Motif ID: AGCUUAU

Z-value: 0.487


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
hsa-miR-21 MIMAT0000076
hsa-miR-590-5p MIMAT0003258



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_18480203 0.266 NM_001131010
SATB1
SATB homeobox 1
chr3_-_18466759 0.265 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr1_+_203274646 0.198 NM_006763
BTG2
BTG family, member 2
chr4_+_86699846 0.154 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr4_+_86396251 0.152 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr4_+_86851425 0.147 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr10_+_112631552 0.142 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr8_-_9009050 0.109 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr8_-_9008138 0.097 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr16_+_4382224 0.096 NM_032575
GLIS2
GLIS family zinc finger 2
chr8_+_98881277 0.093 NM_002380
NM_030583
MATN2

matrilin 2

chr9_-_95244750 0.092 NM_001193335
NM_017680
ASPN

asporin

chr10_+_72163860 0.088 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr22_+_46546498 0.085 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr3_-_24536176 0.084 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr9_-_98270830 0.076 NM_000264
PTCH1
patched 1
chr8_-_22550708 0.073 NM_004430
EGR3
early growth response 3
chr8_-_22549901 0.070 NM_001199880
EGR3
early growth response 3
chr17_-_32690180 0.068 NM_002981
CCL1
chemokine (C-C motif) ligand 1
chr2_-_55459698 0.068 NM_001135598
C2orf63
chromosome 2 open reading frame 63
chr8_-_22550057 0.065 NM_001199881
EGR3
early growth response 3
chr17_+_17942584 0.064 NM_024052
C17orf39
chromosome 17 open reading frame 39
chr2_-_55459406 0.063 NM_152385
C2orf63
chromosome 2 open reading frame 63
chr9_-_98269480 0.063 NM_001083607
PTCH1
patched 1
chr8_+_75736771 0.062 NM_015886
PI15
peptidase inhibitor 15
chr9_-_98270321 0.062 NM_001083604
NM_001083605
PTCH1

patched 1

chr10_+_124134093 0.060 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr8_-_97247757 0.060 NM_001199975
NM_006294
UQCRB

ubiquinol-cytochrome c reductase binding protein

chr8_-_57123858 0.056 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr6_-_109330190 0.055 NM_001199934
SESN1
sestrin 1
chr10_+_124151818 0.054 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr7_+_20370724 0.053 NM_002214
ITGB8
integrin, beta 8
chr1_+_218518675 0.052 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr15_-_38856830 0.052 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr12_+_12764755 0.050 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr9_+_36036900 0.049 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_109415514 0.048 NM_014454
SESN1
sestrin 1
chr10_+_124145584 0.047 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr9_-_98269686 0.047 NM_001083606
PTCH1
patched 1
chr6_-_109330752 0.047 NM_001199933
SESN1
sestrin 1
chr7_-_139876718 0.045 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr4_-_89744154 0.045 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr11_-_44331612 0.043 NM_021926
ALX4
ALX homeobox 4
chr12_-_10324675 0.043 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr15_+_66161769 0.042 NM_001206836
NM_004663
RAB11A

RAB11A, member RAS oncogene family

chr16_-_20911560 0.040 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr5_+_67584251 0.039 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_19282773 0.039 NM_001136265
IFFO2
intermediate filament family orphan 2
chr4_+_124320664 0.039 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_-_64371444 0.039 NM_020651
PELI1
pellino homolog 1 (Drosophila)
chr12_+_53845884 0.039 NM_001098620
NM_001128911
NM_001128912
NM_001128913
NM_001128914
NM_005016
NM_031989
PCBP2






poly(rC) binding protein 2






chr1_-_36851484 0.036 NM_032017
STK40
serine/threonine kinase 40
chr5_+_67511578 0.036 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_124317884 0.036 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr18_-_46477080 0.035 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr2_+_86947387 0.033 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_166428845 0.032 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr4_-_140060601 0.031 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr8_-_11058847 0.031 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr16_-_4588379 0.031 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr16_-_4588738 0.030 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr5_+_67586466 0.030 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_125695787 0.029 NM_001146319
GRAMD3
GRAM domain containing 3
chr16_-_4292052 0.029 NM_001098814
SRL
sarcalumenin
chr4_-_87028805 0.027 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr4_-_87374282 0.027 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr9_-_123476578 0.026 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr5_+_125758818 0.025 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr4_+_144257982 0.025 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr14_-_70655589 0.024 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr2_+_166326156 0.024 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr5_+_67588395 0.024 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_87281374 0.023 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr10_+_70320044 0.023 NM_030625
TET1
tet methylcytosine dioxygenase 1
chr11_-_73472057 0.022 NM_001243718
NM_002869
NM_198896
RAB6A


RAB6A, member RAS oncogene family


chr5_+_125800786 0.022 NM_001146322
GRAMD3
GRAM domain containing 3
chr17_-_40540491 0.022 NM_003150
NM_139276
STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

chr7_+_8008416 0.022 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr15_+_59063389 0.022 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chrX_-_131623994 0.021 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr6_+_148663728 0.021 NM_015278
SASH1
SAM and SH3 domain containing 1
chr3_+_159706622 0.021 NM_000882
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr4_+_153864134 0.021 NM_033393
FHDC1
FH2 domain containing 1
chr9_-_98279246 0.020 NM_001083602
NM_001083603
PTCH1

patched 1

chr3_+_29322802 0.020 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr17_+_61627818 0.019 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr20_+_56884749 0.019 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr1_+_61547625 0.019 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr18_-_46475702 0.019 NM_001190822
SMAD7
SMAD family member 7
chr6_-_134373618 0.019 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr12_+_27397077 0.018 NM_015000
STK38L
serine/threonine kinase 38 like
chr17_+_38278789 0.018 NM_001012241
MSL1
male-specific lethal 1 homolog (Drosophila)
chr4_-_89978117 0.018 NM_014883
FAM13A
family with sequence similarity 13, member A
chr14_-_70546863 0.018 NM_182936
NM_001130417
SLC8A3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr1_+_36273786 0.018 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr16_+_69599868 0.018 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr2_+_20646831 0.018 NM_004040
RHOB
ras homolog gene family, member B
chr11_+_64889699 0.017 NM_004927
MRPL49
mitochondrial ribosomal protein L49
chr7_+_114055048 0.017 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr5_-_88179278 0.017 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr3_+_186648273 0.017 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr11_+_101983170 0.017 NM_001195045
YAP1
Yes-associated protein 1
chr3_+_186739643 0.017 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr11_-_63536112 0.017 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr5_+_179921371 0.016 NM_015455
CNOT6
CCR4-NOT transcription complex, subunit 6
chr1_+_224301790 0.016 NM_001136115
NM_015176
FBXO28

F-box protein 28

chr13_-_36920603 0.015 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr3_+_10183318 0.015 NM_000551
NM_198156
VHL

von Hippel-Lindau tumor suppressor

chr11_+_101980736 0.015 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr2_-_172967234 0.015 NM_004405
DLX2
distal-less homeobox 2
chr13_-_36920777 0.015 NM_001142295
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr2_+_65283485 0.015 NM_015147
CEP68
centrosomal protein 68kDa
chr4_-_103790002 0.015 NM_181893
NM_181890
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr15_-_42840992 0.014 NM_153260
LRRC57
leucine rich repeat containing 57
chr9_-_34590137 0.014 NM_001207011
CNTFR
ciliary neurotrophic factor receptor
chrX_-_80065182 0.014 NM_153252
BRWD3
bromodomain and WD repeat domain containing 3
chr9_-_34589679 0.014 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr1_-_47134039 0.014 NM_001042546
NM_022745
ATPAF1

ATP synthase mitochondrial F1 complex assembly factor 1

chr5_-_88199868 0.013 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr9_+_115142188 0.013 NM_001195822
NM_032303
HSDL2

hydroxysteroid dehydrogenase like 2

chr9_-_16870719 0.013 NM_017637
BNC2
basonuclin 2
chr8_-_75233461 0.012 NM_020647
JPH1
junctophilin 1
chr1_+_178694273 0.012 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr9_+_133971862 0.012 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr5_+_31799030 0.012 NM_178140
PDZD2
PDZ domain containing 2
chr18_-_33647336 0.012 NM_018170
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr22_+_21213248 0.012 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr7_+_138916230 0.011 NM_173569
UBN2
ubinuclein 2
chr11_-_16430425 0.011 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr17_+_59477169 0.011 NM_005994
TBX2
T-box 2
chr1_+_61542928 0.011 NM_001145511
NFIA
nuclear factor I/A
chr10_-_94003002 0.011 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr1_-_68299047 0.011 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr14_+_33408458 0.011 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr7_+_28338939 0.010 NM_182899
CREB5
cAMP responsive element binding protein 5
chr7_+_28452143 0.010 NM_182898
CREB5
cAMP responsive element binding protein 5
chr8_+_87354958 0.010 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr12_+_27175482 0.010 NM_004264
MED21
mediator complex subunit 21
chr22_+_33196801 0.010 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr10_-_94050799 0.009 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr3_+_181429711 0.009 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr15_-_33360084 0.009 NM_001103184
FMN1
formin 1
chr13_-_41706587 0.009 NM_152903
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr11_-_128894008 0.009 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chrX_-_131547536 0.009 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr11_+_32851469 0.009 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chrX_-_18372777 0.009 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr5_-_141704575 0.009 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr11_-_129062092 0.009 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chrX_-_131573638 0.009 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr12_+_48499655 0.009 NM_001166686
PFKM
phosphofructokinase, muscle
chrX_-_20284708 0.008 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_+_88188261 0.008 NM_018293
ZNF654
zinc finger protein 654
chr21_-_39870303 0.008 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr6_+_119215240 0.008 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr8_-_101571870 0.008 NM_198401
GAPDHP62
ANKRD46
glyceraldehyde 3 phosphate dehydrogenase pseudogene 62
ankyrin repeat domain 46
chr5_-_160975124 0.008 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr4_-_103748966 0.007 NM_003340
NM_181886
NM_181888
NM_181889
UBE2D3



ubiquitin-conjugating enzyme E2D 3



chr18_-_46469118 0.007 NM_001190823
SMAD7
SMAD family member 7
chr2_+_66662516 0.007 NM_002398
MEIS1
Meis homeobox 1
chr11_-_16497917 0.007 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr20_+_278200 0.007 NM_033089
ZCCHC3
zinc finger, CCHC domain containing 3
chr3_+_98451537 0.007 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_+_36562089 0.007 NM_003017
SRSF3
serine/arginine-rich splicing factor 3
chr1_+_33004771 0.007 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr13_-_36944289 0.007 NM_001142294
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr1_-_196577438 0.007 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr5_+_139493689 0.007 NM_005859
PURA
purine-rich element binding protein A
chr7_+_101459092 0.007 NM_001202543
NM_001202544
NM_001202545
NM_001913
NM_181500
NM_001202546
CUX1





cut-like homeobox 1





chr12_-_121342050 0.006 NM_139015
SPPL3
signal peptide peptidase-like 3
chr1_-_151966713 0.006 NM_002966
S100A10
S100 calcium binding protein A10
chr7_+_28475233 0.006 NM_004904
CREB5
cAMP responsive element binding protein 5
chr4_-_103748254 0.006 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_-_111563278 0.006 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr2_+_70314560 0.005 NM_006196
PCBP1
poly(rC) binding protein 1
chrX_-_54384436 0.005 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr4_-_103748649 0.005 NM_181887
NM_181891
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr19_-_58662144 0.005 NM_024620
ZNF329
zinc finger protein 329
chr2_+_130737234 0.005 NM_032144
RAB6C
RAB6C, member RAS oncogene family
chr22_+_39101806 0.005 NM_004286
GTPBP1
GTP binding protein 1
chrX_+_72782961 0.004 NM_001039840
CHIC1
cysteine-rich hydrophobic domain 1
chr4_-_129209983 0.004 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr2_-_201936389 0.004 NM_173822
FAM126B
family with sequence similarity 126, member B
chrX_+_35937850 0.004 NM_152632
CXorf22
chromosome X open reading frame 22
chr2_-_132121730 0.004 NM_001077637
WTH3DI
RAB6C-like
chr13_+_20532906 0.004 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr1_-_26680620 0.004 NM_001039775
AIM1L
absent in melanoma 1-like
chr11_-_16424391 0.004 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr9_+_115513050 0.004 NM_001012994
SNX30
sorting nexin family member 30
chr1_+_213123853 0.004 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr17_-_40540359 0.003 NM_213662
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chrX_+_21392396 0.003 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr12_-_76425375 0.003 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr1_+_65210724 0.003 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr11_+_120207617 0.003 NM_001198665
NM_015313
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr12_-_70083055 0.002 NM_152439
BEST3
bestrophin 3
chr10_-_75910525 0.002 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chr1_+_53192021 0.002 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr1_-_153895450 0.002 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr12_+_50478942 0.002 NM_003076
NM_139071
SMARCD1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.59 9.61e-06 GO:0050794 regulation of cellular process
1.55 1.95e-05 GO:0050789 regulation of biological process
1.48 1.59e-04 GO:0065007 biological regulation
3.46 1.13e-03 GO:0051254 positive regulation of RNA metabolic process
2.05 1.14e-03 GO:0010468 regulation of gene expression
3.43 1.32e-03 GO:0010628 positive regulation of gene expression
3.53 1.60e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.52 1.69e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.36 3.25e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.06 4.87e-03 GO:0051252 regulation of RNA metabolic process
1.94 5.25e-03 GO:0048518 positive regulation of biological process
2.91 5.60e-03 GO:0006351 transcription, DNA-dependent
3.11 5.79e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
3.23 5.89e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.81 6.06e-03 GO:0060255 regulation of macromolecule metabolic process
3.05 7.51e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.16 7.93e-03 GO:0009890 negative regulation of biosynthetic process
4.02 9.30e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.73 9.53e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.96 1.17e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.63 1.44e-02 GO:0044260 cellular macromolecule metabolic process
3.45 1.47e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.51 1.59e-02 GO:0010604 positive regulation of macromolecule metabolic process
3.26 1.63e-02 GO:0010629 negative regulation of gene expression
1.93 1.86e-02 GO:0010556 regulation of macromolecule biosynthetic process
3.38 1.89e-02 GO:0051253 negative regulation of RNA metabolic process
1.93 2.32e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.62 2.76e-02 GO:0032774 RNA biosynthetic process
2.70 2.77e-02 GO:0031324 negative regulation of cellular metabolic process
1.91 2.84e-02 GO:0048522 positive regulation of cellular process
1.98 2.90e-02 GO:0006355 regulation of transcription, DNA-dependent
2.67 3.25e-02 GO:0010605 negative regulation of macromolecule metabolic process
2.72 4.00e-02 GO:0009891 positive regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 8.92e-03 GO:0005634 nucleus
2.21 1.36e-02 GO:0005654 nucleoplasm
2.62 3.54e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.04 3.75e-05 GO:0001071 nucleic acid binding transcription factor activity
3.04 3.75e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
3.25 5.96e-04 GO:0043565 sequence-specific DNA binding
1.69 1.23e-02 GO:0003676 nucleic acid binding
1.20 1.83e-02 GO:0005488 binding