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• Activity deltas table
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Motif ID: ELF1,2,4.p2

Z-value: 1.292

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr21_+_43823970	0.386	NM_001001895 NM_001243467 NM_018961	UBASH3A	ubiquitin associated and SH3 domain containing A
chr1_-_52870058	0.341	NM_001190818 NM_001190819 NM_004153	ORC1	origin recognition complex, subunit 1
chr5_+_140044383	0.338	NM_017706	WDR55	WD repeat domain 55
chr14_+_29236882	0.335		FOXG1	forkhead box G1
chr5_+_140044457	0.320		WDR55	WD repeat domain 55
chr2_-_54198055	0.317
chr22_-_19512859	0.302	NM_001130861 NM_003277	CLDN5	claudin 5
chr2_+_65454828	0.302	NM_001005386 NM_005722	ACTR2	ARP2 actin-related protein 2 homolog (yeast)
chr12_-_124068864	0.300
chr11_-_62389571	0.293	NM_012200	B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr11_-_62389376	0.263		B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr16_-_89349696	0.262		ANKRD11	ankyrin repeat domain 11
chr19_-_56632644	0.252	NM_001002836	ZNF787	zinc finger protein 787
chr10_+_26986557	0.246	NM_014317	PDSS1	prenyl (decaprenyl) diphosphate synthase, subunit 1
chr12_+_133287382	0.235	NM_001170543 NM_001170544 NM_138575	PGAM5	phosphoglycerate mutase family member 5
chr6_-_11382501	0.233	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr17_-_42264075	0.231	NM_178542	C17orf65	chromosome 17 open reading frame 65
chr15_-_50647349	0.227		GABPB1	GA binding protein transcription factor, beta subunit 1
chr20_-_34287043	0.223	NM_001198989 NM_021100	NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)
chr5_+_892950	0.222	NM_001166260 NM_004237	TRIP13	thyroid hormone receptor interactor 13
chr9_+_131218402	0.222		ODF2	outer dense fiber of sperm tails 2
chr13_-_60737899	0.220		DIAPH3	diaphanous homolog 3 (Drosophila)
chr1_+_43855599	0.219		SZT2	seizure threshold 2 homolog (mouse)
chr10_-_43892697	0.218	NM_001098207	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr17_-_42264023	0.214		C17orf65	chromosome 17 open reading frame 65
chr15_-_50647275	0.213		GABPB1	GA binding protein transcription factor, beta subunit 1
chr4_+_100871625	0.212		LOC256880	uncharacterized LOC256880
chr5_-_64777703	0.211	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr2_+_101869350	0.211		C2orf29	chromosome 2 open reading frame 29
chr12_-_56320895	0.206	NM_001143853	WIBG	within bgcn homolog (Drosophila)
chr20_-_5931036	0.206	NM_015939	TRMT6	tRNA methyltransferase 6 homolog (S. cerevisiae)
chr11_-_46722139	0.205		ARHGAP1	Rho GTPase activating protein 1
chr21_-_34185943	0.204	NM_001162495 NM_001162496 NM_019596	C21orf62	chromosome 21 open reading frame 62
chr15_-_50647385	0.203		GABPB1	GA binding protein transcription factor, beta subunit 1
chr13_-_99229037	0.203		STK24	serine/threonine kinase 24
chr10_-_99160987	0.201		RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)
chr1_+_162467622	0.201		UHMK1	U2AF homology motif (UHM) kinase 1
chr2_+_101869327	0.200	NM_017546	C2orf29	chromosome 2 open reading frame 29
chr16_+_2732475	0.199	NM_018992	KCTD5	potassium channel tetramerisation domain containing 5
chr1_-_28969516	0.198	NM_001135218 NM_005644	TAF12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr7_+_44084317	0.195		DBNL	drebrin-like
chr10_-_99161013	0.195	NM_001145114 NM_015179	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)
chr16_+_2732526	0.195		KCTD5	potassium channel tetramerisation domain containing 5
chr5_-_122759003	0.194	NM_001166226 NM_153223	CEP120	centrosomal protein 120kDa
chr16_+_77225094	0.194		MON1B	MON1 homolog B (yeast)
chr15_+_38544119	0.192		SPRED1	sprouty-related, EVH1 domain containing 1
chr19_+_52901101	0.192	NM_032423	ZNF528	zinc finger protein 528
chr13_-_31191509	0.192		HMGB1	high mobility group box 1
chr4_+_153701113	0.190		ARFIP1	ADP-ribosylation factor interacting protein 1
chr3_-_108308221	0.190		KIAA1524	KIAA1524
chr17_+_19030781	0.190	NM_001129778	GRAPL	GRB2-related adaptor protein-like
chr9_+_131218435	0.188		ODF2	outer dense fiber of sperm tails 2
chr8_-_28347733	0.188	NM_172366	FBXO16 ZNF395	F-box protein 16 zinc finger protein 395
chrX_+_21958714	0.186	NM_004595	SMS	spermine synthase
chr5_+_82373316	0.186	NM_003401 NM_022406 NM_022550	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4
chr1_-_111506494	0.185	NM_001006945 NM_018372	LRIF1	ligand dependent nuclear receptor interacting factor 1
chr1_+_38261079	0.184	NM_152496	MANEAL	mannosidase, endo-alpha-like
chr10_+_27443752	0.183	NM_001172303 NM_001172304 NM_032844	MASTL	microtubule associated serine/threonine kinase-like
chr1_+_169337432	0.181		BLZF1	basic leucine zipper nuclear factor 1
chr5_+_34915781	0.180	NM_018321	BRIX1	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr10_+_45496272	0.180	NM_006963	ZNF22	zinc finger protein 22 (KOX 15)
chr9_-_88969256	0.180		ZCCHC6	zinc finger, CCHC domain containing 6
chr7_+_44084306	0.179		DBNL	drebrin-like
chr22_-_17747520	0.179		CECR3	cat eye syndrome chromosome region, candidate 3 (non-protein coding)
chr19_-_4723814	0.178	NM_139159	DPP9	dipeptidyl-peptidase 9
chr9_-_112083196	0.178		EPB41L4B	erythrocyte membrane protein band 4.1 like 4B
chr15_+_74753602	0.178		LOC440288	uncharacterized LOC440288
chrX_-_15872905	0.178
chr1_-_31230673	0.178	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr12_-_52604488	0.177	NM_001242696	LOC283403	uncharacterized LOC283403
chr5_-_171433605	0.176		FBXW11	F-box and WD repeat domain containing 11
chr9_+_131218426	0.176		ODF2	outer dense fiber of sperm tails 2
chr12_+_7079943	0.175	NM_006331	EMG1	EMG1 nucleolar protein homolog (S. cerevisiae)
chr20_+_49575347	0.175	NM_014484	MOCS3	molybdenum cofactor synthesis 3
chr19_-_4723755	0.175		DPP9	dipeptidyl-peptidase 9
chr12_+_94071150	0.173	NM_003805	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain
chr19_-_59070324	0.172	NM_003969	UBE2M	ubiquitin-conjugating enzyme E2M
chr5_-_147763345	0.172
chr4_+_48343502	0.172	NM_020846	SLAIN2	SLAIN motif family, member 2
chr7_+_44240555	0.172		YKT6	YKT6 v-SNARE homolog (S. cerevisiae)
chr20_-_34542205	0.171		SCAND1	SCAN domain containing 1
chr12_+_112856756	0.170		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chr2_+_234160374	0.170		ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr7_+_44084286	0.169		DBNL	drebrin-like
chr1_-_161102457	0.169	NM_001039711 NM_032998	DEDD	death effector domain containing
chr12_+_7080081	0.169		EMG1	EMG1 nucleolar protein homolog (S. cerevisiae)
chr21_-_33984865	0.169	NM_021254	C21orf59	chromosome 21 open reading frame 59
chrX_+_150565674	0.168		VMA21	VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr2_-_242556883	0.168	NM_001164356	THAP4	THAP domain containing 4
chr6_-_169653922	0.168		THBS2	thrombospondin 2
chr19_+_14551080	0.168	NM_213560	PKN1	protein kinase N1
chr1_-_31230594	0.167		LAPTM5	lysosomal protein transmembrane 5
chr11_+_65383631	0.166	NM_032223	PCNXL3	pecanex-like 3 (Drosophila)
chr10_+_93558281	0.166		TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr19_+_41771013	0.165		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr7_-_45151272	0.165		TBRG4	transforming growth factor beta regulator 4
chr19_+_41770976	0.165		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr10_-_51371150	0.164	NM_003631	AGAP8 LOC728407 PARG	ArfGAP with GTPase domain, ankyrin repeat and PH domain 8 poly (ADP-ribose) glycohydrolase pseudogene poly (ADP-ribose) glycohydrolase
chr1_+_169764174	0.164		C1orf112	chromosome 1 open reading frame 112
chrX_-_15872921	0.163		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr3_-_120068077	0.162	NM_001099678	LRRC58	leucine rich repeat containing 58
chr19_+_14551052	0.161		PKN1	protein kinase N1
chr1_-_1310522	0.161		AURKAIP1	aurora kinase A interacting protein 1
chr17_-_4843204	0.161	NM_001165417 NM_001165418 NM_003562	SLC25A11	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr10_-_43892675	0.161		HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr11_+_128563973	0.160		FLI1	Friend leukemia virus integration 1
chr22_+_35462125	0.160	NM_001008494	ISX	intestine-specific homeobox
chr3_+_184032849	0.159	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr5_-_32313069	0.159	NM_001040446	MTMR12	myotubularin related protein 12
chr14_+_105957569	0.158	NM_001134875 NM_001134876	C14orf80	chromosome 14 open reading frame 80
chr11_-_67169309	0.158		PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme
chr14_+_55034633	0.157		SAMD4A	sterile alpha motif domain containing 4A
chr7_+_44240606	0.156		YKT6	YKT6 v-SNARE homolog (S. cerevisiae)
chr19_+_14551087	0.156		PKN1	protein kinase N1
chr5_+_137801166	0.155		EGR1	early growth response 1
chr9_+_140172273	0.155	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr20_-_2641476	0.154		IDH3B	isocitrate dehydrogenase 3 (NAD+) beta
chr1_+_179712297	0.154	NM_173509	FAM163A	family with sequence similarity 163, member A
chr5_+_173315313	0.152	NM_030627	CPEB4	cytoplasmic polyadenylation element binding protein 4
chr11_-_116658738	0.152	NM_003904	ZNF259	zinc finger protein 259
chr9_-_125675571	0.151	NM_006626	ZBTB6	zinc finger and BTB domain containing 6
chr15_+_91260575	0.151	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr12_+_7080077	0.151		EMG1	EMG1 nucleolar protein homolog (S. cerevisiae)
chr6_+_41889191	0.151		BYSL	bystin-like
chr9_+_131218279	0.150	NM_001242352 NM_001242353 NM_001242354 NM_002540 NM_153432 NM_153435 NM_153439	ODF2	outer dense fiber of sperm tails 2
chr5_+_176853673	0.150	NM_001004105 NM_001004106 NM_002082	GRK6	G protein-coupled receptor kinase 6
chr2_+_234160216	0.150	NM_001190266 NM_001190267 NM_017974 NM_030803 NM_198890	ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr5_+_148520985	0.150	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chr9_-_37785013	0.150		EXOSC3	exosome component 3
chr22_+_39077979	0.150		TOMM22	translocase of outer mitochondrial membrane 22 homolog (yeast)
chr19_-_4723791	0.149		DPP9	dipeptidyl-peptidase 9
chr10_+_101491988	0.148		CUTC	cutC copper transporter homolog (E. coli)
chr5_+_176730779	0.147		PRELID1	PRELI domain containing 1
chr20_+_60877939	0.147		ADRM1	adhesion regulating molecule 1
chr6_-_30710219	0.147	NM_005803	FLOT1	flotillin 1
chrX_-_64754594	0.147		LAS1L	LAS1-like (S. cerevisiae)
chr7_+_44240638	0.147		YKT6	YKT6 v-SNARE homolog (S. cerevisiae)
chr3_+_52321853	0.146		GLYCTK	glycerate kinase
chr19_+_17420352	0.146		DDA1	DET1 and DDB1 associated 1
chr5_-_32312943	0.146		MTMR12	myotubularin related protein 12
chr6_-_153304590	0.145	NM_001142522	FBXO5	F-box protein 5
chr5_+_93954352	0.145	NM_032290	ANKRD32	ankyrin repeat domain 32
chr12_+_6602521	0.145		NCAPD2	non-SMC condensin I complex, subunit D2
chr9_+_131218678	0.145	NM_153433 NM_153440	ODF2	outer dense fiber of sperm tails 2
chr12_-_54653369	0.145	NM_001127321	CBX5	chromobox homolog 5
chr11_-_102714240	0.145	NM_002422	MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr5_+_179125362	0.145		CANX	calnexin
chr15_-_75135479	0.145		ULK3	unc-51-like kinase 3 (C. elegans)
chr8_-_95449131	0.144	NM_001205263	RAD54B	RAD54 homolog B (S. cerevisiae)
chr9_+_100396079	0.144		NCBP1	nuclear cap binding protein subunit 1, 80kDa
chr17_+_48450579	0.144	NM_001166131 NM_152463	EME1	essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr6_+_41888993	0.144		BYSL	bystin-like
chr7_+_766656	0.143		HEATR2	HEAT repeat containing 2
chr2_+_198381021	0.143	NM_001204094	MOB4	MOB family member 4, phocein
chr11_-_67169340	0.143	NM_001008709 NM_002708 NM_206873	PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme
chr15_+_24920540	0.143	NM_018958	C15orf2	chromosome 15 open reading frame 2
chr7_+_44240569	0.143	NM_006555	YKT6	YKT6 v-SNARE homolog (S. cerevisiae)
chr17_-_56595192	0.143	NM_004687	MTMR4	myotubularin related protein 4
chr12_+_12509947	0.142	NM_058169	LOH12CR1	loss of heterozygosity, 12, chromosomal region 1
chr3_-_119396220	0.142	NM_005694	COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr11_-_67169252	0.141		PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme
chr10_-_43892160	0.141	NM_001098208	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr3_+_52321835	0.140	NM_001144951 NM_145262	GLYCTK	glycerate kinase
chr19_-_47217576	0.140	NM_001079882	PRKD2	protein kinase D2
chr2_-_45838383	0.140	NM_018079	SRBD1	S1 RNA binding domain 1
chr6_+_41888964	0.139	NM_004053	BYSL	bystin-like
chr19_-_49567123	0.138	NM_006179	NTF4	neurotrophin 4
chr5_+_176730812	0.138	NM_013237	PRELID1	PRELI domain containing 1
chr10_-_43904598	0.138	NM_004966 NM_001098204	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr3_-_108308460	0.137	NM_020890	KIAA1524	KIAA1524
chr12_-_77459198	0.137	NM_203394	E2F7	E2F transcription factor 7
chr10_-_43904306	0.136	NM_001098205	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr13_-_60738078	0.136	NM_001042517	DIAPH3	diaphanous homolog 3 (Drosophila)
chr16_+_69373677	0.136		NIP7	nuclear import 7 homolog (S. cerevisiae)
chr15_-_75135480	0.136		ULK3	unc-51-like kinase 3 (C. elegans)
chr1_+_145438437	0.135	NM_006472	TXNIP	thioredoxin interacting protein
chr21_+_27107671	0.135		GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr11_+_128563993	0.135		FLI1	Friend leukemia virus integration 1
chr16_+_69373414	0.135	NM_001199434 NM_016101	NIP7	nuclear import 7 homolog (S. cerevisiae)
chr22_+_31478845	0.134	NM_001207017	SMTN	smoothelin
chr11_-_111944757	0.134	NM_001082619 NM_138789	PIH1D2	PIH1 domain containing 2
chr1_+_26485510	0.134	NM_024869	FAM110D	family with sequence similarity 110, member D
chr14_+_78174438	0.134		SLIRP	SRA stem-loop interacting RNA binding protein
chr6_-_153304093	0.134	NM_012177	FBXO5	F-box protein 5
chr16_+_67193828	0.134	NM_018378	FBXL8	F-box and leucine-rich repeat protein 8
chr19_-_14247267	0.133		ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr4_-_70626429	0.133	NM_014465	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr1_+_228353814	0.133		IBA57	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr2_+_96932024	0.132		CIAO1	cytosolic iron-sulfur protein assembly 1
chr2_-_153032141	0.132	NM_005843	STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr20_-_62178815	0.132	NM_080823	SRMS	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
chr5_-_6633149	0.131		NSUN2	NOP2/Sun domain family, member 2
chr4_+_1723233	0.131		TACC3	transforming, acidic coiled-coil containing protein 3
chr1_-_43637969	0.130	NM_006824 NM_001159936	EBNA1BP2	EBNA1 binding protein 2
chr11_+_128563772	0.130	NM_001167681 NM_002017	FLI1	Friend leukemia virus integration 1
chr5_+_87564729	0.129		LOC100505894	uncharacterized LOC100505894
chr4_-_99064300	0.129	NM_174952	C4orf37	chromosome 4 open reading frame 37
chr6_-_34216824	0.129	NM_001008703 NM_001008704 NM_178508	C6orf1	chromosome 6 open reading frame 1
chr15_-_75135524	0.129	NM_001099436	ULK3	unc-51-like kinase 3 (C. elegans)
chr22_+_39077975	0.129		TOMM22	translocase of outer mitochondrial membrane 22 homolog (yeast)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.35	3.28e-46	GO:0044260	cellular macromolecule metabolic process
1.49	7.81e-38	GO:0090304	nucleic acid metabolic process
1.29	7.93e-38	GO:0043170	macromolecule metabolic process
1.43	2.01e-37	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23	1.23e-32	GO:0044237	cellular metabolic process
1.35	2.19e-29	GO:0034641	cellular nitrogen compound metabolic process
1.48	1.56e-28	GO:0010467	gene expression
1.49	6.95e-28	GO:0016070	RNA metabolic process
1.33	1.54e-27	GO:0006807	nitrogen compound metabolic process
1.21	3.79e-27	GO:0044238	primary metabolic process
1.11	4.33e-26	GO:0009987	cellular process
1.18	6.59e-25	GO:0008152	metabolic process
1.86	2.43e-24	GO:0016071	mRNA metabolic process
1.82	6.99e-24	GO:0000278	mitotic cell cycle
1.60	1.09e-23	GO:0007049	cell cycle
1.47	2.46e-23	GO:0006996	organelle organization
1.74	2.52e-23	GO:0022403	cell cycle phase
1.67	2.56e-22	GO:0022402	cell cycle process
1.74	2.56e-21	GO:0006396	RNA processing
1.33	9.18e-21	GO:0071841	cellular component organization or biogenesis at cellular level
1.27	2.84e-19	GO:0071840	cellular component organization or biogenesis
1.90	9.58e-19	GO:0006397	mRNA processing
1.95	5.47e-16	GO:0008380	RNA splicing
1.30	6.73e-16	GO:0071842	cellular component organization at cellular level
1.25	1.13e-15	GO:0016043	cellular component organization
1.70	5.87e-15	GO:0006974	response to DNA damage stimulus
1.37	1.36e-14	GO:0009059	macromolecule biosynthetic process
1.29	1.43e-14	GO:0044267	cellular protein metabolic process
1.37	2.82e-14	GO:0034645	cellular macromolecule biosynthetic process
1.89	5.39e-14	GO:0048285	organelle fission
2.10	8.74e-14	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.10	8.74e-14	GO:0000398	nuclear mRNA splicing, via spliceosome
1.53	2.68e-13	GO:0046907	intracellular transport
1.89	2.92e-13	GO:0000280	nuclear division
1.89	2.92e-13	GO:0007067	mitosis
1.87	2.94e-13	GO:0000087	M phase of mitotic cell cycle
2.07	3.09e-13	GO:0000375	RNA splicing, via transesterification reactions
2.07	6.50e-13	GO:0022613	ribonucleoprotein complex biogenesis
2.02	2.11e-12	GO:0071843	cellular component biogenesis at cellular level
1.79	6.14e-12	GO:0070647	protein modification by small protein conjugation or removal
1.69	9.01e-12	GO:0000279	M phase
1.59	1.01e-11	GO:0006259	DNA metabolic process
1.95	1.75e-11	GO:0071156	regulation of cell cycle arrest
1.76	2.14e-11	GO:0010564	regulation of cell cycle process
1.48	2.64e-11	GO:0033554	cellular response to stress
1.80	3.65e-11	GO:0051325	interphase
1.83	8.03e-11	GO:0032446	protein modification by small protein conjugation
1.60	9.42e-11	GO:0044265	cellular macromolecule catabolic process
1.86	1.11e-10	GO:0016567	protein ubiquitination
1.79	1.11e-10	GO:0051329	interphase of mitotic cell cycle
1.55	1.12e-10	GO:0051726	regulation of cell cycle
1.94	1.47e-10	GO:0000075	cell cycle checkpoint
1.37	1.53e-10	GO:0051641	cellular localization
1.12	3.06e-10	GO:0050789	regulation of biological process
1.38	4.33e-10	GO:0044085	cellular component biogenesis
1.39	5.15e-10	GO:0051649	establishment of localization in cell
1.52	1.33e-09	GO:0009057	macromolecule catabolic process
1.24	2.26e-09	GO:0048522	positive regulation of cellular process
1.22	2.68e-09	GO:0019538	protein metabolic process
1.37	4.19e-09	GO:0010604	positive regulation of macromolecule metabolic process
1.68	5.63e-09	GO:0051301	cell division
1.20	6.41e-09	GO:0060255	regulation of macromolecule metabolic process
1.12	1.48e-08	GO:0050794	regulation of cellular process
1.65	1.88e-08	GO:0030163	protein catabolic process
1.69	2.08e-08	GO:0043632	modification-dependent macromolecule catabolic process
1.70	2.43e-08	GO:0006511	ubiquitin-dependent protein catabolic process
1.22	3.15e-08	GO:0048518	positive regulation of biological process
1.35	3.24e-08	GO:0031325	positive regulation of cellular metabolic process
1.33	3.76e-08	GO:0009893	positive regulation of metabolic process
1.67	6.09e-08	GO:0019941	modification-dependent protein catabolic process
1.48	7.66e-08	GO:0051276	chromosome organization
1.10	7.81e-08	GO:0065007	biological regulation
1.17	1.14e-07	GO:0019222	regulation of metabolic process
1.66	1.15e-07	GO:0051603	proteolysis involved in cellular protein catabolic process
1.23	1.16e-07	GO:0044249	cellular biosynthetic process
1.65	1.23e-07	GO:0044257	cellular protein catabolic process
1.18	1.61e-07	GO:0031323	regulation of cellular metabolic process
2.12	1.89e-07	GO:0051320	S phase
1.22	2.19e-07	GO:0009058	biosynthetic process
1.31	2.78e-07	GO:0033036	macromolecule localization
2.05	3.19e-07	GO:0042254	ribosome biogenesis
2.21	5.21e-07	GO:0006352	transcription initiation, DNA-dependent
1.25	6.09e-07	GO:0043412	macromolecule modification
1.85	6.96e-07	GO:0006260	DNA replication
2.09	8.60e-07	GO:0000084	S phase of mitotic cell cycle
1.95	1.06e-06	GO:0000082	G1/S transition of mitotic cell cycle
1.17	1.78e-06	GO:0080090	regulation of primary metabolic process
1.68	1.90e-06	GO:0007346	regulation of mitotic cell cycle
1.54	2.46e-06	GO:0016032	viral reproduction
1.33	2.81e-06	GO:0008104	protein localization
1.41	3.01e-06	GO:0065003	macromolecular complex assembly
1.64	3.23e-06	GO:0006366	transcription from RNA polymerase II promoter
1.81	4.49e-06	GO:0051169	nuclear transport
1.97	5.31e-06	GO:0006403	RNA localization
1.47	5.54e-06	GO:0070727	cellular macromolecule localization
1.81	5.79e-06	GO:0006913	nucleocytoplasmic transport
1.36	6.74e-06	GO:0045184	establishment of protein localization
2.22	8.17e-06	GO:0000216	M/G1 transition of mitotic cell cycle
1.98	8.85e-06	GO:0050657	nucleic acid transport
1.98	8.85e-06	GO:0050658	RNA transport
1.98	8.85e-06	GO:0051236	establishment of RNA localization
1.48	9.39e-06	GO:0007010	cytoskeleton organization
2.00	9.42e-06	GO:0031570	DNA integrity checkpoint
1.47	1.03e-05	GO:0034613	cellular protein localization
2.02	1.27e-05	GO:0000077	DNA damage checkpoint
1.23	1.32e-05	GO:0006464	protein modification process
1.35	1.48e-05	GO:0015031	protein transport
1.34	1.57e-05	GO:0010605	negative regulation of macromolecule metabolic process
2.08	1.69e-05	GO:0051340	regulation of ligase activity
1.83	1.70e-05	GO:0010498	proteasomal protein catabolic process
1.83	1.70e-05	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.16	2.00e-05	GO:0051168	nuclear export
2.16	2.00e-05	GO:0051351	positive regulation of ligase activity
1.56	2.30e-05	GO:0006281	DNA repair
2.16	2.54e-05	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.59	3.36e-05	GO:0006412	translation
1.62	3.56e-05	GO:0034660	ncRNA metabolic process
1.52	3.57e-05	GO:0006886	intracellular protein transport
2.14	4.36e-05	GO:0022618	ribonucleoprotein complex assembly
2.10	4.52e-05	GO:0071826	ribonucleoprotein complex subunit organization
1.30	6.76e-05	GO:0022607	cellular component assembly
2.15	7.04e-05	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.84	9.18e-05	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
2.05	9.50e-05	GO:0051438	regulation of ubiquitin-protein ligase activity
1.95	9.79e-05	GO:0051028	mRNA transport
1.88	1.07e-04	GO:0007093	mitotic cell cycle checkpoint
1.34	1.11e-04	GO:0043933	macromolecular complex subunit organization
2.12	1.20e-04	GO:0051443	positive regulation of ubiquitin-protein ligase activity
2.08	1.23e-04	GO:0000236	mitotic prometaphase
2.22	1.29e-04	GO:0006405	RNA export from nucleus
1.81	1.46e-04	GO:0031396	regulation of protein ubiquitination
1.28	1.51e-04	GO:0044248	cellular catabolic process
1.29	1.61e-04	GO:0051246	regulation of protein metabolic process
1.32	1.81e-04	GO:0006351	transcription, DNA-dependent
2.13	1.95e-04	GO:0006353	transcription termination, DNA-dependent
1.30	1.97e-04	GO:0032268	regulation of cellular protein metabolic process
1.30	2.24e-04	GO:0009892	negative regulation of metabolic process
2.19	2.29e-04	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.03	2.53e-04	GO:0031397	negative regulation of protein ubiquitination
1.92	2.92e-04	GO:0031398	positive regulation of protein ubiquitination
2.15	3.15e-04	GO:0051352	negative regulation of ligase activity
2.15	3.15e-04	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.35	3.30e-04	GO:0006915	apoptosis
2.01	4.04e-04	GO:0006364	rRNA processing
1.17	4.29e-04	GO:0010468	regulation of gene expression
2.01	5.20e-04	GO:0030330	DNA damage response, signal transduction by p53 class mediator
2.12	5.36e-04	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.34	5.45e-04	GO:0012501	programmed cell death
1.49	6.00e-04	GO:0016568	chromatin modification
1.18	6.11e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.17	6.43e-04	GO:0006367	transcription initiation from RNA polymerase II promoter
1.48	7.34e-04	GO:0034622	cellular macromolecular complex assembly
1.16	8.82e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.48	9.07e-04	GO:0044419	interspecies interaction between organisms
1.90	9.49e-04	GO:0007059	chromosome segregation
1.30	1.06e-03	GO:0008219	cell death
1.30	1.15e-03	GO:0016265	death
1.94	1.17e-03	GO:0016072	rRNA metabolic process
1.46	1.22e-03	GO:0032270	positive regulation of cellular protein metabolic process
1.17	1.56e-03	GO:0010556	regulation of macromolecule biosynthetic process
2.42	1.61e-03	GO:0006369	termination of RNA polymerase II transcription
1.45	1.62e-03	GO:0051247	positive regulation of protein metabolic process
1.41	1.82e-03	GO:0006325	chromatin organization
2.03	1.85e-03	GO:0006354	transcription elongation, DNA-dependent
1.28	2.13e-03	GO:0032774	RNA biosynthetic process
1.74	2.20e-03	GO:0051052	regulation of DNA metabolic process
1.39	2.27e-03	GO:0043065	positive regulation of apoptosis
2.17	2.28e-03	GO:0006406	mRNA export from nucleus
1.23	2.31e-03	GO:0009056	catabolic process
2.03	2.39e-03	GO:0000209	protein polyubiquitination
1.17	2.87e-03	GO:0048519	negative regulation of biological process
1.59	3.05e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.55	3.26e-03	GO:0051248	negative regulation of protein metabolic process
1.38	3.66e-03	GO:0043068	positive regulation of programmed cell death
2.13	3.92e-03	GO:0006368	transcription elongation from RNA polymerase II promoter
1.28	4.20e-03	GO:0031324	negative regulation of cellular metabolic process
1.38	4.70e-03	GO:0010942	positive regulation of cell death
1.38	5.97e-03	GO:0034621	cellular macromolecular complex subunit organization
1.31	5.97e-03	GO:0071844	cellular component assembly at cellular level
1.17	6.12e-03	GO:0048523	negative regulation of cellular process
1.51	6.23e-03	GO:0010608	posttranscriptional regulation of gene expression
1.29	6.52e-03	GO:0031328	positive regulation of cellular biosynthetic process
2.10	6.59e-03	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.10	6.59e-03	GO:0072395	signal transduction involved in cell cycle checkpoint
2.10	6.59e-03	GO:0072401	signal transduction involved in DNA integrity checkpoint
2.10	6.59e-03	GO:0072404	signal transduction involved in G1/S transition checkpoint
2.10	6.59e-03	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
2.10	6.59e-03	GO:0072422	signal transduction involved in DNA damage checkpoint
2.10	6.59e-03	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.10	6.59e-03	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
2.23	7.38e-03	GO:0050434	positive regulation of viral transcription
1.93	8.39e-03	GO:2000045	regulation of G1/S transition of mitotic cell cycle
2.06	8.45e-03	GO:0071158	positive regulation of cell cycle arrest
1.15	8.61e-03	GO:0031326	regulation of cellular biosynthetic process
1.28	9.30e-03	GO:0009891	positive regulation of biosynthetic process
1.15	9.96e-03	GO:0009889	regulation of biosynthetic process
1.53	1.00e-02	GO:0032269	negative regulation of cellular protein metabolic process
1.79	1.15e-02	GO:0042770	signal transduction in response to DNA damage
1.93	1.41e-02	GO:0031575	mitotic cell cycle G1/S transition checkpoint
1.93	1.41e-02	GO:0071779	G1/S transition checkpoint
1.66	1.42e-02	GO:0000226	microtubule cytoskeleton organization
1.15	1.65e-02	GO:0006950	response to stress
1.99	1.67e-02	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
2.43	1.69e-02	GO:0000080	G1 phase of mitotic cell cycle
1.55	1.96e-02	GO:0033365	protein localization to organelle
1.36	2.20e-02	GO:0070271	protein complex biogenesis
1.42	2.56e-02	GO:0006917	induction of apoptosis
1.63	2.60e-02	GO:0031400	negative regulation of protein modification process
1.28	2.67e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.14	2.71e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.34	2.78e-02	GO:0051318	G1 phase
1.30	2.87e-02	GO:0051254	positive regulation of RNA metabolic process
1.42	3.05e-02	GO:0012502	induction of programmed cell death
1.73	3.33e-02	GO:0051640	organelle localization
1.45	3.39e-02	GO:0031401	positive regulation of protein modification process
1.28	3.47e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.00	3.62e-02	GO:0048524	positive regulation of viral reproduction
1.35	3.64e-02	GO:0006461	protein complex assembly
1.54	3.87e-02	GO:0006605	protein targeting
1.93	3.99e-02	GO:0006302	double-strand break repair
2.05	4.88e-02	GO:0046782	regulation of viral transcription

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	3.16e-72	GO:0044424	intracellular part
1.16	2.64e-70	GO:0005622	intracellular
1.33	1.12e-60	GO:0005634	nucleus
1.60	2.93e-57	GO:0044428	nuclear part
1.19	8.91e-57	GO:0043229	intracellular organelle
1.19	3.09e-56	GO:0043226	organelle
1.63	2.55e-52	GO:0031981	nuclear lumen
1.20	4.08e-52	GO:0043231	intracellular membrane-bounded organelle
1.20	5.04e-52	GO:0043227	membrane-bounded organelle
1.53	1.87e-49	GO:0031974	membrane-enclosed lumen
1.53	6.15e-48	GO:0043233	organelle lumen
1.53	3.73e-47	GO:0070013	intracellular organelle lumen
1.61	9.15e-35	GO:0005654	nucleoplasm
1.47	1.05e-34	GO:0005829	cytosol
1.25	6.58e-34	GO:0044446	intracellular organelle part
1.25	7.32e-34	GO:0044422	organelle part
1.39	5.44e-32	GO:0043228	non-membrane-bounded organelle
1.39	5.44e-32	GO:0043232	intracellular non-membrane-bounded organelle
1.17	1.38e-31	GO:0005737	cytoplasm
1.32	2.17e-30	GO:0032991	macromolecular complex
1.19	9.86e-21	GO:0044444	cytoplasmic part
1.78	7.63e-20	GO:0005730	nucleolus
1.29	2.41e-19	GO:0043234	protein complex
1.72	1.70e-17	GO:0030529	ribonucleoprotein complex
1.65	3.27e-15	GO:0005694	chromosome
2.30	2.95e-14	GO:0005681	spliceosomal complex
1.65	1.40e-12	GO:0044427	chromosomal part
1.48	9.13e-11	GO:0044451	nucleoplasm part
1.64	2.17e-08	GO:0005815	microtubule organizing center
1.43	7.71e-08	GO:0015630	microtubule cytoskeleton
2.28	1.38e-07	GO:0071013	catalytic step 2 spliceosome
1.95	1.71e-07	GO:0000793	condensed chromosome
1.81	4.77e-07	GO:0031252	cell leading edge
1.74	5.88e-07	GO:0000228	nuclear chromosome
1.91	5.92e-07	GO:0000775	chromosome, centromeric region
1.76	3.11e-06	GO:0005819	spindle
1.65	7.61e-06	GO:0000785	chromatin
1.67	8.72e-06	GO:0005813	centrosome
1.84	1.14e-05	GO:0000151	ubiquitin ligase complex
1.75	1.53e-05	GO:0044454	nuclear chromosome part
2.06	3.24e-05	GO:0030027	lamellipodium
2.79	3.32e-05	GO:0030532	small nuclear ribonucleoprotein complex
1.03	6.07e-05	GO:0044464	cell part
2.01	6.49e-05	GO:0000776	kinetochore
1.03	6.52e-05	GO:0005623	cell
2.05	1.44e-04	GO:0000779	condensed chromosome, centromeric region
2.09	1.44e-04	GO:0000777	condensed chromosome kinetochore
2.94	2.62e-04	GO:0005689	U12-type spliceosomal complex
1.94	3.16e-04	GO:0001726	ruffle
1.58	3.98e-04	GO:0016604	nuclear body
1.21	4.51e-04	GO:0005856	cytoskeleton
2.09	8.28e-04	GO:0000502	proteasome complex
1.21	2.00e-03	GO:0005739	mitochondrion
1.90	2.03e-03	GO:0046930	pore complex
2.03	2.83e-03	GO:0044450	microtubule organizing center part
1.50	3.82e-03	GO:0005635	nuclear envelope
1.96	4.18e-03	GO:0005643	nuclear pore
1.86	9.70e-03	GO:0031461	cullin-RING ubiquitin ligase complex
1.94	1.08e-02	GO:0000922	spindle pole
1.83	1.09e-02	GO:0000790	nuclear chromatin
1.22	1.15e-02	GO:0044430	cytoskeletal part
1.27	1.85e-02	GO:0031967	organelle envelope
1.66	1.86e-02	GO:0016607	nuclear speck
1.26	3.25e-02	GO:0031975	envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.24	3.64e-48	GO:0005515	protein binding
1.11	5.45e-33	GO:0005488	binding
1.61	2.63e-20	GO:0003723	RNA binding
1.28	3.00e-20	GO:0003676	nucleic acid binding
1.27	5.84e-12	GO:0000166	nucleotide binding
1.23	1.41e-06	GO:0017076	purine nucleotide binding
1.23	1.73e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.23	2.03e-06	GO:0032553	ribonucleotide binding
1.23	2.03e-06	GO:0032555	purine ribonucleotide binding
1.24	1.04e-05	GO:0030554	adenyl nucleotide binding
1.24	1.30e-05	GO:0032559	adenyl ribonucleotide binding
1.24	1.56e-05	GO:0005524	ATP binding
1.11	1.94e-05	GO:0003824	catalytic activity
1.81	6.54e-05	GO:0004386	helicase activity
1.33	1.10e-04	GO:0019899	enzyme binding
1.84	1.04e-03	GO:0008026	ATP-dependent helicase activity
1.84	1.04e-03	GO:0070035	purine NTP-dependent helicase activity
1.39	1.05e-03	GO:0016874	ligase activity
1.56	1.69e-03	GO:0004842	ubiquitin-protein ligase activity
1.16	1.92e-03	GO:0003677	DNA binding
1.52	4.17e-03	GO:0019787	small conjugating protein ligase activity
1.90	4.38e-03	GO:0008135	translation factor activity, nucleic acid binding
1.40	5.84e-03	GO:0000988	protein binding transcription factor activity
1.40	5.84e-03	GO:0000989	transcription factor binding transcription factor activity
1.53	6.56e-03	GO:0003713	transcription coactivator activity
1.39	8.32e-03	GO:0003712	transcription cofactor activity
1.23	1.18e-02	GO:0030528	transcription regulator activity
1.36	1.50e-02	GO:0004674	protein serine/threonine kinase activity
1.26	2.36e-02	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.26	2.41e-02	GO:0017111	nucleoside-triphosphatase activity
1.40	2.75e-02	GO:0016563	transcription activator activity
2.14	2.76e-02	GO:0004812	aminoacyl-tRNA ligase activity
2.14	2.76e-02	GO:0016875	ligase activity, forming carbon-oxygen bonds
2.14	2.76e-02	GO:0016876	ligase activity, forming aminoacyl-tRNA and related compounds
1.23	2.76e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.41	3.21e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.25	3.22e-02	GO:0016817	hydrolase activity, acting on acid anhydrides
1.25	3.47e-02	GO:0016462	pyrophosphatase activity
1.43	4.85e-02	GO:0016881	acid-amino acid ligase activity