Motif ID: GFI1B.p2

Z-value: 1.010


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1Bchr9_+_1358540970.167.0e-01Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_28124915 4.169 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr17_-_56494930 3.023 NM_017763
RNF43
ring finger protein 43
chr1_+_101702304 1.765 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr2_-_113542970 1.743 NM_000575
IL1A
interleukin 1, alpha
chr17_-_56494889 1.738 RNF43
ring finger protein 43
chr15_+_40509628 1.700 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr5_+_140261792 1.585 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr1_+_101702561 1.428 S1PR1
sphingosine-1-phosphate receptor 1
chr8_+_124194873 1.354 FAM83A
family with sequence similarity 83, member A
chr2_-_165424993 1.316 GRB14
growth factor receptor-bound protein 14
chr11_+_18287807 1.305 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr12_-_8815479 1.204 MFAP5
microfibrillar associated protein 5
chr11_+_34654010 1.194 NM_001206616
EHF
ets homologous factor
chr5_+_66124603 1.073 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_-_133748828 1.003 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr6_+_90272036 0.985 NM_001242811
ANKRD6
ankyrin repeat domain 6
chr2_-_113594325 0.878 NM_000576
IL1B
interleukin 1, beta
chr8_+_124194751 0.797 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr18_+_29027731 0.797 NM_001944
DSG3
desmoglein 3
chr6_-_26216871 0.783 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr10_+_118187381 0.774 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr9_+_12693385 0.714 NM_000550
TYRP1
tyrosinase-related protein 1
chr3_+_142375738 0.651 NM_001172312
PLS1
plastin 1
chr14_+_96722546 0.643 NM_000710
BDKRB1
bradykinin receptor B1
chr14_+_21510384 0.620 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chrX_-_33146543 0.600 NM_004010
NM_004009
DMD

dystrophin

chr11_-_118135197 0.598 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr18_+_21452981 0.584 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr4_+_77610610 0.551 SHROOM3
shroom family member 3
chr1_-_242612757 0.548 NM_001195811
NM_001195812
PLD5

phospholipase D family, member 5

chr7_+_18548899 0.547 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr1_+_220960038 0.539 NM_022746
MARC1
mitochondrial amidoxime reducing component 1
chr1_+_220701800 0.534 MARK1
MAP/microtubule affinity-regulating kinase 1
chr5_+_68800003 0.518 NM_001205255
OCLN
occludin
chr3_-_33700932 0.513 NM_001207044
CLASP2
cytoplasmic linker associated protein 2
chr1_+_156254069 0.511 NM_032323
TMEM79
transmembrane protein 79
chr12_-_8815266 0.505 MFAP5
microfibrillar associated protein 5
chr4_-_76944585 0.500 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_-_134373618 0.492 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr6_+_12290528 0.486 NM_001168319
NM_001955
EDN1

endothelin 1

chr6_+_43738177 0.483 VEGFA
vascular endothelial growth factor A
chr12_-_71148063 0.460 PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_-_153085963 0.454 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chrX_+_17393806 0.453 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_+_207804277 0.416 NM_173077
CPO
carboxypeptidase O
chr2_+_163200582 0.407 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr6_+_43738394 0.401 VEGFA
vascular endothelial growth factor A
chr3_-_190040192 0.396 NM_021101
CLDN1
claudin 1
chr17_+_70117168 0.378 SOX9
SRY (sex determining region Y)-box 9
chr6_-_138820578 0.374 NM_001144060
NHSL1
NHS-like 1
chr11_+_112046207 0.372 NM_031938
BCO2
beta-carotene oxygenase 2
chrX_+_17393877 0.366 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr15_-_83953465 0.355 NM_001717
BNC1
basonuclin 1
chr11_-_118134986 0.340 MPZL2
myelin protein zero-like 2
chr7_-_16505292 0.337 NM_015464
SOSTDC1
sclerostin domain containing 1
chrX_+_17393349 0.318 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chrX_+_147800610 0.310 NM_001170628
AFF2
AF4/FMR2 family, member 2
chr3_-_151034514 0.307 NM_023915
GPR87
G protein-coupled receptor 87
chr17_+_70117177 0.306 SOX9
SRY (sex determining region Y)-box 9
chr1_+_26872306 0.304 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr8_+_32504250 0.295 NM_013959
NRG1
neuregulin 1
chr18_+_47088400 0.295 NM_006033
LIPG
lipase, endothelial
chr19_-_10628606 0.294 NM_001166215
S1PR5
sphingosine-1-phosphate receptor 5
chr7_-_112727832 0.290 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr8_+_32579350 0.284 NM_001159996
NRG1
neuregulin 1
chr21_-_27512668 0.278 NM_001136016
APP
amyloid beta (A4) precursor protein
chr12_-_18890917 0.274 NM_033123
PLCZ1
phospholipase C, zeta 1
chr8_+_6566153 0.273 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr22_+_29449877 0.270 ZNRF3
zinc and ring finger 3
chr12_-_8815370 0.267 NM_003480
MFAP5
microfibrillar associated protein 5
chr19_-_13227212 0.266 NM_001142554
NM_017722
NM_001136035
TRMT1


TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)


chr17_-_9694613 0.264 NM_001105571
NM_001220493
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr2_+_163200623 0.260 GCA
grancalcin, EF-hand calcium binding protein
chr1_-_116383323 0.259 NM_001111061
NHLH2
nescient helix loop helix 2
chr1_+_220701547 0.259 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr17_+_41052813 0.259 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr10_+_74653338 0.253 NM_152635
OIT3
oncoprotein induced transcript 3
chr17_-_37322413 0.250 NM_001143968
ARL5C
ADP-ribosylation factor-like 5C
chr11_+_20620945 0.249 NM_004211
SLC6A5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr12_-_123187842 0.246 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr8_-_57026540 0.243 NM_005372
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
chr1_-_116383692 0.242 NM_005599
NHLH2
nescient helix loop helix 2
chr3_-_123339178 0.241 MYLK
myosin light chain kinase
chr7_-_82073020 0.240 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_+_119813600 0.239


chr2_+_183582667 0.237 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr17_-_3499124 0.237 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr4_-_72649734 0.237 NM_000583
GC
group-specific component (vitamin D binding protein)
chrX_+_105937067 0.237 NM_024539
RNF128
ring finger protein 128
chr10_-_113933517 0.236 GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr1_+_26872342 0.235 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_+_113229548 0.232 NM_001143854
NM_014954
RPH3A

rabphilin 3A homolog (mouse)

chr22_-_28315202 0.232 PITPNB
phosphatidylinositol transfer protein, beta
chr12_+_85430098 0.229 NM_001079910
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr13_-_86373328 0.227 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr4_+_15471488 0.224 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr7_+_127233688 0.224 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr6_+_26087447 0.222 NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
HFE








hemochromatosis








chrX_+_49832214 0.217 NM_000084
CLCN5
chloride channel 5
chr1_+_27189628 0.217 NM_006142
SFN
stratifin
chr6_+_130758261 0.216 NM_052913
TMEM200A
transmembrane protein 200A
chr3_-_123339423 0.216 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr15_-_40600065 0.215 PLCB2
phospholipase C, beta 2
chr17_+_28268622 0.214 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr7_-_112727799 0.214 GPR85
G protein-coupled receptor 85
chr12_-_123201319 0.214 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr6_-_133035180 0.214 NM_004666
VNN1
vanin 1
chr4_-_155511838 0.204 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr2_+_62900985 0.202 NM_001142615
EHBP1
EH domain binding protein 1
chr3_+_188889762 0.202 NM_198485
TPRG1
tumor protein p63 regulated 1
chrX_-_10588458 0.201 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr5_+_80529138 0.200 NM_001099735
NM_001099736
NM_001825
CKMT2


creatine kinase, mitochondrial 2 (sarcomeric)


chr11_+_34642587 0.198 NM_001206615
NM_012153
EHF

ets homologous factor

chr7_+_143701021 0.198 NM_001005281
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chrX_+_69664704 0.197 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr5_+_109025135 0.196 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr5_-_137071703 0.191 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chrX_+_16141423 0.189 NM_005314
GRPR
gastrin-releasing peptide receptor
chr3_-_150966901 0.187 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr1_+_118472364 0.186 NM_006784
WDR3
WD repeat domain 3
chr14_-_24047993 0.182 NM_001146028
NM_032452
JPH4

junctophilin 4

chr6_+_31430955 0.180 HCP5
HLA complex P5 (non-protein coding)
chrX_-_103268231 0.178 NM_001002916
H2BFWT
H2B histone family, member W, testis-specific
chr10_-_62149487 0.177 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr17_-_70116928 0.176 FLJ37644
uncharacterized LOC400618
chr8_-_42234562 0.172 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr8_-_17555158 0.170 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr4_-_87028805 0.170 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr11_+_57529233 0.169 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chr1_-_7973286 0.169 UTS2
urotensin 2
chr22_-_39640956 0.169 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide
chr7_+_150725502 0.168 NM_007188
ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr6_-_75965845 0.168 TMEM30A
transmembrane protein 30A
chr4_-_151770611 0.167 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr22_-_28315214 0.167 NM_012399
PITPNB
phosphatidylinositol transfer protein, beta
chr7_-_112727778 0.165 GPR85
G protein-coupled receptor 85
chr7_-_27205148 0.160 NM_152739
HOXA9
homeobox A9
chr2_-_69180011 0.157 NM_182536
GKN2
gastrokine 2
chr4_-_38806410 0.157 NM_003263
TLR1
toll-like receptor 1
chr8_+_24771276 0.156 NEFM
neurofilament, medium polypeptide
chr15_-_68498373 0.156 NM_001031733
NM_033429
CALML4

calmodulin-like 4

chr17_-_38073792 0.155 NM_018530
GSDMB
gasdermin B
chr7_-_50633042 0.155 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr6_-_24358279 0.154 NM_016356
DCDC2
doublecortin domain containing 2
chr7_-_113559048 0.154 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr22_+_22735134 0.152 CYAT1
immunoglobulin lambda light chain-like
chr19_+_4007690 0.149 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr17_+_73720775 0.148 NM_001005619
ITGB4
integrin, beta 4
chr7_+_137761177 0.148 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr6_+_26217145 0.148 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr7_-_82072804 0.147 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr11_-_62752370 0.146 NM_004790
NM_153276
NM_153277
NM_153278
SLC22A6



solute carrier family 22 (organic anion transporter), member 6



chr7_+_89843133 0.145 NM_001040666
STEAP2
STEAP family member 2, metalloreductase
chr7_-_27205123 0.144 HOXA9
homeobox A9
chr17_-_26127474 0.144 NM_000625
NOS2
nitric oxide synthase 2, inducible
chr2_+_98703594 0.143 NM_144992
VWA3B
von Willebrand factor A domain containing 3B
chr6_-_116381765 0.140 NM_002031
FRK
fyn-related kinase
chr3_-_119812973 0.140 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta

chr1_+_111413820 0.140 NM_001040033
CD53
CD53 molecule
chr7_+_63773185 0.139 NM_001170905
ZNF736
zinc finger protein 736
chr1_+_220701523 0.137 MARK1
MAP/microtubule affinity-regulating kinase 1
chr8_-_17580024 0.136 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chrX_+_17393537 0.135 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr18_-_3874252 0.135 NM_001242764
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr8_+_24771268 0.134 NM_005382
NEFM
neurofilament, medium polypeptide
chr1_-_42384326 0.133 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr11_+_124120422 0.132 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr10_+_71211215 0.130 NM_012339
TSPAN15
tetraspanin 15
chr13_-_46756291 0.125 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_140201221 0.123 NM_018908
NM_031501
PCDHA5

protocadherin alpha 5

chr12_-_371994 0.123 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chr11_-_8892909 0.119 ST5
suppression of tumorigenicity 5
chr4_+_41540187 0.119 LIMCH1
LIM and calponin homology domains 1
chr11_+_112047088 0.117 NM_001037290
BCO2
beta-carotene oxygenase 2
chr3_-_112693711 0.117 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr17_-_3496122 0.117 NM_080706
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chrX_+_64708614 0.116 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chrX_-_72434623 0.116 NAP1L2
nucleosome assembly protein 1-like 2
chr13_-_75901897 0.114 TBC1D4
TBC1 domain family, member 4
chr1_+_210001363 0.114 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr6_+_154331630 0.114 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chrX_-_72434667 0.112 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chr6_+_47666288 0.111 NM_153838
GPR115
G protein-coupled receptor 115
chr17_+_11924116 0.109 NM_003010
MAP2K4
mitogen-activated protein kinase kinase 4
chr12_+_50017340 0.108 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr12_-_24102563 0.108 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr8_+_26150731 0.108 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr22_+_22735207 0.107 IGLJ3
immunoglobulin lambda joining 3
chr9_-_95055913 0.106 IARS
isoleucyl-tRNA synthetase
chr1_+_43766565 0.105 NM_001253357
NM_005424
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr18_-_22930826 0.104


chr2_-_165551178 0.104 COBLL1
COBL-like 1
chr2_+_103378489 0.104 NM_144632
TMEM182
transmembrane protein 182
chr3_-_158450271 0.104 NM_002888
NM_206963
RARRES1

retinoic acid receptor responder (tazarotene induced) 1

chr21_+_45905447 0.103


chr14_+_97263681 0.103 NM_003384
VRK1
vaccinia related kinase 1
chr19_+_14640413 0.103 TECR
trans-2,3-enoyl-CoA reductase
chr1_-_33282844 0.102 YARS
tyrosyl-tRNA synthetase
chr12_-_52761254 0.101 NM_002283
KRT85
keratin 85
chr4_+_71494460 0.101 NM_031889
ENAM
enamelin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 3.35e-02 GO:0032501 multicellular organismal process

Nothing significant found in compartment category.

Nothing significant found in function category.