Motif ID: ATF4.p2

Z-value: 0.912


Transcription factors associated with ATF4.p2:

Gene SymbolEntrez IDGene Name
ATF4 468 activating transcription factor 4 (tax-responsive enhancer element B67)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF4chr22_+_399165630.422.9e-01Click!


Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_68086633 2.908 ARG2
arginase, type II
chr20_+_58179601 1.820 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr14_+_68086570 1.814 NM_001172
ARG2
arginase, type II
chr16_+_22825481 1.572 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr14_+_68086655 1.329 ARG2
arginase, type II
chr8_-_95274540 1.137 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr4_+_75310852 0.984 NM_001657
AREG
amphiregulin
chr1_+_156030965 0.964 NM_020387
RAB25
RAB25, member RAS oncogene family
chr1_+_2005083 0.876 NM_001033581
PRKCZ
protein kinase C, zeta
chr8_-_95274520 0.874 GEM
GTP binding protein overexpressed in skeletal muscle
chr6_+_139456240 0.795 NM_016217
HECA
headcase homolog (Drosophila)
chr12_-_31881949 0.790 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr8_-_66754276 0.781 PDE7A
phosphodiesterase 7A
chr12_-_123380628 0.735 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr8_+_82644663 0.712 NM_152284
CHMP4C
charged multivesicular body protein 4C
chr12_-_31882006 0.704 NM_001113402
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr4_+_85504056 0.696 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr8_+_61591239 0.675 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr1_+_44398991 0.673 NM_001136215
NM_057090
NM_057091
ARTN


artemin


chr10_+_134210691 0.628 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr12_-_123380682 0.608 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr14_+_96671015 0.598 NM_000623
BDKRB2
bradykinin receptor B2
chr7_+_86273219 0.590 NM_000840
GRM3
glutamate receptor, metabotropic 3
chrX_-_102565805 0.570 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr4_+_75480628 0.566 NM_001657
AREG
amphiregulin
chr1_+_26496382 0.563 NM_015871
ZNF593
zinc finger protein 593
chr6_+_28048481 0.555 NM_003447
ZNF165
zinc finger protein 165
chr8_+_61591358 0.554 CHD7
chromodomain helicase DNA binding protein 7
chr5_-_1882764 0.535 NM_016358
IRX4
iroquois homeobox 4
chr6_-_91006580 0.527 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr6_-_91006460 0.502 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr7_-_140624280 0.496 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr9_-_139948448 0.493 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr3_-_46735133 0.456 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr10_+_23983674 0.448 NM_001098500
KIAA1217
KIAA1217
chr20_+_44637539 0.446 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr12_-_12715244 0.434 NM_030640
DUSP16
dual specificity phosphatase 16
chr17_-_4643162 0.428 NM_001100812
NM_022059
CXCL16

chemokine (C-X-C motif) ligand 16

chr18_+_23806385 0.424 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr17_-_4642638 0.422 CXCL16
chemokine (C-X-C motif) ligand 16
chr2_-_220408264 0.419 NM_024536
CHPF
chondroitin polymerizing factor
chr19_+_18284578 0.417 NM_006332
IFI30
interferon, gamma-inducible protein 30
chr1_+_212782103 0.415 ATF3
activating transcription factor 3
chr1_+_26856252 0.414 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_+_112856756 0.414 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr11_-_77184549 0.408 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr8_-_66753968 0.402 NM_001242318
PDE7A
phosphodiesterase 7A
chr7_-_36406446 0.400 NM_001199707
NM_001199706
NM_015314
NM_001199708
KIAA0895



KIAA0895



chr1_+_26856259 0.398 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr11_+_62649160 0.395 SLC3A2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr19_+_18284631 0.393 IFI30
interferon, gamma-inducible protein 30
chr20_-_1294111 0.376 NM_015685
SDCBP2
syndecan binding protein (syntenin) 2
chr17_-_8151353 0.374 CTC1
CTS telomere maintenance complex component 1
chr11_-_119234628 0.373 USP2
ubiquitin specific peptidase 2
chr7_-_22396511 0.372 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr7_+_16793320 0.371 NM_014399
TSPAN13
tetraspanin 13
chr20_+_35201948 0.371 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr3_-_33759684 0.370 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr10_-_50970321 0.363 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr5_-_95297424 0.361 ELL2
elongation factor, RNA polymerase II, 2
chr16_+_81348583 0.358 GAN
gigaxonin
chr3_-_33759540 0.357 CLASP2
cytoplasmic linker associated protein 2
chr1_+_29562947 0.353 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr7_+_30174343 0.352 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr9_-_77643307 0.350 NM_152420
C9orf41
chromosome 9 open reading frame 41
chr16_+_81348564 0.346 NM_022041
GAN
gigaxonin
chr1_+_2005424 0.341 NM_001242874
PRKCZ
protein kinase C, zeta
chr8_+_98788014 0.340 LAPTM4B
lysosomal protein transmembrane 4 beta
chr1_+_55505207 0.340 PCSK9
proprotein convertase subtilisin/kexin type 9
chr1_+_60280462 0.339 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr14_-_95786095 0.336 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr21_-_43187197 0.332 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr16_+_22825806 0.330 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr9_+_131644368 0.326 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr7_+_5632435 0.326 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr21_-_43187265 0.317 RIPK4
receptor-interacting serine-threonine kinase 4
chr13_-_101327102 0.306 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr19_+_13056607 0.303 NM_005053
RAD23A
RAD23 homolog A (S. cerevisiae)
chr9_-_77643156 0.298 C9orf41
chromosome 9 open reading frame 41
chr5_-_175964223 0.297 NM_014901
RNF44
ring finger protein 44
chr19_+_1067536 0.296 HMHA1
histocompatibility (minor) HA-1
chr1_+_212781969 0.293 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr9_-_77643179 0.292 C9orf41
chromosome 9 open reading frame 41
chr7_+_44646180 0.290 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_20370324 0.288 ITGB8
integrin, beta 8
chr5_-_95297597 0.287 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr19_+_45504686 0.287 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr16_+_2022039 0.286 TBL3
transducin (beta)-like 3
chr18_+_596997 0.285 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr16_-_4588738 0.282 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr15_+_81293286 0.281 NM_022566
MESDC1
mesoderm development candidate 1
chr12_+_4382882 0.280 NM_001759
CCND2
cyclin D2
chr5_-_16617085 0.279 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr19_-_291335 0.279 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr17_+_41476351 0.275 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr7_-_994008 0.274 ADAP1
ArfGAP with dual PH domains 1
chr7_-_45151272 0.274 TBRG4
transforming growth factor beta regulator 4
chr6_+_37225506 0.272 NM_017772
TBC1D22B
TBC1 domain family, member 22B
chr16_-_3767449 0.272 NM_016292
TRAP1
TNF receptor-associated protein 1
chr19_-_42721802 0.272 NM_133328
DEDD2
death effector domain containing 2
chr17_-_7165788 0.269 CLDN7
claudin 7
chr1_+_151253977 0.265 ZNF687
zinc finger protein 687
chr9_-_140353785 0.263 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr9_+_131644427 0.262 LRRC8A
leucine rich repeat containing 8 family, member A
chr21_-_44299660 0.262 NM_018669
NM_033661
WDR4

WD repeat domain 4

chr3_-_33759743 0.261 CLASP2
cytoplasmic linker associated protein 2
chr12_-_64616032 0.258 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr6_-_34664517 0.256 C6orf106
chromosome 6 open reading frame 106
chr1_+_117452359 0.256 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr4_-_100485173 0.255 NM_001134665
NM_001134666
RG9MTD2

RNA (guanine-9-) methyltransferase domain containing 2

chr5_-_175843531 0.255 NM_001834
NM_007097
CLTB

clathrin, light chain B

chr2_+_97426571 0.253 NM_020184
CNNM4
cyclin M4
chr11_+_66188474 0.252 NM_178864
NPAS4
neuronal PAS domain protein 4
chr15_+_74908195 0.252 CLK3
CDC-like kinase 3
chr21_-_44299605 0.251 WDR4
WD repeat domain 4
chr13_-_101327027 0.247 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr9_-_99801365 0.245 NM_001333
CTSL2
cathepsin L2
chr12_+_97301000 0.243 NM_001135176
NM_001135177
NM_152905
NEDD1


neural precursor cell expressed, developmentally down-regulated 1


chr17_+_18086813 0.242 NM_017758
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr19_+_35491225 0.241 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr16_-_4588379 0.238 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr5_-_175843360 0.236 CLTB
clathrin, light chain B
chr11_-_78285869 0.234 NM_001243251
NM_024678
NARS2

asparaginyl-tRNA synthetase 2, mitochondrial (putative)

chr10_-_105614952 0.234 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr19_+_13056671 0.232 RAD23A
RAD23 homolog A (S. cerevisiae)
chr4_+_142142044 0.231 NM_014487
ZNF330
zinc finger protein 330
chr1_-_52870058 0.231 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr4_-_48908744 0.231 NM_001014446
NM_152398
OCIAD2

OCIA domain containing 2

chr1_+_65613771 0.229 NM_013410
AK4
adenylate kinase 4
chr16_+_68057144 0.227 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr19_-_50979461 0.224 FAM71E1
family with sequence similarity 71, member E1
chr5_+_112849352 0.223 NM_022828
YTHDC2
YTH domain containing 2
chr2_-_32236104 0.221 MEMO1
mediator of cell motility 1
chr9_-_140353748 0.220 NELF
nasal embryonic LHRH factor
chr19_+_18723666 0.220 NM_012109
TMEM59L
transmembrane protein 59-like
chr15_-_72612247 0.219 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr7_+_66767642 0.219 STAG3L4
stromal antigen 3-like 4
chr22_-_44258210 0.218 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr22_+_24236569 0.217 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr19_+_34895268 0.215 NM_032346
PDCD2L
programmed cell death 2-like
chr15_-_72612497 0.215 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr8_-_104427319 0.214 SLC25A32
solute carrier family 25, member 32
chr22_+_24236556 0.214 NM_002415
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr2_+_106361404 0.214 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr22_+_24236586 0.214 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr16_+_57662301 0.214 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr10_-_99094427 0.213 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr22_+_24236575 0.212


chr17_+_29421941 0.212 NM_000267
NM_001042492
NM_001128147
NF1


neurofibromin 1


chr7_-_105925329 0.211 NAMPT
nicotinamide phosphoribosyltransferase
chr19_+_39897457 0.210 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr9_-_135996287 0.210 NM_006266
RALGDS
ral guanine nucleotide dissociation stimulator
chr11_+_108535773 0.210 NM_004398
DDX10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr3_+_10068123 0.209 FANCD2
Fanconi anemia, complementation group D2
chr1_-_16482426 0.208 NM_004431
EPHA2
EPH receptor A2
chr19_+_35491329 0.208 GRAMD1A
GRAM domain containing 1A
chr11_-_2193015 0.208 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr20_+_361675 0.206 TRIB3
tribbles homolog 3 (Drosophila)
chr17_+_18087091 0.206 ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr17_+_55333843 0.206 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr3_+_150125983 0.205 TSC22D2
TSC22 domain family, member 2
chr6_+_26204779 0.204 NM_003545
HIST1H4E
histone cluster 1, H4e
chr11_+_67351276 0.203 GSTP1
glutathione S-transferase pi 1
chr8_+_26149043 0.202 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr8_-_104427268 0.201 SLC25A32
solute carrier family 25, member 32
chr22_+_24236595 0.201 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr1_+_55505148 0.200 NM_174936
PCSK9
proprotein convertase subtilisin/kexin type 9
chr12_+_112856535 0.200 NM_002834
PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr12_+_19592777 0.200 AEBP2
AE binding protein 2
chr19_-_47734215 0.199 NM_014417
BBC3
BCL2 binding component 3
chr8_+_26149004 0.199 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chrY_-_297689 0.198 NM_013239
PPP2R3B
protein phosphatase 2, regulatory subunit B'', beta
chr7_-_76256475 0.198 NM_012230
NM_152992
POMZP3

POM121 and ZP3 fusion

chr5_-_16509106 0.198 NM_019000
FAM134B
family with sequence similarity 134, member B
chr11_+_73087396 0.198 NM_152222
RELT
RELT tumor necrosis factor receptor
chr22_+_24236579 0.197 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr18_-_33647336 0.197 NM_018170
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr7_-_128045995 0.197 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr19_-_18314731 0.196 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr3_-_150480917 0.196 SIAH2
seven in absentia homolog 2 (Drosophila)
chr8_+_98787808 0.195 NM_018407
LAPTM4B
lysosomal protein transmembrane 4 beta
chr3_+_42190736 0.195 TRAK1
trafficking protein, kinesin binding 1
chr9_+_125027152 0.194 MRRF
mitochondrial ribosome recycling factor
chr12_+_112856701 0.194 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr19_+_13056656 0.194 RAD23A
RAD23 homolog A (S. cerevisiae)
chr2_+_74757243 0.194 HTRA2
HtrA serine peptidase 2
chr16_-_88772732 0.194 NM_001171815
RNF166
ring finger protein 166
chr7_+_5632453 0.193 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr16_+_68679198 0.193 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr20_+_56285213 0.193


chr4_-_100484824 0.193 NM_152292
RG9MTD2
RNA (guanine-9-) methyltransferase domain containing 2
chr3_+_128445026 0.193 RAB7A
RAB7A, member RAS oncogene family
chr10_+_103911932 0.192 NM_004741
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr1_+_40420802 0.190 MFSD2A
major facilitator superfamily domain containing 2A
chr1_-_161147209 0.188 B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr22_-_20104695 0.188 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr9_+_131644780 0.187 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr9_-_77643024 0.186 C9orf41
chromosome 9 open reading frame 41
chr6_+_30295007 0.185 NM_172016
TRIM39
tripartite motif containing 39
chr10_-_131762017 0.184 NM_001005463
EBF3
early B-cell factor 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.51 3.25e-15 GO:0044260 cellular macromolecule metabolic process
1.42 5.20e-12 GO:0043170 macromolecule metabolic process
1.34 5.26e-11 GO:0044237 cellular metabolic process
1.60 1.10e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 5.64e-10 GO:0044238 primary metabolic process
1.53 6.47e-10 GO:0034641 cellular nitrogen compound metabolic process
1.66 8.33e-10 GO:0090304 nucleic acid metabolic process
1.51 1.78e-09 GO:0006807 nitrogen compound metabolic process
1.71 4.75e-09 GO:0010467 gene expression
1.28 8.16e-09 GO:0008152 metabolic process
1.52 7.26e-07 GO:0044267 cellular protein metabolic process
1.61 6.24e-06 GO:0016070 RNA metabolic process
1.62 9.50e-06 GO:0034645 cellular macromolecule biosynthetic process
1.61 1.16e-05 GO:0009059 macromolecule biosynthetic process
1.14 2.33e-05 GO:0009987 cellular process
1.44 3.10e-04 GO:0044249 cellular biosynthetic process
1.38 5.04e-04 GO:0019538 protein metabolic process
1.53 1.44e-03 GO:0006996 organelle organization
1.39 3.84e-03 GO:0009058 biosynthetic process
1.37 4.33e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.66 5.75e-03 GO:0032774 RNA biosynthetic process
1.30 1.13e-02 GO:0071840 cellular component organization or biogenesis
2.19 1.50e-02 GO:0051325 interphase
2.18 1.63e-02 GO:0006412 translation
2.25 1.83e-02 GO:0034660 ncRNA metabolic process
1.69 1.87e-02 GO:0022402 cell cycle process
1.60 2.30e-02 GO:0007049 cell cycle
1.77 2.42e-02 GO:0006396 RNA processing
1.65 2.53e-02 GO:0006351 transcription, DNA-dependent
1.34 3.45e-02 GO:0071842 cellular component organization at cellular level
2.87 4.30e-02 GO:0050657 nucleic acid transport
2.87 4.30e-02 GO:0050658 RNA transport
2.87 4.30e-02 GO:0051236 establishment of RNA localization
1.72 4.82e-02 GO:0022403 cell cycle phase

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 1.82e-18 GO:0005622 intracellular
1.21 1.03e-17 GO:0044424 intracellular part
1.29 4.56e-17 GO:0043231 intracellular membrane-bounded organelle
1.29 6.25e-17 GO:0043227 membrane-bounded organelle
1.25 3.69e-16 GO:0043229 intracellular organelle
1.25 6.35e-16 GO:0043226 organelle
1.75 6.06e-14 GO:0044428 nuclear part
1.81 2.01e-13 GO:0031981 nuclear lumen
1.72 2.45e-13 GO:0070013 intracellular organelle lumen
1.38 7.40e-13 GO:0044422 organelle part
1.38 8.14e-13 GO:0044446 intracellular organelle part
1.69 8.25e-13 GO:0031974 membrane-enclosed lumen
1.69 1.08e-12 GO:0043233 organelle lumen
1.37 3.61e-12 GO:0005634 nucleus
1.26 8.76e-12 GO:0005737 cytoplasm
1.86 4.07e-10 GO:0005654 nucleoplasm
1.43 5.90e-06 GO:0043228 non-membrane-bounded organelle
1.43 5.90e-06 GO:0043232 intracellular non-membrane-bounded organelle
2.12 1.18e-05 GO:0005730 nucleolus
1.24 2.76e-05 GO:0044444 cytoplasmic part
1.97 1.35e-04 GO:0005694 chromosome
1.75 1.60e-03 GO:0044451 nucleoplasm part
1.29 1.78e-03 GO:0032991 macromolecular complex
1.89 6.04e-03 GO:0044427 chromosomal part
1.70 6.65e-03 GO:0031967 organelle envelope
1.38 6.97e-03 GO:0005829 cytosol
1.67 1.17e-02 GO:0031975 envelope
1.80 1.27e-02 GO:0030529 ribonucleoprotein complex
13.52 2.24e-02 GO:0005663 DNA replication factor C complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.34 2.88e-16 GO:0005515 protein binding
1.15 2.89e-09 GO:0005488 binding
1.78 1.48e-04 GO:0003723 RNA binding
1.34 2.37e-04 GO:0003676 nucleic acid binding
1.54 2.38e-04 GO:0005524 ATP binding
1.53 2.61e-04 GO:0030554 adenyl nucleotide binding
1.53 3.25e-04 GO:0032559 adenyl ribonucleotide binding
1.47 3.94e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.46 5.62e-04 GO:0017076 purine nucleotide binding
1.45 6.47e-04 GO:0032553 ribonucleotide binding
1.45 6.47e-04 GO:0032555 purine ribonucleotide binding
1.38 2.79e-03 GO:0000166 nucleotide binding
4.61 3.47e-03 GO:0004722 protein serine/threonine phosphatase activity
1.20 1.97e-02 GO:0003824 catalytic activity