chr20_-_30311693 0.151 BCL2L1
BCL2-like 1
chr22_-_29137776 0.150 NM_001005735
NM_007194
NM_145862
CHEK2


checkpoint kinase 2


chrX_-_107019001 0.148 NM_198057
TSC22D3
TSC22 domain family, member 3
chr3_-_18480203 0.147 NM_001131010
SATB1
SATB homeobox 1
chr5_-_176936857 0.146 NM_024872
DOK3
docking protein 3
chr19_+_47104389 0.146 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr2_+_24346339 0.146 NM_001145710
LOC375190
UPF0638 protein B
chr1_-_54871681 0.146 SSBP3
single stranded DNA binding protein 3
chr17_-_74582144 0.145 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr3_+_12838170 0.145 NM_001162499
NM_012298
CAND2

cullin-associated and neddylation-dissociated 2 (putative)

chr17_+_73043319 0.144 KCTD2
potassium channel tetramerisation domain containing 2
chr17_+_38230678 0.143 THRA
thyroid hormone receptor, alpha
chr19_+_18530423 0.143


chr19_-_49149252 0.143 NM_001217
CA11
carbonic anhydrase XI
chr5_-_176936834 0.143 DOK3
docking protein 3
chrX_+_135251454 0.142 NM_001159704
FHL1
four and a half LIM domains 1
chr17_+_78388944 0.142 NM_001164637
NM_001164638
NM_173627
ENDOV


endonuclease V


chr15_-_90437171 0.142 AP3S2
adaptor-related protein complex 3, sigma 2 subunit
chr18_-_74207145 0.141 NM_014643
ZNF516
zinc finger protein 516
chr19_-_17516383 0.141 NM_004335
BST2
bone marrow stromal cell antigen 2
chr2_-_229046313 0.140 NM_001142644
NM_030623
SPHKAP

SPHK1 interactor, AKAP domain containing

chr11_-_120008219 0.140 TRIM29
tripartite motif containing 29
chr21_+_27011766 0.140 JAM2
junctional adhesion molecule 2
chr22_+_42475732 0.138 C22orf32
chromosome 22 open reading frame 32
chr1_-_161102367 0.137 DEDD
death effector domain containing
chr11_-_119999516 0.137 TRIM29
tripartite motif containing 29
chr12_-_48744553 0.136 NM_001172681
NM_152320
ZNF641

zinc finger protein 641

chr19_+_9473695 0.136 NM_003451
ZNF177
zinc finger protein 177
chr9_+_130186652 0.135 NM_007135
ZNF79
zinc finger protein 79
chr2_+_233415300 0.135 NM_004846
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chrX_-_107018889 0.135 TSC22D3
TSC22 domain family, member 3
chr3_-_178789535 0.134 ZMAT3
zinc finger, matrin-type 3
chr20_+_44035203 0.133 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr2_+_71295685 0.133 NAGK
N-acetylglucosamine kinase
chr18_+_66382490 0.132 NM_001093729
CCDC102B
coiled-coil domain containing 102B
chr16_-_31085503 0.132 NM_024706
ZNF668
zinc finger protein 668
chr21_-_38639625 0.132 NM_006052
DSCR3
Down syndrome critical region gene 3
chr15_+_74218786 0.131 NM_005576
LOXL1
lysyl oxidase-like 1
chr21_-_45759234 0.130 C21orf2
chromosome 21 open reading frame 2
chr6_-_111136330 0.130 CDK19
cyclin-dependent kinase 19
chr8_+_123793894 0.130 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr2_+_39892637 0.129 NM_001167959
TMEM178
transmembrane protein 178
chr10_-_45496259 0.128 NM_001039380
C10orf25
chromosome 10 open reading frame 25
chr11_-_120008801 0.127 TRIM29
tripartite motif containing 29
chr15_+_74218794 0.127 LOXL1
lysyl oxidase-like 1
chr12_+_7942025 0.127 NANOG
Nanog homeobox
chr21_-_38639593 0.127 DSCR3
Down syndrome critical region gene 3
chr1_+_6086072 0.127 NM_003636
NM_172130
KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr11_+_64001974 0.127 NM_001243733
NM_003377
VEGFB

vascular endothelial growth factor B

chr2_+_217498205 0.126 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr4_-_156874993 0.126 NM_001334
CTSO
cathepsin O
chr22_+_42475661 0.126 NM_033318
C22orf32
chromosome 22 open reading frame 32
chr20_+_34680569 0.126 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr5_+_119799898 0.125 PRR16
proline rich 16
chr9_-_130667571 0.124 LOC100131355
ST6GALNAC6
uncharacterized LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_161102457 0.124 NM_001039711
NM_032998
DEDD

death effector domain containing

chr19_-_54984341 0.124 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr11_-_34535302 0.123 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr19_-_1605462 0.123 UQCR11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr6_-_40555111 0.122 NM_020737
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr8_-_91657898 0.122 NM_001008495
NM_001146273
TMEM64

transmembrane protein 64

chr10_-_64578926 0.122 NM_001136178
EGR2
early growth response 2
chr11_-_67205151 0.121 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr19_+_11039419 0.121 NM_138358
C19orf52
chromosome 19 open reading frame 52
chr9_-_115774471 0.120 NM_001101338
ZNF883
zinc finger protein 883
chr8_+_145159304 0.120 NM_032272
MAF1
MAF1 homolog (S. cerevisiae)
chr1_+_236558715 0.119 NM_080738
EDARADD
EDAR-associated death domain
chrX_+_70315637 0.119 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr10_-_127511795 0.119 UROS
uroporphyrinogen III synthase
chr17_-_74581881 0.119 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr15_+_74218811 0.119 LOXL1
lysyl oxidase-like 1
chr7_+_128864740 0.119 NM_001130720
NM_015328
AHCYL2

adenosylhomocysteinase-like 2

chr22_+_24577417 0.119 SUSD2
sushi domain containing 2
chr10_+_81892497 0.119 PLAC9
placenta-specific 9
chr8_+_356807 0.119 NM_012173
NM_183420
NM_183421
FBXO25


F-box protein 25


chr1_+_221052735 0.118 NM_021958
HLX
H2.0-like homeobox
chr5_-_149535420 0.118 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_+_3541587 0.118 TPRG1L
tumor protein p63 regulated 1-like
chr17_+_7342688 0.118 NM_004112
FGF11
fibroblast growth factor 11
chr20_+_62688438 0.118 NM_198723
TCEA2
transcription elongation factor A (SII), 2
chr11_+_67250595 0.118 AIP
aryl hydrocarbon receptor interacting protein
chr15_-_93616358 0.118 NM_001166286
RGMA
RGM domain family, member A
chr7_-_45128492 0.118 NM_001146334
NACAD
NAC alpha domain containing
chr12_-_63328663 0.115 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr12_-_92539614 0.115 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr22_-_19435211 0.115 C22orf39
HIRA
chromosome 22 open reading frame 39
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_+_111415721 0.114 NM_000560
CD53
CD53 molecule
chr11_-_63933493 0.114 NM_014067
MACROD1
MACRO domain containing 1
chr11_+_134094565 0.114 VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr15_-_93616308 0.114 RGMA
RGM domain family, member A
chr3_+_134514300 0.113 EPHB1
EPH receptor B1
chr1_-_173886401 0.113 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr9_+_130186714 0.113 ZNF79
zinc finger protein 79
chr11_+_2924504 0.113 SLC22A18
solute carrier family 22, member 18
chr15_+_74287132 0.112 PML
promyelocytic leukemia
chr16_-_66952729 0.112 NM_001204744
NM_001204745
NM_001204746
NM_004062
CDH16



cadherin 16, KSP-cadherin



chr8_+_145159398 0.112 MAF1
MAF1 homolog (S. cerevisiae)
chr7_+_130126035 0.111 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr5_+_119800004 0.111 NM_016644
PRR16
proline rich 16
chr1_-_161102210 0.111 NM_001039712
DEDD
death effector domain containing
chr3_+_52279742 0.111 NM_144641
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr14_-_68141205 0.110 VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 9.45e-05 GO:0050794 regulation of cellular process
1.11 1.43e-03 GO:0050789 regulation of biological process
1.38 1.96e-03 GO:0032774 RNA biosynthetic process
1.10 5.82e-03 GO:0065007 biological regulation
1.98 9.56e-03 GO:0006184 GTP catabolic process
1.94 1.07e-02 GO:0046039 GTP metabolic process
1.57 1.22e-02 GO:0007264 small GTPase mediated signal transduction
1.06 1.84e-02 GO:0009987 cellular process
1.71 3.52e-02 GO:0030168 platelet activation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 5.71e-12 GO:0005622 intracellular
1.10 3.49e-11 GO:0044424 intracellular part
1.12 4.41e-08 GO:0005737 cytoplasm
1.31 2.16e-07 GO:0005829 cytosol
1.15 1.74e-05 GO:0005634 nucleus
3.83 3.69e-03 GO:0031201 SNARE complex
1.07 1.08e-02 GO:0043229 intracellular organelle
1.07 1.22e-02 GO:0043226 organelle
1.10 3.92e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 7.32e-07 GO:0005515 protein binding
1.07 1.11e-04 GO:0005488 binding
1.31 2.03e-02 GO:0001071 nucleic acid binding transcription factor activity
1.31 2.03e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.20 3.80e-02 GO:0008270 zinc ion binding