Motif ID: CCUUCAU

Z-value: 0.315


Mature miRNA associated with seed CCUUCAU:

NamemiRBase Accession
hsa-miR-205 MIMAT0000266



Activity profile for motif CCUUCAU.

activity profile for motif CCUUCAU


Sorted Z-values histogram for motif CCUUCAU

Sorted Z-values for motif CCUUCAU



Network of associatons between targets according to the STRING database.



First level regulatory network of CCUUCAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_16884745 0.265 NM_181723
EFHA2
EF-hand domain family, member A2
chr2_-_202316227 0.199 NM_015049
TRAK2
trafficking protein, kinesin binding 2
chr10_-_21463019 0.163 NM_001173484
NM_213569
NEBL

nebulette

chr4_+_15004297 0.163 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr9_-_138987096 0.147 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr11_+_71935824 0.140 NM_001567
INPPL1
inositol polyphosphate phosphatase-like 1
chr6_+_114178516 0.139 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr20_+_11898536 0.137 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr8_-_95961543 0.124 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr2_-_145277879 0.122 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr10_-_21186530 0.121 NM_006393
NEBL
nebulette
chr20_+_11871364 0.116 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr8_-_12973752 0.116 NM_001164271
DLC1
deleted in liver cancer 1
chr8_-_12990731 0.109 NM_006094
DLC1
deleted in liver cancer 1
chr12_+_57522247 0.109 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr10_+_31608097 0.106 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr10_+_31610063 0.098 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr10_+_102295572 0.095 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr2_-_175869910 0.091 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr2_-_175712276 0.086 NM_001206602
CHN1
chimerin (chimaerin) 1
chr6_-_85473898 0.085 NM_001080508
TBX18
T-box 18
chr3_+_20081523 0.084 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr5_+_119800004 0.083 NM_016644
PRR16
proline rich 16
chr3_+_185000714 0.082 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr4_+_124317884 0.078 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr4_+_124320664 0.076 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr11_-_70507911 0.075 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr11_-_70935807 0.074 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr17_+_64298844 0.074 NM_002737
PRKCA
protein kinase C, alpha
chr8_-_60031545 0.074 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr11_-_108368918 0.072 NM_153705
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr8_+_70405027 0.072 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr15_+_89631380 0.070 NM_007011
NM_152924
ABHD2

abhydrolase domain containing 2

chr10_+_104613966 0.069 NM_001136200
NM_144591
C10orf32-AS3MT
C10orf32

C10orf32-AS3MT readthrough
chromosome 10 open reading frame 32

chr6_-_52441815 0.069 NM_012288
TRAM2
translocation associated membrane protein 2
chr19_+_35168558 0.068 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr2_+_238395863 0.068 NM_001042467
NM_024101
MLPH

melanophilin

chr15_-_49338496 0.066 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chrX_-_103087106 0.066 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr2_+_102770401 0.066 NM_000877
IL1R1
interleukin 1 receptor, type I
chr8_-_37756971 0.065 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr10_+_8096633 0.065 NM_001002295
NM_002051
GATA3

GATA binding protein 3

chr5_+_32711437 0.064 NM_000908
NM_001204375
NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

chr4_-_39640461 0.064 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr5_+_32710742 0.064 NM_001204376
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_-_79472360 0.064 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr5_-_38556682 0.061 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr8_+_70378858 0.060 NM_001128204
NM_015170
SULF1

sulfatase 1

chr20_-_39928708 0.060 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr14_-_89883306 0.060 NM_005197
FOXN3
forkhead box N3
chr12_-_29936685 0.060 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr15_-_60919642 0.059 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr4_+_77870864 0.058 NM_018243
SEPT11
septin 11
chr5_-_38595506 0.058 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr12_-_29937691 0.057 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr20_+_12989616 0.056 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr22_-_29075708 0.056 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr12_+_32654976 0.054 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr15_-_60884615 0.054 NM_134262
RORA
RAR-related orphan receptor A
chr17_-_37607314 0.054 NM_004774
MED1
mediator complex subunit 1
chr7_+_90338711 0.053 NM_012395
CDK14
cyclin-dependent kinase 14
chr4_-_185747183 0.053 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr6_-_111136407 0.053 NM_015076
CDK19
cyclin-dependent kinase 19
chr12_-_63328663 0.052 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_+_108882068 0.052 NM_001455
FOXO3
forkhead box O3
chr3_+_170136652 0.051 NM_005602
CLDN11
claudin 11
chr3_+_170139027 0.051 NM_001185056
CLDN11
claudin 11
chr2_+_24807345 0.051 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr4_+_81187741 0.051 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr14_-_90085325 0.051 NM_001085471
FOXN3
forkhead box N3
chr8_-_23712297 0.050 NM_003155
STC1
stanniocalcin 1
chr11_-_74109417 0.050 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr9_-_116163578 0.050 NM_000031
ALAD
aminolevulinate dehydratase
chr13_-_74707913 0.049 NM_007249
KLF12
Kruppel-like factor 12
chr3_+_185080835 0.049 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr17_+_76000248 0.048 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr1_+_110009099 0.046 NM_001040709
SYPL2
synaptophysin-like 2
chr9_-_22009270 0.045 NM_004936
NM_078487
CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr16_+_4421774 0.045 NM_138440
VASN
vasorin
chr19_-_7293876 0.043 NM_000208
NM_001079817
INSR

insulin receptor

chr6_+_108881010 0.043 NM_201559
FOXO3
forkhead box O3
chr9_-_113800243 0.041 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr14_-_53620032 0.040 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr3_+_42695175 0.039 NM_145166
ZBTB47
zinc finger and BTB domain containing 47
chr10_+_124768401 0.039 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr14_+_55034329 0.039 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr7_-_139477437 0.039 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr16_+_4674819 0.039 NM_001142289
NM_001142290
NM_001142291
NM_015246
MGRN1



mahogunin, ring finger 1



chrX_-_71351750 0.038 NM_001024455
RGAG4
retrotransposon gag domain containing 4
chr5_-_138775213 0.038 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chrX_+_7137471 0.038 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr1_-_145470353 0.038 NM_032305
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr14_-_80677839 0.037 NM_001007023
NM_001242502
NM_001242503
NM_013989
DIO2



deiodinase, iodothyronine, type II



chr1_-_31381436 0.037 NM_014654
SDC3
syndecan 3
chr13_-_114898084 0.037 NM_007368
RASA3
RAS p21 protein activator 3
chr3_-_187454247 0.037 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr1_-_208417635 0.036 NM_025179
PLXNA2
plexin A2
chr12_+_40618786 0.035 NM_198578
LRRK2
leucine-rich repeat kinase 2
chr5_-_41510627 0.034 NM_001005473
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr7_+_102073953 0.034 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr12_+_15699277 0.034 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr3_-_127541975 0.034 NM_001003794
MGLL
monoglyceride lipase
chr14_-_89020888 0.034 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr5_+_169010637 0.034 NM_017785
CCDC99
coiled-coil domain containing 99
chr14_-_80697396 0.033 NM_000793
DIO2
deiodinase, iodothyronine, type II
chr19_+_35225479 0.033 NM_001029997
NM_001145665
ZNF181

zinc finger protein 181

chr22_+_22020272 0.032 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr3_+_141043054 0.032 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr6_+_11538486 0.032 NM_001100829
TMEM170B
transmembrane protein 170B
chr17_-_62502410 0.032 NM_004396
DDX5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr1_+_164528586 0.032 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr3_-_127541160 0.032 NM_007283
MGLL
monoglyceride lipase
chr17_-_16472463 0.032 NM_020653
ZNF287
zinc finger protein 287
chr16_+_69599868 0.031 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr18_+_7567313 0.031 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr3_-_187463474 0.031 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr6_-_116575170 0.031 NM_021648
TSPYL4
TSPY-like 4
chr9_+_107509948 0.030 NM_015469
NIPSNAP3A
nipsnap homolog 3A (C. elegans)
chr14_-_69619870 0.030 NM_003861
DCAF5
DDB1 and CUL4 associated factor 5
chr4_+_2470777 0.030 NM_001185010
NM_002938
RNF4

ring finger protein 4

chr20_+_5107393 0.030 NM_003818
CDS2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr15_+_91643429 0.030 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr15_+_83776323 0.030 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr17_+_58755158 0.030 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr3_-_187452669 0.029 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr20_+_33462765 0.029 NM_001242393
ACSS2
acyl-CoA synthetase short-chain family member 2
chr3_+_187930720 0.029 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_33168356 0.029 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr14_+_72398816 0.028 NM_001204423
RGS6
regulator of G-protein signaling 6
chr2_-_99347588 0.028 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_-_57520326 0.028 NM_018110
DOK4
docking protein 4
chr12_+_15475190 0.028 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr1_+_178310605 0.028 NM_004841
RASAL2
RAS protein activator like 2
chr7_+_7222142 0.028 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr16_-_87525317 0.028 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr7_-_23571443 0.028 NM_013293
TRA2A
transformer 2 alpha homolog (Drosophila)
chr20_+_54933982 0.028 NM_080821
FAM210B
family with sequence similarity 210, member B
chr2_+_201997687 0.027 NM_001202518
CFLAR
CASP8 and FADD-like apoptosis regulator
chr4_+_2471179 0.027 NM_001185009
RNF4
ring finger protein 4
chr20_+_33464327 0.027 NM_001076552
NM_018677
ACSS2

acyl-CoA synthetase short-chain family member 2

chr7_+_90893735 0.027 NM_003505
FZD1
frizzled family receptor 1
chrX_-_15873094 0.027 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr5_-_73937248 0.027 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr12_+_64238511 0.027 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr6_+_158589378 0.027 NM_207118
GTF2H5
general transcription factor IIH, polypeptide 5
chr20_-_35402142 0.026 NM_001145316
NM_024918
NM_001145315
NM_001145317
NM_001145318
DSN1




DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)




chr14_-_65438794 0.026 NM_198686
RAB15
RAB15, member RAS onocogene family
chr7_-_14025826 0.026 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr16_-_25268841 0.026 NM_001012981
ZKSCAN2
zinc finger with KRAB and SCAN domains 2
chr5_-_58334936 0.026 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr17_+_44668034 0.026 NM_006178
NSF
N-ethylmaleimide-sensitive factor
chr3_+_187871473 0.026 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr13_-_24007822 0.026 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr11_+_12399024 0.025 NM_018222
PARVA
parvin, alpha
chr1_+_101361589 0.025 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr20_-_443172 0.025 NM_144628
TBC1D20
TBC1 domain family, member 20
chr15_-_93198602 0.025 NM_207446
FAM174B
family with sequence similarity 174, member B
chr18_+_48086402 0.024 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr12_+_56367696 0.024 NM_001252036
NM_001252037
NM_002868
RAB5B


RAB5B, member RAS oncogene family


chr19_+_58258160 0.024 NM_173632
ZNF776
zinc finger protein 776
chr6_+_45389818 0.024 NM_004348
RUNX2
runt-related transcription factor 2
chr11_+_6502607 0.024 NM_012192
FXC1
fracture callus 1 homolog (rat)
chr7_-_14029641 0.024 NM_001163147
NM_004956
ETV1

ets variant 1

chr1_-_241803203 0.024 NM_014322
OPN3
opsin 3
chr7_-_14031049 0.024 NM_001163148
ETV1
ets variant 1
chr17_-_74236272 0.024 NM_052916
RNF157
ring finger protein 157
chr15_-_61521478 0.024 NM_134261
RORA
RAR-related orphan receptor A
chr8_+_41435666 0.024 NM_178819
AGPAT6
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
chr17_+_33570079 0.023 NM_144975
SLFN5
schlafen family member 5
chr19_-_58400287 0.023 NM_001144989
ZNF814
zinc finger protein 814
chr20_-_3388219 0.023 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr7_-_14030864 0.023 NM_001163149
ETV1
ets variant 1
chr12_+_44152746 0.023 NM_001114182
NM_001145256
NM_001145257
NM_001145258
NM_016123
IRAK4




interleukin-1 receptor-associated kinase 4




chr17_+_260092 0.023 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr19_+_10123861 0.023 NM_015725
RDH8
retinol dehydrogenase 8 (all-trans)
chr2_-_188312872 0.023 NM_005795
CALCRL
calcitonin receptor-like
chr14_+_55221505 0.022 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr3_+_187943192 0.022 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_+_35965530 0.022 NM_174902
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr17_-_42908178 0.022 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr11_+_12695851 0.022 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr13_+_43597338 0.022 NM_013238
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr13_+_44453968 0.022 NM_153218
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr4_-_5894695 0.022 NM_001014809
CRMP1
collapsin response mediator protein 1
chr6_+_52226866 0.021 NM_133367
PAQR8
progestin and adipoQ receptor family member VIII
chr2_+_205410465 0.021 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr2_-_171923482 0.021 NM_001136555
TLK1
tousled-like kinase 1
chr9_-_14398981 0.021 NM_001190738
NFIB
nuclear factor I/B
chr5_+_54455945 0.021 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr4_-_5890266 0.021 NM_001313
CRMP1
collapsin response mediator protein 1
chr2_+_74741565 0.021 NM_016170
TLX2
T-cell leukemia homeobox 2
chr5_-_59783885 0.021 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_116681103 0.021 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr3_-_122134881 0.021 NM_019069
WDR5B
WD repeat domain 5B
chr2_-_219432955 0.021 NM_020935
USP37
ubiquitin specific peptidase 37
chr17_-_45899133 0.021 NM_145798
OSBPL7
oxysterol binding protein-like 7
chr1_-_33841142 0.021 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr1_+_178062829 0.021 NM_170692
RASAL2
RAS protein activator like 2
chr19_-_58220535 0.021 NM_001085384
ZNF154
zinc finger protein 154
chr3_-_122233781 0.020 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.40 2.27e-03 GO:0044260 cellular macromolecule metabolic process
1.58 3.33e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.55 4.26e-03 GO:0010468 regulation of gene expression
1.27 8.45e-03 GO:0050794 regulation of cellular process
1.54 1.06e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.39 1.55e-02 GO:0019222 regulation of metabolic process
1.42 1.64e-02 GO:0031323 regulation of cellular metabolic process
1.50 1.72e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 2.79e-02 GO:0060255 regulation of macromolecule metabolic process
1.49 2.89e-02 GO:0031326 regulation of cellular biosynthetic process
1.22 2.92e-02 GO:0065007 biological regulation
1.41 3.38e-02 GO:0080090 regulation of primary metabolic process
1.23 3.53e-02 GO:0050789 regulation of biological process
1.47 3.75e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.47 4.63e-02 GO:0009889 regulation of biosynthetic process
2.31 4.82e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 6.33e-04 GO:0005622 intracellular
1.15 1.30e-03 GO:0044424 intracellular part
1.18 1.99e-03 GO:0043226 organelle
1.18 2.51e-03 GO:0043229 intracellular organelle
1.21 3.44e-03 GO:0005737 cytoplasm
1.51 1.92e-02 GO:0005829 cytosol
1.18 2.78e-02 GO:0043231 intracellular membrane-bounded organelle
1.18 3.06e-02 GO:0043227 membrane-bounded organelle
4.08 4.55e-02 GO:0030027 lamellipodium
2.15 4.84e-02 GO:0005768 endosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 3.02e-04 GO:0005488 binding
1.26 8.68e-04 GO:0005515 protein binding
2.08 1.87e-03 GO:0019899 enzyme binding