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Motif ID: ESR1.p2

Z-value: 0.604

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_33010174	0.669	NM_001191322 NM_001191323 NM_013372	GREM1	gremlin 1
chr17_-_43045612	0.594	NM_006688	C1QL1	complement component 1, q subcomponent-like 1
chr11_-_63381840	0.473		PLA2G16	phospholipase A2, group XVI
chr11_-_63381485	0.471		PLA2G16	phospholipase A2, group XVI
chr11_-_63381940	0.463	NM_001128203	PLA2G16	phospholipase A2, group XVI
chr11_-_63381907	0.462	NM_007069	PLA2G16	phospholipase A2, group XVI
chr17_-_48264039	0.445		COL1A1	collagen, type I, alpha 1
chr13_+_76210449	0.438		LMO7	LIM domain 7
chr1_+_215256559	0.414	NM_001017425 NM_014217	KCNK2	potassium channel, subfamily K, member 2
chr9_+_90112419	0.406		DAPK1	death-associated protein kinase 1
chr9_+_90112754	0.406	NM_004938	DAPK1	death-associated protein kinase 1
chr17_-_19290471	0.396	NM_001198695 NM_002404	MFAP4	microfibrillar-associated protein 4
chr16_+_55515468	0.394	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr12_-_124457099	0.373	NM_025140	CCDC92	coiled-coil domain containing 92
chr3_+_154797435	0.370	NM_000902	MME	membrane metallo-endopeptidase
chr2_-_175869910	0.364	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr1_+_77748286	0.315	NM_012093	AK5	adenylate kinase 5
chr9_-_89562103	0.309	NM_002048	GAS1	growth arrest-specific 1
chr8_+_16884745	0.305	NM_181723	EFHA2	EF-hand domain family, member A2
chr7_+_44143945	0.295	NM_001129	AEBP1	AE binding protein 1
chr1_+_77747727	0.269		AK5	adenylate kinase 5
chr10_+_115438934	0.263	NM_033340	CASP7	caspase 7, apoptosis-related cysteine peptidase
chr14_+_96505566	0.261	NM_001252507	C14orf132	chromosome 14 open reading frame 132
chr15_-_81616439	0.259	NM_181900	STARD5	StAR-related lipid transfer (START) domain containing 5
chr6_-_52441714	0.259		TRAM2	translocation associated membrane protein 2
chr5_-_150537306	0.259		ANXA6	annexin A6
chr2_-_127864505	0.258	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chrX_-_150067127	0.253	NM_001184808 NM_001242614 NM_031462 NM_134445 NM_134446	CD99L2	CD99 molecule-like 2
chr1_+_245133283	0.246		EFCAB2	EF-hand calcium binding domain 2
chr6_-_52441815	0.245	NM_012288	TRAM2	translocation associated membrane protein 2
chr6_+_52226866	0.243	NM_133367	PAQR8	progestin and adipoQ receptor family member VIII
chr1_+_245133628	0.235	NM_001143943	EFCAB2	EF-hand calcium binding domain 2
chrX_-_118827060	0.232		SEPT6	septin 6
chr1_-_92351476	0.230		TGFBR3	transforming growth factor, beta receptor III
chr6_-_154831788	0.230		CNKSR3	CNKSR family member 3
chr7_+_44144002	0.228		AEBP1	AE binding protein 1
chr6_-_154831652	0.227		CNKSR3	CNKSR family member 3
chr6_-_154831704	0.226	NM_173515	CNKSR3	CNKSR family member 3
chr11_-_74022609	0.223	NM_182904	P4HA3	prolyl 4-hydroxylase, alpha polypeptide III
chr16_-_3074225	0.217	NM_001002017 NM_001002018 NM_017885	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)
chr10_+_72972268	0.216	NM_001244889 NM_170744	UNC5B	unc-5 homolog B (C. elegans)
chr1_+_159750756	0.214	NM_017823	DUSP23	dual specificity phosphatase 23
chr6_+_72892371	0.214		RIMS1	regulating synaptic membrane exocytosis 1
chr1_+_145477018	0.214	NM_153713	LIX1L	Lix1 homolog (mouse)-like
chrX_-_150067062	0.210		CD99L2	CD99 molecule-like 2
chr22_+_38142255	0.208		TRIOBP	TRIO and F-actin binding protein
chr19_+_15218141	0.207	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr22_+_38142316	0.206		TRIOBP	TRIO and F-actin binding protein
chr2_-_85641153	0.199		CAPG	capping protein (actin filament), gelsolin-like
chr4_-_89618928	0.199	NM_153757	NAP1L5	nucleosome assembly protein 1-like 5
chr14_+_105941061	0.199	NM_001312	CRIP2	cysteine-rich protein 2
chr19_-_3047632	0.199	NM_001144761	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr1_-_92351613	0.195	NM_001195683 NM_003243	TGFBR3	transforming growth factor, beta receptor III
chr22_-_19929447	0.195		TXNRD2	thioredoxin reductase 2
chr5_+_176237435	0.190	NM_133369	UNC5A	unc-5 homolog A (C. elegans)
chr6_+_24495166	0.190	NM_001080 NM_170740	ALDH5A1	aldehyde dehydrogenase 5 family, member A1
chr2_-_85641128	0.185		CAPG	capping protein (actin filament), gelsolin-like
chr3_-_179169180	0.184		GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr8_+_27182995	0.183	NM_173176	PTK2B	PTK2B protein tyrosine kinase 2 beta
chr2_-_99552677	0.181	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr11_-_3186507	0.177		OSBPL5	oxysterol binding protein-like 5
chr13_-_44361032	0.176	NM_001242863 NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr3_+_154797644	0.175	NM_007287	MME	membrane metallo-endopeptidase
chr9_-_115774471	0.172	NM_001101338	ZNF883	zinc finger protein 883
chr10_+_81892497	0.170		PLAC9	placenta-specific 9
chr7_-_50861114	0.170	NM_001001555	GRB10	growth factor receptor-bound protein 10
chr7_-_47621635	0.169		TNS3	tensin 3
chr3_-_81810618	0.168		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr4_+_150999412	0.166	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr1_+_77747602	0.165	NM_174858	AK5	adenylate kinase 5
chr4_-_57976550	0.164	NM_001253835 NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr14_+_105953256	0.164	NM_001311	CRIP1	cysteine-rich protein 1 (intestinal)
chr3_+_69788562	0.164	NM_198159	MITF	microphthalmia-associated transcription factor
chr11_+_65190267	0.162		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr5_+_139028483	0.159		CXXC5	CXXC finger protein 5
chr16_+_30907927	0.155	NM_001142544 NM_001330	CTF1	cardiotrophin 1
chr3_-_8811044	0.154		OXTR	oxytocin receptor
chr20_+_62694456	0.154		TCEA2	transcription elongation factor A (SII), 2
chr7_-_47621741	0.153	NM_022748	TNS3	tensin 3
chr19_-_44124013	0.152	NM_182498	ZNF428	zinc finger protein 428
chr22_-_19929333	0.152	NM_006440	TXNRD2	thioredoxin reductase 2
chr5_-_81046858	0.152		SSBP2	single-stranded DNA binding protein 2
chr3_-_66551341	0.151		LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
chr22_+_38142230	0.149	NM_007032 NM_138632	TRIOBP	TRIO and F-actin binding protein
chr10_-_62703822	0.148	NM_001242359 NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr10_+_81892257	0.147	NM_001012973	PLAC9	placenta-specific 9
chr5_+_110559647	0.147	NM_001744	CAMK4	calcium/calmodulin-dependent protein kinase IV
chr9_-_22009270	0.146	NM_004936 NM_078487	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_+_110230417	0.145	NM_000561 NM_146421	GSTM1	glutathione S-transferase mu 1
chr11_-_3186522	0.145		OSBPL5	oxysterol binding protein-like 5
chr19_-_44123732	0.145		ZNF428	zinc finger protein 428
chr6_-_46459710	0.145	NM_001251973	RCAN2	regulator of calcineurin 2
chr3_-_171528227	0.141	NM_001130081 NM_002662	PLD1	phospholipase D1, phosphatidylcholine-specific
chr22_+_44319685	0.141		PNPLA3	patatin-like phospholipase domain containing 3
chrX_+_117861523	0.141	NM_001560	IL13RA1	interleukin 13 receptor, alpha 1
chr9_-_138987096	0.141	NM_144653	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing
chr10_+_12391471	0.140	NM_020397 NM_153498	CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr6_-_153452383	0.139	NM_012419	RGS17	regulator of G-protein signaling 17
chr6_-_46459010	0.137	NM_001251974	RCAN2	regulator of calcineurin 2
chr9_-_123342258	0.135	NM_001011649 NM_018249	CDK5RAP2	CDK5 regulatory subunit associated protein 2
chr22_+_44319674	0.135		PNPLA3	patatin-like phospholipase domain containing 3
chr22_-_19929250	0.135		TXNRD2	thioredoxin reductase 2
chr12_+_120105656	0.135	NM_006253	PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr5_-_10761341	0.135		DAP	death-associated protein
chr11_-_2162340	0.134	NM_001127598	IGF2	insulin-like growth factor 2 (somatomedin A)
chr3_+_126261178	0.133		CHST13	carbohydrate (chondroitin 4) sulfotransferase 13
chr11_+_47270433	0.132	NM_001130102	NR1H3	nuclear receptor subfamily 1, group H, member 3
chr15_-_49338496	0.131	NM_001193489 NM_014701	SECISBP2L	SECIS binding protein 2-like
chr19_+_49617631	0.130		LIN7B	lin-7 homolog B (C. elegans)
chr22_+_44319618	0.129	NM_025225	PNPLA3	patatin-like phospholipase domain containing 3
chr9_+_97488993	0.129		C9orf3	chromosome 9 open reading frame 3
chr17_-_27044728	0.128	NM_001144942 NM_031934	RAB34	RAB34, member RAS oncogene family
chr10_+_81892429	0.127		PLAC9	placenta-specific 9
chr9_+_123963728	0.127		GSN	gelsolin
chr5_+_179247911	0.127		SQSTM1	sequestosome 1
chr11_+_64001974	0.126	NM_001243733 NM_003377	VEGFB	vascular endothelial growth factor B
chr2_-_200335988	0.125	NM_015265	SATB2	SATB homeobox 2
chr13_+_51483813	0.124	NM_001142279 NM_024570	RNASEH2B	ribonuclease H2, subunit B
chr14_+_79745653	0.124	NM_001105250 NM_138970	NRXN3	neurexin 3
chr5_+_149569810	0.123		SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr14_+_100438095	0.123		EVL	Enah/Vasp-like
chr7_-_139477437	0.123	NM_001113239 NM_022740	HIPK2	homeodomain interacting protein kinase 2
chr5_-_10761179	0.123		DAP	death-associated protein
chr19_+_4304590	0.123	NM_024333	FSD1	fibronectin type III and SPRY domain containing 1
chr19_+_49617611	0.123	NM_022165	LIN7B	lin-7 homolog B (C. elegans)
chr7_-_74267824	0.122	NM_173537	GTF2IRD2B GTF2IRD2	GTF2I repeat domain containing 2B GTF2I repeat domain containing 2
chr1_-_145039631	0.122	NM_001198832	PDE4DIP	phosphodiesterase 4D interacting protein
chr16_-_30006911	0.122		HIRIP3	HIRA interacting protein 3
chr15_+_62682682	0.121		TLN2	talin 2
chr6_+_168841873	0.121		SMOC2	SPARC related modular calcium binding 2
chr5_-_10761344	0.120	NM_004394	DAP	death-associated protein
chr9_+_97488943	0.120	NM_001193331 NM_032823	C9orf3	chromosome 9 open reading frame 3
chr9_-_140083010	0.120		ANAPC2	anaphase promoting complex subunit 2
chr6_+_168841829	0.120	NM_001166412 NM_022138	SMOC2	SPARC related modular calcium binding 2
chr13_+_103451398	0.120	NM_001159596 NM_017693	BIVM	basic, immunoglobulin-like variable motif containing
chr5_+_179247903	0.120		SQSTM1	sequestosome 1
chr19_-_37958338	0.119	NM_152484	ZNF569	zinc finger protein 569
chr17_-_40540576	0.119		STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
chr17_-_78194085	0.119	NM_000199	SGSH	N-sulfoglucosamine sulfohydrolase
chr3_-_8811263	0.118	NM_000916	OXTR	oxytocin receptor
chr1_+_201476283	0.118
chr1_+_1072274	0.118		LOC254099	uncharacterized LOC254099
chr20_-_36889173	0.117	NM_001029864	KIAA1755	KIAA1755
chr3_-_66550844	0.117	NM_015541	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
chr5_-_178157597	0.114	NM_005649	ZNF354A	zinc finger protein 354A
chr4_-_8073711	0.114		ABLIM2	actin binding LIM protein family, member 2
chr3_-_81810816	0.113		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr12_+_56661026	0.112	NM_001099337	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr3_+_58318597	0.112	NM_017771	PXK	PX domain containing serine/threonine kinase
chr5_+_179248089	0.111		SQSTM1	sequestosome 1
chr17_+_1733263	0.111	NM_002945	RPA1	replication protein A1, 70kDa
chr6_+_148663953	0.109		SASH1	SAM and SH3 domain containing 1
chr7_+_143079354	0.109		ZYX	zyxin
chr11_-_73309090	0.108	NM_015159	FAM168A	family with sequence similarity 168, member A
chr19_+_10531128	0.107	NM_001111307	PDE4A	phosphodiesterase 4A, cAMP-specific
chr9_+_4985243	0.107	NM_004972	JAK2	Janus kinase 2
chr14_+_105953531	0.107		CRIP1	cysteine-rich protein 1 (intestinal)
chr15_-_93616358	0.107	NM_001166286	RGMA	RGM domain family, member A
chr22_+_50919970	0.106	NM_024866 NM_001253845	ADM2	adrenomedullin 2
chr19_-_44809126	0.106	NM_004234	ZNF235	zinc finger protein 235
chr1_-_15850718	0.106		CASP9	caspase 9, apoptosis-related cysteine peptidase
chr6_+_83903031	0.106	NM_033411	RWDD2A	RWD domain containing 2A
chr15_-_93616308	0.106		RGMA	RGM domain family, member A
chr9_+_101705710	0.105	NM_001855	COL15A1	collagen, type XV, alpha 1
chr17_-_33700619	0.104	NM_001104587 NM_001104588 NM_001104589 NM_001104590 NM_152270	SLFN11	schlafen family member 11
chr8_+_27183062	0.104	NM_173175	PTK2B	PTK2B protein tyrosine kinase 2 beta
chr1_-_201476218	0.104		CSRP1	cysteine and glycine-rich protein 1
chr2_-_180129245	0.104	NM_178123	SESTD1	SEC14 and spectrin domains 1
chr1_+_150122095	0.103	NM_016274	PLEKHO1	pleckstrin homology domain containing, family O member 1
chr7_+_2443205	0.103		CHST12	carbohydrate (chondroitin 4) sulfotransferase 12
chr22_+_42086546	0.103	NM_001142964	C22orf46	chromosome 22 open reading frame 46
chr12_-_133532847	0.103	NM_183238 NM_001164715	ZNF605	zinc finger protein 605
chr10_-_131909061	0.102		LOC387723	uncharacterized LOC387723
chr4_+_148402244	0.101		EDNRA	endothelin receptor type A
chr22_-_19435211	0.101		C22orf39 HIRA	chromosome 22 open reading frame 39 HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_-_15850692	0.101		CASP9	caspase 9, apoptosis-related cysteine peptidase
chr9_-_16870664	0.101		BNC2	basonuclin 2
chr16_+_8768403	0.100	NM_020686	ABAT	4-aminobutyrate aminotransferase
chr5_+_32710742	0.100	NM_001204376	NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr6_+_72596405	0.100		RIMS1	regulating synaptic membrane exocytosis 1
chr5_+_179247841	0.100	NM_003900	SQSTM1	sequestosome 1
chr1_-_201476241	0.100		CSRP1	cysteine and glycine-rich protein 1
chr19_+_54371150	0.099		MYADM	myeloid-associated differentiation marker
chr1_+_245133652	0.099		EFCAB2	EF-hand calcium binding domain 2
chrX_+_134166318	0.098	NM_001078171	FAM127A	family with sequence similarity 127, member A
chrX_-_153707595	0.098	NM_006014	LAGE3	L antigen family, member 3
chr19_-_49222956	0.098	NM_001130915	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator
chr2_+_202316391	0.098	NM_001206864 NM_018571	STRADB	STE20-related kinase adaptor beta
chr22_+_17640241	0.097		CECR5-AS1	CECR5 antisense RNA 1 (non-protein coding)
chr6_+_107811272	0.097	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr17_+_17206626	0.097	NM_020201	NT5M	5',3'-nucleotidase, mitochondrial
chrX_-_118827116	0.097		SEPT6	septin 6
chr7_+_100209724	0.096	NM_001040097	MOSPD3	motile sperm domain containing 3
chr9_+_79074067	0.096	NM_001097633 NM_001490	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2
chr14_+_74003817	0.096	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr1_+_22351984	0.095		LINC00339	long intergenic non-protein coding RNA 339
chr11_-_2019007	0.095		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr6_+_148663728	0.095	NM_015278	SASH1	SAM and SH3 domain containing 1
chr19_-_18717631	0.094	NM_004750	CRLF1	cytokine receptor-like factor 1
chr8_+_38854431	0.094	NM_003816	ADAM9	ADAM metallopeptidase domain 9

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.91	4.20e-03	GO:0071495	cellular response to endogenous stimulus
1.88	6.40e-03	GO:0043434	response to peptide hormone stimulus
1.90	1.03e-02	GO:0032870	cellular response to hormone stimulus
1.13	3.44e-02	GO:0050794	regulation of cellular process
1.95	3.78e-02	GO:0030036	actin cytoskeleton organization
1.87	3.87e-02	GO:0030029	actin filament-based process
1.99	4.08e-02	GO:0071375	cellular response to peptide hormone stimulus
1.45	4.08e-02	GO:0032879	regulation of localization
1.29	4.64e-02	GO:0048523	negative regulation of cellular process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	1.16e-10	GO:0005622	intracellular
1.12	1.79e-08	GO:0044424	intracellular part
1.17	4.22e-08	GO:0005737	cytoplasm
1.15	5.82e-03	GO:0044444	cytoplasmic part
1.84	6.57e-03	GO:0015629	actin cytoskeleton
1.09	1.25e-02	GO:0043229	intracellular organelle
1.09	1.41e-02	GO:0043226	organelle
1.27	1.65e-02	GO:0005829	cytosol
1.10	1.85e-02	GO:0043231	intracellular membrane-bounded organelle
1.10	2.24e-02	GO:0043227	membrane-bounded organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	1.91e-08	GO:0005488	binding
1.18	2.48e-07	GO:0005515	protein binding
3.03	4.90e-02	GO:0005097	Rab GTPase activator activity