Motif ID: EBF1.p2

Z-value: 1.865


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EBF1chr5_-_158526698-0.648.6e-02Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_69924407 4.493 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr16_+_22825481 3.789 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_+_2005424 3.500 NM_001242874
PRKCZ
protein kinase C, zeta
chr3_-_69435429 2.791 NM_015123
FRMD4B
FERM domain containing 4B
chr16_+_68679198 2.646 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr15_+_41136178 2.617 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr14_+_61788398 2.576 NM_006255
PRKCH
protein kinase C, eta
chr19_-_51456159 2.490 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr18_-_28681885 2.294 NM_004949
NM_024422
DSC2

desmocollin 2

chr16_+_22825806 2.216 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr8_+_82644663 2.196 NM_152284
CHMP4C
charged multivesicular body protein 4C
chr7_+_26331493 2.169 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr19_-_51522953 2.095 NM_145888
KLK10
kallikrein-related peptidase 10
chr13_-_20805371 2.085 NM_006783
GJB6
gap junction protein, beta 6, 30kDa
chr17_+_9548853 2.048 NM_153210
USP43
ubiquitin specific peptidase 43
chr1_-_21059132 1.995 NM_001103160
NM_001103161
SH2D5

SH2 domain containing 5

chr22_+_45098091 1.991 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr2_-_110874142 1.915 NM_005434
MALL
mal, T-cell differentiation protein-like
chr8_-_57233240 1.875 NM_138969
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr1_+_109792640 1.809 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr16_+_68679229 1.800 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr1_+_2005083 1.715 NM_001033581
PRKCZ
protein kinase C, zeta
chr19_-_51523272 1.699 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr8_-_57232700 1.672 SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr19_+_7702020 1.659 STXBP2
syntaxin binding protein 2
chr7_+_26331611 1.638 SNX10
sorting nexin 10
chr14_-_105635114 1.569 NM_002226
NM_145159
JAG2

jagged 2

chr15_-_79237320 1.556 CTSH
cathepsin H
chr15_-_79237353 1.523 NM_004390
CTSH
cathepsin H
chr8_-_127570710 1.514 NM_174911
FAM84B
family with sequence similarity 84, member B
chr6_+_54711568 1.510 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr19_-_51487070 1.495 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr2_-_110873638 1.407 MALL
mal, T-cell differentiation protein-like
chr12_-_6484904 1.400 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr3_-_57113292 1.361 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr8_-_144654921 1.357 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr11_-_72504643 1.327 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr14_-_94844881 1.326 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_+_234349995 1.325 SLC35F3
solute carrier family 35, member F3
chr1_+_234040547 1.307 NM_173508
SLC35F3
solute carrier family 35, member F3
chr11_+_1861431 1.278 NM_001145841
TNNI2
troponin I type 2 (skeletal, fast)
chr12_-_6486522 1.257 NM_001159575
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr10_+_82168206 1.234 NM_001243780
NM_001243781
NM_032333
C10orf58


chromosome 10 open reading frame 58


chr2_-_46384 1.215 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr5_-_141257943 1.206 NM_002587
NM_032420
PCDH1

protocadherin 1

chr11_+_1860232 1.196 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr15_+_90744506 1.153 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr2_-_31361591 1.153 NM_001253826
NM_024572
GALNT14

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)

chr19_-_6767417 1.145 NM_005490
SH2D3A
SH2 domain containing 3A
chr14_+_67999915 1.123 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr19_+_35739519 1.122 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr1_+_43735664 1.112 NM_144626
TMEM125
transmembrane protein 125
chr1_+_1981902 1.108 NM_002744
PRKCZ
protein kinase C, zeta
chr1_+_15256295 1.090 NM_001018001
KAZN
kazrin, periplakin interacting protein
chrX_-_102565805 1.089 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr16_+_57406398 1.064 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr22_+_45064323 1.062 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr22_+_45098046 1.060 NM_181333
PRR5
proline rich 5 (renal)
chr19_+_35739778 1.036 LSR
lipolysis stimulated lipoprotein receptor
chr1_+_233463513 1.026 NM_032435
KIAA1804
mixed lineage kinase 4
chr18_+_11751470 1.022 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr1_-_1051458 1.013 C1orf159
chromosome 1 open reading frame 159
chr18_+_55711890 0.982 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr2_+_131674223 0.964 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr15_+_90728118 0.955 NM_020210
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr16_-_68269948 0.949 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr1_+_15272414 0.943 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr14_+_65171243 0.943 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_+_206547131 0.930 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr14_-_94849552 0.929 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr20_-_62284701 0.921 NM_015894
STMN3
stathmin-like 3
chr19_-_39264144 0.921 NM_002307
LGALS7
LGALS7B
lectin, galactoside-binding, soluble, 7
lectin, galactoside-binding, soluble, 7B
chr2_+_102608305 0.921 NM_004633
IL1R2
interleukin 1 receptor, type II
chr2_+_97426571 0.909 NM_020184
CNNM4
cyclin M4
chr16_+_3115641 0.901 NM_001012632
NM_001012636
IL32

interleukin 32

chrX_+_105969875 0.893 NM_194463
RNF128
ring finger protein 128
chr3_-_69435223 0.887 FRMD4B
FERM domain containing 4B
chr10_+_82167584 0.878 NM_001243779
C10orf58
chromosome 10 open reading frame 58
chr19_-_291335 0.877 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr2_+_206547352 0.854 NRP2
neuropilin 2
chr15_-_63674074 0.849 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr4_+_1795004 0.845 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr12_+_20848288 0.842 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr10_-_116164514 0.842 NM_001001936
NM_032550
AFAP1L2

actin filament associated protein 1-like 2

chr8_-_145582111 0.836 NM_012162
NM_024555
FBXL6

F-box and leucine-rich repeat protein 6

chr8_-_127570465 0.821 FAM84B
family with sequence similarity 84, member B
chr18_+_55711746 0.812 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr10_-_14646237 0.810 FAM107B
family with sequence similarity 107, member B
chr20_+_58296264 0.805 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr11_+_1860718 0.801 NM_001145829
TNNI2
troponin I type 2 (skeletal, fast)
chr14_+_75745480 0.800 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr17_-_73874634 0.798 NM_033452
TRIM47
tripartite motif containing 47
chr2_+_223289212 0.793 SGPP2
sphingosine-1-phosphate phosphatase 2
chr18_+_55711388 0.785 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chrX_-_119445306 0.775 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr7_-_994259 0.760 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr15_-_63673918 0.756 CA12
carbonic anhydrase XII
chr9_-_117150217 0.756 AKNA
AT-hook transcription factor
chr9_-_124984018 0.750 NM_001242335
LHX6
LIM homeobox 6
chr6_+_13925097 0.743 NM_001165032
NM_152737
RNF182

ring finger protein 182

chr6_+_13924676 0.742 NM_001165034
RNF182
ring finger protein 182
chr14_+_68086633 0.738 ARG2
arginase, type II
chr6_+_90276556 0.734 NM_001242814
ANKRD6
ankyrin repeat domain 6
chr1_-_24513737 0.732 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr19_-_55660557 0.730 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr15_+_45422130 0.720 NM_017434
NM_175940
DUOX1

dual oxidase 1

chr19_-_36001336 0.708 NM_001126059
DMKN
dermokine
chr20_+_58630965 0.691 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr19_+_35739838 0.688 LSR
lipolysis stimulated lipoprotein receptor
chr22_+_45072687 0.688 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr1_+_27668462 0.683 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr1_+_15479298 0.679 TMEM51
transmembrane protein 51
chr11_-_87908551 0.677 NM_022337
RAB38
RAB38, member RAS oncogene family
chr7_-_75988315 0.677 NM_012479
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr4_-_90758126 0.675 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr15_+_41136622 0.664 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr10_-_14646407 0.663 FAM107B
family with sequence similarity 107, member B
chr20_-_50808174 0.663 ZFP64
zinc finger protein 64 homolog (mouse)
chr14_-_51135021 0.660 NM_021818
SAV1
salvador homolog 1 (Drosophila)
chr12_-_53298765 0.655 NM_002273
KRT8
keratin 8
chr16_-_85784628 0.655 NM_206967
C16orf74
chromosome 16 open reading frame 74
chr7_+_128577990 0.653 NM_001098629
NM_001098630
NM_001242452
IRF5


interferon regulatory factor 5


chr9_-_124989755 0.643 NM_001242334
LHX6
LIM homeobox 6
chr1_-_12677347 0.640 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr5_+_65892139 0.639 NM_001164664
NM_198828
MAST4

microtubule associated serine/threonine kinase family member 4

chr19_-_51327003 0.631 NM_002257
KLK1
kallikrein 1
chr19_-_6720585 0.628 NM_000064
C3
complement component 3
chr11_+_722282 0.623 EPS8L2
EPS8-like 2
chr4_+_89299874 0.621 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr11_-_117747331 0.612 FXYD6
FXYD domain containing ion transport regulator 6
chr8_-_145641828 0.610 NM_017767
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr16_-_75529289 0.609


chr4_-_84255999 0.609 HPSE
heparanase
chr2_+_173292306 0.607 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr16_-_71264557 0.591 NM_032821
NM_017558
HYDIN

hydrocephalus inducing homolog (mouse)

chr15_+_69606741 0.590 NM_001104554
PAQR5
progestin and adipoQ receptor family member V
chr16_+_71660063 0.576 NM_001017967
NM_052858
MARVELD3

MARVEL domain containing 3

chr19_+_55591759 0.575 NM_017729
EPS8L1
EPS8-like 1
chr19_+_1524072 0.575 NM_001243079
PLK5
polo-like kinase 5
chr8_-_144947433 0.571 NM_031308
EPPK1
epiplakin 1
chr17_-_74497406 0.570 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr1_+_27668499 0.569 SYTL1
synaptotagmin-like 1
chr10_+_24498088 0.565 KIAA1217
KIAA1217
chr6_+_71123147 0.562 FAM135A
family with sequence similarity 135, member A
chr22_+_23229959 0.562 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr19_-_2042022 0.559 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr10_-_88730928 0.558 LOC100133190
uncharacterized LOC100133190
chr18_+_61420276 0.554 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr17_+_73720775 0.547 NM_001005619
ITGB4
integrin, beta 4
chr4_-_4291731 0.546 NM_001145725
LYAR
Ly1 antibody reactive homolog (mouse)
chr14_+_24867926 0.542 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr21_+_46825291 0.541


chr5_+_149109814 0.541 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr8_-_33424642 0.540 NM_024787
RNF122
ring finger protein 122
chr11_-_118016134 0.540 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr20_+_21106718 0.539 PLK1S1
polo-like kinase 1 substrate 1
chr11_-_117747618 0.538 NM_001204268
NM_001243598
NM_001164832
NM_001164836
NM_001164837
NM_022003
FXYD6-FXYD2

FXYD6



FXYD6-FXYD2 readthrough

FXYD domain containing ion transport regulator 6



chr5_+_148206155 0.537 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr10_+_24497719 0.533 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr8_-_125579395 0.532 MTSS1
metastasis suppressor 1
chr14_-_67878859 0.531 PLEK2
pleckstrin 2
chr17_-_39942937 0.530 NM_002230
NM_021991
JUP

junction plakoglobin

chr19_-_14260728 0.530 LPHN1
latrophilin 1
chr11_+_60691911 0.528 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr19_-_41933255 0.523


chr19_+_45843997 0.521 NM_177417
KLC3
kinesin light chain 3
chr20_-_1309809 0.521 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr10_-_88717319 0.514 NM_024756
MMRN2
multimerin 2
chr11_-_11643542 0.513 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr8_+_22436253 0.513 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr12_+_2904101 0.513 NM_002014
FKBP4
FK506 binding protein 4, 59kDa
chr2_+_220325533 0.512 NM_001173476
SPEG
SPEG complex locus
chr21_-_43187197 0.512 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr17_-_74581934 0.512 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr1_+_117452359 0.511 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr17_+_37894212 0.510 GRB7
growth factor receptor-bound protein 7
chr14_-_67878770 0.508 NM_016445
PLEK2
pleckstrin 2
chr2_-_70994846 0.507 NM_001185054
ADD2
adducin 2 (beta)
chr11_-_66488712 0.505 NM_006946
SPTBN2
spectrin, beta, non-erythrocytic 2
chr11_+_59522905 0.490 STX3
syntaxin 3
chr11_+_62623466 0.490 NM_001012662
NM_001012664
NM_002394
SLC3A2


solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2


chr19_+_17862285 0.490 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr4_-_57687827 0.486 NM_021114
SPINK2
serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
chr14_+_65171149 0.486 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr20_-_44540685 0.484 PLTP
phospholipid transfer protein
chr19_-_55881740 0.480 NM_000641
IL11
interleukin 11
chr14_+_68086655 0.479 ARG2
arginase, type II
chr8_-_125740650 0.476 NM_014751
MTSS1
metastasis suppressor 1
chr10_+_11865310 0.475 NM_153256
C10orf47
chromosome 10 open reading frame 47
chr20_+_58515408 0.473 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr4_-_84255895 0.471 NM_001199830
HPSE
heparanase
chr3_-_196756682 0.471 NM_033316
NM_005929
MFI2

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

chr6_+_71123105 0.471 NM_001105531
NM_020819
FAM135A

family with sequence similarity 135, member A

chr9_-_117160748 0.470 AKNA
AT-hook transcription factor
chr7_+_128578246 0.469 NM_032643
IRF5
interferon regulatory factor 5
chr19_+_3185965 0.468 NCLN
nicalin
chr19_+_56989549 0.467 LOC100128252
uncharacterized LOC100128252
chr19_+_46733008 0.464 NM_198541
IGFL1
IGF-like family member 1
chr20_-_50808523 0.458 NM_018197
NM_022088
NM_199426
NM_199427
ZFP64



zinc finger protein 64 homolog (mouse)



chr9_-_133814422 0.453 NM_001145106
FIBCD1
fibrinogen C domain containing 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 4.95e-05 GO:0044459 plasma membrane part
1.13 1.61e-04 GO:0016020 membrane
2.04 4.69e-04 GO:0005911 cell-cell junction
1.15 3.10e-03 GO:0031224 intrinsic to membrane
1.15 3.69e-03 GO:0016021 integral to membrane
1.13 6.75e-03 GO:0044425 membrane part
1.49 1.46e-02 GO:0030054 cell junction
1.31 3.47e-02 GO:0031226 intrinsic to plasma membrane
1.33 4.04e-02 GO:0000267 cell fraction
1.30 4.92e-02 GO:0005887 integral to plasma membrane

Nothing significant found in function category.