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Motif ID: FOXP3.p2

Z-value: 0.922

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_140213968	2.122	NM_018910 NM_031852	PCDHA7	protocadherin alpha 7
chr6_-_11779279	1.745	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr4_+_40198526	1.589	NM_004310	RHOH	ras homolog gene family, member H
chr15_+_43885251	1.199	NM_020990	CKMT1B CKMT1A	creatine kinase, mitochondrial 1B creatine kinase, mitochondrial 1A
chr1_+_46646199	1.118		TSPAN1	tetraspanin 1
chrX_+_105412297	0.949	NM_001171020 NM_152423	MUM1L1	melanoma associated antigen (mutated) 1-like 1
chr1_-_153029987	0.888	NM_005988	SPRR2A	small proline-rich protein 2A
chr7_+_26400503	0.738	NM_001199837	SNX10	sorting nexin 10
chr1_-_153067000	0.729	NM_001024209	SPRR2E	small proline-rich protein 2E
chr8_-_139926235	0.696	NM_152888	COL22A1	collagen, type XXII, alpha 1
chr8_+_124194751	0.675	NM_032899 NM_207006	FAM83A	family with sequence similarity 83, member A
chr1_-_153588789	0.612	NM_020672	S100A14	S100 calcium binding protein A14
chr9_+_12693385	0.569	NM_000550	TYRP1	tyrosinase-related protein 1
chr6_+_47666288	0.531	NM_153838	GPR115	G protein-coupled receptor 115
chr2_-_215896809	0.526	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr1_+_156030965	0.486	NM_020387	RAB25	RAB25, member RAS oncogene family
chr22_-_39636906	0.442	NM_033016	PDGFB	platelet-derived growth factor beta polypeptide
chr1_+_158223926	0.425	NM_001763	CD1A	CD1a molecule
chr1_-_16539103	0.419	NM_153213	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19
chr3_-_196911001	0.419	NM_001204387 NM_001204388	DLG1	discs, large homolog 1 (Drosophila)
chr1_-_153044083	0.417	NM_001017418	SPRR2B	small proline-rich protein 2B
chr11_+_34654010	0.415	NM_001206616	EHF	ets homologous factor
chr6_+_144185572	0.405	NM_001013623	C6orf94	chromosome 6 open reading frame 94
chr4_+_88896801	0.401	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr6_-_25874439	0.398	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr6_+_116782555	0.385	NM_001010919	FAM26F	family with sequence similarity 26, member F
chr3_-_172241060	0.376	NM_001190943 NM_001190942 NM_003810	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
chr3_-_121264780	0.371	NM_199420	POLQ	polymerase (DNA directed), theta
chr17_-_29641087	0.370		EVI2B	ecotropic viral integration site 2B
chr6_-_136847078	0.361	NM_001198608 NM_001198609 NM_001198611	MAP7	microtubule-associated protein 7
chr12_-_52914080	0.354	NM_000424	KRT5	keratin 5
chr11_-_51412447	0.350	NM_001005272	OR4A5	olfactory receptor, family 4, subfamily A, member 5
chr7_+_143701021	0.345	NM_001005281	OR6B1	olfactory receptor, family 6, subfamily B, member 1
chr3_+_186560478	0.333		ADIPOQ	adiponectin, C1Q and collagen domain containing
chr17_-_29641094	0.326	NM_006495	EVI2B	ecotropic viral integration site 2B
chr18_+_29027731	0.317	NM_001944	DSG3	desmoglein 3
chr3_+_186560462	0.314	NM_001177800 NM_004797	ADIPOQ	adiponectin, C1Q and collagen domain containing
chr6_+_54711568	0.302	NM_001010872	FAM83B	family with sequence similarity 83, member B
chr6_+_132859426	0.300	NM_175057	TAAR9	trace amine associated receptor 9 (gene/pseudogene)
chr12_+_10163225	0.298	NM_001129998 NM_205852	CLEC12B	C-type lectin domain family 12, member B
chr19_-_6720585	0.292	NM_000064	C3	complement component 3
chr1_-_93399531	0.280
chr12_-_8219001	0.278		C3AR1	complement component 3a receptor 1
chr1_-_152552962	0.276	NM_032563	LCE3D	late cornified envelope 3D
chr16_+_15068921	0.259		PDXDC1	pyridoxal-dependent decarboxylase domain containing 1
chr4_-_123377471	0.259	NM_000586	IL2	interleukin 2
chr11_-_7847518	0.259	NM_153445	OR5P3	olfactory receptor, family 5, subfamily P, member 3
chrX_-_117119282	0.258	NM_001168299	KLHL13	kelch-like 13 (Drosophila)
chr2_-_75796847	0.251	NM_032181	FAM176A	family with sequence similarity 176, member A
chr14_-_35344852	0.246	NM_013448 NM_182648	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr12_+_48516428	0.244	NM_001166687 NM_001166688	PFKM	phosphofructokinase, muscle
chr1_+_207627614	0.242	NM_001006658 NM_001877	CR2	complement component (3d/Epstein Barr virus) receptor 2
chr6_-_167797917	0.239	NM_004610	TCP10	t-complex 10 homolog (mouse)
chr4_+_88896899	0.230		SPP1	secreted phosphoprotein 1
chr4_+_88896838	0.228		SPP1	secreted phosphoprotein 1
chr3_-_53164417	0.226	NM_052859	RFT1	RFT1 homolog (S. cerevisiae)
chr1_-_207095198	0.223	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr8_-_7681359	0.223	NM_152250 NM_001040703	DEFB105A DEFB105B	defensin, beta 105A defensin, beta 105B
chr8_+_7345190	0.220	NM_152250 NM_001040703	DEFB105A DEFB105B	defensin, beta 105A defensin, beta 105B
chr11_+_117947785	0.215		TMPRSS4	transmembrane protease, serine 4
chrX_+_8432870	0.213	NM_001001888	VCX3B VCX3A	variable charge, X-linked 3B variable charge, X-linked 3A
chr11_-_85437457	0.211	NM_206927 NM_206928	SYTL2	synaptotagmin-like 2
chr10_-_45474210	0.210	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr6_-_29323971	0.205	NM_030876	OR5V1	olfactory receptor, family 5, subfamily V, member 1
chr10_-_118680978	0.205		KIAA1598	KIAA1598
chr2_+_198570027	0.204	NM_138395	MARS2	methionyl-tRNA synthetase 2, mitochondrial
chr2_-_113594325	0.204	NM_000576	IL1B	interleukin 1, beta
chr17_+_51900238	0.203	NM_032559	KIF2B	kinesin family member 2B
chr2_+_65663812	0.202		FLJ16124	FLJ16124 protein
chr14_+_21498344	0.201	NM_173846	TPPP2	tubulin polymerization-promoting protein family member 2
chr12_+_105153258	0.199		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr1_+_158149736	0.199	NM_001766	CD1D	CD1d molecule
chr1_+_24645914	0.199	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr6_-_32497925	0.197	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr4_+_86699846	0.195	NM_001042669	ARHGAP24	Rho GTPase activating protein 24
chr22_+_21128378	0.194	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr21_+_43710190	0.192		ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr12_-_8218930	0.190	NM_004054	C3AR1	complement component 3a receptor 1
chr11_+_117947726	0.176	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr8_+_32579350	0.176	NM_001159996	NRG1	neuregulin 1
chrX_-_49965003	0.175	NM_139289	AKAP4	A kinase (PRKA) anchor protein 4
chrM_+_4770	0.174
chr14_+_21510384	0.174	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr5_+_34687663	0.168	NM_001145523	RAI14	retinoic acid induced 14
chr1_+_24645811	0.167	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr5_+_126984712	0.164	NM_001048252	CTXN3	cortexin 3
chr11_+_10476665	0.164	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr2_+_191002485	0.161	NM_001042521	C2orf88	chromosome 2 open reading frame 88
chr1_-_150738232	0.160		CTSS	cathepsin S
chr15_+_42131010	0.158	NM_001114633	PLA2G4B	phospholipase A2, group IVB (cytosolic)
chr3_+_97868169	0.157	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr11_-_8892909	0.155		ST5	suppression of tumorigenicity 5
chr1_-_161147757	0.155	NM_001199873 NM_001199874 NM_003779	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr3_+_132036210	0.150	NM_001099 NM_001134194	ACPP	acid phosphatase, prostate
chr4_+_86699858	0.150		ARHGAP24	Rho GTPase activating protein 24
chr4_+_41540320	0.150		LIMCH1	LIM and calponin homology domains 1
chr6_+_74104284	0.148	NM_018665	DDX43	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr3_+_130569368	0.147	NM_001199180 NM_001199181 NM_001199182	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr6_+_106546736	0.147	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr10_-_113933517	0.146		GPAM	glycerol-3-phosphate acyltransferase, mitochondrial
chr12_-_50616425	0.144	NM_001113547	LIMA1	LIM domain and actin binding 1
chr1_-_150738292	0.142	NM_001199739 NM_004079	CTSS	cathepsin S
chr8_-_17555158	0.140	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr3_+_132036276	0.138		ACPP	acid phosphatase, prostate
chr2_+_1418179	0.133	NM_175721 NM_175722	TPO	thyroid peroxidase
chr6_+_71136141	0.130	NM_001162529	FAM135A	family with sequence similarity 135, member A
chr12_+_53497273	0.127	NM_003578	SOAT2	sterol O-acyltransferase 2
chr11_-_120008848	0.127	NM_012101	TRIM29	tripartite motif containing 29
chr12_-_48963802	0.126	NM_002289	LALBA	lactalbumin, alpha-
chr16_+_2867227	0.126		PRSS21	protease, serine, 21 (testisin)
chr17_-_3337134	0.126	NM_003554	OR1E2	olfactory receptor, family 1, subfamily E, member 2
chr5_+_121465214	0.125	NM_207317	ZNF474	zinc finger protein 474
chr7_-_143956720	0.125	NM_001005328	OR2A7	olfactory receptor, family 2, subfamily A, member 7
chr20_+_9288446	0.124	NM_000933	PLCB4	phospholipase C, beta 4
chr15_+_77287688	0.124		PSTPIP1	proline-serine-threonine phosphatase interacting protein 1
chr13_+_96085852	0.123	NM_001160100 NM_182848	CLDN10	claudin 10
chr1_-_153348057	0.122	NM_005621	S100A12	S100 calcium binding protein A12
chr9_+_130911731	0.121	NM_005564	LCN2	lipocalin 2
chr8_-_86253863	0.119	NM_001164830	CA1	carbonic anhydrase I
chr4_-_103245468	0.117	NM_001135148	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr4_+_41540187	0.117		LIMCH1	LIM and calponin homology domains 1
chr12_+_50024326	0.116	NM_001031698	PRPF40B	PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr13_+_43355685	0.116	NM_182508	C13orf30	chromosome 13 open reading frame 30
chr6_+_139349818	0.116	NM_021243	C6orf115	chromosome 6 open reading frame 115
chr16_+_2867163	0.115	NM_006799 NM_144956 NM_144957	PRSS21	protease, serine, 21 (testisin)
chr1_+_31883020	0.114	NM_001199037	SERINC2	serine incorporator 2
chr3_-_51533996	0.112	NM_001171904 NM_014703	VPRBP	Vpr (HIV-1) binding protein
chr20_-_3644045	0.112	NM_022139 NM_145762	GFRA4	GDNF family receptor alpha 4
chr5_+_140566655	0.109	NM_019119	PCDHB9	protocadherin beta 9
chr19_-_45579687	0.108	NM_145288	ZNF296	zinc finger protein 296
chrX_-_117107700	0.107	NM_033495 NM_001168300	KLHL13	kelch-like 13 (Drosophila)
chrX_-_109683457	0.107	NM_001171689	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_+_2938045	0.107	NM_080431	ACTRT2	actin-related protein T2
chr4_-_89978117	0.106	NM_014883	FAM13A	family with sequence similarity 13, member A
chr17_+_28268622	0.105	NM_198529	EFCAB5	EF-hand calcium binding domain 5
chr6_+_88117689	0.103	NM_001031743	C6orf165	chromosome 6 open reading frame 165
chr12_-_10562744	0.102	NM_001199805	KLRC4-KLRK1	KLRC4-KLRK1 readthrough
chr8_-_81787015	0.101	NM_001033723	ZNF704	zinc finger protein 704
chr6_-_24383519	0.100	NM_001195610	DCDC2	doublecortin domain containing 2
chrX_-_106362050	0.098	NM_001171080 NM_018301	RBM41	RNA binding motif protein 41
chr16_-_55989942	0.097	NM_001190158	CES5A	carboxylesterase 5A
chrX_+_102965836	0.097	NM_182541	TMEM31	transmembrane protein 31
chr21_-_33957746	0.096	NM_144659	TCP10L	t-complex 10 (mouse)-like
chr5_+_61874561	0.095	NM_181506	LRRC70	leucine rich repeat containing 70
chr19_+_4278597	0.095	NM_020209	SHD	Src homology 2 domain containing transforming protein D
chr8_+_107738239	0.094	NM_001198534 NM_001198535	OXR1	oxidation resistance 1
chrX_-_101112548	0.094	NM_032946	NXF5	nuclear RNA export factor 5
chr11_-_72380107	0.093	NM_001146209	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr6_+_158733691	0.092	NM_001007466 NM_020245	TULP4	tubby like protein 4
chr3_-_57312979	0.090	NM_130387	ASB14	ankyrin repeat and SOCS box containing 14
chr7_-_142659397	0.086		KEL	Kell blood group, metallo-endopeptidase
chr3_-_64672285	0.085		ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_-_121944485	0.084	NM_001024613 NM_001160264	FEZF1	FEZ family zinc finger 1
chr11_-_113345841	0.084	NM_000795 NM_016574	DRD2	dopamine receptor D2
chr17_-_3301703	0.083	NM_003553	OR1E1	olfactory receptor, family 1, subfamily E, member 1
chr17_-_39661803	0.082	NM_002274 NM_153490	KRT13	keratin 13
chr1_-_204459445	0.082	NM_002646	PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide
chr4_+_71200670	0.082	NM_033122	CABS1	calcium-binding protein, spermatid-specific 1
chr1_-_120935893	0.082		FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr22_+_21986968	0.081	NM_152612	CCDC116	coiled-coil domain containing 116
chr17_-_39728304	0.080	NM_000226	KRT9	keratin 9
chr4_+_15779887	0.080	NM_001775	CD38	CD38 molecule
chr15_+_77287738	0.080		PSTPIP1	proline-serine-threonine phosphatase interacting protein 1
chr2_+_183608329	0.079		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr1_-_161168816	0.079	NM_005099	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr7_-_107880492	0.079	NM_001037132	NRCAM	neuronal cell adhesion molecule
chr17_-_10421858	0.079	NM_005963	MYH1	myosin, heavy chain 1, skeletal muscle, adult
chr20_+_30028410	0.078	NM_153324	DEFB123	defensin, beta 123
chr17_+_39382878	0.078	NM_031961	KRTAP9-2	keratin associated protein 9-2
chrX_-_135338640	0.078	NM_001173516	MAP7D3	MAP7 domain containing 3
chr1_+_116925991	0.077	NM_001160234	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_-_173886464	0.077	NM_000488	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr17_+_41052813	0.077	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr6_-_111888520	0.077	NM_001164283	TRAF3IP2	TRAF3 interacting protein 2
chr8_+_120079423	0.076	NM_006438	COLEC10	collectin sub-family member 10 (C-type lectin)
chr11_-_118972529	0.076		DPAGT1	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr19_-_36304200	0.075	NM_021232	PRODH2	proline dehydrogenase (oxidase) 2
chr11_-_85338313	0.074	NM_001142699	DLG2	discs, large homolog 2 (Drosophila)
chr1_+_67632168	0.073	NM_144701	IL23R	interleukin 23 receptor
chr1_+_15990300	0.073
chr6_-_33754712	0.072	NM_001143944	LEMD2	LEM domain containing 2
chr22_-_32853372	0.072	NM_174932	BPIFC	BPI fold containing family C
chr9_-_117692874	0.072	NM_001244 NM_001252290	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8
chr19_-_47291594	0.071	NM_005628	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5
chr13_+_32313678	0.070	NM_001166058 NM_130806	RXFP2	relaxin/insulin-like family peptide receptor 2
chr16_+_66995099	0.070	NM_001185177 NM_024922	CES3	carboxylesterase 3
chr2_+_103035148	0.068	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr6_-_32557431	0.068	NM_001243965 NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr1_-_247921707	0.068	NM_012353	OR1C1	olfactory receptor, family 1, subfamily C, member 1
chr1_-_109935869	0.067	NM_001205228	SORT1	sortilin 1
chr5_+_40841296	0.066	NM_032587	CARD6	caspase recruitment domain family, member 6
chr1_-_160549226	0.066		CD84	CD84 molecule
chr12_-_57410275	0.066	NM_001178054 NM_013251	TAC3	tachykinin 3
chr21_-_39956823	0.065	NM_001243429	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr12_-_56359794	0.065	NM_001200053 NM_001200054	PMEL	premelanosome protein
chr10_+_49893514	0.065	NM_020945	WDFY4	WDFY family member 4
chr15_-_43513196	0.064		EPB42	erythrocyte membrane protein band 4.2
chrX_-_100641143	0.063	NM_000061	BTK	Bruton agammaglobulinemia tyrosine kinase
chr7_+_141478241	0.063	NM_016944	TAS2R4	taste receptor, type 2, member 4
chr1_+_161692448	0.062	NM_001002901	FCRLB	Fc receptor-like B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.41	3.12e-04	GO:0006952	defense response
2.04	1.13e-03	GO:0002376	immune system process
1.34	2.94e-03	GO:0050896	response to stimulus
2.29	5.96e-03	GO:0006955	immune response
2.73	7.85e-03	GO:0002684	positive regulation of immune system process
3.80	1.40e-02	GO:0002696	positive regulation of leukocyte activation
3.13	1.65e-02	GO:0050778	positive regulation of immune response
3.74	1.72e-02	GO:0050867	positive regulation of cell activation
3.81	2.72e-02	GO:0051251	positive regulation of lymphocyte activation
6.48	3.93e-02	GO:0016064	immunoglobulin mediated immune response
2.82	4.32e-02	GO:0051240	positive regulation of multicellular organismal process
6.37	4.50e-02	GO:0019724	B cell mediated immunity
5.50	4.87e-02	GO:0050671	positive regulation of lymphocyte proliferation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.78	6.80e-05	GO:0005576	extracellular region
1.45	3.42e-04	GO:0071944	cell periphery
1.45	4.71e-04	GO:0005886	plasma membrane
4.30	1.01e-02	GO:0005765	lysosomal membrane
2.89	2.96e-02	GO:0010008	endosome membrane
1.98	3.06e-02	GO:0005615	extracellular space
2.87	3.25e-02	GO:0044440	endosomal part
1.28	4.02e-02	GO:0031224	intrinsic to membrane
3.43	4.16e-02	GO:0044437	vacuolar part
12.73	4.19e-02	GO:0042613	MHC class II protein complex
1.25	4.94e-02	GO:0044425	membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.64	3.28e-02	GO:0004872	receptor activity