Motif ID: CDC5L.p2

Z-value: 0.637


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_44355440-0.658.1e-02Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_62362838 0.575 NM_015236
LPHN3
latrophilin 3
chr21_-_31852631 0.472 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr10_+_111765725 0.409 NM_019903
ADD3
adducin 3 (gamma)
chr6_-_155777036 0.385 NM_015718
NOX3
NADPH oxidase 3
chr9_-_95298251 0.352 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr10_-_21186530 0.330 NM_006393
NEBL
nebulette
chr15_+_72406598 0.318 NM_001166340
SENP8
SUMO/sentrin specific peptidase family member 8
chrX_+_103031753 0.315 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr6_-_24583454 0.306 NM_001252328
KIAA0319
KIAA0319
chr17_-_19290471 0.290 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chrX_+_103031797 0.290 PLP1
proteolipid protein 1
chr4_+_41614933 0.287 LIMCH1
LIM and calponin homology domains 1
chr9_-_95166827 0.276 NM_014057
NM_033014
OGN

osteoglycin

chr2_+_210444364 0.265 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr3_-_121379701 0.259 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr4_-_100242487 0.246 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr8_+_1952875 0.243 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr10_+_49609641 0.235 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr18_+_616671 0.234 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr2_-_211179765 0.229 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr11_-_13517525 0.229 NM_000315
PTH
parathyroid hormone
chr1_-_89591685 0.225 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr4_-_159093717 0.220 NM_016613
FAM198B
family with sequence similarity 198, member B
chr2_+_166095911 0.216 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr3_-_108672547 0.214 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr8_+_75736771 0.207 NM_015886
PI15
peptidase inhibitor 15
chr1_+_196621007 0.203 NM_000186
NM_001014975
CFH

complement factor H

chrX_+_135230736 0.187 NM_001159700
FHL1
four and a half LIM domains 1
chr4_+_41614911 0.187 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chrX_+_102585113 0.179 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr15_-_99789585 0.175 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr3_+_122044010 0.170 NM_005213
CSTA
cystatin A (stefin A)
chr1_+_59775749 0.169 NM_001244714
FGGY
FGGY carbohydrate kinase domain containing
chr4_-_138453628 0.168 NM_019035
PCDH18
protocadherin 18
chr1_-_23886284 0.164 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr5_+_161277702 0.162 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr9_+_12774988 0.155 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr21_+_30517897 0.155 C21orf7
chromosome 21 open reading frame 7
chr20_+_20037289 0.151 NM_001167816
C20orf26
chromosome 20 open reading frame 26
chr6_-_32812711 0.148 NM_004159
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr1_+_244515936 0.147 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chr1_+_79115476 0.145 NM_006417
IFI44
interferon-induced protein 44
chr5_+_115898218 0.143


chr10_-_70066594 0.141 PBLD
phenazine biosynthesis-like protein domain containing
chr6_-_111894897 0.138 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr22_+_29168679 0.135 CCDC117
coiled-coil domain containing 117
chr14_-_101036130 0.135 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr3_-_93747453 0.134 NM_001001850
STX19
syntaxin 19
chr17_-_66951381 0.134 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr14_+_70918873 0.133 NM_003813
ADAM21
ADAM metallopeptidase domain 21
chr3_-_64672285 0.129 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr2_+_167744996 0.126 NM_001079810
NM_001199143
NM_152381
XIRP2


xin actin-binding repeat containing 2


chr4_+_41614725 0.124 LIMCH1
LIM and calponin homology domains 1
chr21_+_48055077 0.121 PRMT2
protein arginine methyltransferase 2
chr4_-_140060601 0.121 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr11_-_57335756 0.120 NM_198183
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr12_-_91398744 0.117 EPYC
epiphycan
chr12_-_91398757 0.115 NM_004950
EPYC
epiphycan
chr1_+_229440128 0.114 NM_006542
SPHAR
S-phase response (cyclin related)
chr3_-_151034514 0.113 NM_023915
GPR87
G protein-coupled receptor 87
chr12_+_21525801 0.112 NM_000415
IAPP
islet amyloid polypeptide
chr19_-_10426673 0.111 NM_001031734
FDX1L
ferredoxin 1-like
chr10_+_126630691 0.110 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr4_-_110723127 0.105 CFI
complement factor I
chr12_+_80603232 0.105 NM_173591
OTOGL
otogelin-like
chrX_+_85517970 0.104 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr5_+_54398473 0.104 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr7_-_100076754 0.103 NM_030935
TSC22D4
TSC22 domain family, member 4
chr4_+_130017281 0.103 NM_001099783
C4orf33
chromosome 4 open reading frame 33
chr7_+_94297448 0.103 PEG10
paternally expressed 10
chr9_+_135854097 0.102 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr18_+_61582744 0.101 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr11_+_101983170 0.098 NM_001195045
YAP1
Yes-associated protein 1
chr9_+_125273080 0.096 NM_054107
OR1J2
olfactory receptor, family 1, subfamily J, member 2
chr22_+_29168628 0.094 NM_173510
CCDC117
coiled-coil domain containing 117
chr2_+_228192227 0.094 NM_020194
MFF
mitochondrial fission factor
chr4_+_119948554 0.093 SYNPO2
synaptopodin 2
chr6_-_46293404 0.092 RCAN2
regulator of calcineurin 2
chr10_+_5136589 0.091 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chrX_+_80457559 0.090 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr10_+_5136613 0.090 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr6_-_134373618 0.089 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr1_+_84767288 0.089 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr10_-_116444374 0.088 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr17_-_7493389 0.088 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr15_-_31947541 0.088 NM_130901
OTUD7A
OTU domain containing 7A
chr4_-_186732047 0.088 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr14_-_20801427 0.088 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr7_-_16921596 0.088 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr20_-_1974393 0.087 NM_001190900
PDYN
prodynorphin
chr13_-_86373328 0.087 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr10_+_5136556 0.086 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_-_29624249 0.085 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr7_+_143412938 0.084 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr6_-_132967141 0.084 NM_138327
TAAR1
trace amine associated receptor 1
chr6_-_32557431 0.083 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr21_+_38455246 0.083 NM_003316
TTC3
tetratricopeptide repeat domain 3
chr19_-_4540078 0.082 LRG1
leucine-rich alpha-2-glycoprotein 1
chr4_+_86396251 0.081 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr10_-_74283693 0.081 NM_001195519
MICU1
mitochondrial calcium uptake 1
chr1_+_236557643 0.080 NM_145861
EDARADD
EDAR-associated death domain
chr10_+_91061705 0.079 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr17_-_19651586 0.079 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr4_-_87028805 0.078 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr1_-_182357757 0.078 GLUL
glutamate-ammonia ligase
chr8_-_110693233 0.078 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr5_+_54320083 0.078 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr1_-_144997110 0.078 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_-_57234279 0.077 NM_003865
HESX1
HESX homeobox 1
chr9_-_19786886 0.077 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr3_-_169587598 0.077 NM_024727
LRRC31
leucine rich repeat containing 31
chr3_-_114790221 0.076 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_70725792 0.076 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr20_-_34241830 0.075 NM_003915
CPNE1
copine I
chr1_+_202431870 0.075 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr6_+_132891460 0.074 NM_175067
TAAR6
trace amine associated receptor 6
chr4_-_186577858 0.074 SORBS2
sorbin and SH3 domain containing 2
chr21_+_27011588 0.073 NM_021219
JAM2
junctional adhesion molecule 2
chr1_-_231005334 0.073 NM_001136494
C1orf198
chromosome 1 open reading frame 198
chrX_+_80457597 0.073 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr3_-_49726081 0.073 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr10_+_91152321 0.072 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chrX_+_135278912 0.072 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr4_-_152149042 0.072 NM_001243349
SH3D19
SH3 domain containing 19
chr4_+_15471488 0.072 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr2_+_61389628 0.072 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr10_-_116286661 0.072 NM_006720
ABLIM1
actin binding LIM protein 1
chr6_+_136172802 0.072 NM_018945
PDE7B
phosphodiesterase 7B
chr11_-_114466397 0.072 FAM55D
family with sequence similarity 55, member D
chr1_-_198510074 0.072 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr3_-_138478184 0.070 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chrX_+_106171328 0.070 CLDN2
claudin 2
chr6_+_127898318 0.069 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr10_-_116444112 0.069 ABLIM1
actin binding LIM protein 1
chr1_+_84768333 0.068 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr17_+_37856224 0.067 ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chrX_+_135251795 0.067 NM_001167819
FHL1
four and a half LIM domains 1
chr2_+_33661392 0.064 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_211458078 0.064 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr6_+_72926462 0.064 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr3_+_158787040 0.064 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr2_-_2334887 0.063 NM_015025
MYT1L
myelin transcription factor 1-like
chr13_+_97928414 0.062 MBNL2
muscleblind-like 2 (Drosophila)
chr9_+_5890801 0.062 NM_005511
MLANA
melan-A
chr12_+_100897137 0.061 NM_001206992
NM_001206993
NR1H4

nuclear receptor subfamily 1, group H, member 4

chr4_-_87281374 0.061 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr6_+_28234787 0.061 NM_001023560
NM_001111039
NM_152736
ZNF187


zinc finger protein 187


chr10_-_69425356 0.060 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr7_-_14025826 0.060 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr14_-_21058388 0.060 NM_145250
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr13_+_97794050 0.059 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_241695433 0.058 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_84874033 0.058 NM_058248
DNASE2B
deoxyribonuclease II beta
chrX_-_24690740 0.058 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr14_-_81864726 0.058 NM_033104
STON2
stonin 2
chr1_+_43291230 0.057 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr2_+_79252825 0.056 NM_001008387
NM_198448
REG3G

regenerating islet-derived 3 gamma

chr1_-_204135420 0.055 NM_000537
REN
renin
chr20_+_2276612 0.055 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr4_-_152096655 0.055 NM_001128924
SH3D19
SH3 domain containing 19
chr11_-_85430117 0.055 NM_206929
SYTL2
synaptotagmin-like 2
chr15_+_80364902 0.055 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr5_+_140514787 0.055 NM_015669
PCDHB5
protocadherin beta 5
chr3_+_97158453 0.054 NM_173655
EPHA6
EPH receptor A6
chr2_+_103378489 0.054 NM_144632
TMEM182
transmembrane protein 182
chr1_-_163113129 0.054 RGS5
regulator of G-protein signaling 5
chr6_+_72926144 0.054 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr3_+_148447966 0.054 NM_032049
AGTR1
angiotensin II receptor, type 1
chr3_-_112218383 0.053 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr1_-_226926875 0.053 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr20_+_42984338 0.053 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr3_+_42190736 0.052 TRAK1
trafficking protein, kinesin binding 1
chr11_-_31014232 0.052 NM_020869
DCDC5
doublecortin domain containing 5
chr4_+_71108304 0.052 NM_005212
CSN3
casein kappa
chr4_-_89978117 0.052 NM_014883
FAM13A
family with sequence similarity 13, member A
chr1_+_10509775 0.052 NM_001302
CORT
cortistatin
chr3_-_187452669 0.052 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr7_-_14880954 0.052 NM_004080
NM_145695
DGKB

diacylglycerol kinase, beta 90kDa

chr5_+_42565963 0.051 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr8_+_107738239 0.051 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr1_-_146697155 0.050 NM_001144829
NM_001144830
NM_001461
FMO5


flavin containing monooxygenase 5


chr4_-_100273831 0.050 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr1_-_86043932 0.049 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_-_122339186 0.049 NM_139175
RNF133
ring finger protein 133
chr5_+_143191725 0.048 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr1_-_33647626 0.048 NM_018207
TRIM62
tripartite motif containing 62
chr10_-_98031154 0.048 NM_001114094
NM_013314
BLNK

B-cell linker

chr1_+_198608216 0.047 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_204571197 0.047 NM_001243077
NM_001243078
NM_006139
CD28


CD28 molecule


chr6_-_117747017 0.047 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr16_-_4896197 0.047 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr3_-_141747434 0.047 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr2_+_189839113 0.047 COL3A1
collagen, type III, alpha 1
chr6_-_136847078 0.046 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr1_+_50571963 0.046 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_-_108142934 0.045 PNPLA8
patatin-like phospholipase domain containing 8
chr2_+_189839078 0.045 NM_000090
COL3A1
collagen, type III, alpha 1
chr22_-_36236421 0.044 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr3_+_183353355 0.044 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chr9_-_13250313 0.044 NM_003829
MPDZ
multiple PDZ domain protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.04 3.62e-03 GO:0006955 immune response
2.50 8.02e-03 GO:0045087 innate immune response
1.24 2.03e-02 GO:0050896 response to stimulus
1.19 2.78e-02 GO:0065007 biological regulation
2.23 3.94e-02 GO:0050776 regulation of immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.47 1.15e-02 GO:0005576 extracellular region

Nothing significant found in function category.