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Motif ID: FOXL1.p2

Z-value: 1.034

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_113739203	1.574	NM_001127493	ANK2	ankyrin 2, neuronal
chr2_+_189839078	0.901	NM_000090	COL3A1	collagen, type III, alpha 1
chr12_+_60083125	0.804	NM_004731	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr7_+_45933096	0.760
chr2_+_152214105	0.577	NM_007115	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr1_+_163038564	0.548	NM_005613	RGS4	regulator of G-protein signaling 4
chr4_-_156787377	0.518	NM_017419	ACCN5	amiloride-sensitive cation channel 5, intestinal
chr1_+_162602308	0.506		DDR2	discoidin domain receptor tyrosine kinase 2
chr10_+_94594469	0.504	NM_001013848	EXOC6	exocyst complex component 6
chr1_+_162602198	0.502	NM_001014796 NM_006182	DDR2	discoidin domain receptor tyrosine kinase 2
chr5_-_111091947	0.448	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr1_-_183622447	0.421	NM_203454	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr1_+_163038395	0.400	NM_001102445	RGS4	regulator of G-protein signaling 4
chr1_-_149889362	0.382	NM_014849	SV2A	synaptic vesicle glycoprotein 2A
chr10_+_96522457	0.359	NM_000769	CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
chr4_+_113970784	0.353	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr2_-_163008913	0.336	NM_002054	GCG	glucagon
chr15_-_90349819	0.331		ANPEP	alanyl (membrane) aminopeptidase
chr4_+_70916158	0.324	NM_002159	HTN1	histatin 1
chr17_-_67240955	0.321	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr1_-_19186154	0.316	NM_152232	TAS1R2	taste receptor, type 1, member 2
chr10_+_225932	0.314	NM_001202467 NM_001202468	ZMYND11	zinc finger, MYND-type containing 11
chr8_+_104831415	0.302	NM_014677	RIMS2	regulating synaptic membrane exocytosis 2
chr17_+_65936590	0.299		BPTF	bromodomain PHD finger transcription factor
chr2_-_188419049	0.299		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr13_-_38172862	0.286	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr2_+_24807345	0.285	NM_003743 NM_147223 NM_147233	NCOA1	nuclear receptor coactivator 1
chr1_-_57045129	0.279		PPAP2B	phosphatidic acid phosphatase type 2B
chr2_-_163099877	0.277	NM_004460	FAP	fibroblast activation protein, alpha
chr12_+_50869531	0.270		LARP4	La ribonucleoprotein domain family, member 4
chr6_+_144612872	0.267	NM_007124	UTRN	utrophin
chr12_-_91573264	0.255	NM_133503	DCN	decorin
chr4_+_71062241	0.255	NM_017855	ODAM	odontogenic, ameloblast asssociated
chr10_+_69869249	0.253	NM_032578	MYPN	myopalladin
chr17_-_67138013	0.244	NM_080284	ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6
chr3_-_12941547	0.242		IQSEC1	IQ motif and Sec7 domain 1
chr8_-_93029864	0.240	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_26724748	0.238		ADRA1A	adrenergic, alpha-1A-, receptor
chr12_-_102591547	0.236	NM_002674	PMCH	pro-melanin-concentrating hormone
chr1_+_65730423	0.234	NM_014787	DNAJC6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_-_39033981	0.232	NM_024943	TMEM156	transmembrane protein 156
chr2_-_200325200	0.231		SATB2	SATB homeobox 2
chr5_+_139889635	0.231
chr5_+_65372744	0.228		ERBB2IP	erbb2 interacting protein
chr3_+_42727010	0.228	NM_152393	KBTBD5	kelch repeat and BTB (POZ) domain containing 5
chr5_-_32388687	0.228		ZFR	zinc finger RNA binding protein
chr3_-_112359863	0.223		CCDC80	coiled-coil domain containing 80
chr1_+_145524989	0.217	NM_003637	ITGA10	integrin, alpha 10
chr2_-_55199894	0.216
chr7_+_128312345	0.213	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr3_-_52713728	0.212	NM_018165 NM_181042	PBRM1	polybromo 1
chr5_+_92918924	0.212	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr14_-_81405883	0.209	NM_152446	CEP128	centrosomal protein 128kDa
chr1_-_57045214	0.208		PPAP2B	phosphatidic acid phosphatase type 2B
chr1_+_114493766	0.207	NM_198269	HIPK1	homeodomain interacting protein kinase 1
chr8_+_98703361	0.206		MTDH	metadherin
chr17_-_8063946	0.205		VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr13_+_76334796	0.196	NM_015842	LMO7	LIM domain 7
chr9_+_96846710	0.195	NM_001253829 NM_152422	PTPDC1	protein tyrosine phosphatase domain containing 1
chr15_+_93443559	0.193		CHD2	chromodomain helicase DNA binding protein 2
chr17_-_41276112	0.192	NM_007298	BRCA1	breast cancer 1, early onset
chr2_-_190044330	0.192	NM_000393	COL5A2	collagen, type V, alpha 2
chr5_+_161277702	0.188	NM_001127648	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr16_-_11370305	0.188	NM_002762	PRM2	protamine 2
chr1_+_168545710	0.187	NM_002995	XCL1	chemokine (C motif) ligand 1
chr2_-_188419185	0.186	NM_001032281 NM_006287	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr5_+_156696351	0.180	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chrX_-_15332680	0.178	NM_001012428	ASB11	ankyrin repeat and SOCS box containing 11
chr5_-_94224601	0.175		MCTP1	multiple C2 domains, transmembrane 1
chr6_+_147527102	0.171		STXBP5	syntaxin binding protein 5 (tomosyn)
chr3_-_100712248	0.171	NM_015429	ABI3BP	ABI family, member 3 (NESH) binding protein
chr1_+_163038934	0.170	NM_001113381	RGS4	regulator of G-protein signaling 4
chr18_-_40857245	0.166	NM_020783	SYT4	synaptotagmin IV
chr1_+_115572414	0.166	NM_000549	TSHB	thyroid stimulating hormone, beta
chr2_-_100046262	0.165		REV1	REV1 homolog (S. cerevisiae)
chr11_+_20620945	0.164	NM_004211	SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr8_-_62602285	0.164	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr2_-_158300517	0.162	NM_004288	CYTIP	cytohesin 1 interacting protein
chr3_-_151102536	0.161	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr9_-_74675498	0.160	NM_001128618	C9orf57	chromosome 9 open reading frame 57
chr3_+_12392993	0.158	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr12_+_32654976	0.157	NM_139241	FGD4	FYVE, RhoGEF and PH domain containing 4
chr6_+_20534686	0.157	NM_017774	CDKAL1	CDK5 regulatory subunit associated protein 1-like 1
chr8_-_95907423	0.155	NM_057749	CCNE2	cyclin E2
chr3_-_112359962	0.154	NM_199511 NM_199512	CCDC80	coiled-coil domain containing 80
chr18_-_56296188	0.153	NM_052947	ALPK2	alpha-kinase 2
chr17_+_35732927	0.152	NM_173625	C17orf78	chromosome 17 open reading frame 78
chr9_-_21482311	0.151	NM_176891	IFNE	interferon, epsilon
chrX_+_36065052	0.150	NM_173695	CXorf59	chromosome X open reading frame 59
chr1_-_149900143	0.149	NM_005850	SF3B4	splicing factor 3b, subunit 4, 49kDa
chr5_+_140792507	0.148	NM_018913 NM_032090	PCDHGA10	protocadherin gamma subfamily A, 10
chr2_+_170662044	0.148		SSB	Sjogren syndrome antigen B (autoantigen La)
chr3_+_135741576	0.147	NM_181897	PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr17_-_29648631	0.147	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chrX_+_139791923	0.142		RP1-177G6.2	uncharacterized LOC286411
chr8_+_105352050	0.142	NM_030788	TM7SF4	transmembrane 7 superfamily member 4
chr20_+_44330654	0.141	NM_172005	WFDC13	WAP four-disulfide core domain 13
chr9_+_111624545	0.141	NM_006687	ACTL7A	actin-like 7A
chr8_+_17822093	0.141		PCM1	pericentriolar material 1
chr16_-_20364029	0.138	NM_001008389 NM_003361	UMOD	uromodulin
chr6_-_116447225	0.138	NM_000493	COL10A1	collagen, type X, alpha 1
chr9_-_95186559	0.137	NM_005014	OMD	osteomodulin
chr2_-_40739570	0.135	NM_001112802	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr19_-_14169970	0.135	NM_001145028	PALM3	paralemmin 3
chr12_-_91505541	0.134	NM_002345	LUM	lumican
chr1_-_86043932	0.134	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr3_-_42843217	0.134
chr4_+_146031528	0.131		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr2_+_85766286	0.131		MAT2A	methionine adenosyltransferase II, alpha
chr19_+_48828627	0.130	NM_001425	EMP3	epithelial membrane protein 3
chr5_+_140739589	0.130	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr4_+_88720701	0.129	NM_004967	IBSP	integrin-binding sialoprotein
chr3_+_157154579	0.127	NM_002852	PTX3	pentraxin 3, long
chr17_+_18647325	0.126	NM_031456	FBXW10	F-box and WD repeat domain containing 10
chr5_-_32388595	0.125		ZFR	zinc finger RNA binding protein
chr14_+_21359542	0.125	NM_002935	RNASE3	ribonuclease, RNase A family, 3
chr11_+_5474637	0.124	NM_001004754	OR51I2	olfactory receptor, family 51, subfamily I, member 2
chr9_-_21142143	0.124	NM_002177	IFNW1	interferon, omega 1
chr3_-_123339178	0.124		MYLK	myosin light chain kinase
chr10_+_57358749	0.123	NM_001190478	MTRNR2L5	MT-RNR2-like 5
chrX_-_106960268	0.122	NM_004089	TSC22D3	TSC22 domain family, member 3
chr17_-_19651586	0.122	NM_000691	ALDH3A1	aldehyde dehydrogenase 3 family, member A1
chr11_+_65266642	0.122
chr14_+_23352430	0.122	NM_173527	REM2	RAS (RAD and GEM)-like GTP binding 2
chr4_+_74269971	0.121	NM_000477	ALB	albumin
chr14_-_20774129	0.121	NM_138376	TTC5	tetratricopeptide repeat domain 5
chr7_-_92855780	0.119	NM_001039372	HEPACAM2	HEPACAM family member 2
chr9_-_100700422	0.119	NM_197978	HEMGN	hemogen
chr3_+_115342150	0.119	NM_001130064 NM_002045	GAP43	growth associated protein 43
chr3_-_112564789	0.118	NM_001008784 NM_001199215	CD200R1L	CD200 receptor 1-like
chr2_-_37297372	0.117		HEATR5B	HEAT repeat containing 5B
chr18_-_52625278	0.117	NM_001143829	CCDC68	coiled-coil domain containing 68
chr1_-_153518265	0.116	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr4_-_74088773	0.116		ANKRD17	ankyrin repeat domain 17
chrX_-_21776158	0.115	NM_014332	SMPX	small muscle protein, X-linked
chr13_+_50589389	0.115	NM_173605 NM_199464	TRIM13 KCNRG	tripartite motif containing 13 potassium channel regulator
chr12_+_1726221	0.114	NM_030775	WNT5B	wingless-type MMTV integration site family, member 5B
chr19_+_48828820	0.114		EMP3	epithelial membrane protein 3
chr1_+_198608136	0.113	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr11_-_71746966	0.113
chrX_+_37639306	0.113		CYBB	cytochrome b-245, beta polypeptide
chr16_+_4430878	0.113		VASN	vasorin
chr4_+_88754120	0.113	NM_001184695 NM_001184696 NM_001184697 NM_020203	MEPE	matrix extracellular phosphoglycoprotein
chr8_-_82359620	0.113	NM_002677	PMP2	peripheral myelin protein 2
chr11_-_102826433	0.111	NM_002427	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr3_-_151058439	0.111	NM_176876	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr12_-_46633551	0.111		SLC38A1	solute carrier family 38, member 1
chr1_+_11249344	0.110	NM_021146	ANGPTL7	angiopoietin-like 7
chrX_-_19688991	0.109	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr11_+_33363104	0.109		HIPK3	homeodomain interacting protein kinase 3
chr2_+_233709104	0.108		GIGYF2	GRB10 interacting GYF protein 2
chr6_-_87804773	0.108	NM_000735 NM_001252383	CGA	glycoprotein hormones, alpha polypeptide
chr7_+_107110501	0.108	NM_005295	GPR22	G protein-coupled receptor 22
chr4_+_120056938	0.108	NM_016599	MYOZ2	myozenin 2
chr15_-_55652777	0.107		CCPG1	cell cycle progression 1
chr3_-_149095517	0.107	NM_014220	TM4SF1	transmembrane 4 L six family member 1
chr5_+_55147206	0.107	NM_001242637 NM_001242638 NM_139017	IL31RA	interleukin 31 receptor A
chr6_-_139695784	0.106	NM_006079	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr10_+_5488521	0.106	NM_005863	NET1	neuroepithelial cell transforming 1
chr14_+_92788924	0.105	NM_153648	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr9_-_13250313	0.105	NM_003829	MPDZ	multiple PDZ domain protein
chr9_+_125281418	0.104	NM_001004452	OR1J4	olfactory receptor, family 1, subfamily J, member 4
chr1_+_41204509	0.104		NFYC	nuclear transcription factor Y, gamma
chr2_-_166060552	0.104	NM_001081676 NM_001081677 NM_006922	SCN3A	sodium channel, voltage-gated, type III, alpha subunit
chr1_-_168513201	0.104	NM_003175	XCL1 XCL2	chemokine (C motif) ligand 1 chemokine (C motif) ligand 2
chr5_-_94417185	0.103		MCTP1	multiple C2 domains, transmembrane 1
chr15_+_93443418	0.102	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr17_-_54893249	0.102	NM_001085430	C17orf67	chromosome 17 open reading frame 67
chr17_+_76000248	0.102	NM_001142640 NM_018996	TNRC6C	trinucleotide repeat containing 6C
chr12_+_54422193	0.102	NM_004503	HOXC6	homeobox C6
chr13_-_24007822	0.101	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr17_-_9929567	0.101	NM_001130831	GAS7	growth arrest-specific 7
chr2_+_33661392	0.100	NM_170672	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_+_39408472	0.100	NM_175737	KLB	klotho beta
chr10_+_91498724	0.100		KIF20B	kinesin family member 20B
chr3_-_165555252	0.099	NM_000055	BCHE	butyrylcholinesterase
chr2_+_202671197	0.099	NM_139158	CDK15	cyclin-dependent kinase 15
chr7_+_80267922	0.099		CD36	CD36 molecule (thrombospondin receptor)
chr2_+_27301434	0.099	NM_007046	EMILIN1	elastin microfibril interfacer 1
chr17_+_37821598	0.098	NM_003673	TCAP	titin-cap (telethonin)
chr22_+_29449877	0.098		ZNRF3	zinc and ring finger 3
chr10_+_83637442	0.098	NM_001165973	NRG3	neuregulin 3
chr2_-_200329810	0.098	NM_001172517	SATB2	SATB homeobox 2
chr1_-_155948934	0.097		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chrX_-_138287180	0.097	NM_001139498 NM_001139500 NM_001139501	FGF13	fibroblast growth factor 13
chr7_-_80141241	0.097	NM_001102386	GNAT3	guanine nucleotide binding protein, alpha transducing 3
chr11_+_113845796	0.097	NM_000869 NM_213621	HTR3A	5-hydroxytryptamine (serotonin) receptor 3A
chr3_-_149095333	0.096		TM4SF1	transmembrane 4 L six family member 1
chrX_+_57618268	0.096	NM_007157	ZXDB	zinc finger, X-linked, duplicated B
chr5_+_126859157	0.096		PRRC1	proline-rich coiled-coil 1
chr12_-_81763127	0.096	NM_001220479 NM_001220480	PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr10_+_102121371	0.096		SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr14_-_106714594	0.095
chr5_+_53751430	0.095	NM_006308	HSPB3	heat shock 27kDa protein 3
chr9_+_5510544	0.094	NM_025239	PDCD1LG2	programmed cell death 1 ligand 2
chr12_-_91452130	0.094	NM_007035	KERA	keratocan
chr1_+_152943127	0.093	NM_173080	SPRR4	small proline-rich protein 4
chr7_-_44180911	0.093	NM_021223	MYL7	myosin, light chain 7, regulatory
chr5_-_32403310	0.093		ZFR	zinc finger RNA binding protein
chr22_+_40322609	0.093		GRAP2	GRB2-related adaptor protein 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.17	1.24e-05	GO:0003012	muscle system process
3.24	2.29e-05	GO:0006936	muscle contraction
1.75	3.21e-03	GO:0048584	positive regulation of response to stimulus
1.23	6.45e-03	GO:0032501	multicellular organismal process
2.30	8.24e-03	GO:0061061	muscle structure development
2.20	2.28e-02	GO:0050778	positive regulation of immune response
2.50	2.34e-02	GO:0007517	muscle organ development
2.84	3.17e-02	GO:0042692	muscle cell differentiation
6.49	3.36e-02	GO:0030239	myofibril assembly
2.32	4.82e-02	GO:0002253	activation of immune response

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.64	8.50e-10	GO:0005576	extracellular region
1.90	1.69e-08	GO:0044421	extracellular region part
3.46	1.35e-05	GO:0043292	contractile fiber
1.85	1.64e-05	GO:0005615	extracellular space
3.53	1.76e-05	GO:0030016	myofibril
1.92	1.19e-04	GO:0030054	cell junction
3.32	1.91e-04	GO:0044449	contractile fiber part
3.30	1.19e-03	GO:0030017	sarcomere
1.25	3.19e-03	GO:0071944	cell periphery
2.12	3.42e-03	GO:0005578	proteinaceous extracellular matrix
1.98	6.00e-03	GO:0031012	extracellular matrix
1.24	9.84e-03	GO:0005886	plasma membrane
6.63	1.43e-02	GO:0032982	myosin filament
1.32	4.06e-02	GO:0044459	plasma membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.33	1.05e-04	GO:0003779	actin binding
1.85	3.37e-03	GO:0008092	cytoskeletal protein binding
1.16	7.08e-03	GO:0005515	protein binding