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Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 1.796

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_+_102104941	5.194	NM_004791	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr5_-_111312522	3.077	NM_001142474 NM_001142475	C5orf13	chromosome 5 open reading frame 13
chr5_+_156696351	2.992	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr12_-_91576579	2.847		DCN	decorin
chr12_-_91576805	2.804	NM_001920	DCN	decorin
chrX_+_85517970	2.726	NM_001139515	DACH2	dachshund homolog 2 (Drosophila)
chr2_+_189839132	2.301		COL3A1	collagen, type III, alpha 1
chr9_-_95186559	2.216	NM_005014	OMD	osteomodulin
chr3_+_69812961	2.167	NM_006722	MITF	microphthalmia-associated transcription factor
chr4_+_70916158	2.034	NM_002159	HTN1	histatin 1
chr5_+_71403040	1.979	NM_005909	MAP1B	microtubule-associated protein 1B
chr5_+_71502700	1.940		MAP1B	microtubule-associated protein 1B
chr1_+_78470593	1.912	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_+_110407389	1.884	NM_033035	TSLP	thymic stromal lymphopoietin
chr3_-_112358510	1.853		CCDC80	coiled-coil domain containing 80
chr1_+_115572414	1.849	NM_000549	TSHB	thyroid stimulating hormone, beta
chr5_-_168271852	1.641
chr2_-_200325200	1.634		SATB2	SATB homeobox 2
chr20_-_34025955	1.625	NM_000557	GDF5	growth differentiation factor 5
chr5_+_95066628	1.621	NM_014899	RHOBTB3	Rho-related BTB domain containing 3
chr3_-_112358758	1.607		CCDC80	coiled-coil domain containing 80
chr11_+_5710816	1.588	NM_001199573 NM_006074	TRIM22	tripartite motif containing 22
chr11_+_5710926	1.553		TRIM22	tripartite motif containing 22
chr2_-_200329810	1.506	NM_001172517	SATB2	SATB homeobox 2
chr5_+_140529619	1.474	NM_018939	PCDHB6	protocadherin beta 6
chr2_+_200323088	1.446
chr8_+_77593506	1.439	NM_024721	ZFHX4	zinc finger homeobox 4
chr9_+_120466607	1.413		TLR4	toll-like receptor 4
chr16_+_53133063	1.413		CHD9	chromodomain helicase DNA binding protein 9
chr3_-_112359277	1.401		CCDC80	coiled-coil domain containing 80
chr5_+_139505519	1.395	NM_001007189	IGIP	IgA-inducing protein homolog (Bos taurus)
chr3_-_195310770	1.361		APOD	apolipoprotein D
chr3_+_69812620	1.332	NM_001184967	MITF	microphthalmia-associated transcription factor
chr2_+_210444364	1.327	NM_002374 NM_031845 NM_031847	MAP2	microtubule-associated protein 2
chr3_-_112359251	1.323		CCDC80	coiled-coil domain containing 80
chr1_+_79086087	1.322	NM_006820	IFI44L	interferon-induced protein 44-like
chr15_+_93443559	1.319		CHD2	chromodomain helicase DNA binding protein 2
chr8_+_17433941	1.311	NM_006207	PDGFRL	platelet-derived growth factor receptor-like
chr2_+_152214105	1.311	NM_007115	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr8_-_108510094	1.302	NM_001146 NM_001199859	ANGPT1	angiopoietin 1
chr5_+_59784004	1.295		PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr5_+_92918924	1.279	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr11_-_27742224	1.241	NM_001143805 NM_001143806 NM_170732	BDNF	brain-derived neurotrophic factor
chr1_+_155853546	1.241		SYT11	synaptotagmin XI
chr2_+_189839078	1.234	NM_000090	COL3A1	collagen, type III, alpha 1
chr4_-_70626429	1.215	NM_014465	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr14_+_74035762	1.210	NM_006821	ACOT2	acyl-CoA thioesterase 2
chr5_+_140792507	1.190	NM_018913 NM_032090	PCDHGA10	protocadherin gamma subfamily A, 10
chr8_+_77593522	1.175		ZFHX4	zinc finger homeobox 4
chr9_-_95244750	1.172	NM_001193335 NM_017680	ASPN	asporin
chr1_+_74701070	1.156	NM_015978	TNNI3K	TNNI3 interacting kinase
chr10_-_50732142	1.120	NM_170753	PGBD3	piggyBac transposable element derived 3
chr8_+_70378858	1.114	NM_001128204 NM_015170	SULF1	sulfatase 1
chr8_+_17396285	1.084	NM_001164771 NM_003046	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr9_+_120466625	1.084		TLR4	toll-like receptor 4
chr5_+_141346401	1.074	NM_001201365 NM_183399	RNF14	ring finger protein 14
chr9_-_95244634	1.071		ASPN	asporin
chr2_+_189839113	1.058		COL3A1	collagen, type III, alpha 1
chr2_-_45236521	1.057	NM_016932	SIX2	SIX homeobox 2
chr10_+_124320180	1.049	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr17_-_67240955	1.026	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr9_-_14086901	1.020		NFIB	nuclear factor I/B
chr6_-_117747017	1.017	NM_002944	ROS1	c-ros oncogene 1 , receptor tyrosine kinase
chr5_-_124080773	0.991	NM_020747	ZNF608	zinc finger protein 608
chr1_-_232651227	0.985	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr2_-_145277568	0.977		ZEB2	zinc finger E-box binding homeobox 2
chr16_+_86612114	0.977	NM_005250	FOXL1	forkhead box L1
chr16_+_15596122	0.958	NM_001142469	C16orf45	chromosome 16 open reading frame 45
chr2_-_87248942	0.948	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr5_-_95158465	0.944	NM_001118890 NM_001243658 NM_001243659 NM_002064	GLRX	glutaredoxin (thioltransferase)
chr3_-_114478117	0.936	NM_001164344 NM_001164345	ZBTB20	zinc finger and BTB domain containing 20
chr11_-_27722599	0.935	NM_001143808 NM_001143809 NM_001143810 NM_001143811	BDNF	brain-derived neurotrophic factor
chr2_-_192711923	0.930	NM_004657	SDPR	serum deprivation response
chr5_+_67586466	0.923	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_+_120973374	0.917	NM_005422	TECTA	tectorin alpha
chr5_-_111091947	0.916	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr5_+_140771482	0.915	NM_014004 NM_032088	PCDHGA8	protocadherin gamma subfamily A, 8
chr10_+_70847817	0.915	NM_002727	SRGN	serglycin
chr2_-_200322699	0.905	NM_001172509	SATB2	SATB homeobox 2
chr7_-_14025826	0.894	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chr6_+_136172802	0.893	NM_018945	PDE7B	phosphodiesterase 7B
chr1_+_61869699	0.871		NFIA	nuclear factor I/A
chr10_+_70847857	0.837		SRGN	serglycin
chr14_-_92413738	0.832		FBLN5	fibulin 5
chr5_+_140718353	0.831	NM_018915 NM_032009	PCDHGA2	protocadherin gamma subfamily A, 2
chr5_-_95158365	0.829		GLRX	glutaredoxin (thioltransferase)
chr3_+_69985750	0.827	NM_000248 NM_001184968 NM_198158 NM_198178	MITF	microphthalmia-associated transcription factor
chrX_+_56755666	0.827		LOC550643	uncharacterized LOC550643
chr9_-_123812535	0.810	NM_001735	C5	complement component 5
chr6_-_46293628	0.808	NM_005822	RCAN2	regulator of calcineurin 2
chr2_-_175462428	0.804		WIPF1	WAS/WASL interacting protein family, member 1
chr10_-_70066594	0.796		PBLD	phenazine biosynthesis-like protein domain containing
chr6_+_155538096	0.766	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr7_-_50772997	0.766	NM_001001550	GRB10	growth factor receptor-bound protein 10
chr20_+_5987897	0.747	NM_001127458	CRLS1	cardiolipin synthase 1
chr9_+_2015218	0.747	NM_003070 NM_139045	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_55095263	0.734	NM_006206	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide
chr11_+_65266980	0.734
chr9_+_97521930	0.734	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr17_-_53800074	0.727	NM_018286	TMEM100	transmembrane protein 100
chr14_-_90085325	0.725	NM_001085471	FOXN3	forkhead box N3
chr2_-_224467049	0.721		SCG2	secretogranin II
chr16_+_69680959	0.719		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_67138013	0.715	NM_080284	ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6
chr12_+_21679190	0.711	NM_030572	C12orf39	chromosome 12 open reading frame 39
chr2_-_192711651	0.710		SDPR	serum deprivation response
chr17_-_66951381	0.710	NM_007168	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr6_-_46293404	0.710		RCAN2	regulator of calcineurin 2
chr1_+_145524989	0.699	NM_003637	ITGA10	integrin, alpha 10
chr5_+_140602914	0.697	NM_018934	PCDHB14	protocadherin beta 14
chr6_+_132873829	0.696	NM_053278	TAAR8	trace amine associated receptor 8
chr2_+_226265601	0.690	NM_020864	NYAP2	neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chrX_+_7137471	0.688	NM_000351	STS	steroid sulfatase (microsomal), isozyme S
chr11_-_62911692	0.684	NM_001136506	SLC22A24	solute carrier family 22, member 24
chr20_+_33134691	0.684	NM_181509	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha
chr2_-_224467095	0.679		SCG2	secretogranin II
chr11_-_118900078	0.678	NM_001164280	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr5_+_81601165	0.675	NM_001017971	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like
chrX_-_135863104	0.672		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_10605928	0.667	NM_002259 NM_007328	KLRC1	killer cell lectin-like receptor subfamily C, member 1
chr11_-_27723061	0.662	NM_170733	BDNF	brain-derived neurotrophic factor
chr5_+_140753480	0.654	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr19_-_9092017	0.653	NM_024690	MUC16	mucin 16, cell surface associated
chr2_+_88047603	0.649	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr2_-_224467142	0.647	NM_003469	SCG2	secretogranin II
chr10_-_69752385	0.643		HERC4	hect domain and RLD 4
chr16_-_4896197	0.643		GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr11_+_65271145	0.643
chr5_+_115898218	0.636
chr11_+_131240370	0.634	NM_001048209	NTM	neurotrimin
chr19_+_9486991	0.630	NM_001172651	ZNF177	zinc finger protein 177
chr17_-_39623476	0.628	NM_002278	KRT32	keratin 32
chr1_+_168250277	0.621	NM_005149	TBX19	T-box 19
chrX_-_135863033	0.620		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr16_+_69726751	0.619		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr19_-_48752921	0.618	NM_001184901 NM_001184903 NM_014959	CARD8	caspase recruitment domain family, member 8
chr17_-_39191100	0.603	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr17_-_55980749	0.597	NM_017949	CUEDC1	CUE domain containing 1
chr17_-_39183453	0.596	NM_031957	KRTAP1-5	keratin associated protein 1-5
chr8_-_82395401	0.588	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr3_-_167191808	0.587	NM_006217	SERPINI2	serpin peptidase inhibitor, clade I (pancpin), member 2
chr5_-_160112266	0.585		ATP10B	ATPase, class V, type 10B
chr14_+_100563817	0.578		EVL	Enah/Vasp-like
chr7_-_14029641	0.572	NM_001163147 NM_004956	ETV1	ets variant 1
chr4_+_41614725	0.567		LIMCH1	LIM and calponin homology domains 1
chr5_-_59783885	0.566	NM_001165899	PDE4D	phosphodiesterase 4D, cAMP-specific
chr3_-_112359547	0.564		CCDC80	coiled-coil domain containing 80
chr5_+_67588395	0.559	NM_001242466	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_+_79115476	0.554	NM_006417	IFI44	interferon-induced protein 44
chr12_-_47219734	0.550	NM_001143824 NM_018018	SLC38A4	solute carrier family 38, member 4
chr15_+_93443418	0.550	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr13_+_24144402	0.546	NM_001204459 NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr5_+_140624916	0.545		PCDHB15	protocadherin beta 15
chr17_+_41158741	0.544	NM_005533	IFI35	interferon-induced protein 35
chr2_-_211018294	0.541		C2orf67	chromosome 2 open reading frame 67
chr5_+_140810181	0.533		PCDHGA12	protocadherin gamma subfamily A, 12
chr1_+_207277577	0.532	NM_000715	C4BPA	complement component 4 binding protein, alpha
chr1_-_54199876	0.530	NM_147193	GLIS1	GLIS family zinc finger 1
chr2_-_188419049	0.529		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr5_+_304290	0.525	NM_001242412 NM_020731	AHRR	aryl-hydrocarbon receptor repressor
chrX_+_103031433	0.524	NM_001128834	PLP1	proteolipid protein 1
chr4_+_160188997	0.520	NM_014247	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2
chr4_-_138453628	0.518	NM_019035	PCDH18	protocadherin 18
chr5_+_147795459	0.515		FBXO38	F-box protein 38
chr3_-_71542628	0.513		FOXP1	forkhead box P1
chr5_-_75919051	0.512	NM_004101	F2RL2	coagulation factor II (thrombin) receptor-like 2
chr5_-_159827042	0.511	NM_022090	C5orf54	chromosome 5 open reading frame 54
chr5_+_126859157	0.511		PRRC1	proline-rich coiled-coil 1
chr5_-_41510627	0.507	NM_001005473	PLCXD3	phosphatidylinositol-specific phospholipase C, X domain containing 3
chr14_-_92198383	0.507	NM_024764	CATSPERB	cation channel, sperm-associated, beta
chr2_-_55845985	0.506		SMEK2	SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr5_-_39394423	0.496		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_-_29055048	0.494	NM_001005226	OR2B3	olfactory receptor, family 2, subfamily B, member 3
chr1_+_84630014	0.493	NM_001242857 NM_001242858 NM_001242859	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr5_+_140810126	0.492	NM_003735 NM_032094	PCDHGA12	protocadherin gamma subfamily A, 12
chr6_+_144612872	0.490	NM_007124	UTRN	utrophin
chr12_-_53074172	0.489	NM_006121	KRT1	keratin 1
chr9_+_118916069	0.489	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr22_+_22735202	0.488
chr15_-_37391893	0.486		MEIS2	Meis homeobox 2
chr9_-_104357202	0.484	NM_147180	PPP3R2	protein phosphatase 3, regulatory subunit B, beta
chr14_+_51955854	0.482	NM_001042481	FRMD6	FERM domain containing 6
chr3_-_18480203	0.477	NM_001131010	SATB1	SATB homeobox 1
chr12_+_60083125	0.477	NM_004731	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr7_-_141957846	0.475	NM_001001317	PRSS58	protease, serine, 58
chr13_-_103054027	0.475	NM_175929	FGF14	fibroblast growth factor 14
chr6_-_132272311	0.471	NM_001901	CTGF	connective tissue growth factor
chr10_-_92681025	0.468	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr14_+_52327021	0.468	NM_001243773 NM_001243774 NM_053064	GNG2	guanine nucleotide binding protein (G protein), gamma 2
chr14_+_55168831	0.466		SAMD4A	sterile alpha motif domain containing 4A
chr8_-_72268720	0.465	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr11_+_133938819	0.462	NM_001205329 NM_032801	JAM3	junctional adhesion molecule 3
chr6_+_46761093	0.460	NM_005588	MEP1A	meprin A, alpha (PABA peptide hydrolase)
chr1_+_183774214	0.455		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr2_-_190044330	0.452	NM_000393	COL5A2	collagen, type V, alpha 2
chr2_+_169757749	0.448	NM_001081686 NM_021176	G6PC2	glucose-6-phosphatase, catalytic, 2
chr6_-_41703938	0.448	NM_001167827	TFEB	transcription factor EB
chr1_+_162467622	0.447		UHMK1	U2AF homology motif (UHM) kinase 1
chr1_-_183622447	0.443	NM_203454	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chrX_+_118714297	0.443	NM_181777	UBE2A	ubiquitin-conjugating enzyme E2A

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.37	4.46e-03	GO:0006355	regulation of transcription, DNA-dependent
1.34	6.50e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.34	6.85e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.68	8.11e-03	GO:0007156	homophilic cell adhesion
1.32	1.19e-02	GO:0010468	regulation of gene expression
1.34	1.73e-02	GO:0051252	regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.37	1.04e-03	GO:0005576	extracellular region
1.47	1.71e-02	GO:0044421	extracellular region part

Nothing significant found in function category.