Motif ID: GATA1..3.p2

Z-value: 2.717


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA3chr10_+_80967720.893.0e-03Click!
GATA2chr3_-_128212027-0.743.6e-02Click!
GATA1chrX_+_48644961-0.611.1e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_156820161 4.890 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_189839078 4.887 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_189839132 4.426 COL3A1
collagen, type III, alpha 1
chr2_+_189839113 4.155 COL3A1
collagen, type III, alpha 1
chr12_+_1738411 3.883 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr11_-_35547144 3.598 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr17_-_48278874 3.454 COL1A1
collagen, type I, alpha 1
chr2_-_190044330 3.423 NM_000393
COL5A2
collagen, type V, alpha 2
chr8_-_108510094 3.378 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chrX_+_57618268 3.289 NM_007157
ZXDB
zinc finger, X-linked, duplicated B
chr4_-_138453628 3.105 NM_019035
PCDH18
protocadherin 18
chr12_+_56075418 3.087 METTL7B
methyltransferase like 7B
chr1_-_72748147 2.953 NM_173808
NEGR1
neuronal growth regulator 1
chr8_-_93107442 2.930 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr1_+_164528914 2.840 PBX1
pre-B-cell leukemia homeobox 1
chr8_-_93107643 2.753 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_102104941 2.507 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_-_72748491 2.441


chr8_-_93029864 2.175 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_-_48099178 2.171 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr4_-_159092509 2.141 FAM198B
family with sequence similarity 198, member B
chr4_-_138453564 2.121 PCDH18
protocadherin 18
chr1_+_114522029 2.120 NM_020190
OLFML3
olfactomedin-like 3
chrX_-_57936853 2.103 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr3_-_112358758 2.039 CCDC80
coiled-coil domain containing 80
chr20_+_33299315 1.991 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr1_+_155829259 1.872 NM_152280
SYT11
synaptotagmin XI
chr17_-_48264039 1.869 COL1A1
collagen, type I, alpha 1
chr14_-_61115906 1.864 NM_005982
SIX1
SIX homeobox 1
chr11_-_96076328 1.835 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr3_-_114343791 1.813 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr20_+_12989616 1.797 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chrX_+_57618440 1.789 ZXDB
zinc finger, X-linked, duplicated B
chr1_-_86043932 1.775 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_-_38303307 1.745 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chrX_+_86772714 1.729 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr14_-_92413738 1.697 FBLN5
fibulin 5
chr1_+_155853546 1.659 SYT11
synaptotagmin XI
chr3_-_114343052 1.651 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr17_+_38599651 1.625 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr8_+_37654757 1.623 GPR124
G protein-coupled receptor 124
chr3_-_195310985 1.621 NM_001647
APOD
apolipoprotein D
chr15_-_93616358 1.613 NM_001166286
RGMA
RGM domain family, member A
chr5_+_119799898 1.601 PRR16
proline rich 16
chr2_-_38303265 1.589 CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr3_-_48700317 1.589 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr15_-_93616308 1.583 RGMA
RGM domain family, member A
chr8_-_93107881 1.575 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr10_+_70847817 1.571 NM_002727
SRGN
serglycin
chr14_-_60097223 1.565 RTN1
reticulon 1
chr6_+_72596699 1.559 RIMS1
regulating synaptic membrane exocytosis 1
chr12_+_56075329 1.528 NM_152637
METTL7B
methyltransferase like 7B
chr15_-_48937795 1.479 NM_000138
FBN1
fibrillin 1
chr11_-_9225780 1.476 DENND5A
DENN/MADD domain containing 5A
chr21_+_47545896 1.443 COL6A2
collagen, type VI, alpha 2
chr14_+_21538339 1.435 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chrX_+_66766350 1.433 AR
androgen receptor
chr5_-_139944045 1.433 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr10_+_70847857 1.416 SRGN
serglycin
chr5_-_19988293 1.411 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr4_+_134073180 1.409 PCDH10
protocadherin 10
chr13_-_33780142 1.397 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr11_-_27742224 1.385 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr5_+_82767492 1.374 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr5_+_119800004 1.371 NM_016644
PRR16
proline rich 16
chr3_-_49170490 1.358 NM_002292
LAMB2
laminin, beta 2 (laminin S)
chr3_-_112358510 1.348 CCDC80
coiled-coil domain containing 80
chr11_-_111782447 1.348 NM_001885
CRYAB
crystallin, alpha B
chr21_+_27012067 1.345 JAM2
junctional adhesion molecule 2
chr12_+_94542239 1.335 NM_005761
PLXNC1
plexin C1
chr5_+_139060295 1.332 CXXC5
CXXC finger protein 5
chr2_+_74685526 1.330 NM_012477
WBP1
WW domain binding protein 1
chr3_-_195310770 1.329 APOD
apolipoprotein D
chr2_-_214016332 1.329 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_-_158526698 1.327 NM_024007
EBF1
early B-cell factor 1
chr4_-_89618928 1.326 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr3_-_49170427 1.307 LAMB2
laminin, beta 2 (laminin S)
chr13_+_93879011 1.305 NM_005708
GPC6
glypican 6
chr9_+_18474078 1.303 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr12_-_91573264 1.300 NM_133503
DCN
decorin
chr10_-_92681025 1.297 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr12_-_91572328 1.291 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chrX_+_149531439 1.276 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr10_-_79397204 1.269 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_-_175869910 1.269 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr3_-_49851356 1.260 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr3_-_49851217 1.255 UBA7
ubiquitin-like modifier activating enzyme 7
chr15_-_93616891 1.247 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr16_+_67311412 1.246 NM_015432
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr11_-_65816650 1.240 NM_033036
GAL3ST3
galactose-3-O-sulfotransferase 3
chr9_-_16727887 1.231 BNC2
basonuclin 2
chr14_-_60097314 1.225 RTN1
reticulon 1
chr8_+_37654406 1.214 GPR124
G protein-coupled receptor 124
chr5_-_172755418 1.207 STC2
stanniocalcin 2
chr8_+_70405080 1.202 SULF1
sulfatase 1
chr1_-_182354649 1.201 GLUL
glutamate-ammonia ligase
chr8_+_62200524 1.195 NM_173519
CLVS1
clavesin 1
chr2_+_56411123 1.194 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr10_-_79397394 1.192 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr8_-_93075190 1.186 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_37654395 1.181 NM_032777
GPR124
G protein-coupled receptor 124
chr2_+_201473942 1.174 AOX1
aldehyde oxidase 1
chr11_-_102826433 1.157 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr19_-_50316360 1.145 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr3_-_9994057 1.133 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr15_-_90347534 1.133 ANPEP
alanyl (membrane) aminopeptidase
chr10_-_79397290 1.119 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr14_+_21467413 1.112 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr4_+_126237566 1.110 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr8_+_17434700 1.109 PDGFRL
platelet-derived growth factor receptor-like
chr10_-_79397470 1.108 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr8_+_70378858 1.108 NM_001128204
NM_015170
SULF1

sulfatase 1

chr2_-_145277879 1.106 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr6_+_72926144 1.104 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr11_+_113930296 1.092 ZBTB16
zinc finger and BTB domain containing 16
chr2_+_8822112 1.085 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_27998700 1.074 IFI6
interferon, alpha-inducible protein 6
chr7_+_100199881 1.060 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr11_-_2019007 1.056 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr19_+_46367517 1.055 NM_004497
FOXA3
forkhead box A3
chr12_+_79258794 1.055 SYT1
synaptotagmin I
chr15_-_93617091 1.054 NM_001166283
RGMA
RGM domain family, member A
chr13_-_33859835 1.049 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_+_43809805 1.043 NM_002373
MAP1A
microtubule-associated protein 1A
chr8_+_37654833 1.040 GPR124
G protein-coupled receptor 124
chr10_-_104473957 1.037 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr2_+_210444364 1.033 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr9_+_131191206 1.009 CERCAM
cerebral endothelial cell adhesion molecule
chr4_+_55095263 1.009 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr12_+_79258588 1.007 SYT1
synaptotagmin I
chr9_+_124086842 1.005 GSN
gelsolin
chr4_-_186877869 1.002 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr10_-_81205091 0.997 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr1_+_51435641 0.996 NM_078626
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr6_+_27777713 0.994 NM_003536
HIST1H3H
histone cluster 1, H3h
chr15_-_90347173 0.984 ANPEP
alanyl (membrane) aminopeptidase
chr3_-_197676755 0.971 NM_001134435
IQCG
IQ motif containing G
chr3_-_51993955 0.960 PCBP4
poly(rC) binding protein 4
chr17_-_48278987 0.933 NM_000088
COL1A1
collagen, type I, alpha 1
chr19_-_1401474 0.928 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr17_-_5404304 0.928 NM_001162371
LOC728392
uncharacterized LOC728392
chr4_+_8951476 0.919 NM_001040071
LOC650293
seven transmembrane helix receptor
chr3_-_114478117 0.907 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr11_-_1769086 0.907 IFITM10
interferon induced transmembrane protein 10
chr2_+_210444154 0.904 MAP2
microtubule-associated protein 2
chr3_+_45067750 0.901 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr10_-_92680784 0.900 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr19_-_50143350 0.894 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr9_+_35829208 0.893 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr20_+_37353126 0.887 SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr8_-_93111915 0.886 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_67584251 0.885 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_27998658 0.883 IFI6
interferon, alpha-inducible protein 6
chr12_+_21679190 0.882 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr9_+_35829375 0.875 NM_001042590
TMEM8B
transmembrane protein 8B
chr18_-_34409084 0.868 NM_015476
TPGS2
tubulin polyglutamylase complex subunit 2
chr2_-_145277568 0.864 ZEB2
zinc finger E-box binding homeobox 2
chr11_+_62380212 0.859 NM_000327
ROM1
retinal outer segment membrane protein 1
chrX_-_71792897 0.858 NM_001166418
NM_001166419
NM_001166420
NM_001166422
NM_001166448
NM_018486
HDAC8





histone deacetylase 8





chr10_+_69869249 0.857 NM_032578
MYPN
myopalladin
chr1_+_51435911 0.855 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr2_+_27301693 0.853 EMILIN1
elastin microfibril interfacer 1
chr6_+_72596648 0.850 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_168271852 0.849


chr10_-_79397546 0.848 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr4_-_186733372 0.841 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr12_+_79258517 0.839 SYT1
synaptotagmin I
chr12_+_79258448 0.837 NM_005639
SYT1
synaptotagmin I
chr17_-_62050200 0.829 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr2_-_127864505 0.825 NM_004305
NM_139343
NM_139344
NM_139345
NM_139346
NM_139347
NM_139348
NM_139349
NM_139350
NM_139351
BIN1









bridging integrator 1









chr4_+_129730772 0.823 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr1_-_154943001 0.822 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr18_+_72998258 0.821 TSHZ1
teashirt zinc finger homeobox 1
chr3_-_121379701 0.821 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_+_142838596 0.818 NM_004267
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr18_-_34408845 0.816 TPGS2
tubulin polyglutamylase complex subunit 2
chr20_+_37353104 0.815 NM_080552
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr3_-_9920633 0.811 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr17_-_48262900 0.809 COL1A1
collagen, type I, alpha 1
chr19_+_49977817 0.806 NM_001204503
FLT3LG
fms-related tyrosine kinase 3 ligand
chr16_+_69680959 0.800 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_-_214015053 0.799 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr7_+_90338711 0.794 NM_012395
CDK14
cyclin-dependent kinase 14
chr9_+_135037333 0.791 NM_032536
NTNG2
netrin G2
chr15_+_91769329 0.785 SV2B
synaptic vesicle glycoprotein 2B
chr18_-_34408948 0.785 TPGS2
tubulin polyglutamylase complex subunit 2
chr9_-_95244750 0.784 NM_001193335
NM_017680
ASPN

asporin

chr4_-_186732047 0.784 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr1_+_226016428 0.781 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr5_-_139943829 0.780 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr14_-_75593623 0.771 NEK9
NIMA (never in mitosis gene a)- related kinase 9
chr14_-_60097531 0.766 NM_206852
RTN1
reticulon 1
chr6_+_132891460 0.763 NM_175067
TAAR6
trace amine associated receptor 6
chrX_+_100333835 0.759 NM_021637
TMEM35
transmembrane protein 35
chr11_+_113930430 0.754 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr11_-_2019070 0.748 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr11_-_2016743 0.747 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr8_+_70405027 0.743 NM_001128205
NM_001128206
SULF1

sulfatase 1

chrX_+_102883647 0.734 NM_001006640
TCEAL1
transcription elongation factor A (SII)-like 1
chr13_-_38172862 0.734 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor




Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 5.35e-09 GO:0009987 cellular process
2.46 3.12e-08 GO:0006414 translational elongation
2.53 7.95e-08 GO:0006415 translational termination
1.43 8.19e-08 GO:0032774 RNA biosynthetic process
2.44 1.16e-07 GO:0043241 protein complex disassembly
2.44 1.16e-07 GO:0043624 cellular protein complex disassembly
2.34 1.60e-07 GO:0032984 macromolecular complex disassembly
2.34 1.60e-07 GO:0034623 cellular macromolecular complex disassembly
2.51 3.04e-07 GO:0019080 viral genome expression
2.51 3.04e-07 GO:0019083 viral transcription
1.98 1.62e-06 GO:0035270 endocrine system development
2.20 2.22e-06 GO:0031018 endocrine pancreas development
2.08 2.85e-06 GO:0031016 pancreas development
1.12 3.15e-06 GO:0050794 regulation of cellular process
1.93 3.58e-06 GO:0022411 cellular component disassembly
1.93 3.58e-06 GO:0071845 cellular component disassembly at cellular level
1.10 4.95e-06 GO:0065007 biological regulation
1.11 1.07e-05 GO:0050789 regulation of biological process
1.17 1.52e-05 GO:0032502 developmental process
1.21 2.22e-05 GO:0071842 cellular component organization at cellular level
1.18 3.49e-05 GO:0016043 cellular component organization
1.53 4.16e-05 GO:0034621 cellular macromolecular complex subunit organization
1.17 5.92e-05 GO:0007275 multicellular organismal development
1.53 6.14e-05 GO:0006325 chromatin organization
1.18 8.75e-05 GO:0048856 anatomical structure development
1.21 1.48e-04 GO:0048522 positive regulation of cellular process
1.28 1.99e-04 GO:0007399 nervous system development
1.19 2.23e-04 GO:0048731 system development
1.19 2.47e-04 GO:0048518 positive regulation of biological process
1.37 4.82e-04 GO:0043933 macromolecular complex subunit organization
1.20 5.04e-04 GO:0048519 negative regulation of biological process
1.21 5.63e-04 GO:0048523 negative regulation of cellular process
1.19 7.20e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 7.46e-04 GO:0071840 cellular component organization or biogenesis
1.34 7.58e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.23 9.20e-04 GO:0010467 gene expression
1.84 1.13e-03 GO:0022415 viral reproductive process
1.90 1.60e-03 GO:0019058 viral infectious cycle
1.33 2.43e-03 GO:0031324 negative regulation of cellular metabolic process
1.31 3.02e-03 GO:0009892 negative regulation of metabolic process
1.23 3.04e-03 GO:0016070 RNA metabolic process
1.15 3.59e-03 GO:0080090 regulation of primary metabolic process
1.85 3.73e-03 GO:0006333 chromatin assembly or disassembly
1.33 4.61e-03 GO:0006351 transcription, DNA-dependent
1.12 6.10e-03 GO:0044260 cellular macromolecule metabolic process
1.41 6.38e-03 GO:0051253 negative regulation of RNA metabolic process
1.14 7.14e-03 GO:0031323 regulation of cellular metabolic process
1.43 1.00e-02 GO:0019226 transmission of nerve impulse
1.43 1.00e-02 GO:0035637 multicellular organismal signaling
1.46 1.19e-02 GO:0016032 viral reproduction
1.30 1.32e-02 GO:0022008 neurogenesis
1.37 1.50e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 2.11e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.34 2.18e-02 GO:0009890 negative regulation of biosynthetic process
1.18 2.27e-02 GO:0090304 nucleic acid metabolic process
1.16 2.30e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 2.72e-02 GO:0043170 macromolecule metabolic process
1.37 2.85e-02 GO:0048666 neuron development
1.34 3.00e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.36 3.32e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 3.32e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.43 3.34e-02 GO:0007268 synaptic transmission
1.30 3.41e-02 GO:0048699 generation of neurons
1.36 3.65e-02 GO:0071822 protein complex subunit organization
1.34 4.15e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.50 4.81e-02 GO:0006412 translation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 7.16e-15 GO:0044424 intracellular part
1.09 7.39e-15 GO:0005622 intracellular
1.24 1.73e-12 GO:0032991 macromolecular complex
1.11 4.69e-10 GO:0005737 cytoplasm
1.16 4.85e-10 GO:0005634 nucleus
1.09 1.01e-09 GO:0043229 intracellular organelle
1.09 1.13e-09 GO:0043226 organelle
1.10 2.42e-08 GO:0043227 membrane-bounded organelle
1.10 3.16e-08 GO:0043231 intracellular membrane-bounded organelle
1.20 1.36e-06 GO:0043234 protein complex
1.12 6.32e-06 GO:0044422 organelle part
1.83 1.68e-05 GO:0005840 ribosome
1.12 2.64e-05 GO:0044446 intracellular organelle part
2.32 4.03e-05 GO:0022626 cytosolic ribosome
1.37 1.98e-04 GO:0044451 nucleoplasm part
1.80 6.23e-04 GO:0044445 cytosolic part
1.25 9.17e-04 GO:0005654 nucleoplasm
1.09 2.43e-03 GO:0044444 cytoplasmic part
1.45 3.39e-03 GO:0045202 synapse
1.18 7.65e-03 GO:0005829 cytosol
1.28 1.04e-02 GO:0042995 cell projection
1.35 3.28e-02 GO:0030529 ribonucleoprotein complex
1.16 3.34e-02 GO:0044428 nuclear part
2.45 3.81e-02 GO:0022627 cytosolic small ribosomal subunit
1.43 4.71e-02 GO:0044433 cytoplasmic vesicle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 6.84e-20 GO:0005515 protein binding
1.09 7.90e-16 GO:0005488 binding
2.05 6.49e-07 GO:0003735 structural constituent of ribosome
1.36 3.30e-06 GO:0030528 transcription regulator activity
1.46 8.49e-06 GO:0005198 structural molecule activity
1.89 1.52e-04 GO:0003714 transcription corepressor activity
1.35 2.12e-03 GO:0043565 sequence-specific DNA binding
1.48 2.73e-03 GO:0003712 transcription cofactor activity
1.47 3.16e-03 GO:0000988 protein binding transcription factor activity
1.47 3.16e-03 GO:0000989 transcription factor binding transcription factor activity
1.48 1.60e-02 GO:0016564 transcription repressor activity
1.49 1.90e-02 GO:0008134 transcription factor binding
1.25 4.41e-02 GO:0001071 nucleic acid binding transcription factor activity
1.25 4.41e-02 GO:0003700 sequence-specific DNA binding transcription factor activity