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• Activity deltas table
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Motif ID: EWSR1-FLI1.p2

Z-value: 0.604

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_54423448	0.914	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr1_+_186798031	0.764	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr2_+_113816214	0.629	NM_173170	IL36RN	interleukin 36 receptor antagonist
chr7_+_16793320	0.620	NM_014399	TSPAN13	tetraspanin 13
chr19_+_48774653	0.549	NM_153608	ZNF114	zinc finger protein 114
chr11_-_118123001	0.508	NM_198275	MPZL3	myelin protein zero-like 3
chr17_-_34122547	0.489	NM_001032278 NM_024302	MMP28	matrix metallopeptidase 28
chr8_-_38008332	0.435	NM_000349	STAR	steroidogenic acute regulatory protein
chr20_+_6748744	0.419	NM_001200	BMP2	bone morphogenetic protein 2
chr10_-_103874661	0.365	NM_003893	LDB1	LIM domain binding 1
chrX_+_585078	0.358	NM_000451 NM_006883	SHOX	short stature homeobox
chrY_+_535078	0.353	NM_000451 NM_006883	SHOX	short stature homeobox
chr11_+_10476665	0.348	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr12_+_2904289	0.340		FKBP4	FK506 binding protein 4, 59kDa
chr5_-_148442606	0.339	NM_024577	SH3TC2	SH3 domain and tetratricopeptide repeats 2
chr13_-_76055872	0.325	NM_014832	TBC1D4	TBC1 domain family, member 4
chr12_+_2904101	0.324	NM_002014	FKBP4	FK506 binding protein 4, 59kDa
chr6_-_10412606	0.323	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_-_291168	0.323	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chrY_+_1351570	0.318	NM_001161530 NM_172247	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr1_+_167599329	0.317	NM_052862	RCSD1	RCSD domain containing 1
chr2_+_113816684	0.316	NM_012275	IL36RN	interleukin 36 receptor antagonist
chrX_+_1401570	0.315	NM_001161530 NM_172247	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr12_+_46123495	0.307	NM_152641	ARID2	AT rich interactive domain 2 (ARID, RFX-like)
chr9_-_124990706	0.302	NM_001242333	LHX6	LIM homeobox 6
chr8_-_145559831	0.299	NM_031309	SCRT1	scratch homolog 1, zinc finger protein (Drosophila)
chr19_-_51472816	0.296	NM_002774	KLK6	kallikrein-related peptidase 6
chr7_+_69064316	0.293		AUTS2	autism susceptibility candidate 2
chr1_+_202163117	0.269	NM_001017403	LGR6	leucine-rich repeat containing G protein-coupled receptor 6
chr6_-_143266283	0.267	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr10_-_103879933	0.246	NM_001113407	LDB1	LIM domain binding 1
chr2_+_106361404	0.238	NM_001004722 NM_003581	NCK2	NCK adaptor protein 2
chr1_-_6546013	0.234	NM_001042665	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_+_153330329	0.225	NM_002965	S100A9	S100 calcium binding protein A9
chr19_-_52900966	0.217		LOC284373	uncharacterized LOC284373
chr19_-_51487070	0.213	NM_139277 NM_001207053 NM_001243126 NM_005046	KLK7	kallikrein-related peptidase 7
chr1_-_153588789	0.198	NM_020672	S100A14	S100 calcium binding protein A14
chr19_-_291335	0.194	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr11_-_74442429	0.193		CHRDL2	chordin-like 2
chr6_+_26383323	0.189	NM_001197238 NM_001197239 NM_001197240 NM_006995 NM_181531 NM_001197237	BTN2A2	butyrophilin, subfamily 2, member A2
chrX_-_78623006	0.186	NM_001171581 NM_004867	ITM2A	integral membrane protein 2A
chr7_+_36429388	0.186	NM_018685	ANLN	anillin, actin binding protein
chr1_-_226926875	0.185	NM_002221	ITPKB	inositol-trisphosphate 3-kinase B
chr12_+_46123476	0.183		ARID2	AT rich interactive domain 2 (ARID, RFX-like)
chr11_+_10477480	0.183	NM_001025390	AMPD3	adenosine monophosphate deaminase 3
chr14_+_70346113	0.177	NM_001034852 NM_022137	SMOC1	SPARC related modular calcium binding 1
chr7_+_69063768	0.174	NM_001127231 NM_001127232 NM_015570	AUTS2	autism susceptibility candidate 2
chr9_-_124989755	0.172	NM_001242334	LHX6	LIM homeobox 6
chr1_+_93544786	0.170	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr4_+_84457256	0.168		AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr13_+_47127295	0.168	NM_001164211 NM_001164213 NM_015116	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1
chr15_-_59041933	0.168	NM_001110	ADAM10	ADAM metallopeptidase domain 10
chr13_+_47127312	0.165		LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1
chr18_+_43405544	0.165	NM_213602	SIGLEC15	sialic acid binding Ig-like lectin 15
chr16_+_69166522	0.164		CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)
chr5_+_35856990	0.163	NM_002185	IL7R	interleukin 7 receptor
chr19_-_42759279	0.161	NM_006494	ERF	Ets2 repressor factor
chr2_-_55496347	0.160	NM_002453	MTIF2	mitochondrial translational initiation factor 2
chr15_-_59041777	0.159		ADAM10	ADAM metallopeptidase domain 10
chr3_-_48471401	0.158	NM_001130082	PLXNB1	plexin B1
chr5_-_142000899	0.157	NM_001144892	FGF1	fibroblast growth factor 1 (acidic)
chr16_+_69166487	0.150	NM_032830	CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)
chr20_-_62284701	0.147	NM_015894	STMN3	stathmin-like 3
chrX_+_48644961	0.147	NM_002049	GATA1	GATA binding protein 1 (globin transcription factor 1)
chr5_+_156887026	0.146	NM_001099287 NM_001172292	NIPAL4	NIPA-like domain containing 4
chr1_-_156470565	0.146		MEF2D	myocyte enhancer factor 2D
chr2_-_113542970	0.143	NM_000575	IL1A	interleukin 1, alpha
chr1_-_169680677	0.143	NM_000655	SELL	selectin L
chr1_-_156470538	0.139		MEF2D	myocyte enhancer factor 2D
chr11_-_74442185	0.139	NM_015424	CHRDL2	chordin-like 2
chr8_-_95487284	0.136	NM_001205262 NM_012415	RAD54B	RAD54 homolog B (S. cerevisiae)
chr1_-_156470506	0.135	NM_005920	MEF2D	myocyte enhancer factor 2D
chr13_+_47127383	0.134		LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1
chr12_+_109273856	0.134	NM_001917	DAO	D-amino-acid oxidase
chr1_+_117452359	0.132	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr19_-_42759151	0.131		ERF	Ets2 repressor factor
chr5_+_86563594	0.128		RASA1	RAS p21 protein activator (GTPase activating protein) 1
chr9_+_135854097	0.126	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr1_-_11042093	0.126	NM_001170754	C1orf127	chromosome 1 open reading frame 127
chr17_+_38137088	0.125		PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr11_+_1074869	0.125	NM_002457	MUC2	mucin 2, oligomeric mucus/gel-forming
chrX_-_49965003	0.123	NM_139289	AKAP4	A kinase (PRKA) anchor protein 4
chr1_-_226497415	0.123		LIN9	lin-9 homolog (C. elegans)
chr1_-_48462561	0.120	NM_001194986	LOC388630	UPF0632 protein A
chr13_+_57715051	0.118	NM_198441 NM_001130404 NM_001130405 NM_001130406 NM_001130407	PRR20A PRR20B PRR20C PRR20D PRR20E	proline rich 20A proline rich 20B proline rich 20C proline rich 20D proline rich 20E
chr13_+_113812967	0.112	NM_003891	PROZ	protein Z, vitamin K-dependent plasma glycoprotein
chr1_-_87380008	0.111	NM_004261 NM_203341	SEP15	15 kDa selenoprotein
chr17_+_38137081	0.109		PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr2_-_55496314	0.109	NM_001005369	MTIF2	mitochondrial translational initiation factor 2
chr13_+_57728194	0.109	NM_198441 NM_001130404 NM_001130405 NM_001130406 NM_001130407	PRR20A PRR20B PRR20C PRR20D PRR20E	proline rich 20A proline rich 20B proline rich 20C proline rich 20D proline rich 20E
chr13_+_57734765	0.109	NM_198441 NM_001130404 NM_001130405 NM_001130406 NM_001130407	PRR20A PRR20B PRR20C PRR20D PRR20E	proline rich 20A proline rich 20B proline rich 20C proline rich 20D proline rich 20E
chr13_+_57741330	0.109	NM_198441 NM_001130404 NM_001130405 NM_001130406 NM_001130407	PRR20A PRR20B PRR20C PRR20D PRR20E	proline rich 20A proline rich 20B proline rich 20C proline rich 20D proline rich 20E
chr19_+_38810751	0.108		KCNK6	potassium channel, subfamily K, member 6
chr15_+_90544608	0.108	NM_198526	ZNF710	zinc finger protein 710
chr2_-_60780767	0.108		BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr13_+_57721621	0.108	NM_198441 NM_001130404 NM_001130405 NM_001130406 NM_001130407	PRR20A PRR20B PRR20C PRR20D PRR20E	proline rich 20A proline rich 20B proline rich 20C proline rich 20D proline rich 20E
chr4_+_84457390	0.107	NM_032717	AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr17_+_48351787	0.106	NM_153229	TMEM92	transmembrane protein 92
chrX_-_109561314	0.102	NM_001025580 NM_015365	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr6_+_36916038	0.102	NM_001199159	PI16	peptidase inhibitor 16
chr1_+_203444955	0.100		PRELP	proline/arginine-rich end leucine-rich repeat protein
chr17_-_73874056	0.098		TRIM47	tripartite motif containing 47
chr17_+_38137106	0.094		PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr12_-_42538432	0.094	NM_001099650 NM_173601	GXYLT1	glucoside xylosyltransferase 1
chr6_+_31590468	0.093
chr4_-_74124456	0.092	NM_032217 NM_198889	ANKRD17	ankyrin repeat domain 17
chr18_+_12948004	0.092		SEH1L	SEH1-like (S. cerevisiae)
chr5_-_71803119	0.091	NM_152625	ZNF366	zinc finger protein 366
chr17_-_7166505	0.091	NM_001185022	CLDN7	claudin 7
chrX_+_123095555	0.090	NM_001042750 NM_001042751 NM_006603	STAG2	stromal antigen 2
chr3_+_186648273	0.089	NM_173216 NM_173217	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr22_+_31644314	0.088	NM_001031801 NM_016733	LIMK2	LIM domain kinase 2
chr22_+_39966757	0.086	NM_001003406 NM_021096	CACNA1I	calcium channel, voltage-dependent, T type, alpha 1I subunit
chr1_+_27022521	0.086	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr1_-_226497197	0.085	NM_173083	LIN9	lin-9 homolog (C. elegans)
chr7_-_107204705	0.085	NM_001161520 NM_006348 NM_181733	COG5	component of oligomeric golgi complex 5
chr7_+_138482696	0.084	NM_001085429	TMEM213	transmembrane protein 213
chr5_+_86564044	0.084	NM_002890	RASA1	RAS p21 protein activator (GTPase activating protein) 1
chr17_+_38137115	0.084		PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr11_-_77122877	0.083		PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr6_+_43738177	0.083		VEGFA	vascular endothelial growth factor A
chr4_+_110736636	0.082	NM_018983 NM_032993	GAR1	GAR1 ribonucleoprotein homolog (yeast)
chr1_-_186417855	0.082	NM_022576	PDC	phosducin
chr7_+_21468293	0.081
chr1_+_244624672	0.080	NM_001130957 NM_001242340 NM_173807	C1orf101	chromosome 1 open reading frame 101
chr17_+_635656	0.079	NM_024792	FAM57A	family with sequence similarity 57, member A
chr1_-_226496838	0.077		LIN9	lin-9 homolog (C. elegans)
chr8_-_22926490	0.077	NM_003842 NM_147187	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b
chr2_+_182756665	0.076		SSFA2	sperm specific antigen 2
chrX_+_84498993	0.076	NM_021998	ZNF711	zinc finger protein 711
chr3_+_186648515	0.075		ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr4_+_119809978	0.075	NM_001128933 NM_001128934 NM_133477	SYNPO2	synaptopodin 2
chr12_-_81331449	0.074		LIN7A	lin-7 homolog A (C. elegans)
chrX_-_78622711	0.072		ITM2A	integral membrane protein 2A
chr3_-_192126837	0.072	NM_021032	FGF12	fibroblast growth factor 12
chr1_+_248020607	0.072		TRIM58	tripartite motif containing 58
chr9_+_125796845	0.072	NM_005294	GPR21	G protein-coupled receptor 21
chr12_-_9760481	0.072	NM_002258	KLRB1	killer cell lectin-like receptor subfamily B, member 1
chr16_+_88870214	0.071		CDT1	chromatin licensing and DNA replication factor 1
chr19_+_8117645	0.071	NM_001201359 NM_005624	CCL25	chemokine (C-C motif) ligand 25
chr16_-_2908105	0.071	NM_022119	PRSS22	protease, serine, 22
chr14_-_99947080	0.070		SETD3	SET domain containing 3
chr1_-_223537400	0.070	NM_001037175 NM_017982	SUSD4	sushi domain containing 4
chr18_+_10454542	0.070		APCDD1	adenomatosis polyposis coli down-regulated 1
chrX_-_109561298	0.069		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr17_+_38137053	0.069	NM_002809	PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr2_-_60780404	0.067	NM_018014 NM_022893 NM_138559	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr14_-_21566728	0.067	NM_016423	ZNF219	zinc finger protein 219
chr16_-_30934437	0.067		FBXL19-AS1	FBXL19 antisense RNA 1 (non-protein coding)
chrX_+_123095598	0.066		STAG2	stromal antigen 2
chr4_-_16900028	0.063		LDB2	LIM domain binding 2
chr1_+_19972259	0.062	NM_001204086	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr8_+_30241943	0.061	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr18_-_45935627	0.061		ZBTB7C	zinc finger and BTB domain containing 7C
chr17_+_48133357	0.060		ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr17_-_10741398	0.060	NM_001101387	PIRT	phosphoinositide-interacting regulator of transient receptor potential channels
chr1_-_238054221	0.059	NM_021186	ZP4	zona pellucida glycoprotein 4
chr4_-_74124305	0.058
chr21_+_39628663	0.058	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_2323236	0.057	NM_139022	TSPAN32	tetraspanin 32
chr20_+_44258384	0.057	NM_080753	WFDC10A	WAP four-disulfide core domain 10A
chr15_-_68498373	0.057	NM_001031733 NM_033429	CALML4	calmodulin-like 4
chr6_+_31638727	0.057	NM_021221	LY6G5B	lymphocyte antigen 6 complex, locus G5B
chr1_+_248020481	0.056	NM_015431	TRIM58	tripartite motif containing 58
chr3_+_33155559	0.055		CRTAP	cartilage associated protein
chr16_+_88870185	0.053	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr18_+_12947972	0.053	NM_001013437 NM_031216	SEH1L	SEH1-like (S. cerevisiae)
chr17_+_29058653	0.053		SUZ12P	suppressor of zeste 12 homolog pseudogene
chr16_-_47007567	0.052	NM_005880	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr10_+_104221158	0.051	NM_024789	TMEM180	transmembrane protein 180
chr1_+_87380437	0.050		HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr3_+_47866474	0.050		DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr7_-_127670995	0.050	NM_022143	LRRC4	leucine rich repeat containing 4
chr1_+_110168048	0.049	NM_203404	AMPD2	adenosine monophosphate deaminase 2
chr12_-_49365545	0.049	NM_003394	WNT10B	wingless-type MMTV integration site family, member 10B
chr5_+_175108463	0.048	NM_022304	HRH2	histamine receptor H2
chr14_+_23775970	0.048	NM_001199864 NM_004050 NM_001199839	BCL2L2-PABPN1 BCL2L2	BCL2L2-PABPN1 readthrough BCL2-like 2
chr1_+_44412418	0.048	NM_014652	IPO13	importin 13
chr15_+_75074714	0.047		CSK	c-src tyrosine kinase
chr12_-_117175844	0.047		C12orf49	chromosome 12 open reading frame 49
chr15_-_88799961	0.047	NM_001007156 NM_001012338 NM_001243101 NM_002530	NTRK3	neurotrophic tyrosine kinase, receptor, type 3
chr19_-_7796977	0.046	NM_001244856 NM_198492	CLEC4G	C-type lectin domain family 4, member G
chr18_+_10454620	0.046	NM_153000	APCDD1	adenomatosis polyposis coli down-regulated 1
chr4_-_16900348	0.046	NM_001130834 NM_001290	LDB2	LIM domain binding 2
chr16_-_74734687	0.046	NM_001142497 NM_152649	MLKL	mixed lineage kinase domain-like
chr14_-_64010063	0.046	NM_006246	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr19_+_55795533	0.046	NM_032430	BRSK1	BR serine/threonine kinase 1
chr1_-_26197743	0.045	NM_178422	PAQR7	progestin and adipoQ receptor family member VII
chr1_+_29063443	0.045	NM_001172828	YTHDF2	YTH domain family, member 2
chr16_-_81253974	0.045	NM_001076780 NM_052892	PKD1L2	polycystic kidney disease 1-like 2
chr3_-_66024508	0.045	NM_001033057 NM_004742 NM_015520	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chr18_+_12948010	0.045		SEH1L	SEH1-like (S. cerevisiae)
chr19_-_51071279	0.044	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr3_+_142442855	0.044
chrX_+_2984839	0.044	NM_004042	ARSF	arylsulfatase F
chr10_-_90611675	0.044	NM_144590	ANKRD22	ankyrin repeat domain 22
chr3_-_107809754	0.043	NM_001777 NM_198793	CD47	CD47 molecule
chrX_+_67718623	0.043	NM_001195214 NM_173834	YIPF6	Yip1 domain family, member 6
chr17_+_48133331	0.043	NM_002204 NM_005501	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr6_-_25832268	0.043	NM_005074	SLC17A1	solute carrier family 17 (sodium phosphate), member 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
13.86	2.74e-02	GO:0030501	positive regulation of bone mineralization
2.35	3.06e-02	GO:0048584	positive regulation of response to stimulus
12.70	4.30e-02	GO:0070169	positive regulation of biomineral tissue development

Nothing significant found in compartment category.

Nothing significant found in function category.