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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 4.581

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_-_124408665	2.320		ATAD2	ATPase family, AAA domain containing 2
chr8_-_124408458	2.248		ATAD2	ATPase family, AAA domain containing 2
chr8_-_124408688	2.246	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr11_-_19263144	2.237		E2F8	E2F transcription factor 8
chr1_-_36235422	2.234	NM_001190481 NM_022111	CLSPN	claspin
chr8_-_124408669	2.206		ATAD2	ATPase family, AAA domain containing 2
chr11_-_19262424	2.033	NM_024680	E2F8	E2F transcription factor 8
chr20_-_35724330	2.005		RBL1	retinoblastoma-like 1 (p107)
chr1_-_23857711	1.874	NM_004091	E2F2	E2F transcription factor 2
chr13_+_32889594	1.644	NM_000059	BRCA2	breast cancer 2, early onset
chr12_-_77459198	1.588	NM_203394	E2F7	E2F transcription factor 7
chr1_-_23857284	1.584		E2F2	E2F transcription factor 2
chr10_-_73848263	1.575		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr20_-_32274070	1.561		E2F1	E2F transcription factor 1
chr7_+_121513158	1.493	NM_001206838 NM_001206839 NM_002851	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr20_-_35724401	1.449	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr20_-_32274154	1.374	NM_005225	E2F1	E2F transcription factor 1
chr9_-_99180661	1.281	NM_153695	ZNF367	zinc finger protein 367
chr2_+_27498288	1.268	NM_173650	DNAJC5G	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr3_+_10068123	1.250		FANCD2	Fanconi anemia, complementation group D2
chr2_+_17935379	1.230	NM_001130009	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr16_-_3030473	1.228	NM_004203 NM_182687	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr17_+_38444130	1.217		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr17_+_38444134	1.195	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr17_+_29058653	1.195		SUZ12P	suppressor of zeste 12 homolog pseudogene
chr16_-_3030391	1.171		PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr2_+_10262853	1.135	NM_001034	RRM2	ribonucleotide reductase M2
chr17_+_29158948	1.133	NM_024857	ATAD5	ATPase family, AAA domain containing 5
chr10_+_96305521	1.117	NM_018063	HELLS	helicase, lymphoid-specific
chr10_+_13203547	1.094	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr17_+_38444151	1.082		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr1_-_120612301	1.058	NM_001200001 NM_024408	NOTCH2	notch 2
chr13_-_26625164	1.043	NM_001007538	SHISA2	shisa homolog 2 (Xenopus laevis)
chr3_+_10028579	1.034		LOC442075	uncharacterized LOC442075
chr4_+_55523906	1.032	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr2_+_10262694	1.007	NM_001165931	RRM2	ribonucleotide reductase M2
chr12_-_12849120	0.991	NM_006143	GPR19	G protein-coupled receptor 19
chr8_+_121457642	0.970	NM_022045	MTBP	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr7_-_99699030	0.964		MCM7	minichromosome maintenance complex component 7
chr19_+_4909447	0.963	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr3_-_48229800	0.950	NM_001789 NM_201567	CDC25A	cell division cycle 25 homolog A (S. pombe)
chr3_+_10068097	0.946	NM_001018115 NM_033084	FANCD2	Fanconi anemia, complementation group D2
chr7_-_99698993	0.926		MCM7	minichromosome maintenance complex component 7
chr2_+_174219537	0.920	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chr13_+_34392205	0.904	NM_002915 NM_181558	RFC3	replication factor C (activator 1) 3, 38kDa
chr7_-_99698916	0.888		MCM7	minichromosome maintenance complex component 7
chr3_-_48229328	0.887		CDC25A	cell division cycle 25 homolog A (S. pombe)
chr8_-_95907423	0.876	NM_057749	CCNE2	cyclin E2
chr13_-_80915041	0.868	NM_005842	SPRY2	sprouty homolog 2 (Drosophila)
chr5_-_39074478	0.861		RICTOR	RPTOR independent companion of MTOR, complex 2
chr14_-_21572374	0.837
chrX_-_53449548	0.836		SMC1A	structural maintenance of chromosomes 1A
chr22_+_35796104	0.831	NM_006739	MCM5	minichromosome maintenance complex component 5
chr3_+_31574119	0.827		STT3B	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr2_-_27485774	0.827	NM_003459	SLC30A3	solute carrier family 30 (zinc transporter), member 3
chr10_+_62538088	0.824	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr1_-_47779651	0.819	NM_001048166 NM_003035	STIL	SCL/TAL1 interrupting locus
chr1_+_212209129	0.818		DTL	denticleless homolog (Drosophila)
chr15_+_91260575	0.816	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr20_-_5931036	0.802	NM_015939	TRMT6	tRNA methyltransferase 6 homolog (S. cerevisiae)
chr6_+_31126340	0.801		TCF19	transcription factor 19
chr4_+_178231013	0.788		NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr22_+_31031672	0.785	NM_001001479	SLC35E4	solute carrier family 35, member E4
chr7_-_99699426	0.783	NM_005916	MCM7	minichromosome maintenance complex component 7
chrX_-_53449122	0.783		SMC1A	structural maintenance of chromosomes 1A
chr11_+_65029312	0.780	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr4_+_178230979	0.766	NM_018248	NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr3_+_44803280	0.765		KIF15	kinesin family member 15
chr1_+_212208918	0.764	NM_016448	DTL	denticleless homolog (Drosophila)
chr3_+_44803208	0.763	NM_020242	KIF15	kinesin family member 15
chr15_+_32907690	0.762	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr6_+_20402040	0.756	NM_001949	E2F3	E2F transcription factor 3
chr10_+_62538250	0.752		CDK1	cyclin-dependent kinase 1
chr22_+_35796154	0.750		MCM5	minichromosome maintenance complex component 5
chr1_+_212209112	0.749		DTL	denticleless homolog (Drosophila)
chr1_-_120612175	0.741		NOTCH2	notch 2
chr15_+_30918364	0.740		ARHGAP11B	Rho GTPase activating protein 11B
chr9_-_113800980	0.740		LPAR1	lysophosphatidic acid receptor 1
chr11_-_118966175	0.729	NM_002105	H2AFX	H2A histone family, member X
chr14_+_38678594	0.723		SSTR1	somatostatin receptor 1
chr19_+_36545804	0.720		WDR62	WD repeat domain 62
chrX_+_48555124	0.719	NM_003173	SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr2_+_27440233	0.711	NM_004341	CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr6_+_31707724	0.710	NM_002441 NM_025259 NM_172165 NM_172166	MSH5-C6orf26 MSH5	MSH5-C6orf26 readthrough (non-protein coding) mutS homolog 5 (E. coli)
chr13_+_34392254	0.710		RFC3	replication factor C (activator 1) 3, 38kDa
chr1_+_171454636	0.706	NM_015172	PRRC2C	proline-rich coiled-coil 2C
chr15_+_40987326	0.702	NM_001164270 NM_002875 NM_133487 NM_001164269	RAD51	RAD51 homolog (S. cerevisiae)
chr14_-_55658205	0.690	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr22_+_35796294	0.689		MCM5	minichromosome maintenance complex component 5
chr1_+_242011544	0.686		EXO1	exonuclease 1
chr5_+_36876899	0.683		NIPBL	Nipped-B homolog (Drosophila)
chr1_+_242011471	0.682	NM_130398	EXO1	exonuclease 1
chr13_-_110438896	0.679	NM_003749	IRS2	insulin receptor substrate 2
chr2_+_27440342	0.677		CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr12_-_133263899	0.670	NM_006231	POLE	polymerase (DNA directed), epsilon
chr6_+_31126114	0.660	NM_001077511 NM_007109	TCF19	transcription factor 19
chr10_-_129924467	0.659	NM_001145966 NM_002417	MKI67	antigen identified by monoclonal antibody Ki-67
chr11_-_64546201	0.654	NM_004630 NM_201995 NM_201997 NM_201998	SF1	splicing factor 1
chr1_+_86046434	0.650	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr22_-_38966066	0.648	NM_007068	DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr2_-_47168902	0.646	NM_001171508 NM_001171511	MCFD2	multiple coagulation factor deficiency 2
chr5_-_37371078	0.646		NUP155	nucleoporin 155kDa
chr20_+_5931297	0.645	NM_032485 NM_182802	MCM8	minichromosome maintenance complex component 8
chr1_+_179262960	0.645		SOAT1	sterol O-acyltransferase 1
chr5_-_37371182	0.641	NM_153485	NUP155	nucleoporin 155kDa
chr2_-_225907312	0.640	NM_014689	DOCK10	dedicator of cytokinesis 10
chr1_-_120612260	0.638		NOTCH2	notch 2
chr11_+_827584	0.630	NM_173584	EFCAB4A	EF-hand calcium binding domain 4A
chr1_+_179262936	0.629		SOAT1	sterol O-acyltransferase 1
chr1_-_54303933	0.627		TMEM48	transmembrane protein 48
chr5_-_146889618	0.626	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chr5_-_36151953	0.624	NM_001007527	LMBRD2	LMBR1 domain containing 2
chr2_+_17935124	0.624	NM_182625	GEN1	Gen endonuclease homolog 1 (Drosophila)
chrX_+_100353156	0.619		CENPI	centromere protein I
chr12_+_31226799	0.617		DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
chr2_-_232329064	0.617	NM_005381	NCL	nucleolin
chr12_+_31226759	0.610	NM_004399 NM_030653 NM_152438	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
chr1_+_222988324	0.609	NM_032890	DISP1	dispatched homolog 1 (Drosophila)
chr21_-_33104405	0.608	NM_001145444 NM_001145445 NM_020706	SCAF4	SR-related CTD-associated factor 4
chr19_+_36545848	0.606		WDR62	WD repeat domain 62
chr7_-_158497432	0.604	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chr2_+_16080639	0.604	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr6_-_52149472	0.599		MCM3	minichromosome maintenance complex component 3
chr22_+_19467413	0.596	NM_001178010 NM_001178011 NM_003504	CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr1_-_177133818	0.596		ASTN1	astrotactin 1
chr15_+_40987387	0.596		RAD51	RAD51 homolog (S. cerevisiae)
chr1_+_23037329	0.591	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr2_-_232329210	0.591		NCL	nucleolin
chr5_-_37370886	0.586	NM_004298	NUP155	nucleoporin 155kDa
chr6_-_52149541	0.585	NM_002388	MCM3	minichromosome maintenance complex component 3
chr6_-_52149516	0.582		MCM3	minichromosome maintenance complex component 3
chr21_-_33104387	0.581		SCAF4	SR-related CTD-associated factor 4
chr3_-_136471186	0.580	NM_005862	STAG1	stromal antigen 1
chr19_+_45909466	0.578	NM_012099	CD3EAP	CD3e molecule, epsilon associated protein
chr7_+_129074235	0.574	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr6_-_153304093	0.573	NM_012177	FBXO5	F-box protein 5
chr2_-_19558371	0.573	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr15_-_73076025	0.571		ADPGK	ADP-dependent glucokinase
chr1_+_145209067	0.567	NM_203458	NOTCH2NL	notch 2 N-terminal like
chr8_+_94929082	0.567	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr21_-_33104210	0.563		SCAF4	SR-related CTD-associated factor 4
chr1_-_54304107	0.562	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr1_-_177133950	0.558	NM_004319 NM_207108	ASTN1	astrotactin 1
chr12_+_53662000	0.558	NM_012291	ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)
chr19_-_10305600	0.556		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr11_-_77850687	0.553	NM_001007027 NM_024079	ALG8	asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr1_-_225615701	0.552		LBR	lamin B receptor
chr14_+_51706885	0.552	NM_030755	TMX1	thioredoxin-related transmembrane protein 1
chr13_+_33160537	0.541	NM_015032	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr15_+_41851153	0.541	NM_006293	TYRO3	TYRO3 protein tyrosine kinase
chr2_+_36583369	0.535	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr19_+_50094911	0.532	NM_020719	PRR12	proline rich 12
chr8_-_67525426	0.531	NM_001080416 NM_001144755	MYBL1 LOC645895	v-myb myeloblastosis viral oncogene homolog (avian)-like 1 uncharacterized LOC645895
chr11_-_118966103	0.531		H2AFX	H2A histone family, member X
chrX_+_24712063	0.524	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr9_-_35079520	0.523		FANCG	Fanconi anemia, complementation group G
chr1_-_26185847	0.522	NM_024037	C1orf135	chromosome 1 open reading frame 135
chr6_-_132272311	0.521	NM_001901	CTGF	connective tissue growth factor
chr1_-_243418675	0.520	NM_001042404 NM_001042405 NM_014812	CEP170	centrosomal protein 170kDa
chr10_+_73723992	0.516	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr1_-_120612019	0.514		NOTCH2	notch 2
chr15_-_73076057	0.513		ADPGK	ADP-dependent glucokinase
chr19_-_10305536	0.513		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr15_-_73076062	0.512		ADPGK	ADP-dependent glucokinase
chr19_+_4910339	0.512	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chrX_-_153236621	0.506	NM_005334	HCFC1	host cell factor C1 (VP16-accessory protein)
chr22_+_19467467	0.505		CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr8_+_27631902	0.505	NM_001017420	ESCO2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr14_-_50154920	0.504		POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr14_+_85999464	0.502
chr5_-_79950348	0.500		DHFR	dihydrofolate reductase
chr7_-_148581379	0.499		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581297	0.499		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr15_+_41952641	0.499		MGA	MAX gene associated
chr14_-_50155097	0.498	NM_001197330 NM_001197331 NM_002692	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr11_-_108368918	0.497	NM_153705	KDELC2	KDEL (Lys-Asp-Glu-Leu) containing 2
chr12_-_9600763	0.497		DDX11 DDX12P	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
chr16_+_88870185	0.496	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr17_+_80709999	0.496		TBCD	tubulin folding cofactor D
chr7_+_120590816	0.494	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr21_-_30365111	0.493	NM_015565	LTN1	listerin E3 ubiquitin protein ligase 1
chr5_+_175875372	0.493		FAF2	Fas associated factor family member 2
chr8_+_26435590	0.491		DPYSL2	dihydropyrimidinase-like 2
chr11_-_64851449	0.489		CDCA5	cell division cycle associated 5
chr9_-_35079751	0.488	NM_004629	FANCG	Fanconi anemia, complementation group G
chr1_+_156052330	0.487		LMNA	lamin A/C
chr19_-_50432731	0.487		NUP62	nucleoporin 62kDa
chr12_+_27933162	0.487	NM_020782	KLHDC5	kelch domain containing 5
chr1_+_62902708	0.485		USP1	ubiquitin specific peptidase 1
chr15_-_73076071	0.483		ADPGK	ADP-dependent glucokinase
chr15_+_41221530	0.481	NM_019074	DLL4	delta-like 4 (Drosophila)
chr3_-_160822625	0.478	NM_033169 NM_001038628 NM_003781 NM_033167 NM_033168	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_100598705	0.477	NM_019083	CCDC76	coiled-coil domain containing 76
chr2_-_47168870	0.475		MCFD2	multiple coagulation factor deficiency 2
chr16_+_2510080	0.470	NM_025108	C16orf59	chromosome 16 open reading frame 59
chr2_+_219575507	0.468	NM_014640	TTLL4	tubulin tyrosine ligase-like family, member 4
chr16_+_67596309	0.466	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr11_-_62623212	0.463		SNHG1	small nucleolar RNA host gene 1 (non-protein coding)
chr5_-_79950307	0.463		DHFR	dihydrofolate reductase
chr12_+_53645869	0.462	NM_032889	MFSD5	major facilitator superfamily domain containing 5

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.56	5.38e-31	GO:0007049	cell cycle
2.92	2.67e-29	GO:0022403	cell cycle phase
2.67	3.86e-27	GO:0022402	cell cycle process
1.88	1.47e-25	GO:0090304	nucleic acid metabolic process
1.75	8.78e-25	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.84	1.43e-22	GO:0000278	mitotic cell cycle
1.51	1.74e-21	GO:0044260	cellular macromolecule metabolic process
2.70	9.39e-21	GO:0051276	chromosome organization
2.69	1.15e-19	GO:0006259	DNA metabolic process
4.20	1.46e-18	GO:0006260	DNA replication
1.59	5.85e-18	GO:0034641	cellular nitrogen compound metabolic process
1.57	2.41e-17	GO:0006807	nitrogen compound metabolic process
3.23	2.21e-16	GO:0051325	interphase
2.82	3.16e-16	GO:0000279	M phase
2.94	4.45e-16	GO:0006397	mRNA processing
2.59	1.01e-15	GO:0016071	mRNA metabolic process
1.40	2.51e-15	GO:0043170	macromolecule metabolic process
3.15	5.38e-15	GO:0051329	interphase of mitotic cell cycle
2.39	9.22e-15	GO:0006396	RNA processing
3.12	9.99e-15	GO:0008380	RNA splicing
3.61	4.12e-14	GO:0000375	RNA splicing, via transesterification reactions
1.78	1.62e-13	GO:0006996	organelle organization
1.48	3.88e-13	GO:0071840	cellular component organization or biogenesis
1.49	6.34e-13	GO:0016043	cellular component organization
1.16	6.74e-13	GO:0009987	cellular process
2.82	1.11e-12	GO:0010564	regulation of cell cycle process
3.50	1.26e-12	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.50	1.26e-12	GO:0000398	nuclear mRNA splicing, via spliceosome
1.55	1.34e-12	GO:0071841	cellular component organization or biogenesis at cellular level
2.28	5.18e-12	GO:0051726	regulation of cell cycle
1.54	1.27e-11	GO:0071842	cellular component organization at cellular level
1.29	2.24e-11	GO:0044237	cellular metabolic process
5.25	3.72e-11	GO:0006261	DNA-dependent DNA replication
1.28	1.31e-10	GO:0044238	primary metabolic process
2.34	1.39e-10	GO:0006974	response to DNA damage stimulus
2.83	1.82e-10	GO:0000280	nuclear division
2.83	1.82e-10	GO:0007067	mitosis
2.63	6.91e-10	GO:0006281	DNA repair
2.75	7.08e-10	GO:0000087	M phase of mitotic cell cycle
2.74	8.36e-10	GO:0048285	organelle fission
3.66	1.27e-09	GO:0006310	DNA recombination
3.55	3.54e-09	GO:0000082	G1/S transition of mitotic cell cycle
7.69	4.09e-09	GO:0006271	DNA strand elongation involved in DNA replication
1.62	7.47e-09	GO:0016070	RNA metabolic process
7.17	1.95e-08	GO:0022616	DNA strand elongation
8.86	2.25e-08	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
3.80	2.52e-08	GO:0051320	S phase
2.24	4.82e-08	GO:0006325	chromatin organization
3.75	7.46e-08	GO:0000084	S phase of mitotic cell cycle
2.81	1.81e-07	GO:0071156	regulation of cell cycle arrest
2.37	2.36e-07	GO:0016568	chromatin modification
3.69	4.93e-07	GO:0007059	chromosome segregation
2.79	5.45e-07	GO:0000075	cell cycle checkpoint
1.53	7.28e-07	GO:0010467	gene expression
1.21	1.61e-06	GO:0008152	metabolic process
3.52	1.76e-06	GO:0051028	mRNA transport
3.45	2.86e-06	GO:0051321	meiotic cell cycle
1.80	3.79e-06	GO:0033554	cellular response to stress
3.33	4.15e-06	GO:0050657	nucleic acid transport
3.33	4.15e-06	GO:0050658	RNA transport
3.33	4.15e-06	GO:0051236	establishment of RNA localization
2.28	4.36e-06	GO:0051301	cell division
2.99	7.97e-06	GO:0071103	DNA conformation change
1.53	8.75e-06	GO:0034645	cellular macromolecule biosynthetic process
3.22	9.99e-06	GO:0006403	RNA localization
3.37	1.01e-05	GO:0007126	meiosis
3.37	1.01e-05	GO:0051327	M phase of meiotic cell cycle
4.72	1.12e-05	GO:0051053	negative regulation of DNA metabolic process
4.22	1.78e-05	GO:0031124	mRNA 3'-end processing
1.51	2.17e-05	GO:0009059	macromolecule biosynthetic process
7.74	3.57e-05	GO:0007062	sister chromatid cohesion
6.91	4.53e-05	GO:0006270	DNA-dependent DNA replication initiation
1.61	4.87e-05	GO:0044085	cellular component biogenesis
2.96	5.15e-05	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
9.49	5.38e-05	GO:0071897	DNA biosynthetic process
6.61	8.80e-05	GO:0090329	regulation of DNA-dependent DNA replication
2.99	1.08e-04	GO:0006323	DNA packaging
3.71	1.11e-04	GO:0031123	RNA 3'-end processing
1.85	1.13e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
6.96	1.62e-04	GO:2000104	negative regulation of DNA-dependent DNA replication
4.08	1.75e-04	GO:0006406	mRNA export from nucleus
5.00	1.93e-04	GO:0008156	negative regulation of DNA replication
1.83	1.97e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.67	2.29e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.67	2.41e-04	GO:0031324	negative regulation of cellular metabolic process
1.82	2.68e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
4.60	2.77e-04	GO:0000819	sister chromatid segregation
1.63	3.43e-04	GO:0009892	negative regulation of metabolic process
1.77	3.59e-04	GO:0031327	negative regulation of cellular biosynthetic process
3.48	3.96e-04	GO:0006275	regulation of DNA replication
4.63	6.32e-04	GO:0000070	mitotic sister chromatid segregation
1.74	7.02e-04	GO:0065003	macromolecular complex assembly
1.59	7.18e-04	GO:0022607	cellular component assembly
1.61	7.36e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.36	8.65e-04	GO:0044249	cellular biosynthetic process
1.73	8.99e-04	GO:0009890	negative regulation of biosynthetic process
3.41	1.11e-03	GO:0000216	M/G1 transition of mitotic cell cycle
6.66	1.14e-03	GO:0032201	telomere maintenance via semi-conservative replication
2.94	1.22e-03	GO:0071824	protein-DNA complex subunit organization
3.64	1.27e-03	GO:0006405	RNA export from nucleus
2.99	1.46e-03	GO:0065004	protein-DNA complex assembly
3.47	1.54e-03	GO:0006338	chromatin remodeling
2.72	1.56e-03	GO:0006333	chromatin assembly or disassembly
1.74	1.79e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
5.80	1.79e-03	GO:0031055	chromatin remodeling at centromere
1.35	1.92e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
7.12	2.09e-03	GO:0006297	nucleotide-excision repair, DNA gap filling
3.54	2.10e-03	GO:0006473	protein acetylation
6.33	2.12e-03	GO:0000722	telomere maintenance via recombination
1.27	2.26e-03	GO:0031323	regulation of cellular metabolic process
2.66	2.53e-03	GO:0051052	regulation of DNA metabolic process
3.24	2.75e-03	GO:0051168	nuclear export
2.46	3.12e-03	GO:0006913	nucleocytoplasmic transport
2.58	3.17e-03	GO:0000226	microtubule cytoskeleton organization
3.00	3.71e-03	GO:0031497	chromatin assembly
3.71	3.80e-03	GO:0016573	histone acetylation
2.43	4.10e-03	GO:0051169	nuclear transport
1.27	4.65e-03	GO:0060255	regulation of macromolecule metabolic process
5.36	4.78e-03	GO:0006312	mitotic recombination
3.65	4.95e-03	GO:0018393	internal peptidyl-lysine acetylation
3.59	6.40e-03	GO:0018394	peptidyl-lysine acetylation
3.96	6.41e-03	GO:0000723	telomere maintenance
1.95	6.41e-03	GO:0034622	cellular macromolecular complex assembly
4.45	6.82e-03	GO:0051318	G1 phase
1.32	7.65e-03	GO:0009058	biosynthetic process
1.30	7.85e-03	GO:0051171	regulation of nitrogen compound metabolic process
3.53	8.22e-03	GO:0006475	internal protein amino acid acetylation
3.88	8.57e-03	GO:0007051	spindle organization
3.88	8.57e-03	GO:0032200	telomere organization
1.24	9.09e-03	GO:0019222	regulation of metabolic process
1.32	9.53e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.31	9.54e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	9.54e-03	GO:0031326	regulation of cellular biosynthetic process
3.26	1.50e-02	GO:0006302	double-strand break repair
9.49	1.51e-02	GO:0000731	DNA synthesis involved in DNA repair
9.49	1.51e-02	GO:0007064	mitotic sister chromatid cohesion
1.30	1.56e-02	GO:0009889	regulation of biosynthetic process
1.15	1.92e-02	GO:0050794	regulation of cellular process
5.70	2.29e-02	GO:0006298	mismatch repair
3.05	2.39e-02	GO:0043543	protein acylation
2.73	3.22e-02	GO:0034728	nucleosome organization
1.24	3.25e-02	GO:0080090	regulation of primary metabolic process
1.59	3.30e-02	GO:0071844	cellular component assembly at cellular level
3.92	3.36e-02	GO:0006369	termination of RNA polymerase II transcription
5.43	3.73e-02	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus
5.43	3.73e-02	GO:0016444	somatic cell DNA recombination
1.14	4.96e-02	GO:0050789	regulation of biological process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.27	2.37e-53	GO:0044428	nuclear part
2.34	1.61e-48	GO:0031981	nuclear lumen
2.12	5.75e-44	GO:0070013	intracellular organelle lumen
1.59	8.17e-44	GO:0005634	nucleus
1.33	8.30e-43	GO:0043226	organelle
2.09	8.46e-43	GO:0043233	organelle lumen
2.07	1.95e-42	GO:0031974	membrane-enclosed lumen
1.33	4.01e-42	GO:0043229	intracellular organelle
2.51	3.34e-41	GO:0005654	nucleoplasm
1.36	1.34e-39	GO:0043227	membrane-bounded organelle
1.36	3.83e-39	GO:0043231	intracellular membrane-bounded organelle
1.55	5.35e-38	GO:0044446	intracellular organelle part
1.54	1.84e-37	GO:0044422	organelle part
1.24	3.51e-33	GO:0044424	intracellular part
1.22	1.96e-31	GO:0005622	intracellular
2.75	2.83e-21	GO:0005694	chromosome
2.32	1.70e-16	GO:0044451	nucleoplasm part
2.62	3.53e-15	GO:0044427	chromosomal part
3.38	9.95e-14	GO:0000228	nuclear chromosome
1.53	3.96e-13	GO:0043228	non-membrane-bounded organelle
1.53	3.96e-13	GO:0043232	intracellular non-membrane-bounded organelle
1.43	8.43e-12	GO:0032991	macromolecular complex
3.35	1.19e-10	GO:0044454	nuclear chromosome part
1.07	1.27e-08	GO:0044464	cell part
1.07	1.33e-08	GO:0005623	cell
2.70	5.66e-08	GO:0000785	chromatin
1.38	4.33e-07	GO:0043234	protein complex
5.47	2.61e-06	GO:0005657	replication fork
11.25	5.78e-06	GO:0035098	ESC/E(Z) complex
7.74	6.37e-06	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
7.33	1.40e-05	GO:0031519	PcG protein complex
2.93	1.93e-05	GO:0005681	spliceosomal complex
2.43	2.95e-05	GO:0016604	nuclear body
1.91	3.74e-05	GO:0005730	nucleolus
1.89	4.39e-05	GO:0030529	ribonucleoprotein complex
2.82	4.73e-05	GO:0000793	condensed chromosome
11.08	6.53e-05	GO:0042555	MCM complex
2.07	1.46e-04	GO:0005815	microtubule organizing center
2.48	2.24e-04	GO:0005819	spindle
3.37	2.51e-04	GO:0071013	catalytic step 2 spliceosome
1.71	2.77e-04	GO:0015630	microtubule cytoskeleton
3.24	4.91e-04	GO:0000790	nuclear chromatin
3.82	8.91e-04	GO:0034708	methyltransferase complex
3.82	8.91e-04	GO:0035097	histone methyltransferase complex
3.45	1.07e-03	GO:0000922	spindle pole
3.59	1.14e-03	GO:0000123	histone acetyltransferase complex
4.03	1.94e-03	GO:0000792	heterochromatin
1.39	3.85e-03	GO:0012505	endomembrane system
2.14	4.03e-03	GO:0005813	centrosome
2.41	7.48e-03	GO:0000775	chromosome, centromeric region
5.96	8.76e-03	GO:0030894	replisome
5.96	8.76e-03	GO:0043601	nuclear replisome
5.18	1.05e-02	GO:0043596	nuclear replication fork
2.98	2.84e-02	GO:0034399	nuclear periphery
2.64	3.52e-02	GO:0016585	chromatin remodeling complex
1.94	4.48e-02	GO:0005635	nuclear envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.54	1.52e-17	GO:0003676	nucleic acid binding
1.30	2.62e-17	GO:0005515	protein binding
1.58	1.77e-12	GO:0000166	nucleotide binding
1.14	4.93e-12	GO:0005488	binding
1.51	8.54e-10	GO:0003677	DNA binding
1.89	1.10e-08	GO:0003723	RNA binding
2.66	1.04e-05	GO:0003682	chromatin binding
4.02	2.77e-05	GO:0008094	DNA-dependent ATPase activity
1.39	6.32e-04	GO:0017076	purine nucleotide binding
2.40	7.51e-04	GO:0043566	structure-specific DNA binding
3.78	7.72e-04	GO:0003697	single-stranded DNA binding
1.38	9.96e-04	GO:0032553	ribonucleotide binding
1.38	9.96e-04	GO:0032555	purine ribonucleotide binding
1.38	1.15e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.42	1.84e-03	GO:0030554	adenyl nucleotide binding
1.42	2.06e-03	GO:0032559	adenyl ribonucleotide binding
1.41	3.12e-03	GO:0005524	ATP binding
1.57	7.22e-03	GO:0016462	pyrophosphatase activity
1.56	8.47e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.57	8.66e-03	GO:0017111	nucleoside-triphosphatase activity
1.56	9.94e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
6.33	2.73e-02	GO:0030983	mismatched DNA binding
1.52	4.76e-02	GO:0019899	enzyme binding