Motif ID: FOXA2.p3

Z-value: 1.182


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXA2chr20_-_225650500.866.8e-03Click!


Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_108464344 3.020 NM_015065
EXPH5
exophilin 5
chr2_-_165424993 2.467 GRB14
growth factor receptor-bound protein 14
chr1_+_86889768 2.357 NM_006536
CLCA2
chloride channel accessory 2
chr10_+_118187381 2.346 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr18_+_61254533 2.122 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr15_+_40509628 1.910 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr1_+_152486977 1.459 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr2_+_113885137 1.437 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr8_+_124194751 1.408 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr12_-_53343607 1.347 KRT8
keratin 8
chr20_+_58296264 1.345 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr5_+_140186658 1.327 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr3_+_189349215 1.314 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr1_-_28503454 1.294 NM_000952
NM_001164723
PTAFR

platelet-activating factor receptor

chr10_+_48255223 1.239 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr10_+_82173574 1.176 NM_001243778
NM_001243782
C10orf58

chromosome 10 open reading frame 58

chr8_-_57233240 1.113 NM_138969
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr2_+_113885145 1.111 IL1RN
interleukin 1 receptor antagonist
chr5_+_145316120 1.077 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr10_-_45474210 1.059 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr8_+_31497267 1.041 NM_013962
NRG1
neuregulin 1
chr8_-_57232653 1.032 SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr20_+_9458460 1.021 PLCB4
phospholipase C, beta 4
chr1_+_13911966 0.992 NM_001006624
NM_001006625
PDPN

podoplanin

chr8_-_57232700 0.973 SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chrX_-_133792497 0.959 NM_021796
PLAC1
placenta-specific 1
chr1_+_15478998 0.958 NM_001136216
NM_001136217
TMEM51

transmembrane protein 51

chr5_+_68788118 0.958 NM_002538
OCLN
occludin
chr8_-_15095791 0.913 NM_139167
SGCZ
sarcoglycan, zeta
chrX_+_135614310 0.888 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr2_-_161056762 0.848 ITGB6
integrin, beta 6
chr2_-_161056573 0.816 NM_000888
ITGB6
integrin, beta 6
chr14_-_21567069 0.809 NM_001101672
ZNF219
zinc finger protein 219
chr10_+_24755459 0.781 KIAA1217
KIAA1217
chr5_+_31799030 0.779 NM_178140
PDZD2
PDZ domain containing 2
chr7_-_20256942 0.776 NM_182762
MACC1
metastasis associated in colon cancer 1
chr1_+_15479298 0.749 TMEM51
transmembrane protein 51
chr9_-_112191105 0.724 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr20_+_62795773 0.721 MYT1
myelin transcription factor 1
chr7_-_27135524 0.710 NM_005522
NM_153620
HOXA1

homeobox A1

chr2_+_113875469 0.703 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr8_-_80993009 0.680 NM_001025252
TPD52
tumor protein D52
chr10_-_105845556 0.678 COL17A1
collagen, type XVII, alpha 1
chr1_+_153003677 0.673 NM_003125
SPRR1B
small proline-rich protein 1B
chr5_+_140247767 0.663 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr10_-_129691202 0.631 NM_152311
CLRN3
clarin 3
chr1_-_203320185 0.625 FMOD
fibromodulin
chr11_-_102651321 0.623 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr1_-_203320287 0.616 NM_002023
FMOD
fibromodulin
chr4_-_123542165 0.611 NM_001207006
NM_021803
IL21

interleukin 21

chr4_+_100737980 0.597 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr6_-_134373618 0.594 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr18_-_53071225 0.593 NM_001243232
TCF4
transcription factor 4
chr1_+_43735664 0.590 NM_144626
TMEM125
transmembrane protein 125
chr3_-_190167597 0.585 NM_207316
TMEM207
transmembrane protein 207
chr13_-_75901897 0.582 TBC1D4
TBC1 domain family, member 4
chr17_-_29641087 0.565 EVI2B
ecotropic viral integration site 2B
chr1_+_24645811 0.555 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr17_-_26733185 0.554 NM_001242366
NM_080669
SLC46A1

solute carrier family 46 (folate transporter), member 1

chr12_+_13043955 0.547 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr13_+_78109808 0.543 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr11_+_12308446 0.537 NM_032867
MICALCL
MICAL C-terminal like
chr20_-_43883183 0.523 NM_003064
SLPI
secretory leukocyte peptidase inhibitor
chr8_-_28243941 0.520 NM_018660
ZNF395
zinc finger protein 395
chr14_-_23288912 0.519 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr5_-_142065991 0.519 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr10_-_105845619 0.513 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr21_-_31588242 0.508 NM_199328
CLDN8
claudin 8
chr18_+_55816546 0.504 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr1_-_207095198 0.495 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_29641094 0.483 NM_006495
EVI2B
ecotropic viral integration site 2B
chr19_+_41281281 0.482 NM_006533
MIA
melanoma inhibitory activity
chr11_+_124120422 0.481 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr4_+_169013687 0.470 NM_007193
ANXA10
annexin A10
chr1_+_81771844 0.469 LPHN2
latrophilin 2
chr10_-_123356158 0.454 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr4_-_164534656 0.451 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr12_+_20848288 0.448 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr6_+_144185572 0.447 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr5_+_68800003 0.447 NM_001205255
OCLN
occludin
chr8_+_124194873 0.445 FAM83A
family with sequence similarity 83, member A
chr8_-_142238672 0.436 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr14_-_21493910 0.434 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr12_-_6486522 0.429 NM_001159575
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr2_-_216003068 0.429 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr15_+_68924326 0.427 NM_001190457
CORO2B
coronin, actin binding protein, 2B
chr2_-_69180011 0.424 NM_182536
GKN2
gastrokine 2
chr6_-_31550065 0.424 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr4_+_187148624 0.423 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr14_-_21493858 0.421 NDRG2
NDRG family member 2
chr21_+_39628869 0.420 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_+_196521470 0.420 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr7_-_139763520 0.417 NM_022750
PARP12
poly (ADP-ribose) polymerase family, member 12
chr3_-_48471401 0.417 NM_001130082
PLXNB1
plexin B1
chr1_+_172389827 0.415 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr6_-_155777036 0.413 NM_015718
NOX3
NADPH oxidase 3
chr20_+_30028410 0.410 NM_153324
DEFB123
defensin, beta 123
chr1_+_46640748 0.405 NM_005727
TSPAN1
tetraspanin 1
chr13_-_86373328 0.404 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr11_+_1151578 0.402 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr11_-_46939908 0.402 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr20_-_14318200 0.401 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr1_-_1356823 0.398 NM_001145210
NM_001243535
NM_001243536
ANKRD65


ankyrin repeat domain 65


chr2_-_215896809 0.394 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr20_+_9288446 0.393 NM_000933
PLCB4
phospholipase C, beta 4
chr9_-_125941304 0.391 STRBP
spermatid perinuclear RNA binding protein
chr12_-_71031174 0.386 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr6_+_135502521 0.386 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr9_+_71944240 0.385 NM_004816
FAM189A2
family with sequence similarity 189, member A2
chr10_+_71561687 0.378 COL13A1
collagen, type XIII, alpha 1
chr6_-_32784727 0.375 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr11_+_119205214 0.373 NM_032015
RNF26
ring finger protein 26
chr17_+_72427535 0.369 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr5_-_142065586 0.366 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr11_+_10476665 0.365 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr14_-_31926597 0.365 NM_080664
C14orf126
chromosome 14 open reading frame 126
chr17_-_10452939 0.363 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr6_-_41715078 0.363 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr12_-_52828105 0.359 NM_004693
KRT75
keratin 75
chr14_-_21566728 0.355 NM_016423
ZNF219
zinc finger protein 219
chr2_-_134326030 0.352 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr19_+_15160194 0.352 NM_012114
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr13_+_97874704 0.350 MBNL2
muscleblind-like 2 (Drosophila)
chr6_+_112375277 0.348 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr2_-_71454200 0.347 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr9_-_14722669 0.343 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr6_+_106546736 0.342 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr22_+_21128378 0.342 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr4_-_153303663 0.342 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr10_+_129845806 0.340 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr17_-_39023461 0.328 NM_000223
KRT12
keratin 12
chr3_+_183967414 0.327 NM_014693
NM_032331
ECE2

endothelin converting enzyme 2

chr19_-_45909566 0.327 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr8_-_142264157 0.323 SLC45A4
solute carrier family 45, member 4
chr18_+_56530060 0.322 NM_018181
ZNF532
zinc finger protein 532
chr11_+_6226797 0.318 NM_173525
C11orf42
chromosome 11 open reading frame 42
chr4_+_89378234 0.316 NM_016323
HERC5
hect domain and RLD 5
chr12_-_89746238 0.313 DUSP6
dual specificity phosphatase 6
chr4_-_103245468 0.313 NM_001135148
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr7_-_37024664 0.307 NM_001039459
ELMO1
engulfment and cell motility 1
chr20_+_9198036 0.307 NM_182797
PLCB4
phospholipase C, beta 4
chr20_-_23066828 0.304 NM_012072
CD93
CD93 molecule
chr1_-_231560789 0.302 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr3_-_193096513 0.302 NM_198505
ATP13A5
ATPase type 13A5
chr1_-_153521717 0.300 NM_002960
S100A3
S100 calcium binding protein A3
chr12_-_89745997 0.300 DUSP6
dual specificity phosphatase 6
chr8_-_17579729 0.297 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr11_-_104905849 0.294 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr2_+_196521851 0.294 NM_020342
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr19_+_45909466 0.294 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr7_-_25268057 0.290 NM_022150
NPVF
neuropeptide VF precursor
chr5_-_158637060 0.289 NM_001199380
RNF145
ring finger protein 145
chrX_-_33357725 0.289 NM_000109
DMD
dystrophin
chr12_-_71148331 0.287 PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_+_68788387 0.287 NM_001205254
OCLN
occludin
chr3_-_112564789 0.287 NM_001008784
NM_001199215
CD200R1L

CD200 receptor 1-like

chr3_-_193272587 0.287 NM_032279
ATP13A4
ATPase type 13A4
chr1_-_67266930 0.285 NM_005478
INSL5
insulin-like 5
chr17_-_46655544 0.282 NM_024015
HOXB4
homeobox B4
chr6_+_134758840 0.279 LOC154092
uncharacterized LOC154092
chr2_+_242127923 0.277 NM_001001666
NM_001001891
ANO7

anoctamin 7

chr3_+_97887543 0.275 NM_001005515
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr20_+_9494995 0.275 NM_001199897
NM_012261
LAMP5

lysosomal-associated membrane protein family, member 5

chr11_+_10482677 0.274 NM_001172430
AMPD3
adenosine monophosphate deaminase 3
chr3_-_123339423 0.268 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr3_+_52811601 0.267 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr7_+_136553398 0.267 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr10_+_91498724 0.266 KIF20B
kinesin family member 20B
chr2_-_170430312 0.263 NM_024622
FASTKD1
FAST kinase domains 1
chr10_-_21435487 0.261 NM_001010896
NM_001177483
C10orf113

chromosome 10 open reading frame 113

chr11_-_119999516 0.261 TRIM29
tripartite motif containing 29
chr12_-_71148383 0.260 NM_130846
NM_001207016
PTPRR

protein tyrosine phosphatase, receptor type, R

chr3_+_70048882 0.260


chr1_-_109935869 0.259 NM_001205228
SORT1
sortilin 1
chr11_+_62186506 0.258 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr12_-_71148063 0.258 PTPRR
protein tyrosine phosphatase, receptor type, R
chr21_-_39956823 0.258 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr4_+_140586921 0.258 NM_001204366
NM_001204367
NM_001204368
NM_002413
MGST2



microsomal glutathione S-transferase 2



chr3_+_97851540 0.256 NM_001005338
OR5H1
olfactory receptor, family 5, subfamily H, member 1
chr11_-_64377332 0.256


chr21_-_40033617 0.253 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr6_+_135502445 0.253 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr10_-_98031154 0.251 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_+_160394946 0.251 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr1_+_84874033 0.251 NM_058248
DNASE2B
deoxyribonuclease II beta
chr6_-_29012951 0.250 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr1_+_86934525 0.248 NM_001285
CLCA1
chloride channel accessory 1
chr2_+_11674241 0.248 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr21_+_39628663 0.246 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_-_16509106 0.244 NM_019000
FAM134B
family with sequence similarity 134, member B
chr7_-_151071696 0.243


chrX_+_24167728 0.243 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chrX_-_33229428 0.242 NM_004006
DMD
dystrophin
chr5_-_78281688 0.242 NM_198709
ARSB
arylsulfatase B
chr4_+_15429628 0.239 NM_031911
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr22_+_41074994 0.238 NM_005297
MCHR1
melanin-concentrating hormone receptor 1
chr6_+_26251826 0.238 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr11_-_107582733 0.237 NM_003063
SLN
sarcolipin
chrX_-_10851808 0.235 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr2_-_27579277 0.235 GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.99 8.73e-03 GO:0006820 anion transport
3.80 3.04e-02 GO:0015711 organic anion transport
4.92 4.85e-02 GO:0008206 bile acid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.47 1.68e-04 GO:0005576 extracellular region
1.62 2.47e-04 GO:0005887 integral to plasma membrane
1.59 5.87e-04 GO:0031226 intrinsic to plasma membrane
1.38 4.83e-03 GO:0044459 plasma membrane part
1.54 2.02e-02 GO:0044421 extracellular region part
1.19 4.31e-02 GO:0016021 integral to membrane
1.23 4.41e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.60 3.09e-02 GO:0008509 anion transmembrane transporter activity