Motif ID: CTCF.p2

Z-value: 0.880


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_675963090.551.6e-01Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_67360625 0.235 NM_001100915
KCTD19
potassium channel tetramerisation domain containing 19
chr22_+_31478845 0.217 NM_001207017
SMTN
smoothelin
chr2_-_232395108 0.191 NM_006056
NMUR1
neuromedin U receptor 1
chrX_+_152110214 0.187 NM_001178115
ZNF185
zinc finger protein 185 (LIM domain)
chr7_+_89783789 0.172 STEAP1
six transmembrane epithelial antigen of the prostate 1
chr22_-_22901421 0.171 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr5_+_98104998 0.162 NM_001012761
RGMB
RGM domain family, member B
chr1_+_212208918 0.157 NM_016448
DTL
denticleless homolog (Drosophila)
chr10_-_79789290 0.152 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr7_+_89783688 0.141 NM_012449
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr17_-_48474864 0.139 LRRC59
leucine rich repeat containing 59
chr10_-_15413054 0.135 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr1_+_28844762 0.132 RCC1
regulator of chromosome condensation 1
chr6_+_33359312 0.132 NM_002263
KIFC1
kinesin family member C1
chr9_-_117444368 0.129 NM_001199233
LOC100505478
uncharacterized LOC100505478
chr1_-_95699508 0.129


chr3_-_49757058 0.127 NM_198722
AMIGO3
adhesion molecule with Ig-like domain 3
chr10_-_79789164 0.126 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr17_+_34136437 0.125 NM_003487
NM_139215
TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

chr1_+_145524989 0.123 NM_003637
ITGA10
integrin, alpha 10
chr17_-_40833840 0.122 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr1_+_28844647 0.116 NM_001048194
NM_001048195
NM_001269
RCC1


regulator of chromosome condensation 1


chr5_+_148520985 0.110 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr10_+_13203547 0.108 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr2_-_158454025 0.107 NM_001111031
ACVR1C
activin A receptor, type IC
chr2_+_27309610 0.107 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr17_+_16318911 0.106 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr7_+_98476084 0.106 NM_001244580
NM_003496
TRRAP

transformation/transcription domain-associated protein

chr5_+_137688386 0.106 KDM3B
lysine (K)-specific demethylase 3B
chr4_+_56212456 0.106 SRD5A3
steroid 5 alpha-reductase 3
chr1_+_114447906 0.104 NM_022836
DCLRE1B
DNA cross-link repair 1B
chr17_+_16318848 0.103 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr1_+_212209112 0.101 DTL
denticleless homolog (Drosophila)
chr1_+_114448026 0.101 DCLRE1B
DNA cross-link repair 1B
chr17_+_42219235 0.099 NM_001171251
NM_024032
C17orf53

chromosome 17 open reading frame 53

chr14_-_24777160 0.099 CIDEB
cell death-inducing DFFA-like effector b
chr17_-_42441123 0.099 NM_198475
FAM171A2
family with sequence similarity 171, member A2
chrX_+_47053302 0.099 UBA1
ubiquitin-like modifier activating enzyme 1
chr14_-_24777153 0.098 CIDEB
cell death-inducing DFFA-like effector b
chr1_-_226595533 0.098 PARP1
poly (ADP-ribose) polymerase 1
chr12_+_110338064 0.097 NM_001143852
TCHP
trichoplein, keratin filament binding
chr19_+_4791757 0.097 FEM1A
fem-1 homolog a (C. elegans)
chr19_+_4791756 0.097 FEM1A
fem-1 homolog a (C. elegans)
chr4_-_6911373 0.096


chr17_-_72919244 0.096 NM_173477
USH1G
Usher syndrome 1G (autosomal recessive)
chr9_-_139258240 0.095 NM_001080849
DNLZ
DNL-type zinc finger
chr18_-_21166440 0.095 NM_000271
NPC1
Niemann-Pick disease, type C1
chr3_+_172468469 0.094 ECT2
epithelial cell transforming sequence 2 oncogene
chr1_-_114447635 0.094 NM_006594
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chrX_+_47053271 0.093 UBA1
ubiquitin-like modifier activating enzyme 1
chr14_-_24777184 0.093 CIDEB
cell death-inducing DFFA-like effector b
chr10_+_73571639 0.093 NM_001171935
NM_001171936
CDH23

cadherin-related 23

chr12_-_46384208 0.093 SCAF11
SR-related CTD-associated factor 11
chr3_-_167098070 0.092 NM_001199202
NM_001199201
NM_024687
ZBBX


zinc finger, B-box domain containing


chr19_+_4791727 0.092 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr4_-_110354914 0.089 1/2-SBSRNA4
lncRNA_BC009800
chr1_-_186344383 0.088 TPR
translocated promoter region (to activated MET oncogene)
chr11_-_66103874 0.088 NM_004292
RIN1
Ras and Rab interactor 1
chr1_-_114447338 0.087 AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr17_-_35716024 0.086 NM_198836
ACACA
acetyl-CoA carboxylase alpha
chr1_-_94375028 0.084 GCLM
glutamate-cysteine ligase, modifier subunit
chr20_+_60877939 0.083 ADRM1
adhesion regulating molecule 1
chr1_+_20208908 0.082 OTUD3
OTU domain containing 3
chr1_+_20208837 0.082 NM_015207
OTUD3
OTU domain containing 3
chr5_-_146833150 0.079 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr8_+_143808593 0.079 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr17_+_7591666 0.079 NM_001143992
NM_018081
WRAP53

WD repeat containing, antisense to TP53

chr12_+_110338322 0.079 NM_032300
TCHP
trichoplein, keratin filament binding
chr17_+_42219300 0.078 C17orf53
chromosome 17 open reading frame 53
chr9_+_127615695 0.078 NM_001045476
WDR38
WD repeat domain 38
chr1_-_186344330 0.078 TPR
translocated promoter region (to activated MET oncogene)
chr7_-_123174572 0.077 NM_178827
IQUB
IQ motif and ubiquitin domain containing
chr10_-_101769640 0.077 NM_015221
DNMBP
dynamin binding protein
chr11_+_64018991 0.077 NM_000932
NM_001184883
PLCB3

phospholipase C, beta 3 (phosphatidylinositol-specific)

chrX_+_47053234 0.077 UBA1
ubiquitin-like modifier activating enzyme 1
chr12_-_53715343 0.077 NM_001173466
NM_015665
AAAS

achalasia, adrenocortical insufficiency, alacrimia

chr19_+_1248548 0.076 NM_177401
MIDN
midnolin
chr1_+_151129104 0.076 NM_001204848
NM_024575
TNFAIP8L2-SCNM1
TNFAIP8L2
TNFAIP8L2-SCNM1 readthrough
tumor necrosis factor, alpha-induced protein 8-like 2
chr19_+_53073515 0.076 NM_018260
ZNF701
zinc finger protein 701
chr15_+_101390032 0.075 LOC145757
uncharacterized LOC145757
chr13_+_31774087 0.075 NM_194318
B3GALTL
beta 1,3-galactosyltransferase-like
chrX_+_77166223 0.074 ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr4_-_171011292 0.074 NM_182662
AADAT
aminoadipate aminotransferase
chrX_+_47053227 0.073 UBA1
ubiquitin-like modifier activating enzyme 1
chr12_+_51818669 0.073 SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr2_+_152266603 0.073 NM_001177665
RIF1
RAP1 interacting factor homolog (yeast)
chr2_+_231921595 0.073 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr8_+_67341244 0.073 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr18_-_57364572 0.072 CCBE1
collagen and calcium binding EGF domains 1
chr12_-_46384317 0.072 SCAF11
SR-related CTD-associated factor 11
chr20_+_60878024 0.072 NM_007002
NM_175573
ADRM1

adhesion regulating molecule 1

chr11_+_67034148 0.072 ADRBK1
adrenergic, beta, receptor kinase 1
chr20_+_60878048 0.072 ADRM1
adhesion regulating molecule 1
chr2_+_231921608 0.072 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr12_-_120703488 0.071 PXN
paxillin
chr12_-_109531244 0.071 NM_001001655
NM_001145374
NM_001145375
NM_001205179
NM_001205180
ALKBH2




alkB, alkylation repair homolog 2 (E. coli)




chr16_+_30406711 0.071 NM_152652
ZNF48
zinc finger protein 48
chr17_+_42219382 0.071 C17orf53
chromosome 17 open reading frame 53
chr14_-_107083398 0.071 IGH@
IGHA1
IGHG1
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_-_2390711 0.071 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chrX_-_117119282 0.071 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr1_-_6614584 0.070 NM_024654
NOL9
nucleolar protein 9
chr1_+_109289294 0.070 STXBP3
syntaxin binding protein 3
chr12_-_53715248 0.070 AAAS
achalasia, adrenocortical insufficiency, alacrimia
chr10_+_116581495 0.070 NM_001135051
NM_020940
FAM160B1

family with sequence similarity 160, member B1

chr11_+_64018996 0.070 PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr6_-_34216824 0.070 NM_001008703
NM_001008704
NM_178508
C6orf1


chromosome 6 open reading frame 1


chr1_-_6614552 0.070 NOL9
nucleolar protein 9
chr8_+_41386724 0.069 NM_032336
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr2_+_231921625 0.069 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr6_+_3849621 0.068 NM_012135
FAM50B
family with sequence similarity 50, member B
chr4_-_171011182 0.068 NM_016228
AADAT
aminoadipate aminotransferase
chr3_+_50297644 0.068


chrX_+_47053213 0.068 UBA1
ubiquitin-like modifier activating enzyme 1
chr1_-_226595790 0.068 PARP1
poly (ADP-ribose) polymerase 1
chr16_+_21695749 0.068 NM_001161683
OTOA
otoancorin
chr10_+_6244839 0.067 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_-_120703549 0.067 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr16_-_2390593 0.066 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr13_+_33160537 0.066 NM_015032
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr1_+_10093149 0.066 UBE4B
ubiquitination factor E4B
chr5_-_136834887 0.065 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_-_94374949 0.065 GCLM
glutamate-cysteine ligase, modifier subunit
chr11_+_67033929 0.065 ADRBK1
adrenergic, beta, receptor kinase 1
chr11_+_67034164 0.065 ADRBK1
adrenergic, beta, receptor kinase 1
chr1_+_159175048 0.064 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr1_-_186344389 0.064 NM_003292
TPR
translocated promoter region (to activated MET oncogene)
chr3_+_101568325 0.064 NM_031419
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr7_-_38375172 0.064 TRGV7
T cell receptor gamma variable 7 (pseudogene)
chrX_+_47053192 0.063 NM_003334
UBA1
ubiquitin-like modifier activating enzyme 1
chr16_-_2390737 0.063 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr4_+_56815036 0.063 NM_025009
CEP135
centrosomal protein 135kDa
chr16_-_22012427 0.062 NM_173806
PDZD9
PDZ domain containing 9
chr11_-_798196 0.062 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr19_-_1876133 0.062


chr5_-_122759003 0.062 NM_001166226
NM_153223
CEP120

centrosomal protein 120kDa

chr2_+_231921562 0.062 NM_001191037
NM_002807
PSMD1

proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

chr17_+_38137088 0.061 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chrX_-_153141284 0.061 L1CAM
L1 cell adhesion molecule
chr17_+_21308447 0.061 NM_001194958
KCNJ18
potassium inwardly-rectifying channel, subfamily J, member 18
chr1_-_26324534 0.061 NM_000437
PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
chr11_+_67033889 0.061 NM_001619
ADRBK1
adrenergic, beta, receptor kinase 1
chr3_-_186857188 0.061 NM_052969
RPL39L
ribosomal protein L39-like
chr6_+_151187064 0.060 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr4_+_56212381 0.060 NM_024592
SRD5A3
steroid 5 alpha-reductase 3
chr16_+_53088791 0.060 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr8_-_145550300 0.060 DGAT1
diacylglycerol O-acyltransferase 1
chr15_+_75074714 0.059 CSK
c-src tyrosine kinase
chr13_+_33160610 0.058 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr2_+_103089761 0.058 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr17_+_38137106 0.057 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr17_+_38137081 0.057 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr3_+_577913 0.057


chr22_-_22307188 0.057 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr22_-_50682915 0.057 TUBGCP6
tubulin, gamma complex associated protein 6
chr6_-_159240399 0.056 EZR
ezrin
chr6_-_159240398 0.056 EZR
ezrin
chr12_-_56583301 0.055 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr11_+_117103237 0.054 NM_207343
NM_001077239
RNF214

ring finger protein 214

chr1_-_186344241 0.054 TPR
translocated promoter region (to activated MET oncogene)
chr2_-_120282060 0.054 SCTR
secretin receptor
chr7_-_14030864 0.054 NM_001163149
ETV1
ets variant 1
chr17_-_73900934 0.054 MRPL38
mitochondrial ribosomal protein L38
chr1_-_226595684 0.054 PARP1
poly (ADP-ribose) polymerase 1
chr17_+_28705960 0.053 CPD
carboxypeptidase D
chr19_+_58341661 0.053 NM_001204818
LOC100293516
zinc finger protein
chr8_-_145550516 0.053 DGAT1
diacylglycerol O-acyltransferase 1
chr6_-_131949188 0.053 NM_004830
NM_015979
MED23

mediator complex subunit 23

chr19_-_49496369 0.053 GYS1
glycogen synthase 1 (muscle)
chr6_-_34216765 0.052 C6orf1
chromosome 6 open reading frame 1
chr17_+_38137115 0.052 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr14_+_105155724 0.051 NM_001031714
NM_022489
NM_032714
INF2


inverted formin, FH2 and WH2 domain containing


chr11_+_20409212 0.051 PRMT3
protein arginine methyltransferase 3
chr1_+_112298515 0.051 DDX20
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
chr15_+_81071708 0.051 NM_018689
KIAA1199
KIAA1199
chr13_+_31774122 0.051 B3GALTL
beta 1,3-galactosyltransferase-like
chr16_+_16326478 0.051 NOMO2
NODAL modulator 2
chr19_-_19754369 0.051 GMIP
GEM interacting protein
chr16_+_67193828 0.051 NM_018378
FBXL8
F-box and leucine-rich repeat protein 8
chr17_-_61523544 0.051 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr12_-_89918531 0.050 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr14_+_23305907 0.050 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr14_+_100259445 0.050 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr12_-_46384346 0.050 SCAF11
SR-related CTD-associated factor 11
chr11_+_119076974 0.050 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr14_-_50319472 0.050 NEMF
nuclear export mediator factor
chr11_+_120110902 0.049 NM_014352
POU2F3
POU class 2 homeobox 3
chr19_-_49496520 0.049 GYS1
glycogen synthase 1 (muscle)
chr5_-_80689948 0.049 NM_130767
ACOT12
acyl-CoA thioesterase 12
chr4_-_7044664 0.049 NM_153376
CCDC96
coiled-coil domain containing 96
chr6_-_139309339 0.049 REPS1
RALBP1 associated Eps domain containing 1
chr4_+_154265841 0.048 MND1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr2_+_153191830 0.048 FMNL2
formin-like 2
chr9_-_35096545 0.048 NM_001201484
NM_032634
NM_152850
PIGO


phosphatidylinositol glycan anchor biosynthesis, class O


chr7_+_72742154 0.048 NM_001135211
NM_003602
FKBP6

FK506 binding protein 6, 36kDa

chr11_-_130786317 0.048 SNX19
sorting nexin 19
chr20_-_42939737 0.048 NM_001080472
FITM2
fat storage-inducing transmembrane protein 2
chr1_-_226595745 0.048 PARP1
poly (ADP-ribose) polymerase 1
chr22_-_36019363 0.048 NM_203377
MB
myoglobin
chr17_-_73901142 0.048 NM_032478
MRPL38
mitochondrial ribosomal protein L38

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 9.15e-05 GO:0044424 intracellular part
1.14 3.00e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 3.77e-03 GO:0005515 protein binding