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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ATF5_CREB3.p2

Z-value: 0.962

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_+_68086633	1.192		ARG2	arginase, type II
chr14_+_68086655	0.759		ARG2	arginase, type II
chr2_+_75061234	0.621		HK2	hexokinase 2
chr20_+_58179601	0.620	NM_080672	PHACTR3	phosphatase and actin regulator 3
chr1_+_156030965	0.601	NM_020387	RAB25	RAB25, member RAS oncogene family
chr4_+_75480628	0.580	NM_001657	AREG	amphiregulin
chr4_+_75310852	0.575	NM_001657	AREG	amphiregulin
chr14_+_68086570	0.555	NM_001172	ARG2	arginase, type II
chr2_-_60780767	0.538		BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr5_-_95297424	0.441		ELL2	elongation factor, RNA polymerase II, 2
chr12_-_31881949	0.403		AMN1	antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr22_-_44258210	0.390	NM_014351	SULT4A1	sulfotransferase family 4A, member 1
chr12_-_31882006	0.382	NM_001113402	AMN1	antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr2_-_60780404	0.372	NM_018014 NM_022893 NM_138559	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr8_-_95274520	0.369		GEM	GTP binding protein overexpressed in skeletal muscle
chr16_+_19078958	0.355		COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr12_-_132628841	0.340	NM_175066	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr8_-_66754276	0.335		PDE7A	phosphodiesterase 7A
chr5_-_95297597	0.324	NM_012081	ELL2	elongation factor, RNA polymerase II, 2
chr6_-_15248886	0.324
chr13_+_32889594	0.322	NM_000059	BRCA2	breast cancer 2, early onset
chr11_-_111749810	0.320		FDXACB1	ferredoxin-fold anticodon binding domain containing 1
chr4_+_85504056	0.317	NM_001263	CDS1	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr8_+_61591239	0.308	NM_017780	CHD7	chromodomain helicase DNA binding protein 7
chr20_+_21686515	0.304		PAX1	paired box 1
chr3_-_33759540	0.298		CLASP2	cytoplasmic linker associated protein 2
chr21_-_44299605	0.294		WDR4	WD repeat domain 4
chr9_-_130477918	0.291	NM_001002913	PTRH1	peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr21_-_44299660	0.291	NM_018669 NM_033661	WDR4	WD repeat domain 4
chr2_-_192015706	0.289		STAT4	signal transducer and activator of transcription 4
chr5_+_159343739	0.289	NM_000679	ADRA1B	adrenergic, alpha-1B-, receptor
chr1_-_32110464	0.286		PEF1	penta-EF-hand domain containing 1
chr18_+_23806385	0.284	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr2_-_38604380	0.284		ATL2	atlastin GTPase 2
chr8_-_95274540	0.281	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr11_-_77184549	0.278	NM_001128620 NM_002576	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr10_+_112257624	0.259	NM_004419	DUSP5	dual specificity phosphatase 5
chr11_+_65337923	0.257	NM_006396	SSSCA1	Sjogren syndrome/scleroderma autoantigen 1
chr2_+_207139413	0.257	NM_020923	ZDBF2	zinc finger, DBF-type containing 2
chr13_-_45563554	0.253	NM_012345	NUFIP1	nuclear fragile X mental retardation protein interacting protein 1
chr18_+_47088400	0.249	NM_006033	LIPG	lipase, endothelial
chr8_+_118532970	0.248		MED30	mediator complex subunit 30
chr3_-_33759684	0.244	NM_015097	CLASP2	cytoplasmic linker associated protein 2
chr2_-_192015733	0.244		STAT4	signal transducer and activator of transcription 4
chr7_+_5632435	0.243	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_-_713985	0.241		LOC100288069	general transcription factor IIi pseudogene
chr6_+_31430955	0.239		HCP5	HLA complex P5 (non-protein coding)
chr2_-_192015751	0.239		STAT4	signal transducer and activator of transcription 4
chr7_+_44646197	0.238		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr16_+_68057144	0.237	NM_017803	DUS2L	dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr7_+_44646189	0.237		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_44646168	0.235		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr8_+_118532953	0.234	NM_080651	MED30	mediator complex subunit 30
chr2_-_38604430	0.233	NM_001135673 NM_022374	ATL2	atlastin GTPase 2
chr2_+_118572283	0.231		DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr9_+_102584136	0.231	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr16_-_3930713	0.229		CREBBP	CREB binding protein
chr7_-_100808832	0.228	NM_003378	VGF	VGF nerve growth factor inducible
chr3_-_33759743	0.228		CLASP2	cytoplasmic linker associated protein 2
chr16_+_19079220	0.227	NM_001190983	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr5_-_64777703	0.227	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr12_-_124068864	0.226
chr7_+_44646180	0.226		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr9_+_125027152	0.226		MRRF	mitochondrial ribosome recycling factor
chr6_+_28048481	0.225	NM_003447	ZNF165	zinc finger protein 165
chr19_+_1753661	0.224	NM_001080488	ONECUT3	one cut homeobox 3
chr17_+_55333843	0.223	NM_138962	MSI2	musashi homolog 2 (Drosophila)
chr5_+_52776479	0.222		FST	follistatin
chr20_+_35201948	0.220	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr11_+_67195886	0.220	NM_003952	RPS6KB2	ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr16_+_19078916	0.220	NM_016138	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_185303961	0.217	NM_021627	SENP2	SUMO1/sentrin/SMT3 specific peptidase 2
chr7_+_97736118	0.216	NM_014916	LMTK2	lemur tyrosine kinase 2
chr5_+_52776408	0.216		FST	follistatin
chr2_+_118572254	0.212	NM_006773	DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr17_-_685385	0.210	NM_016080	GLOD4	glyoxalase domain containing 4
chr12_-_31477080	0.206		FAM60A	family with sequence similarity 60, member A
chr2_+_118572284	0.204		DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr1_-_209979388	0.202	NM_001206696 NM_006147	IRF6	interferon regulatory factor 6
chr17_+_1633754	0.202		WDR81	WD repeat domain 81
chr6_+_41888993	0.201		BYSL	bystin-like
chr4_-_113558120	0.197	NM_018392	C4orf21	chromosome 4 open reading frame 21
chr17_-_48474864	0.197		LRRC59	leucine rich repeat containing 59
chr6_+_41888964	0.197	NM_004053	BYSL	bystin-like
chr17_+_18087091	0.196		ALKBH5	alkB, alkylation repair homolog 5 (E. coli)
chr7_+_44646220	0.196		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr16_+_15068921	0.195		PDXDC1	pyridoxal-dependent decarboxylase domain containing 1
chr12_+_112856756	0.194		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chr11_-_65667809	0.193		FOSL1	FOS-like antigen 1
chr16_-_68057098	0.192		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr1_+_234349995	0.192		SLC35F3	solute carrier family 35, member F3
chr17_-_13505217	0.189	NM_006042	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr2_-_54198055	0.188
chr3_+_150125983	0.188		TSC22D2	TSC22 domain family, member 2
chr10_+_5406975	0.187	NM_053049	UCN3	urocortin 3 (stresscopin)
chr3_+_10068123	0.186		FANCD2	Fanconi anemia, complementation group D2
chr19_+_49375677	0.185		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr1_+_26496382	0.185	NM_015871	ZNF593	zinc finger protein 593
chr7_+_5632453	0.184		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr17_+_18086813	0.183	NM_017758	ALKBH5	alkB, alkylation repair homolog 5 (E. coli)
chr12_-_12715244	0.182	NM_030640	DUSP16	dual specificity phosphatase 16
chr5_+_72861567	0.180	NM_032175	UTP15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr19_+_4402658	0.180	NM_005483	CHAF1A	chromatin assembly factor 1, subunit A (p150)
chr16_-_3767449	0.180	NM_016292	TRAP1	TNF receptor-associated protein 1
chr6_+_41889191	0.180		BYSL	bystin-like
chr10_+_103911932	0.179	NM_004741	NOLC1	nucleolar and coiled-body phosphoprotein 1
chr19_+_49375679	0.179		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr12_-_14956315	0.179		WBP11	WW domain binding protein 11
chr13_-_95364248	0.178	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr1_+_2005083	0.177	NM_001033581	PRKCZ	protein kinase C, zeta
chr19_+_10362886	0.176		MRPL4	mitochondrial ribosomal protein L4
chr19_+_49375638	0.176	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr16_-_4588738	0.175	NM_001199055 NM_001199056 NM_013399	C16orf5	chromosome 16 open reading frame 5
chr12_-_31479120	0.175	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr19_-_815243	0.174		LPPR3	lipid phosphate phosphatase-related protein type 3
chr1_+_212782103	0.174		ATF3	activating transcription factor 3
chr12_-_31479038	0.173		FAM60A	family with sequence similarity 60, member A
chr12_-_31479084	0.173		FAM60A	family with sequence similarity 60, member A
chr11_-_65667860	0.172	NM_005438	FOSL1	FOS-like antigen 1
chr15_+_66679107	0.172	NM_002755	MAP2K1	mitogen-activated protein kinase kinase 1
chr22_+_32340435	0.171	NM_003405	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr9_-_77643307	0.171	NM_152420	C9orf41	chromosome 9 open reading frame 41
chr7_+_44646120	0.171	NM_001003941 NM_001165036 NM_002541	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_-_140624280	0.169	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr5_+_112849352	0.168	NM_022828	YTHDC2	YTH domain containing 2
chrX_+_24167728	0.168	NM_001178086 NM_001178095 NM_001178084 NM_001178085 NM_003410	ZFX	zinc finger protein, X-linked
chr6_+_26204779	0.166	NM_003545	HIST1H4E	histone cluster 1, H4e
chr1_-_16482426	0.163	NM_004431	EPHA2	EPH receptor A2
chr16_+_67694795	0.163	NM_001037281 NM_016948	PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)
chr6_+_30585485	0.162	NM_014046	MRPS18B	mitochondrial ribosomal protein S18B
chr8_-_131028833	0.162		FAM49B	family with sequence similarity 49, member B
chr8_+_38243958	0.162	NM_001199659 NM_144652	LETM2	leucine zipper-EF-hand containing transmembrane protein 2
chr6_-_34360310	0.161		NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3
chrX_+_24167861	0.161		ZFX	zinc finger protein, X-linked
chr22_-_26879761	0.161	NM_022081	HPS4	Hermansky-Pudlak syndrome 4
chr16_+_58283819	0.161	NM_001142302 NM_014157	CCDC113	coiled-coil domain containing 113
chr8_+_61591358	0.160		CHD7	chromodomain helicase DNA binding protein 7
chr6_-_136871542	0.160		MAP7	microtubule-associated protein 7
chr12_+_22778085	0.160		ETNK1	ethanolamine kinase 1
chr22_-_26879724	0.159		HPS4	Hermansky-Pudlak syndrome 4
chr11_-_119252267	0.159		USP2	ubiquitin specific peptidase 2
chr1_-_53704121	0.159	NM_002370	MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)
chr11_-_118927815	0.159		HYOU1	hypoxia up-regulated 1
chr2_-_217236666	0.158	NM_020814	MARCH4	membrane-associated ring finger (C3HC4) 4
chr12_-_14956408	0.158		WBP11	WW domain binding protein 11
chr6_+_26597131	0.157	NM_013375	ABT1	activator of basal transcription 1
chr12_+_4382882	0.156	NM_001759	CCND2	cyclin D2
chr1_-_156786500	0.156	NM_001161441 NM_001161442 NM_001161444 NM_003975	SH2D2A	SH2 domain containing 2A
chr3_+_44803280	0.156		KIF15	kinesin family member 15
chr17_-_41322211	0.155		BRCA1	breast cancer 1, early onset
chr16_-_68057120	0.155		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr17_+_48585912	0.155		MYCBPAP	MYCBP associated protein
chr6_+_126661221	0.154	NM_001012507	CENPW	centromere protein W
chr2_-_192015934	0.153	NM_003151	STAT4	signal transducer and activator of transcription 4
chr11_+_73087396	0.153	NM_152222	RELT	RELT tumor necrosis factor receptor
chr3_+_45017729	0.153	NM_015004	EXOSC7	exosome component 7
chr11_-_119234628	0.152		USP2	ubiquitin specific peptidase 2
chr11_-_65667858	0.152		FOSL1	FOS-like antigen 1
chr6_-_166401526	0.152		LINC00473	long intergenic non-protein coding RNA 473
chr7_-_45151272	0.151		TBRG4	transforming growth factor beta regulator 4
chr1_-_31769599	0.151	NM_004814	SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)
chr3_-_195808980	0.150		TFRC	transferrin receptor (p90, CD71)
chr19_+_7701976	0.150	NM_001127396 NM_006949	STXBP2	syntaxin binding protein 2
chr2_+_97001506	0.149		NCAPH	non-SMC condensin I complex, subunit H
chr3_+_45017749	0.148		EXOSC7	exosome component 7
chr19_+_7702020	0.147		STXBP2	syntaxin binding protein 2
chr13_+_48877950	0.147		RB1	retinoblastoma 1
chr6_-_166401403	0.146		LINC00473	long intergenic non-protein coding RNA 473
chr4_-_122744782	0.145		CCNA2	cyclin A2
chr22_+_32340592	0.145		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr1_-_202927269	0.144		ADIPOR1	adiponectin receptor 1
chr11_+_65292576	0.144		SCYL1	SCY1-like 1 (S. cerevisiae)
chr2_+_231577536	0.144	NM_016289	CAB39	calcium binding protein 39
chr1_-_202896315	0.143		KLHL12	kelch-like 12 (Drosophila)
chr12_-_6862131	0.143		MLF2	myeloid leukemia factor 2
chr2_-_165477818	0.143		GRB14	growth factor receptor-bound protein 14
chr1_+_84864214	0.142	NM_021233	DNASE2B	deoxyribonuclease II beta
chr9_-_77643156	0.140		C9orf41	chromosome 9 open reading frame 41
chr17_+_42385780	0.139	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr20_+_56285213	0.139
chr21_-_34915124	0.138	NM_001136005 NM_001136006	GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr3_+_44803208	0.138	NM_020242	KIF15	kinesin family member 15
chr19_+_7702010	0.137		STXBP2	syntaxin binding protein 2
chr1_-_175712669	0.137	NM_003285	TNR	tenascin R (restrictin, janusin)
chr4_+_84457256	0.137		AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr20_+_21686293	0.136	NM_006192	PAX1	paired box 1
chr4_-_122744978	0.136	NM_001237	CCNA2	cyclin A2
chr12_-_82752154	0.135	NM_014167	CCDC59	coiled-coil domain containing 59
chr1_-_202927439	0.135		ADIPOR1	adiponectin receptor 1
chr11_-_2193015	0.135	NM_000360 NM_199292 NM_199293	TH	tyrosine hydroxylase
chr2_+_97001463	0.133	NM_015341	NCAPH	non-SMC condensin I complex, subunit H
chr7_-_92463211	0.133	NM_001259	CDK6	cyclin-dependent kinase 6
chr1_+_212781969	0.133	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr6_-_34360098	0.133		NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr11_-_75921785	0.133		WNT11	wingless-type MMTV integration site family, member 11
chr4_-_100485173	0.132	NM_001134665 NM_001134666	RG9MTD2	RNA (guanine-9-) methyltransferase domain containing 2
chr7_-_100034050	0.131	NM_145030	PPP1R35	protein phosphatase 1, regulatory subunit 35
chr5_-_1882764	0.131	NM_016358	IRX4	iroquois homeobox 4
chr8_-_101964268	0.131		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr10_+_134210691	0.130	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.50	7.06e-29	GO:0044260	cellular macromolecule metabolic process
1.38	1.25e-28	GO:0044237	cellular metabolic process
1.18	6.31e-22	GO:0009987	cellular process
1.40	1.26e-21	GO:0043170	macromolecule metabolic process
1.32	3.06e-21	GO:0044238	primary metabolic process
1.29	6.87e-21	GO:0008152	metabolic process
1.54	4.79e-18	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49	2.35e-17	GO:0034641	cellular nitrogen compound metabolic process
1.46	1.48e-16	GO:0006807	nitrogen compound metabolic process
1.57	5.86e-15	GO:0090304	nucleic acid metabolic process
1.48	1.62e-12	GO:0044267	cellular protein metabolic process
1.56	2.30e-11	GO:0010467	gene expression
1.56	9.50e-11	GO:0016070	RNA metabolic process
1.74	4.63e-10	GO:0007049	cell cycle
2.00	7.16e-10	GO:0000278	mitotic cell cycle
1.81	3.04e-09	GO:0022402	cell cycle process
1.53	4.29e-09	GO:0009059	macromolecule biosynthetic process
1.88	5.43e-09	GO:0022403	cell cycle phase
1.48	9.84e-09	GO:0043412	macromolecule modification
1.52	1.81e-08	GO:0034645	cellular macromolecule biosynthetic process
1.49	2.09e-08	GO:0006464	protein modification process
1.41	2.33e-08	GO:0044249	cellular biosynthetic process
1.40	3.81e-08	GO:0009058	biosynthetic process
1.57	1.85e-07	GO:0051641	cellular localization
2.24	3.88e-07	GO:0051329	interphase of mitotic cell cycle
1.60	6.10e-07	GO:0051649	establishment of localization in cell
2.20	8.81e-07	GO:0051325	interphase
1.72	1.06e-06	GO:0046907	intracellular transport
1.33	1.27e-06	GO:0019538	protein metabolic process
1.29	1.99e-06	GO:0031323	regulation of cellular metabolic process
1.65	5.14e-06	GO:0015031	protein transport
1.76	5.45e-06	GO:0006396	RNA processing
1.59	9.17e-06	GO:0006793	phosphorus metabolic process
1.59	9.17e-06	GO:0006796	phosphate metabolic process
1.64	9.23e-06	GO:0045184	establishment of protein localization
1.49	2.10e-05	GO:0033036	macromolecule localization
1.25	3.25e-05	GO:0019222	regulation of metabolic process
1.60	4.29e-05	GO:0006351	transcription, DNA-dependent
1.28	5.88e-05	GO:0060255	regulation of macromolecule metabolic process
1.50	5.90e-05	GO:0031325	positive regulation of cellular metabolic process
1.31	7.67e-05	GO:0048518	positive regulation of biological process
1.52	1.05e-04	GO:0008104	protein localization
1.33	1.06e-04	GO:0048522	positive regulation of cellular process
1.48	1.12e-04	GO:0009893	positive regulation of metabolic process
1.41	1.18e-04	GO:0006996	organelle organization
1.26	1.27e-04	GO:0080090	regulation of primary metabolic process
3.17	2.70e-04	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
1.74	2.93e-04	GO:0044265	cellular macromolecule catabolic process
1.48	4.59e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.73	4.77e-04	GO:0016071	mRNA metabolic process
1.47	5.56e-04	GO:0044248	cellular catabolic process
1.14	7.26e-04	GO:0050789	regulation of biological process
1.25	7.60e-04	GO:0071840	cellular component organization or biogenesis
1.15	1.20e-03	GO:0050794	regulation of cellular process
1.28	1.46e-03	GO:0031326	regulation of cellular biosynthetic process
3.08	1.53e-03	GO:0034130	toll-like receptor 1 signaling pathway
3.08	1.53e-03	GO:0034134	toll-like receptor 2 signaling pathway
1.50	1.57e-03	GO:0032774	RNA biosynthetic process
1.28	1.59e-03	GO:0009889	regulation of biosynthetic process
1.28	1.84e-03	GO:0071841	cellular component organization or biogenesis at cellular level
2.83	1.90e-03	GO:0002224	toll-like receptor signaling pathway
1.54	2.05e-03	GO:0033554	cellular response to stress
1.87	2.21e-03	GO:0070647	protein modification by small protein conjugation or removal
2.92	2.67e-03	GO:0034142	toll-like receptor 4 signaling pathway
1.13	3.16e-03	GO:0065007	biological regulation
1.91	3.21e-03	GO:0000087	M phase of mitotic cell cycle
1.90	3.62e-03	GO:0048285	organelle fission
1.74	4.29e-03	GO:0000279	M phase
3.08	4.77e-03	GO:0034138	toll-like receptor 3 signaling pathway
2.70	5.06e-03	GO:0002221	pattern recognition receptor signaling pathway
1.90	6.00e-03	GO:0000280	nuclear division
1.90	6.00e-03	GO:0007067	mitosis
1.91	6.93e-03	GO:0032446	protein modification by small protein conjugation
2.99	8.46e-03	GO:0002756	MyD88-independent toll-like receptor signaling pathway
1.45	9.20e-03	GO:0032268	regulation of cellular protein metabolic process
1.26	9.55e-03	GO:0051171	regulation of nitrogen compound metabolic process
2.61	1.00e-02	GO:0002758	innate immune response-activating signal transduction
2.35	1.01e-02	GO:0006470	protein dephosphorylation
2.80	1.02e-02	GO:0008063	Toll signaling pathway
1.59	1.10e-02	GO:0009057	macromolecule catabolic process
1.43	1.15e-02	GO:0051246	regulation of protein metabolic process
1.27	1.36e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.35	1.41e-02	GO:0006403	RNA localization
1.37	1.53e-02	GO:0035556	intracellular signal transduction
2.56	1.55e-02	GO:0002218	activation of innate immune response
1.26	1.85e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.20	1.95e-02	GO:0023052	signaling
2.35	1.98e-02	GO:0050657	nucleic acid transport
2.35	1.98e-02	GO:0050658	RNA transport
2.35	1.98e-02	GO:0051236	establishment of RNA localization
2.42	2.20e-02	GO:0000086	G2/M transition of mitotic cell cycle
1.35	2.55e-02	GO:0009056	catabolic process
2.40	2.67e-02	GO:0051028	mRNA transport
1.47	2.96e-02	GO:0009891	positive regulation of biosynthetic process
1.21	3.02e-02	GO:0016043	cellular component organization
1.61	3.39e-02	GO:0070727	cellular macromolecule localization
2.20	3.39e-02	GO:0016311	dephosphorylation
1.47	3.41e-02	GO:0016310	phosphorylation
1.47	3.41e-02	GO:0031328	positive regulation of cellular biosynthetic process
1.71	3.51e-02	GO:0006397	mRNA processing
1.48	3.97e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.95	4.48e-02	GO:0000075	cell cycle checkpoint
1.60	4.78e-02	GO:0034613	cellular protein localization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.21	1.59e-34	GO:0044424	intracellular part
1.19	8.94e-33	GO:0005622	intracellular
1.26	1.25e-26	GO:0043227	membrane-bounded organelle
1.26	1.28e-26	GO:0043231	intracellular membrane-bounded organelle
1.22	2.24e-25	GO:0043226	organelle
1.22	2.70e-25	GO:0043229	intracellular organelle
1.74	2.80e-22	GO:0031981	nuclear lumen
1.35	4.10e-22	GO:0005634	nucleus
1.64	1.77e-21	GO:0070013	intracellular organelle lumen
1.24	3.60e-21	GO:0005737	cytoplasm
1.65	4.34e-21	GO:0044428	nuclear part
1.62	1.05e-20	GO:0043233	organelle lumen
1.61	1.66e-20	GO:0031974	membrane-enclosed lumen
1.32	2.35e-17	GO:0044446	intracellular organelle part
1.31	3.33e-17	GO:0044422	organelle part
1.77	1.55e-16	GO:0005654	nucleoplasm
1.51	3.55e-12	GO:0005829	cytosol
1.35	3.97e-11	GO:0032991	macromolecular complex
1.23	4.33e-10	GO:0044444	cytoplasmic part
1.37	7.66e-09	GO:0043228	non-membrane-bounded organelle
1.37	7.66e-09	GO:0043232	intracellular non-membrane-bounded organelle
1.34	2.28e-08	GO:0043234	protein complex
1.79	4.57e-08	GO:0015630	microtubule cytoskeleton
1.71	7.48e-07	GO:0044451	nucleoplasm part
2.03	2.57e-06	GO:0005815	microtubule organizing center
1.80	7.04e-06	GO:0005730	nucleolus
1.71	4.41e-05	GO:0005694	chromosome
1.75	1.52e-04	GO:0044427	chromosomal part
5.65	1.91e-04	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.65	1.14e-03	GO:0030529	ribonucleoprotein complex
1.04	1.18e-02	GO:0044464	cell part
1.04	1.22e-02	GO:0005623	cell

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.30	1.50e-25	GO:0005515	protein binding
1.15	1.96e-19	GO:0005488	binding
1.56	6.94e-17	GO:0000166	nucleotide binding
1.63	7.82e-17	GO:0032553	ribonucleotide binding
1.63	7.82e-17	GO:0032555	purine ribonucleotide binding
1.62	9.83e-17	GO:0017076	purine nucleotide binding
1.62	3.01e-16	GO:0035639	purine ribonucleoside triphosphate binding
1.64	1.15e-13	GO:0032559	adenyl ribonucleotide binding
1.64	1.23e-13	GO:0030554	adenyl nucleotide binding
1.63	4.15e-13	GO:0005524	ATP binding
1.77	1.50e-09	GO:0003723	RNA binding
1.31	9.11e-08	GO:0003676	nucleic acid binding
1.20	4.86e-06	GO:0003824	catalytic activity
1.58	7.44e-06	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.83	2.76e-05	GO:0004674	protein serine/threonine kinase activity
1.62	3.14e-05	GO:0017111	nucleoside-triphosphatase activity
1.59	4.75e-05	GO:0016462	pyrophosphatase activity
1.59	6.01e-05	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.58	7.60e-05	GO:0016817	hydrolase activity, acting on acid anhydrides
1.59	1.43e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.55	4.17e-04	GO:0016301	kinase activity
1.62	4.35e-04	GO:0004672	protein kinase activity
2.28	4.80e-04	GO:0004721	phosphoprotein phosphatase activity
1.45	1.61e-03	GO:0030528	transcription regulator activity
1.93	3.24e-03	GO:0016791	phosphatase activity
1.43	4.09e-03	GO:0001071	nucleic acid binding transcription factor activity
1.43	4.09e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.77	4.28e-03	GO:0042578	phosphoric ester hydrolase activity
3.36	5.72e-03	GO:0004722	protein serine/threonine phosphatase activity
1.30	1.04e-02	GO:0016740	transferase activity
1.48	2.40e-02	GO:0043565	sequence-specific DNA binding
1.89	3.14e-02	GO:0003924	GTPase activity
1.81	4.86e-02	GO:0019787	small conjugating protein ligase activity