Motif ID: ACCCUGU

Z-value: 0.401


Mature miRNA associated with seed ACCCUGU:

NamemiRBase Accession
hsa-miR-10a MIMAT0000253
hsa-miR-10b MIMAT0000254



Activity profile for motif ACCCUGU.

activity profile for motif ACCCUGU


Sorted Z-values histogram for motif ACCCUGU

Sorted Z-values for motif ACCCUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACCCUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_166711842 0.198 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr9_-_23826062 0.163 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr5_+_149151502 0.152 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr5_+_149109814 0.148 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr9_-_23821477 0.147 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_44365019 0.146 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr9_-_23821842 0.142 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr22_+_51113069 0.114 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr1_-_19282773 0.085 NM_001136265
IFFO2
intermediate filament family orphan 2
chr6_+_15246299 0.084 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr2_-_20425166 0.084 NM_001006946
SDC1
syndecan 1
chr2_+_97426571 0.082 NM_020184
CNNM4
cyclin M4
chr2_-_20424627 0.076 NM_002997
SDC1
syndecan 1
chrX_+_49832214 0.076 NM_000084
CLCN5
chloride channel 5
chr8_-_66701175 0.076 NM_002603
PDE7A
phosphodiesterase 7A
chr22_+_23522551 0.069 NM_004327
NM_021574
BCR

breakpoint cluster region

chr4_-_66535652 0.064 NM_004439
NM_182472
EPHA5

EPH receptor A5

chrX_+_49687212 0.062 NM_001127898
NM_001127899
CLCN5

chloride channel 5

chr2_+_64681270 0.057 NM_014181
LGALSL
lectin, galactoside-binding-like
chr7_-_92463211 0.056 NM_001259
CDK6
cyclin-dependent kinase 6
chr9_+_112403067 0.055 NM_001037293
PALM2
paralemmin 2
chr1_-_9970265 0.053 NM_001012329
NM_020248
CTNNBIP1

catenin, beta interacting protein 1

chr15_+_42066631 0.053 NM_001128608
NM_014994
MAPKBP1

mitogen-activated protein kinase binding protein 1

chr18_+_43914186 0.053 NM_152470
RNF165-IT1
RNF165
RNF165 intronic transcript 1 (non-protein coding)
ring finger protein 165
chr16_+_50186809 0.051 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr8_-_66753968 0.051 NM_001242318
PDE7A
phosphodiesterase 7A
chr20_+_55204307 0.050 NM_003222
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr12_-_77459198 0.049 NM_203394
E2F7
E2F transcription factor 7
chr12_-_85306579 0.049 NM_001146335
NM_018057
NM_182767
SLC6A15


solute carrier family 6 (neutral amino acid transporter), member 15


chr17_-_46651809 0.049 NM_002146
HOXB3
homeobox B3
chr10_-_61900659 0.048 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_216896640 0.046 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr7_-_92465929 0.045 NM_001145306
CDK6
cyclin-dependent kinase 6
chr1_-_217311095 0.045 NM_001134285
ESRRG
estrogen-related receptor gamma
chr4_+_154125589 0.044 NM_015271
TRIM2
tripartite motif containing 2
chr10_-_62332666 0.044 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_217262946 0.043 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr10_-_62149487 0.043 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_206950895 0.042 NM_017759
INO80D
INO80 complex subunit D
chr17_-_7518124 0.042 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr15_-_56209305 0.041 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr7_-_138665853 0.040 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr10_-_128994421 0.039 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr11_+_66024746 0.038 NM_001134775
KLC2
kinesin light chain 2
chr17_-_29151724 0.038 NM_015986
CRLF3
cytokine receptor-like factor 3
chr4_+_154074269 0.037 NM_001130067
TRIM2
tripartite motif containing 2
chr18_+_19749403 0.034 NM_005257
GATA6
GATA binding protein 6
chr22_+_40573879 0.032 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr19_+_13229101 0.031 NM_052876
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr8_+_22853360 0.030 NM_001160037
RHOBTB2
Rho-related BTB domain containing 2
chr8_+_22844918 0.030 NM_001160036
RHOBTB2
Rho-related BTB domain containing 2
chr3_+_238274 0.030 NM_001253387
NM_006614
CHL1

cell adhesion molecule with homology to L1CAM (close homolog of L1)

chr2_-_69870976 0.030 NM_014911
AAK1
AP2 associated kinase 1
chr18_-_33647336 0.029 NM_018170
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr1_-_39338976 0.028 NM_012333
MYCBP
c-myc binding protein
chr3_-_142166782 0.027 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr10_-_62493282 0.026 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_11047253 0.025 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr11_+_66025070 0.025 NM_001134776
NM_001134774
NM_022822
KLC2


kinesin light chain 2


chr18_+_33234532 0.023 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr5_-_89770432 0.023 NM_203406
MBLAC2
metallo-beta-lactamase domain containing 2
chr8_+_22857063 0.022 NM_015178
RHOBTB2
Rho-related BTB domain containing 2
chr14_-_47812394 0.022 NM_182830
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr8_+_1449531 0.022 NM_004745
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr7_+_20370724 0.022 NM_002214
ITGB8
integrin, beta 8
chr12_+_125811161 0.021 NM_052907
TMEM132B
transmembrane protein 132B
chr9_-_104500861 0.021 NM_133445
GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr6_-_11044354 0.021 NM_017770
ELOVL2
ELOVL fatty acid elongase 2
chr1_+_204913353 0.021 NM_001160331
NFASC
neurofascin
chr12_-_30830143 0.020 NM_001190995
IPO8
importin 8
chr2_+_166326156 0.020 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr15_-_72598655 0.020 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr22_+_40440664 0.019 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr2_-_160472960 0.019 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr2_+_166428845 0.018 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_+_5019048 0.017 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr14_+_23775970 0.017 NM_001199864
NM_004050
NM_001199839
BCL2L2-PABPN1
BCL2L2

BCL2L2-PABPN1 readthrough
BCL2-like 2

chr9_+_129567260 0.016 NM_001135776
NM_014007
ZBTB43

zinc finger and BTB domain containing 43

chr9_+_100263461 0.016 NM_001166116
TMOD1
tropomodulin 1
chr19_+_1407531 0.016 NM_018959
NM_170711
DAZAP1

DAZ associated protein 1

chr1_+_26758772 0.016 NM_001243564
NM_001243565
NM_024887
NM_205861
DHDDS



dehydrodolichyl diphosphate synthase



chr12_-_114843888 0.016 NM_181486
TBX5
T-box 5
chr20_-_5591487 0.016 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr2_-_164592512 0.016 NM_018086
FIGN
fidgetin
chr9_+_100263818 0.016 NM_003275
TMOD1
tropomodulin 1
chr1_+_28052467 0.015 NM_001143912
NM_001143913
NM_001143914
NM_001143915
NM_152660
FAM76A




family with sequence similarity 76, member A




chrX_-_129402753 0.015 NM_017666
ZNF280C
zinc finger protein 280C
chr2_+_10184371 0.015 NM_001177718
KLF11
Kruppel-like factor 11
chr12_+_4918341 0.014 NM_002235
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr9_-_95527002 0.014 NM_001003800
NM_015250
BICD2

bicaudal D homolog 2 (Drosophila)

chr17_-_56084656 0.014 NM_001078166
NM_006924
SRSF1

serine/arginine-rich splicing factor 1

chr9_-_74979829 0.013 NM_001102420
NM_001102421
NM_006007
ZFAND5


zinc finger, AN1-type domain 5


chr3_+_14989076 0.013 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr12_-_114846191 0.013 NM_000192
NM_080717
TBX5

T-box 5

chr2_+_238536183 0.013 NM_001137550
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr3_+_48956272 0.012 NM_006321
ARIH2
ariadne homolog 2 (Drosophila)
chr1_+_199996729 0.012 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr3_-_185655833 0.011 NM_001243879
NM_004593
TRA2B

transformer 2 beta homolog (Drosophila)

chr7_-_106301329 0.011 NM_175884
C7orf74
chromosome 7 open reading frame 74
chr12_-_125052009 0.010 NM_001077261
NM_001206654
NM_006312
NCOR2


nuclear receptor corepressor 2


chrX_-_73834460 0.010 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr15_-_72612247 0.010 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr15_-_56285732 0.010 NM_006154
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr8_-_41522724 0.010 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr7_-_27159213 0.010 NM_030661
HOXA3
homeobox A3
chr17_-_73775822 0.010 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr10_+_98592658 0.010 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr7_-_93189121 0.010 NM_001164738
CALCR
calcitonin receptor
chr15_-_72612497 0.009 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr13_-_27745952 0.009 NM_182488
USP12
ubiquitin specific peptidase 12
chr19_-_55954229 0.009 NM_001145176
SHISA7
shisa homolog 7 (Xenopus laevis)
chr17_+_18218569 0.009 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr10_-_121632265 0.009 NM_024834
MCMBP
minichromosome maintenance complex binding protein
chr4_+_3076236 0.008 NM_002111
HTT
huntingtin
chr17_-_76778306 0.008 NM_004762
NM_017456
CYTH1

cytohesin 1

chr22_+_45560529 0.008 NM_153645
NUP50
nucleoporin 50kDa
chr12_-_30848805 0.008 NM_006390
IPO8
importin 8
chr22_+_45559725 0.008 NM_007172
NUP50
nucleoporin 50kDa
chr7_-_27166638 0.008 NM_153631
HOXA3
homeobox A3
chr21_-_32931289 0.008 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr8_-_41655139 0.007 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr6_+_116421970 0.007 NM_152729
NT5DC1
5'-nucleotidase domain containing 1
chr4_+_184020343 0.006 NM_024949
WWC2
WW and C2 domain containing 2
chr4_-_53525316 0.006 NM_022832
USP46
ubiquitin specific peptidase 46
chr9_+_112542496 0.005 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr16_-_70719854 0.005 NM_138383
MTSS1L
metastasis suppressor 1-like
chrX_-_80065182 0.005 NM_153252
BRWD3
bromodomain and WD repeat domain containing 3
chr1_-_20141593 0.005 NM_019062
RNF186
ring finger protein 186
chr7_+_100081549 0.005 NM_173564
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr17_+_36861857 0.005 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_+_176981491 0.005 NM_002148
HOXD10
homeobox D10
chr5_-_45696219 0.005 NM_021072
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr7_-_93204035 0.004 NM_001164737
NM_001742
CALCR

calcitonin receptor

chr10_-_88281515 0.004 NM_015045
WAPAL
wings apart-like homolog (Drosophila)
chr14_-_48144156 0.004 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chrX_-_130423387 0.004 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr14_+_33408458 0.004 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr12_-_54653317 0.004 NM_001127322
CBX5
chromobox homolog 5
chr19_+_10531128 0.003 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_-_5463176 0.003 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr2_+_208394615 0.003 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr19_+_19496629 0.002 NM_017660
GATAD2A
GATA zinc finger domain containing 2A
chrX_-_41782230 0.002 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr1_-_38230804 0.002 NM_001099439
NM_173641
EPHA10

EPH receptor A10

chr22_+_39898248 0.001 NM_019008
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like
chr12_-_54653369 0.001 NM_001127321
CBX5
chromobox homolog 5
chr3_+_107241782 0.001 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr1_-_44820935 0.001 NM_024066
ERI3
ERI1 exoribonuclease family member 3
chr1_+_224301790 0.001 NM_001136115
NM_015176
FBXO28

F-box protein 28

chr18_-_45456925 0.000 NM_005901
SMAD2
SMAD family member 2
chr8_-_4852262 0.000 NM_033225
CSMD1
CUB and Sushi multiple domains 1
chr19_+_13105970 0.000 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_-_25902639 0.000 NM_022659
EBF2
early B-cell factor 2
chr19_+_10563581 0.000 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_-_56110851 0.000 NM_032836
FIZ1
FLT3-interacting zinc finger 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.60 2.69e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.35 4.49e-04 GO:0010468 regulation of gene expression
2.42 8.84e-04 GO:0051252 regulation of RNA metabolic process
2.34 1.19e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.43 1.24e-03 GO:0006355 regulation of transcription, DNA-dependent
2.28 2.10e-03 GO:0010556 regulation of macromolecule biosynthetic process
2.18 3.53e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.18 3.53e-03 GO:0031326 regulation of cellular biosynthetic process
2.16 4.49e-03 GO:0009889 regulation of biosynthetic process
2.12 6.71e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.47 1.72e-02 GO:0065007 biological regulation
4.37 2.15e-02 GO:0032583 regulation of gene-specific transcription
4.71 2.64e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.90 2.76e-02 GO:0060255 regulation of macromolecule metabolic process
4.04 4.40e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.45 2.24e-02 GO:0005654 nucleoplasm
3.04 3.37e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.20 1.26e-05 GO:0003676 nucleic acid binding
3.66 1.33e-05 GO:0030528 transcription regulator activity
2.26 1.04e-03 GO:0003677 DNA binding
1.27 3.07e-03 GO:0005488 binding
2.90 9.39e-03 GO:0001071 nucleic acid binding transcription factor activity
2.90 9.39e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
105.22 1.60e-02 GO:0050682 AF-2 domain binding