Motif ID: GFI1.p2

Z-value: 1.232


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1chr1_-_92951593-0.724.5e-02Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_167040700 1.392 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167040659 1.372 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_92414004 1.233 NM_006329
FBLN5
fibulin 5
chr6_-_167040506 1.147 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr10_-_93392744 0.953 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr10_-_93392857 0.944 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr14_-_61115906 0.931 NM_005982
SIX1
SIX homeobox 1
chr14_-_60097223 0.867 RTN1
reticulon 1
chr2_-_190044330 0.857 NM_000393
COL5A2
collagen, type V, alpha 2
chr5_-_172755418 0.849 STC2
stanniocalcin 2
chr14_-_60097314 0.847 RTN1
reticulon 1
chr5_-_172755195 0.813 STC2
stanniocalcin 2
chr17_-_1619473 0.785 MIR22HG
MIR22 host gene (non-protein coding)
chr5_-_19988293 0.777 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chrX_+_16964730 0.762 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr13_-_67804432 0.750 NM_020403
NM_203487
PCDH9

protocadherin 9

chr2_-_45236521 0.726 NM_016932
SIX2
SIX homeobox 2
chr11_-_96076328 0.715 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr1_-_92351476 0.713 TGFBR3
transforming growth factor, beta receptor III
chr3_+_45927995 0.709 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr14_+_104394751 0.686 NM_153046
TDRD9
tudor domain containing 9
chr17_+_19281726 0.642 NM_002749
NM_139034
MAPK7

mitogen-activated protein kinase 7

chr11_+_113930430 0.614 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr9_+_79093256 0.605 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_+_149571029 0.604 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr5_-_127873734 0.588 NM_001999
FBN2
fibrillin 2
chr17_+_19281013 0.584 NM_139032
NM_139033
MAPK7

mitogen-activated protein kinase 7

chr14_-_52535765 0.558 NID2
nidogen 2 (osteonidogen)
chr5_-_149535138 0.553 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr5_-_149535420 0.548 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_-_46598250 0.548 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr8_+_17354562 0.526 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr7_+_29603388 0.525 NM_175887
PRR15
proline rich 15
chr14_-_52535711 0.523 NID2
nidogen 2 (osteonidogen)
chr7_+_29603499 0.522 PRR15
proline rich 15
chr12_+_51818669 0.521 SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr14_-_52535945 0.518 NM_007361
NID2
nidogen 2 (osteonidogen)
chrX_-_101771641 0.518 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr3_+_111393522 0.511 NM_001185106
NM_153268
PLCXD2

phosphatidylinositol-specific phospholipase C, X domain containing 2

chr5_-_149535309 0.510 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_+_145438437 0.490 NM_006472
TXNIP
thioredoxin interacting protein
chr1_-_92351613 0.488 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr14_-_58764805 0.486 FLJ31306
uncharacterized LOC379025
chr17_+_61699786 0.481 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr1_+_112938857 0.481 LOC100129406
CTTNBP2NL
uncharacterized LOC100129406
CTTNBP2 N-terminal like
chr17_-_48278987 0.480 NM_000088
COL1A1
collagen, type I, alpha 1
chr11_-_119293848 0.471 THY1
Thy-1 cell surface antigen
chr1_+_164528586 0.466 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr5_+_140529619 0.464 NM_018939
PCDHB6
protocadherin beta 6
chr14_-_52535737 0.463 NID2
nidogen 2 (osteonidogen)
chr5_-_150138081 0.458 NM_001135644
DCTN4
dynactin 4 (p62)
chr12_+_51818592 0.458 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr5_-_137090049 0.456


chr14_-_53417808 0.453 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr2_+_172950207 0.446 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr14_-_73360792 0.443 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr17_-_48278874 0.442 COL1A1
collagen, type I, alpha 1
chr10_+_76586299 0.440 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr7_-_137531585 0.439 NM_004717
DGKI
diacylglycerol kinase, iota
chr5_+_95066628 0.435 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr6_-_46459010 0.435 NM_001251974
RCAN2
regulator of calcineurin 2
chr19_+_925984 0.430 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr16_+_12995454 0.426 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr9_-_79520878 0.423 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr11_-_119294242 0.423 NM_006288
THY1
Thy-1 cell surface antigen
chr6_+_33359624 0.421 KIFC1
kinesin family member C1
chr20_+_33292117 0.419 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr14_+_101292483 0.416


chr6_+_33359620 0.416 KIFC1
kinesin family member C1
chr6_+_33359604 0.414 KIFC1
kinesin family member C1
chr17_+_19282058 0.410 MAPK7
mitogen-activated protein kinase 7
chr14_+_53019865 0.406 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr11_-_128391888 0.401 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr12_+_90103470 0.395 LOC338758
uncharacterized LOC338758
chr19_-_45926819 0.389 NM_202001
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr15_-_48937068 0.387 FBN1
fibrillin 1
chr2_-_73460326 0.387 NM_032319
PRADC1
protease-associated domain containing 1
chr4_-_138453628 0.386 NM_019035
PCDH18
protocadherin 18
chr3_+_172468469 0.385 ECT2
epithelial cell transforming sequence 2 oncogene
chr5_-_137090033 0.381 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr5_-_121413967 0.380 LOX
lysyl oxidase
chr5_-_124080773 0.374 NM_020747
ZNF608
zinc finger protein 608
chr14_-_53019036 0.368 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr14_-_74551073 0.366 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_+_162602198 0.356 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr20_-_44485953 0.356 NM_005469
ACOT8
acyl-CoA thioesterase 8
chr1_+_162602308 0.351 DDR2
discoidin domain receptor tyrosine kinase 2
chr16_-_4896197 0.350 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr4_-_76598558 0.349 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr14_-_74551159 0.348 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr2_+_33172368 0.348 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr4_+_1873149 0.345 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr10_+_102792166 0.342 SFXN3
sideroflexin 3
chr3_+_131100514 0.341 NM_001171905
NM_001171906
NM_152395
NUDT16


nudix (nucleoside diphosphate linked moiety X)-type motif 16


chr9_-_20622476 0.340 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_182360889 0.340 GLUL
glutamate-ammonia ligase
chr10_+_102792161 0.339 SFXN3
sideroflexin 3
chr1_+_159750756 0.335 NM_017823
DUSP23
dual specificity phosphatase 23
chr5_-_121413906 0.334 LOX
lysyl oxidase
chr5_+_140729723 0.333 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr19_-_45926631 0.331 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr5_+_130506656 0.331 LYRM7
Lyrm7 homolog (mouse)
chr17_-_19281494 0.331 NM_001243475
B9D1
B9 protein domain 1
chr2_+_20646831 0.330 NM_004040
RHOB
ras homolog gene family, member B
chrX_-_15872921 0.324 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_+_163038564 0.321 NM_005613
RGS4
regulator of G-protein signaling 4
chrX_-_62975005 0.319 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr1_+_145477018 0.318 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr1_+_164528914 0.311 PBX1
pre-B-cell leukemia homeobox 1
chr12_+_55248298 0.309 NM_058173
MUCL1
mucin-like 1
chr1_+_213123853 0.307 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr3_+_20081523 0.306 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr12_-_120315074 0.306 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr17_-_45973142 0.302


chr4_-_76598563 0.301 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr11_+_19372270 0.301 NM_001111018
NAV2
neuron navigator 2
chr19_+_36606337 0.300 TBCB
tubulin folding cofactor B
chr10_-_46168156 0.299 NM_001128324
NM_174890
ZFAND4

zinc finger, AN1-type domain 4

chr2_+_170662044 0.298 SSB
Sjogren syndrome antigen B (autoantigen La)
chr14_+_58765209 0.298 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr17_-_29648631 0.297 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr1_-_24194760 0.296 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr4_-_57522469 0.295 NM_001145459
NM_139211
HOPX

HOP homeobox

chr5_-_137089990 0.294 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr11_+_64879294 0.293 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chr20_-_32307889 0.293 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chr11_-_67275549 0.292 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr17_+_61699715 0.292 MAP3K3
mitogen-activated protein kinase kinase kinase 3
chrX_-_15872905 0.292


chr3_+_50273745 0.289 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chrX_-_62974987 0.289 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr20_-_58508668 0.287 SYCP2
synaptonemal complex protein 2
chr15_+_99645152 0.287 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr17_-_55980749 0.286 NM_017949
CUEDC1
CUE domain containing 1
chr5_-_160112266 0.286 ATP10B
ATPase, class V, type 10B
chr5_+_141348646 0.285 RNF14
ring finger protein 14
chr1_-_182360400 0.284 NM_001033056
GLUL
glutamate-ammonia ligase
chr14_+_29236171 0.283 NM_005249
FOXG1
forkhead box G1
chr7_+_134331530 0.281 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr19_-_22034769 0.280 ZNF43
zinc finger protein 43
chr15_+_91498056 0.280 NM_001017919
NM_033544
RCCD1

RCC1 domain containing 1

chr2_+_23608297 0.280 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chrX_+_66788682 0.277 NM_001011645
AR
androgen receptor
chr21_-_47648685 0.274 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr7_-_121784236 0.272 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr3_+_50273645 0.272 NM_002070
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr4_+_165878129 0.271 C4orf39
chromosome 4 open reading frame 39
chr3_+_183165402 0.271 LOC100505687
uncharacterized LOC100505687
chr5_+_151151483 0.269 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr20_-_57425957 0.268 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr19_-_45926759 0.268 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_55972997 0.265 ISOC2
isochorismatase domain containing 2
chr11_+_58874614 0.264 NM_001142703
NM_001142704
NM_198947
FAM111B


family with sequence similarity 111, member B


chr16_+_31484497 0.262 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr9_-_73029539 0.262 NM_001206
KLF9
Kruppel-like factor 9
chr17_+_1665306 0.262 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr5_-_146833150 0.261 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr7_-_27196163 0.260 NM_006896
HOXA7
homeobox A7
chr7_+_99102865 0.260 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr16_+_53133063 0.259 CHD9
chromodomain helicase DNA binding protein 9
chr11_-_40315663 0.258 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr5_-_59783885 0.258 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_111312522 0.254 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr12_-_56106061 0.253 NM_001144997
ITGA7
integrin, alpha 7
chrX_-_62974942 0.251 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr4_+_165878098 0.251 NM_153027
C4orf39
chromosome 4 open reading frame 39
chr20_-_30311693 0.248 BCL2L1
BCL2-like 1
chr4_+_4861371 0.248 NM_002448
MSX1
msh homeobox 1
chr3_+_50273575 0.246 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr22_-_28197469 0.246 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr17_-_5095131 0.245 NM_032530
ZNF594
zinc finger protein 594
chr1_+_62902325 0.245 NM_003368
USP1
ubiquitin specific peptidase 1
chr3_+_50273635 0.244 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr11_-_68609322 0.243 CPT1A
carnitine palmitoyltransferase 1A (liver)
chr10_+_31610063 0.242 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr17_+_1619816 0.241 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr19_-_14247400 0.240 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr19_+_1269244 0.240 NM_001280
CIRBP
cold inducible RNA binding protein
chr3_+_184055275 0.240 NM_144635
FAM131A
family with sequence similarity 131, member A
chr19_-_14247267 0.240 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chrX_-_15872938 0.239 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_109969058 0.238 NM_001199772
NM_002790
NM_001199773
NM_001199774
PSMA5



proteasome (prosome, macropain) subunit, alpha type, 5



chr2_-_239148626 0.238 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr1_-_27998700 0.236 IFI6
interferon, alpha-inducible protein 6
chr3_+_8543508 0.234 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr5_+_140762401 0.234 NM_018920
NM_032087
PCDHGA7

protocadherin gamma subfamily A, 7

chr17_+_58755158 0.234 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr9_-_91793375 0.233 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr3_-_172428773 0.232 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr19_-_12595625 0.232 NM_152601
ZNF709
zinc finger protein 709
chr16_-_1876528 0.231 HAGH
hydroxyacylglutathione hydrolase
chr17_+_1665342 0.229 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_+_50775960 0.229 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr19_-_55972935 0.228 ISOC2
isochorismatase domain containing 2
chr17_+_1665281 0.227 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_38574042 0.227 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr1_-_27998719 0.227 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr7_+_7222142 0.225 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chrX_-_15872882 0.225 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr6_-_46459710 0.225 NM_001251973
RCAN2
regulator of calcineurin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.86 1.87e-14 GO:0007049 cell cycle
1.92 2.18e-10 GO:0022403 cell cycle phase
1.83 3.58e-10 GO:0022402 cell cycle process
1.39 1.07e-08 GO:0071842 cellular component organization at cellular level
2.07 1.92e-08 GO:0000279 M phase
1.88 9.34e-08 GO:0000278 mitotic cell cycle
1.36 1.43e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.48 2.27e-07 GO:0006996 organelle organization
1.30 5.08e-07 GO:0016043 cellular component organization
1.30 7.57e-07 GO:0060255 regulation of macromolecule metabolic process
1.10 1.75e-06 GO:0009987 cellular process
1.29 2.36e-06 GO:0071840 cellular component organization or biogenesis
1.17 3.43e-06 GO:0050794 regulation of cellular process
1.78 3.52e-06 GO:0051276 chromosome organization
2.14 4.34e-06 GO:0000087 M phase of mitotic cell cycle
1.34 1.30e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.15 2.15e-05 GO:0065007 biological regulation
1.33 3.15e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.26 3.65e-05 GO:0080090 regulation of primary metabolic process
1.34 3.97e-05 GO:0051252 regulation of RNA metabolic process
1.15 4.49e-05 GO:0050789 regulation of biological process
1.35 4.83e-05 GO:0006355 regulation of transcription, DNA-dependent
2.07 5.31e-05 GO:0000280 nuclear division
2.07 5.31e-05 GO:0007067 mitosis
2.03 7.90e-05 GO:0048285 organelle fission
1.24 8.22e-05 GO:0019222 regulation of metabolic process
1.46 1.57e-04 GO:0051641 cellular localization
1.30 1.61e-04 GO:0010468 regulation of gene expression
1.24 2.95e-04 GO:0031323 regulation of cellular metabolic process
1.28 5.69e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86 9.49e-04 GO:0051301 cell division
1.72 1.00e-03 GO:0034621 cellular macromolecular complex subunit organization
1.57 1.01e-03 GO:0071844 cellular component assembly at cellular level
1.74 1.06e-03 GO:0006325 chromatin organization
1.27 1.09e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.84 1.40e-03 GO:0034622 cellular macromolecular complex assembly
1.91 1.70e-03 GO:0051325 interphase
1.24 1.84e-03 GO:0034641 cellular nitrogen compound metabolic process
2.57 2.18e-03 GO:0065004 protein-DNA complex assembly
2.52 2.44e-03 GO:0071824 protein-DNA complex subunit organization
1.63 2.49e-03 GO:0006259 DNA metabolic process
1.26 3.41e-03 GO:0009889 regulation of biosynthetic process
1.88 4.53e-03 GO:0051329 interphase of mitotic cell cycle
1.43 5.85e-03 GO:0051649 establishment of localization in cell
1.26 5.98e-03 GO:0031326 regulation of cellular biosynthetic process
1.22 7.49e-03 GO:0006807 nitrogen compound metabolic process
1.25 1.02e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.01 1.07e-02 GO:0000075 cell cycle checkpoint
1.77 1.20e-02 GO:0010564 regulation of cell cycle process
1.28 1.21e-02 GO:0090304 nucleic acid metabolic process
1.28 1.26e-02 GO:0048523 negative regulation of cellular process
1.97 1.34e-02 GO:0071156 regulation of cell cycle arrest
1.62 1.43e-02 GO:0006974 response to DNA damage stimulus
1.56 1.71e-02 GO:0051726 regulation of cell cycle
1.18 2.04e-02 GO:0044260 cellular macromolecule metabolic process
2.22 2.18e-02 GO:0006333 chromatin assembly or disassembly
1.13 2.47e-02 GO:0044237 cellular metabolic process
1.26 3.02e-02 GO:0048519 negative regulation of biological process
1.45 4.41e-02 GO:0033554 cellular response to stress
2.55 4.91e-02 GO:0045637 regulation of myeloid cell differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.36 1.17e-23 GO:0005634 nucleus
1.16 2.06e-21 GO:0044424 intracellular part
1.15 3.23e-21 GO:0005622 intracellular
1.20 9.74e-21 GO:0043229 intracellular organelle
1.19 1.39e-20 GO:0043226 organelle
1.21 1.97e-18 GO:0043227 membrane-bounded organelle
1.21 1.99e-18 GO:0043231 intracellular membrane-bounded organelle
1.98 1.92e-10 GO:0005694 chromosome
2.01 4.50e-09 GO:0044427 chromosomal part
1.34 1.25e-07 GO:0043228 non-membrane-bounded organelle
1.34 1.25e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.39 1.96e-07 GO:0005829 cytosol
1.38 2.34e-07 GO:0044428 nuclear part
1.20 5.17e-07 GO:0044422 organelle part
1.20 5.78e-07 GO:0044446 intracellular organelle part
1.41 1.00e-06 GO:0031981 nuclear lumen
1.14 1.57e-06 GO:0005737 cytoplasm
1.47 2.77e-06 GO:0005654 nucleoplasm
1.32 1.23e-05 GO:0031974 membrane-enclosed lumen
2.14 2.24e-05 GO:0000785 chromatin
1.32 3.15e-05 GO:0070013 intracellular organelle lumen
1.32 3.41e-05 GO:0043233 organelle lumen
1.23 8.54e-05 GO:0032991 macromolecular complex
2.25 1.59e-04 GO:0044454 nuclear chromosome part
1.59 2.20e-04 GO:0015630 microtubule cytoskeleton
3.03 5.32e-04 GO:0000922 spindle pole
2.04 7.10e-04 GO:0000228 nuclear chromosome
1.15 9.84e-04 GO:0044444 cytoplasmic part
1.24 1.07e-03 GO:0043234 protein complex
2.08 1.77e-03 GO:0005819 spindle
1.32 6.38e-03 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 2.45e-15 GO:0005488 binding
1.22 3.33e-13 GO:0005515 protein binding
1.34 4.96e-06 GO:0003677 DNA binding
1.25 6.39e-05 GO:0003676 nucleic acid binding
1.57 1.74e-04 GO:0019899 enzyme binding
1.98 6.43e-03 GO:0019901 protein kinase binding
1.18 6.57e-03 GO:0043169 cation binding
1.18 6.65e-03 GO:0043167 ion binding
1.18 6.95e-03 GO:0046872 metal ion binding
1.27 9.82e-03 GO:0008270 zinc ion binding
2.58 2.26e-02 GO:0042393 histone binding
1.80 3.68e-02 GO:0019900 kinase binding
1.62 3.84e-02 GO:0003712 transcription cofactor activity
1.62 4.18e-02 GO:0000988 protein binding transcription factor activity
1.62 4.18e-02 GO:0000989 transcription factor binding transcription factor activity